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|---|---|---|---|---|---|---|---|---|---|---|---|---|
b5dfa3c3-c841-4c76-a771-87ba597a77a6 | All are adulterants of heroin, except: | Chalk powder | Quinine | Charcoal | Fructose | 2c | multi | C i.e Charcoal Morphine depress respiratory centre, so rate & tidal volume both are decreasedQ & death is due to respiratory failure. YawningQ, dysphoric mood & insomnia with water loss from different orifices (i.e. lacrymation, sweating, diarrhoea, vomiting, rhinorrhea) are characteristic symptoms of opioid withdrawl ... | Forensic Medicine | null | [
"quinine"
] | 51,140 |
a089b3a5-70d5-4257-9f69-d31f916ca709 | True about tamoxifen is- | Selective estrogen receptor downregulator | Selective estrogen receptor modulator | Selective tissue estrogen activator regulator | Estrogen antagonist | 1b | multi | Ans. is 'b' i.e., SERM * Has been explained in previous sessions | Pharmacology | Endocrinology | [
"tamoxifen"
] | 51,141 |
1d69169b-38f9-49eb-b237-f7ffa6f9dabb | Transaerial chemoembolization (TACE) is used in the treatment of unresectable hepatocellular carcinoma without poal vein thrombosis. The drug commonly used for TACE is: | Doxorubicin | Sorafenib | Tamoxifen | Carboplatin | 0a | single | There are different treatment modalities for HCC. Curative treatments are resection, liver transplantation, Radiofrequency ablation (RFA), Percutaneous ethanol injection etc. Palliative treatments are TACE, Sorafenib etc. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Cha in Page 781. | Medicine | null | [
"tamoxifen",
"carboplatin",
"doxorubicin"
] | 51,146 |
52411363-8333-4571-8ab2-4872d5fbd235 | Resuscitation of a child with HR<60/min includes all of the following, except | Chest compression | Adrenaline | Endrotracheal tube intubation | Never give atropine | 3d | multi | Ref. The Short Textbook of Pediatrics. Pg 271
Atropine is considered when there is a AV block | Unknown | null | [
"atropine"
] | 51,147 |
540b6a57-ac39-4d03-b2ed-12c7bc3d4d61 | Presence of trifluroacetic acid (TFA) in urine indicates that volatile anaesthetic agent used was | Halothane | Methoxyflurane | Trichloroethylene | None of the above | 0a | multi | Ans. is 'a' i.e., Halothane | Surgery | null | [
"methoxyflurane",
"halothane"
] | 51,155 |
230158d2-3358-44dd-84b9-522a4e5b2323 | Site of action of vecuronium is? | Cerebrum | Reticular formation | Motor neuron | Neuro-muscular junction | 3d | single | Ans. is 'd' i.e., Neuro-muscular junction* Vecuronium, a non-depolarizing blocker, acts on nicotinic receptors at myoneural junction.* Neuro-muscular blocker act at myoneural junction1. Competitive (Non-depolarizing) blocker: -# They compete with Achfor Nm receptors - called competitive blockers. They prevent binding o... | Anaesthesia | Muscle Relaxant | [
"vecuronium"
] | 51,171 |
572a90dd-f1bc-45d9-a2bf-53d8dd7f58a8 | In treatment of Osteosarcoma all of the following are used except (REPEAT) | High dose Methotrexate | Cycloohosphamide | Vincristine | Doxorubicin | 2c | multi | Though surgery is the form of primary treatment in Osteosarcoma but etoposide cycloohosphamide, Cisplatin, Doxorubicin have been used High dose Methotrexate has been the drug of choice and is the only FDA approved agent for this condition Ref Katzung 10th/891 | Pharmacology | Chemotherapy | [
"methotrexate",
"vincristine",
"doxorubicin"
] | 51,179 |
dce86bb6-0ff4-45b0-8d61-e30f2b17cb44 | Which of the following is not conveed into active metabolite | Lisinopril | Fluxotine | Cyclophosphamide | Diazepam | 0a | single | all ACE inhibitor are prodrug except captopril and lisinopril drug -active metabolite fluxotine-non fluxotine Cyclophosphamide- adenophosphamide Diazepam-oxazepam Refer KDT 7/e p22 -23 | Anatomy | General anatomy | [
"lisinopril",
"cyclophosphamide",
"diazepam"
] | 51,184 |
407b777e-b8f5-4c3c-b7e3-a95896225948 | Drug of choice for ventricular arrhythmia due to myocardial infarction is | Quinidine | Amiodarone | Xylocaine | Diphenylhydantoin | 2c | single | Refer kDT 6/e p 519 Drug of choice for ventricular arrhythmias with myocardial infarction is lignocaine Drug of choice for supraventricular arrhythmia after myocardial infection is beta blockers cardiac function is adequate | Pharmacology | Cardiovascular system | [
"amiodarone",
"xylocaine",
"quinidine"
] | 51,203 |
e225e13d-0396-47db-958e-43a5ad7c3c75 | The production of cervical mucus is stimulated by : | Progesterone | Estradiol | Estriol | Pregnenolone | 1b | single | Cervical mucus is a glycoprotein gel that expand and contract in response to cyclic changes in the steroid hormone environment across the menstrual cycle to facilitate or inhibit the passage of sperms. Estrogen stimulates cervical mucus production, and as levels rise during the follicular phase, mucus becomes more abun... | Gynaecology & Obstetrics | Reproductive physiology and hormones in females | [
"estriol"
] | 51,215 |
81bce5ef-7c7a-4307-ac5b-1b1a65201a47 | Which of the following antibiotic does not act by inhibiting protein synthesis ? | Vancomycin | Tetracycline | Streptomycin | Azithromycin | 0a | single | null | Pharmacology | null | [
"azithromycin",
"tetracycline",
"vancomycin"
] | 51,249 |
613b20fa-4770-4b74-8147-1486c0eabd60 | Which of the following drugs can cause galactorrhea? | Omeprazole | Metoclopramide | Bromocriptine | Ranitidine | 1b | single | Galactorrhea is caused by prolactin secretion. Dopamine normally inhibits the secretion of prolactin. Thus dopamine antagonists can cause hyperprolactinemia leading to galactorrhea. The drugs include: Typical Antipsychotics like Haloperidol Antiemetics like Metoclopramide Dopamine depleter like Reserpine. Drugs stimula... | Pharmacology | Pituitary-Hypothalmic System and Thyroid | [
"metoclopramide",
"bromocriptine",
"ranitidine",
"omeprazole"
] | 51,259 |
ffe1a875-2f3a-4280-9b43-5e5fc9927ec3 | Preferred fluid in a poly-traumatic patient with shock? | Ringer lactate | Normal saline | Dextran | Dextrose-normal saline | 1b | single | Ans. (b) Normal salineRef.-.Harrison 18th ed. / 270Normal saline is the preferred fluid for volume expansion in a crashing patient with un-recordable BP. The main point to be noted is that if ringer lactate is infused in these patients, then lactate in the solution will never reach the liver where it is normally conver... | Surgery | Miscellaneous (Fluid & Electrolyte) | [
"dextran"
] | 51,271 |
