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In molecular biology, SNORA21 (also known as ACA21) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.This family also contains the mouse sequence MBI-3. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA21 |
In molecular biology, SNORA22 (also known as ACA22) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA22 |
In molecular biology, SNORA24 (also known as ACA24) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA24 |
In molecular biology, SNORA25 (also known as ACA25) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA25 |
In molecular biology, SNORA26 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.The snoRNA HBI-6 belong to the H/ACA family of snoRNAs, guiding the pseudouridylation of position U4522 of the 28S rRNA. HBI-6 is the human orthologue of mouse MBI-6 snoRNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA26 |
In molecular biology, SNORA27 (also known as ACA27) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA27 |
In molecular biology, SNORA28 (also known as ACA28) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA28 |
In molecular biology, SNORA29 (also known as ACA29) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.The family also contains the mouse sequence MBI-39. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA29 |
In molecular biology, SNORA30 (also known as ACA30) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of eukaryotic cells. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA' as it 'guides' the modification process. ACA30 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs based on its structure and the proteins it is associated with. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA30 |
snoRNA ACA30 is predicted to guide the pseudouridylation of U4643 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine(Ψ). This snoRNA is related to other snoRNAs identified in human (ACA37) and mouse (MBI-26). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA30 |
In molecular biology, SNORA32 (also known as ACA32) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA32 |
In molecular biology, SNORA33 (also known as ACA33) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA33 |
In molecular biology, SNORA38 (also known as ACA38) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA38 |
In molecular biology, SNORA4 (also known as ACA4) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA4 |
In molecular biology, SNORA41 (also known as ACA41) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.The family also includes the mouse sequence MBI-83. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA41 |
In molecular biology, SNORA42 (also known as ACA42) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA42 |
In molecular biology, SNORA5 (also known as ACA5) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA5 |
In molecular biology, SNORA65 (also known as U65) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'. U65 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA65 |
snoRNA U65 is predicted to guide the pseudouridylation of residues U4373 and U4427 of 28S ribosomal RNA (rRNA). Pseudouridylation is the isomerisation of the nucleoside uridine to pseudouridine(Ψ). U65 is related to the snoRNA MBII-351 identified in mouse. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA65 |
In molecular biology, SNORA66 (also known as U66) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA". | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA66 |
U66 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. U66 is predicted to guide the pseudouridylation of U119 of 18S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA66 |
In molecular biology, SNORA7 (also known as ACA7) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.The family also contains the mouse sequence MBI-141. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA7 |
In molecular biology, SNORA76 (also known as ACA62) is a non-coding RNA (ncRNA) which modifies other small nuclear RNAs (snRNAs). It is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis. ACA62 is proposed to guide the pseudouridylation of 18S rRNA U34 and U105. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA76 |
In molecular biology, SNORA8 (also known as ACA8) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA8 |
In molecular biology, SNORA9 (also known as ACA9) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA9 |
In molecular biology, SNORD15 (also known as U15) is a non-coding RNA (ncRNA) molecule which functions in the modification of small nuclear RNAs (snRNAs, also a type of ncRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. U15 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD15 |
Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. U15 is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue A3764.In humans there are two closely related copies of the U15 snoRNA (called SNORD15A and SNORD15B). They are both encoded in the introns of the ribosomal protein S3. In Xenopus laevis it is located within the introns of ribosomal protein S1 snoR75 from Arabidopsis thaliana and homologues in rice Oryza sativa and other plants are alternatively known as U15, and, despite a significantly shorter sequence length, appear to be related. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD15 |
In molecular biology, SNORD17 (also known as HBI-43) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. HBI-43 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD17 |
Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.This snoRNA is the human orthologue of mouse HBI-43. HBII-43 is predicted to guide 2'O-ribose methylation of 28s ribosomal RNA (rRNA) at position U3797. This residue (U3797) is also predicted to be pseudouridylated (the uridine residue is converted to pseudouridine) by the H/ACA box snoRNA ACA48. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD17 |
In molecular biology, SNORD18 (also known as U18) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. U18 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD18 |
Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.In humans and Xenopus laevis there are three closely related copies of U18 (called U18A, U18B, U18C) which are encoded in introns of ribosomal protein L1. In yeast U18 is located in the introns of Elongation Factor 1 beta (EF1-beta). Related snoRNAs in Arabidopsis thaliana and rice Oryza sativa have been named R63 and Z106 respectively. Factors involved in the processing of the intronic snoRNA have recently been elucidated. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD18 |
In molecular biology, SNORD19 (also known as HBII-108) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD19 |
SNORD19 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.HBII-108 is the human orthologue of the mouse MBII-108 and is predicted to guide 2'O-ribose methylation of the small subunit (SSU) ribosomal RNA (rRNA), 18S, on position G683. In the human genome snoRNA HBII-108 is located in the introns of the gene nucleostemin (NS), along with another snoRNA HBII-210. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD19 |
In molecular biology, SNORD29 (also known as U29) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD29 |
U29 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.In humans U29 and several other snoRNAs (U22 and U25-U31) are located in the introns of the same gene (called UHG for U22 host gene). U29 is proposed to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue A4493. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD29 |
In molecular biology, SNORD37 (also known as U37) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD37 |
snoRNA U37 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the C/D box family function in directing site-specific 2'-O-methylation of substrate RNAs.This snoRNA was originally identified by computational screening of vertebrate genomes for conserved C/D box motifs within intronic regions and expression experimentally verified by northern blotting. The mouse orthologue was identified.SNORD37 is predicted to guide the 2'O-ribose methylation of the 28S ribosomal RNA (rRNA) at residue A3697. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD37 |
In molecular biology, SNORD47 (also known as U47) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD47 |
snoRNA U57 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.This snoRNA was originally cloned from HeLa cells and expression verified by northern blotting. It is predicted to guide 2'O-ribose methylation of ribosomal RNA (rRNA) 28S at residue C3866. The mouse orthologue was also clonedThis snoRNA is encoded in the introns of the same genes as other C/D box snoRNAs U44, U74, U75, U76, U77, U78, U79, U80 and U81. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD47 |
In molecular biology, SNORD48 (also known as U48) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD48 |
U48 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.This snoRNA was originally cloned from HeLa cells and experimentally verified by northern blotting. SNORD48 is predicted to guide the 2'O-ribose methylation of 28S rRNA C2279. In the human genome this snoRNA is located in the introns of the same host gene (C6orf48) as another C/D box snoRNA U52 (also known as SNORD52). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD48 |
In molecular biology, SNORD51 (also known as U51) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD51 |
U51 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.This snoRNA was originally cloned from HeLa cells and expression verified by northern blotting. It is predicted to guide 2'O-ribose methylation of ribosomal RNA (rRNA) 28S residue A1511. In the human genome it is located in the introns of the same gene as the H/ACA box snoRNA ACA41. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD51 |
In molecular biology, SNORD64 (also known as HBII-13) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNORD64 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD64 |
Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.snoRNA HBII-13 is expressed mainly in the tissues of brain, but is also in the lungs, the kidneys and muscle; however HBII-13 has no identified target RNA. The HBII-13 gene is located in a 460 kb intron of the large paternally-expressed transcription unit (SNURF-SNRNP-UBE3A AS) along with several other snoRNAs HBII-436, HBII-437, HBII-438A/B and the clusters of HBII-85, HBII-52. This host gene is an antisense transcript to maternally expressed UBE3A gene. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD64 |
In molecular biology, SNORD65 (also known as HBII-135) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNORD19 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.SNORD65 is the human orthologue of the mouse MBII-135 snoRNA and is predicted to guide 2'O-ribose methylation of the small subunit (SSU) ribosomal RNA (rRNA), 18S, on position U627. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD65 |
In molecular biology, SNORD66 (also known as HBII-142) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. HBII-142 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.HBII-142 is the human orthologue of the mouse MBII-142 snoRNA and is predicted to guide 2'O-ribose methylation of 18S ribosomal RNA (rRNA) at residue C1272.An experiment that looked at 22 different non-small-cell lung cancer tissues found that SNORD33, SNORD66 and SNORD76 were over-expressed relative to matched noncancerous lung tissues. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD66 |
