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View Poll Results: How many games do you want the Knicks to win?
Voters
22. You may not vote on this poll
I'm happy with 30 wins. This team is a work in progress. Give them time.
Jesus Christ Felton's got some speed in that wombat body. He overtook Eric Gordon and Griffin on a break after he picked off Gordon's pass.
And now on that handoff from STAT, he went from the arc for a lay in in half a second
Ray really does have surprising speed. If Felton keep his ascendance going...which in turn will help STAT become the otherworldly dominant inside scorer we in turn need him to be...and Gallo continues solidifying himself.
We will make the playoffs. And a team will not salivate at playing us. Let alone if we get SOME production from the 5, or Azzy comes back strong. I like our chances
Clips suck but they don't conventionally suck. Every one of their starters right now any team would love to have. Even Jordan. Just so young and inconsistent and not good at winning/closing out games. |
Pac 12 Northwest teams’ 2014 BCS gambling odds
NW BCS odds
The Pac-12 is known for its athletic, exciting brand of football, but the question is, what are the odds that a team from the great Northwest can claim the BCS title?
Bovada.lv has posted its odds for the BCS National Championship, and three teams from the Northwest have made the list. The Washington State Cougars were not-so-surprisingly left off—sorry, Mike Leach.
Which of the three programs can make a legitimate run is up for debate, but if you’re a fan of college football in the Northwest, recognition is always welcomed.
Washington Huskies: 100/1
UO and UW have both been recognized in the chase for the BCS title. (Photo: Thomas Boyd/The Oregonian)
The Washington Huskies have been given 100/1 odds at winning the BCS National Championship. That puts them on the same level as prestigious programs such as Rutgers and Michigan State.
If the Huskies are going to make a run at any sort of title—Pac-12 or BCS—it’s going to start with quarterback Keith Price. Unfortunately for the team, if it begins with Keith Price, that means it starts with the blocking up front.
Price underachieved last season, but his performance had more to do with his offensive line. When he’s given the time to make plays, his talent is put on full display. However, when he’s rushed into quick decision making, that’s when his inconsistencies come to surface.
Washington has returning offensive linemen in 2013, which will either re-create the same issues or allow them to jell as a unit. If the latter takes place, we’ll see a whole new team—one that has a chance to compete with most teams in the Pac-12.
Oregon State Beavers: 100/1
Like the Huskies, Mike Riley’s Oregon State Beavers have been given 100/1 odds to win a BCS title. This team surprised everyone in 2012, and it will look to do the same again in 2013.
The Beavers weren’t on most people’s radars last year, but a shocking 6-0 start quickly changed that. They were winning games with their defense, which proved to be a theme throughout much of the year.
In 2013, the Beavers have to choose one quarterback. They switched back and forth between Sean Mannionand Cody Vaz, and while both showed they can lead the team, continuity is an important concept for any championship team.
Oregon State lost its bowl game to the Texas Longhorns, but falling 31-27 shouldn’t eliminate it as a solid group to compete in the Pac-12. The team is on a mission to prove that 2012 wasn’t a fluke, and making a run at a title would do just that.
Oregon Ducks: 13/2
The Oregon Ducks have been given the best chance of any NW team to win the BCS championship. Taking it one step further, they’ve been declared a top-2 team in the entire country—second only to the Alabama Crimson Tide.
Led by tailback De’Anthony Thomasand quarterback Marcus Mariota, the Ducks have the speed and athleticism to compete with anybody. They showed in 2012 that they also have the football IQ to make adjustments, which is going to be crucial in championship run.
If Oregon has anything going against it at this point, it’s the departure of Chip Kelly. The head coach ran one of the most innovative offenses in all of college football, and it will be interesting to see how newcomer Mark Helfrich incorporates his style with Kelly’s system.
When it comes down to it, the Ducks should be just fine in their race for a title. Whether or not 13/2 odds are too high has yet to be seen, but if we’ve learned one thing in recent years, it’s that expectations are extremely high in Eugene. |
Marathon security: 'We got your back'
HOPKINTON – The massive Massachusetts State Police mobile incident command center played a pivotal role in the capture of Dzhokhar Tsarnaev last year.
Tsarnaev is being charged with detonating two bombs at the finish line of last year’s Boston Marathon.
The command center – a 53-foot long tractor-trailer – served as the base of operations and held Gov. Deval Patrick, Boston Mayor Tom Menino and state police Col. Timothy Alben during last year’s manhunt to find Tsarnaev. It was one year ago Friday when police found and arrested Tsarnaev in a boat parked in a Watertown backyard.
The state-of-the-art unit will be in Hopkinton this year as part of heightened security measures. On Friday, it was parked at Hopkinton High School.
There will be cameras installed along the route and officers in both uniform and plain clothes.
Over the past year the unit’s equipment has had major technology and communication upgrades, Alben said. The unit has the ability to downlink footage from the department’s helicopters and transmit radio communications to local, state and federal agencies.
"This is really going to be the nerve center at least for Monday’s operation," Alben said as he gave a tour of the mobile unit Friday morning.
Hopkinton Police Chief Edward Lee said there have been many collaborative efforts between law enforcement agencies to ensure everyone’s safety on Monday. But the added security shouldn’t keep anyone away – it’s going to be a safe family-friendly event, he said.
"We want people to come here," the chief said. "We got your back. We are more than prepared for this event."
Lee joined the department as chief earlier this month.
Inside the mobile command center, there is a conference center with 10 chairs and television monitors mounted along the walls. It’s equipped with telephones and Internet.
"This is where we did our work in Watertown," Alben said.
The equipment downlinks footage from helicopters as far as 19 miles away, he said.
On Monday, state police will have four helicopters circling the course.
"It is not only faster, it is less interrupted," Alben said of the downlink capabilities.
The Marathon is challenging because there is no arena to control who comes in and out.
"There is no such thing as zero risk. I’d say we’ve never been so prepared," he said. "I am confident we will have done as much as we can to prepare for this race."
Alben said they have an unprecedented security plan but doesn’t want people thinking they are in a "police state."
"I’ve heard that comment and is not the intent," he said. "Know that we are here for safety and not to infringe on the event."
Page 2 of 2 - Lee said the start line is going to be different than previous years with everyone – including runners – being screened at security checkpoints.
"The whole common used to be open," he said. "This year it will be cut it half. It provides a better overlay to keep our eyes on things."
There will also be extra fencing making it so the runners and spectators will have no contact.
Both Lee and Alben reminded people to be vigilant.
"Our most important security is going to be people who are here on Monday," Alben said.
"We don’t want anybody to stay home," he said. "Come out and root on the runners, enjoy your neighbors and support friends. But pay attention to what is going on around you."
Jonathan Phelps can be reached at 508-626-4338 or jphelps@wickedlocal.com. Follow him on Twitter @JPhelps_MW. |
Opinion issued December 23, 2004
In The
Court of Appeals
For The
First District of Texas
NO. 01-03-00889-CR
DARRELL MAURICE SINGER, Appellant
V.
THE STATE OF TEXAS, Appellee
On Appeal from the 10th Judicial District Court
Galveston County, Texas
Trial Court Cause No. 01CR2368
MEMORANDUM OPINION
Appellant, Darrell Maurice Singer, initially pleaded not guilty to the offense
of felony driving while intoxicated (DWI), but he changed his plea to guilty after the
State presented some evidence to the jury. The trial court instructed the jury that
appellant had changed his plea to guilty, and the trial proceeded before the same jury
for determination of appellant’s punishment. Appellant pleaded not true to a
punishment enhancement paragraph that alleged he had been previously convicted of
the felony of retaliation. The jury found the enhancement paragraph true and
sentenced appellant to 13 years in prison. See Tex. Pen. Code Ann. § 49.09 (Vernon
2003). In two issues, appellant contends that he is entitled to a new trial to determine
his punishment because the trial court erred by (1) overruling appellant’s motion for
mistrial following a witness’s testimony that appellant had an “extensive criminal
history” and (2) admitting certain prior judgments of conviction, which were
allegedly not properly authenticated. We affirm.
Background
At midnight on November 24, 2001, Houston Police Officer B. Roper noticed
appellant’s car drift to the shoulder of the road and then abruptly shift back into the
proper lane. Officer Roper followed appellant and, after seeing appellant’s car drift
a second time, initiated a traffic stop. Appellant told Officer Roper that his name was
Cedric Maurice Moore and that his date of birth was June 25, 1964. Officer Roper
conducted field-sobriety tests on appellant, which indicated that he was intoxicated.
After appellant was arrested, he declined to give a breath specimen for the
intoxilizer test. He was uncooperative with Officer Roper and refused to disclose his
true identity. Officer Roper learned appellant’s identity through a pawn slip found
in appellant’s pocket, which showed his name, Darrell Maurice Singer, and address.
When Officer Roper left appellant alone in the interview room at the police station,
appellant urinated on the floor and passed out.
Denial of Motion for MistrialIn his first issue, appellant contends that the trial court erred by overruling his
motion for mistrial “following a deliberately nonresponsive and highly prejudicial
claim,” by Officer Roper, that appellant had an “extensive criminal history.”
Appellant’s complaint concerns testimony by Officer Roper during the guilt-innocence phase of the trial. The record shows that the trial court sustained
appellant’s attorney’s objection and instructed the jury to disregard the testimony.
Appellant’s guilty plea followed the allegedly prejudicial testimony.
Appellant’s Request for New Guilt/Innocence Trial?
In a footnote to his appellate brief, appellant states that “the change in plea to
‘guilty’ may have been advisable in view of the court’s refusal to grant a mistrial. In
this sense, it is impossible to unravel the court’s refusal to grant a mistrial from the
overall course of this proceeding.”
“Whether entered with or without an agreed recommendation of punishment
by the State, a valid plea of guilty or nolo contendere ‘waives’ or forfeits the right to
appeal a claim of error only when the judgment of guilt was rendered independent of,
and is not supported by, the error.” Young v. State, 8 S.W.3d 656, 666-67 (Tex. Crim.
App. 2000) (holding that judgment of guilt not rendered independently from trial
court’s ruling on motion to suppress evidence of offense, and that judgment could not
be supported without evidence appellant sought to suppress). To avoid waiver of the
right to appeal after pleading guilty or nolo contendere, the defendant must
demonstrate a nexus—temporal or otherwise—between the error and the judgment
of guilt. See Sanchez v. State, 98 S.W.3d 349, 353 (Tex. App.—Houston [1st Dist.]
2003, pet. ref’d) (holding that appellant’s plea of guilty supported by, and not
rendered independently of, trial court’s ruling on motion to reveal identity of
confidential informant because informant’s testimony was relevant to, and needed for,
defense to prosecution); Brink v. State, 78 S.W.3d 478, 484 (Tex. App.—Houston
[14th Dist.] 2001, pet. ref’d) (holding that right to appeal complaint that trial court
erred by substituting trial counsel waived because appellant pleaded guilty two and
a half months after ruling substituting counsel, and appellant showed no direct nexus
between ruling and his guilt or innocence).
Appellant has not demonstrated any nexus between the trial court’s refusal to
grant a mistrial and appellant’s changing his plea from not guilty to guilty. Instead,
appellant merely posits that “the change in plea to ‘guilty’ may have been advisable
in view of the court’s refusal to grant a mistrial.” Because appellant has neither
asserted nor demonstrated that his decision to change his plea was actually related in
any way to the court’s ruling on his motion for mistrial, we conclude that he has not
asserted any cognizable claim of error in the guilt-innocence phase of trial. See Tex.
R. App. P. 38.1(h); Harris v. State, 784 S.W.2d 5, 27 (Tex. Crim. App. 1989);
Maldonado v. State, 902 S.W.2d 708, 711 (Tex. App.—El Paso 1995, no pet.).
Appellant’s Request for New Punishment Trial
Appellant contends that he is entitled to a new punishment trial because “the
slur of defendant’s having a criminal nature was so broad and unconfined that it could
only have interfered with the jury’s ‘orderly evaluation of the evidence’ during [the]
punishment phase.”
We review a trial court’s denial of a motion for mistrial under an abuse of
discretion standard. Ladd v. State, 3 S.W.3d 547, 567 (Tex. Crim. App. 1999).
Abuse of discretion occurs when the trial judge’s decision was so clearly wrong as
to lie outside that zone within which reasonable persons might disagree. Cantu v.
State, 842 S.W.2d 667, 682 (Tex. Crim. App. 1992). A mistrial halts trial
proceedings when error is so prejudicial that expenditure of further time and expense
would be wasteful and futile. Ladd, 3 S.W.3d at 567. Thus, a trial court may declare
a mistrial if an impartial verdict cannot be reached, or if a verdict of conviction could
be reached, but would have to be reversed on appeal due to an obvious procedural
error. Id. Determining whether an error demands a mistrial must be made by
examining the particular facts of the case. Id. Because our system presumes that
juries follow judicial admonishments to disregard, asking an improper question will
rarely require a mistrial. Id.; Bauder v. State, 921 S.W.2d 696, 698 (Tex. Crim. App.
1996). A mistrial is required only when an improper question is clearly prejudicial
to the defendant and is of a character that suggests the impossibility of withdrawing
the impression produced in the minds of the jurors. Ladd, 3 S.W.3d at 567.
Admissible evidence at the punishment stage of trial includes, but is not limited
to, evidence of a defendant’s prior criminal record, his general reputation, his
character, and opinion testimony regarding his character. Tex. Code Crim. Proc. art.
37.07 § 3(a)(1) (Vernon Supp. 2004-2005). During the punishment stage in this case,
the State introduced evidence that appellant had been previously convicted of four
felony offenses: retaliation, aggravated assault, and two thefts. Appellant had also
been convicted of eleven misdemeanor offenses: three for criminal mischief, one for
resisting arrest, four for assaults causing bodily injury, two for DWI, and one for
driving with a suspended license. Officer Roper’s characterization that appellant had
an “extensive criminal history” was accurate based on the evidence in the record and
was admissible at the punishment stage under article 37.07 of the Code of Criminal
Procedure. Therefore, appellant is not entitled to a new punishment trial on the
ground that the trial court refused to declare a mistrial during the guilt-innocence
stage based on the officer’s statement that appellant had an extensive criminal history.
We overrule appellant’s first issue.
Authentication of Exhibits
In his second issue, appellant contends the trial court erred by admitting seven
judgments of appellant’s previous convictions that were allegedly not “certified
copies of the judgments, and no custodian was proffered to authenticate them.”
Specifically, appellant contends that State’s exhibits 9 through 15 should not have
been admitted because they were not “certified.”
During the punishment phase of appellant’s trial, Bill O’Briant of the
Galveston County Sheriff’s Office compared appellant’s fingerprints to fingerprints
on the judgments of appellant’s prior convictions and concluded that the convictions
were appellant’s. The State then offered exhibits 9 through 19 as conviction records
of appellant. Appellant objected and the following occured:
Appellant: My objection is on the predicate that he is not the custodian
of these records. There is no exception under the business
records law. There has [sic] been no affidavits filed. All
he’s doing is taking a piece of paper that he’s taken from
somewhere and comparing a print from a print card he has.
We’ve had nobody come in here and say who is holding
this piece of paper and what’s the purpose of this piece of
paper. That’s my objection.
State’s attorney:The State offers State’s 9 through 19 as self-authenticating
documents, certified copies.
. . .
The court: The objection is overruled. State’s Nos. 9 through 19 are
admitted.
At the end of the punishment phase, appellant admitted that he committed the
crimes recited in the judgments entered into evidence.
Under rule 902 of the Rules of Evidence, a document is admissible into
evidence as a self-authenticating document if the document is a certified copy of a
public record. Tex. R. Evid. 902(4). Appellant’s objection, however, pertained to
rule 803 of the Texas Rules of Evidence, and not rule 902. Appellant’s objection to
the trial court referred to the “business records law” and complained that the officer
was not the “custodian of these records” and that no business records “affidavits”
were on file. See Tex. R. Evid. 803(6) (authorizing admissibility of documents into
evidence under certain circumstances “if it was the regular practice of that business
activity to make the . . . record . . . as shown by the testimony of the custodian or
other qualified witness, or by affidavit that complies with Rule 902(10) . . . .”). In accordance with settled principles of error preservation, a point of error on
appeal must present the same legal theory that was presented to the trial court through
a timely, specific objection. Sterling v. State, 800 S.W.2d 513, 521 (Tex. Crim. App.
1990); see Tex. R. Evid. 103(a)(1); Tex. R. App. P. 33.1(a). Requiring a specific
objection serves two purposes by (1) informing the trial judge of the basis of the
objection and affords him the opportunity to rule on it, and (2) affording opposing
counsel an opportunity to remove the objection or supply other testimony. Zillender
v. State, 557 S.W.2d 515, 517 (Tex. Crim. App. 1977). The Court of Criminal
Appeals has explained this requirement for specificity: “Whichever party complains
on appeal about the trial judge’s action must, at the earliest opportunity, have done
everything necessary to bring to the judges [sic] attention the evidence rule in
question and its precise and proper application to the evidence in question.” Willover
v. State, 70 S.W.3d 841, 845 n.4 (Tex. Crim. App. 2002).
Because appellant’s point of error on appeal does not comport with his trial
court objection, appellant has waived the right to complain about the alleged lack of
certification of the documents in this appeal. See Sterling, 800 S.W.2d at 521. Conclusion
We affirm the judgment of the trial court.
Elsa Alcala
Justice
Panel consists of Chief Justice Radack and Justices Keyes and Alcala.
Do not publish. Tex. R. App. P. 47.2(b).
|
Feeling betrayed by Greek Prime Minister Alexis Tsipras, who was elected on an anti-austerity ticket, Greek unions launched a 24-hour strike, shutting down public services and preventing dozens of boats, trains and planes from moving.
In protest of tax hikes and an upcoming pensions overhaul, more than 20,000 workers descended on Athens, some carrying balloons that read "the words of Alexis," an insinuation that Tsipras' promises to scrap austerity were little more than hot air.
In a departure from convention, Tsipras' far-left Syriza party urged "mass participation" in Thursday's walkouts, saying the protests would strengthen the Greek government's negotiating stance with its creditors, who have criticized Athens for failing to deliver on some measures.
Party lawmakers responsible for labor policy called on ordinary Greeks to protest "the neoliberal policies and the blackmail from financial and political centers within and outside Greece."
A balancing act
At the very least, they highlighted the difficulty of balancing citizens' concerns over further cuts to social services with demands from Brussels that Greece rein in spending or risk crashing out of the eurozone.
Following months of brinkmanship and increasingly acrimonious, late-night negotiations between Athens and its international creditors, Alexis Tsipras finally relented last July, agreeing to a three-year, 86 billion euro ($92.6 billion) bailout. The money, badly needed to keep Greece afloat financially, came with stringent conditions.
"I am protesting against the government because they are making fools of us," one protestor, a 63-year-old pensioner, was quoted as saying by AFP. "We were better off with the conservatives," a garbage collector said.
Tsipras has said he had little choice but to accept the bailout and the austerity measures that came along with it. His re-election in September seemed to indicate that a majority of Greeks, while angered by the belt-tightening measures, understood his plight.
Yet Greeks in several major cities still took part in the day-long strike, with an estimated 8,000 people turning up in the port city of Thessaloniki, the country's second largest population center.
Thousands more didn't show up for work on several Greek islands, stranding thousands of migrants and refugees looking to continue their journeys to Europe's hinterlands.
A slow recovery
More than a million Greeks still lack gainful employment, according to official statistics. Labor activists say that number is likely even higher.
Greece's national statistics office on Thursday released fresh unemployment data that showed the jobless rate had fallen to 24.6 percent of the registered workforce in August from 24.9 percent a month earlier.
Though the unemployment had fallen to a level not seen since June 2012, it was still the highest among the 19 countries that use the euro currency. Spain, for instance, No. 2 in terms of jobseekers, had a rate of 21.6 percent.
cjc/uhe (AFP, AP, Reuters) |
Tamagusuku
was a chief of the Ryūkyū Islands.
Tamgusuku was a chief of the Okinawan polity of Chūzan from roughly 1314-1336.
He was the third son of Eiji (r. 1309-1313), he was the fourth ruler of the lineage of Eiso (r. 1260-1299).
Succeeding his father Eiji as paramount chief of Okinawa's territorial lords at the age of nineteen, Tamagusuku lacked the charisma and leadership skills to command respect and loyalty from those lords (the anji). A number of these lords rebelled, and the island of Okinawa came to be divided into three kingdoms. Tamagusuku, remaining in Urasoe, became the chief of Chūzan. His failure to institute reforms or innovations in governance is generally claimed as one of the causes of the fall of the lineage (dynasty), which ended with Tamagusuku's son and successor Seii.
The Lord of Ōzato fled south from Tamagusuku's capital at Urasoe and, along with his followers, formed the polity of Nanzan (南山, Southern Mountain).
The Lord of Nakijin, based some distance to the north, declared himself chief of Hokuzan (北山, Northern Mountain). He was succeeded by his only son Seii.
See also
Ryūkyū Kingdom
List of monarchs of Ryukyu Islands
Notes
References
Kerr, George H. (1965). Okinawa, the History of an Island People. Rutland, Vermont: C.E. Tuttle Co. OCLC 39242121
Nussbaum, Louis-Frédéric. (2002). Japan Encyclopedia. Cambridge: Harvard University Press. ; OCLC 48943301
Category:1296 births
Category:1336 deaths
Category:Kings of Chūzan
Category:14th-century Ryukyuan monarchs
Category:13th-century Ryukyuan people
Category:14th-century Ryukyuan people |
The subject application pertains generally to generating displays on a plurality of networked devices. The application is particularly applicable to generating user-selected paid advertising on displays of document processing devices which is generated during idle time of each respective device.
Document processing devices include printers, copiers, scanners, or facsimile machines. Modern day document processing devices frequently include two or more of these functions, and are referred to as multifunction peripherals (MFPs) or multifunction devices (MFDs).
Today, various document processing devices are frequently scattered over an enterprise, or are installed in conveniently accessible locations, such as hotels or airports. Modern document processing devices are extremely powerful, and simplified or intuitive control of such complex devices is frequently provided through a graphical user interface. Such graphical user interfaces may be pointer driven, such as via a mouse, touchpad or trackball, or may employ touch screens. The decreasing cost of such displays, coupled with a desire to make machine/user interaction as easy as possible, has lead to incorporation of larger and larger displays, including color displays, on such devices.
While document processing devices are frequently placed in widely accessible locations, servicing one company or the general public ability, devices typically have large periods of inactivity. |
Ask HN: recommendation for VPS/Dedicated Server - juanefren
I am running a SaaS startup company in Mexico, right now I am using a shared server but now looks like it is time to transfer to something bigger, I would like to hear your recommendations. This is what I need:
Fast service (fast response with requests).<p>Possibility to add sub domain names automatically from shell.<p>Possibility to create databases from shell. (each client uses his own subdomain and his own database)<p>Modern Linux environment. (Preferably Ubuntu 10.04)<p>Not hidden charges<p>I am looking for something around $100 U.S. Dollars/month. I am using Webfaction right now. Their service is very good, but with shared hosting I can't do points 2 and 3 (I have to manually create them each new client is registered). And spending $350/month for a dedicated is just not possible for us
======
mtigas
For a VPS/dedicated where you're manually operating the server and database,
#3 is generally given.
I run a couple of small boxes on Slicehost <http://slicehost.com/> and their
management interface allows you to bring up new boxes / close down boxes as
you need, manage your DNS records, and etc.
If you require shell support, they do have an API to their management
interface [http://www.slicehost.com/articles/2008/3/26/announcing-
the-s...](http://www.slicehost.com/articles/2008/3/26/announcing-the-
slicehost-api) — I've played with it just once, in Python, and found it to be
extremely accessible.
The couple times I've needed support, I got resolved within less than an hour.
Generally, I find that I can resolve minor issues within their management
interface (reboot an instance, get shell access via browser if you have broken
SSHD, etc.).
~~~
mtigas
Additionally, for $5 per box, you can store 3 backup images of the whole
machine — and have two of them operate on a schedule (i.e., one image updates
daily at a certain time, another one updates weekly at a certain time, and you
can store another one manually before a large migration or upgrade if you
want).
This has saved my ass before.
------
kmg
the choice of a VPS or dedicated server depends on what you want - guaranteed
disk i/o (dedicated server) or protection against hardware failures (VPS).
Another thing you want to consider is network latency. If your clients are
also from Mexico, a VPS in Texas/California would be better i guess, than say
a VPS in New York or Europe. I have seen the latency correlate with light
speed + base last mile latency, but ymmv.
But since are managing fine in a shared hosting environment so a VPS might be
the logical next step.
As lzw had already mentioned,
[http://www.hetzner.de/de/hosting/produktmatrix/rootserver-
pr...](http://www.hetzner.de/de/hosting/produktmatrix/rootserver-
produktmatrix-eq/) is by far the cheapest dedicated server I know of, with
awesome hardware specs. We own a couple of servers there and are completely
satisfied with their offering and support. But they are in Germany and a new
server takes about 3-5 days to come up.
If you look for dedicated servers in the US, <http://www.serverbeach.com/> has
a ~100$ server. <http://softlayer.com/> comes close with a $139 entry-level
server.
The usual players in the VPS market are <http://www.linode.com/>,
<http://www.slicehost.com/>, www.rackspacecloud.com/ with a HN member
(<http://news.ycombinator.com/user?id=lsc>) running <http://prgmr.com/xen/>
Creating subdomains and databases - this depends on your linux-fu with djbdns
and postgresql/mysql !
------
drewr
Can't say enough good things about <http://linode.com>. Already inexpensive,
you can pre-pay to make it even cheaper. Super-stable, fast, lots of
datacenter options (TX most likely for you). Support is incomparable (#linode
on oftc is hot), but I've only had one outage in two years so I don't use it
much (it was just a host machine reboot). Tool support and API is the best
I've seen at its price point and better than most much higher.
~~~
juanefren
How do I cancel the service? Should I fill a cancellation form asking me for a
lot of things I don't know? I had a bad experience with ServerPronto trying to
cancel.
------
benologist
I have a couple boxes with <http://hivelocity.com/> that I throw a lot of
traffic at. You can get some pretty sweet bargains on their stuff through this
forum: <http://www.webhostingtalk.com/forumdisplay.php?f=36>
------
eduardo_f
Linode is inexpensive and the control panel is great to do lots of tasks. If
you want a _big_ dedicated server, go for 100tb.
------
sethwartak
from my experience, slicehost.com is great.
------
lzw
For your budget, you can get a dedicated machine with much better specs than
the VPS slices.
<http://www.hetzner.de/en/hosting/produkte_rootserver/eq4/>
8GB RAM, 750GB Hard drive space, 1TB traffic and a truely dedicated machine
there, for 49euros a month. Only downside is you have to pay a 149 euro setup
fee.
I haven't used this service, but I found out about it because someone on this
forum recommended it. It is the best deal I've seen for dedicated hosting by a
good distance.
|
@@ -20,6 +20,7 @@
import java.io.PrintWriter;
import java.io.StringWriter;
+import java.net.UnknownHostException;
/**
* API for sending log output.
@@ -302,6 +303,17 @@
if (tr == null) {
return "";
}
+
+ // This is to reduce the amount of log spew that apps do in the non-error
+ // condition of the network being unavailable.
+ Throwable t = tr;
+ while (t != null) {
+ if (t instanceof UnknownHostException) {
+ return "";
+ }
+ t = t.getCause();
+ }
+
StringWriter sw = new StringWriter();
PrintWriter pw = new PrintWriter(sw);
tr.printStackTrace(pw); |
Wall Street jumps after recovery from Twitter-led drop
NEW YORK U.S. stocks climbed on Tuesday in a broad rally, recovering from sharp declines sparked by a "bogus" Associated Press tweet about explosions at the White House.
A false tweet by hackers of two explosions at the White House that injured U.S. President Barack Obama provoked a steep drop in stocks, before they quickly recovered minutes later.
Thomson Reuters data showed the benchmark S&P 500 index fell 14.6 points, or 0.93 percent, in the space of 3 minutes when the tweet hit the market. With the S&P 500 valued at about $14.6 trillion at the time of the false tweet, the plunge briefly wiped out $136.5 billion of the index's value.
"If that was true that had happened, that's a justified selloff, but because people suffer from information overload, people tend to overreact and don't wait to substantiate things - that is the downside to a 24-7 news cycle," said Jason Weisberg, managing director of Seaport Securities Corp in New York.
"You want instantaneous pricing, you want all the advantages of the technology, well then, you have to live by the negatives that the speed and expediency provide."
The move was a reminder of the May 6, 2010, tumble in markets now known as the "flash crash," when the Dow industrials dropped more than 600 points, eventually piling up a loss of about 1,000 points, in a few minutes before recovering.
Stocks had seen a solid advance before the tweet, lifted by a host of strong corporate earnings, including Travelers Cos Inc (TRV.N), Netflix Inc (NFLX.O) and Coach Inc (COH.N).
