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|---|---|---|---|---|---|---|---|---|---|---|---|---|
094026d4-ed29-4fac-b81a-062e2acc9c5f | Lary ngoscopes are sterilized by - | Glutaraldehyde | Formalin | Betadine | Boiling | 0a | single | Ans. is 'a' i.e., Glutaraldehyde o Laryngoscope should be cleaned before and after use with spirit.o Disinfection can be done once a day by removing the bulb and immersing the blade in 2% cidex (glutaraldehyde) for 10 minutes.o They should be sterilized once a week by immersing in cidex for 10 hours or by autoclaving. | Microbiology | General | [
"glutaraldehyde",
"betadine"
] | 48,763 |
019fe1f6-37b6-4bfd-94ad-b11c6106f7df | Positive fluorescein dye disappearance test indicates that watering eye is due to: | Atonia of the sac | Mechanical obstruction in the lacrimal passages | Both of the above | None of the above | 2c | multi | Ans. Both of the above | Ophthalmology | null | [
"fluorescein"
] | 48,782 |
e75e7867-b670-4768-8e1c-ccaa271ea3df | The drug which does not cause myopathy is : | Chloroquine | Betamethasone | Chloramphenicol | Zidovudine | 2c | single | Ans. is 'c' Chloramphenicol Drugs Causing MyopathyAmphotericin BCarbenoxoloneCimetidineChloroquineClofibrateGlucocorticoidGrowth hormoneZidovudineOral contraceptivesHMG COA reductase inhibitors.InfliximabInterferon alpha | Pharmacology | Adverse Drug Effect | [
"chloramphenicol",
"chloroquine",
"zidovudine"
] | 48,811 |
d44fdb2f-cb94-4cdc-b0ff-547cd83e47a0 | Which of the following supplements is used in the treatment of multiple carboxylase deficiency? | Biotin | Pyridoxin | Thiamine | Folic acid | 0a | single | Biotin is a water soluble vitamin that is a cofactor for all carboxylase enzymes. Multiple carboxylase deficiency results from deficient carboxylase activity and is treated by biotin. Ref: Nelson's Textbook of Pediatrics 17th Edition, Page 412; Textbook of Clinical Pediatrics, Volume 1 By A. Y. Elzouki, F. B. Stapleton... | Biochemistry | null | [
"biotin"
] | 48,816 |
b937f0c2-6060-4ec7-b6cc-2712fa55d973 | A-female patint of childbearing age is on valproate for JME. Whichk drug should be used to replace valproate and can be prescribed as montherapy? | Levetiracetam | Zonisamide | Carbamazepine | Phenytoin | 0a | single | It is known to cause serious abnormalities in the baby if taken during pregnancy. Because of this it is not typically recommended in women of childbearing age who have migraines. Common side effects include sleepiness, dizziness, feeling tired, and aggression. Severe side effects may include psychosis, suicide, and all... | Medicine | C.N.S | [
"valproate",
"zonisamide",
"carbamazepine",
"phenytoin"
] | 48,821 |
b5c74b47-8318-445e-9d56-eda7993d45bb | The tricyclic antidepressant with LEAST autonomic and cardiotoxic effects: March 2004 | Amitriptyline | Desipramine | Lofepramine | Protriptyline | 2c | single | Ans. C i.e. Lofepramine | Psychiatry | null | [
"amitriptyline",
"desipramine"
] | 48,825 |
9ebeb51e-0756-48b8-9641-597070a313f4 | Pyruvate dehydrogenase complex contains all except | Biotin | NAD | FAD | CoA | 0a | multi | Pyruvate dehydrogenase complex--thiamin diphosphate, lipoate, NAD+, FAD, and CoA Reference: Harper; 30th edition; Page no: 163 | Biochemistry | Metabolism of carbohydrate | [
"biotin"
] | 48,830 |
31f78e60-285f-4f4d-a72d-4999e2214b24 | Most characteristic arrhythmia seen with Digoxin toxicity is | Ventricular Extrasystoles | Ventricular bigemini | Atrial tachycardia with AV nodal block | Atrial flutter | 2c | single | Atrial tachycardia (because of increase intracellular calcium levels) and AV nodal blockade (because of parasympathomimetic activity) is the most characteristic arrhythmia seen with Digoxin toxicity.
But Ventricular bigeminy is the most common arrythmia seen with Digoxin toxicity. | Pharmacology | null | [
"digoxin"
] | 48,840 |
ff02cf15-fe9d-4a2d-95b6-f48bdf033bea | Treatment of transverse lies at labour is | Artificial rupture of membrane | Oxytocin infusion | Caesarean section | Forceps delivery | 2c | single | (Caesarean section): Ref: 393, 397-DTRANSVERSE LIE: - When the long axis of the fetus lies perpendicularly to the maternal spine or centralized uterine axis it is called transverse lies* In dorso-posterior, chance of fetal extension is common with increased risk of arm prolopse, left one being common than right* Dorso-... | Gynaecology & Obstetrics | Miscellaneous (Gynae) | [
"oxytocin"
] | 48,842 |
6d631fc9-0630-4f69-b84b-aee48feae4ef | All drugs decrease the moality in hea failure except: | Metoprolol | Enalapril | Telmisaan | Digoxin | 3d | multi | Digoxin is used in acute CHF as well as maintenance therapy but do not retard cardiac remodelling or prolong survival in CHF patients Drugs that decrease the cardiac remodeling in a patient with CHF decrease the moality. They are: Beta blockers (metoprolol, bisoprolol) ACE inhibitors (enalapril) ARB (telmisaan) Aldoste... | Pharmacology | Hematology and CVS | [
"digoxin",
"metoprolol",
"enalapril"
] | 48,856 |
3d4bbe15-a6f2-4dff-85c6-04cb23c3fc44 | Which of the following drug is given for pulmonary hypeension? | Carboprost | Mispoprostol | Indomethacin | Bosentan | 3d | single | Endothelin Antagonists (DOC) - Bosentan - Ambresenton - Macisentan If these are not effective then drugs used are Phosphodiesterase inhibitors like sildenafil and tadalafil. Prostaglandins - Iloprost (Not given orally) Selexipag (Prostacyclin Agonist) - PGI2 Agonist - Given orally | Pharmacology | Histamine, 5-HT and PGs | [
"carboprost",
"indomethacin",
"bosentan"
] | 48,879 |
cdb94e0e-f82e-41a2-ab55-0fb27cff201e | Exenatide is drug prescribed for which disease: | Osteoporosis | Diabetes | Hyperthyroidism | Infertility | 1b | single | Ans. B. DiabetesExenatide is new drug which is a GLP -1 analogue. It delays the gastric emptying, has a role in appetite control and also release of insulin. It controls post prandial hyperglycemia. | Pharmacology | Endocrinology | [
"exenatide"
] | 48,902 |