80d90d08-f819-4195-90f0-05a3d0545643 | Catalase positive novobiocin resistant bacteria is: | Staphylococcus aureus | Staphylococcus epidermidis | Staphylococcus saprophyticus | None of the above | 2c | multi | Ans. is 'c' i.e., Staphylococcus saprophyticus(Ref: Ananthanarayan, 9th/e, p. 202)* All staphylococcus are catalase positive.* Staphylococcus saprophyticus is resistant to novobiocin. | Microbiology | Bacteria | [
"novobiocin"
] | 51,283 |
a9e4d73d-869e-47df-8039-19f88b29cdfa | All of the following agents are used in the treatment of hot flashes, EXCEPT: | Tamoxifen | Venlafaxine | Gabapentin | Paroxetine | 0a | multi | Tamoxifen is a selective estrogen receptor modulator (SERM) which exhibits anti-estrogenic activity on tissues like breast and central nervous system and estrogenic activity on tissues like bone. Tamoxifen produces hot flashes and other adverse effects, including cataracts and nausea . The other three options - Venlafa... | Gynaecology & Obstetrics | null | [
"gabapentin",
"tamoxifen",
"paroxetine"
] | 51,330 |
4ad0838e-4aec-4723-9c44-a152a743ab92 | Which of the following barbiturate is used for induction? | Thiopentone | Naloxone | Naltrexone | Phenobarbitone | 0a | single | Ans: a (Thiopentone) Ref: KDT, 6th ed,p. 374* Thiopentone sodium is an ultrashortacting thiobarbiturate highly soluble in water, yielding a very alkaline solution (pH 10.4)* On IV injection it produces loss of consciousness in one arm- brain circulation time * Ultrashort duration of thiopentone is because of methyl gro... | Anaesthesia | General Anesthesia | [
"naloxone",
"naltrexone"
] | 51,332 |
e5e7854d-3d62-4512-be2e-1a7e559f1c01 | Pilocarpine is not used in young adults as it causes: | Retinal detachment | Myopia | Iris cysts | Shallow anterior chamber | 1b | multi | Ans. (b) MyopiaRef: Khurana 6/e, p. 449; Kanski 7/e; p. 386Contraction of ciliary muscle results in accommodation and thus also cause transient, fluctuating myopia. | Ophthalmology | Glaucoma | [
"pilocarpine"
] | 51,353 |
a3ec7e91-5048-4de9-8b06-d6e9ca551fe1 | Maximum analgesic action found in – | Catecholamine | Propofol | Ketamine | Thiopentone | 2c | single | Ketamine is different from most other anaesthetic induction agents in that it has significant analgesic action. | Anaesthesia | null | [
"ketamine",
"propofol"
] | 51,357 |
df6b1d88-d71d-410d-a38f-7e1934629338 | Malignant hypehermia is a rare complication of the use of the following anaesthetic: | Ketamine | Thiopentone sodium | Halothane | Ether | 2c | single | Rarely, Halothane can cause Malignant hypehermia, which is treated with dantrolene Inhalational anesthetic agents and Depolarising NM blockers like succinylcholine can precipitate malignant hypehermia. | Pharmacology | Anaesthesia | [
"ketamine",
"halothane"
] | 51,360 |
0ba3932a-a8be-484c-809f-7e72fa31b880 | A 30-year old female complains of lower abdominal pain and purulent vaginal discharge. Her pulse rate is 98/min, temperature is 101oF, WBC and ESR are raised. Per vaginal examination reveals lower abdominal tenderness and cervical motion tenderness. What is the best treatment option for her? | Single IM injection of Ceftriaxone with oral doxycycline and oral metronidazole for 14 days | Single dose of Ceftriaxone injection with oral Azithromycin for 14 days | Oral Metranidazole for 14 days | Oral Oflaxacin and oral Metronidazole for 14 days | 0a | multi | The best treatment is single IM injection of Ceftrixone with oral Doxycycline and oral metronidazole for 14 days. The diagnosis is pelvic inflammatory disease. Sexually transmitted organisms especially N.gonorrhoeae and C.trachomatis are implicated in many cases. The best treatment for OPD management of PID is: Inj. Ce... | Gynaecology & Obstetrics | Infections of the genital tract | [
"metronidazole",
"azithromycin",
"doxycycline",
"ceftriaxone"
] | 51,362 |
1c2213b8-bcd6-4a50-9afd-c95e1d5c74de | Best anaesthetic drug to be given in day care surgery: | Ketamine | Sevoflurane | Desflurane | Propofol | 3d | single | Ans. (d) PropofolRef: KDT 6th ed./373-374PROPOFOL* Anesthesia of choice for day care surgery.* Short acting, action diminishes the same day.* Advantage: has anti emetic property. It is safe in porphyria.* Disadv: Causes myocardial depression and hypotension. | Anaesthesia | Miscellaneous General Anesthesia | [
"ketamine",
"sevoflurane",
"desflurane",
"propofol"
] | 51,366 |
42fcf2f0-f933-49fd-8d67-602b988d3b2e | Main MOA brimonidine in glaucoma - | Decreased aqueous secretion | Increased trabecular outflow | Increased uveoscleral outflow | Reduce vitreous volume | 0a | single | Brimonidine (0.2% : 2 times/day). It is a selective alpha-2-adrenergic agonist and lowers IOP by decreasing aqueous production. Because of increased allergic reactions and tachyphylaxis rates it is not considered the drug of first choice in POAG. It is used as second drug of choice and also for combination therapy with... | Ophthalmology | Glaucoma | [
"brimonidine"
] | 51,381 |
83e5e391-180a-425f-8b7a-3b864b2b5ca0 | Mucormycosis -a) Angio-invasionb) Lymph invasionc) Septate hyphaed) Long term deferoxamine therapy is predisposing factore) It may lead to blindness | acd | ade | abd | ad | 1b | single | null | Microbiology | null | [
"deferoxamine"
] | 51,383 |
8a77376c-51e4-4c2e-946f-720572390f1f | Drug of choice as antidiabetic in obese patient: | Glipizide | Insulin | Tolbutamide | Metformin | 3d | single | Ans. D. MetforminMetformin is the first line treatment in case obese diabetic patient as it is known to cause weight loss. It doesn't cause the release of insulin and thus less chances of hypoglycemia. | Pharmacology | Endocrinology | [
"glipizide",
"metformin",
"tolbutamide"
] | 51,389 |
70aa145c-cb91-40ed-b04b-73ffda9b3785 | Mitosis is arrested in ________ phase by using colchicine in cytogenetic analysis. | Prophase | Metaphase | Anaphase | Telophase | 1b | single | null | Medicine | null | [
"colchicine"
] | 51,390 |
27cf10ee-16ce-4c86-b739-15f380471e95 | All of the following causes increase in heart rate except: | Halothane | Isoflurane | Sevoflurane | Desflurane | 0a | multi | null | Pharmacology | null | [
"sevoflurane",
"desflurane",
"isoflurane",
"halothane"
] | 51,402 |
b950ee35-8a68-4f91-b2d1-a803352fcc4f | Side effects of Pilocarpine are A/E – | Shallow anterior chamber | Punctate stenosis | Follicular conjunctivitis | Posterior synechia | 1b | multi | Most guides have given option a as the answer.