After the closing bell, Apple Inc (AAPL.O) climbed 4.9 percent to $425.95 after the iPad and iPhone maker reported second-quarter earnings and unveiled plans to double the amount of capital it returns to shareholders.
The Dow Jones industrial average .DJI rose 152.29 points, or 1.05 percent, to close at 14,719.46. The Standard & Poor's 500 Index .SPX gained 16.28 points, or 1.04 percent, to finish at 1,578.78. The Nasdaq Composite Index .IXIC advanced 35.78 points, or 1.11 percent, to end at 3,269.33.
Netflix Inc shares jumped 24.4 percent to $216.99 while Coach shot up 9.8 percent to $55.55. They were the S&P 500's two biggest percentage gainers.
Travelers Cos (TRV.N) helped lift the Dow, up 2.1 percent at $86.35 after the insurer posted earnings that topped expectations and boosted its dividend.
Earnings season has been largely positive, with more than 68.9 percent of S&P 500 companies that have reported results so far beating expectations, according to Thomson Reuters data. Since 1994, 63 percent have surpassed estimates on average, while the beat rate is 67 percent for the past four quarters.
"We are encouraged to see the market focusing on fundamentals, because we had been in a period where the macro trade was pretty much driving things - whatever the global macro event was or political event was seemed to be affecting the movement of the markets for a period of time," said Paul Mangus, head of equity research and strategy at Wells Fargo Private Bank in Charlotte, North Carolina.
The benchmark S&P 500 index has risen 2.4 percent over the past three sessions.
Analysts see earnings growth of 2.3 percent this quarter, up from expectations of 1.5 percent at the start of the month.
Housing stocks ranked among the best performers, after Barclays raised its rating on the homebuilding sector to "positive" from "neutral." The sector also got a lift from encouraging housing data, with U.S. new home sales up 1.5 percent in March.
The PHLX housing sector index .HGX rose 3.8 percent, led by a 9.3 percent gain in Toll Brothers (TOL.N) to $34.13. Barclays raised its recommendation on Toll Brothers' stock to an "overweight" rating as part of the firm's broader sector call.
Volume was active, with about 6.39 billion shares traded on the New York Stock Exchange, NYSE MKT and Nasdaq, slightly above the daily average of 6.38 billion. Advancing stocks outnumbered declining ones on the NYSE by a ratio of 4 to 1, while on the Nasdaq, more than three stocks rose for every one that fell. |
Amazing Ahri from League of Legends Cosplay by K Miyuko
K Miyuko cosplayed as Ahri, a popular character from the action strategy game League of Legends. She is known for her great cosplay, but this one actually made me scream "Awesome!" all across the office. |
Toledo, fueled by the high-screen action involving 6-11 reserve forward Luke Knapke and 6-4 Sanford, surged to a 58-48 advantage with 8:43 left in the second half. The Rockets built a 63-51 cushion by the 6:44 mark.
The RedHawks' full-court press helped them scramble back into it. Miami pulled within 65-61 with 1:55 left. Twenty seconds later, Miami missed two 3-point attempts, either of which could have cut the deficit to one.
Miami guard Nike Sibande drilled a deep, topside 3-pointer with 11 seconds left to finally cut the deficit to one -- 70-69. Coming out of a timeout, Miami fouled Sanford, who missed the first free throw and made the second.
Sibande, guarded closely by Sanford, missed a topside 3-pointer in the final two seconds. Toledo rebounded and the horn sounded. |
Jane’s TMA Blog
Fyn finds
Fyn is the Danish island which lies directly east of Jutland and has a gently rolling landscape punctuated by neat little villages and farms of remarkable cuteness and character. It reminded me very much of Drenthe in the Netherlands, only not flat.
Glavendrup
Among this scene of bucolic charm is Glavendrup (featured in The Megalithic European [TME] page 156).
It's a bit like Klæbek Høje, that we saw the day before, in that it started as a Bronze Age barrow to which the Vikings added a whole bunch of girly pink stones. First a large runestone was mounted on top of the barrow, and they also built a skibssætning megalithic longship, of the same pink sparkly Barbara Cartland type stones, with stripes and waves of quartz running through.
The wooded area had also been added to by modern stones, inscribed with the names of 20th century archaeologists who worked here. They looked OK, but reminded me too much of the stone memorials in the woods at Bergen-Belsen to thrill me. The wind chilled me and there was no chance of sketching here.
Magic at Marhøj
At the north east tip of Fyn is a little promentary on which can be found Marhøj (TME page 158), a particularly thrilling giant barrow. In a landscape shared by other fat, high, humpy høj, Marhøj is Queen.
Wading through the dark earth of the field littered with flints, we reached the monument and found the entrance to the passageway leading in is half way up the mound, rather than at ground level. Stooping very low (if you're tall this is almost a hands-and-knees-job) I squeezed down the 5 metre passage flanked with big flat stones to reach the main chamber which runs perpendicular to it.
The main passage was darker the dark. I got out the torch but it was unable to penetrate the blackness at all. I found a bit of candle and lit it. Then I found a tealight and lit that. And another and another and another until the whole chamber, 10ms long was illuminated by 26 tealights. It looked very hygge.
I sat down on the damp earth to inspect the chamber, smoke a cig and have a cuppa. It was vast: seven massive capstones formed the roof, all glistening in with wet in the candlelight making it as cosy as a fairy grotto. Moth scampered around with the tripod taking pictures and collecting more than 25 used tealights. It was cold in there – my breath was condensing - but it was out of the rain and the icy wind. It was fab.
We headed south from Marhøj (there is no other direction you can go on Fyn) to the east side of the island to see Lindeskov which is only given a tiny entry on page 157 of TME.
A complex at Lindeskov
We'd spotted another thing in James Dyer around Lindeskov and sought it out first: Lindeskov langdysser at 168ms (yes, metres!) the longest barrow in Denmark, and certainly the longest I've ever seen. It was never more than a metre high or 5ms wide and had regular kerbstones, giving it a visual rhythm not dissimilar to a millipede. That sounds a bit wanky but it was really like that.
While Moth fluttered around with the camera, I inspected the handy visitors' information board. To my surprise and delight, it showed a map with another six monuments nearby. I looked up in the direction indicted on the board towards a dolmen which I could just see through a hedge. I made a mental note of the map and we set out in search of what turned out to be the Lindeskov Complex: for this was indeed a complex: a series of interconnected monuments, each with clear sightlines to the next and no more than 400ms away at maximum from each other.
I drove up a muddy farm track marked 'Privat Vej' but we went on anyway, as on the map I'd seen it clearly stated public access.
We passed the dolmen standing alone in the field in the same lonely manner as Devil's Den and left the car at the copse at the top of the track and set off into the woodland, first coming across a trashed barrow with a couple of capstones in the middle. Just beyond the trees in a clearing lay two mighty monsters, Lindeskov 2 and Lindeskov 3 a couple of twin sister langdyssers lying directly next to each other and about the same length and width. Each of them had good kerbstones. L2 had a single stone cist and L3 had three good exposed chambers with capstones – looking very like Schimeres at Emmen in Drenthe.
Just 20 ms from the top end of L2 was L5 a rungdysse (round barrow) with kerbstones and an exposed central cist which would not have looked out of place in Scilly.
We felt quite chuffed with our 'discoveries'.
Finally we drove to Lindeskov as featured in TME, a langdysser right at the roadside.
It's a main road but as Denmark has so little traffic it didn't matter. The monument is correctly referred to as Lindeskov 6 and is dribblingly tasty. It's not particularly long, but has five chambers exposed on the top, four of which still have capstones. With its regular pink kerbstones and high, pointy supporting stones holding the capstones aloft it seems all dainty and floaty. |
Effect of changes in dietary sodium and potassium on blood pressure and cellular electrolyte handling in young normotensive subjects.
In a study on 22 normotensive male subjects, a change in dietary sodium intake from 29.6 +/- 6.0 to 332.5 +/- 13.9 mmol/day (mean +/- s.e.m.), over 7 days, was associated with a significant rise in supine and standing systolic blood pressure and a fall in sodium pump activity. Intracellular sodium remained constant, while intracellular potassium fell. These changes appeared to be reversed by the addition of potassium (96 mmol/day) to the high sodium diet. The 12 subjects with a family history of essential hypertension, as determined by measurement of parental blood pressure, did not differ in their response from those whose parents were normotensive. |
Who's ready for breakfast? With this wooden play food set, a young chef can prepare two golden-brown pancakes with all the fixings on a cooktop surface printed on the back of the corrugated storage box! Ingredients include chocolate chips, blueberries, bananas, and pats of butter. Cook them up on the wooden skillet and use the utensils to flip and slice. Self stick tabs on the food pieces make a satisfying crunch when sliced and also help the toppings stay on the pancakes! Serve up the pancakes on the printed thick paper placemat with a festive gingham design for hours of pretend-play fun.
Extension Activities: More Ways to Play and Learn:
Lay the circular topping pieces in a row and ask the child to count them with you.
Ask the child to sort the topping pieces (chocolate chips, blueberries, bananas, and butter) into two groups: circles and squares.
Place a selection of toppings on the play surface, with a different quantity of each type (1 banana piece, 2 blueberry pieces, etc.). Ask the child to identify the biggest group and the smallest group. Then help the child put the groups in order from biggest to smallest.
Connect the butter pieces into a single "stick." Ask the child to cut the stick into four equal pieces. Reconnect the pieces. Then challenge the child to cut the stick into two equal halves.
Use topping pieces to begin a pattern. (For instance, banana, blueberry, butter, banana, blueberry.) Ask the child to add the piece that will complete the pattern.
Place an order for one or two pancakes with specific toppings. Make your request aloud for younger children; for older children, write it on a slip of paper so the "chef" can read your order - just like in a real restaurant!
Ask the child to sort the toppings into three groups, with one type of ingredient in each group. Ask the child to count the individual groups, then count all the pieces together. |
Donald Sterling
BAILS On Interviews
with Barbara Walters, Anderson Cooper
5/2/2014 5:58 PM PDT BY TMZ STAFF
EXCLUSIVE
6:52 PM PDT. Donald Sterling talked to Walters and Cooper at length and decided NOT to go on camera, telling them he "wasn't prepared" ... sources familiar with the situation tell TMZ.
V. Stiviano did sit for a LONG interview with Walters, telling Babs she does NOT believe Sterling is a racist and saying the 15 minutes of audio were "taken out of context." She also said there was a 3rd person in the room when she recorded Sterling and he KNEW he was being recorded.
We're told poor Anderson walked away with zilch.
V was silent and back in visor mode (above) after talking to Babs -- but yes, she did take it off for the interview.
HERE'S THE RUNDOWN David Beckham Loses Control Of His Motorcycle In Hollywood Tom Hanks Blasts FIFA Over Women's World Cup Usain Bolt Uses Chris Brown & Drake To Impress Rihanna Country Legend Rips The NFL Over Half Time Show |
History Main / ImNotDoingThatAgain
* In ''Fanfic/{{Marionettes}}'', Trixie says this after [[spoiler:destroying Masquerade's [[PoweredArmor Puppeteer armor]] with a DeathOrGloryAttack that drained her mana engine so severely that she can barely stand and momentarily forgets she [[AnArmAndALeg only has three legs at the moment.]]]]
** Strong Bad says this in the WebAnimation/StrongBadEmail "after he removes his mask to prove that it is, in fact, his face, and that there's nothing but bone, muscle, and veins beneath it. Naturally, he does this while sitting in a high-backed chair, so the audience only sees a tiny, tiny sliver and hears the screaming.
to:
** Strong Bad says this in the WebAnimation/StrongBadEmail "after "the chair" after he removes his mask to prove that it is, in fact, his face, and that there's nothing but bone, muscle, and veins beneath it. Naturally, he does this while sitting in a high-backed chair, so the audience only sees a tiny, tiny sliver and hears the screaming.
* [[WebAnimation/HomestarRunner Strong Bad]] says this after he removes his mask to prove that it is, in fact, his face, and that there's nothing but bone, muscle, and veins beneath it. Naturally, he does this while sitting in a high-backed chair, so the audience only sees a tiny, tiny sliver and hears the screaming.
to:
* [[WebAnimation/HomestarRunner WebAnimation/HomestarRunner:** Strong Bad]] Bad says this after in the WebAnimation/StrongBadEmail "after he removes his mask to prove that it is, in fact, his face, and that there's nothing but bone, muscle, and veins beneath it. Naturally, he does this while sitting in a high-backed chair, so the audience only sees a tiny, tiny sliver and hears the screaming.** Done by Strong Sad in the email "radio", during Strong Bad's ImagineSpot to demonstrate how [[VocalDissonance radio announcers never sound how they look]]. Strong Bad temporarily turns the voice of timid and extremely soft-spoken Strong Sad into that of [[LargeHamRadio a obnoxiously loud and energetic morning radio host]]. Strong Sad pleads with Strong Bad "Don't you ever make me do that again!"
* In the ''WesternAnimation/StevenUniverse'' episode "Cheeseburger Backpack", after Steven inspires Amethyst to swing across a gravity vortex while holding the other two Crystal Gems, Pearl snaps at the two of them "Don't ever do that again!"
[[AC:Comic Books]]* In the ''Franchise/{{Tintin}}'' story "Explorers on the Moon", after a harrowing trip to the moon and back involving sabotage, stowaways, and near-asphyxiation, Captain Haddock reacts like this after Professor Calculus brings up the possibility of returning to the moon.-->'''Haddock:''' What?! Us go back there? To the moon? Me, go back to the moon?! May I be turned into a bollard, blistering barnacles, if I so much as set foot in your flying coffin again! Never, d'you hear? You interplanetary goat, you! Never!!
** And when the Flash finally [[IAmNotLeftHanded hits top speed]] to defeat the BigBad and the rest of the JusticeLeague pulls him from the brink, we get the page quote. Earlier in the same episode, this is his reaction to the way he took out his evil, Braniac-generated doppelganger (punching through its chest and vibrating until it exploded, knocking him for a loop in the process).
to:
** And when the Flash finally [[IAmNotLeftHanded hits top speed]] to defeat the BigBad and the rest of the JusticeLeague WesternAnimation/JusticeLeague pulls him from the brink, we get the page quote. Earlier in the same episode, this is his reaction to the way he took out his evil, Braniac-generated doppelganger (punching through its chest and vibrating until it exploded, knocking him for a loop in the process).
** In the second movie, when the team is escaping some military planes in their jet, Storm tries to shake them by doing a barrel roll. An ill-looking Wolverine asks her not to do that again, to which the normally wild teen John agrees.
* in PiratesOfTheCaribbean On Stranger Tides, [[CrazyAwesome Jack Sparrow]]'s response to blowing up a lighthouse (and nearly himself) is "Did everyone see that? Because I will NOT be doing it again!"
to:
* in PiratesOfTheCaribbean On Stranger Tides, In ''Film/PiratesOfTheCaribbeanOnStrangerTides'', [[CrazyAwesome Jack Sparrow]]'s response to blowing up a lighthouse (and nearly himself) is "Did everyone see that? Because I will NOT be doing it again!"
** Ax also used this StockPhrase ("I will not do this again") in a more dramatic, ShootTheDog context, when the plan involved him capturing Chapman and interrogating him in the ToThePain style for hours on end.** When the kids morph ants - the ant morph has some ''very'' disturbing side effects.** Cassie also says this when she leaves the Animorphs for a brief period, referring to a particularly grisly battle.
to:
** Ax also used this StockPhrase ("I will not do this again") in a more dramatic, dramatic ShootTheDog context, when the plan involved him capturing Chapman and interrogating him in the ToThePain style for hours on end.** When the kids morph ants - the ants--the ant morph has some ''very'' disturbing side effects.effects. Turns out, the termite morph has very similar effects. That's another one nobody's ever doing again.** Cassie also says this when she leaves the Animorphs for a brief period, referring to a particularly grisly battle.
* Jack Harkness casually drops this in while referring to [[MisterSeahorse pregnancy]] in the ''Series/{{Torchwood}}'' episode "Everything Changes".* In one episode of ''WKRPInCincinnati'' Herb gets talked into pretending to be gay and hitting on another guy. The attempt fails, and when he gets back: "I am ''never'' doing that again! I get enough rejection from ''women''!"* In episode five of ''Series/{{Sherlock}}'', during a typical 'bored Sherlock rant':-->'''Sherlock:''' It's either that, or Cluedo.\\
to:
* Jack Harkness Captain [[ExtremeOmnisexual Jack]] [[ReallyGetsAround Harkness]] casually drops this in while referring reference to [[MisterSeahorse pregnancy]] in the ''Series/{{Torchwood}}'' episode "Everything Changes".* In one episode of ''WKRPInCincinnati'' ''Series/WKRPInCincinnati'' Herb gets talked into pretending to be gay and hitting on another guy. The attempt fails, and when he gets back: "I am ''never'' doing that again! I get enough rejection from ''women''!"* In episode five of ''Series/{{Sherlock}}'', during a typical 'bored Sherlock rant':"bored Sherlock" rant:-->'''Sherlock:''' It's either that, that or Cluedo.''Cluedo''.\\
* In ''KatawaShoujo'', one H-scene in [[spoiler: Emi's route]] have her and Hisao [[spoiler: trying anal sex.]] It turns up they both find it uncomfortable and swore to never do it again.
to:
* In ''KatawaShoujo'', ''VisualNovel/KatawaShoujo'', one H-scene in [[spoiler: Emi's [[spoiler:Emi's route]] have has her and Hisao [[spoiler: trying [[spoiler:trying anal sex.]] sex]]. It turns up out that they both find it uncomfortable and swore swear to never do it again.
** At the beginning of ''VideoGame/EscapeFromMonkeyIsland'', pirates have invaded Guybrush's ship and tied him to the mast. Guybrush needs to kick over a blazer of coals and kick one onto a cannnon to sink the other ship. Instead, you can choose to kick one of the coals at the pirates offscreen, who retaliates by throwing a knife next to Guybrush's head. Quote Guybrush, "Better not try THAT again!"
to:
** At the beginning of ''VideoGame/EscapeFromMonkeyIsland'', pirates have invaded Guybrush's ship and tied him to the mast. Guybrush needs to kick over a blazer of coals and kick one onto a cannnon cannon to sink the other ship. Instead, you can choose to kick one of the coals at the pirates offscreen, off-screen, who retaliates by throwing a knife next to Guybrush's head. Quote Quoth Guybrush, "Better not try THAT again!"
* In a "Frogger" episode on ''SaturdaySupercade'', Frogger used his tongue to prevent a fatal accident. Unfortunately, the only thing he can latch onto is a cactus and afterward, his tongue is painfully perforated with cactus needles. Cue trope title.* In one ''WesternAnimation/JusticeLeague'' episode, ComicBook/{{Metamorpho}} [[DisneyDeath apparently sacrificed his life]] to stop a monster. Fortunately, Metamorpho is able to reconstitute himself with a satisified but weary comment, "I'm not doing that again."
to:
* In a "Frogger" episode on ''SaturdaySupercade'', ''WesternAnimation/SaturdaySupercade'', Frogger used his tongue to prevent a fatal accident. Unfortunately, the only thing he can latch onto is a cactus and and, afterward, his tongue is painfully perforated with cactus needles. Cue trope title.* In one ''WesternAnimation/JusticeLeague'' episode, ComicBook/{{Metamorpho}} [[DisneyDeath apparently sacrificed his life]] to stop a monster. Fortunately, Metamorpho is able to reconstitute himself with a satisified satisfied but weary comment, "I'm not doing that again."
* In the ''WesternAnimation/ChallengeOfTheGobots'' episode "Et Tu, Cy-Kill?" Leader-1 ends up having to fly in jet mode, at jet speeds, through a huge corridor filled with stone columns, dodging all of them. Afterward he [[TransformingMecha transforms]], falls to his knees, and says, "I couldn't do that twice."
to:
* In the ''WesternAnimation/ChallengeOfTheGobots'' episode "Et Tu, Cy-Kill?" Cy-Kill?", Leader-1 ends up having to fly in jet mode, at jet speeds, through a huge corridor filled with stone columns, dodging all of them. Afterward he [[TransformingMecha transforms]], falls to his knees, and says, "I couldn't do that twice."
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Random post
By the time you hear a sermon preached, there are words, illustrations and maybe even a rant or two that’s been left out.
This weekend, I preached from 1 Corinthians 12. We heard that one of the gifts God has given us, the church, is the gift of unity. The unity of God’s Church is unique. No other group of humans can experience this unity in the same way because God has brought us together.
I left out a quote I had been considering. In the end, it didn’t fit, exactly, what we were hearing. I’ll probably use it some time in the future.
In the mean time, it’s a great enough thought that you should hear it now.
I read The Turquoise Table this week. The book is about creating community. In our ever-connected but truly disconnected world, that can be hard to do. We have a hard time trusting others. Seeing others differently.
Writing about our need to deconstruct the walls we put up between each other, the author quoted another author, saying:
We are those people. The truth is, we are the others. Most of us are one paycheck, one divorce, one drug addicted kid, one mental health illness, one sexual assault, one drinking binge, one night of unprotected sex, or one affair away from being those people. The ones we don’t trust. The ones we pity. The ones we don’t let our kids play with. The ones bad things happen to. The ones we don’t want living next door.
(Emphasis mine)
Lord, with that reminder, help us, as much as it is possible on our part, to live at peace with everyone.
If you’re wondering how to get kids to read, it’s actually pretty simple. Have them watch adults who do. I don’t have to prove that. It’s been demonstrated forever.
But here’s the more difficult question: How do you get adults to read?
Parents expect their children to learn how to read the Bible, for example, but aren’t in the habit of reading it themselves. What I’ve learned is that the adults don’t read the Bible not because they don’t believe it’s important. They just don’t read anything.
That’s a problem.
Reading impacts so much of our life.
I didn’t always read. It’s only been in the last 15 years that I’ve actually been a reader. It was difficult for me for a long while. But I stuck with it. It’s been several years that I read at least 24 books a year. My goal is to double that, at some point.
So, here’s my advice if you don’t consider yourself a reader. This is going to be a novel approach–you might want to take notes. There are 3 things to remember:
Just do it. You’ll find it’s not that big a deal once you start.
Start small. Carve out 10 minutes each day to read. (That’s the same advice I give for starting to pray and read the Bible.)
Start smart. If you’re not used to reading, don’t start with a book about brain surgery, unless that interests you. Find something that you’re easily engaged with. Remember, the goal is to get used to reading.
And no, none of that is novel at all. It isn’t Rocket Science. They’re just words that need to be read.
You get-things-done-in-a-timely-manner people always make fun of us procrastinators. Yes, I am a procrastinator. In fact, I’m a Pro procrastinator.
One time in seminary, I decided to do an assignment early. It was a bit difficult to muster the right attitude to get it done. But I finished the paper about 10 days before it was due. I laughed about it and considered it a blessing from Baby Jesus.
Baby Jesus forgot to remind me to turn the paper in on time.
I lost a whole letter grade because it was late.
Since then I’ve learned that I’m a procrastinator and there’s nothing wrong with that. It’s how I work best. And my work gets done. And it gets done well.
I love CityAlight! I’ve listened to their albums and appreciate their ability (willingness) to create songs that are meant for congregations to sing together. The music is good and the writing is wonderful.
For through the law I died to the law, so that I might live to God. I have been crucified with Christ; and it is no longer I who live, but it is Christ who lives in me. And the life I now live in the flesh I live by faith in the Son of God, who loved me and gave himself for me.
-Galatians 2:19-20 |
/**
* Copyright Amazon.com, Inc. or its affiliates. All Rights Reserved.
* SPDX-License-Identifier: Apache-2.0.
*/
#pragma once
#include <aws/dynamodb/DynamoDB_EXPORTS.h>
#include <aws/core/utils/memory/stl/AWSString.h>
namespace Aws
{
namespace DynamoDB
{
namespace Model
{
enum class ReturnItemCollectionMetrics
{
NOT_SET,
SIZE,
NONE
};
namespace ReturnItemCollectionMetricsMapper
{
AWS_DYNAMODB_API ReturnItemCollectionMetrics GetReturnItemCollectionMetricsForName(const Aws::String& name);
AWS_DYNAMODB_API Aws::String GetNameForReturnItemCollectionMetrics(ReturnItemCollectionMetrics value);
} // namespace ReturnItemCollectionMetricsMapper
} // namespace Model
} // namespace DynamoDB
} // namespace Aws
|
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Hemimorphite, is a sorosilicatemineral which has been mined from days of old from the upper parts of zinc and leadores, chiefly associated with smithsonite. It was often assumed to be the same mineral and both were classed under the same name of calamine. In the second half of the 18th century it was discovered that there were two different minerals under the heading of calamine - a zinc carbonate and a zinc silicate, which often closely resembled each other.
The silicate was the more rare of the two, and was named hemimorphite because of the hemimorph development of its crystals. This unusual form, which is typical of only a few minerals, means that the crystals are terminated by dissimilar faces. Hemimorphite most commonly forms crystalline crusts and layers, also massive, granular, rounded and reniform aggregates, concentrically striated, or finely needle-shaped, fibrous or stalactitic. |
Curuguaty
Curuguaty (; originally called Villa de San Isidro Labrador de los Reyes Católicos de Curuguaty) is a city and a district in the Canindeyú Department of Paraguay, that was the 4th and last capital of Paraguay during the Paraguayan War in 1869-1870.
Toponimy
The meaning of the word “Curuguaty” is “place of the Curugua”, curugua (Latin: Cucurbita odorifera) being a plant very common in the area.
Geography
Canindeyú Department has a richness in flora and is surrounded by the Mbaracayú Mountains, which have an average altitude of 400 meters above ocean level. It is possible, in this place, to appreciate the biological diversity of the Atlantic Forest, Spanish: Mata atlántica.
Climate
In summer, the temperature reaches 39 °C and in winter drops to 0 °C. The average in the entire department is 21 °C. The precipitations are very frequent and abundant.
Demography
The city counts with a population of 65.310 inhabitants, 34.137 are men and 31.172 are women, according to the projections of the Statistics, Polls and Census General Direction. A great number of the inhabitants are originating from neighbouring Brazil.
History
Curuguaty was found on May 15, 1712, by Juan Gregorio de Bazán y Pedraza, with the name of “Villa de San Isidro Labrador de los Reyes Católicos de Curuguaty”, on the banks of the Curuguaty River.
In this city lived during the government of Dr. Francia, the founder and first dictator of Paraguay, in his exile for over 30 years, José Gervasio Artigas, the liberator of Uruguay. During the War against the Triple Alliance, the Marshall López declared Curuguaty as his last and the 4th capital of Paraguay and the Vice-President Domingo Francisco Sánchez Corvalán settled in the place. López settled his troops near Curuguaty on the banks of the Itandey Stream, when he was going towards the Amambay Cordillera, where the last battles would be fought during the war.
Since the early years of the new millennium landless peasants fight for their land, which was in part at least given in the past decades to influential and wealthy men and women of the political upper classes of Paraguay. The last clashes occurred in June 2012 and cost the lives of at least eleven peasants and six policemen.
Personalities
A martyr of the Paraguayan Independence, Mauricio José Troche, is a native of Curuguaty.
Economy
The population of Curuguaty dedicates mostly to the exploit of wood and yerba mate.
Tourism
Some touristic places are:
The Solar de Artigas, the house where lived Gervasio Artigas during the government of José Gaspar Rodríguez de Francia, with a park in his honour.
In the proximities of the city are several communities of natives as the Mbya Guaraní and Ache Guayaki.
In the Municipality, a Museum where some old artifacts from the time of the war are on display.
There are also beautiful forests and swamps, besides the Curuguaty River, that form the rural landscape.
How to get there
Curuguaty is located 240 kilometers from Asunción; the way of access is through Route No. III “Gral. Elizardo Aquino” and through Route No. X “Las Residentas”, which communicates the departments’ capital with Asunción. Also, the superhighway of Itaipu, communicates the city with Alto Paraná and Presidente Franco.
Reaching the city, a not paved detour to the left leads to Villa Ygatimí, Ypehú, Itanará and the Mbaracayú Forest National Reserve.
References
Geografía Ilustrada del Paraguay, Distribuidora Arami SRL; 2007. .
Geografía del Paraguay, Primera Edición 1999, Editorial Hispana Paraguay SRL.
External links
About the violence in July 2012
SENATUR
Category:Populated places in the Canindeyú Department
Category:Populated places established in 1712 |
Distinct lymph nodal sonographic characteristics in breast cancer patients at high risk for axillary metastases correlate with the final axillary stage.