3944273a-7e50-44f8-bc42-59622f4f8aa6 | Interaction of theophylline with ciprofloxacin is : | Ciprofloxacin increases theophylline metabolism | Ciprofloxacin decreases theophylline metabolism | Theophylline increases ciprofloxacin metabolism | Theophylline decreases ciprofloxacin metabolism | 1b | single | null | Pharmacology | null | [
"theophylline",
"ciprofloxacin"
] | 48,909 |
3a35a82b-5025-4286-97ae-d5556651f4c7 | How to differentiate between psychological and organic erectile dysfunction? | Nocturnal penile tumescence | PIPE test | Sildenafil-induced erection | Squeeze technique | 0a | single | Presence of early morning erections and erection during REM sleep (nocturnal erection) are suggestive of psychogenic erectile dysfunction as there is no anxiety. Whereas, a patient with organic erectile dysfunction (due to vascular or neurological causes) would not have erections even during sleep. Investigations, such... | Psychiatry | Sexual Disorders | [
"sildenafil"
] | 48,913 |
09192c6f-03ce-4d8c-8343-1f51fbfc404a | Drugs used in migraine prophylaxis are all except: | Flunarizine | Propanolol | Cyproheptadine | Sumatriptan | 3d | multi | Drugs used for migraine prophylaxis: - A : Antiepileptic drug- B : Beta blocker : Propranolol, botulinum toxin- C : CCB: flunarizine, cyproheptadine, clonidine For acute migraine attack : We give sumatriptan and ergotamine.Triptans are contraindicated in patient with coronary aery disease due to it's vasospasm effect. | Pharmacology | Histamine, 5-HT and PGs | [
"sumatriptan",
"cyproheptadine"
] | 48,919 |
ebeae449-4bdc-489e-a470-7b75ef9a160e | Opiate withdrawal is treated with - | CPZ | Nalorphine | Pethidine | Methadone | 3d | single | Treatment of opioid (Morphine or heroin) withdrawal (detoxification):- Methadone is the DOC. Alternatives are clonidine, clonidine with naltrexone with or without BZDs, Lofexidine, dextropropoxyphene, diphenoxylate. | Psychiatry | null | [
"pethidine",
"methadone"
] | 48,926 |
94d6faaf-7382-41f0-9f06-437956ba9f04 | Most common mode of treatment of a 1 year old child with asthma is - | Inhaled sho acting beta 2 agonist | Oral sho acting theophylline | Oral ketotifen | Leukotriene agonist | 0a | single | Ans. is 'a' i.e., Inhaled sho acting beta 2 agonists Treatment ofAsthma a Treatment of asthma can be divided into ? A) Treatment of chronic asthma B) Treatment of acute excarhation ? a) Treatment of mild, moderate or severe exacerbation b) Treatment of life threatening exacerbation (status asthmaticus) Treatment of chr... | Pediatrics | null | [
"ketotifen",
"theophylline"
] | 48,930 |
ba795a1c-0fce-45d8-b955-ee88cb1b1051 | Alcohol, salicylates and pilocarpine can be used as: Odisha 11 | Chelating agents | Diaphoretics | Purging | Forced alkaline diuresis | 1b | single | Ans. Diaphoretics | Forensic Medicine | null | [
"pilocarpine"
] | 48,940 |
d3d7d5c6-d948-4bbc-ba2a-ba94afdd29db | Opioid with rnonoarnine action is? | Tramadol | Pentazocine | Pethidine | Meperidine | 0a | single | Tramadol REF: Principles and practice of palliative care and suppoive oncology By Ann M. Berger, John L. Shuster, Jamie H. Von Roenn page 51 "Tramadol is synthetic analog of codeine that binds to the MOR (Mu opioid receptor) and blocks reuptake of serotonin and nor epinephrine. As a result of monoamine action naloxone ... | Pharmacology | null | [
"pentazocine",
"pethidine",
"tramadol"
] | 48,954 |
b1330de3-5c18-4cda-9947-3b5fd695eb34 | Following drug interact with cefotaxime - | Digoxin | Paracetamol | Loop diuretics | Nifedipine | 2c | single | Ans. is 'c' i.e., Loop diuretics o Nephrotoxicity of cephalosporins is accentuated by concurrent administration of a loop diuretic. | Pharmacology | null | [
"cefotaxime",
"paracetamol",
"nifedipine",
"digoxin"
] | 48,977 |
c28eef3e-db44-4c59-a8b2-6bf401163708 | Which of the following induction agent is used to produce a `street-fit' person following surgery – | Midazolam | Propofol | Alfentanyl | Thiopentone | 1b | single | Amongst the given options only propofol & thiopentone are inducing agents.
Propofol is the inducing agent of choice for day care surgery (street-fit following surgery). | Anaesthesia | null | [
"midazolam",
"propofol"
] | 49,010 |
1e9fcec4-3362-4a71-b213-5f100dfc7789 | Which of the following is a Dihydropteroate synthase (DHPS) inhibitor? | Pyrimethamine | Trimethoprim | Methotrexate | Dapsone | 3d | single | Dapsone, PAS, Sulphonamide > inhibit DHPS enzyme Pyrimethamine, Methotrexate, Trimethoprim - acts by inhibiting DHFR (Dihydrofolate reductase) enzyme. | Pharmacology | null | [
"methotrexate",
"trimethoprim",
"dapsone"
] | 49,028 |
7a9cbd01-ea0a-4d28-8896-02df79aefb23 | In the management of patients with Vincent's infection, the preferred therapeutic agents are | Hydrogen peroxide mouthwash and metronidazole | Cephalosporins and hydrogen peroxide mouthwash | Chtorhexidine mouthwash and metronidazole | Crystalline penicillin and chlorhexidine mouthwash | 0a | multi | null | Dental | null | [
"metronidazole",
"chlorhexidine"
] | 49,035 |
317fbdf9-6524-4867-9f5b-74d24966767f | The prophylactic antibiotic indicated to prevent infection in lymphoedema is : | Vancomycin | Penicillin | Amikacin | Quinolones | 0a | single | null | Pharmacology | null | [
"amikacin",
"vancomycin"
] | 49,038 |
8ba3627e-87cf-49ca-b379-a8c67bde3718 | Shortest acting mydriatic and cycloplegic: | Cyclopentolate | Atropine | Homatropine | Tropicamide | 3d | single | Ans. D. TropicamideMydriatic action is useful for fundus examination and cycloplegic is useful for correct measurement of refractive error.Atropine is longest acting and tropicamide is shortest acting drug Anticholinergic drugs are contraindicated in Glaucoma. | Pharmacology | Gram-Positive Infections - Corynebacterial Infections | [
"atropine",
"tropicamide"
] | 49,048 |
fd583bec-af86-47e2-9263-79e1d1811aaa | Rituximab is used in all EXCEPT : | Non Hodgkins lymphoma | Paroxysomal nocturnal hemoglobinurea | Rheumatoid arthritis | Systemic lupus erythematosis | 1b | multi | null | Pharmacology | null | [
"rituximab"
] | 49,055 |