I have done extensive search on this. First you see the topical adverse effects of parasympathomimetic antiglaucoma drugs (from yanoff & Duker) :-
Directly acting (cholinergic agonists like pilocarpine, carbachol) → Miosis, uveitis, browache, cataracts, myopia, retinal de... | Ophthalmology | null | [
"pilocarpine"
] | 51,405 |
aa69e4c6-2f9c-45dd-b7d1-5ff7cdd2dee0 | Select the antibiotic most frequently associated with the Hypoplasia and staining of fetal teeth (SELECT 1 ANTIBIOTIC) | Tetracycline | Streptomycin | Nitrofurantoin | Chloramphenicol | 0a | single | Fetal exposure to an antibiotic depends on many factors such as gestational age, protein binding, lipid solubility, pH, molecular weight, degree of ionization, and concentration gradient. Some antibiotics are even concentrated in the fetal compartment. Tetracycline is contraindicated in all three trimesters. It has bee... | Gynaecology & Obstetrics | Fetus & New Born and their Diseases | [
"tetracycline",
"chloramphenicol",
"nitrofurantoin"
] | 51,412 |
1075b481-d491-4c4f-94fe-48d97d1a59b0 | Drug of choice for MRSA skin infection is | Streptogramin | Vancomycin | Quinupristin | Linezolid | 1b | single | (B) Vancomycin # Drugs used in the treatment of MRSA: Vancomycin, Linezolid, Teicoplanin, Cotrimoxazole, Oxacillin, RifampicinTREATMENT OF COMMON INFECTIONS OF THE SKINDiagnosis/ConditionPrimary TreatmentAlternative TreatmentAnimal bite (prophylaxis or early infection)Amoxicillin/clavulanate, 875/125 mg PO bidDoxycycli... | Medicine | Miscellaneous | [
"linezolid",
"vancomycin"
] | 51,416 |
74b64e24-b9b1-4796-b918-d9ff2d840fff | Treatment for Pityriasis versicolor includes? | Griesofiilvin | Terbinafine | Itraconazole | All of the above | 2c | multi | Ans. is 'c' i.e., Itraconazole 'Adequate treatment with itraconazole can be achieved with a total dose of as little as 1000mg, given as 200mg per day for 5-7 days." - IADVL 3rd/e p. 288* Selenium sulphide (2.5%) in detergent base is applied all over body below neck (sparing the genitalia), left overnight and washed of ... | Skin | Fungal Infection | [
"itraconazole",
"terbinafine"
] | 51,431 |
fc36d1d4-b62d-46f2-b1be-f7f4f2e6adfd | Which antibiotic acts by inhibiting protein synthesis - | Cefotetan | Doxycycline | Ciprofloxacin | Oxacillin | 1b | single | Ans. is 'b' i.e., Doxycycline | Pharmacology | null | [
"cefotetan",
"ciprofloxacin",
"doxycycline"
] | 51,441 |
da5a4975-1338-4395-a177-b880fcfd103a | A 28 year old male presented with rash on his arms, legs and face, and painful ulceration of his lips and mouth along with fever. He developed an acute sore throat and conjunctivitis, following which a diagnosis of acute pharyngitis was made, presumed streptococcal, and oral penicillin was prescribed. All of the follow... | Cyclophosphamide | IVIg | Cyclosporine | Etanercept | 0a | multi | This is a case of Steven Johnson syndrome with the classical targetoid lesions. In Stevens- Johnson syndrome, lesions involve not only the skin but also the lips and oral mucosa, conjunctiva, urethra, and genital and perianal areas. On histologic examination, the "targetoid" lesions show a superficial perivascular, lym... | Unknown | Integrated QBank | [
"etanercept",
"cyclophosphamide",
"cyclosporine"
] | 51,450 |
20725f98-fab9-4671-8bf2-37e6116b039b | All of the following agents are used in the treatment of alcohol dependence except: | Flumazenil | Acamprosate | Naltrexone | Disulfiram | 0a | multi | Flumazenil (Benzodiazepine receptor antagonist) --> It is used in benzodiazepine overdose. Disulfiram- Aversive agents Acamprosate- Anticraving agent Naltrexone- Anticraving agent | Psychiatry | Substance Related and Addictive Disorders | [
"disulfiram",
"flumazenil",
"naltrexone"
] | 51,452 |
8f47cd58-8656-4b51-82df-4cdf28a33d03 | A 10 years boy presented with Cola coloured urine, oliguria for 3 days, facial puffiness, edema and hypeension. Urine albumin is positive and C3 levels are reduced. BP is 130/80. He had skin infection two weeks back. Which of the following is true about this condition? | Renal biopsy is required in all cases | C3 levels return to normal in 6-8 weeks | Cyclosporine is the treatment of choice | Most common age group involved is 1-4 years | 1b | multi | The given clinical picture suggests a diagnosis of nephritic syndrome, most probably post-streptococcal glomerulonephritis (PSGN). Poststreptococcal glomerulonephritis (PSGN) is a classic example of the acute nephritic syndrome characterized by the sudden onset of gross hematuria, edema, hypeension, and renal insuffici... | Pediatrics | Nephritic & Nephrotic Syndrome | [
"cyclosporine"
] | 51,458 |
8ea0b3d1-8a63-4b1a-b91e-109daf355576 | Depression in elderly is treated with? | Imipramine | Dothiepin | Fluoxetine | Mianserine | 2c | single | Ans. c. Fluoxetine. (Ref. Psychiatry by Niraj Ahuja, 5th ed., 78)Newer anti-depressants like SSRI (fluxetine, sertraline, citalopram, mitrazepam, and venlafexine) have very little cholinergic effects, side effects and hence safer drugs to use in elderly, especially with heart diseases and BMP. Educational points: Grief... | Psychiatry | Mood Disorders | [
"fluoxetine",
"imipramine"
] | 51,480 |
237f8403-4861-4b0c-bb4e-fcaab70bf3b2 | Which of these drugs DO NOT decrease angiotensin Il activity | Enalapril | Valsaan | Nesiritide | Omapatrilat | 2c | single | (Ref: Katzung 10/e p205, 286) ACE inhibitors and AT1, antagonists decrease angiotensin Il activity. Omapatrilat is a vasopeptidase inhibitor that acts by inhibiting two enzymes, ACE and NEP. As it inhibits ACE, it may also decrease angitotensin II activity. Nesiritide is a recombinant BNP and has no effect on angiotens... | Anatomy | Other topics and Adverse effects | [
"nesiritide",
"enalapril"
] | 51,490 |
9e9f8511-c62c-447f-8175-6a6b4b062b8c | Cause of metabolic alkalosis includes | Furosemide | Addision disease | Hyperkalemia | Hyponatremia | 0a | single | Causes of Metabolic Alkalosis I. Exogenous HCO3-loads A. Acute alkali administration B. Milk-alkali syndrome II. Effective ECFV contraction, normotension, K+ deficiency, and secondary hyperreninemic hyperaldosteronism A. Gastrointestinal origin 1. Vomiting 2. Gastric aspiration 3. Congenital chloridorrhea 4. Villous ad... | Medicine | Fluid and electrolytes | [
"furosemide"
] | 51,492 |
