monarch-docs/docs/input_files/human.json

{
  "Metadata (not used for simulation)": {
    "description": "Human with single patch per wall, and growth driven by pressure overload (through Ras)",
    "references": [""],
    "notes": ""
  },

  "Circulation": {
    "hr": 75,
    "sbv": 1500,
    "k": [0.10,  0.05,  0.10,  0.05, 0.30,  0.05, 0.10,  0.25]
  },

  "Capacitances": {
    "cvp": 8.0,
    "cas": 1.12,
    "cvs": 70.0,
    "cap": 13.0
  },

    "Resistances": {
    "rvp": 0.015,
    "rcs": 0.090,
    "ras": 0.900,
    "rvs": 0.015,
    "rcp": 0.020,
    "rap": 0.300,
    "rav": 0.025,
    "rmvb": 1e20,
    "rtvb": 1e20
  },

  "Solver": {
    "cutoff": 0.01,
    "iter_max": 50,
    "n_inc": 1800
  },

  "Heart": {
    "patches": [0, 1, 2, 3, 4],
    "am_ref": [ 7920, 10800, 4160, 5520, 4000],
    "wv": [58200, 36368, 41896, 5752, 2552],
    "ls_ref": [2.0, 2.0, 2.0, 2.0, 2.0],
    "ls_eiso": [0.04, 0.04, 0.04, 0.04, 0.04],
    "lsc0": [1.51, 1.51, 1.51, 1.51, 1.51],
    "v_max": [7e-3, 7e-3, 7e-3, 14e-3, 14e-3],
    "tr": [0.25, 0.25, 0.25, 0.40, 0.40],
    "td": [0.25, 0.25, 0.25, 0.40, 0.40],
    "tad": [200, 200, 200, 80, 80],
    "sf_act": [0.150, 0.150, 0.150, 0.060, 0.060],
    "c_1": [1e-5, 1e-5, 1e-5, 1.60e-3, 1.60e-3],
    "c_3": [5.23e-4, 5.23e-4, 5.23e-4, 0.017e-3, 0.017e-3],
    "c_4": [10.0, 10.0, 10.0, 10.0, 10.0],
    "t_act": [100, 100, 100, 0, 0],
    "ischemic": [0, 0, 0, 0, 0]
  },

  "Pericardium": {
    "thickness": 0.0,
    "c_1": 1.59e-1,
    "c_3": 8.41e-3,
    "c_4": 3.47e1,
    "pre_stretch": 1.0
},

  "Growth": {
    "type": "transverse_jones",
    "time": [-1, 0, 1, 6, 11, 16, 21, 26, 31, 36, 41, 46, 51, 56, 61, 66, 71, 76, 81, 86, 91, 96, 101, 106, 111, 116, 121, 126, 131, 136, 141, 146, 151, 156, 161, 166, 171, 175, 181],
    "hr": [75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75],
    "rmvb": [1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10],
    "sbv": [1800, 1800,  1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800],
    "ras": [0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900],
    "ischemic": [
      {
        "ischemic": [0, 0, 0, 0, 0],
        "t_init": 0
      }
    ],
    "t_act": [
      {
        "t_act": [100, 100, 100, 0, 0],
        "t_init": 0
      }
    ],
    "tau_f+": 1.0,
    "tau_f-" : 1e5,
    "tau_r+": 1e5,
    "tau_r-": 5.0,
    "gamma": 2.0,
    "theta_f_max": 2.25,
    "theta_f_min": 0.75,
    "theta_r_max": 1.5,
    "theta_r_min": 0.75,
    "t_mem": 10000,
    "growing_walls": [0, 1, 2]
  }
}