00ccbfce-7492-4853-8dba-42b7569f0564 | The Antiepileptic drug, Phenytoin therapeutic blood level is | 0-9 mcg/ml | 10-19 mcg/ml | 20-29 mcg/ml | 30-39 mcg/ml | 1b | single | (B) 10-19 mcg/ml# SERUM PHENYTOIN LEVELS:> Therapeutic range is 10-20 mcg/mL.# Total phenytoin levels (mcg/mL) - Typical corresponding Signs & Symptoms: Lower than 10- Rare Between 10 and 20 - Occasional mild nystagmus Between 20 and 30 - Nystagmus Between 30 and 40 - Ataxia, slurred speech, nausea, and vomiting Betwee... | Medicine | Miscellaneous | [
"phenytoin"
] | 49,081 |
d7567844-92df-4024-9f8f-fca65a75b1f4 | Which is the diuretic of choice in patients of pulmonary edema- | Furosemide | Thiazide | Spironolactone | Amiloride | 0a | single | Ans. is 'a' i.e., Furosemide Pharmacological treatment of acute pulmonary edema* Acute left ventricular failure and pulmonary edema is a medical emergency.* In acute left ventricular failure, there is accumulation of fluid in lungs - acute pulmonary edema.* Loop diuretics (Furosemide) is the DOC for acute pulmonary ede... | Pharmacology | Diuretic | [
"spironolactone",
"furosemide"
] | 49,082 |
2e1eaed6-f949-4b98-820e-b2af653288a0 | Syringes and glassware are sterilized by? | Irradiation | Autoclave | Hot air oven | Glutaraldehyde | 2c | single | Hot air oven REF: Ananthnarayan 8th e p. 35 Procedures of sterilization of some impoant materials Glasswares, syringes, petridishes, test tubes, flasks, surgical instruments, oily fluids and powders Hot air oven Serum, body fluids, bacterial vaccines Waterbath , vaccine bath Milk Pasteurization at 63deg c x 30 mins or ... | Surgery | null | [
"glutaraldehyde"
] | 49,099 |
f9e02e89-e8ca-4c35-bc36-d6653ac50db2 | Drug of choice for poisoning with Amanita muscaria | Atropine | Physostigmine | Diazepam | Pencillin | 2c | single | Amanita muscaria signs and symptoms are mainly related to anxiety and insomnia which can be treated best with benzodiazepines like diazepam Atropine is contraindicated but for amanita inocybe poisoning atropine is drug of choice Ref: KDT 6th ed pg 98 | Pharmacology | Autonomic nervous system | [
"atropine",
"physostigmine",
"diazepam"
] | 49,113 |
cd75aaf3-5325-4053-ae04-81c36574fa21 | The addition of hyaluronidase to a local anesthetic solution might | Increase the duration of anesthesia | Limit the area of anesthesia | Reduce bleeding | Enhance diffusion of local anesthetic | 3d | single | null | Surgery | null | [
"hyaluronidase"
] | 49,114 |
81bbfec2-cd68-4f50-a625-6474626df761 | Mrs. Reeta Wardhan, A 50-year old female with rheumatoid arthritis is being considered for infliximab therapy. Which of the following tests should be performed before beginning treatment? | Liver function tests | PPD skin test | Pulmonary function tests | Visual examination | 1b | single | Infliximab is a monoclonal antibody against TNF-α. It is commonly used to treat moderate to severe rheumatoid arthritis particularly in patients who have failed methotrexate therapy. TNF-α inhibitors can cause serious adverse effects, including reactivation of latent tuberculosis. All patients being considered for TNF... | Pharmacology | null | [
"infliximab"
] | 49,115 |
3730cef6-56b6-4d93-996c-d757c2cf92f8 | The drug of choice in the management of life threatening allergic reaction is: | Corticosteroids | Antihistamines | Adrenalin | Diazepam | 2c | multi | null | Pharmacology | null | [
"diazepam"
] | 49,122 |
d3b92e69-d67f-48cb-b93b-9a259ca8d0cb | A gravida 3 with a history of 2 previous 2nd trimester aboions presents at 22 weeks of gestation with funneling of the cervix. Most appropriate management would be: | Administer Dinoprostone and bed rest | Administer mifepristone and bed rest | Apply Fothergill's stitch | Apply McDonald's stitch | 3d | single | Previous history of mid trimester aboions and funneling of cervix are both suggestive of incompetent cervix McDonald's stitch is used for cervical encerclage, generally applied after 12 completed pregnancy weeks and removed at or beyond 37 weeks Dinoprostone is mainly used for induction of labour. Mifepristone which is... | Gynaecology & Obstetrics | Aboions, Spontaneous & Induced Emergency Contraception (Hey,whats the hurry !) | [
"mifepristone",
"dinoprostone"
] | 49,123 |
01f38679-d797-4d9f-9eb5-497c87723afa | Drug of choice for the treatment of a pregnant woman with P vivax malaria is : | Quinine | Chloroquine | Artemether | Paracetamol | 1b | single | null | Pharmacology | null | [
"quinine",
"paracetamol",
"chloroquine"
] | 49,136 |
b866d93f-aec0-4401-822d-6f02c6dd4371 | Treatment of choice for Echinococcus granulosus is. | Albendazole | Mebendazole | Thiobendazole | Praziquantel | 0a | single | Answer is A (Albendazole): The drug of choice for treatment of Echinococcus granulosus injection (Hydatid cyst) is Albendazole. | Medicine | null | [
"albendazole",
"mebendazole"
] | 49,164 |
3b038236-a75a-4281-8bb1-410a841a0010 | When used for emergency contraception, What is the dose of ulipristal acetate? | 300mg | 30mg | 300ug | 30ug | 1b | single | Emergency Contraceptives Drug Dose Levonorgestrel (POP) 1 dose 1.5 mg within 72 hrs Copper IUDs ( NOT THE DOC ! ) Inseion within 5 days Ulipristal acetate (SPRM) 30 mg orally within 120 hours Ethinyl estradiol 50 ug + Norgestrel 0.25 mg (COC) 2 tab stat and 2 after 12 hour Mifepristone RU 486 (PA) 25 to 100 mg single d... | Gynaecology & Obstetrics | NEET 2019 | [
"ulipristal"
] | 49,220 |
8d7336c0-9c1f-4642-8ad3-af9d070141c6 | Effective ulcer treatment that works by inhibitory action on gastric acid secretion is - | Lactulose | Aluminium hydroxide | Sucralfate | Ranitidine | 3d | single | Ans. is 'd' i.e., Ranitidine o Among the given options, only ranitidine decreases acid secretion.Drugs for peptic ulcer1.Reduce gastric acid secretionH2 antihistaminic - Cimetidine, Ranitidine, Famotidine, Roxatidine.Proton pump inhibitors - Omeprazole, Lansoprazole, Pantoprazole, Rabeprazole, Esomeprazole.Anticholiner... | Pharmacology | G.I.T | [
"lactulose",
"ranitidine"
] | 49,251 |
e0fba5e9-2d96-486e-b9c6-1ecf49c0f048 | One of the following antihypeensive is NOT used in pregnancy: | Enalapril | Methyldopa | Hydralazine | Nifedipine | 0a | single | Enalapril is an ACE INHIBITOR which causes oligohydramnios, hypocalvaria and renal dysfunction which leads to IUGR. Commonly Used Drugs in the Management of Pre-eclampsia Drug Mode of action Labetalol Adrenoceptor antagonist (a and b blockers) Nifedipine Calcium channel blocker Methyl-dopa Central and peripheral anti a... | Gynaecology & Obstetrics | Pregnancy induced Hypeension | [