In molecular biology, SNORD67 (also known as HBII-166) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. HBII-166 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.snoRNA HBII-166 is the human orthologue of the mouse MBII-166 and is predicted to guide 2'O-ribose methylation of spliceosomal RNA U6 at residue C60. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD67 |
In molecular biology, SNORD72 (also known as HBII-240) belongs to the C/D family of snoRNAs. It is the human orthologue of the mouse MBII-240 and is predicted to guide 2'O-ribose methylation of the large 28S rRNA at residue U4590. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD72 |
In molecular biology, SNORD77 (also known as U77) belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of large 28S rRNA subunit at position A1521. The C/D snoRNAs U44, U47, U74, U75, U76, U78, U79, U80 and U81 share the same host gene as U77 (non-coding). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD77 |
In molecular biology, SNORD78 (also known as U78) belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of the large 28S rRNA subunit at position G4593. The snoRNAs U44, U47, U74, U75, U76, U77, U79, U80 and U81, also of the C/D family, share the same host gene with U78 (protein non-coding). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD78 |
In molecular biology, SNORD87 (also known as U87) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryote cell which is a major site of snRNA bio genesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA U87 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.U87 was identified by purification from yeast (Saccharomyces cerevisiae) and is the orthologue of mouse MBII-276 | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD87 |
In molecular biology, SNP array is a type of DNA microarray which is used to detect polymorphisms within a population. A single nucleotide polymorphism (SNP), a variation at a single site in DNA, is the most frequent type of variation in the genome. Around 335 million SNPs have been identified in the human genome, 15 million of which are present at frequencies of 1% or higher across different populations worldwide. | https://en.wikipedia.org/wiki/SNP_array |
In molecular biology, STRING (Search Tool for the Retrieval of Interacting Genes/Proteins) is a biological database and web resource of known and predicted protein–protein interactions. The STRING database contains information from numerous sources, including experimental data, computational prediction methods and public text collections. It is freely accessible and it is regularly updated. | https://en.wikipedia.org/wiki/STRING |
The resource also serves to highlight functional enrichments in user-provided lists of proteins, using a number of functional classification systems such as GO, Pfam and KEGG. The latest version 11b contains information on about 24,5 million proteins from more than 5000 organisms. STRING has been developed by a consortium of academic institutions including CPR, EMBL, KU, SIB, TUD and UZH. | https://en.wikipedia.org/wiki/STRING |
In molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. This process is called SUMOylation (sometimes written sumoylation). SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.SUMO proteins are similar to ubiquitin and are considered members of the ubiquitin-like protein family. | https://en.wikipedia.org/wiki/Small_ubiquitin-like_modifier |
SUMOylation is directed by an enzymatic cascade analogous to that involved in ubiquitination. In contrast to ubiquitin, SUMO is not used to tag proteins for degradation. Mature SUMO is produced when the last four amino acids of the C-terminus have been cleaved off to allow formation of an isopeptide bond between the C-terminal glycine residue of SUMO and an acceptor lysine on the target protein. SUMO family members often have dissimilar names; the SUMO homologue in yeast, for example, is called SMT3 (suppressor of mif two 3). Several pseudogenes have been reported for SUMO genes in the human genome. | https://en.wikipedia.org/wiki/Small_ubiquitin-like_modifier |
In molecular biology, Small Cajal body specific RNA 11 (also known as scaRNA11 or ACA57) is a small nucleolar RNA found in Cajal bodies. scaRNAs are a specific class of small nuclear RNAs which localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. ACA57 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs and is found associated with GAR1. ACA57 is predicted to guide the pseudouridylation of the U5 spliceosomal RNA at position U43. | https://en.wikipedia.org/wiki/Small_Cajal_body_specific_RNA_11 |
In molecular biology, Small Cajal body specific RNA 13 (also known as scaRNA13 or U93) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U2 and U5 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.U93 is composed of two tandemly arranged box H/ACA box sequence motifs and belongs to the H/ACA box class of guide RNAs. U93 is predicted to guide pseudouridylation of U2 spliceosomal snRNA residue U54 and residue U53 of snRNA U5. | https://en.wikipedia.org/wiki/Small_Cajal_body_specific_RNA_13 |
In molecular biology, Small Cajal body specific RNA 14 (also known as scaRNA14 or U100) is a small nucleolar RNA found in Cajal bodies. scaRNAs are a specific class of small nucleolar RNAs which localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. U100 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure and the conserved H/ACA-box motifs.U100 is the human orthologue of mouse H/ACA snoRNA MBII-201 which is also included in this family. U100 is predicted to guide the pseudouridylation of U2 snRNA at residue U7. | https://en.wikipedia.org/wiki/Small_Cajal_body_specific_RNA_14 |