f5c1edcd-44e5-43ae-b578-4e7571c6c83c | Which of the following drugs cannot be used in patient with Multi drug resistant Tuberculosis? | Ciprofloxacin | Tobramycin | Clarithromycin | Amikacin | 1b | single | It is aminoglycoside group of drug used in various bacterial infection, paiculary gram negative. It extes its action by inhibiting on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. It is not used as antimycobacterial. Other aminoglycosides such as streptomycin and amikacin are used as anti... | Pharmacology | null | [
"amikacin",
"clarithromycin",
"ciprofloxacin"
] | 51,501 |
78677219-0a75-4535-920c-52a9ca05e4de | Veical transmission of resistance to ciprofloxacin occurs :- | Transduction | Transformation | Conjugation | Mutation | 3d | single | Ciprofloxacin: Veical transmission -from parents to progeny (daughter cells) among bacterial cells Horizontal transmission - from one bacteria to another bacteria simultaneously Veical transmission is mainly by mutation Horizontal transmission is mainly by various methods Transduction Transformation Conjugation | Pharmacology | FMGE 2017 | [
"ciprofloxacin"
] | 51,508 |
a349488b-a294-430c-932e-2f43f89b03ca | The following antibiotic accentuates the neuromuscular blockade produced by pancuronium : | Streptomycin | Erythromycin | Penicillin G | Chloramphenicol | 0a | single | null | Pharmacology | null | [
"erythromycin",
"chloramphenicol",
"pancuronium"
] | 51,511 |
61953b92-4696-4cad-80a0-c135d25d97f6 | Nitroglycerin cause all except | Hypotention and bradycardia | Methamoglobinemia | Hypotention and tachycardia | Vasodilatation | 0a | multi | Refer katzung 11e p 265 KDT 6/e p524 Nitrates most commonly used antianginal drugs. These act by decreasing delivery of nitric oxide in the blood vessels leading to vasodilatation. | Pharmacology | Cardiovascular system | [
"nitroglycerin"
] | 51,520 |
38baef17-ee53-4ac3-bf8b-486713961ff9 | A patient admitted to an ICU is on a central venous line for the last one week. He is on ceftazidime and amikacin. After 7 days of antibiotics, he develops a spike of fever, and his blood culture is positive for gram-positive cocci in chains, which are catalase negative. Following this, vancomycin was staed, but the cu... | Coagulase- negative staphylococcus | Staphylococcus aureus | Enterococcus faecalis | Viridans streptococci | 2c | single | From the case scenario, the most likely organism involved is Enterococcus faecalis. The organism is described as gram positive cocci in chains, which are catalase negative. This helps rule out Staphylocococcus aureus and coagulase-negative Staphylococcus. Streptococcus viridians is usually sensitive to penicillin and v... | Microbiology | miscellaneous | [
"amikacin",
"ceftazidime",
"vancomycin"
] | 51,525 |
8c3401a0-3ac8-4cb4-b570-5f731bf6e040 | Oligospermia caused by- | Methotrexate | Hydroxychloroq uine | Leflunomide | D-penicillamine | 0a | single | Ans. is 'a' i.e., Methotrexate"Transient but reversible oligospermia has been repoed in males receiving high dose methotrexate for cancer chemotherapy".Defective oogenesis or spermatogenesis "Occurs in methotrexate therapy" | Pharmacology | null | [
"methotrexate",
"penicillamine"
] | 51,535 |
27d104d7-9c07-4a04-8980-bf7da5694f06 | A 43-year-old woman develops acute renal failure following an emergency resection of a leaking abdominal aortic aneurysm.Three days after surgery, the following laboratory values are obtained:* Serum electrolytes (mEq/L): Na+:127;K+:5.9;Cl-:92;HCO3-:15* Blood urea nitrogen: 82 mg/dL* Serum creatinine: 6.7 mg/dLThe pati... | 10% calcium gluconate, 10 mL | Digoxin, 0.25 mg every 3 h for three doses | Oral Kayexalate | Lidocaine, 100 mg | 0a | single | The electrocardiogram exhibited in the question demonstrates changes that are essentially diagnostic of severe hyperkalemia. Correct treatment for the affected patient includes administration of a source of calcium ions (which will immediately oppose the neuromuscular effect of potassium) and administration of sodium i... | Surgery | Wounds, Tissue Repair & Scars | [
"digoxin",
"lidocaine"
] | 51,550 |
782e618e-e369-4e1d-962d-ee4e8f8bc595 | A 72 year old woman presents with complaints of persistent urinary urgency, and incontinence. Her past medical history is significant for type 2 diabetes, for which she is currently taking glyburide, 5 mg twice daily. Which of the following is the most appropriate treatment for this patient? | Bumetanide | Metoprolol | Neostigmine | Oxybutynin | 3d | single | The patient is presenting with signs and symptoms of bladder instability. Oxybutynin both exes a direct antispasmodic effect and inhibits the muscarinic action of acetylcholine on smooth muscle. Although this agent exes approximately one fifth the anticholinergic activity of atropine, it has 4-10 times the antispasmodi... | Pharmacology | null | [
"oxybutynin",
"metoprolol",
"neostigmine"
] | 51,561 |
b316bc28-f75e-41db-9f24-ea31da08017d | A patient presents with nephrotic syndrome and hypoalbuminemia. Protein binding of which drug is not affected - | Tolbutamide | Morphine | Diazepam | Valproate | 1b | single | Ans. is 'b' i.e., Morphine in nephrotic syndrome there is no effect on protein binding. o Other three drugs are plasma protein bound drugs. | Pharmacology | null | [
"morphine",
"valproate",
"diazepam",
"tolbutamide"
] | 51,564 |
ba361f07-b0a5-4a3f-951e-1e9e3ba0d5ee | Propranolol is C/I in a patient of angina who is already receiving | Nifedipine | Aspirin | Verapamil | Isosorbide mononitrate | 2c | single | propranolol is a beta blocker and verapamil is a calcium channel blocker both given in combination can cause decrease in hea rate drastically hence contraindicated. Ref: KD Tripathi 8th ed. | Pharmacology | All India exam | [
"propranolol",
"nifedipine",
"verapamil",
"isosorbide"
] | 51,575 |
c9351352-d944-444b-9c7b-adea5c20d921 | Diplopia with ataxia are the adverse effects of which of the following drugs? | Phenytoin and carbamazepine | Gabapentin and carbamazepine | Gabapentin with phenytoin | Valproate and topiramate | 0a | single | Phenytoin ,Valproate and Carbamazepine causes ataxia with diplopia Topiramate mainly causes renal stones. So first option is better one. | Pharmacology | Epilepsy | [
"carbamazepine",
"valproate",
"gabapentin",
"phenytoin",
"topiramate"
] | 51,600 |