"methyldopa",
"hydralazine",
"nifedipine",
"enalapril"
] | 49,255 |
d2092992-012b-49e3-b22d-15ff0381db58 | Glycoprotein II b / III a receptor antagonists is | Clopidogrel | Abeiximab | Tranoxaemic-acid | Ticlopidine | 1b | single | (Abciximab) (573-KDT) (610-11-KDT 6th)Antiplatelet Drugs (Antithrombotic drugs)* Aspirin* Dipyridamole* Ticlopidine* Clopidogrel* * Glycoprotein lib /Ilia receptor antagonists - Abciximab, Eptifibatide and TirofibanAbciximab* Given along with aspirin + heparin during PTC A it has markedly reduced the incidence of reste... | Pharmacology | Hematology | [
"clopidogrel",
"ticlopidine"
] | 49,288 |
e01c0216-2606-464b-949d-c3e4c9a5e027 | Fatty change in liver is seen with use of - | Tetracycline | Erythromycin | Chlorpromazine | Acetoaminophen | 0a | single | null | Pathology | null | [
"erythromycin",
"chlorpromazine",
"tetracycline"
] | 49,289 |
f45139c3-9908-4f4d-a762-a5dd078d603c | Which of the following is shortest acting non depolarizing Muscle Relaxant: | Vecuronium | Mivacurium | Succinylcholine | Atracrium | 1b | single | Ans: (b) MivacuriumRef: KDt 6th ed. / 343* Shortest acting non-depolarizing muscle relaxant: Mivacurium* Shortest acting depolarizing muscle relaxant: Sch* Overall shortest acting muscle relaxant: Sch.* Shortest acting local anaesthetic: chlorprocaineClassification of Muscle RelaxantsNeuro Muscular Blocking agentDepola... | Anaesthesia | Non-depolarising Neuromuscular Blocking Agents | [
"vecuronium",
"mivacurium"
] | 49,314 |
a6c7afb1-c6d3-4d60-a387-df23f60fc16e | Which of the following antihypertensives is not given in pregnancy? (AllMS May 2015. May 2014) | Enalapril | a-methyldopa | Labetalol | Nifedipine | 0a | multi | Ans. a. Enalapril (Ref: Goodman and Gilman 12/e pe p736)Enalapril is not given in pregnancy."ACE inhibitors inhibit the conversion of angiotensin-I to the potent vasoconstrictor angiotensin-II. They can cause severe fetal malformations that include hypocalvaria when given in the second and third trimesters. Because of ... | Gynaecology & Obstetrics | Management and Long-Term Consequences | [
"methyldopa",
"labetalol",
"nifedipine",
"enalapril"
] | 49,349 |
239f5443-f53e-414c-93b2-51219f6f4c19 | A 40 year old primiparous woman suspected to be suffering from endometriosis is subjected to diagnostic laparoscopy. Findings indicate - Uterus normal, both the ovaries show presence of chocolate cysts; endometriotic deposits are seen on the round ligament right side, both the fallopian tubes and the pouch of Douglas; ... | Total hysterectomy with bilateral salpingooophorectomy | Danazol therapy | Progesterone therapy | Fulguration of endometriotic deposits | 3d | multi | Ans. is d i.e. Fulguration of endometriotic deposits The situation given in the question is such that it points towards moderate endometriosis (as chocolate cyst, dense adhesions are present). Dense adhesions and cysts cannot be fully treated by medical therapy and so, some form of surgery is required. Main question is... | Gynaecology & Obstetrics | null | [
"danazol"
] | 49,353 |
7ecbb16b-0367-49ac-a857-17e99689864e | True regarding morphine | Tolerance develps for all except miosis and constipation | Tolerance to all effects develops with chronic usage | Tolerance develops for all except euphoria and sedation | Tolerance can develop to all effects in high doses | 0a | multi | A i.e. Toerance develops for all except miosis & constipation | Anaesthesia | null | [
"morphine"
] | 49,356 |
4696014a-a39a-45f6-acbe-7943be26d9ca | Which of the following is a low molecular weight heparin: | Hirudin | Enoxaparin | Tranexamic acid | Lepirudin | 1b | single | Ans. (b) Enoxaparin* Enoxaparin is a low molecular weight heparin.* It acts by inhibiting factor Xa.* LMWH usually doesn't need monitoring because of consistent bioavailability.* Drugs under LMWH:# Enoxaparin# Dalteparin# Tinzaparin# RabiparinAlso Know* Hirudin along with Lepirudin and Bivalirudin is an anticoagulant w... | Pharmacology | Anticoagulants and Coagulants | [
"enoxaparin"
] | 49,358 |
392e7d76-2372-4d9f-8e96-70f42ec89e95 | Which of the following antibiotics is NOT indicated for periodontal therapy? | Erythromycin | Metronidazole | Tetracycline | Augmentin | 0a | single | null | Dental | null | [
"erythromycin",
"metronidazole",
"tetracycline"
] | 49,368 |
8b214b00-10af-42b8-8128-b02dc11ea832 | Antidote for Strychnine poisoning is - | Barbiturates | Physotigmine | Fomepizole | Naloxone | 0a | single | Management of convulsions is impoant and can be treated by lorazepam or diazepam. If benzodiazepines are ineffective, sho acting barbiturate can be administered. Intractable convulsions may need muscle relaxants such as pancuronium. REF;THE SYNOPSIS OF FORENSIC MEDICINE:KS NARAYANA REDDY;28th EDITION;PAGE NO 353 | Forensic Medicine | Poisoning | [
"naloxone",
"fomepizole"
] | 49,369 |
294786c1-df91-4745-89c2-63499aef7ecf | Orally active hormone is | TSH | Thyroxine | GH | Prolactin | 1b | multi | Levothyroxine is an orally active hormone- T4 given daily on empty stomach in doses of 12.5, 25, 50,75 or 100 mcg depending on the clinical condition of hypothyroidism REF KD Tripathi 8th ed | Pharmacology | Endocrinology | [
"thyroxine"
] | 49,388 |
b00c2bd0-63a9-4b02-8be3-9997c46979cf | TADALAFIL false is ? | It is longest acting phosphodiesterase inhibitor | It cannot be used for the treatment of PAH | It is used in erectile dysfunction | Its half life is 17-5 hours | 1b | multi | Ans. is 'b' i.e., It cannot be used for the treatment of PAH Tadalafil is the longest acting phosphodiesterase inhibitor used for erectile dysfunction. Its half life is 17.5 hours. It can be used as once-daily phosphodiesterase type 5 (PDE5) inhibitor for the treatment of pulmonary aerial hypeension (PAH). | Pharmacology | null | [
"tadalafil"
] | 49,389 |
