code from https://docs.vllm.ai/en/latest/features/quantization/gguf.html

from vllm import LLM, SamplingParams

# In this script, we demonstrate how to pass input to the chat method:
conversation = [
   {
      "role": "system",
      "content": "You are a helpful assistant"
   },
   {
      "role": "user",
      "content": "Hello"
   },
   {
      "role": "assistant",
      "content": "Hello! How can I assist you today?"
   },
   {
      "role": "user",
      "content": "Write an essay about the importance of higher education.",
   },
]

# Create a sampling params object.
sampling_params = SamplingParams(temperature=0.8, top_p=0.95)

# Create an LLM.
llm = LLM(model="unsloth/DeepSeek-R1-Distill-Qwen-32B-GGUF",
         tokenizer="Qwen/Qwen2.5-32B-Instruct")
# Generate texts from the prompts. The output is a list of RequestOutput objects
# that contain the prompt, generated text, and other information.
outputs = llm.chat(conversation, sampling_params)

# Print the outputs.
for output in outputs:
   prompt = output.prompt
   generated_text = output.outputs[0].text
   print(f"Prompt: {prompt!r}, Generated text: {generated_text!r}")

modify model and tokenizer
raise a error:

OSERROR: It looks like the config file at 'xxxx/DeepSeek-R1-Distill-Qwen-32B-Q4_K_M.gguf' is not a valid JSON file.

Question

this gguf not supported by vllm?

GGUF was just supportedfor DeepSeek. Follow along the issue here: https://github.com/vllm-project/vllm/issues/12573

Thank you for reply. I get it.