In molecular biology, Small Cajal body specific RNA 20 (also known as scaRNA20 or ACA66) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.ACA66 (SCARNA20) is a member of the H/ACA box class of snoRNAs that guide the sites of modification of uridines to pseudouridines. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis. ACA66 is predicted to guide the pseudouridylation of residue U28 in U12 snRNA. | https://en.wikipedia.org/wiki/Small_Cajal_body_specific_RNA_20 |
In molecular biology, Small Cajal body specific RNA 21 (also known as scaRNA21 or ACA68) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.ACA68 (SCARNA21) is a member of the H/ACA box class of snoRNAs that guide the sites of modification of uridines to pseudouridines. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis. ACA68 is proposed to guide the pseudouridylation of residue U19 in U12 snRNA. | https://en.wikipedia.org/wiki/Small_Cajal_body_specific_RNA_21 |
In molecular biology, Small Cajal body-specific RNA 1 (also known as SCARNA1 or ACA35) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U2 spliceosomal RNA at residue U89. scaRNA1 is a non-coding RNA, which are functional products of genes not translated into proteins. Such RNA molecules usually contain important secondary structure or ligand-binding motifs and are involved in many important biological processes in the cell.scaRNA1 belongs to the H/ACA box class of snoRNAs, as it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs, and is found associated with GAR1 protein. | https://en.wikipedia.org/wiki/Small_Cajal_body-specific_RNA |
In molecular biology, Small Nucleolar RNA SNORD100 (also known as HBII-429) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD100 |
SNORD100 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the C/D box family function in directing site-specific 2'-O-methylation of substrate RNAs. SNORD100 is predicted to guide the 2'O-ribose methylation of 18S ribosomal RNA (rRNA) at residue G436. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD100 |
In molecular biology, Small Nucleolar RNA SNORD110 (also known as HBII-55) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD110 |
HBII-55 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2′-O-methylation of substrate RNAs. HBII-55 is predicted to guide the 2′O-ribose methylation of 18S ribosomal RNA (rRNA) at residue U1288. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD110 |
In molecular biology, Small Nucleolar RNA SNORD111 (also known as HBII-82) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNORD111 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2′-O-methylation of substrate RNAs.SNORD111 is predicted to guide the 2′O-ribose methylation of 28S ribosomal RNA (rRNA) at residue G3923.The exact role of these molecules, however, is not currently known. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD111 |
In molecular biology, Small Nucleolar RNA SNORD23 (also known as HBII-115) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNORD23 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD23 |
Most of the members of the C/D box family function in directing site-specific 2′-O-methylation of substrate RNAs. This snoRNA is the human orthologue of mouse snoRNA MBII-115. There is currently no predicted target RNA for SNORD23. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD23 |
In molecular biology, Small Nucleolar RNA SNORD75 (also known as U75) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. U75 (SNORD75) belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD75 |
Most of the members of the box C/D family function in directing site-specific 2′-O-methylation of substrate RNAs. The mouse snoRNA Z19 is orthologous to human U75. U75 is predicted to guide the 2′-O-ribose methylation of 28S ribosomal RNA (rRNA) residue C4032. In humans U75 shares the same non-protein coding host gene (gas5) with 9 other snoRNAs (U44, U47, U74, U76, U77, U78, U79, U80 and U81). | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD75 |
In molecular biology, Small Nucleolar RNA SNORD88 (also known as HBII-180) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNORD88 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD88 |
Most of the members of the C/D box family function in directing site-specific 2′-O-methylation of substrate RNAs. This snoRNA is the human orthologue of mouse snoRNA MBII-180. SNORD88 is also related to mouse snoRNA MBII-211. SNORD88 is predicted to guide the 2′O-ribose methylation of 28S ribosomal RNA (rRNA) residue C3680.There is evidence that SNORD88 is processed into smaller fragments in a similar fashion to a microRNA and can suppress protein expression. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD88 |
In molecular biology, Small Nucleolar RNA SNORD92 (also known as HBII-316) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNORD92 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD92 |
Most of the members of the C/D box family function in directing site-specific 2′-O-methylation of substrate RNAs. This snoRNA is the human orthologue of mouse snoRNA MBII-316. SNORD92 is predicted to guide the 2′O-ribose methylation of 28S ribosomal RNA (rRNA) residue A3846. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD92 |
In molecular biology, Small Nucleolar RNA SNORD93 (also known as HBII-336) is a non-coding RNA (ncRNA) molecule that functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the Eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and is also often referred to as a guide RNA. SNORD93 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD93 |
Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. This snoRNA is the human orthologue of mouse snoRNA MBII-336. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD93 |
SNORD93 is predicted to guide the 2'O-ribose methylation of 18S ribosomal RNA (rRNA) residue A576. Additionally, SNORD93 can be processed into a smaller, microRNA-like fragment (termed snoRNA-derived RNA(sdRNA)) that contributes to the malignant phenotype of breast cancer. The processed piece (sdRNA-93) has been shown to target Pipox, a sarcosine metabolism-related protein whose expression significantly correlates with distinct molecular subtypes of breast cancer. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD93 |
In molecular biology, Small Nucleolar RNA SNORD94 (also known as U94) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNOR94 is a member of the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. SNORD94 is predicted to guide the 2'O-ribose methylation of C62 of the snRNA U6. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD94 |
In molecular biology, Small Nucleolar RNA SNORD98 (also known as HBII-419) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD98 |
SNORD98 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2′-O-methylation of substrate RNAs. SNORD98 is predicted to guide the 2'0-ribose methylation of 18S ribosomal RNA (rRNA) residue G867. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD98 |
In molecular biology, Small Nucleolar RNA SNORD99 (also known as HBII-420) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNORD99 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD99 |
Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. SNORD99 is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA at residue A2774. In the human genome this snoRNA shares the same host gene with the three H/ACA box snoRNAs ACA16, ACA44 and ACA61. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORD99 |
In molecular biology, Small nucleolar RNA ACA49 is a snoRNA, originally cloned in 2004 from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It has no identified target RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_SNORA49 |
In molecular biology, Small nucleolar RNA F1/F2/snoR5a refers to a group of related non-coding RNA (ncRNA) molecules which function in the biogenesis of other small nuclear RNAs (snRNAs). These small nucleolar RNAs (snoRNAs) are modifying RNAs and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. These three snoRNas identified in rice (Oryza sativa), called F1, F2 and snoR5a, belong to the H/ACA box class of snoRNAs as they have the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs. The majority of H/ACA box class of snoRNAs are involved in guiding the modification of uridine) to pseudouridine in other RNAs | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_F1/F2/snoR5a |
In molecular biology, Small nucleolar RNA MBI-28, also known as SNORA3 and ACA3, is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.snoRNA MBI-28 was originally cloned from mouse brain tissues and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_MBI-28 |
In molecular biology, Small nucleolar RNA MBI-87 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".snoRNA MBI-87 was originally cloned from mouse brain tissues and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_snoMBI-87 |
In molecular biology, Small nucleolar RNA MBII-202 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA MBII-202 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.snoRNA MBII-202 was originally cloned from mouse brain tissues. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_MBII-202 |
In molecular biology, Small nucleolar RNA Me18S-Um1356 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me18S-Um1356 |
snoRNA Me18S-Um1356 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 18S U-1356. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me18S-Um1356 |
In molecular biology, Small nucleolar RNA Me28S-Am2589 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Am2589 |
snoRNA Me28S-Am2589 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 28S A-2589. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Am2589 |
In molecular biology, Small nucleolar RNA Me28S-Am2634 (also known as snoRNA Me28S-Am2634) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis of other small nuclear RNAs (snRNAs). Small nucleolar RNAs (snoRNAs) are modifying RNAs and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. snoRNA Me28S-Am2634 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted to guide the 2'-O-methylation of 28S ribosomal RNA (rRNA) residue A-2634.This snoRNA has currently only been identified in the fly species Drosophila melanogaster. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Am2634 |
In molecular biology, Small nucleolar RNA Me28S-Am982 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Am982 |
snoRNA Me28S-Am982 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 28S A-982. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Am982 |
In molecular biology, Small nucleolar RNA Me28S-Cm2645 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Cm2645 |
snoRNA Me28S-Cm2645 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 28S C-2645. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Cm2645 |
In molecular biology, Small nucleolar RNA Me28S-Cm3227 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Cm3227 |
snoRNA Me28S-Cm3227 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 28S C-3227. | https://en.wikipedia.org/wiki/Small_nucleolar_RNA_Me28S-Cm3227 |
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