a14fb06d-8b86-4c25-b6e5-52db426a04d6 | All of the following drug inhibit the cell wall synthesis except: | Penicillin | Fosfomycin | Vancomycin | Tetracycline | 3d | multi | Ans. D. TetracyclineDrugs inhibiting the cell wall synthesis- beta lactam, bacitracin, vancomycin, cycloserine, Fosfomycin. Tetracycline acts via protein synthesis inhibition. | Pharmacology | Anti Microbial | [
"tetracycline",
"vancomycin"
] | 49,394 |
7e20471d-8638-45e4-949b-584f72b147c3 | Tadalafil acts on Phosphodiesterase 5 and causes accumulation of- | cAMP | cGMP | PAF | IL10 | 1b | single | Ans. is 'b'i.e., cGMP o Inhibition of PDE-5 prevents degradation of cGMP which results in accumulation of cGMP and marked potentiation of NO action - Relaxation of smooth muscle in corpus cavemosum and blood vessels supplying it - Erection of penis,o Drugs are : -SiledenafilTodafilVardenafil | Pharmacology | Asthma | [
"tadalafil"
] | 49,399 |
a2a98a90-f4bb-4a8c-aa65-348ffa4c8f63 | Which of the following is not given in the treatment of cyanotic spells in a patient of TOF? | Phenylephrine | Propranolol | Calcium chloride | Sodium bicarbonate | 2c | single | Ans. c. Calcium chloride (Ref: Ghai 7/e p410; Myong K. Park 5/e p238)Calcium chloride is not given in the treatment of cyanotic spells in a patient of TOF.Management of Anoxic Spells in Tetralogy of FallotKnee chest positionHumidified oxygenMorphineQ 0.1 to 0.2 mg/kg SCObtain venous pH; sodium bicarbonateQ 1-3 ml/kg (d... | Pediatrics | Cyanotic Congenital Heart Disease | [
"propranolol",
"phenylephrine"
] | 49,410 |
57c8d24e-6195-4890-bc94-7c746d4bd7b6 | An infant had a high-grade fever and respiratory distress at the time of presentation to the emergency room. The sample collected for blood culture was subsequently positive showing growth of alpha haemolytic colonies. On Gram staining, these were gram positive cocci. In the screening test for identification, the suspe... | Bactiracin | Novobiocin | Optochin | Oxacillin | 2c | single | Ans. is 'c' i.e. Optochin Respiratory tract infection in an infant, together with the presence of alpha hemolytic gram-positive cocci suggests the presence of Streptococcus pneumonia The sensitivity of pneumococci to optochin is useful in differentiating it from other alpha hemolytic streptococci. Streptococcus pneumon... | Unknown | null | [
"novobiocin"
] | 49,411 |
c2e97b61-d0ca-4391-89c4-d8b08f1355e5 | Which of the following drugs is not a pa of the &;Triple Therapy&; immunosuppression for post-renal transplant patients? | Cyclosporine | Azathioprine | FK 506 | Prednisolone | 2c | single | Initial therapy is the treatment given to all recipients (except where the donor is an identical twin) for 0-3 months after transplantation. Initial therapy is usually 'triple therapy', in which a calcineurin inhibitor (traditionally ciclosporin) is used as the 'primary agent'in combination with a coicosteroid (prednis... | Surgery | General surgery | [
"azathioprine",
"cyclosporine",
"prednisolone"
] | 49,428 |
1992c62c-7b55-4f29-bfa7-46d1bfc22c33 | Naltrexone is used for: | Cocaine | Alcohol dependence | Anorexia | Cannabis toxicity | 1b | single | Ans. B. Alcohol dependenceExplanationNaltrexone is a opioid receptor antagonist used to reduce or eliminate the subjective high associated with consumption of opioid and alcohol.It is approved by US FDA for alcohol dependence and for blockade of effects of exogenously administered opioids. | Psychiatry | Substance Abuse | [
"naltrexone"
] | 49,438 |
0d3f706c-ecbd-456d-a07f-04877090b001 | A 35-year-old smoker is involved in a house fire and receives a 45% total surface area burn. One half of the burned surface appears to be third degree. On the third post-burn day, the patient is noted to have bloody drainage from a nasogastric tube and a decrease of 5% in his hematocrit. Appropriate management should i... | Urgent upper gastrointestinal contrast study to delineate site of bleeding | Immediate selective aeriography the left gastric aery to diagnose and treat presumed stress ulceration | Urgent esophagogastroduodenoscopy to diagnosis the cause of bleeding | Urgent intravenous infusion of vasopressin at 0.2-0.4 IU/min | 2c | single | Patients who have sustained a major thermal burn of 35% or more of their body surface area are at a predictably high risk for the development of gastric erosions and hemorrhage. Endoscopy has demonstrated that gastric erosions are present in 93% of these patients, whereas the occurrence of severe acute upper gastrointe... | Surgery | Stomach & Duodenum | [
"vasopressin"
] | 49,440 |
4acdbe72-d0b1-455b-b136-d4edc37dffaa | Drug used in uncomplicated alcohol withdrawal? | Diazepam | Clonidine | Propanalol | Methadone | 0a | single | Ans. is 'a' i.e. Diazepam Medications used in Alcohol WithdrawlThe important point to emphasize about the treatment of Alcohol Withdrawl is that it is caused by the removal of a CNS depressant i.e. AlcoholSo the Withdrawl symptoms can be initially controlled by replacing alcohol with any other C.N.S. depressant drug an... | Pharmacology | C.N.S | [
"methadone",
"diazepam",
"clonidine"
] | 49,453 |
3d7441d9-de76-4377-a95c-f1ef7a206b02 | Haemolysis in G6PD (glucose 6 phosphate dehydrogenase) enzyme deficiency may occur with all of the following drugs except: | Primaquine | Phenacetin | Probenecid | Penicillin | 3d | multi | Ans. (d) Penicillin(Ref: Robbins 9th ed. Pg. 644-645)Penicillin causes hemolysis by mechanism of autoimmune hemolytic anemia and not G6PD deficiency mediated. | Pathology | Misc. (R.B.C) | [
"probenecid"
] | 49,475 |
4f6bf9ee-cee2-44be-b444-3bd4a6425aa4 | All of the following must be done for management of patient with the following ECG, except? | CPR for 60-90 seconds | Epinephrine | Vasopressin | Soda bicarbonate | 3d | multi | Ans. (d) Soda bicarbonate.* The rhythm strip shows a chaotic activity of ventricular fibrillation.* CPR for 60-90 seconds should be given with chest compressions times per minute if delay > 5 minutes on reaching the patient.* Epinephrine is given to improve coronary perfusion and reduce hypoxia which is responsible for... | Medicine | Arrhythmias | [
"epinephrine",
"vasopressin"
] | 49,479 |