The purpose of this study was to assess the clinical relevance, limitations and most common findings of axillary ultrasound and subsequent image-guided aspiration cytology in clinically node-negative breast cancer patients who are at high risk for axillary metastasis. Following institutional review board approval and Health Insurance Portability and Accountability Act (HIPAA) compliance, sonographic axillary surveys from 112 patients considered at high risk for axillary metastases were reviewed retrospectively for the following abnormal features: asymmetric cortical thickening/lobulations; loss or compression of the hyperechoic medullary region; absence of fatty hilum; abnormal lymph node shape; hypoechoic cortex; admixture of normal and abnormal appearing nodes; and increased peripheral blood flow. Patients with either normal or abnormal ultrasound exams, but negative cytology, underwent sentinel node mapping. Patients with abnormal ultrasound and positive cytology proceeded to complete axillary dissection. The number of positive nodes, the size of tumour deposits and the histological pattern of metastatic disease on the positive nodes were then correlated and compared with their corresponding sonographic abnormalities. Abnormalities related to the lymph node cortex were indicative of N1a disease. Features such as loss or compression of the hyperechoic medullary region, absence of fatty hilum, abnormal lymph node shape and increased peripheral blood flow were predictors of N2-3 disease. In conclusion, nodal sonographic characteristics of patients at high risk for metastases are useful predictors of tumour burden in the axilla. When combined with the results from aspiration cytology, these findings could modify the surgical approach to the axilla, eliminating the need for sentinel node mapping in a significant proportion of patients. |
What is Respite Care for the Homeless?
In essence it is a place that allows Hospitals to discharge a Homeless person on the day they are ready. Avoiding prolonged and unnecessary days in the hospital, and also allows a safe place for a Homeless patient to recuperate. Ultimately decreasing the risk of readmissions for the same diagnosis. |
Les amateurs de hockey attendent le 1er juillet et le derby des joueurs autonomes avec impatience. Pour les partisans de foot, c’est mardi que commence Noël en juillet.
À compter de mardi, et pour le prochain mois, la fenêtre de transfert estivale sera ouverte et tous les espoirs sont permis.
Comme la Major League Soccer (MLS) est l’une des rares ligues à ne pas fonctionner avec un calendrier hivernal, cette fenêtre arrive en plein cœur de la saison et c’est généralement l’occasion pour les clubs de fourbir leurs armes afin de faire une dernière poussée avant les séries éliminatoires.
Depuis plusieurs semaines, rumeurs et rêves s’entrecroisent sur les divers réseaux sociaux et ça sera comme ça dans l’attente d’un dénouement d’ici le prochain mois.
Et tout ça, c’est en espérant que l’Impact n’aura pas à revivre le même cauchemar que l’été dernier alors que l’attaquant Jimmy Briand, qui avait une entente de principe, a décidé de ne pas prendre l’avion qui devait l’emmener à Montréal pour signer son contrat pour des raisons qui demeurent encore nébuleuses et qui avaient à voir avec divers avantages matériels.
Serré
Les partisans de l’Impact qui espèrent un coup de circuit risquent d’être déçus. Le club a certainement besoin de renforts, mais il est coincé par le plafond salarial.
La MLS étant ce qu’elle est, on ne sait pas exactement quel genre de montant est disponible pour l’embauche d’un ou plusieurs nouveaux joueurs. Tout ce que l’on sait, c’est que le Bleu-Blanc-Noir a un peu plus de 11,5 M$ d’engagés en salaires cette saison.
Il faut dire que certains contrats assez lourds, comme ceux de Rudy Camacho (700 000 $) et Harry Novillo (550 000 $) qui sont réservistes, viennent handicaper l’équipe.
Ce n’est pas pour rien que Rémi Garde a laissé entendre qu’une acquisition par l’entremise du FC Bologne était sans doute ce qui serait le plus simple pour sa formation cet été.
Mais il y a certainement du renfort qui s’en vient puisque l’équipe a fait l’acquisition d’une place de joueur international des Rapids du Colorado, il y a deux semaines.
Le cas Piatti
Et en toile de fond, il y a toutes ces rumeurs de retour en Argentine pour Ignacio Piatti qui est sérieusement courtisé par le club Independiente.
Piatti est actuellement blessé au genou droit et ne sera pas de retour avant le mois prochain. S’il décidait de partir, l’Impact devrait le libérer gratuitement pour services rendus.
Mais Piatti est un homme loyal et il y a fort à parier qu’il voudra terminer la saison à Montréal pour aller au bout des choses, surtout qu’il a raté presque toute la saison jusqu’à maintenant.
Et s’il devait partir, ça changera drôlement les choses. Il y aura plus d’argent disponible, mais il y aura aussi un gros trou à combler sur l’aile gauche parce que pour le moment, Omar Browne et Orji Okwonkwo n’ont pas encore prouvé leur constance et peuvent continuer de se partager le travail à droite.
Besoins
Le besoin le plus criant du Bleu-Blanc-Noir est un attaquant de pointe capable de marquer sur une base régulière puisqu’en 21 matchs, Anthony Jackson-Hamel (3) et Maximiliano Urruti (1) n’ont inscrit que quatre buts au sein d’une attaque qui se retrouve dans la deuxième moitié de la MLS avec seulement 26 buts.
L’arrivée d’un attaquant pourrait aussi régler un autre problème criant, soit l’absence d’un milieu offensif créatif qui dynamisera l’attaque.
En effet, si un tel joueur s’amenait cet été, Rémi Garde pourrait alors replacer Maxi Urruti comme milieu axial. C’est d’ailleurs à cette position qu’il a joué l’essentiel de la saison 2018 à Dallas.
Et si on veut vraiment se blinder, on pourrait aller chercher un milieu défensif d’expérience pour prêter main-forte à Samuel Piette tout en permettant aux jeunes de continuer de prendre du galon sans trop leur mettre de pression sur les épaules.
Il y a donc du boulot qui attend Rémi Garde et le reste de personnel impliqué dans les décisions sportives du club.
POSSIBILITÉS ET RÊVE
Avec l’ouverture de la fenêtre de transfert viennent les rumeurs. Voici quelques noms qui ont été liés à l’Impact au cours des dernières semaines, de même qu’un souhait qui ne se réalisera sans doute pas.
Lassi Lappalainen
Le jeune ailier finlandais fait actuellement carrière avec le HJK Helsinki, mais on raconte qu’il est très courtisé par le Bologne FC parce qu’à seulement 20 ans, il présente un potentiel plus qu’intéressant. Si le club italien de Joey Saputo devait mettre la main sur Lappalainen, il semblerait qu’il serait ensuite prêté à l’Impact jusqu’à la fin de la saison. D’ailleurs, Rémi Garde n’a pas nié qu’une telle manœuvre pourrait survenir.
Samuel Mraz
C’est un attaquant slovaque de seulement 22 ans qui a fait ses débuts italiens avec Empoli la saison dernière. Mais voilà, le club a fini au dernier rang de la Série A et sera relégué à la Série B quand la nouvelle saison reprendra le mois prochain. La saison dernière, il a disputé 11 matchs en Série A avec Empoli et en Série B en prêt avec Crotone, et il a inscrit un but dans chacun des deux championnats. Selon certains médias italiens, il serait près de Montréal, mais ce n’est pas le buteur redoutable tant recherché.
Le rêve
Il y a de ces joueurs qu’on aimerait voir avec son équipe et qui, pour une raison ou une autre, n’en ont jamais fait partie. Kei Kamara est de ceux-là. Le grand attaquant de la Sierra Leone a toujours eu une bonne cote auprès des amateurs montréalais qui ont souvent réclamé son acquisition de la part de l’Impact. Kamara a souvent laissé entendre qu’il ne détesterait pas venir à Montréal, les Rapids sont derniers dans l’Ouest, ils ne vont nulle part et malgré tout, l’attaquant de 34 ans a déjà huit buts en poche, lui qui a marqué en moyenne 10,5 buts par année depuis la saison 2010. Il vient toutefois avec un prix de 750 000 $, mais il réglerait un gros problème et deviendrait un favori de la foule. On peut bien rêver! |
Q:
Скрытие контента в таблице
Всем привет есть таблица. Каждому блоку таблицы задан определенный процентный width который в сумме дает 100% для корректного отображения всего содержимого на разных экранах. Есть длинный заголовок часть которого я хочу скрыть следующим:
white-space: nowrap;
overflow: hidden;
text-overflow: ellipsis;
Это нужно для того что бы длинный заголовок оставался на 1 строке — но проблема в том что это правило не работает в таблице. Применив его содержимое растягивается на всю ширину и скрытия с многоточием не происходит. Подскажите где копать кто знает?
A:
Сделайте ячейку блочным элементом display: inline-block;
td {
border: solid;
width: 20%;
overflow: hidden;
display: inline-block;
text-overflow: ellipsis;
}
<table>
<tr>
<td>
aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
</td>
<td>
bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
</td>
</tr>
</table>
|
/* ###
* IP: GHIDRA
*
* Licensed under the Apache License, Version 2.0 (the "License");
* you may not use this file except in compliance with the License.
* You may obtain a copy of the License at
*
* http://www.apache.org/licenses/LICENSE-2.0
*
* Unless required by applicable law or agreed to in writing, software
* distributed under the License is distributed on an "AS IS" BASIS,
* WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
* See the License for the specific language governing permissions and
* limitations under the License.
*/
package ghidra.program.database.map;
import static org.junit.Assert.*;
import java.util.List;
import org.junit.Assert;
import org.junit.Test;
import ghidra.program.model.address.*;
import ghidra.program.model.lang.LanguageID;
import ghidra.program.model.listing.Program;
import ghidra.program.model.mem.Memory;
import ghidra.program.model.mem.MemoryConflictException;
import ghidra.util.task.TaskMonitorAdapter;
public class AddressMapDB64BitTest extends AbstractAddressMapDBTestClass {
private static final LanguageID LANGUAGE_64BIT = new LanguageID("sparc:BE:64:default");
/**
* Constructor for AddressMapTest.
* @param arg0
*/
public AddressMapDB64BitTest() {
super();
}
@Override
protected Program createTestProgram() throws Exception {
Program p = createProgram(LANGUAGE_64BIT);
boolean success = false;
int txId = p.startTransaction("Define blocks");
try {
AddressSpace space = p.getAddressFactory().getDefaultAddressSpace();
p.setImageBase(space.getAddress(0x1000000000L), true);
Memory mem = p.getMemory();
// Block1 is located within first chunk following image base (base #0 allocated)
mem.createUninitializedBlock("Block1", space.getAddress(0x2000000000L), 0x100000,
false);
try {
mem.createUninitializedBlock("Block2", space.getAddress(0xfffffd000L), 0x4000,
false);
Assert.fail("Expected MemoryConflictException");
}
catch (MemoryConflictException e) {
// Expected
}
try {
mem.createUninitializedBlock("Block2", space.getAddress(0xfffffffffff00000L),
0x100001, false);
Assert.fail("Expected AddressOverflowException");
}
catch (AddressOverflowException e) {
// Expected
}
// Block2 is at absolute end of space (base #1 allocated)
mem.createUninitializedBlock("Block2", space.getAddress(0xfffffffffff00000L), 0x100000,
false);
// Block3 spans two (2) memory chunks and spans transition between positive and negative offset values
// (base #2(end of block) and #3(start of block) allocated
mem.createInitializedBlock("Block3", space.getAddress(0x7ffffffffff00000L), 0x200000,
(byte) 0, TaskMonitorAdapter.DUMMY_MONITOR, false);
success = true;
}
finally {
p.endTransaction(txId, true);
if (!success) {
p.release(this);
}
}
return p;
}
@Test
public void testKeyRanges() {
List<KeyRange> keyRanges = addrMap.getKeyRanges(addr(0), addr(0xffffffffffffffffL), false);
assertEquals(4, keyRanges.size());
KeyRange kr = keyRanges.get(0);
System.out.println(
addrMap.decodeAddress(kr.minKey) + "->" + addrMap.decodeAddress(kr.maxKey));
assertEquals(addr(0x2000000000L), addrMap.decodeAddress(kr.minKey));
assertEquals(addr(0x20ffffffffL), addrMap.decodeAddress(kr.maxKey));
kr = keyRanges.get(1);
System.out.println(
addrMap.decodeAddress(kr.minKey) + "->" + addrMap.decodeAddress(kr.maxKey));
assertEquals(addr(0x7fffffff00000000L), addrMap.decodeAddress(kr.minKey));
assertEquals(addr(0x7fffffffffffffffL), addrMap.decodeAddress(kr.maxKey));
kr = keyRanges.get(2);
System.out.println(
addrMap.decodeAddress(kr.minKey) + "->" + addrMap.decodeAddress(kr.maxKey));
assertEquals(addr(0x8000000000000000L), addrMap.decodeAddress(kr.minKey));
assertEquals(addr(0x80000000ffffffffL), addrMap.decodeAddress(kr.maxKey));
kr = keyRanges.get(3);
System.out.println(
addrMap.decodeAddress(kr.minKey) + "->" + addrMap.decodeAddress(kr.maxKey));
assertEquals(addr(0x0ffffffff00000000L), addrMap.decodeAddress(kr.minKey));
assertEquals(addr(0x0ffffffffffffffffL), addrMap.decodeAddress(kr.maxKey));
}
@Test
public void testRelocatableAddress() {
Address addr = addr(0x1000000000L);
assertEquals(AddressMap.INVALID_ADDRESS_KEY, addrMap.getKey(addr, false));
int txId = program.startTransaction("New address region");
try {
// base #5 allocated
long key = addrMap.getKey(addr, true);
assertEquals(0x2000000400000000L, key);
assertEquals(addr, addrMap.decodeAddress(key));
}
finally {
program.endTransaction(txId, true);
}
addr = addr(0x2000001000L);
long key = addrMap.getKey(addr, false);
assertEquals(0x2000000000000000L + 0x1000, key);
assertEquals(addr, addrMap.decodeAddress(key));
addr = addr(0x7ffffffffff00000L);
key = addrMap.getKey(addr, false);
assertEquals(0x2000000200000000L + 0x0fff00000L, key);
assertEquals(addr, addrMap.decodeAddress(key));
addr = addr(0x8ffffffffff00000L);
assertEquals(AddressMap.INVALID_ADDRESS_KEY, addrMap.getKey(addr, false));
txId = program.startTransaction("New address region");
try {
key = addrMap.getKey(addr, true);
assertEquals(0x2000000500000000L + 0x0fff00000L, key);
assertEquals(addr, addrMap.decodeAddress(key));
}
finally {
program.endTransaction(txId, true);
}
}
@Test
public void testAbsoluteAddress() {
Address addr = addr(0x1000000000L);
long key = addrMap.getAbsoluteEncoding(addr, false);
assertEquals(0x1000000000000000L, key);
assertEquals(addr, addrMap.decodeAddress(key));
addr = addr(0x2000001000L);
assertEquals(AddressMap.INVALID_ADDRESS_KEY, addrMap.getAbsoluteEncoding(addr, false));
int txId = program.startTransaction("New address region");
try {
key = addrMap.getAbsoluteEncoding(addr, true);
assertEquals(0x1000000400000000L + 0x1000, key);
assertEquals(addr, addrMap.decodeAddress(key));
}
finally {
program.endTransaction(txId, true);
}
addr = addr(0x7fffffeffff00000L);
key = addrMap.getAbsoluteEncoding(addr, false);
assertEquals(0x1000000200000000L + 0x0fff00000L, key);
assertEquals(addr, addrMap.decodeAddress(key));
addr = addr(0x8ffffffffff00000L);
assertEquals(AddressMap.INVALID_ADDRESS_KEY, addrMap.getAbsoluteEncoding(addr, false));
txId = program.startTransaction("New address region");
try {
key = addrMap.getAbsoluteEncoding(addr, true);
assertEquals(0x1000000500000000L + 0x0fff00000L, key);
assertEquals(addr, addrMap.decodeAddress(key));
}
finally {
program.endTransaction(txId, true);
}
}
}
|
Sonographic identification and measurement of the epiphyseal ossification centers as markers of fetal gestational age.
This study was conducted to verify the predictive value of epiphyseal ossification center measurements in estimating gestational age. Women with singleton pregnancies of 30-40 weeks gestation (n = 377) were enrolled in this prospective study. The distal femoral, proximal tibial, and proximal humeral ossification centers were identified and measured. A nomogram of fetal bone development was created using the sum of the three diameters. Gestational age correlated well with the diameters of the distal femoral and the proximal tibial epiphyseal ossification centers but even better with the sum of the three ossification centers. Positive predictive values of the fetus having gestational age of at least 37 weeks when the sum of the three centers was 7, 11, and 13 mm were 82%, 94%, and 100%, respectively. A nomogram was created using the sum of the ossification centers for 30-40 weeks' gestational age. Ultrasonographic visualization of the epiphyses ossification centers may be a useful marker of fetal gestational age. |
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Follow Us
2017 Virginia Travel Guide and State Map
Shopping
Floyd Country Store
The Floyd Country Store is renowned as a place to experience authentic Appalachian music, and is home to a group of musicians, flatfoot dancers, and cloggers who are carrying on the tradition of their families who’d pass the time playing music and dancing together. Everywhere they could these folks would gather with their friends and families from their front porch to the neighbor’s kitchen. In the 1980’s folks in Floyd took to coming out to the General Store and began the Friday Night Jamboree tradition that continues today.
The Floyd Country Store is a real country store that is over 100 years old. You can’t miss the barrels of old-fashioned candy at the front of the store. If you explore further you can find everything from hand-dipped ice cream to hard-wearing bib overalls, and a great collection of hard-to-find old-time and bluegrass CDs and music accessories. Our menus feature good, homemade country food. The ice cream counter stays busy serving up shakes, sundaes and cones. The Friday Night Jamboree brings people each week to dance, enjoy and play gospel, old-time, and bluegrass music. See our website for the schedule. The store can host private events and tour groups, please call for details and availability. |
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<h1>Linear regression for <code>mids</code> object</h1>
<small class="dont-index">Source: <a href='https://github.com/amices/mice/blob/master/R/lm.R'><code>R/lm.R</code></a></small>
<div class="hidden name"><code>lm.mids.Rd</code></div>
</div>
<div class="ref-description">
<p>Applies <code><a href='https://rdrr.io/r/stats/lm.html'>lm()</a></code> to multiply imputed data set</p>
</div>
<pre class="usage"><span class='fu'>lm.mids</span>(<span class='no'>formula</span>, <span class='no'>data</span>, <span class='no'>...</span>)</pre>
<h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2>
<table class="ref-arguments">
<colgroup><col class="name" /><col class="desc" /></colgroup>
<tr>
<th>formula</th>
<td><p>a formula object, with the response on the left of a ~
operator, and the terms, separated by + operators, on the right. See the
documentation of <code><a href='https://rdrr.io/r/stats/lm.html'>lm</a></code> and <code><a href='https://rdrr.io/r/stats/formula.html'>formula</a></code> for details.</p></td>
</tr>
<tr>
<th>data</th>
<td><p>An object of type 'mids', which stands for 'multiply imputed data
set', typically created by a call to function <code><a href='mice.html'>mice()</a></code>.</p></td>
</tr>
<tr>
<th>...</th>
<td><p>Additional parameters passed to <code><a href='https://rdrr.io/r/stats/lm.html'>lm</a></code></p></td>
</tr>
</table>
<h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2>
<p>An objects of class <code>mira</code>, which stands for 'multiply imputed
repeated analysis'. This object contains <code>data$m</code> distinct
<code>lm.objects</code>, plus some descriptive information.</p>
<h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2>
<p>This function is included for backward compatibility with V1.0. The function
is superseded by <code><a href='with.mids.html'>with.mids</a></code>.</p>
<h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2>
<p>Van Buuren, S., Groothuis-Oudshoorn, K. (2011). <code>mice</code>:
Multivariate Imputation by Chained Equations in <code>R</code>. <em>Journal of
Statistical Software</em>, <b>45</b>(3), 1-67.
<a href='https://www.jstatsoft.org/v45/i03/'>https://www.jstatsoft.org/v45/i03/</a></p>
<h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2>
<div class='dont-index'><p><code><a href='https://rdrr.io/r/stats/lm.html'>lm</a></code>, <code><a href='mids-class.html'>mids</a></code>, <code><a href='mira-class.html'>mira</a></code></p></div>
<h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
<pre class="examples"><div class='input'><span class='no'>imp</span> <span class='kw'><-</span> <span class='fu'><a href='mice.html'>mice</a></span>(<span class='no'>nhanes</span>)</div><div class='output co'>#>
#> iter imp variable
#> 1 1 bmi hyp chl
#> 1 2 bmi hyp chl
#> 1 3 bmi hyp chl
#> 1 4 bmi hyp chl
#> 1 5 bmi hyp chl
#> 2 1 bmi hyp chl
#> 2 2 bmi hyp chl
#> 2 3 bmi hyp chl
#> 2 4 bmi hyp chl
#> 2 5 bmi hyp chl
#> 3 1 bmi hyp chl
#> 3 2 bmi hyp chl
#> 3 3 bmi hyp chl
#> 3 4 bmi hyp chl
#> 3 5 bmi hyp chl
#> 4 1 bmi hyp chl
#> 4 2 bmi hyp chl
#> 4 3 bmi hyp chl
#> 4 4 bmi hyp chl
#> 4 5 bmi hyp chl
#> 5 1 bmi hyp chl
#> 5 2 bmi hyp chl
#> 5 3 bmi hyp chl
#> 5 4 bmi hyp chl
#> 5 5 bmi hyp chl</div><div class='input'><span class='no'>fit</span> <span class='kw'><-</span> <span class='fu'>lm.mids</span>(<span class='no'>bmi</span> ~ <span class='no'>hyp</span> + <span class='no'>chl</span>, <span class='kw'>data</span> <span class='kw'>=</span> <span class='no'>imp</span>)</div><div class='output co'>#> <span class='warning'>Warning: Use with(imp, lm(yourmodel).</span></div><div class='input'><span class='no'>fit</span></div><div class='output co'>#> call :
#> lm.mids(formula = bmi ~ hyp + chl, data = imp)
#>
#> call1 :
#> mice(data = nhanes)
#>
#> nmis :
#> age bmi hyp chl
#> 0 9 8 10
#>
#> analyses :
#> [[1]]
#>
#> Call:
#> lm(formula = formula, data = complete(data, i))
#>
#> Coefficients:
#> (Intercept) hyp chl
#> 22.50144 -1.90019 0.03306
#>
#>
#> [[2]]
#>
#> Call:
#> lm(formula = formula, data = complete(data, i))
#>
#> Coefficients:
#> (Intercept) hyp chl
#> 23.48782 0.03300 0.01346
#>
#>
#> [[3]]
#>
#> Call:
#> lm(formula = formula, data = complete(data, i))
#>
#> Coefficients:
#> (Intercept) hyp chl
#> 20.8245 -0.4707 0.0305
#>
#>
#> [[4]]
#>
#> Call:
#> lm(formula = formula, data = complete(data, i))
#>
#> Coefficients:
#> (Intercept) hyp chl
#> 25.89571 -1.26785 0.01368
#>
#>
#> [[5]]
#>
#> Call:
#> lm(formula = formula, data = complete(data, i))
#>
#> Coefficients:
#> (Intercept) hyp chl
#> 21.18550 -2.00388 0.03847
#>
#>
#> </div></pre>
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Positions on Restoration and Management
of Wild Bison in Montana:
Whereas, the Montana Constitution requires that “the opportunity to harvest wild game is a heritage that shall forever be
preserved” and that “the legislature shall provide adequate remedies to prevent unreasonable depletion of natural resources’; and
whereas, there are no viable, year-round populations of wild bison in Montana; and
whereas, we do not leave bison to future generations, we leave the bison genome to future generations;
and
Therefore, the Gallatin Wildlife Association supports the following positions:
Wild bison in Montana:
1. Bison should again be recognized by Montana as valued, native, public trust wildlife, managed by Fish, Wildlife &
Parks, not by the Department of Livestock. Wild bison in Montana will provide recreational, commercial, ecological, scientific, esthetic and social values for Montanans.
2. Restoration should be emphasized within selected “Bison Management and Conservation Areas” having large units of mostly
contiguous public land.
3. In conforming to Montana law, bison herds can and should be managed in ways that respect private property
rights.
4. A wild bison herd must be large enough to maintain needed genetic diversity, and be influenced by a preponderance
of natural selection – so that its valuable wild characteristics are retained across generations. At least 1000 bison on at least 100 square miles of diverse habitat are needed.
5. The valuable ecological influences of wild bison upon native plants, animals, soils and microhydrology of
ecosystems should be expressed on at least a few large, ecologically diverse areas in Montana. The Greater Yellowstone Area and the C. M. Russell National Wildlife Refuge area offer the two
best opportunities for restoring wild bison in Montana, and probably within the USA.
6. Within the Greater Yellowstone Area, it is in the best interests of both bison restoration and the livestock industry to
maintain separation of bison and livestock during months when Brucella may be transmitted.
7. While it has never happened, transmission of Brucella from bison to livestock should be avoided. In achieving
this goal, we believe the most useful and efficient methods will emphasize livestock husbandry, including effective vaccinations, that will also protect livestock from elk-transmitted
Brucella. (Brucella from elk is the far more serious threat to livestock.)
8. Outside the Greater Yellowstone Area, wild bison should be restored with animals that are tested to be free of
Brucella.
9. In Montana, the numbers and distribution of restored wild bison should be managed with an emphasis on public and
Native American hunting, mostly applying the fair chase model. Traditional ways of big-game hunting may not suffice for bison management. Hunters should be dispersed in space and
time. Longer hunting seasons may be necessary to influence or control bison distribution at critical times. Licenses for specified sex/age classes of bison may be
necessary.
10. We oppose another completely fenced bison herd in Montana. However, strategically placed fencing that will
have little or no impact on other wildlife species, could be applied where needed on a limited site-specific basis. Where problem areas are few and small, bison should be fenced out, not
in. Other methods for controlling bison distribution may include culling of wandering bison, hazing and training bison, and developing attractive habitat on public land. We must learn how
to manage bison numbers and distribution in an adaptive manner.
11. Where wild bison are restored on public lands already permitted for use by private livestock, necessary changes
in livestock stocking rates, timing of use, or in types of livestock should be accomplished with the most fair and equitable of available opportunities. However, it is not appropriate for
private interests to deny a valuable public wildlife species from all the public lands.
Wild bison in Yellowstone National Park:
12. Intensive handling and interventions such as penning, feeding, vaccinating, and birth control of bison within
Yellowstone National Park, will diminish wildness and will not leave the wild bison genome unimpaired for the use and enjoyment of future generations of Americans, as required by federal
law.
13. Within Yellowstone National Park, most or all operations with bison at the Stevens Creek facility do not conform to the
mission of the Park Service. These operations are conducted according to laws and policies of Montana and should be the state’s responsibility.
14. Within the Yellowstone area, Brucella abortus is a naturalized species that can not be eradicated.
Coevolution of bison and Brucella will enhance bison resistance to the disease and may reduce virulence of Brucella. Within Yellowstone National Park, this coevolution should
proceed with minimal intervention that would weaken or replace the process. |
<?xml version="1.0" encoding="utf-8"?>
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<p style="text-align:right;"><a href="/doc/qcad/latest/reference/pt/index.php?page=scripts/Modify/Explode/doc/Explode">      </a></p>
<p style="font-style: italic;">Esta é uma tradução automática.</p>
<div class="nobreak">
<h2>Explodir</h2>
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<b>Barra de Ferramenta / Ícone:</b>
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using System;
namespace Server.Engines.Harvest
{
public class HarvestResource
{
private Type[] m_Types;
private double m_ReqSkill, m_MinSkill, m_MaxSkill;
private object m_SuccessMessage;
public Type[] Types{ get{ return m_Types; } set{ m_Types = value; } }
public double ReqSkill{ get{ return m_ReqSkill; } set{ m_ReqSkill = value; } }
public double MinSkill{ get{ return m_MinSkill; } set{ m_MinSkill = value; } }
public double MaxSkill{ get{ return m_MaxSkill; } set{ m_MaxSkill = value; } }
public object SuccessMessage{ get{ return m_SuccessMessage; } }
public void SendSuccessTo( Mobile m )
{
if ( m_SuccessMessage is int )
m.SendLocalizedMessage( (int)m_SuccessMessage );
else if ( m_SuccessMessage is string )
m.SendMessage( (string)m_SuccessMessage );
}
public HarvestResource( double reqSkill, double minSkill, double maxSkill, object message, params Type[] types )
{
m_ReqSkill = reqSkill;
m_MinSkill = minSkill;
m_MaxSkill = maxSkill;
m_Types = types;
m_SuccessMessage = message;
}
}
} |
Associated Press
While the Oklahoma City Thunder's dynamic duo of Russell Westbrook and Kevin Durant is no more, they reportedly have visions of a new one-two punch, featuring Westbrook and current Los Angeles Clippers forward Blake Griffin.
According to Adrian Wojnarowski of The Vertical, OKC is hoping to renegotiate Westbrook's contract to ensure he remains with the team through the 2017-18 season. In doing so, it aims to entice Griffin to sign with the organization in free agency next offseason.
Westbrook is set to become a free agent after the 2016-17 campaign, and after Durant signed with the Golden State Warriors, there has been plenty of speculation that Westbrook could opt to leave as well.
If the Thunder can convince Westbrook that another top-notch player is potentially on the way, however, it could be enough to at least delay the five-time All-Star's decision.