d74072b5-9c6d-4479-ac56-51443252f730 | At the end of a balanced anaesthesia technique with non-depolarizing muscle relaxant, a patient recovered spontaneously from the effect of muscle relaxant without any reversal. Which is the most probable relaxant the patient had received? | Pancuronium | Gallamine | Atracurium | Vecuronium | 2c | multi | This patient has received a non depolarizing muscle relaxant and has recovered spontaneously from its effect without any reversal, so he would have received atracurium. Atracurium is a sho acting muscle relaxant. It is inactivated spontaneously by nonenzymatic degradation (Hofmann elimination) in addition to that by ch... | Anaesthesia | null | [
"atracurium",
"vecuronium",
"pancuronium",
"gallamine"
] | 51,606 |
0552ea96-94c2-4a60-8dd8-2ccdbc030053 | Malignant hypehermia is most common with | Succinyl Choline | Gallamine | Dantrolene | Ketamine | 0a | multi | A i.e. Succinyl choline | Anaesthesia | null | [
"ketamine",
"dantrolene",
"gallamine"
] | 51,612 |
965d678a-e4bf-48b9-ac11-17cf72cb42bb | Treatment of acute phase of Kawasaki Disease is - | Aspirin | IV steroids | IV immunoglobins | Cyclophosphamide | 2c | single | Ans. is 'c' i.e., IV immunoglobins Kawasaki diseaseo Kawasaki disease, also known as lymph node syndrome, mucocutaneous-lymph node syndrome, and infant polyarteritis, is a poorly understood self-limited vasculitis that affects many organs, including the skin mucous membrane, lymph nodes, heart and blood vessel wallso I... | Pediatrics | Musculo Skeletal Disorders | [
"cyclophosphamide"
] | 51,619 |
d20291b2-55d8-4156-bcd8-af95761db95b | During rapid induction of anesthesia ? | Sellick's maneuver is not required | Pre-oxygenation is mandatory | Suxamethonium is contraindicated | Patient is mechanically ventilated before endotracheal intubation | 1b | multi | Ans. is 'b' i.e., Pre-oxygenation is mandatory During rapid sequence induction preoxygenation is done for full 3 minutes. Sch is the muscle relaxant of choice for intubation. Sallieck's maneuver is done to prevent aspiration. Manual ventilation before intubation is avoided as this inflates the stomach and encourages re... | Anaesthesia | null | [
"suxamethonium"
] | 51,621 |
c2db1050-f62f-4b22-a11b-78f8bcbea0b6 | A 33-year-old man is diagnosed with essential hypeension. He is staed on a blood pressure medication, and after 6 weeks, he notes fatigue, rash over his face, joint aches, and effusions. A serum antinuclear antibody (ANA) test is positive. Wof is the most likely agent | Propranolol | Nifedipine | Thiazide diuretic | Hydralazine | 3d | single | VASODILATORS Hydralazine/Dihydralazine Adverse effects:- are frequent and mainly due to vasodilatation. * Facial flushing, conjunctival injection, throbbing headache, dizziness, palpitation, nasal stuffiness, fluid retention, edema, CHF. * Angina and MI may be precipitated in patients with coronary aery disease. * Post... | Pharmacology | Cardiovascular system | [
"propranolol",
"hydralazine",
"nifedipine"
] | 51,622 |
03675637-6c06-49c2-9def-fafcec6b3b51 | Kamla Rani, a 20 yrs old female having mitral stenosis class II and Rheumatic hea disease becomes pregnant. Which is not indicated in her management during labor: | Give Prophylactic antibiotics | Apply Outlet forceps in 2nd stage of labor | Give iv furosemide at delivery of placenta | Give Methergin at delivery of anterior shoulder | 3d | single | Use of ergometrine/methergin, with or following delivery, is contraindicated in patients with cardiac disease. Ref: Dewhurst's Textbook of Obstetrics and Gynaecology, 5th edition, Page 224 ; Textbook of Obstetrics By Dutta, 4th Edition, Page 541 and 6th Edition, Page 280 | Gynaecology & Obstetrics | null | [
"furosemide"
] | 51,650 |
c5a13143-3f1d-4272-a1c4-6b2da99ea737 | Which among the following does not cause hyperpyrexia? | MAO Inhibitors | Alcohol | Atropine | Amphetamine | 1b | single | Ans. (B) Alcohol(Ref: Modi's Medical Jurisprudence and Toxicology, 23th/e p313)Ethyl alcohol causes vasodilatation and peripheral circulation increases, resulting in a feeling of warmth, but at the same time there will be loss of body heat from the skin.In atropine poisoning, Pyrexia (hot as a hare) is a common event a... | Pharmacology | Miscellaneous | [
"atropine"
] | 51,666 |
809ae052-97d7-49b6-a13a-ea72df8ac9b9 | Highly vestibulotoxic drug is : | Cisplatin | Streptomycin | Dihydrostreptomycin | Quinine | 1b | single | null | Pharmacology | null | [
"quinine",
"cisplatin"
] | 51,683 |
e92804ac-8dd9-48c5-9bc6-7a5d16e6eaeb | In LVF, the drug which can be administered is: | Propanlol | Morphine | Amlodipine | Epinephrine | 1b | single | Morphine is given in left ventricular failure as it decreases peripheral pooling of blood, decreases preload, shifts blood from pulmonary to systemic circuit, relives pulmonary edema and congestion It depresses resp. center and decreases air hunger Ref: KD Tripathi 8th ed | Pharmacology | Cardiovascular system | [
"morphine",
"epinephrine",
"amlodipine"
] | 51,735 |
dbf70338-5bd9-49ca-aa01-21760322d3c1 | An old patient Ram Kishore having asthma and glaucoma is to receive a β blocker. Regarding β blocking drugs: | Metoprolol blocks β2 receptors selectively | Esmolol's pharmacokinetics are compatible with chronic topical use | Nadolol lacks β2 blocking action | Timolol lacks the local anaesthetic effects of propranolol | 3d | single | null | Pharmacology | null | [
"propranolol",
"nadolol",
"metoprolol",
"esmolol",
"timolol"
] | 51,738 |
1dbbf8f7-604f-4b45-bad8-a5cf8f4a5a50 | Which of the following can cause hypoglycemia in a patient of severe cerebral malaria on treatment ? | Quinine | Chloroquine | Halofantrine | Mefloquine | 0a | single | null | Pharmacology | null | [
"quinine",
"mefloquine",
"chloroquine"
] | 51,742 |
90997355-a3f5-4a62-8f41-e50c30daa7e8 | All of the following pharmaceutical agents cause gynaecomastia, EXCEPT: | INH | Cimetidine | Digitalis | Pyrazinamide | 3d | multi | Pyrazinamide will cause gynaecomastia. List of drugs which cause gynaecomastia are: Hormones Androgens and anabolic steroids Chorionic gonadotropin Estrogens and estrogen agonists Growth hormone Environmental estrogens Antiandrogens or inhibitors of androgen synthesis Cyproterone Flutamide Bicalutamide Antibiotics Ison... | Pharmacology | null | [
"cimetidine"
] | 51,762 |
9c4013bb-d194-4f88-bb2d-31c3f448aeea | Ejection of milk is caused by | Oxytocin | ADH | Progesterone | Thyroxine | 0a | single | Oxytocin plays roles in sexual reproduction, in paicular during and after childbih. It is released in large amounts after distension of the cervix and uterus during labor, facilitating bih, maternal bonding, and, after stimulation of the nipples, breastfeeding. Both childbih and milk ejection result from positive feedb... | Physiology | Endocrinology | [