83c2b200-d87a-4bbe-a367-5eed5aa9d3d9 | Longest acting muscle relaxant is? | Atracurium | Vecuronium | Doxacurium | Rocuronium | 2c | single | Ans. is 'c' i.e., Doxacurium Amongst the given options doxacurium is longest acting (Duration of action 90-120 minutes). Rocuronium (duration of action 30-60 minutes), Atracurium (duration of action 30-60 minutes) and vecuronium (duration of action 60-90 minutes) have shoer duration of action than doxacurium. | Pharmacology | null | [
"atracurium",
"vecuronium",
"rocuronium"
] | 49,484 |
6c15362a-7680-4586-95bb-92a53ccb974c | Which one of the following acts commonly both on parasympathetic and sympathetic division ? | Atropine | Pilocarpine | Acetylcholine | Adrenaline | 2c | multi | null | Pharmacology | null | [
"pilocarpine",
"atropine"
] | 49,488 |
15109a1e-ed23-4af7-ac1f-6a11c52211c3 | Most potent antiemitic agent used in preoperative period | Glycopyrolate | Hyoscine | Atropine | Metochlorpromide | 3d | single | D i.e. Metochlopromide Metochlopramide increases lower esophageal sphinter tone, speeds gastric emptying & lowers gastric fluid volume & decreases risk for aspiration pneumonia due to antiemetic effect | Anaesthesia | null | [
"atropine"
] | 49,506 |
5e587769-1313-4e62-bbaf-7833d96d725b | A child presents with infective skin lesion of the leg. Gram stain from the specimen shows pus cells with gram+ve cocci in chains and culture is done which shows hemolytic colonies. The test to confirm the organism is - | Bile solubility | Optochin sensitivity | Bacitracin sensitivity | Catalase positive | 2c | single | * Infective skin lesion with gram positive cocci in chains and hemolytic colonies suggest infection of Streptococcus pyogenes. Option 1, 2 Pneumococcus: Bile solubility Positive (Bile soluble) Optochin sensitivity Option 3 Streptococcus Pyogenes Transpo medium: Pike's medium Direct smear microscopy: Pus cells with gram... | Microbiology | Systemic Bacteriology Pa 1 (Gram Positive Cocci, Gram Negative Cocci) | [
"bacitracin"
] | 49,512 |
9b425f04-f5a8-458a-94b1-d970126899bc | Which of the following is not related to kala azar? | Pancytopenia | Oral miltefosine | Hyperpigmentation | Tropical splenomegaly syndrome | 3d | single | - Tropical splenomegaly syndrome is now known as Hyperreactive malarial syndrome (HMS) is prevalent in native residents of regions where malaria is endemic.Patients with HMS have high levels of antibody for Plasmodium falciparum, Plasmodium vivax, or Plasmodium ovale. - Presentation of Kala Azar -fever, chills and sple... | Medicine | parasitic infection | [
"miltefosine"
] | 49,519 |
cae1d27d-60bf-4e06-9dce-04ae5ee221f2 | Least teratogenic antiepileptic drug in pregnancy is; | Valproate | Phenytoin | Carbamazepine | Levetiracetam | 3d | single | Anti-epileptic with highest risk of teratogenicity - Valproate - causes neural tube defects Anti-epileptic with lowest risk of teratogenicity- Lamotrigine >Levetiracetam | Pharmacology | FMGE 2019 | [
"valproate",
"carbamazepine",
"phenytoin"
] | 49,526 |
daddeef9-f43c-46b7-8b30-4b7547be0ab9 | True statement about dezocine is: | It is slower acting than morphine | It is less potent than morphine | It acts GABA receptors | It doesn't increase histamine release | 3d | multi | Ref: Goodman and Gilman 10/e p602 *Dezocine is slightly more potent and faster acting opioid than morphine with a similar duration of action. It is a paial agonist antagonist opioid. *It is active at u receptors and side effect are similar to those of morphine. *Dezocine doesn't increase plasma histamine and produces l... | Pharmacology | Central Nervous system | [
"morphine"
] | 49,532 |
4b6f124b-fa88-4f14-a4a6-124dcdc47551 | The following drugs can produce ototoxicity except : | Ethacrynic acid | Aztreonam | Gentamicin | Frusemide | 1b | multi | null | Pharmacology | null | [
"gentamicin"
] | 49,539 |
a762ea03-7e3d-42cd-906a-d0360a157ceb | The most impoant channel of elimination of digoxin is: | Glomerular filtration | Tubular secretion | Hepatic metabolism | Excretion in bile | 0a | single | Digoxin is primarily eliminated unchanged by glomerular filtration Digitoxin is eliminated by hepatic metabolism. | Pharmacology | CHF, Angina Pectoris and Myocardial Infarction | [
"digoxin"
] | 49,546 |
7f6c304d-b573-43ec-9895-f56cc42ce5bf | A 7 - year - old boy underwent neurosurgery for craniopharyngioma following which pituitary functions were lost. Which of the following hormone should be replaced first? | Hydrocortisone | Thyroxine | Growth hormone | Prolactin | 0a | single | Hydrocortisone, followed by GH is vital to be given in a child with lost pituitary function. | Pediatrics | null | [
"thyroxine"
] | 49,547 |
aa51643c-0006-4001-9dcf-6c2f9ab56f85 | If a patient starts getting convulsions following the use of Lignocaine as local anaesthetic, the Drug of choice for the control of convulsions would be | Diazepam | Chlorpromazine | Scoline | Any | 0a | single | (A) Diazepam > If a patient starts getting convulsions following the use of Lignocaine as local anaesthetic, the Drug of choice for the cortrol of convulsions is the> diazepam# DIAZEPAM> Relatively lipid soluble, water insoluble; crosses placenta.> Should be administered orally or i.v. as i.v. route is slow, incomplete... | Anaesthesia | Miscellaneous | [
"chlorpromazine",
"diazepam"
] | 49,550 |
c1fc3549-62b2-479b-95f5-1b96fe2cd5a8 | Which of the following is most likely to be used in a young child with chronic renal insufficiency? | Cyanocobalamin | Desferrioxamine | Erythropoietin | Filgrastim (G-CSF) | 2c | single | Erythropoietin is produced by kidneys, in CRF production of erythropoietin is reduced and we need to supplement it from outside. Preprations used in CRF are Epoietin, Darbopoietin, Peginesatide. Its also used in anaemia due to myelosuppressive Drugs(zidovudine)and cancer chemotherapy. Cyanocobalamine is used in treatme... | Pharmacology | Hematology | [
"erythropoietin"
] | 49,558 |
8721015a-52df-4f7c-94ac-adb513fe2c24 | Beta blocker with membrane stabilizing propey are all except ? | Acebutolol | Betaxolol | Carvedilol | Bevantolol | 3d | multi | Ans. is 'd' i.e., Bevantolol | Pharmacology | null | [
"acebutolol",
"carvedilol"
] | 49,562 |