The 2015-16 season marked the first of Griffin's NBA career in which he wasn't named to the All-Star team, as he missed all but 35 games due to injury and a suspension levied against him after he punched a Clippers staffer and broke his hand.
Griffin still put up strong numbers with 21.4 points, 8.4 rebounds and 4.9 assists per game, but his name has come up in trade rumors often in recent years.
Video Play Button Videos you might like
The Clips have struggled to become championship contenders despite the immense talent on their roster, and that could lead to a shake-up that sees Griffin end up elsewhere next offseason.
Oklahoma City could be a great fit for him, as he would likely start alongside the defensive-minded Steven Adams following the trade of Serge Ibaka to the Orlando Magic.
If the Thunder can keep Westbrook, they will boast a dynamic backcourt that would also include Victor Oladipo, making them a potentially dangerous, exciting team that few will want to go up against in the Western Conference.
Griffin has yet to prove he can be a true winner at the NBA level despite his statistical output, but the Thunder need to make a high-impact move to get past the disappointment of losing Durant. Bringing in another perennial All-Star could pay dividends in terms of getting Westbrook to stay and returning to contention.
Follow @MikeChiari on Twitter. |
/*
* SonarQube
* Copyright (C) 2009-2020 SonarSource SA
* mailto:info AT sonarsource DOT com
*
* This program is free software; you can redistribute it and/or
* modify it under the terms of the GNU Lesser General Public
* License as published by the Free Software Foundation; either
* version 3 of the License, or (at your option) any later version.
*
* This program is distributed in the hope that it will be useful,
* but WITHOUT ANY WARRANTY; without even the implied warranty of
* MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU
* Lesser General Public License for more details.
*
* You should have received a copy of the GNU Lesser General Public License
* along with this program; if not, write to the Free Software Foundation,
* Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301, USA.
*/
package org.sonar.api.batch.sensor.rule;
import javax.annotation.Nullable;
import org.sonar.api.batch.rule.Severity;
import org.sonar.api.batch.sensor.Sensor;
import org.sonar.api.rules.RuleType;
/**
* Builder for a rule imported from an external rule engine by a {@link Sensor}. This allows to provide more metadata
* for rules associated to {@link org.sonar.api.batch.sensor.issue.ExternalIssue}.
* Don't forget to {@link #save()} after setting the fields.
*
* @since 7.4
*/
public interface NewAdHocRule {
/**
* Unique identifier of the external analyzer (e.g. eslint, pmd, ...)
*/
NewAdHocRule engineId(String engineId);
/**
* Unique rule identifier for a given {@link #engineId(String)}
*/
NewAdHocRule ruleId(String ruleId);
/**
* The name of the rule.
*/
NewAdHocRule name(String name);
/**
* The description of the rule.
*/
NewAdHocRule description(@Nullable String description);
/**
* Type of the rule.
*/
NewAdHocRule type(RuleType type);
/**
* Set the severity of the rule.
*/
NewAdHocRule severity(Severity severity);
/**
* Save the rule. There is almost no validation, except that no duplicated ad hoc rule keys are permitted.
*/
void save();
}
|
The next niche market for solar? Drones—yes, drones
By Alexis Madrigal
November 21, 2012
The idea that solar is a nice, soft technology that only liberals could love reaches back into the 1970s. It was there that the counterculture adopted solar energy as an alternative to the fossil fuels that dominated (and still dominate) the American energy mix. Solar became a symbol that Reaganites were happy to pillory in the 1980s, and that political divide continued into this century.
But it's not just geography that's changing the solar political picture. Solar power is increasingly useful to the Department of Defense. And that's a niche market that Alta Devices, which makes an ultra-efficient, ruggedized solar cell is hoping to make money. |
Importance of the cytochrome P450 monooxygenase CYP52 family for the sophorolipid-producing yeast Candida bombicola.
Three cytochrome P450 monooxygenases belonging to the CYP52 family were isolated from the genome of the sophorolipid-producing yeast Candida bombicola using degenerate PCR and genomic walking. One gene displayed high identity with the CYP52E members and was classified into this group (CYP52E3), whereas the other genes belonged to new groups: CYP52M and CYP52N. CYP52E3 and CYP52N1 turned out to be of no relevance for sophorolipid production, but show clear upregulation when the yeast cells are grown on alkanes as the sole carbon source. On the other hand, CYP52M1 is clearly upregulated during sophorolipid synthesis and very likely takes part in sophorolipid formation. |
PulseInput="Bemeneti hangrögzítő (PulseAudio)"
PulseOutput="Kimeneti hangrögzítő (PulseAudio)"
Device="Eszköz"
|
Effect of aflatoxin B1, benzo[a]pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells.
The increasing number of man-made chemicals in the environment that may pose a carcinogenic risk highlights the need for developing reliable time- and cost-effective approaches for carcinogen detection and identification. To address this issue, we investigated the utility of high-throughput microarray gene expression and next-generation genome-wide DNA methylation sequencing for the in vitro identification of genotoxic and non-genotoxic carcinogens. Terminally differentiated and metabolically competent human liver HepaRG cells were treated at minimally cytotoxic concentrations of (i) the genotoxic human liver carcinogen aflatoxin B1 (AFB1) and its structural non-carcinogenic analog aflatoxin B2 (AFB2); (ii) the genotoxic human lung carcinogen benzo[a]pyrene (B[a]P) and its non-carcinogenic isomer benzo[e]pyrene (B[e]P); and (iii) the non-genotoxic liver carcinogen methapyrilene for 72 h and transcriptomic and DNA methylation profiles were examined. Treatment of HepaRG cells with the liver carcinogens AFB1 and methapyrilene generated distinct gene-expression profiles, whereas B[a]P had only a slight effect on gene expression. In contrast to transcriptomic alterations, treatment of HepaRG cells with the carcinogenic and non-carcinogenic chemicals resulted in profound changes in the DNA methylation footprint; however, the correlation between gene-specific DNA methylation and gene expression changes was minimal. Among the carcinogen-altered genes, transferrin (TF) emerged as sensitive marker for an initial screening of chemicals for their potential liver carcinogenicity. Potential liver carcinogens (i.e., chemicals causing altered TF gene expression) could then be subjected to gene-expression analyses to differentiate genotoxic from non-genotoxic liver carcinogens. This approach may substantially enhance the identification and assessment of potential liver carcinogens. |
Airs is a bootleg shop in Nishi Shinjuku, a 'must go to' for any serious music fan. From the pics that cover the walls throughout the store you can guess that some people may even end up buying their own work!
Saturday, November 17, 2007
Friday, November 16, 2007
..is a comedian on a show called "Enta no Kamisama" (the gods of entertainment). He's the guy that does the presentation style sketches, really funny stuff. He's also married to the very desirable Fujiwara Norika! Here's another favorite (with subs):
Every weekend on koen dori, loads of wanna-be idols line the streets and footpaths to perform. Otaku (nerdy JP guys) take advantage of this opportunity by crowding around them and filling their memory cards with.. memories??
Tuesday, November 6, 2007
This is a term that Japanese people use towards foreigners in Japan when they behave disrespectfully. If there was ever a need to give an example of this term, I would show this video. I can't imagine Japanese getting away with this in a western country..
Thursday, November 1, 2007
Last Friday the media went mad once again over the shamed boxer. Daiki, his trainer and his brother attended a press conference in which they publicy apologised for their errant behaviour in the recent title fight, and also announced their father's retirement from the sport (he had been banned for life anyway..). These pictures were taken by Andy McGovern at the press conference before the fateful bout.
Seated at the press conference is the Japan Boxing Commissioner Yasukochi, Kameda, and his trainer Kaneishi.
Saturday, October 27, 2007
Ikimono Gakari is a bit of a shooting star here at the moment, she's on a massive nation wide tour and has a lucrative tie in with AU for her new single. I probably wouldn't know her from a bar of soap but for the fact that my buddy (and sometime Shirts drummer) Tak is drumming for her on her tour. Tak had a break between TV show tapings yesterday and came over and programmed some drums for the upcoming Shirts shows, and at some stage showed me this youtube vid that they had taped for some music TV show last Monday.
Nova has officially filed for bankrupcy. Needless to say there are many disgruntled students that forked out thousands for lessons that will not be taught. As teachers many years ago, we used to hate how the staff were trained to sell people dreams that weren't generally attainable ie. english conversation proficiency, they would easily slip into sociopath sales mode and put some unemployed dilbert into debt to get their precious branch numbers up. Not all staff were that blatantly heartless, just most... Around 4,400 english teachers have also found themselves unemployed and unpaid. There's a great (unfortunately unembeddable) NHK news item from yesterday here, and of all the crappy anti-Nova blog art being posted on Let's Japan etc. the only mildly humourous (and barely postworthy) were these:
Like so many others, I came to Japan to work as an english conversation instructor for what was then the biggest employer of foreign nationals in Japan, Nova. There were evident dodgy business practices, and daily frustrations with administration, but for my 2.5 years that I worked there, I learned a lot and had a great time. Seems that the bubble has really burst for them now, even my old school has closed.. :(
This video was from a month or two ago but the most recent rumblings have included: sudden school closures nationwide, the co-founder and highest level foreigner resigning, the losing of ALT dispatch contracts, teachers salaries being withheld and in some cases, rent not being paid on their apartments to the point where they are being evicted etc etc..
Thursday, October 18, 2007
'Daiki drama' continued yesterday when the disgraced boxer appeared at a press conference, supposedly held to enable his public apology. With his head shaved and missing his trademark dark glasses, he didn't actually say anything, but merely sat with head bowed for the short time he was in attendance. All of a sudden he appeared to have passed out, and was quickly helped to his feet (by his a couple of his minions) and led away to the kind of paparazzi flash explosions that only a Britney or a Lindsay could truly love.
Tuesday, October 16, 2007
Daiki Kameda is a Japanese professional boxer in the flyweight division. On October 11 2007, Kameda lost to Daisuke Naito, the reigning WBC flyweight champion. Despite making comments before the match that he will commit seppuku if he lost, his manager has confirmed that he will not. Towards the end of the bout, much to everyones surprise, he suddenly picked up opponent. This unusual act earnt him a suspension by the Japan Boxing Commission for one year and has fuelled a media frenzy which has seen virtually every major Japanese network constantly both replaying the act, and discussing it at length. Kameda has made it his custom to sing a song for the audience after each of his victories, needless to say, he didn't sing after this one..
This photo is by my buddy Andrew McGovern, who was shooting the fight. Check out more of his work here.
This is officially the most time consuming post I have ever made.. >_<
Thursday, October 4, 2007
Tuesday, October 2, 2007
Sawajiri is regarded as a notorious actress in Japan. At the press conference for her new film Closed Note, she looked pretty darn unhappy. When reporters asked her questions, she barely responded. She is called "the Queen" and "Erika-sama" because she is infamous for her selfish behavior. Most of the Japanese media treated her impolite and arrogant manner as top news! |
Faced with deploying a Macintosh network of dozens, hundreds, or even thousands of computers? Imaging your systems can help. Imaging saves you time and gives your users a consistent experience at every workstation. Sean Colins has been performing system admin tasks like imaging for nearly twenty years. Here, he shares his techniques for creating a master image you can deploy throughout your organization. These include restoring a Mac to a standard configuration, with or without a network; one-to-one deployments; building a portable hard drive that will help you troubleshoot issues on the go; rebooting troubled systems over the network; and adopting a modular workflow that will save you time building masters.Topics include:* Exploring the monolithic and modular imaging methodologies* Working with Fusion Drives and Recovery partitions* Ensuring physical security and installing a firmware password* Choosing source hardware* Installing apps* Building a complete monolithic master for imaging* Deploying apps and accounts in a modular master system* Building a base master* Performing hard-drive-to-hard-drive imaging* Exploring VLANs* Performing network-to-network imaging* Deploying using NetInstall or DeployStudio across a network |
import { commands, env, window } from 'vscode';
import { GistCommands } from '../extension-commands';
const createConfirmation: CommandInitializer = (
_config: Configuration,
services: Services,
utils: Utils
): [Command, CommandFn] => {
const { insights, logger } = services;
const command = GistCommands.CreateConfirmation;
enum CommandActions {
OpenInBrowser = 'Open in Browser',
CopyGistURL = 'Copy Gist URL to Clipboard'
}
const commandFn = async (gist: Gist): Promise<void> => {
try {
const { url } = gist;
logger.info(`Now presenting ${gist.description}`);
const selection = await window.showInformationMessage(
'Gist Created',
{ title: CommandActions.OpenInBrowser },
{ title: CommandActions.CopyGistURL }
);
if (!selection) {
logger.info('User dismissed "Gist Created" dialog without action');
return;
}
if (selection.title === CommandActions.OpenInBrowser) {
commands.executeCommand(GistCommands.OpenInBrowser, gist);
logger.info('Opening Gist in Browser');
insights.track(command, { type: 'browser' });
} else if (selection.title === CommandActions.CopyGistURL) {
env.clipboard.writeText(url);
logger.info('Copying Gist URL to Clipboard');
insights.track(command, { type: 'clipboard' });
}
} catch (err) {
const error: Error = err as Error;
logger.error(`${command} > ${error && error.message}`);
insights.exception(command, { message: error.message });
utils.notify.error(error.message);
}
};
return [command, commandFn];
};
export { createConfirmation };
|
Watch: Socialist Exceptionalism: “Americans Who Look To Government To Save Them… Fail To Realize It Was Government Who F%*ked Them”
Former British Prime Minister Margaret Thatcher once famously said that the problem with socialism is that you eventually run out of other people’s money. As of this writing our national debt is over $18 trillion and our unfunded long-term liabilities have been estimated to be as high as $200 trillion. Yet, despite this massive and unsustainable borrowing many Americans have been convinced that the party will continue for decades to come. And in the off chance our nation is ever faced with financial or economic crisis, our benevolent government will step in to save them – just like they did in 2008.
What most don’t realize, as highlighted in a new micro-documentary from Future Money Trends, is that it is the very government they have entrusted with their livelihoods and those of their children that is responsible for the disaster in the first place.
Americans for the most part suffer from Stockholm Syndrome, a medical diagnosis where the victim identifies with his or her attacker, even seeing reduced abuse as an act of kindness… Take, for example, Americans who got bailed out of their mortgage in 2009… At the core of the housing crisis is government. So the Americans who look to the government to save them and even gleefully thank the government for helping bail them out fail to realize it was the government who f%*ked them in the first place…
The reality is we know who the enemy is. They have given us a corrupted society where our children graduate as trained assembly line cubicle employees to the oligarchs in power.
The day of reckoning is upon us because debt financed socialism and corporatism isn’t working. It’s time for all thinking minds to opt out of the system. |
MELBOURNE has breathed a massive sigh of relief with prized youngster Jesse Hogan cleared of a serious foot injury.
The 20-year-old was sent for scans when he was unable to train after his foot was trod on during Thursday’s NAB Challenge loss to Fremantle.
MURPHY TO MISS AGAIN, MICK BACK
Melbourne football manager Josh Mahoney said the club was pleased with the results, but Hogan may miss this weekend’s NAB Challenge fixture against the Western Bulldogs in Ballarat.
“He had scans this morning which cleared him of any significant injury and he will be assessed to be available to play this week,” Mahoney told the AFL website.
Rumours began circling about Hogan’s fitness when he was absent from an open training session on Monday, given he was diagnosed with a back injury in similar circumstances on the eve of the 2014 season.
The power forward is yet to play a senior game in two seasons at Melbourne due to unavailability and injury, but he has put in an otherwise flawless pre-season and remains on track to debut for the club.
Originally published as Dee Hogan dodges serious foot injury |
Q:
Отправить скриншот! html2canvas
Доброго времени суток)
Моя задача отправить скрин элемента на другую страницу или на почту. Использую для этого html2canvas. Скрин сделать получилось, даже вставить его на эту же страницу. Но как отправить его куда то дальше не могу разобраться. Пытался через localStorage, но не вышло. Какие идеи есть?
html2canvas(document.getElementById("auto")).then(function(canvas) {
canvas.toDataURL();
document.getElementById("screen").appendChild(my_screen);`
A:
Воспользуйтесь упаковкой бинарных данных, которые Вы получаете методом toDataURL, в base64 и обратно при помощи встроенных в API браузера методов btoa() И atob().
То что вы раскодируете - просто подставьте в атрибут src тега img
let c = canvas.getContext('2d');
for(var i=0; i<10; i++) {
c.fillStyle = `hsl(${Math.random()*360},55%,55%)`;
c.fillRect(Math.random()*150, Math.random()*100, 50, 50);
}
function canvas2img() {
let str = btoa(canvas.toDataURL('png'));
console.log('str', str);
img.setAttribute('src', atob(str));
}
canvas, img {border:solid}
<canvas id="canvas" width=200 ></canvas>
<button onclick="canvas2img()" >canvas2img</button>
<img id="img">
|
The invention relates to a method of, and apparatus for, setting registration, with detection of the entry of a printing substrate into a printing machine having a number of color printing units, and calculation of the beginning of digital production of color separations to achieve an in-register position of the color separation prints on a printing substrate.
Printing colored illustrations, in particular color images, is carried out by a number of color separations being printed over one another. These are generally the colors yellow, magenta and cyan as well as black. If required, special colors are added. By overprinting these colors, all color combinations can be achieved, the quality of the prints depending significantly on the in-register overprinting of the color separations. In the case of digital printing processes, for example electrostatic printing processes, the maintenance of the register of the overprint is achieved by the image production devices being controlled in such a way that the color separations meet one another in-register when they are transferred to a printing substrate. This has to be set and, if necessary, readjusted during printing. Since the color separations are produced anew for each individual printed image, a setting or correction after each printing operation is possible.
U.S. Pat. No. 5,678,128 discloses a method and apparatus of the type mentioned at the beginning in which a sensor for detecting the entry of a printing substrate is arranged, and control is provided for the start of printing in the printing units in order to achieve maintenance of register. Since the sensor for detecting the printing substrates is located within the machine, there remains only a very short time in which to be able to perform the calculation before the first color separation has to be produced in order to be transferred to the printing substrate. On the one hand, this requires a high computer capacity and, on the other hand. it limits the speed of the printing operation. If coincidence of register is to be achieved, not only with respect to the image starts but also with respect to a number of or many defined areas on the color separations, then the necessary computer processing requirement is increased considerably. However, this is not possible in the short time available. Therefore, in the prior art, the possibilities of achieving high maintenance of register of the color separations are also limited.
The invention is therefore based on the object of developing a method and apparatus such that more time is available for calculating the setting values for the registration setting.
With respect to the method according to the invention, the object is achieved by the printing substrate being detected before it enters the printing machine, and, following this detection, the relative positions of the color separations being calculated, and precise detection of the leading edge of the printing substrate being performed as it enters the printing machine and made the basis for determining the starts of the production of the color separations, their relative positions having been precalculated.
With respect to the apparatus, the object is achieved in that a sensor arranged upstream of the printing machine detects the printing substrate before it enters the printing machine and gives a signal to the computer, whereupon the latter calculates the relative positions of the color separations, and in that the sensor arranged in the printing machine gives a signal to devices for determining the release of start signals for the production of the color separations, whose relative positions have been precalculated.
By the invention, therefore, the relatively high processing requirement on computing has been dealt with before a printing substrate enters the printing machine, and the values determined are kept ready in such a way that the allocation of the leading edge of the printing substrate which has entered the printing machine to the precalculated relative positions is all that is required. The allocation is carried out by releasing start signals for the production of the color separations in accordance with precalculated data. This is associated with a low processing requirement on computing, which can be managed in a short time. In this way, in spite of the high computing processing requirement as viewed overall, precise and rapid allocation of the printing substrate to the calculated values is possible. This makes it possible for the invention to achieve an accurate relative position of the color separations. By the invention, a higher print quality can thus be achieved, and the calculation of the register setting is no longer a bottleneck to increasing the printing speed.
The abovementioned advantages of the invention already show an effect if only a calculation of the relative position of the image starts of the color separations is carried out. However, the prolongation of the computing time according to the invention is particularly advantageous when the calculation of the relative positions of the color separations comprises both the image starts and the position of defined areas into which the color separations are subdivided. Here, these regions can be lines of image points in the color separations, or a defined number of lines of image points.
One refinement of the invention provides for the production of the electrostatic latent color separations in order to achieve coincidence of register to be calculated and made the basis for open-loop or closed-loop control. Another, particularly advantageous refinement provides for the positions of the production of the color separations to be coordinated in relation to their points of transfer to the printing substrate in order to achieve coincidence of register, and with the paths of the printing substrate and up to the points of transfer. The second embodiment has the advantage that errors which result from the time/position assignment, for example from a time/distance or a time/angle assignment, are not included in the calculation. In this way, more exact open-loop or closed-loop control is achieved, and therefore a higher maintenance of register and better printing quality.
The apparatus can be developed further in such a way that it is capable of implementing all the aforementioned method features. In this regard, the following refinements of the apparatus are advantageous:
Provision is expediently made for the computer to be loaded with data for the relative position of the carrier elements for the color separations and a substrate carrier and performs a calculation which, with respect to the relative positions of the color separations, gives the image starts and the position of the defined areas into which the color separations are subdivided, and controls the equipment for the production of the color separations on this basis. The data for the relative position of the carrier elements and a substrate carrier can be obtained in various ways. These may be distance/time data relating to the elements which carry images or substrates, or it is possible to provide position data which relate to these elements and are assigned to one another. It is also possible to input calibration tables with appropriate values from experience, which can be assigned to various positions of elements carrying images or substrates. Most expedient is a calibration table which is assigned to the carrier element with a surface for the production of the color separations, which is generally an image cylinder. For such an assignment, the angular positions of these elements can be used. The aforementioned data can also be determined by printing and detecting register marks.
For the last-mentioned purpose, it is proposed that the apparatus have at least one sensor for detecting a component of a color separation, and the computer is such that it coordinates the relative positions, detected in this way, of the individual color separations with one another in order to achieve coincidence of register and coordinates the relative position of the substrate carrier in order to position the print on the latter. Such defined components of a color separation may be the register marks but it is also possible to use other defined components, such as the limits of a picture.
An advantageous development of the apparatus provides for sensors for detecting angular positions of the elements that transfer color separations and the angular positions of the drive roller of the substrate carrier, the computer being such that it coordinates the angular positions of the elements that transfer color separations with one another in order to achieve coincidence of register, and coordinates the angular positions of the drive roller of the substrate carrier with the aforementioned angular positions. The aforementioned sensors can also be sensors for detecting paths, for example of register marks, or they may also be sensors which detect traveling times of elements carrying images or substrates. It is therefore possible for sensors for detecting the paths of the surfaces of the carrier elements, that is to say for example of the image cylinders, to be provided, and sensors can also be provided for detecting the paths of the surfaces of image transfer elements, for example of transfer cylinders. A sensor for detecting the path of the substrate carrier is also possible for the assignment of the printing substrates to the color separations. However, angular position transmitters are preferably provided as the sensors, and a calibration is carried out for the corresponding angular positions. |
ARTICLES ABOUT HAGERSTOWN POLICE DEPARTMENT BY DATE - PAGE 3
Police responded to a panic alarm at City Hall, at 1 E. Franklin St. The alarm was set off accidentally on Monday afternoon, according to a patrol clerk for the Hagerstown Police Department. Police responded to the alarm at 2:58 p.m.
The Hagerstown Police Department accepted four guns Saturday as part of Attorney General Doug Gansler's first statewide Gun Turn-In Day. Patrolman Kevin Brashears said residents turned in two handguns, a rifle and a pellet gun during the event, which was held locally from 11 a.m. to 4 p.m. at the Hagerstown Police Department. Brashears said the guns would be stored in gun lockers at police headquarters for the time being. The Maryland Attorney General's Office sponsored the event to give people a chance to safely dispose of any unwanted firearms.
Police are searching for a man who made off with an undisclosed amount of money in a robbery Friday afternoon at a Susquehanna Bank on Frederick Street in Hagerstown, according to a news release from the Hagerstown Police Department. The robbery at 940 Frederick St. occurred at 3:58 p.m., the release stated. According to police, upon entering the bank, the man handed a teller a note that demanded money. The man then fled the scene. The suspect is being described as a white male approximately 6-foot to 6-foot 2-inches in height, with a thin build, the release stated.
An armed robbery was reported at Universal Spirits at 33 E. Franklin St., Thursday night, according to a Washington County 911 spokesman. The robbery was reported at 10:36 p.m. and Hagerstown Police Department officers were investigating the incident, the spokesman said.
A Hagerstown man has been charged with reckless endangerment and other counts in connection with a shooting in which a man was wounded Monday evening in the 200 block of Jonathan Street, Hagerstown police said Tuesday. John Anthony Leonard IV, 18, of 133 Bethel St., also was charged with wearing and carrying a firearm, and possession of a firearm under 21, according to a Hagerstown Police Department news release. Officers said they were called Monday at 6:57 p.m. for a report of shots being fired to the rear of 225 Jonathan St. Responding officers found a man in the 100 block of Bethel Street who had a gunshot wound to his right leg. The man was taken to Meritus Medical Center east of Hagerstown, where medical personnel determined his wound was nonlife-threatening, police said.
A Hagerstown man is facing multiple criminal charges, including attempted criminal homicide and rape, after allegedly assaulting his ex-girlfriend in the Borough of Waynesboro home March 16. Charmar Desmond Drake, 23, of 425 Summit Ave., remains incarcerated in the Franklin County (Pa.) Jail, according to online court records. Waynesboro police allege Drake punched and strangled the woman, then threw nail polish remover on her face, hair and clothes while flicking a lighter and saying he was going to burn her. Drake forced the woman to have sexual intercourse, police wrote in an affidavit of probable cause.
In his former job as a probation officer, Daniel Monn helped parolees rejoin society. Now, the 28-year-old is training at the Hagerstown Community College Police Academy to take criminals off the streets. “The role has kind of switched, and now you're opening the door to the criminal justice system,” he said. Monn and 19 other recruits became part of the academy's inaugural class when courses started March 18. If Monn successfully completes the six-month program, he will be sworn in as a Hagerstown police officer.
Hagerstown's police chief said officers did not suspect foul play in the death of a 7-year-old boy who apparently drowned Thursday evening in the bathtub of his family's home at 425 Summit Ave. Police said Friday morning that the death of Nicodemus Kemp was being investigated by the Hagerstown Police Department, Washington County State's Attorney's Office and Washington County Child Advocacy Center. “There was nothing apparent at the scene that made it look like a suspicious death, but we're conducting a full investigation,” Police Chief Mark Holtzman said.
Hagerstown Police Department investigators are seeking the public's help in gathering information about two burglaries and an assault that occurred in March at the Washington Gardens apartment complex on Security Road, according to a police department news release. The crimes occurred March 5 just before 6:30 a.m., police said. A suspect is described as being a black male between 20 and 35 years old and having a slim or athletic build, police said. A substantial reward is being offered for information leading to the arrest of the person responsible for the crimes, police said. |
Designed Strategies and Adaptation of a Master Patient Index for Transgender Patients in a Tertiary Care Hospital.
Transgender people experience their gender identity as different from the sex assigned to them at birth and/or those listed on their legal identification. A Master Patient Index (MPI) is a centralized index of all patients in a health care system. The objective of this work was to describe the designed strategies and adapting of a MPI that contemplates transgender patient registration needs as regards as health and legal context. |
Programming Cells for Dynamic Assembly of Inorganic Nano-Objects with Spatiotemporal Control.
Programming living cells to organize inorganic nano-objects (NOs) in a spatiotemporally precise fashion would advance new techniques for creating ordered ensembles of NOs and new bio-abiotic hybrid materials with emerging functionalities. Bacterial cells often grow in cellular communities called biofilms. Here, a strategy is reported for programming dynamic biofilm formation for the synchronized assembly of discrete NOs or hetero-nanostructures on diverse interfaces in a dynamic, scalable, and hierarchical fashion. By engineering Escherichia coli to sense blue light and respond by producing biofilm curli fibers, biofilm formation is spatially controlled and the patterned NOs' assembly is simultaneously achieved. Diverse and complex fluorescent quantum dot patterns with a minimum patterning resolution of 100 µm are demonstrated. By temporally controlling the sequential addition of NOs into the culture, multilayered heterostructured thin films are fabricated through autonomous layer-by-layer assembly. It is demonstrated that biologically dynamic self-assembly can be used to advance a new repertoire of nanotechnologies and materials with increasing complexity that would be otherwise challenging to produce. |
The Delhi Subordinate Services Selection Board (DSSSB) has released the Teacher Additional selected candidates list. The supplementary result notice for the post of PRT (Teacher) for Delhi MCD Schools is available on the official website of DSSSB at https://dsssbonline.nic.in/. This post is for Delhi MCD Schools under the postcode of 16/17 and 01/18. Candidates are also being informed separately through SMS on their registered mobile number.