"oxytocin",
"thyroxine"
] | 51,783 |
224758e1-c712-4e5d-8ec7-4ad8e00af404 | Drug used for treatment of influenza is - | Ritonavir | Idoxuridine | Lumefantrine | Oseltamivir | 3d | single | Ans. is 'd' i.e., Oseltamivir o Anti-influenza drugs are:-i) Amantidineii) Rimantidineiii) Oseltamiviriv) Zanamavir | Pharmacology | Anti-Viral | [
"ritonavir",
"oseltamivir"
] | 51,796 |
e3c94852-de8f-4d6d-b4d8-e850179b05a8 | All are true regarding antiarrhythmic, EXCEPT : | Verapamil belongs to second group drugs | Contraindicated in Sick sinus syndrome | It is contraindicated in complete heart block. | It depresses heart rate | 0a | multi | Ans. is 'a' i.e. Verapamil belongs to second group drugs Verapamil is a calcium channel blocker. It belongs to class IV anti-arrhythmic drugs. Electrophysiological properties of verapamil. Among the Ca2+ channel blockers, verapamil has the most prominent cardiac electrophysiological action. It is a cardio depressant dr... | Unknown | null | [
"verapamil"
] | 51,799 |
e9be813e-4c2c-44bf-9b66-884c20cc71e2 | All the following drugs act on the Microtubular Protein Tubulin EXCEPT: | Colchicine | Vincristin | Bleomycin | Paclitaxel | 2c | multi | Bleomycin | Pharmacology | null | [
"paclitaxel",
"colchicine"
] | 51,800 |
1c245d0e-1ab7-4828-a65c-2d473ec787a2 | Smooth induction is seen by - | Ether | Halothane | Isoflurane | Enflurane | 2c | single | Ans. is 'c' i.e., Isoflurane Induction by inhalation agents Unpleasant Intermediate Smooth Ether Halothane Isoflurane En flurane Desflurane Sevoflurane Nitrous oxide | Anaesthesia | null | [
"enflurane",
"isoflurane",
"halothane"
] | 51,812 |
80d7cc70-4f4a-4ea3-beed-835681009b02 | Warfarin embryopathy is due to action of: | Osteophysin | Osteotensin | Osteocalcin | Osteogenin | 2c | single | Ans: (c) OsteocalcinRef: style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 0 4px">Warfarin embryopathyThe process of osteocalcin carboxylation in human bone formation is a vitamin K-dependent process and that circulating osteocalcin will be altered structurally by warfarin ad... | Pharmacology | Hematology | [
"warfarin"
] | 51,835 |
1518c60a-317d-4fe5-8387-842386ad4173 | Which of the following is called hunger hormone | Epinephrine | Glucagon | Pituitary | Thyroxine | 1b | multi | null | Physiology | null | [
"epinephrine",
"thyroxine",
"glucagon"
] | 51,838 |
5aee8115-72a7-41c7-8433-b58dbdff38a6 | A 59 year old man with severe myxomatous mitral regurgitation is asymptomatic. His echo shows a left ventricular ejection fraction of 45% and an end-systolic diameter index of 2.9 cm/m2. Which of the following represents the most appropriate mode of treatment ? | No treatment | ACE inhibitor therapy | Mitral valve repair or replacement | Digoxin and diuretic therapy | 2c | single | This man is asymptomatic, but his left ventricular ejection fraction is 45%, so the most appropriate treatment is mitral valve repair or replacement. Indications of surgical repair of mitral valve are patients who are symptomatic, asymptomatic patients with left ventricular ejection fraction less than 60% and/or end-sy... | Medicine | null | [
"digoxin"
] | 51,845 |
73f56eb3-2cc3-4b3a-bf29-6da71a5ca3d0 | The renal biopsy of a 6-year-old boy with recurrent gross hematuria shows IgA nephropathy. The urinary protein excretion is 130 mg/day. Which of the following is the most appropriate next step in the management - | Administer coicosteroids | Give Azathioprine | Sta Cyclosporine | Urinary bag sample | 0a | multi | Ans. is 'a' i.e., Administer coicosteroids T/T of IgA nephropathy ? o There is no proven t/t for IgA nephropathy. o The primary t/t is proper blood pressure control. The drugs which have been proved useful are :? i) Fish oil (It contains omega - 3 fatty acids). It is an antiinflammatory agent and it prevents the rate o... | Pediatrics | null | [
"azathioprine",
"cyclosporine"
] | 51,852 |
f1faa205-d55e-446b-a348-b58da8f652a4 | Which of the following topical steroids is the most potent? | Halobetasol propionate | Fluticasone | Hydrocortisone | Triamcinolone acetonide | 0a | single | Ans. is 'a' i.e., Halobetasol propionate Classification of topical steroids based on potencyClass 1(Super potent)Clobetasol propionate ointment and cream 0.5%Betamethasone dipropionate ointment 0.05%Halobetasol propionate ointment and cream 0.05%Class 2(Highly potent)Mometasone furoate ointment 0.1%Class 3(Potent)Betam... | Pharmacology | Endocrinology | [
"triamcinolone"
] | 51,861 |
9db0b36f-da7a-4436-8583-268f6e709197 | Which of the following is most uroselective anticholinergic drug? | Darifenacin | Tolbutamide | Duloxetine | Tamsulosin | 0a | single | Muscarinic anatagonists acting on bladder : SOFT BLADDER S - solifenacin O - Oxybutynin F - Flavoxate T - Tolterodine , Trospium chloride Bladder- Darifenacin Side effects - Urinary Retention Tolbutamide is sulfonylureas , used as a hypoglycemic agent,stimulates the secretion of insulin by the pancreas Duloxetine is us... | Pharmacology | ANS | [
"tamsulosin",
"duloxetine",
"tolbutamide"
] | 51,867 |
8d184219-0ad4-4a7e-a005-8ae2064b8658 | Pseudolymphoma is a manifestation of ? | Phenytoin | Carbamazepine | Sodium valproate | Phenobarbital | 0a | single | Ans. is 'a' i.e., Phenytoin Phenytoin on long term administration can lead to lymphadenopathy which is sometimes difficult to distinguish from malignant lymphoma. It is known as pseudolymphoma. | Pharmacology | null | [
"valproate",
"carbamazepine",
"phenytoin",
"phenobarbital"
] | 51,880 |
94c13eea-0868-474f-b0d7-769b129a53f5 | A Schizophrenic patient is responding well to haloperidol. But, now he has developed symptoms of parkinsonism. What is the drug of choice to treat this condition - | Levodopa | Bromocriptine | Tolcapene | Anticholinergic | 3d | single | Ans: D AnticholinergicExtrapyramidal side effects of antipsvchotics.Major dose limiting side effects.Maximum with halopridol.Parkinsonism:Appears between 1-4 weeks of therapy.Central anticholinergics like benzhexol are durg of choice for drug induced Parkinsonism. | Pharmacology | null | [
"bromocriptine",
"levodopa"
] | 51,899 |
f8450403-f378-48bd-8438-8e9024a32ce1 | Which of these is an FDA approved indication for use of modafinil as an adjunct ? | Major depression and associated lethargy | Narcolepsy | Obstructive sleep apnea | Shift work disorder | 2c | single | null | Pharmacology | null | [