ca55caf4-d18e-4a37-8c53-48f340334994 | OCP's are C/I in pts receiving: | Rifampicin | Ethambutol | Streptomycin | Pyrazinamide | 0a | single | null | Gynaecology & Obstetrics | null | [
"ethambutol"
] | 49,566 |
c303caf7-3503-4c9d-839b-05aa0a62c4bc | Which among the following anti-HIV drugs is an inhibitor of viral fusion? | Enfuvirtide | Nelfinavir | Efavirenz | Etanercept | 0a | single | null | Pharmacology | null | [
"etanercept",
"nelfinavir",
"efavirenz"
] | 49,574 |
c1ec8fe8-e380-41d5-9f6c-2f1d26918c53 | There has been an outbreak of infections caused by methicillin resistant Staphylococcus aureus in the surgical intensive care unit. The most effective means of limiting the spread is - | Treatment with cephalosporins to which most strains are sensitive | Treatment with naficillin and gentamicin, which have a synergistic effect | Use of high-dose naficillin alone and isolation | Treatment with glycopeptide | 3d | single | null | Medicine | null | [
"gentamicin"
] | 49,594 |
98e69aa6-af36-4949-8f3c-4f46aa00e548 | Drug of choice in delirium tremens is | CPZ | Phenytoin | Chlordiazepoxide | Morphine | 2c | single | The drugs of choice for alcoholic detoxification are usually benzodiazepines. Chlordiazepoxide (80-200 mg/day in divided doses) and diazepam (40-80 mg/day in divided doses) are the most frequently used benzodiazepines. The higher limit of the normal dose range is used in delirium tremens. Ref: A Sho Textbook of Psychia... | Psychiatry | Substance abuse | [
"morphine",
"chlordiazepoxide",
"phenytoin"
] | 49,596 |
f9b5c9c8-4d50-4638-a4f9-3e8530a3cd9b | Sumatriptan is | 5-HT 1D/1B agonists | 5-HT 1D/1B antagonist | 5-HT 1A agonist, | 5-HT 1A antagonist | 0a | single | Sumatriptan a 5-HT 1D/1B agonist is used for acute migraine attacks. Buspirone, a 5-HT 1A agonist is an effective nonbenzodiazepine anxiolytic. ref - harrisons internal medicine 20e pg3100 | Medicine | C.N.S | [
"sumatriptan"
] | 49,597 |
586d7603-94e2-4d51-992e-ef0425c29277 | Diabetes insipidus treatment includes all EXCEPT: | Metformin | Chlorpropamide | Desmopressin | Carbamazepine | 0a | multi | (A) Metformin # Desmopressin: Desmopressin acetate is the treatment of choice for central diabetes in insipidus associated with pregnancy or the puerperium, since desmopressin is resistant to degradation by the circulating vasopressinase> It is usually given intranasally (100 pg./mL solution) every 12-24 hours as neede... | Medicine | Miscellaneous | [
"desmopressin",
"metformin",
"carbamazepine",
"chlorpropamide"
] | 49,600 |
6b6a22e2-ef59-4d14-b527-d662c4eb6f6a | Insulin secretion increasing drug by acting on beta cells of pancreas is - | Rapaglinide | Metformin | Poiglitazone | Acarbose | 0a | single | Ans. is 'a' i.e., Rapaglinide Oral hypoglycemic drugs may be divided into two groups. 1. Group 1 These drugs reduce plasma glucose by stimulating insulin production, therefore called insulin secretogogues. Hypoglycemia is a well known side effect. Examples are: i) Sulfonylureas: first generation (chlorpropamide, tobuta... | Pharmacology | null | [
"metformin",
"acarbose"
] | 49,623 |
481214ac-f5dc-4e75-b333-652ad6ca47c1 | Verapamil is associated with all of the following except ? | Constipation | Bradycardia | Hyperglycemia | Increased PR interval | 2c | multi | null | Pharmacology | null | [
"verapamil"
] | 49,627 |
f8a62f00-ffcf-46f2-bd43-4b42d4e4eb00 | Treatment of choice for lichen planus ? | Topical coicosteroids | Systemic coicosteroids | Antihistaminics | Acitretin | 0a | single | Ans. is 'a' i.e., Topical coicosteroids Treatment of Lichen planus The first line treatment of lichen planus are topical coicosteroids. Second choice would be systemic coicosteroids for symptom control and possibly more rapid resolution. Oral antihistaminics are given for pruritic. PUVA can be used for extensive lesion... | Skin | null | [
"acitretin"
] | 49,629 |
be267362-2a3d-4582-9d34-74c5ecc7d5ff | A 70 year old male patient presented to the emergency depament with pain in epigastrium and difficulty in breathing for 6 hours. On examination, his hea rate was chest examination was normal. The patient has been taking omeprazole for gastresophageal reflux disease for last 6 months. What should be the intial investiga... | An ECG | An upper GI endoscopy | Urgent ultrasound of the abdomen | An x-ray chest | 0a | single | Answer is A (An ECG) The patient in question may well be suffering from an acute myocardial infarction. An ECG to exculde an acute MI should be the initial Investigation. `Presence of Epigastric pain in association with breathlessness and evidence of parasympathetic overactivity (bradycardia and hypotension) suggests t... | Medicine | null | [
"omeprazole"
] | 49,637 |
aa2dcc50-96ee-4442-bbee-a09de2dfbc77 | True statement/ s regarding sevoflurane are all except | Ideal agent for pediatric anaesthesia | Can interact with sodalime and forms compound A | Can be used safely in malignant hyperpyrexia | Causes tachycardia | 2c | multi | All potent inhalational agents are contraindicated in malignant hypehermia. It has sweet smell so very useful in pediatrics for induction. Sevoflurane reacts with strong bases like sodium hydroxide and potassium hydroxide present in soda lime and baralyme leading to the formation of a haloalkene (fluoromethyl-2,2-diflu... | Anaesthesia | Inhalational Anesthetic Agents | [
"sevoflurane"
] | 49,668 |
7a5792e2-4dce-4b5a-a27d-daf579a1530a | Physiologically most active form of Vitamin D is | Calciferol | Calcitriol | Ergocalciferol | Cholecalciferol | 1b | multi | null | Social & Preventive Medicine | null | [
"calcitriol",
"ergocalciferol"
] | 49,677 |
722e561e-58f7-4150-ac13-b5a34563e03e | 3 ml of LA solution contains 2% lignocaine with 1:100000 epinephrine how many milligrams of each are present in the solution? | 6mg lidocaine, 0.3mg epinephrine | 60 mg lidocaine, 0.03 mg epinephrine | 6 mg lidocaine, 0.03 mg epinephrine | 600 mg lidocaine, 0.3 mg epinephrine | 1b | single | Learn the following facts, and you can solve all numerical of LA.
% (per cent--'cent' means 100) means g/100ml, so 2% lignocaine means 2g/100ml, or 2000mg/100ml of solution = 20mg/ml.
1 cartridge contains around 2 ml solution.
Thus, 3 ml contains 60mg lidocaine.