Important Dates:
Event
Dates
Uploading of necessary documents on the official website of DSSSB
2nd August till 11th August 2019
Number of selected and pending candidates
The DSSSB has selected a total of 125 candidates, out of which 28 candidates belong to the General category, 54 candidates belong to the OBC category, 12 to the SC and 35 to the ST Category. Also, a list of 19 candidates is prepared, whose candidature is kept pending for the reasons mentioned against their roll number.
On the homepage of the website, click on the link ‘DSSSB supplementary result Notice’.
Additional selected candidates’ list will be displayed.
Download the list and take a printout for possible future reference.
The DSSSB had released a notification mentioning 4,366 vacancies for the recruitment to the posts of Primary Teacher Municipal Corporation of Delhi on the official website. As per the notification, the candidates need to upload all the required documents from 2nd August till 11th August 2019. For further information regarding the recruitment of teachers, the candidates need to visit the official website of the authority frequently.
DSSSB Releases Teacher Additional Selected Candidate List for the Post of PRT was last modified: August 1st, 2019 |
Lack of peripheral sympathetic control of uterine blood flow during acute heat stress.
Peripheral alpha- and beta-adrenergic control of uterine blood flow (UBF) during acute heat stress of the gravid ewe was investigated. An electromagnetic blood flow probe was surgically implanted around the left miduterine artery and catheters inserted in the left carotid artery and right jugular vein in ewes between d 120 and 130 of gestation. Four or more days postsurgery, ewes were fitted with instruments to measure rectal temperature (Tr), heart rate (HR), respiratory rate (RR), blood pressure (BP) and UBF. One-half hour after instrument calibration, a 15-min thermoneutral control period was initiated with carotid artery blood samples taken at 5-min intervals for pH and PCO2 determinations. Ewes were then subjected to a heat challenge that reached 40 C at 2 h. All physiological data were recorded every 5 min as 1-min mean values. In seven experiments on five ewes, an alpha-adrenergic blocking drug, phenoxybenzamine (PB) was infused at 1 mg/min for 15 min subsequent to maximum depression of UBF. A beta-adrenergic blocking drug, propranolol (PR) was infused at .35 mg/min for 15 min in eight experiments on five ewes. Analysis of variance comparisons were made between the control period and heat stress infusion periods within the PB and PR experiments. Further comparisons were made between the start and 5, 10 or 15 min of PB or PR infusion in order to test drug effects during an acute heat stress. Rectal temperature HR, RR and arterial pH were higher (P less than .05) at the start of PR and PB infusions than during the thermoneutral control period.(ABSTRACT TRUNCATED AT 250 WORDS) |
Comorbid conditions and survival in unselected, newly diagnosed patients with chronic lymphocytic leukemia.
Little is known about the spectrum or frequency of comorbidities in patients with chronic lymphocytic leukemia (CLL). We investigated the prevalence and prognostic implications of comorbidities in patients with newly diagnosed CLL. Local/non-referred patients with CLL evaluated by a hematologist at Mayo Clinic within 1 year of diagnosis were eligible for this retrospective review. Of 1195 individuals evaluated for newly-diagnosed CLL between 1995 and 2006, 373 (31%) were local/non-referred. At diagnosis, 89% of these patients had one or more comorbidities, and 46% had at least one major comorbidity. Twenty-six percent of patients failed to meet NCI working group guidelines to participate in a clinical trial. On multi-factor analysis, Rai risk category (1.39 per each risk category increase; p < 0.0001) and age (1.056 per year increase; p < 0.0001) were the only factors associated with overall survival. We conclude that, although common, comorbid conditions are less important than age and stage in predicting prognosis in newly diagnosed patients with CLL. Clinical trials evaluating treatments that are designed to be tolerated by patients who do not meet traditional clinical trial eligibility criteria are needed. |
Serum 1alpha,25-dihydroxyvitamin D3 accumulates into the fracture callus during rat femoral fracture healing.
1,25-dihydroxyvitamin D3 (1,25(OH)2D3) is thought to be an important systemic factor in the fracture repair process, but the mechanism of action of 1,25(OH)2D3 has not been clearly defined. In this study, the role of 1,25(OH)2D3 in the fracture repair process was analyzed in a rat closed femoral fracture model. The plasma concentration of 1,25(OH)2D3 rapidly decreased on day 3 and continued to decrease to 10 days after fracture. We assessed whether this decrease was based on the accelerated degradation or retardation of the synthesis rate of 1,25(OH)2D3, from 25(OH)D3. After radiolabeled 3H-1,25(OH)2D3 or 3H-25(OH)D3 was injected i.v. into fractured or control (unfractured) rats, the concentrations of 25(OH)D3 and 1,25(OH)2D3 metabolites were measured by HPLC. The plasma concentrations of these radiolabeled metabolites in fractured group were similar to those in control rats early after operation. However, radioactivity in the femurs of fractured rats was higher than that of the control group. Furthermore, the radioactivity was concentrated in the callus of the fractured group analyzed by autoradiography. 1,25(OH)2D3 receptor gene expression was detected early after fracture and, additionally, both in the soft and hard callus on days 7 and 13 after fracture. These results showed that the rapid disappearance of 1,25(OH)2D3 in the early stages after fracture was not due to either increased degradation or decreased synthesis of 1,25(OH)2D3, but rather to increased consumption. Further, these results suggest the possibility that plasma 1,25(OH)2D3 becomes localized in the callus and may regulate cellular events in the process of fracture healing. |
A former CIA case officer who faced extradition to Italy for her alleged role in the rendition of a radical Egyptian Muslim cleric is now free after Trump administration officials intervened, according to a source close to the discussions.
CIA Director Mike Pompeo lobbied his counterparts in Portugal and Italy on behalf of Sabrina De Sousa who was convicted in absentia along with 25 other Americans after the post-9/11 rendition of an Egyptian cleric. He was later found guilty on terrorism charges. The CIA had no comment on the case.
The source said Friday that Pompeo worked behind the scenes to show that, on his watch, no CIA case officer would be left behind for executing a mission authorized at the highest levels of U.S. government.
De Sousa called her release "a huge and a very welcome development" in a statement Friday.
"I want to extend my deepest appreciation to the Trump administration for all their efforts on my behalf," she said. "Without their support I would be spending tonight in an Italian prison."
Former Rep. Pete Hoekstra, R-Mich., who was once the Republican chairman on the House Intelligence Committee and who lobbied hard on behalf of DeSousa, told Fox News, "The Obama administration and former CIA Director John Brennan abandoned De Sousa the last seven years, and in six weeks, the Trump team made her freedom possible."
A former senior intelligence official told Fox News, though, that “there was an extensive effort by the entire U.S. government to push the Italians to pardon these individuals,” and the allegation that the former CIA director abandoned U.S. personnel is unfounded.
The State Department declined to comment on several inquiries into the administration's role in De Sousa's release.
A White House official told Fox News on Friday the administration was "deeply disappointed in Ms. de Sousa’s conviction and sentence, and we, in conjunction with the State Department, followed her case closely and remained in touch."
"We appreciate the efforts of the Italian Government to challenge the prosecution before the Italian Constitutional Court," the official said. "The U.S. Government takes its obligation to assist U.S. citizens overseas seriously and we are pleased with the action the Italian Government decided to take."
De Sousa won a last-minute reprieve on Wednesday, hours before she was set to be extradited for the kidnapping and interrogation of the Egyptian cleric, whose name is Osama Mustapha Hassan Nasr. He is also known as Abu Omar.
The 61-year-old mother was working in Italy as an undercover CIA officer in 2003 when U.S. and Italian intelligence agents snatched Omar off the streets of Milan and transported him to his native Egypt for interrogation. There, he says, he was tortured.
The operation was part of the CIA's controversial "extraordinary rendition" program, implemented under President George W. Bush, which entailed taking terror suspects to countries where torture is allowed.
Omar -- who turned out to be a "nobody," according to De Sousa -- was held at an American military base in Germany before being flown to Cairo, Egypt. After interrogation, he was released from prison for lack of prosecutable evidence against him. The Italians, however, convicted him in absentia of "criminal association for the purposes of international terrorism" and sentenced him to six years in prison -- though he never served time.
De Sousa, meanwhile, said she was some 130 miles away in Madonna di Campiglio, Italy, chaperoning her son's school ski trip, on the day Omar was abducted -- and phone records obtained by Italian prosecutors corroborated that claim.
Still, Italy brought "broad charges" against her for a plot she says she had no direct part in.
The Italians also convicted in absentia 25 other Americans but several were since pardoned and none served time in prison.
De Sousa, who was born in India and holds both American and Portuguese passports, left the CIA in 2009 and moved to Portugal in April 2015 to be near family.
In October 2015, she was detained at Lisbon's airport on a European arrest warrant while attempting to travel to India. She was later released but ordered to remain in Portugal.
The series of events that followed amount to an international legal nightmare.
Italy first sought extradition of De Sousa with the guarantee of a retrial or appeal with new evidence, acknowledging she had been tried in absentia. Based on these guarantees, the Portuguese courts agreed to extradite.
But in June 2016, Italy sent Portugal a letter saying De Sousa's conviction was final, and no retrial would be granted. In a move that shocked De Sousa and others in the intelligence community, Portugal's high court ordered her immediate extradition.
Hoekstra, working on behalf of De Sousa, appealed to Trump administration officials for help.
On Tuesday, De Sousa received a "partial pardon" from Italian President Sergio Mattarella for her alleged part in the operation.
Under Italian law, the sentence reduction -- from four years to three -- meant De Sousa did not have to be extradited to Italy and imprisoned afterall. She was released Wednesday afternoon from a prison in Portugal.
"I had an arrest warrant issued against me 11 long years ago that prevented me from seeing members of my immediate family in Europe," De Sousa said in a statement to Fox News on Friday. "Finally, I can rest with the assurance there is no warrant hanging over my head."
"In six short weeks, the Trump administration has given me more hope and support than I ever received in the past eight years from the Obama Administration or the CIA, my former employer," she said. "I had feared that the country I signed up with in good faith to serve had abandoned me." |
Q:
Consider the equation $\,\,x^{2007}-1+x^{-2007}=0.\,$
I am stuck with the following problem:
Consider the equation $\,\,x^{2007}-1+x^{-2007}=0.\,$Let $\,m$ be the number of distinct complex non-real roots and $\,n$ be the number of distinct real roots of the above equation. Then $\,m-n\,$ is
1.$\,0$
2.$\,2006$
3.$\,2007$
4.$\,4014$
Can someone explain? Thanks in advance for your time.
My Attempt: $y=x^{2007}$ gives $y^2-y+1=0 \implies y=\frac12 \pm \frac{\sqrt 3i}{2}.\,\,$Now, I am not sure how to progress.
A:
HINT:
Putting $x^{2007}=a$ we get $a-1+\frac1a=0\iff a^2-a+1=0$
Observe that the discriminant of the last quadratic equation $<0$
Hence the values of $a$ are complex
As $x^{2007}(=a)$ is complex, so will be all the values of $x$
for if $x$ is real, so will be $x^n$ for any integer $n$
Do you know the number of roots of $$x^{2007}-1+x^{-2007}=0$$
|
PAGES
Wednesday, November 30, 2011
I am such a goober. I was laying in bed last night talking to Danny, when I realized that I didn't come up with the idea of finding cancer survivors. In fact, it was from a book that was given to me by a fellow brain cancer fighter, Jude. In the book (The Story Of Two: Fighting Serious Illness with an Attitude and an Advocate) was a story of a man who went to great lengths to survive his metastasized malignant melanoma. When I read that book, I realized that I should find more success stories. Without Jude's gift, who knows how long it would have taken me to figure out I could learn endless tricks from other cancer survivors. That's another wonderful thing about this blog, it has connected me with so many people that I never would have known. With my new friends, they bring with them knowledge, support, ideas, books, videos, doctor recommendations, researchers, and insurmountable hope. I'm so grateful for you! All of you.
Growing up in Friday Harbor, I was raised by a village. Now, I'm being healed by a village. Great things happen when great minds come together with a common cause. I can't thank all of you enough for helping me fight this. If you ever come across doctors, books, stories, treatments, research, please continue to send it my direction. I can't promise I'll try every outlet, and sometimes things fall through the cracks and I forget to follow through, but I'm working as hard as I can to explore each avenue. Thank you for continuing to help me stay up to date, and energized. This is quite a big challenge to take on, but like I've said in the past, I'm up for this - I can do it.
On another note, I want to share the late, but still exciting news of our friends Matt and AJ. Matt is Mr Movember, you might remember him from previous blogs. Anyway, during this crazy hectic month, Matt and AJ not only took on fundraising for my medical bills, but at the same time, their family grew! They welcomed twins. Here are a few photos that I stole from their Facebook pages :) Congrats you guys! And, welcome to the crazy world, Hazel and Owen.
3 comments:
I miss you and want you to know that I am thinking of you and praying that you are shrinking those toumor cells RIGHT NOW! The positive light you have on your life, and journey, inspire me every day to forget the small stuff and have the strength to tackle the hard stuff head-on. And most of the "hard stuff" isn't really even all that hard when put in perspective. Sometimes when something doesn't come easily it is easy to roll over and feel defeated. Thank you for reminding me, and all of us, to fight for our health and happiness.
I am so happy to hear that you are feeling better and back to running and reading. I think we all can take several of your lessons and apply them to our lives. Thank you for all that you are!Love,Sarah and Joey
An intriguing discussion is worth comment.I think that you need to publish more on this subject, it may not be a taboo subject but usually folks don't speak about such topics. To the next! Cheers!!My website - tattoo removal cream
Thought of The Day
The Fundraiser
I am so grateful for the GoFundMe account that our friends set up. They started it last fall, because I stopped my treatments because of lack of funds, and now, possibly because of my lapse, I have a brain surgery scheduled for March 3rd, Dan's birthday. We are hopeful that our neurosurgeon will be able to remove the majority of the three brain tumors. But having it be out of state, it's complicated financially, and we are very thankful for your donations, and your prayers!
Disclaimer
This blog is intended to be informational, and hopefully at times, educational. It represents solely my personal opinion. This blog and my opinion are not meant to be construed as professional medical advice for any specific person or patient or condition. Qualified and licensed healthcare professionals should be consulted before considering or using any therapeutic product or drugs discussed in this blog. Definitely work with doctors and specialists to find your own cocktail approach. Please don't take my word for anything, do your own research.
Thank You Note
I read every single comment I receive on the blog and I'm incredibly grateful to receive them! I don't always have the opportunity to respond to all of my comments and emails, but I appreciate the support very much. Thank you for checking out my blog. It's incredibly therapeutic for me, and I hope you find my story helpful. |
Leeward Caribbean Creole English
Leeward Caribbean Creole English, is an English-based creole language consisting of several varieties spoken on the islands of Antigua, Barbuda, Montserrat, Nevis, and Saint Kitts.
There are subtle differences in the language's usage by different speakers, and islanders often use it in combination with Standard English. The tendency to switch back and forth from Creole to Standard English often seems to correlate with the class status of the speaker. Persons of higher social status tend to switch between Standard English and Creole more readily, due to their more extensive formal education in the English-language school system. Creole usage is more common, and is less similar to Standard English, as speakers descend the socioeconomic ladder. This is an example of a Creole continuum.
Many Creole words are derived from English or African origins. The creole was formed when slaves owned by English planters imitated the English of their enslavers but pronounced it with their own inflections. This can be easily seen in phrases such as "", meaning "I am not going," or in "," presumably a cognate of "Ain't it?"
Vocabulary
Vocabulary is widely influenced by British vocabulary, due to centuries of association with Great Britain. Examples:
Bonnet refers to the hood of a car.
Chips refers to French Fries. However, fries is commonly used as well.
Form is used instead of the American high school grade. (7th Grade-1st Form; 11th Grade-5th Form)
Patty for flaky folded pastry, unlike the American patty, meaning hamburger patty.
Mongrel is used instead of the US mutt.
Biscuit is used instead of the US cookie.
However, in other cases the American form prevails over the British one, due to the islands' close proximity to the United States:
Apartment is used instead of the British flat.
Elevator instead of the British lift.
parking lot instead of car park.
Because of the influx of other Caribbean nationals to Antigua, due to natural migration and to the CSME, Antigua's everyday vocabulary is being influenced by Jamaican Creole, Bajan Creole, Guyanese Creole and Trinidadian Creole. This is even more common among the youth. Examples:
Yute and star meaning young man.
Breda (derived from Brethren and Partner) meaning close friend.
Sell off meaning excellent or very good.
Examples of un-derived words and phrases
pickney: child
pickanyegah: children
arue: collective address in the manner of "you all" or "y'all"
ah wah mek: why
chupit: stupid
smaddy: somebody
likkle: little
'ooman: woman
nyam: eat
sudden/subben/leff dee 'ooman sudden/leff dee 'ooman subben: can refer to an object or thing/ leave her things alone
cassy/cassie: a thorn, such as from a rosebush
tarll: no, not me, not at all
ah wah dee/da joke yah tarl/ah wah me ah see ya tarl: what in the world is going on?
leh meh lone: leave me alone
ah good/tek dat/ah baay/inna ya battum ho'al: that's good for you/take that
tap lie: stop lying
tap ya chupitniss: stop being silly
ah true/choo: it's the truth
ahnna true/choo: it's not true
look yah: look here
look day: look there
kum ya: come here
a fu you: Is it yours?
move from dey: get away from there
ah wat a gwaan/ wa gwaan: what's going on?
luk day: look there!
ah huffa daag dat?: whose dog is that?
a fu you ee fah?: is it yours?
e dutty: it's dirty!
dadday: that
day'ya: there
me nuh eeben know way dadday day: I don't know where it is.
gyal: girl
atta: at (Example: me guh laff atta you; I am laughing at you)
naal: not (Me naal do um; I am not doing that)
dung: down (Bredda man, kuum dung fram ahffa pan tappa up day; Hey, get down!)
yaad: (my, her, his) house (She ah go day'ya she yaad; She's going home.)
min: used to indicate the past tense of a verb (example: me min nyam; I ate | Ya min cook; Did you cook? | She min day'ya sleep, She slept.)
dun: strictly used to tell that something has finished (E dun?; Is it finished? | Ya dun?; Are you finished?)
siddung: sit down
git up: get up
tun rung: turn around
tun um ahn: Switch it on (Example: Tun de light ahn; Switch on the lights)
tun um ahf: Switch it off
gwaan/gwaan head: go ahead
innaddy: in (de sudden innaddy bax; it's in the box)
cunchee: countryside (he libba cunchree; He lives in the countryside)
tung: town or city (usually referring to the country's capital; Example: Me ah go tung/Me a go'ah tung; In going into the city)
see you: see you later
jaq: used to show annoyance (see you jaq: See you later (with an attitude))
bruk: to break, broke (E bruk?; Did it break? | Muh bruk; I'm broke | She bruk um/She min bruk um; She broke it)
muh nuh nuh: I don't know
muh nuh; muh dun nuh: I know; I already know, I knew that already
Mek she nuh go find she own man: why does she not get a man of her own?
Knuckle: cheating ( something widely and frequently discussed on Antiguan Twitter)
Pronunciation
Antiguan is pronounced very similarly to Jamaican. This has led some to surmise that the slaves of these countries came from the same place in Africa. Below are a few ways in which some language blends are fused or changed completely.
"TR" as in 'Truck' is pronounced "CH", thus: 'Chruck.'
"DR" as in 'Dress' is pronounced" J", thus: 'Jess'
"TH" as in 'Them' is pronounced "D", thus: 'Dem'
"TH" as in 'Think' is pronounced "T", thus: 'Tink'
"WN" as in 'Down' is pronounced "NG", thus: 'Dung'
"V" as in 'Vex' is pronounced "B", thus: 'Bex'
Sometimes an ending "T" is left off and words such as 'Best' sound like 'Bess'. Expect sounds like 'Expeck'; and 'Left' sounds like 'Leff'.
Language use
Antiguan Creole is used in almost every aspect of life in Antigua. In all schools, during class hours, it is required of students to speak Standard English. This policy is especially exercised in private owned schools. Most media and mainstream communication is written and spoken in Standard English, although Antiguan Creole is sometimes used humorously or as a way of identifying with the local public.
Use of Antiguan Creole varies depending on socio-economic class. In general, the higher and middle classes use it amongst friends and family but switch to Standard English in the public sphere. The lower class tend to use Antiguan Creole in almost every sector of life.
The Pronominal System
The pronominal system of Standard English has a four-way distinction of person, singular/plural, gender and nominative/objective. Some varieties of Antiguan Creole do not have the gender or nominative/objective distinction, though most do; but usefully, it does distinguish between the second person singular and plural (you).
I, me = me;
you, you (thou, thee) = yu;
he, him = he;
she, her = she;
we, us = ah-we;
they, them = dem;
To form the possessive form of the pronoun add "fu-" to the above. However, the pronoun "our" is an exception where we add "ar-".
my, mine = fu-mi;
your, yours (thy, thine) = fu-yu;
his, his = fu-he;
her, hers = fu-she;
our, ours = ah-we;
you all = ah-yu;
their, theirs = fu-dem
Example:
a fu-yu daag dat?, is that your dog?
a fu-yu daag dat day nuh, that is your dog.
See also
Nigerian Pidgin English
Krio language
References
Category:Languages of Antigua and Barbuda
Category:English-based pidgins and creoles
Category:Languages of the Caribbean
Category:Languages of the African diaspora |
Macron and Kagame meet to repair strained ties over Rwandan genocide
Information-technology pioneers win Nobel Physics Prize
The 2009 Nobel Prize in Physics went to three scientists for their pioneering works in fibre optics and for the invention of an imaging semi-conductor circuit which unleashed the information-technology revolution.
AFP - Charles Kao, Willard Boyle and George Smith won the 2009 Nobel Physics Prize Tuesday for pioneering "masters of light" work on fibre optics and semiconductors, the Nobel jury said.
The Hong Kong-based expert Kao and his two American counterparts were hailed for creating the two tools that helped unleash the Information Technology revolution of today.
"This year's Nobel Prize in Physics is awarded for two scientific achievements that have helped to shape the foundations of today's networked societies.
"They have created many practical innovations for everyday life and provided new tools for scientific exploration," it said.
One of them is the fibre-optic cable, which enables transmission of data at the speed of light, the Nobel jury said.
Kao, who has British nationality but has been based in Hong Kong, was awarded half of the prize for "groundbreaking achievements concerning the transmission of light in fibers for optical communication," it said.
"If we were to unravel all of the glass fibres that wind around the globe, we would get a single thread over one billion kilometres (600 million miles) long -- which is enough to encircle the globe more than 25,000 times -- and is increasing by thousands of kilometres (miles) every hour," it said.
Kao's discovery means that "text, music, images and video can be transferred around the globe in a split second," the jury said.
Boyle and Smith shared the other half of the prize for "the invention of an imaging semiconductor circuit -- the CCD sensor," or the charge-coupled device, which is the "electronic eye" of the digital camera.
The CCD sensor, invented in 1969, "revolutioniseded photography, as light could be now captured electronically instead of on film."
CCD technology is also used in many medical applications, such as imaging the inside of the human body, both for diagnostics and for microsurgery.
Last year, the prize went to Makoto Kobayashi and Toshihide Maskawa of Japan and Yoichiro Nambu of the United States for groundbreaking theoretical work on fundamental particles called quarks.
On Monday, Australian-American scientist Elizabeth Blackburn and Carol Greider and Jack Szostak of the United States won the Nobel Medicine Prize for identifying a key molecular switch in cellular ageing.
The Chemistry Prize laureates will be named on Wednesday, followed by the Literature Prize on Thursday and the Peace Prize on Friday. The Economics Prize will wrap up the awards on Monday, October 12.
The Nobel prizes, founded by Swedish industrialist Alfred Nobel, were first awarded in 1901.
Nobel, the inventor of dynamite, died childless in 1896, dedicating his vast fortune to create "prizes to those who, during the preceding year, shall have conferred the greatest benefit on mankind."
Laureates receive a gold medal, a diploma and 10 million Swedish kronor (1.42 million dollars, 980,000 euros) which can be split between up to three winners per prize.
The formal awarding of the prizes will take place at gala ceremonies in Stockholm and Oslo on December 10. |
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Q:
EXCEPT & INTERSECT: Purpose of Passive Projection in Logical Plan
The following EXCEPT query produces a logical plan with a seemingly purposeless projection. This also occurs for INTERSECT.
What is the purpose of the projection? e.g. Is there a different EXCEPT query where the outer projection would specify something?
Query:
use AdventureWorks2017
select p.ProductId
from Production.Product as p
except
select pinv.ProductID
from Production.ProductInventory as pinv
option (recompile, querytraceon 8605, querytraceon 3604)
Converted Tree:
LogOp_Select
LogOp_GbAgg OUT(QCOL: [p].ProductID,) BY(QCOL: [p].ProductID,)
LogOp_Project -- << ?? PASSIVE PROJECTION ??
LogOp_Project
LogOp_Get TBL: Production.Product(alias TBL: p) Production.Product TableID=482100758 TableReferenceID=0 IsRow: COL: IsBaseRow1000
AncOp_PrjList
AncOp_PrjList
AncOp_PrjList
ScaOp_Exists
LogOp_Select
LogOp_Project
LogOp_Get TBL: Production.ProductInventory(alias TBL: pinv) Production.ProductInventory TableID=914102297 TableReferenceID=0 IsRow: COL: IsBaseRow1001
AncOp_PrjList
ScaOp_Comp x_cmpEq
ScaOp_Identifier QCOL: [p].ProductID
ScaOp_Identifier QCOL: [pinv].ProductID
A:
There are various things we do inside the query optimizer that don't really have a reason that we can explain externally. The projects you see in the optimizer eventually get rewritten at the end of the optimizer to "flatten" the expressions. So, the optimizer has things in the search that are part of how the code is implemented that may introduce extra projects that don't really do anything functionally but do allow us to stitch things together where one subtree was created in one part of the optimizer but is used later in a place where it was not originally intended. There are some physical implementation details that can cause this to happen. None of them matter for users in terms of plan quality (in almost any case - we have done work to make these not matter in the search).
So, I'd just wave my hand and say "you don't need to see his identification. He can go about his business. Move along" ;).
A:
I don't have a fully satisfying answer to this, but DISTINCT is translated to a project plus group-by aggregate.
Both EXCEPT and INTERSECT come with an implied DISTINCT on the first table expression. It is this DISTINCT that results in the 'blank' project in the tree. It is harmless.
If you write a DISTINCT as the equivalent GROUP BY, you don't see the blank project. The project appears after the aggregate:
SELECT DISTINCT P.ProductID
FROM Production.Product AS P
OPTION (QUERYTRACEON 3604, QUERYTRACEON 8605);
LogOp_GbAgg OUT(QCOL: [P].ProductID,) BY(QCOL: [P].ProductID,)
LogOp_Project
LogOp_Project QCOL: [P].ProductID
LogOp_Get TBL: Production.Product(alias TBL: P)
AncOp_PrjList
AncOp_PrjList
AncOp_PrjList
SELECT P.ProductID
FROM Production.Product AS P
GROUP BY p.ProductID
OPTION (QUERYTRACEON 3604, QUERYTRACEON 8605);
LogOp_Project QCOL: [P].ProductID
LogOp_GbAgg OUT(QCOL: [P].ProductID,) BY(QCOL: [P].ProductID,)
LogOp_Project
LogOp_Get TBL: Production.Product(alias TBL: P)
AncOp_PrjList
AncOp_PrjList
AncOp_PrjList
|
577 F.2d 752
U. S.v.De Leon
No. 77-2645
United States Court of Appeals, Ninth Circuit
6/14/78
1
E.D.Cal.
