FlashPPI: Linear-time prediction of proteome-scale microbial protein interactions

This model is used for benchmarking on the held out E. coli benchmark set (https://huggingface.co/datasets/tattabio/ecoli_pdb_benchmark). See the paper details on benchmarking.

The model trained on the full set is available here: https://huggingface.co/tattabio/flashppi.

Citing

If you use FlashPPI or our datasets in your research, please cite:

@article{
  doi:10.1073/pnas.2610619123,
  author = {Andre Cornman  and Matt Tranzillo  and Nicolo G. Zulaybar  and Imane Bouzit  and Yunha Hwang },
  title = {Linear-time prediction of proteome-scale microbial protein interactions},
  journal = {Proceedings of the National Academy of Sciences},
  volume = {123},
  number = {25},
  pages = {e2610619123},
  year = {2026},
  doi = {10.1073/pnas.2610619123},
  URL = {https://www.pnas.org/doi/abs/10.1073/pnas.2610619123},
  eprint = {https://www.pnas.org/doi/pdf/10.1073/pnas.2610619123},
}
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