1 in 1 lakh adrenaline means 1g in 1 lakh ml or 10... | Surgery | null | [
"epinephrine",
"lidocaine"
] | 49,679 |
7cd71d0e-e5ea-48a4-bd2c-0ae2e7390c0e | A fungicidal drug that can be used orally for the treatment of onychomycosis is: | Griseofulvin | Amphotericin B | Clotrimazole | Terbinafine | 3d | multi | Fungicidal drugs are amphotericin B and terbinafine. Out of these, amphotericin B cannot be given orally. Thus, the answer is terbinafine. | Pharmacology | Anti-Fungal Drugs | [
"clotrimazole",
"terbinafine",
"griseofulvin"
] | 49,680 |
dfcc91d2-653b-4105-bdcb-b939834a8f49 | Most emetogenic drug is aEUR' | Cisplatin | Carboplatin | High dose cyclophosphamide | High dose methotrexate | 0a | single | Cisplatin; 'c' i.e., High dose cyclophosphamide The most common side effect of chemotherapy administration is nausea and vomiting. Antineoplastic agents may vary in their capacity to cause nausea and vomiting. | Pharmacology | null | [
"carboplatin",
"methotrexate",
"cyclophosphamide",
"cisplatin"
] | 49,685 |
bb29cb43-a91e-486a-9a0b-a530a18a3208 | Which of the following antiepileptic is also a free radical scavenger? | Levetiracetam | Topiramate | Zonisamide | Gabapentin | 2c | single | Zonisamide is a Na+ channel blocker & also a free radical scavenger. | Pharmacology | null | [
"zonisamide",
"topiramate",
"gabapentin"
] | 49,693 |
c5dff84a-ae1f-41b8-aabf-2e5a9ded6dcd | Therapeutic level of phenytoin is: | 0-9 mu g/ml | 10-19 mu g/ml | 20-29 mu g/ml | 30-39 mu g/ml | 1b | single | Ref: Katzung 11/e p404 The therapeutic level of phenytoin is 10-20 micro g/ml. | Pharmacology | Central Nervous system | [
"phenytoin"
] | 49,695 |
db423e02-c694-43ac-a813-edf44c44fb00 | Digoxin is useful in - | Atrial fibrillation in thyrotoxicosis | Complete hea-block with CHF | Ventricular tachycardia | Myocarditis | 1b | single | Ans. is 'b' i.e., Complete hea-block with CHF Digitalis has depressant action on AV node -4 it delayes the conduction through AV node by increased ERP. If paial block is present, digitals may conve it into complete block. But, if complete block is already present, digitalis cannot worsen the condition (as conduction is... | Pharmacology | null | [
"digoxin"
] | 49,696 |
ea7c2283-12ac-43fc-a350-5031be31dd79 | Receptors are located in the nucleus for all the following except | Insulin | Vitamin D | Thyroxine | Vitamin A | 0a | multi | Insulin receptors are enzyme-linked tyrosine kinase receptors on cell surface. nuclear or cytosolic receptors include steroid hormone,vit A, vit D, thyroid hormones Ref: HL Sharma 3rd ed Pg 66 | Pharmacology | General pharmacology | [
"thyroxine"
] | 49,738 |
9188da13-58d7-43af-8798-71188571e982 | Which of the following neurotransmitter is MOST impoant for the induction of REM sleep? | Acetylcholine | Dopamine | Epinephrine | Norepinephrine | 0a | single | Acetylcholine is the neurotransmitter of primary impoance for the induction of REM sleep. Some of the other neurotransmitters do function in sleep, but REM sleep can occur in their absence. Dopamine is a neurotransmitter with a role in voluntary movement, mood, cognition, and regulation of prolactin release. Epinephrin... | Physiology | null | [
"epinephrine"
] | 49,798 |
7699073c-5125-42ca-b7d7-6003ef55840b | Relaxation of mesangial cells of kidney is brought about by ? | cAMP | Endothelin | PGF2 | Vasopressin | 0a | single | A i.e. C-Amp | Physiology | null | [
"vasopressin"
] | 49,845 |
a252fd6c-1926-4188-bd46-444bbd3cfc0e | Least toxic organiophosphorus compound is - | DDT | Paris green | Malathion | Parathion | 2c | single | Malathion has the least toxicity of all organophosphorus compounds. Yellow/clear brown liquid used in dose of 100-200 mg.per.sq.ft. every 3 months because of its low toxicity, malathion has been recommended as an alternative insecticide to DDT. as a low volume spray (ULV) spray it has been widely used to kill adult mos... | Social & Preventive Medicine | Environment and health | [
"malathion"
] | 49,853 |
d81d4529-76c2-4874-ac65-b9d600a47db7 | Drugs used in emergency contraception are all except : | Levonorgestrel | Estrogen + progesterone | Danazol | Mifepristone | 2c | multi | Danazol is not used as an emergency contraceptive. It is used in the medical treatment of endometriosis. OXFORD HANDBOOK OF OBSTETRICS AND GYNAECOLOGY THIRD EDITION PAGE NO 587 | Gynaecology & Obstetrics | Contraception | [
"danazol",
"mifepristone"
] | 49,858 |
4f7fcb3e-9985-4d0c-9269-ec2b362c4aa1 | Not true regarding atropine | Used as an eye ointment | Used in refraction in less than 5 yr of children | Fast action | Experimentally used in treatment of myopia | 2c | multi | Atropine is slow acting and not fast acting ATROPINE( antimuscranic) causes cycloplegia as ciliary muscles are supplied by Parasympthetic sytem sho ciliary nerve , branch of 3rd cranial nerve Used as eye ointment Children < 5 yr, Children with Squint slow action Three times for 3 days Peak Effect- 3 Days Complete cyclo... | Ophthalmology | Optics and Errors of Refraction | [
"atropine"
] | 49,872 |
fb20aad4-6d70-4df5-a709-9ea14d0d5fe8 | Which of the following is the most potent H2 blocker used in peptic ulcer disease | Cimetidine | Famotidine | Ranitidine | Nizatidine | 1b | single | Famotidine is the most potent H2 blocker. | Pharmacology | null | [
"cimetidine",
"ranitidine",
"famotidine"
] | 49,875 |
0c1200c7-dba3-40f4-a5d6-af03e75e26c5 | A 32yr old patient came to the Gyne. OPD with complains of bleeding per vaginum . Bleeding was for a prolonged period of time than her usual number of days in her regular menses. There was no significant finding on examination. On fuher examination, she told that she was on warfarin therapy for past 1 yr. And also told... | Clarithromycin | Sulphonamide | Ciprofloxacin | Carbamazepine | 3d | single | These are those drugs which inhibit cyt 450 and increase the half life of warfarin resulting in increased bleeding.sulphonamides don't allow degradation of warfarin : Increased bleeding, but carbamazepine is enzyme inducer and hence not responsible for the condition and decreases the half life of warfarin leading to de... | Pharmacology | Pharmacokinetics | [
"ciprofloxacin",
"clarithromycin",
"carbamazepine",
"warfarin"
] | 49,881 |
fa7c8e37-26ac-4e8e-baa6-0478f4bc328d | All of the following are true regarding sumatriptan except: September 2009 | 99% oral bioavailability | Contraindicated in coronary aery disease | Constricts cranial vessels | Selective 5-HT 1B/1D receptor agonist | 0a | multi | Ans. A: 99% oral bioavailability Sumatriptan is structurally similar to serotonin, and is a selective 5-HT 1B/1D receptor agonist. The specific receptor subtypes it activates are present on the cranial aeries and veins. Acting as an agonist at these receptors, Sumatriptan reduces the vascular inflammation associated wi... | Pharmacology | null | [
"sumatriptan"
] | 49,893 |
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