"modafinil"
] | 51,900 |
59b28f30-f3a1-41ce-b1c6-b42f518ad1be | Which of the following drugs is most effective in the management of malignant hyperthermia ? | Baclofen | Dantrolene | Succinylcholine | Vecuronium | 1b | single | null | Pharmacology | null | [
"dantrolene",
"vecuronium",
"baclofen"
] | 51,907 |
e201dd2d-4689-4d25-9608-522194e06aae | All the following features are associated with Chancroid except- | Painful ulcer | Painless lymphadenopathy | School of fish appearance on staining | Azithromycin is useful in treatment | 1b | multi | Ans is 'b' i.e. Painless lymphadenopathy* Chancroid is associated with painful suppurative inguinal lymphadenopathy.Chancroid (soft chancre/soft sore)* Chancroid is an STD caused by H.ducreyi, a gram negative cocobacilli. Incubation period of chancroid is 1-7 days. Clinically it is characterized by: -i) Multiple ulcers... | Skin | S.T.D. | [
"azithromycin"
] | 51,911 |
950862f7-a707-4458-be3f-bdcbe30695b7 | Ulipristal acetate is used for | Breast cancer | Endometriosis | Emergency contraception | AUB | 2c | single | This drug is a SPRM (selective progesterone receptor modulator). It is used for emergency contraception and is the only hormonal contraception that is effective for 120 hrs. It is contraindicated in hepatic disorder and in lactational mothers. For emergency contraception. a 30 mg tablet is used within 120 hours (5 days... | Anatomy | All India exam | [
"ulipristal"
] | 51,934 |
cdd9fab3-00ba-4a22-b913-8cd833e94c96 | Which of the following is given to a patient who is planned for ECT: September 2003 | Diazepam | Phenytoin | Muscle relaxant | Barbiturate | 2c | single | Ans. C i.e. Muscle relaxant | Psychiatry | null | [
"phenytoin",
"diazepam"
] | 51,944 |
78dc20f9-3ef1-4b6c-b3d4-81bf65148cf5 | All the following drugs are used for thrombo prophylaxis except | Heparin | Warfarin | Aspirin | Anti thrombin | 3d | multi | Ans is 'd' i.e. Anti thrombin | Pharmacology | Anticoagulants and Coagulants | [
"warfarin"
] | 51,969 |
22ce9958-b969-4dda-9022-b446b3983a53 | In a patient with chronic congestive cardiac failure, all of the following drugs prolong survival, except? | Metoprolol | Carvedilol | Enalapri I | Digoxin | 3d | multi | Ans. is 'd' i.e., Digoxin Arrest of disease progression and reduced moility in CHFo The major humoral abnormalities in hea failure, which are responsible for disease progression, cardiac remodelling and moility, are excessive activation of the RAA system and adrenergic system.o The drugs which block the effect of RAA s... | Pharmacology | null | [
"carvedilol",
"metoprolol",
"digoxin"
] | 51,972 |
49cbe634-1394-469c-a3ce-926db17f0f74 | Which of the following anti TB drug is NOT bactericidal | Rifampicin | Isoniazid | Pyrazinamide | Ethambutol | 3d | single | Ans. (d) EthambutolRef. KDT/742* Ethalmbutol is selectively tuberculostatic and clinically as active as Streptomycin.1st Line ATT Drugs action on bacteria and hepatoxictyDrugBactericidal/ BacteristaticHepatotoxicityIsoniazidCidal+RifampicinCidal+PyrazinamideCidal++++EthambutolSTATIC-NoStreptomycinCidal-No | Pharmacology | Anti Microbial | [
"ethambutol",
"isoniazid"
] | 51,981 |
87f6356e-82bd-491c-94a2-14ab0deab9aa | A highway truck driver has profuse rhinorrhea and sneezing. Which of the following drugs would you prescribe him? | Cetrizine | Pheniramine | Promethazine | Dimenhydrinate | 0a | single | As the patient in the question is a truck driver, antihistamine which is best suitable for him is cetrizine. Cetirizine is a second generation antihistamine with least sedation. Promethazine and Dimenhydrinate are highly sedative and Pheniramine is moderately sedative preparations of H1 antihistamine which is not prefe... | Pharmacology | null | [
"promethazine"
] | 51,985 |
d993bb8f-846b-48e0-8af4-a2899b432648 | All of the following statements about Digoxin induced arrhythmia's are true, except: | Bi ventricular Tachycardia | Paroxysmal Atrial Tachycardia with variable AV block | Ventricular Bigeminy | May be used to treat Atrial Fibrillation | 0a | multi | The most frequent disturbances of cardiac rhythm associated with digitalis intoxication are ventricular premature beats, bigeminy, ventricular tachycardia and rarely ventricular fibrillation. AV block and nonparoxysmal atrial tachycardia with variable AV block are characteristic of intoxication. Ref: Harrison's 16th Ed... | Medicine | null | [
"digoxin"
] | 51,986 |
9d2c0fd0-096d-4494-9118-05851254db1a | The following antibiotic accentuates the neuromuscular blockade produced by pancuronium | Streptomycin | Penicillin | Chloramphenicol | Erythromycin | 0a | single | DRUG INTERACTIONS Antibiotics:- Aminoglycoside antibiotics (streptomycin) reduce Ach release from prejunctional nerve endings by competing with Ca2+. They interfere with mobilization of ACh containing vesicles from a central location to near the terminal membrane, and have a weak stabilizing action on the postjunctiona... | Pharmacology | Anesthesia | [
"erythromycin",
"chloramphenicol",
"pancuronium"
] | 51,993 |
231731aa-d3f8-4115-bff1-3aa5e7527eee | The drug used in coronary aery stenosis during Angio procedure? | Pindolol | Octreotide | Desmopressin | Tolazoline | 3d | single | Talazoline is used as a vasodilator for angio proccedures. Non-selective alpha blockers like phentolamine and tolazoline are used for this purpose. Ref: CMDT-2010/Pg 1434. | Pharmacology | Cardiovascular system | [
"desmopressin",
"pindolol",
"octreotide"
] | 52,000 |
975cd87c-32b5-4d37-bec1-0c56fe973c2d | Which of the following is a long-acting beta 2 against - | Orciprenaline | Penoterol | Pexbaterol | Salmeterol | 3d | single | β2,-agonists used in Asthma 1. Short acng → Salbutamol, terbutaline
2. Long acng → Salmeterol, formoterol Bambuterol is a prodrug of terbutaline. It is slowly hydrolysed by pseudocholineterase.
Short-acting β2-agonists produce bronchodilation within 5 min and action lasts for 2-6 hrs →
are used to abort and terminat... | Pharmacology | null | [
"salmeterol"
] | 52,007 |
ec6af887-0794-4731-b0c1-313f3836086d | Initial drug of choice in a child with status epilepticus – | Lorazepam | Phenobarbitone | Valproate | Phenytoin | 0a | single | Drug used are → Lorazepam, Clonazepam, Diazepam, Phenytoin, Phenobarbitone, Thiopentol, Propofol, Midazolam.