AFFIRMED
|
of phylogenesis the ultimate origination of new biological forms during the
of the origin of biological information exposes a deficiency in the
Match 2 (1):
Reference (000556 .. 000590, of 13533):
Subject (008821 .. 008856, of 28080):
the situation starting in the 1970s many biologists began questioning its neo Darwinism s adequacy in explaining evolution Genetics might be adequate for explaining microevolution but microevolutionary changes in gene frequency were not seen as
Synthesis is a remarkable achievement However starting in the 1970s many biologists began questioning its adequacy in explaining evolution Genetics might be adequate for explaining microevolution but microevolutionary changes in gene frequency were not seen as
Match 3 (1):
Reference (000591 .. 000623, of 13533):
Subject (008904 .. 008937, of 28080):
able to turn a reptile into a mammal or to convert a fish into an amphibian Microevolution looks at adaptations that concern the survival of the fittest not the arrival of the fittest
able to turn a reptile into a mammal or to convert a fish into an amphibian Microevolution looks at adaptations that concern only the survival of the fittest not the arrival of the fittest
Match 4 (1):
Reference (000853 .. 000862, of 13533):
Subject (020356 .. 020366, of 28080):
of the origin of biological form and information during the
of the origin of biological information exposes a deficiency in the
Match 5 (1):
Reference (000999 .. 001010, of 13533):
Subject (000571 .. 000587, of 28080):
time at least nineteen and perhaps as many as thirty five phyla
time During this event at least nineteen and as many as thirty five of forty total phyla
Match 6 (1):
Reference (001112 .. 001140, of 13533):
Subject (001005 .. 001035, of 28080):
To say that the fauna of the Cambrian period appeared in a geologically sudden manner also implies the absence of clear transitional intermediate forms connecting Cambrian animals with simpler
To say that the fauna of the Cambrian period appeared in a geologically sudden manner also implies the absence of clear transitional intermediates connecting the complex Cambrian animals with those simpler
Match 7 (1):
Reference (001789 .. 001823, of 13533):
Subject (002957 .. 002991, of 28080):
information In classical Shannon information theory the amount of information in a system is also inversely related to the probability of the arrangement of constituents in a system or the characters along a communication channel
in biology In classical Shannon information theory the amount of information in a system is inversely related to the probability of the arrangement of constituents in a system or the characters along a communication channel
Match 8 (1):
Reference (001826 .. 001897, of 13533):
Subject (002993 .. 003061, of 28080):
The more improbable or complex the arrangement the more Shannon information or information carrying capacity a string or system possesses Since the 1960s mathematical biologists have realized that Shannon s theory could be applied to the analysis of DNA and proteins to measure the information carrying capacity of these macromolecules Since DNA contains the assembly instructions for building proteins the information processing system in the cell represents a kind of communication channel
The more improbable or complex the arrangement the more Shannon information or information carrying capacity a string or system possesses Since the 1960s mathematical biologists have realized that Shannon s theory could be applied to the analysis of DNA and proteins to measure their information carrying capacity Since DNA contains the assembly instructions for building proteins the information processing system in the cell represents a kind of communication channel
Match 9 (1):
Reference (001911 .. 001920, of 13533):
Subject (003086 .. 003097, of 28080):
bases Since each of the four bases has a roughly
a linear array Since each of the four bases has a roughly
Match 10 (1):
Reference (001911 .. 002032, of 13533):
Subject (003086 .. 003210, of 28080):
bases Since each of the four bases has a roughly equal chance of occurring at each site along the spine of the DNA molecule biologists can calculate the probability and thus the information carrying capacity of any particular sequence n bases long The ease with which information theory applies to molecular biology has created confusion about the type of information that DNA and proteins possess Sequences of nucleotide bases in DNA or amino acids in a protein are highly improbable and thus have large information carrying capacities But like meaningful sentences or lines of computer code genes and proteins are also specified with respect to function Just as the meaning of a sentence depends upon the specific arrangement of the letters in
a linear array Since each of the four bases has a roughly equiprobable chance of occurring at each site along the spine of the DNA molecule biologists can calculate the probability and thus the information carrying capacity of any particular sequence n bases long The ease with which information theory applies to molecular biology has created confusion about the type of information that DNA and proteins possess Sequences of nucleotide bases in DNA or amino acids in a protein are highly improbable and thus have a large information carrying capacity But like meaningful sentences or lines of computer code genes and proteins are also specified with respect to function Just as the meaning of a sentence depends upon the specific arrangement of the letters in
Match 11 (1):
Reference (001911 .. 002054, of 13533):
Subject (003086 .. 003235, of 28080):
bases Since each of the four bases has a roughly equal chance of occurring at each site along the spine of the DNA molecule biologists can calculate the probability and thus the information carrying capacity of any particular sequence n bases long The ease with which information theory applies to molecular biology has created confusion about the type of information that DNA and proteins possess Sequences of nucleotide bases in DNA or amino acids in a protein are highly improbable and thus have large information carrying capacities But like meaningful sentences or lines of computer code genes and proteins are also specified with respect to function Just as the meaning of a sentence depends upon the specific arrangement of the letters in a sentence so too does the function of a gene sequence depend upon the specific arrangement of the nucleotide bases in a
a linear array Since each of the four bases has a roughly equiprobable chance of occurring at each site along the spine of the DNA molecule biologists can calculate the probability and thus the information carrying capacity of any particular sequence n bases long The ease with which information theory applies to molecular biology has created confusion about the type of information that DNA and proteins possess Sequences of nucleotide bases in DNA or amino acids in a protein are highly improbable and thus have a large information carrying capacity But like meaningful sentences or lines of computer code genes and proteins are also specified with respect to function Just as the meaning of a sentence depends upon the specific arrangement of the letters in the sentence so too does the function of a gene sequence depend upon the specific arrangement of the nucleotide bases in the gene Thus as
Match 12 (1):
Reference (002057 .. 002080, of 13533):
Subject (003239 .. 003262, of 28080):
molecular biologists beginning with Crick equated information not only with complexity but also with specificity where specificity or specified has meant necessary to function
molecular biologists beginning with Francis Crick have equated information not only with complexity but also with specificity where specificity has meant necessary to function
Match 13 (1):
Reference (002162 .. 002178, of 13533):
Subject (003127 .. 003144, of 28080):
function The ease with which information theory applies to molecular biology has also created confusion about the
n bases long The ease with which information theory applies to molecular biology has created confusion about the
Match 14 (1):
Reference (002407 .. 002418, of 13533):
Subject (003732 .. 003752, of 28080):
Cambrian explosion represents a remarkable jump in the specified complexity or complex
Cambrian explosion represents a remarkable jump in the specified information or specified complexity of the biological world FIGURE 10 Biological Complexity
Match 15 (1):
Reference (002413 .. 002425, of 13533):
Subject (003281 .. 003291, of 28080):
in the specified complexity or complex specified information CSI of the biological world
in the specified complexity or specified information of the biological world
Match 16 (1):
Reference (002430 .. 002440, of 13533):
Subject (002733 .. 002747, of 28080):
years the biological realm included little more than bacteria and algae
s history the biological realm included little more than unicellular bacteria and blue green algae
the Cambrian explosion represents a steep climb up the biology complexity
Match 19 (1):
Reference (002591 .. 002604, of 13533):
Subject (003339 .. 003353, of 28080):
Functionally more complex animals require more cell types to perform their more diverse functions
Functionally more complex animal forms require more cell types to perform their more diverse functions
Match 20 (1):
Reference (002613 .. 002659, of 13533):
Subject (003457 .. 003504, of 28080):
proteins New proteins in turn require new genetic information Thus an increase in the number of cell types implies at a minimum a considerable increase in the amount of specified genetic information Molecular biologists have recently estimated that a minimally complex single celled organism would require between
proteins in turn require new genetic information encoded in DNA Thus an increase in the number of cell types implies at a minimum a considerable increase in the amount of specified genetic information Molecular biologists have recently estimated that a minimally complex single celled organism would require between
Match 21 (1):
Reference (002659 .. 002674, of 13533):
Subject (003520 .. 003535, of 28080):
between 318 and 562 kilobase pairs of DNA to produce the proteins necessary to maintain life
between 318 and 562 kilobase pairs of DNA to produce the proteins necessary to maintain life
Match 22 (1):
Reference (002677 .. 002698, of 13533):
Subject (003537 .. 003558, of 28080):
More complex single cells might require upward of a million base pairs Yet to build the proteins necessary to sustain a complex
More complex single cells might require upward of 1 million base pairs Yet to build the proteins necessary to sustain a complex
Match 23 (1):
Reference (002713 .. 002724, of 13533):
Subject (003571 .. 003581, of 28080):
genome size of a modern arthropod the fruitfly Drosophila melanogaster is approximately
genome size of the fly Drosophila melanogaster an arthropod is approximately
Match 24 (1):
Reference (002737 .. 002756, of 13533):
Subject (003608 .. 003627, of 28080):
Transitions from a single cell to colonies of cells to complex animals represent significant and in principle measurable increases in
transitions from a single cell to colonies of cells to complex animals represent significant and in principle measurable increases in
Match 25 (1):
Reference (002936 .. 002958, of 13533):
Subject (014998 .. 015022, of 28080):
Many scientists and mathematicians have questioned the ability of mutation and selection to generate information in the form of novel genes and proteins
a number of scientists and mathematicians have questioned the ability of mutation and selection to generate information in the form of novel genes and proteins
Match 26 (1):
Reference (002962 .. 002980, of 13533):
Subject (015026 .. 015044, of 28080):
derives from consideration of the extreme improbability and specificity of functional genes and proteins A typical gene contains over
derived from consideration of the extreme improbability and specificity of functional genes and proteins A typical gene contains over
Match 27 (1):
Reference (002987 .. 002997, of 13533):
Subject (015052 .. 015062, of 28080):
any specific arrangement of four nucleotide bases of length n there
any specific arrangement of four nucleotide bases of length n there
Match 28 (1):
Reference (002999 .. 003075, of 13533):
Subject (015064 .. 015143, of 28080):
a corresponding number of possible arrangements of bases 4n For any protein there are 20n possible arrangements of protein forming amino acids A gene 999 bases in length represents one of 4999 possible nucleotide sequences a protein of 333 amino acids is one of 20333 possibilities Since the 1960s some biologists have thought functional proteins to be rare among the set of possible amino acid sequences Some have used an analogy with human language to illustrate why
a corresponding number of 4n possible arrangements of bases For any protein there are 20n possible arrangements of protein forming amino acids A gene of 999 bases in length represents one of 4999 possible nucleotide sequences a protein of 333 amino acids one of 20333 possibilities Since the 1960s biologists have generally thought functional proteins to be rare among the set of possible amino acid sequences of corresponding length Some have used an analogy with human language to illustrate why
Match 29 (1):
Reference (003093 .. 003157, of 13533):
Subject (015154 .. 015218, of 28080):
sentences are extremely rare among the set of possible combinations of English letters especially as sequence length grows The ratio of meaningful 12 letter words to 12 letter sequences is 1 1014 the ratio of 100 letter sentences to possible 100 letter strings is 1 10100 Further Denton shows that most meaningful sentences are highly isolated from one another in the space of possible combinations
sentences are extremely rare among the set of possible combinations of English letters especially as sequence length grows The ratio of meaningful 12 letter words to 12 letter sequences is 1 1014 the ratio of 100 letter sentences to possible 100 letter strings is 1 10100 Further Denton shows that most meaningful sentences are highly isolated from one another in the space of possible combinations
Match 30 (1):
Reference (003159 .. 003224, of 13533):
Subject (015220 .. 015284, of 28080):
that random substitutions of letters will after a very few changes inevitably degrade meaning Apart from a few closely clustered sentences accessible by random substitution the overwhelming majority of meaningful sentences lie probabilistically speaking beyond the reach of random search Denton 1986 301 324 and others have argued that similar constraints apply to genes and proteins They have questioned whether an undirected search via mutation and
that random substitutions of letters will after a very few changes inevitably degrade meaning Apart from a few closely clustered sentences accessible by random substitution the overwhelming majority of meaningful sentences lie probabilistically speaking beyond the reach of random search Denton and others have argued that similar constraints apply to genes They have questioned therefore whether an undirected search via mutation selection would have a
Match 31 (1):
Reference (003159 .. 003246, of 13533):
Subject (015220 .. 015300, of 28080):
that random substitutions of letters will after a very few changes inevitably degrade meaning Apart from a few closely clustered sentences accessible by random substitution the overwhelming majority of meaningful sentences lie probabilistically speaking beyond the reach of random search Denton 1986 301 324 and others have argued that similar constraints apply to genes and proteins They have questioned whether an undirected search via mutation and selection would have a reasonable chance of locating new islands of function representing fundamentally new genes or proteins within the time available
that random substitutions of letters will after a very few changes inevitably degrade meaning Apart from a few closely clustered sentences accessible by random substitution the overwhelming majority of meaningful sentences lie probabilistically speaking beyond the reach of random search Denton and others have argued that similar constraints apply to genes They have questioned therefore whether an undirected search via mutation selection would have a reasonable chance of locating new islands of function representing fundamentally new genes or proteins within available
Match 32 (1):
Reference (003253 .. 003274, of 13533):
Subject (015303 .. 015324, of 28080):
Some have also argued that alterations in sequencing would likely result in loss of protein function before fundamentally new function could arise
Some have also argued that alterations in sequencing would likely result in loss of protein function before fundamentally new function could arise
Match 33 (1):
Reference (003285 .. 003349, of 13533):
Subject (015330 .. 015392, of 28080):
genes and proteins are sensitive to functional loss as a result of sequence change nor the extent to which functional proteins are isolated within sequence space has been fully known Recently experiments in molecular biology have shed light on these questions A variety of mutagenesis techniques have shown that proteins and thus the genes that produce them are indeed highly specified relative to biological function
genes and proteins to functional loss as the result of sequence change nor the extent to which functional proteins are isolated within sequence space has been fully known Recently experiments in molecular biology have shed light on these questions A variety of mutagenesis techniques have shown that proteins and thus the genes that produce them are indeed highly specified relative to biological function
Match 34 (1):
Reference (003287 .. 003297, of 13533):
Subject (015532 .. 015546, of 28080):
proteins are sensitive to functional loss as a result of sequence
proteins are highly sensitive to functional loss as a result of alterations in the sequencing
Match 35 (1):
Reference (003361 .. 003381, of 13533):
Subject (015394 .. 015414, of 28080):
Mutagenesis research tests the sensitivity of proteins and by implication DNA to functional loss as a result of alterations in sequencing
Mutagenesis research tests the sensitivity of proteins and by implication DNA to functional loss as a result of alterations in sequencing
Match 36 (1):
Reference (003452 .. 003461, of 13533):
Subject (015496 .. 015506, of 28080):
multiple as opposed to single position amino acid substitutions inevitably
multiple as opposed to single amino acid substitutions generally result in
Match 37 (1):
Reference (003462 .. 003529, of 13533):
Subject (015505 .. 015575, of 28080):
result in loss of protein function even when these changes occur at sites that allow variation when altered in isolation Cumulatively these constraints imply that proteins are highly sensitive to functional loss as a result of alterations in sequencing and that functional proteins represent highly isolated and improbable arrangements of amino acids arrangements that are far more improbable in fact than would be likely to arise by chance
result in rapid loss of protein function even when these changes occur at sites that allow variation when altered in isolation 93 Cumulatively these constraints imply that proteins are highly sensitive to functional loss as a result of alterations in the sequencing and that functional proteins represent highly isolated and improbable arrangements of amino acids arrangements that are far more improbable in fact than would be likely to arise by chance
Match 38 (1):
Reference (003566 .. 003578, of 13533):
Subject (015583 .. 015595, of 28080):
Of course neo Darwinists do not envision a completely random search through the
Of course neo Darwinists do not envision a completely random search through the
Match 39 (1):
Reference (003591 .. 003777, of 13533):
Subject (015603 .. 015790, of 28080):
natural selection acting to preserve small advantageous variations in genetic sequences and their corresponding protein products Dawkins 1996 for example likens an organism to a high mountain peak He compares climbing the sheer precipice up the front side of the mountain to building a new organism by chance He acknowledges that his approach up Mount Improbable will not succeed Nevertheless he suggests that there is a gradual slope up the backside of the mountain that could be climbed in small incremental steps In his analogy the backside climb up Mount Improbable corresponds to the process of natural selection acting on random changes in the genetic text What chance alone cannot accomplish blindly or in one leap selection acting on mutations can accomplish through the cumulative effect of many slight successive steps Yet the extreme specificity and complexity of proteins presents a difficulty not only for the chance origin of specified biological information i e for random mutations acting alone but also for selection and mutation acting in concert Indeed mutagenesis experiments cast doubt on each of the two scenarios by which neo Darwinists envisioned new information arising
natural selection acting to preserve small advantageous variations in genetic sequences and their corresponding protein products Richard Dawkins for example likens an organism to a high mountain peak 95 He compares climbing the sheer precipice up the front side of the mountain to building a new organism by chance He acknowledges that this approach up Mount Improbable will not succeed Nevertheless he suggests that there is a gradual slope up the backside of the mountain that could be climbed in small incremental steps In his analogy the backside up Mount Improbable corresponds to the process of natural selection acting on random changes in the genetic text What chance alone cannot accomplish blindly or in one leap selection acting on mutations can accomplish through the cumulative effect of many slight successive steps Yet the extreme specificity and complexity of proteins present a diffi culty not only for the chance origin of specified biological information that is for random mutations acting alone but also for selection and mutation acting in concert Indeed mutagenesis experiments cast doubt on each of the two scenarios by which neo Darwinists envision new information arising
Match 40 (1):
Reference (003790 .. 003862, of 13533):
Subject (015799 .. 015872, of 28080):
Darwinism new functional genes either arise from non coding sections in the genome or from preexisting genes Both scenarios are problematic In the first scenario neo Darwinists envision new genetic information arising from those sections of the genetic text that can presumably vary freely without consequence to the organism According to this scenario non coding sections of the genome or duplicated sections of coding regions can experience a protracted period of neutral evolution
Darwinists either new functional genes arise from noncoding sections in the genome or functional genes arise from preexisting genes Both scenarios are problematic In the first scenario neo Darwinists envision new genetic information arising from those sections of the genetic text that can presumably vary freely without consequence to the organism According to this scenario noncoding sections of the genome or duplicated sections of coding regions can experience a protracted period of neutral evolution
Match 41 (1):
Reference (003794 .. 003956, of 13533):
Subject (015800 .. 015968, of 28080):
either arise from non coding sections in the genome or from preexisting genes Both scenarios are problematic In the first scenario neo Darwinists envision new genetic information arising from those sections of the genetic text that can presumably vary freely without consequence to the organism According to this scenario non coding sections of the genome or duplicated sections of coding regions can experience a protracted period of neutral evolution Kimura 1983 during which alterations in nucleotide sequences have no discernible effect on the function of the organism Eventually however a new gene sequence will arise that can code for a novel protein At that point natural selection can favor the new gene and its functional protein product thus securing the preservation and heritability of both This scenario has the advantage of allowing the genome to vary through many generations as mutations search the space of possible base sequences The scenario has an overriding problem however the size of the combinatorial space i e
either new functional genes arise from noncoding sections in the genome or functional genes arise from preexisting genes Both scenarios are problematic In the first scenario neo Darwinists envision new genetic information arising from those sections of the genetic text that can presumably vary freely without consequence to the organism According to this scenario noncoding sections of the genome or duplicated sections of coding regions can experience a protracted period of neutral evolution in which alterations in nucleotide sequences have no discernible effect on the function of the organism Eventually however a new gene sequence will arise that can code for a novel protein At that point natural selection can favor the new gene and its functional protein product thus securing the preservation and heritability of both This scenario has the advantage of allowing the genome to vary through many generations as mutations search the space of possible base sequences The scenario has an overriding problem however the size of the combinatorial space and the extreme rarity of the
Match 42 (1):
Reference (003964 .. 004022, of 13533):
Subject (015963 .. 016017, of 28080):
and the extreme rarity and isolation of the functional sequences within that space of possibilities Since natural selection can do nothing to help generate new functional sequences but rather can only preserve such sequences once they have arisen chance alone random variation must do the work of information generation that is of finding the exceedingly rare functional sequences within
and the extreme rarity of the functional sequences within that space of possibilities Since natural selection can do nothing to help generate new functional sequences but rather can only preserve such sequences once they have arisen chance alone random variation must do the work of information generation that is of finding rare functional sequences within
Match 43 (1):
Reference (004025 .. 004043, of 13533):
Subject (016020 .. 016038, of 28080):
of combinatorial possibilities Yet the probability of randomly assembling or finding in the previous sense a functional sequence is
of combinatorial possibilities Yet the probability of randomly assembling or finding in the previous sense a functional sequence is
Match 44 (1):
Reference (004054 .. 004077, of 13533):
Subject (016051 .. 016078, of 28080):
suggest that the probability of attaining at random the correct sequencing for a short protein 100 amino acids long is about 1 in 1065
s mutagenesis experiments imply that the probability of attaining at random the correct sequencing for a short protein 100 amino acids long is about 1 chance in 1065
Match 45 (1):
Reference (004207 .. 004217, of 13533):
Subject (015119 .. 015130, of 28080):
to b the whole set of possible amino acids sequences of
to be rare among the set of possible amino acid sequences of
Match 46 (1):
Reference (004239 .. 004248, of 13533):
Subject (015115 .. 015131, of 28080):
a functional protein among the possible amino acid sequences corresponding
generally thought functional proteins to be rare among the set of possible amino acid sequences of corresponding
Match 47 (1):
Reference (004259 .. 004318, of 13533):
Subject (016099 .. 016158, of 28080):
Other considerations imply additional improbabilities First new Cambrian animals would require proteins much longer than 100 residues to perform many necessary specialized functions Ohno 1996 has noted that Cambrian animals would have required complex proteins such as lysyl oxidase in order to support their stout body structures Lysyl oxidase molecules in extant organisms comprise over 400 amino acids These molecules
Other considerations imply additional improbabilities First new Cambrian animals would require proteins much longer than 100 residues to perform necessary specialized functions Susumu Ohno has noted that Cambrian animals would have required complex proteins such as lysyl oxidase in order to support their stout body structures 98 Lysyl oxidase molecules in extant organisms comprise over 400 amino acids These molecules
Match 48 (1):
Reference (004327 .. 004352, of 13533):
Subject (016165 .. 016193, of 28080):
specified Reasonable extrapolation from mutagenesis experiments done on shorter protein molecules suggests that the probability of producing functionally sequenced proteins of this length at random is
specified arrangements of matter Reasonable extrapolation from mutagenesis experiments done on shorter protein molecules suggests that the probability of producing functionally sequenced proteins of this length at random is
Match 49 (1):
Reference (004450 .. 004479, of 13533):
Subject (016263 .. 016292, of 28080):
Third DNA mutation rates are far too low to generate the novel genes and proteins necessary to building the Cambrian animals given the most probable duration of the explosion as
Third DNA mutation rates are far too slow to generate the novel genes and proteins necessary to building the Cambrian animals given the duration of the explosion As Ohno has
Match 50 (1):
Reference (004544 .. 004561, of 13533):
Subject (016388 .. 016405, of 28080):
The selection mutation mechanism faces another probabilistic obstacle The animals that arise in the Cambrian exhibit structures that
The mutation selection mechanism faces another probabilistic obstacle The animals that arise in the Cambrian exhibit structures that
Match 51 (1):
Reference (004565 .. 004721, of 13533):
Subject (016407 .. 016559, of 28080):
many new types of cells each of which would have required many novel proteins to perform their specialized functions Further new cell types require systems of proteins that must as a condition of functioning act in close coordination with one another The unit of selection in such systems ascends to the system as a whole Natural selection selects for functional advantage But new cell types require whole systems of proteins to perform their distinctive functions In such cases natural selection cannot contribute to the process of information generation until after the information necessary to build the requisite system of proteins has arisen Thus random variations must again do the work of information generation and now not simply for one protein but for many proteins arising at nearly the same time Yet the odds of this occurring by chance alone are of course far smaller than the odds of the chance origin of a single gene or protein
many new types of cells each of which would require many novel proteins to perform their specialized functions Further new cell types require systems of proteins that must as a condition of function act in close coordination with one another The unit of selection in such systems ascends to the system as a whole Natural selection selects for functional advantage But new cell types require whole systems of proteins to perform their distinctive functions In such cases natural selection cannot contribute to the process of information generation until after the information necessary to build the requisite system of proteins has arisen Thus random variations must again do the work of information generation and now not simply for one protein but for many proteins arising at nearly the same time Yet the odds of this occurring by chance are far smaller than the odds of the chance origin of a single gene or protein
Match 52 (1):
Reference (004729 .. 004738, of 13533):
Subject (014642 .. 014649, of 28080):
the chance origin of the genetic information necessary to build
the origin of the information necessary to build
Match 53 (1):
Reference (004790 .. 004866, of 13533):
Subject (016583 .. 016661, of 28080):
The neutral theory of evolution which by its own logic prevents natural selection from playing a role in generating genetic information until after the fact relies on entirely too much luck The sensitivity of proteins to functional loss the need for long proteins to build new cell types and animals the need for whole new systems of proteins to service new cell types the probable brevity of the Cambrian explosion relative to mutation rates all suggest the
The neutral theory of evolution which by its own logic prevents natural selection from playing a role in generating genetic information until after the fact relies on entirely too much luck The sensitivity of proteins to functional loss the need for long proteins to build new cell types and animals the need for whole new systems of proteins to service new cell types the brevity of the Cambrian explosion relative to mutation rates all these factors suggest that the
Match 54 (1):
Reference (004870 .. 004881, of 13533):
Subject (014544 .. 014554, of 28080):
implausibility of any scenario for the origination of Cambrian genetic information that
s previous discussion of the origin of genetic information in a
Match 55 (1):
Reference (004887 .. 004949, of 13533):
Subject (016684 .. 016747, of 28080):
unassisted by natural selection Yet the neutral theory requires novel genes and proteins to arise essentially by random mutation alone Adaptive advantage accrues after the generation of new functional genes and proteins Thus natural selection cannot play a role until new information bearing molecules have independently arisen Thus neutral theorists envisioned the need to scale the steep face of a Dawkins style precipice
unassisted by natural selection Yet the neutral theory requires novel genes and proteins to arise essentially by random mutation alone Adaptive advantage accrues after the generation of new functional genes and proteins Thus natural selection cannot play a role until new information bearing molecules have independently arisen Thus the neutral theory envisions the need to scale the steep face of a Dawkins style precipice
Match 56 (1):
Reference (004951 .. 004984, of 13533):
Subject (016749 .. 016783, of 28080):
which there is no gradually sloping backside a situation that by Dawkins own logic is probabilistically untenable In the second scenario neo Darwinists envisioned novel genes and proteins arising by numerous successive mutations in
which there is no gradually sloping backside a situation that by Dawkins s own logic is probabilistically untenable In the second scenario neo Darwinists envision novel genes and proteins arising by numerous successive mutations in
Match 57 (1):
Reference (004986 .. 005019, of 13533):
Subject (016785 .. 016819, of 28080):
preexisting genetic text that codes for proteins To adapt Dawkins s metaphor this scenario envisions gradually climbing down one functional peak and then ascending another Yet mutagenesis experiments again suggest a difficulty Recent experiments
preexisting genetic text that codes for proteins To adapt Dawkins s metaphor slightly this scenario envisions gradually climbing down one functional peak and then ascending another Yet mutagenesis experiments again suggest a difficulty Recent experiments
Match 58 (1):
Reference (005020 .. 005048, of 13533):
Subject (016827 .. 016853, of 28080):
show that even when exploring a region of sequence space populated by proteins of a single fold and function most multiple position changes quickly lead to loss of function
show that even when exploring a region of sequence space populated by proteins of a single function most multiple position changes quickly lead to loss of function
Match 59 (1):
Reference (005051 .. 005065, of 13533):
Subject (016855 .. 016867, of 28080):
Yet to turn one protein into another with a completely novel structure and function requires
Yet to turn one protein into another with a completely novel function requires
Match 60 (1):
Reference (005132 .. 005161, of 13533):
Subject (016878 .. 016908, of 28080):
Axe s results imply that in all probability random searches for novel proteins through sequence space will result in functional loss long before any novel functional protein will emerge Blanco
Axe s results imply that in all probability random searches for novel proteins through sequence space will result in functional loss long before any novel functional protein will emerge Francisco Blanco
Match 61 (1):
Reference (005247 .. 005279, of 13533):
Subject (017014 .. 017046, of 28080):
Thus although this second neo Darwinian scenario has the advantage of starting with functional genes and proteins it also has a lethal disadvantage any process of random mutation or rearrangement in the genome
Thus although this second neo Darwinian scenario has the advantage of starting with functional genes and proteins it also has a lethal disadvantage any process of random mutation or rearrangement in the genome
Match 62 (1):
Reference (005300 .. 005348, of 13533):
Subject (017068 .. 017118, of 28080):
sequences confer no survival advantage on their host organisms Natural selection favors only functional advantage It cannot select or favor nucleotide sequences or polypeptide chains that do not yet perform biological functions and still less will it favor sequences that efface or destroy preexisting function Evolving genes and proteins