Lorazepann i.v. is now the preferred initial choice. | Pediatrics | null | [
"valproate",
"lorazepam",
"phenytoin"
] | 52,010 |
55c4ebde-f087-4826-882f-bfbf02d48e76 | A previously healthy and active 72-year-old woman presents to your office with a complaint of stiffness and pain in her neck and shoulders. The symptoms are much worse in the morning and improve throughout the day. The pain affects the soft tissues and does not appear localized to the shoulder or hip joints. She denies... | Empiric trial of prednisone 15 mg daily | Graded exercise regimen | MRI of bilateral shoulders | Trapezius muscle biopsy | 0a | multi | The patient has PMR. A relatively common disease of the elderly, PMR presents as morning stiffness and pain in the shoulders, neck, and hip girdle. Diagnosis is mainly clinical; improvement of symptoms throughout the day and an absence of joint findings on physical examination provide clues to the diagnosis. Most patie... | Medicine | Immunology and Rheumatology | [
"prednisone"
] | 52,014 |
d097868d-da81-45ed-b306-8448fb104636 | A 70 year old man presents with complaints of chest pain, fever, cough with sputum. On examination of sputum pus cells with gram positive cocci are present. Blood agar showed positive result. How will you differentiate this from other gram positive cocci? | Bacitracin sensitivity | Optochin sensitivity | Bile solubility | Positive coagulase | 2c | single | Pneumococci are bile soluble. If a few drops of 10% sodium deoxycholate solution are added to 1 ml of an overnight broth culture, the culture clears due to the lysis of cocci. Alternatively, if a loopful of 10% deoxycholate solution is placed on a pneumococcus colony on blood agar the colony lysis within a few minutes.... | Microbiology | null | [
"bacitracin"
] | 52,020 |
e2f3c992-3816-47a8-8039-0a30eb35d602 | which of the following drugs should be removed by dialysis? | digoxin | salicylates | benzodiazepines | organophosphates | 1b | single | Salicylates stay in blood whereas digoxin,diazepam and organophosphates are distributed widely | Anatomy | General anatomy | [
"digoxin"
] | 52,055 |
095e14fc-b95d-4d6d-9837-6c8fb56c573d | OCP fails when used with the following drugs, EXCEPT: | Aspirin | Phenytoin | Rifampin | Tetracycline | 0a | multi | Larger doses of aspirin may be required when given with oral contraceptive pills. Drugs that May Reduce Combined Hormonal Contraceptive Efficacy: Antituberculous Rifampin Antifungals Griseofulvin Anticonvulsants and Sedatives Phenytoin Mephenytoin Phenobarbital Primidone Carbamazepine Ethosuximide Antibiotics Tetracycl... | Pharmacology | null | [
"rifampin",
"tetracycline",
"phenytoin"
] | 52,080 |
51b7e05c-bfd4-4107-9f30-40a4b21925bd | A 60-year-old male complains of pain in both knees coming on gradually over the past 2 years. The pain is relieved by rest and worsened by the movement. There is bony enlargement of the knees with mild inflammation. Crepitation is noted on motion of the knee joint. There are no other findings except for bony enlargemen... | Weight reduction | NSAID's and Calcium supplementation | Total knee replacement | Oral prednisone | 0a | multi | (Braunwald, 15/e, pp 1987-1993.) The clinical picture of a noninflammatory ahritis of weight-bearing joints is suggestive of degenerative joint disease, also called osteoahritis. Crepitation over the involved joints is characteristic, as are bony enlargements of the DIP joints. In this overweight patient, weight reduct... | Surgery | null | [
"prednisone"
] | 52,094 |
2b0eec7d-f0fb-4802-9809-34891dee6781 | Which of the following statements are true regarding benzodiazepines? | It acts as GABA agonist | Diazepam is a sho acting benzodiazepines | Diazepam causes lesser respiratory depression than midazolam | Nitrazepam is metabolized in liver | 2c | multi | Benzodiazepines act on BZD receptors of GABAA-BZD receptor-chloride channel complex and increase the frequency of CI -channel opening GABA facilitatory action. Thus these are not GABA agonists. Coma, respiratory depression though rare,can occur with ultra sho acting agents like midazolam,thriazolam. Diazolam has rapid ... | Pharmacology | Central Nervous system | [
"midazolam",
"diazepam"
] | 52,105 |
71abb2f3-32bd-4ccd-bb0d-ec2ece093727 | Drug of choice for treatment of infestation due to Onchocerca volvolus is : | Albendazole | Ivermectin | Praziquantel | Suramin | 1b | single | null | Pharmacology | null | [
"albendazole",
"ivermectin"
] | 52,106 |
8e02b885-9dcd-4fff-97e5-7991bd9f5f9a | Drugs used for anaesthesia in a hypotensive is? | Propofol | Ketamine | Thiopentone | None | 3d | multi | Ans. is 'b' i.e., Ketamine Ketamine raises the BP, therefore is the induction agent of choice in hypotensive states and shock | Anaesthesia | null | [
"ketamine",
"propofol"
] | 52,107 |
cb5667f9-70a3-4b7b-b5c3-e0b17efb9dff | Best forensic sample for DNA analysis is: TN 09 | Blood in EDTA | Hair | Vitreous humor | Femur bone | 0a | single | Ans. Blood in EDTA | Forensic Medicine | null | [
"edta"
] | 52,109 |
dc9bf7df-55e5-4f26-bdc2-a60c0eb95292 | A young man presents with asymptomatic macules and erythematous painless lesion over glans with generalized lymphadenopathy. Treatment of choice in this condition: | Ceftriaxone | Benzathine penicillin | Acyclovir | Fluconazole | 1b | single | Ans. b. Benzathine penicillin (Ref: Fitzpatrick's 6/e p2164-2212; Rooks Textbook of Dermatology 7/e p30.1-35, 25.20-39)Asymptomatic macules and papule over the trunk and reddish patch over the palate with a flat, moist lesion on glans penis in a young man with generalized lymphadenopathy is suggestive of syphilis.Benza... | Unknown | null | [
"fluconazole",
"ceftriaxone"
] | 52,114 |
c4a81534-7243-40bd-a8a1-895f81db3330 | Drugs acting on dopamine receptors are all except | Dopamine | Fenoldopam | Dobutamine | Haloperidol | 2c | multi | -Dopamine It stimulates 3 receptors Receptors Dose of Dopamine for stimulation D1 <2 mg/Kg/min b1 2-10 mg/Kg/min a1 >10 mg/Kg/min -Fenoldopam is dopamine agonist -D1 Used in hypeensive emergency -Dobutamine Does not act on dopamine receptors Mainly act on beta 1 Used in CHF -Haloperidol - typical antipsychotic with D2 ... | Pharmacology | Sympathetic System | [
"fenoldopam",
"dobutamine"
] | 52,119 |
78e9e758-8ea1-402c-b8d7-619155a5dfe8 | Scabies oral drug of choice: | Permethrin | Benzyl Benzoate | Ivermectin | Lindane | 2c | single | Ref: Katzung, 14th ed. pg. 939, 1075; KDT, 6th ed. pg. 864* Scabies is caused by an ectoparasite sarcoptes scabei. It is highly contagious. The mite burrows through the epidermis, laying eggs which form papules that itch intensely.* Most common site of entry- finger webs.* Drugs used are:# Permethrin 5%: broad spectrum... | Pharmacology | Anti Microbial | [
"ivermectin"
] | 52,154 |
3c9b142e-ea01-4676-a8bf-06923b8732ef | Which of the following is a GLP-1 agonist? | Pramlintide | Exenatide | Sitagliptin | None of the above | 1b | multi | Alpha-Glucosidase inhibitors |Glucose absorption Acarbose, Miglitol Dipeptidyl peptidase IV inhibitors Prolong endogenous GLP-1 action Sitagliptin GLP-1 agonist |Insulin, |Glucagon, slow gastric emptying Exenatide Amylin agonist Slow gastric emptying, |Glucagon Pramlintide Ref: KD TRIPATHI 8TH ED. | Pharmacology | Endocrinology | [
"sitagliptin",
"exenatide",
"pramlintide"
] | 52,157 |
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