sequences would thus confer no survival advantage on their host organisms Yet natural selection favors only functional advantage It cannot select or favor nucleotide sequences or polypeptide chains that do not yet perform biological functions still less will it favor sequences that efface or destroy preexisting function Evolving genes and proteins
Match 63 (1):
Reference (005350 .. 005371, of 13533):
Subject (017120 .. 017141, of 28080):
range through a series of nonfunctional intermediate sequences that natural selection will not favor or preserve but will in all probability eliminate
range through a series of nonfunctional intermediate sequences that natural selection will not favor or preserve but will in all probability eliminate
Match 64 (1):
Reference (005378 .. 005407, of 13533):
Subject (017143 .. 017173, of 28080):
When this happens selection driven evolution will cease At this point neutral evolution of the genome unhinged from selective pressure may ensue but as we have seen such a process
When this happens selection driven evolution will cease At this point neutral evolution of the genome unhinged from selective pressure may ensue but as we have already seen such a process
Match 65 (1):
Reference (005413 .. 005543, of 13533):
Subject (017183 .. 017317, of 28080):
even granting cosmic time Thus whether one envisions the evolutionary process beginning with a noncoding region of the genome or a preexisting functional gene the functional specificity and complexity of proteins impose very stringent limitations on the efficacy of mutation and selection In the first case function must arise first before natural selection can act to favor a novel variation In the second case function must be continuously maintained in order to prevent deleterious or lethal consequences to the organism and to allow further evolution Yet the complexity and functional specificity of proteins implies that both these conditions will be extremely difficult to meet Therefore the neo Darwinian mechanism appears to be inadequate to generate the new information present in the novel genes and proteins that arise with the Cambrian animals
even granting a cosmic time scale Thus whether one envisions the evolutionary process beginning with a noncoding region of the genome or a preexisting functional gene the functional specificity and complexity of proteins impose very stringent limitations on the efficacy of mutation and selection In the first case function must arise first before natural selection can act to favor a novel variation In the second case function must be continuously maintained to prevent deleterious or lethal consequences to the organism and to allow for the possibility of further evolution Yet the complexity and functional speci ficity of proteins imply that both these conditions will be extremely diffi cult to meet Therefore the neo Darwinian mechanism appears inadequate to generate the new information present in the novel genes and proteins that arise with the Cambrian animals
Match 66 (1):
Reference (005560 .. 005595, of 13533):
Subject (017335 .. 017370, of 28080):
explain the origin of the Cambrian animals one must account not only for new proteins and cell types but also for the origin of new body plans Within the past decade developmental biology has dramatically advanced
explain the origin of the Cambrian animals one must account not only for new proteins and cell types but also for the origin of new body plans Within the past decade developmental biology has dramatically advanced
Match 67 (1):
Reference (005597 .. 005615, of 13533):
Subject (017443 .. 017461, of 28080):
understanding of how body plans are built during ontogeny In the process it has also uncovered a profound difficulty
understanding of how body plans are built during ontogeny In the process it has also uncovered a profound difficulty
Match 68 (1):
Reference (005621 .. 005655, of 13533):
Subject (017472 .. 017510, of 28080):
change in organisms requires attention to timing Mutations in genes that are expressed late in the development of an organism will not affect the body plan Mutations expressed early in development however could conceivably produce
changes in the form of organisms requires attention to timing Mutations in genetic material that are expressed late in the development of an organism will not affect the body plan Mutations expressed early in development however could conceivably produce
Match 69 (1):
Reference (005662 .. 005681, of 13533):
Subject (017520 .. 017539, of 28080):
Thus events expressed early in the development of organisms have the only realistic chance of producing large scale macroevolutionary change
Thus events expressed early in the development of organisms have the only realistic chance of producing large scale macroevolutionary change
Match 70 (1):
Reference (005702 .. 005718, of 13533):
Subject (017555 .. 017571, of 28080):
Yet recent studies in developmental biology make clear that mutations expressed early in development typically have deleterious
Yet recent studies in developmental biology make clear that mutations expressed early in development typically have deleterious
Match 71 (1):
Reference (005723 .. 005754, of 13533):
Subject (017588 .. 017620, of 28080):
For example when early acting body plan molecules or morphogens such as bicoid which helps to set up the anterior posterior head to tail axis in Drosophila are perturbed development shuts down
For example when early acting body plan molecules or morphogens such as bicoid which helps set up the anterior posterior head to tail axis in the fly Drosophila are perturbed development shuts down
Match 72 (1):
Reference (005766 .. 005837, of 13533):
Subject (017622 .. 017693, of 28080):
The resulting embryos die Moreover there is a good reason for this If an engineer modifies the length of the piston rods in an internal combustion engine without modifying the crankshaft accordingly the engine won t start Similarly processes of development are tightly integrated spatially and temporally such that changes early in development will require a host of other coordinated changes in separate but functionally interrelated developmental processes downstream For this reason
The resulting embryos die Moreover there is a good reason for this If an engineer modifies the length of the piston rods in an internal combustion engine without modifying the crankshaft accordingly the engine won t start Similarly processes of development are so tightly integrated spatially and temporally that changes early in development will require a host of other coordinated changes in separate but functionally interrelated developmental processes downstream For this reason
Match 73 (1):
Reference (005874 .. 005887, of 13533):
Subject (017856 .. 017871, of 28080):
This problem has led to what McDonald 1983 has called a great Darwinian paradox
This problem has led to what geneticist John F McDonald has called a great Darwinian paradox
Match 74 (1):
Reference (005914 .. 005924, of 13533):
Subject (017895 .. 017905, of 28080):
major changes the very stuff of macroevolution apparently do not vary
major changes the very stuff of macroevolution apparently do not vary
Match 75 (1):
Reference (005934 .. 005948, of 13533):
Subject (017990 .. 018004, of 28080):
doesn t need namely viable genetic mutations in DNA expressed late in development do occur
doesn t need namely viable genetic mutations in DNA expressed late in development do occur
that the kind of variations required by neo Darwinism favorable mutations
Match 77 (1):
Reference (006008 .. 006034, of 13533):
Subject (018049 .. 018078, of 28080):
occur Developmental biology has raised another formidable problem for the mutation selection mechanism Embryological evidence has long shown that DNA does not wholly determine morphological form Goodwin
occur Developmental biology has raised another formidable problem for the mutation selection mechanism Embryological evidence has long shown that DNA does not wholly determine morphological form suggesting that mutations in
Match 78 (1):
Reference (006043 .. 006062, of 13533):
Subject (018075 .. 018095, of 28080):
suggesting that mutations in DNA alone cannot account for the morphological changes required to build a new body plan DNA
suggesting that mutations in DNA alone cannot account for the morphological changes required to build a new body plan 112 DNA
Match 79 (1):
Reference (006043 .. 006084, of 13533):
Subject (018075 .. 018114, of 28080):
suggesting that mutations in DNA alone cannot account for the morphological changes required to build a new body plan DNA helps direct protein synthesis 7 It also helps to regulate the timing and expression of the synthesis of various proteins within cells
suggesting that mutations in DNA alone cannot account for the morphological changes required to build a new body plan 112 DNA directs protein synthesis It also helps regulate the timing and expression of the synthesis of various proteins within cells
Match 80 (1):
Reference (006086 .. 006104, of 13533):
Subject (018116 .. 018134, of 28080):
DNA alone does not determine how individual proteins assemble themselves into larger systems of proteins still less does it
DNA alone does not determine how individual proteins assemble themselves into larger systems of proteins still less does it
Instead other factors such as the three dimensional structure and organization of the cell membrane and cytoskeleton
Instead other factors such as the structure and organization of the cell membrane and cytoskeleton
Match 83 (1):
Reference (006149 .. 006161, of 13533):
Subject (018165 .. 018181, of 28080):
play important roles in determining body plan formation during embryogenesis For example the
play important roles in determining developmental pathways that determine body plan formation during embryogenesis For example the
Match 84 (1):
Reference (006163 .. 006202, of 13533):
Subject (018183 .. 018224, of 28080):
and location of the cytoskeleton influence the patterning of embryos Arrays of microtubules help to distribute the essential proteins used during development to their correct locations in the cell Of course microtubules themselves are made of many protein subunits Nevertheless
and location of microtubules in the cytoskeleton influence the patterning of embryos Arrays of microtubules help distribute the essential proteins used during development to their correct location in the cell 114 Of course microtubules themselves are made of many protein subunits Nevertheless
Match 85 (1):
Reference (006216 .. 006226, of 13533):
Subject (018223 .. 018237, of 28080):
subunits in the cell s microtubules are identical to one another
subunits Nevertheless the protein subunits in the cell s microtubules are identical to one another
Match 86 (1):
Reference (006232 .. 006254, of 13533):
Subject (018240 .. 018264, of 28080):
nor the genes that produce them account for the different shape of microtubule arrays that distinguish different kinds of embryos and developmental pathways
nor the genes that produce them account for the different shapes and locations of microtubule arrays that distinguish different kinds of embryos and developmental pathways
Match 87 (1):
Reference (006319 .. 006386, of 13533):
Subject (018301 .. 018368, of 28080):
At a building site builders will make use of many materials lumber wires nails drywall piping and windows Yet building materials do not determine the floor plan of the house or the arrangement of houses in a neighborhood Similarly electronic circuits are composed of many components such as resistors capacitors and transistors But such lower level components do not determine their own arrangement in an integrated circuit Biological
At a building site builders will make use of many materials lumber wires nails drywall piping and windows Yet building materials do not determine the floor plan of the house or the arrangement of houses in a neighborhood Similarly electronic circuits are composed of many components such as resistors capacitors and transistors But such lower level components do not determine their own arrangement in an integrated circuit Biological
Match 88 (1):
Reference (006388 .. 006475, of 13533):
Subject (018370 .. 018455, of 28080):
also depend on hierarchical arrangements of parts Genes and proteins are made from simple building blocks nucleotide bases and amino acids arranged in specific ways Cell types are made of among other things systems of specialized proteins Organs are made of specialized arrangements of cell types and tissues And body plans comprise specific arrangements of specialized organs Yet clearly the properties of individual proteins or indeed the lower level parts in the hierarchy generally do not fully determine the organization of the higher level structures and organizational patterns
also depend on hierarchical arrangements of parts Genes and proteins are made from simple building blocks nucleotide bases and amino acids arranged in specific ways Cell types are made of among other things systems of specialized proteins Organs are made of specialized arrangements of cell types and tissues And body plans comprise specific arrangements of organs Yet clearly the properties of individual proteins or indeed the lower level parts in the hierarchy generally do not determine the organization of the higher level structures and organizational patterns
Match 89 (1):
Reference (006479 .. 006523, of 13533):
Subject (018457 .. 018501, of 28080):
It follows that the genetic information that codes for proteins does not determine these higher level structures either These considerations pose another challenge to the sufficiency of the neo Darwinian mechanism Neo Darwinism seeks to explain the origin of new information form and structure as
It follows therefore that the genetic information that codes for proteins does not determine these higherlevel structures either These considerations pose another challenge to the sufficiency of the neo Darwinian mechanism Neo Darwinism seeks to explain the origin of new information form and structure as
Match 90 (1):
Reference (006479 .. 006573, of 13533):
Subject (018457 .. 018549, of 28080):
It follows that the genetic information that codes for proteins does not determine these higher level structures either These considerations pose another challenge to the sufficiency of the neo Darwinian mechanism Neo Darwinism seeks to explain the origin of new information form and structure as a result of selection acting on randomly arising variation at a very low level within the biological hierarchy namely within the genetic text Yet major morphological innovations depend on a specificity of arrangement at a much higher level of the organizational hierarchy a level that DNA alone does not determine
It follows therefore that the genetic information that codes for proteins does not determine these higherlevel structures either These considerations pose another challenge to the sufficiency of the neo Darwinian mechanism Neo Darwinism seeks to explain the origin of new information form and structure as the result of selection acting on randomly arising variation at a very low level within the biological hierarchy namely within the genetic text Yet major morphological innovations depend on a specificity of arrangement at a much higher level of the organizational hierarchy that DNA alone does not determine
Match 91 (1):
Reference (006576 .. 006632, of 13533):
Subject (018551 .. 018607, of 28080):
DNA is not wholly responsible for body plan morphogenesis then DNA sequences can mutate indefinitely without regard to realistic probabilistic limits and still not produce a new body plan Thus the mechanism of natural selection acting on random mutations in DNA cannot in principle generate novel body plans including those that first arose in the Cambrian explosion
DNA is not wholly responsible for body plan morphogenesis then DNA sequences can mutate indefinitely without regard to realistic probabilistic limits and still not produce a new body plan Thus the mechanism of natural selection acting on random mutations in DNA cannot in principle generate novel body plans including those that first arose in the Cambrian explosion
Match 92 (1):
Reference (007139 .. 007157, of 13533):
Subject (018617 .. 018636, of 28080):
Of course neo Darwinism is not the only evolutionary theory for explaining the origin of novel biological form Kauffman
Of course neo Darwinism is not the only evolutionary model for explaining the origin of novel biological form in an
Match 93 (1):
Reference (007175 .. 007317, of 13533):
Subject (018650 .. 018787, of 28080):
to account for the emergence of new form and presumably the information necessary to generate it Whereas neo Darwinism attempts to explain new form as the consequence of selection acting on random mutation Kauffman suggests that selection acts not mainly on random variations but on emergent patterns of order that self organize via the laws of nature Kauffman 1995 47 92 illustrates how this might work with various model systems in a computer environment In one he conceives a system of buttons connected by strings Buttons represent novel genes or gene products strings represent the law like forces of interaction that obtain between gene products i e proteins Kauffman suggests that when the complexity of the system as represented by the number of buttons and strings reaches a critical threshold new modes of organization can arise in the system for free that is
to account for the emergence of form and presumably the information necessary to generate it Whereas neo Darwinism attempts to explain new form as the consequence of selection acting on random mutation Kauffman suggests that selection acts not mainly on random variations but on emergent patterns of order that self organize via the laws of nature Kauffman illustrates how this might work with various model systems in a computer environment In one he conceives a system of buttons connected by strings Buttons represent novel genes or gene products strings the lawlike forces of interaction that obtain between gene products that is proteins Kauffman suggests that when the complexity of the system as represented by the number of connected buttons and strings reaches a critical threshold new modes of organization can arise in the system for free that is
Match 94 (1):
Reference (007330 .. 007352, of 13533):
Subject (018905 .. 018927, of 28080):
Another model that Kauffman develops is a system of interconnected lights Each light can flash in a variety of states on off twinkling
Another model that Kauffman develops is a system of interconnected lights Each light can flash in a variety of states on off twinkling
Match 95 (1):
Reference (007354 .. 007429, of 13533):
Subject (018931 .. 019010, of 28080):
Since there is more than one possible state for each light and many lights there are a vast number of possible states that the system can adopt Further in his system rules determine how past states will influence future states Kauffman asserts that as a result of these rules the system will if properly tuned eventually produce a kind of order in which a few basic patterns of light activity recur with greater than random frequency
Since there is more than one possible state for each light and many lights there are a vast number of possible states that the system as a whole can adopt Further in his system rules determine how past states will in fluence future states Kauffman asserts that as a result of these rules the system will soon if properly tuned produce a kind of order in which a few basic patterns of light activity recur with greater than random frequency
Match 96 (1):
Reference (007431 .. 007454, of 13533):
Subject (019014 .. 019037, of 28080):
these actual patterns of light activity represent a small portion of the total number of possible states in which the system can reside Kauffman
these actual patterns of light activity represent a small portion of the total number of possible states in which the system can reside Kauffman
Match 97 (1):
Reference (007458 .. 007534, of 13533):
Subject (019039 .. 019114, of 28080):
that self organizational laws might similarly result in highly improbable biological outcomes perhaps even sequences of bases or amino acids within a much larger sequence space of possibilities Do these simulations of self organizational processes accurately model the origin of novel genetic information It is hard to think so First in both examples Kauffman presupposes but does not explain significant sources of preexisting information In his buttons and strings system the buttons represent proteins themselves packets of
that self organizational laws might similarly find highly improbable biological outcomes perhaps even sequences of bases or amino acids within a much larger sequence space of possibilities Do these simulations of self organizational processes accurately model the origin of novel genetic information It s hard to think so First in both examples Kauffman presupposes but does not explain significant sources of preexisting information In his buttons and strings system the buttons represent proteins themselves packets of
Match 98 (1):
Reference (007536 .. 007567, of 13533):
Subject (019116 .. 019149, of 28080):
and the result of preexisting genetic information Where does this information come from Kauffman 1995 doesn t say but the origin of such information is an essential part of what needs to
and the result of preexisting genetic information Where does this information come from Kauffman doesn t say but the origin of such information is an essential part of what needs explanation in the history
Match 99 (1):
Reference (007570 .. 007587, of 13533):
Subject (019147 .. 019163, of 28080):
in the history of life Similarly in his light system the order that allegedly arises for for free
in the history of life Similarly in his light system the order that allegedly arises for free
Match 100 (1):
Reference (007588 .. 007616, of 13533):
Subject (019174 .. 019201, of 28080):
actually arises only if the programmer of the model system tunes it in such a way as to keep it from either a generating an excessively rigid order or
actually arises only if the programmer of the model system tunes it in such a way as to keep it from either generating an excessively rigid order or
Match 101 (1):
Reference (007628 .. 007687, of 13533):
Subject (019214 .. 019272, of 28080):
involves an intelligent programmer selecting certain parameters and excluding others that is inputting information Second Kauffman s model systems are not constrained by functional considerations and thus are not analogous to biological systems A system of interconnected lights governed by pre programmed rules may well settle into a small number of patterns within a much larger space of possibilities But
involves an intelligent programmer selecting certain parameters and excluding others that is inputting information Second Kauffman s model systems are not constrained by functional considerations and thus are not analogous to biological systems A system of interconnected lights governed by preprogrammed rules may well settle into a small number of patterns within a much larger space of possibilities But
Match 102 (1):
Reference (007689 .. 007749, of 13533):
Subject (019274 .. 019333, of 28080):
these patterns have no function and need not meet any functional requirements they have no specificity analogous to that present in actual organisms Instead examination of Kauffman s 1995 model systems shows that they do not produce sequences or systems characterized by specified complexity but instead by large amounts of symmetrical order or internal redundancy interspersed with aperiodicity or mere complexity
these patterns have no function and need not meet any functional requirements they have no specificity analogous to that present in actual organisms Instead examination of Kauffman s model systems shows that they do not produce sequences or systems characterized by specified complexity but instead by large amounts of symmetrical order or internal redundancy interspersed with aperiodicity or mere complexity
Match 103 (1):
Reference (007754 .. 007785, of 13533):
Subject (019335 .. 019366, of 28080):
Getting a law governed system to generate repetitive patterns of flashing lights even with a certain amount of variation is clearly interesting but not biologically relevant On the other hand a system
Getting a law governed system to generate repetitive patterns of flashing lights even with a certain amount of variation is clearly interesting but not biologically relevant On the other hand a system
Match 104 (1):
Reference (007795 .. 007807, of 13533):
Subject (019375 .. 019390, of 28080):
would model a biologically relevant self organizational process at least if such a
would model a biologically relevant self organizational process at least if the system produced such messages
Match 105 (1):
Reference (007826 .. 007845, of 13533):
Subject (019401 .. 019420, of 28080):
In any case Kauffman s systems do not produce specified complexity and thus do not offer promising models for explaining
In any case Kauffman s systems do not produce specified complexity and thus do not offer promising models for explaining
Match 106 (1):
Reference (007856 .. 007934, of 13533):
Subject (019450 .. 019527, of 28080):
Even so Kauffman suggests that his self organizational models can specifically elucidate aspects of the Cambrian explosion According to Kauffman 1995 199 201 new Cambrian animals emerged as the result of long jump mutations that established new body plans in a discrete rather than gradual fashion He also recognizes that mutations affecting early development are almost inevitably harmful Thus he concludes that body plans once established will not change and that any subsequent evolution must occur within an established
Even so Kauffman suggests that his self organizational models can specifi cally elucidate aspects of the Cambrian explosion According to Kauffman new Cambrian animals emerged as the result of long jump mutations that established new body plans in a discrete rather than gradual fashion 120 He also recognizes that mutations affecting early development are almost inevitably harmful Thus he concludes that body plans once established will not change and that any subsequent evolution must occur within an established
Match 107 (1):
Reference (007940 .. 007979, of 13533):
Subject (019530 .. 019568, of 28080):
And indeed the fossil record does show a curious from a neo Darwinian point of view top down pattern of appearance in which higher taxa and the body plans they represent appear first only later to be followed by the
And indeed the fossil record does show a curious from a Darwinian point of view top down pattern of appearance in which higher taxa and the body plans they represent appear first only later to be followed by the
Match 108 (1):
Reference (007981 .. 007990, of 13533):
Subject (019570 .. 019579, of 28080):
of lower taxa representing variations within those original body designs
of lower taxa representing variations within those original body designs
Match 109 (1):
Reference (008001 .. 008024, of 13533):
Subject (019580 .. 019603, of 28080):
Further as Kauffman expects body plans appear suddenly and persist without significant modification over time But here again Kauffman begs the most important question
Further as Kauffman expects body plans appear suddenly and persist without significant modification over time But here again Kauffman begs the most important question
Match 110 (1):
Reference (008028 .. 008165, of 13533):
Subject (019605 .. 019738, of 28080):
produces the new Cambrian body plans in the first place Granted he invokes long jump mutations to explain this but he identifies no specific self organizational process that can produce such mutations Moreover he concedes a principle that undermines the plausibility of his own proposal Kauffman acknowledges that mutations that occur early in development are almost inevitably deleterious Yet developmental biologists know that these are the only kind of mutations that have a realistic chance of producing large scale evolutionary change i e the big jumps that Kauffman invokes Though Kauffman repudiates the neo Darwinian reliance upon random mutations in favor of self organizing order in the end he must invoke the most implausible kind of random mutation in order to provide a self organizational account of the new Cambrian body plans Clearly his model is not sufficient
produced the new Cambrian body plans in the first place Granted he invokes long jump mutations to explain this but he identifies no specific selforganizational process that can produce such mutations Moreover he concedes a principle that undermines the plausibility of his own proposal Kauffman acknowledges that mutations that occur early in development are almost inevitably deleterious Yet developmental biologists know that these are the only kind of mutations that have a realistic chance of producing large scale evolutionary change that is the big jumps that Kauffman invokes Though Kauffman repudiates the neo Darwinian reliance upon random mutations in favor of self organizing order in the end he must invoke the most implausible kind of random mutation to provide a selforganizational account of the new Cambrian body plans Clearly his model is not sufficient
Match 111 (1):
Reference (008201 .. 008210, of 13533):
Subject (021759 .. 021772, of 28080):
pattern of sudden appearance and stasis in the fossil record
pattern of appearance and morphological isolation that is evident in the Cambrian fossil record
Match 112 (1):
Reference (008258 .. 008281, of 13533):
Subject (005296 .. 005321, of 28080):
According to punctuationalists natural selection functions more as a mechanism for selecting the fittest species rather than the most fit individual among a species
According to many punctuationalists natural selection functions more as a mechanism for selecting the most fit species rather than the most fit individual among a species
Match 113 (1):
Reference (008286 .. 008296, of 13533):
Subject (005323 .. 005333, of 28080):
morphological change should occur in larger more discrete intervals than it
morphological change should occur in larger more discrete intervals than traditional
Match 114 (1):
Reference (008344 .. 008405, of 13533):
Subject (005656 .. 005718, of 28080):
noted that the proposed mechanism of punctuated evolutionary change simply lacked the raw material upon which to work As Valentine and Erwin 1987 note the fossil record fails to document a large pool of species prior to the Cambrian Yet the proposed mechanism of species selection requires just such a pool of species upon which to act Thus they conclude that the
note that the proposed mechanism of punctuated evolutionary change simply would have lacked the raw material upon which to work As Valentine and Erwin note the fossil record fails to document a large pool of species prior to the Cambrian Yet the proposed mechanism of species selection requires just such a pool of species upon which to act Thus they conclude that the
Match 115 (1):
Reference (008344 .. 008410, of 13533):
Subject (005656 .. 005724, of 28080):
noted that the proposed mechanism of punctuated evolutionary change simply lacked the raw material upon which to work As Valentine and Erwin 1987 note the fossil record fails to document a large pool of species prior to the Cambrian Yet the proposed mechanism of species selection requires just such a pool of species upon which to act Thus they conclude that the mechanism of species selection probably
note that the proposed mechanism of punctuated evolutionary change simply would have lacked the raw material upon which to work As Valentine and Erwin note the fossil record fails to document a large pool of species prior to the Cambrian Yet the proposed mechanism of species selection requires just such a pool of species upon which to act Thus they conclude that the probability that species selection is a
Match 116 (1):
Reference (009161 .. 009171, of 13533):
Subject (020354 .. 020366, of 28080):
the problem of the origin of form and information since the
the problem of the origin of biological information exposes a deficiency in the
Match 117 (1):
Reference (009319 .. 009332, of 13533):
Subject (000491 .. 000502, of 28080):
candidates for explaining the origination of biological form or the information necessary to produce
can account for the origin of the biological information necessary to produce
Match 118 (1):
Reference (009344 .. 009353, of 13533):
Subject (020346 .. 020363, of 28080):
approach to the problem of the origin of form specifically
a vast space of combinatorial possibilities Analysis of the problem of the origin of biological information exposes a
Match 119 (1):
Reference (009997 .. 010007, of 13533):
Subject (000227 .. 000239, of 28080):
design as an explanation for the origin of the biological information
design hypothesis from consideration as an explanation for the origin of biological form
Match 120 (1):
Reference (010001 .. 010011, of 13533):
Subject (000493 .. 000503, of 28080):
for the origin of the biological information necessary to produce the
for the origin of the biological information necessary to produce the
Match 121 (1):
Reference (010175 .. 010187, of 13533):
Subject (000037 .. 000048, of 28080):
and Lewontin 1978 have long acknowledged that organisms appear to have been designed
and Richard Lewontin acknowledge that biological organisms appear to have been designed
Match 122 (1):
Reference (010193 .. 010207, of 13533):
Subject (000061 .. 000074, of 28080):
that what Ayala 1994 5 calls the obvious design of living things is only apparent
that what Francisco Ayala calls the obvious design of living things is only apparent
Match 123 (1):
Reference (010740 .. 010764, of 13533):
Subject (014093 .. 014117, of 28080):
and philosophy of science have shown that many scientific theories particularly in the historical sciences are formulated and justified as inferences to the best explanation
and philosophy of science have shown that many scientific theories particularly in the historical sciences are formulated and justified as inferences to the best explanation
Match 124 (1):
Reference (010776 .. 010801, of 13533):
Subject (014119 .. 014142, of 28080):
Historical scientists in particular assess or test competing hypotheses by evaluating which hypothesis would if true provide the best explanation for some set of relevant data
Historical scientists in particular assess competing hypotheses by evaluating which hypothesis would if true provide the best explanation for some set of relevant data
Match 125 (1):
Reference (010813 .. 010828, of 13533):
Subject (014143 .. 014158, of 28080):
Those with greater explanatory power are typically judged to be better more probably true theories Darwin
Those with greater explanatory power are typically judged to be better more probably true theories Darwin
Match 126 (1):
Reference (010831 .. 010884, of 13533):
Subject (014160 .. 014215, of 28080):
used this method of reasoning in defending his theory of universal common descent Moreover contemporary studies on the method of inference to the best explanation have shown that determining which among a set of competing possible explanations constitutes the best depends upon judgments about the causal adequacy or causal powers of competing explanatory entities
used this method of reasoning in defending his theory of universal common descent 85 Moreover contemporary studies on the method of inference to the best explanation have shown that determining which among a set of competing possible explanations constitutes the best depends upon judgments about the causal adequacy or causal powers of the competing explanatory entities
Match 127 (1):
Reference (010977 .. 010986, of 13533):
Subject (000227 .. 000239, of 28080):
design as an explanation for the origin of biological form
design hypothesis from consideration as an explanation for the origin of biological form
Match 128 (1):
Reference (010977 .. 010988, of 13533):
Subject (014620 .. 014631, of 28080):
design as an explanation for the origin of biological form and information
design is sufficient as a causal explanation for the origin of information
Match 129 (1):
Reference (011068 .. 011080, of 13533):
Subject (019810 .. 019830, of 28080):
of hierarchically arranged systems of parts In the first place intelligent human agents
of code or hierarchically arranged systems of parts Clearly they do In the first place we know that intelligent human agents
Match 130 (1):
Reference (011091 .. 011103, of 13533):
Subject (019794 .. 019810, of 28080):
power to produce information in the form of linear sequence specific arrangements of
powers sufficient to produce such increases in information either in the form of sequence specific lines of
Match 131 (1):
Reference (011099 .. 011120, of 13533):
Subject (019836 .. 019859, of 28080):
linear sequence specific arrangements of characters Indeed experience affirms that information of this type routinely arises from the activity of intelligent agents
source invariably comes to a mind that of a software engineer or programmer
source invariably we come to a mind to that of a programmer
Match 133 (1):
Reference (011171 .. 011201, of 13533):
Subject (019917 .. 019949, of 28080):
experience based knowledge of information flow confirms that systems with large amounts of specified complexity especially codes and languages invariably originate from an intelligent source from a mind or personal agent
experience based knowledge of information flow confirms that systems with large amounts of specified complexity especially codes and languages invariably originate from an intelligent source that is from a mind or personal agent
Match 134 (1):
Reference (011203 .. 011217, of 13533):
Subject (014501 .. 014512, of 28080):
Quastler 1964 put it the creation of new information is habitually associated with conscious activity
Quastler the creation of new information is habitually associated with conscious activity
Match 135 (1):
Reference (011226 .. 011237, of 13533):
Subject (020510 .. 020521, of 28080):
the highly specified hierarchical arrangements of parts in animal body plans also
the highly specified hierarchical arrangements of parts in animal body plans also
Match 136 (1):
Reference (011258 .. 011344, of 13533):
Subject (020524 .. 020613, of 28080):
At every level of the biological hierarchy organisms require specified and highly improbable arrangements of lower level constituents in order to maintain their form and function Genes require specified arrangements of nucleotide bases proteins require specified arrangements of amino acids new cell types require specified arrangements of systems of proteins body plans require specialized arrangements of cell types and organs Organisms not only contain information rich components such as proteins and genes but they comprise information rich arrangements of those components and the systems that comprise them
At every level of the biological hierarchy organisms require specified and highly improbable arrangements of lower level constituents in order to maintain their form and function Genes require specified arrangements of nucleotide bases proteins require specified arrangements of amino acids new cell types require specified arrangements of proteins and systems of proteins new body plans require specialized arrangements of cell types and organs Organisms not only contain information rich components such as proteins and genes but they comprise information rich arrangements of those components and the subsystems that comprise them
Match 137 (1):
Reference (011258 .. 011352, of 13533):
Subject (020524 .. 020616, of 28080):
At every level of the biological hierarchy organisms require specified and highly improbable arrangements of lower level constituents in order to maintain their form and function Genes require specified arrangements of nucleotide bases proteins require specified arrangements of amino acids new cell types require specified arrangements of systems of proteins body plans require specialized arrangements of cell types and organs Organisms not only contain information rich components such as proteins and genes but they comprise information rich arrangements of those components and the systems that comprise them Yet we know based on our present experience
At every level of the biological hierarchy organisms require specified and highly improbable arrangements of lower level constituents in order to maintain their form and function Genes require specified arrangements of nucleotide bases proteins require specified arrangements of amino acids new cell types require specified arrangements of proteins and systems of proteins new body plans require specialized arrangements of cell types and organs Organisms not only contain information rich components such as proteins and genes but they comprise information rich arrangements of those components and the subsystems that comprise them Based on experience
Match 138 (1):
Reference (011374 .. 011416, of 13533):
Subject (020641 .. 020688, of 28080):
in which both individual modules and the arrangements of those modules exhibit complexity and specificity information so defined Individual transistors resistors and capacitors exhibit considerable complexity and specificity of design at a higher level of organization their specific arrangement within an integrated circuit
in which both individual modules and also the hierarchical arrangements of those modules exhibit complexity and functional specificity information so defined Individual transistors resistors and capacitors exhibit considerable complexity and specificity of design at a higher level of organization their specific arrangement and connection within an integrated circuit
Match 139 (1):
Reference (011420 .. 011434, of 13533):
Subject (020686 .. 020704, of 28080):
and reflects further design Conscious and rational agents have as part of their powers of
an integrated circuit reflects further design Conscious and rational human agents have as a consequence of their powers of
Match 140 (1):
Reference (011471 .. 011484, of 13533):
Subject (020728 .. 020747, of 28080):
we have good reason to doubt that mutation and selection self organizational processes or
we have good reasons to doubt that either the mutation selection mechanism or self organizational processes can produce such information
Match 141 (1):
Reference (011524 .. 011533, of 13533):
Subject (000227 .. 000239, of 28080):
design as an explanation for the origin of biological form
design hypothesis from consideration as an explanation for the origin of biological form
Match 142 (1):
Reference (011524 .. 011535, of 13533):
Subject (014620 .. 014631, of 28080):
design as an explanation for the origin of biological form and information
design is sufficient as a causal explanation for the origin of information
Match 143 (1):
Reference (011537 .. 011553, of 13533):
Subject (019990 .. 020006, of 28080):
agents have just those necessary powers that natural selection lacks as a condition of its causal adequacy
agents have just those necessary powers that natural selection lacks as a condition of its causal adequacy
Match 144 (1):
Reference (011559 .. 011575, of 13533):
Subject (020014 .. 020027, of 28080):
previous analysis we saw that natural selection lacked the ability to generate novel information precisely because it
arisen Natural selection can favor new proteins and genes but only after they
arisen Natural selection can favor new proteins and genes but only after they
Match 146 (1):
Reference (011598 .. 011611, of 13533):
Subject (020053 .. 020066, of 28080):
some function The job of generating new functional genes proteins and systems of proteins
some function The job of generating new functional genes proteins and systems of proteins
Match 147 (1):
Reference (011614 .. 011689, of 13533):
Subject (020070 .. 020143, of 28080):
entirely to random mutations Yet without functional criteria to guide a search through the space of possible sequences random variation is probabilistically doomed What is needed is not just a source of variation i e the freedom to search a space of possibilities or a mode of selection that can operate after the fact of a successful search but instead a means of selection that a operates during a search before success and that b is
entirely random mutations Yet without functional criteria to guide a search through the space of possible sequences random variation is probabilistically doomed What is needed is not just a source of variation that is the freedom to search a space of possibilities or a mode of selection that can operate after the fact of a successful search but instead a means of selection that a operates during a search before success and b is
Match 148 (1):
Reference (011693 .. 011747, of 13533):
Subject (020142 .. 020201, of 28080):
about or knowledge of a functional target Demonstration of this requirement has come from an unlikely quarter genetic algorithms Genetic algorithms are programs that allegedly simulate the creative power of mutation and selection Dawkins and Kuppers for example have developed computer programs that putatively simulate the production of genetic information by mutation and natural selection
b is informed by knowledge of a functional target Demonstration of this requirement has come from an unlikely quarter genetic algorithms Genetic algorithms are programs that allegedly simulate the creative power of mutation and selection Richard Dawkins and Bernd Olaf Kuppers for example have developed computer programs that putatively simulate the production of genetic information by mutation and natural selection
Match 149 (1):
Reference (011767 .. 011859, of 13533):
Subject (020220 .. 020314, of 28080):
these programs only succeed by the illicit expedient of providing the computer with a target sequence and then treating relatively greater proximity to future function i e the target sequence not actual present function as a selection criterion As Berlinski 2000 has argued genetic algorithms need something akin to a forward looking memory in order to succeed Yet such foresighted selection has no analogue in nature In biology where differential survival depends upon maintaining function selection cannot occur before new functional sequences arise Natural selection lacks foresight What natural selection lacks intelligent selection
these programs only succeed by the illicit expedient of providing the computer with a target sequence and then treating relatively greater proximity to future function that is the target sequence not actual present function as a selection criterion 123 As David Berlinski has argued genetic algorithms need something akin to a forward looking memory in order to succeed 124 Yet such foresighted selection has no analogue in nature In biology where differential survival depends upon maintaining function selection cannot occur before new functional sequencing arises Natural selection lacks foresight What natural selection lacks intelligent selection
Match 150 (1):
Reference (011864 .. 011879, of 13533):
Subject (020317 .. 020328, of 28080):
design provides Rational agents can arrange both matter and symbols with distant goals in mind In
design provides Agents can arrange matter with distant goals in mind In
Match 151 (1):
Reference (012037 .. 012069, of 13533):
Subject (020352 .. 020383, of 28080):
Analysis of the problem of the origin of biological information therefore exposes a deficiency in the causal powers of natural selection that corresponds precisely to powers that agents are uniquely known to possess
Analysis of the problem of the origin of biological information exposes a deficiency in the causal powers of natural selection that corresponds precisely to powers that agents are uniquely known to possess
Match 152 (1):
Reference (012037 .. 012073, of 13533):
Subject (020352 .. 020387, of 28080):
Analysis of the problem of the origin of biological information therefore exposes a deficiency in the causal powers of natural selection that corresponds precisely to powers that agents are uniquely known to possess Intelligent agents have foresight
Analysis of the problem of the origin of biological information exposes a deficiency in the causal powers of natural selection that corresponds precisely to powers that agents are uniquely known to possess Agents do have foresight
Match 153 (1):
Reference (012037 .. 012090, of 13533):
Subject (020352 .. 020404, of 28080):
Analysis of the problem of the origin of biological information therefore exposes a deficiency in the causal powers of natural selection that corresponds precisely to powers that agents are uniquely known to possess Intelligent agents have foresight Such agents can select functional goals before they exist They can devise or select material means to
Analysis of the problem of the origin of biological information exposes a deficiency in the causal powers of natural selection that corresponds precisely to powers that agents are uniquely known to possess Agents do have foresight Agents can also select functional goals before they exist They can devise or select material means to
Match 154 (1):
Reference (012100 .. 012110, of 13533):
Subject (020416 .. 020426, of 28080):
and then actualize those goals in accord with a preconceived design
and then actualize those goals in accord with a preconceived design
Match 155 (1):
Reference (012128 .. 012184, of 13533):
Subject (020433 .. 020487, of 28080):
The causal powers that natural selection lacks almost by definition are associated with the attributes of consciousness and rationality with purposive intelligence Thus by invoking design to explain the origin of new biological information contemporary design theorists are not positing an arbitrary explanatory element unmotivated by a consideration of the evidence Instead they are positing an entity
The causal powers that natural selection lacks almost by definition are associated with the attributes of consciousness rationality and purposive intelligence Thus by invoking intelligent design to explain the origin of new information design theorists are not positing an arbitrary explanatory element unmotivated by a consideration of the evidence Instead they are positing an entity
Match 156 (1):
Reference (012186 .. 012205, of 13533):
Subject (020489 .. 020508, of 28080):
precisely the attributes and causal powers that the phenomenon in question requires as a condition of its production and explanation
precisely the attributes and causal powers that the phenomenon in question requires as a condition of its production and explanation
Match 157 (1):
Reference (012230 .. 012239, of 13533):
Subject (020822 .. 020832, of 28080):
the most causally adequate explanation for the origin of the
the best most causally adequate explanation for the origin of the
Match 158 (1):
Reference (012275 .. 012284, of 13533):
Subject (020354 .. 020366, of 28080):
the problem of the origination of biological form and the
the problem of the origin of biological information exposes a deficiency in the |
Everybody talks about their desert island soundtrack. But what about desert island kitchen tools? We took the question to a survivalist for some very honest answers.
What kitchen gear would you want with you on a desert island? The question came up for the Epi staff in a recent meeting. There was talk of expensive blenders and Big Green Eggs until the conversation shifted. No, really, somebody said. What if you were really stranded?
I gave Creek a hypothetical situation: if you were trapped on an actual desert island, what are the kitchen tools you'd take with you? He didn't even have to think about it. “What we eat out in the wilderness isn’t about taste or looks,” he said. Instead, it's all about survival.
Here are the six tools he recommended.
Meet the Epicurious Castaway Cook.
Illustration by Tommy Werner
A Metal Salad Bowl
In our cushy office tower, the Epi Test Kitchen leans on giant metal mixing bowls for mixing salads, whisking baked goods, and melting chocolate. In the wild, they’d make the difference between life and death. Metal is light and conducts heat well, making it useful for quickly boiling water. “It’s not the most exciting tool, but I’ll tell you what: there’s nothing we take for granted more than a container in our everyday lives,” says Creek. And let’s be real: could you really melt chocolate using a palm tree bowl?
The sun, the beach, the fresh seafood—being stuck on a desert island could have its perks. But to actually catch that fish, you'll need a spear (or gig, as Creek calls it). That's where a grill fork (that long, trident-looking fork that came with your grill kit) comes in. It's usually used for piercing large cuts of meat, but you're going to use it to spear fish (Creek suggests sharpening the fork on sandstone first.) Note: This may be the only case where a grill fork is actually useful.
The castaway cook doesn't use olive oil for just cooking.
Illustration by Tommy Werner
A Plastic Bottle of Vegetable Oil
Some kitchen fats can last up to a month as candles or rudimentary tiki torches, like Crisco, which can make a 30-day candle. To make one of these oil torches, take a wad of palm fibers from a palm tree and cram them into the split end of a stick. Douse with oil and ignite the fibers to light a shelter, or, if you’re a real pro, wade out into water at nighttime and use the light to spot sleeping fish. "That's the best time to go fishing," says Creek.
And when you're out of oil, put the bottle to use: cut the plastic bottle in half and leave the cap on. Slit the sides of the bottle vertically and fold those sides open like a flower. Burrow the top of the bottle capside-down in the sand. That’s your collector cup. With how common pop-up storms on islands are, this water collector has so much more surface area than just leaving the bottle open without the cap on. “Imagine 50, 60, 70 of these stuck in the sand just waiting for the next pop-up storm,” says Creek, “Take a reed straw after a storm and go drink these!” Hello, open bar.
A Sheet of Aluminum Foil
The signalling mirror is a staple for military survival kits, and Creek claims it is hands-down the best tool for getting rescued. In a pinch, aluminum foil can make a great substitute. Some signal flashes can be seen up to 3 miles away by a plane, even by the light of the moon. So there is actually hope as long as you shine on.
Your wine glass might just save your life.
Illustration by Tommy Werner
A Wine Glass
No, the wine glass is not for a minerally white wine to pair with your coast-sourced clams. “Bulbous containers like a wine glass or the rounded top of a 2-liter bottle are going to be the easiest way to start a fire,” says Creek. Fill the bulb with water to focus sunrays onto flammable tinder, and boom—you've got flames. Plastic wine glasses work here (and are less breakable), but grab one with a stem—it frees up your hands for guiding the fire. Or, you know, playing with your volleyball best friend. |
A decade ago, the federal Energy Information Administration predicted that the installed capacity of wind turbines in the United States would, at best, reach 20,000 megawatts by 2020. It was one of the EIA's patented underestimates of renewable energy sources. This morning, the American Wind Energy Association (AWEA) released its annual report [pdf]. Installed U.S. wind capacity as of December 2009: 35,000 megawatts. Of that, 10,000 megawatts were installed in 2009, the most in U.S. history, and 39% of the total new electricity-generating capacity installed last year, second behind natural gas. Some 3000 megawatts are currently under construction. Wind power now generates 1.8% of all U.S. electricity.
Without grants from the Obama administration's American Recovery and Reinvestment Act – the stimulus package – many of those new turbines now cranking power out to residences and businesses would be sitting in warehouses. And many of the 85,000 Americans employed in the wind industry in all 50 states would be in the unemployment queue.
Fourteen states have now joined the wind power "gigawatt club," that is, at least 1,000 megawatts of installed capacity. In 2008, only seven states could make that claim. In 2005, only two could. The top three? Texas, Iowa, and California. While everybody would expect the two giants to be on that list, Iowa has a bigger claim to fame than either of them. Thanks to far-sighted state policies that saw the state's first big wind farm installed at Storm Lake in 1999 when EIA was downplaying the future of wind, turbine farms and other wind installations now generate 14.2 percent of Iowa's electricity.
But, while the United States has again recaptured the lead in wind-turbine installations, tripled the number of manufacturers who install turbines to 15 in just five years, and managed with the help of the stimulus package to beat expectations during the recession, there are obstacles ahead. These include the need for new and upgraded transmission lines and nimbyism. But the chief stumbling block is the myopic lack of a federal policy that levels the playing field for expansion of wind and other renewable energy.
Needed is a federally mandated "renewable energy standard," an RES. Of all the OECD countries, the United States and Canada are the only ones that don't have an industrial policy that includes RES targets for 2020. All of Europe, Japan, Korea, India and China have set targets. As Sarah Howell, AWEA's vice president for public affairs said at a press conference Thursday, there is an ongoing race between U.S. policies and the policies of other countries when it comes to wind. Remaining competitive in this market will require a different approach in Washington.
Over the years, the failure to establish an RES created a boom-and-bust cycle for wind energy in the United States. Federal production tax credits have been highly beneficial to the industry. But these have had to be renewed by Congress every one or two years. They have sometimes expired, only to be revived at some future date. This has made it impossible for the industry or potential customers to make firm plans. And, even though the modern wind energy industry started in the United States in the 1980s, failure to set a long-term policy meant that other countries, like Denmark and Germany, leaped ahead in manufacturing and installations, respectively. As Denise Bode, CEO of the AWEA says, the wind sector "needs long-term policy certainty and market pull in order to grow."
The myopia that has afflicted U.S. energy policy for three decades had a chance for some correction in 1999 when Secretary of Energy Bill Richardson presented the Comprehensive Electricity Competition Act to Congress. Among other things, this included a federal "renewable portfolio standard" requiring that a certain level of future electricity come from renewable sources, including wind. Congress didn't go for it. Last year, as part of its comprehensive energy bill, the House of Representatives finally approved an RES of 20 percent by 2020. But the Senate is still wrangling with its version.
Last month, the Governors' Wind Energy Coalition, a bipartisan group of chief executives from 29 states, called on Congress to quickly pass an RES. A new study, the Jobs Impact of a National Renewable Electricity Standard, conducted by Navigant Consulting, Inc., found that a 25% by 2025 national RES would generate 274,000 more renewable energy jobs over a no-national RES policy.
Lower carbon emissions, added U.S. manufacturing operations, more jobs and a potential bonanza in exportable products make an RES a no-brainer. But it was a no-brainer in 1999, too, and not enough members of Congress showed they had the brains to make it happen. Is it too much to hope that the Senate shows it's learned something since then? |
// name: TupleOperation4
// keywords:
// status: correct
// cflags: -d=newInst
//
function f
input Real t;
output Integer n1 = 2;
output Integer n2 = 3;
end f;
model TupleOperation4
Real x[3];
Real y;
equation
y = x[f(time)];
end TupleOperation4;
// Result:
// function f
// input Real t;
// output Integer n1 = 2;
// output Integer n2 = 3;
// end f;
//
// class TupleOperation4
// Real x[1];
// Real x[2];
// Real x[3];
// Real y;
// equation
// y = x[f(time)[1]];
// end TupleOperation4;
// endResult
|
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The contributions of Usher and others to the elimination of tension from groin herniorrhaphy.
Relaxing incisions (Wolfler 1892) were eventually shown (Read and McLeod, 1981) to reduce but not eliminate wound tension after sutured herniorrhaphy of the groin. Reinforcing prosthetics became widely shunned because of morbidity until Usher et al (1958) introduced polyethylene, then polypropylene mesh (1963) for preperitoneal tensionless repair of large defects. Excellent long-term results were obtained, with his technique, by Collier and Griswold (1967). Patt (1967) envisaged its application to primary hernia. Reis (1899) introduced early ambulation. However, it was not until Leithauser (1943), Blodgett (1946), and others showed immediate rising accelerated wound healing and reduced complications that Farquharson (1955) began outpatient hernioplasty (in 1950) under local anesthesia (Cushing 1900). Bellis (1964) followed, performing tensionless repair in 25%. Rodriguez and Phillips (1967) described office herniorrhaphy, 30% undergoing polypropylene mesh coverage without tension. Lichtenstein (1970) reported mesh onlay reinforcement for sutured repair of large defects, discharge was within 24 hours. Martin et al (1982) began (in 1972) to treat all inguinal herniation in adults with polypropylene mesh "to avoid recurrences". Newman did likewise, using tension-free placement (Rodriguez et al) in the subaponeurotic plane. Encountering resistance to publication ("real surgeons don't use mesh") he, in 1980, asked Lichtenstein to publish and popularize the technique. Kelly (1898) introduced plug prosthestic repair of femoral herniation. Drainer and Reid (1972) used polypropylene mesh from below under local anesthesia. Lichtenstein and Shore followed, treating recurrent inguinal defects similarly. Gilbert (1989) applied the technique to indirect herniae. Usher and others deserve recognition for their contributions to the elimination of tension from herniorrhaphy. |
Last updated on .From the section Cricket
Kevin O'Brien's blistering century helped Ireland beat England in the 2011 World Cup
Ireland and Afghanistan have been granted Test status by the International Cricket Council.
It increases the number of countries competing at the top level of international cricket to 12.
They are the first admissions since Bangladesh gained Test status in 2000.
The two countries, who already have one-day and Twenty20 international status, have enjoyed notable successes against Test-playing nations in global competitions in recent years.
Ireland, who are 12th in the ICC one-day rankings external-link , beat England in the 2011 World Cup, four years after a shock victory over Pakistan in the same competition.
Afghanistan, currently 10th in the rankings, drew an ODI series with T20 world champions West Indies this month.
The changes were passed unanimously at the ICC full council meeting at The Oval.
What next?
'The drinks are on you' - Ireland celebrate gaining Test status
Ireland captain William Porterfield says it will be a "special day" if he leads his side out for their first Test.
Wicketkeeper Gary Wilson described it as a "historic day", writing on Twitter: external-link "Years worth of work feels like it has been recognised. Here's to the beginning."
Cricket Ireland chairman Ross McCollum said: "We will start discussions with several parties about staging our first Test.
"We are sincerely grateful to the ICC and its members for giving us this honour.
"It is a recognition of the quality of our teams over the years, male and female, of our talented administration, and of the strength of our domestic and club structures."
When each nation became a full member, thus gaining Test status England (founder member) 1909 Australia (founder member) 1909 South Africa (founder member) 1909 India 1926 New Zealand 1926 West Indies 1926 Pakistan 1952 Sri Lanka 1981 Zimbabwe 1992 Bangladesh 2000 Ireland 2017 Afghanistan 2017
'The entire nation will be celebrating'
Afghanistan's rise has been rapid - the cricket board was only formed in 1995, by Afghan refugees living in Pakistan, but the country gained full ODI status in 2011 and became an ICC associate member in 2013.
They beat West Indies in reaching the Super 10 stage of the World Twenty20 last year.
Afghanistan beat Ireland by an innings and 172 runs in a four-day Intercontinental Cup in March in April.
Leg-spinner Rashid Khan and off-spinner Mohammad Nabi both impressed in the recent Indian Premier League; Khan was the sixth highest wicket-taker in his debut campaign with 17 scalps.
Both broke into the top 10 of the ODI bowling rankings during the recent tour of the West Indies, when Khan took 7-18, the fourth best ODI bowling figures in history.
Afghanistan Cricket Board chief executive Shafiq Stanikzai said: "For a nation like Afghanistan it is a huge and remarkable achievement.
"The entire nation will be celebrating across all five regions and different provinces - it is the perfect Eid gift." |
Told he was being "silly", Mr Jenkin hit back: "I bet you're going to treat Leon Brittan with a lot more deference than you treat me because the BBC is not exactly a haven for Eurosceptics as we know |
Watching the trailer for Lawrie Brewster’s The Unkindness Of Ravens is a bit of an experience in itself. It’s an eye-popping few minutes that smashes folk horror, action, and extreme levels of gore to the extent that is truly impressive, and we absolutely can’t wait to see it at Horror Channel FrightFest. This trailer is EXTREMELY NSFW, so…be warned.
“Andrew Alburn, a homeless veteran suffering from PTSD, is plagued by flashbacks of a traumatic event he witnessed while serving in the armed forces. He retreats to the remote Scottish Highlands hoping to overcome his fear of Ravens, the dark creatures that populate his visions, but, in this bleak wilderness, his nightmares manifest into an enemy more powerful than he could ever have imagined. He must battle these monstrous entities as well as his inner demons to keep his life, and reclaim his sanity.”
With the FrightFest screening fast approaching, Brewster talked to us about what horror fans can expect from his film, his inspirations, his Kickstarter experience, and blending The Wicker Man and Hellraiser.
What would be your quick “Come and see this film!” pitch to the FrightFest audience?
Those who come to our première will bear witness to an unimaginable battle for survival as a broken ex-soldier passes through the very gates of hell. There he will mount a last stand against a nightmare nemesis of unrelenting cruelty and perversion in a horror-epic that combines the insanity of Apocalypse Now with the dread claustrophobia of The Evil Dead.
How did this film come about? Was it something that you and writer Sarah Daly had been working on for a while?
Me and Sarah are genuine collaborators on the creation of unique horror worlds and and strange antagonists. We express this passion for originality and our love of the horror genre through our production company Hex Media. Following our first film Lord Of Tears, featuring the Owlman, which was a classic Gothic style chiller, we wanted to explore a new path with The Unkindness of Ravensbased around the idea of creating a gritty, violent and down to earth portrayal of psychological intensity and nightmarish cosmological horror. We took inspiration from a myriad of sources, from ancient Celtic and Norse mythology to the subversive era of 70s cinema reflected by films such as Don’t Look Now, The Wicker Man and Straw Dogs.
As part of the development for the film we envisaged an ambitious post-production schedule that would allow us to create this wider nightmare world that our hero finds himself in, which includes all manner of practical and traditional effects. So it is our most ambitious film to date and one that we have been working on for far too long. Now we’re just thrilled to have the opportunity to share it with our fellow fans of the genre!
Jamie Scott Gordon as Andrew
It looks like there are quite a few horror elements swirling about in this movie: some quite heavy gore, some action, some folk horror and a lot more besides! Had you always conceived it as this intense mix?
Me and Sarah are both enormously passionate about the folk horror sub genre and are eager proponents of it’s resurrection in modern horror. Because me and Sarah are from from Scotland and Ireland respectively, we have found great inspiration from the ancient Celtic culture of our nations which provides a rich resource of delicious Pagan horror which we like to combine with the esoteric and cosmological ideas of HP Lovecraft. We aim to make our films present to the audience a brief window into the limitless unknown – a brief flash of the nightmarish possibilities of our limitless universe.
As great fans of the horror genre, we’ve drawn some influences from other horror movies we love. Some of them might almost seem like contradictory influences too, for example the film has the claustrophobia of The Evil Dead, but the epic and nightmarish visceral quality of Hellraiser. But the film also has a serious drama side that might remind folks more of films like Kill Listand Jacob’s Ladder. We also have a very hard edged pagan influence to the film that definitely will remind some people of The Wicker Man… basically imagine The Wicker Man and Hellraiser combined into some kind of heinous screaming beast and you’ll be about there.
Purely on a practical level, this movie looks hugely ambitious! What were the biggest challenges in terms of actually getting it made?
Oh, where to begin! I just remember that in pre-production I was a muscular Adonis of man gleaming before the sun but now, after years of production and post-production I am but a humble shell. A Kinder egg bereft of any toy! Some of the greatest challenges were also the most amusing in an albeit perverse manner, (like how Vincent Price might be amused in The Masque of the Red Death!) Which was the scenes that comprised of almost fifty naked extras wrapped in steel chains covered in blood, trudging along a freezing cold Scottish beach while clubbed and beaten by giant black armoured Raven headed warriors.
From organising ambitious scales of production to the careful patience required when working with crows (not the most cooperative of actors – though a little more affordable in the catering department.)
There is not enormous support in the industry for horror films that break from the standard commercial formula, so it was a challenge to finance our film and get it made. Thankfully we had the support of Sultan Saeed Al Darmaki of Dark Dunes Productions and the kindness and courage of all our fans and supporters at Kickstarter which made the life or death difference to our film getting completed.
Andrew is obviously an unreliable narrator for the viewer. I imagine that’s a lot of fun to play with but is it also tricky in terms of keeping a grip on the story?
This is an interesting question because it calls not just the characters role as a narrator into question but that of the film-maker. For us it is an essential priority for a filmmaker to keep a grip on the story, especially with a psychological horror film which at times will present the audience with interesting questions as to the psychological or supernatural interpretations of the events which unfold for our character.
This is because if it does not retain that grounded sense of a story by the fire, then it becomes lost in its own abstraction. It is my sincere intention and hope that audiences who share a different interpretation of our film will leave satisfied that there is a well rounded story with a satisfying and epic finale that doesn’t leave audiences scouring around IMDb for clues on what the hell actually happened.
You’ve worked with Jamie Scott-Gordon before; did you always have him in your head as Andrew?
Yes, Jamie Scott-Gordon is an exceptionally gifted and passionate actor who cares very much for the characters he inhabits. While performing as a soldier suffering from PSTD, he worked with veterans to prepare and understand the condition they live with. Even going to the incredible lengths of sleeping homeless on the streets of Edinburgh like his character does, to truly experience the emotions and reactions of those often abandoned by society. I cannot think of many young actors like this and so, following his performance in Lord of Tears, I felt compelled to take his enthusiasm for method and characterisation further with our most intense character yet.
You did a Kickstarter to help fund post-production. How did you find that experience?
I believe the mainstream is becoming more and more narrow in the kinds of films it produces. To recoup their huge budgets they need to tell stories with mass appeal – and that’s fine – but it means that mainstream cinema no longer creates risky, original content. More than ever, it’s up to independents to tell those kinds of stories. Kickstarter allows niche audiences to decide what they want to see, and lets them help bring those projects to life. It’s an important source of funding for stranger, riskier films, and I think its success proves that audiences do feel starved of original content.
If it weren’t for places like Kickstarter, films like ours that don’t have big named actors or well-known branding would really struggle to get funded and produced. So, that’s a big reason. Also, we love the way that Kickstarter lets us connect more closely with our audience – you find a lot of kindred spirits who are hungry for the same kinds of stories as you are, and it really bolsters you through the often lonely and difficult process of making and marketing a movie to know that they’re on the journey with you, supporting what you’re trying to do.
How exciting is it to have The Unkindness Of Ravens ready to show the FrightFest audience?
Well, most of all it’s a massive honour because this is not just an ordinary audience but instead represent the greatest fans in the genre. That is folks who are so supportive and enthusiastic for the genre that they actually get out there to support independent film and great events which as any film festival owner can probably tell you – are bloody challenging and expensive to maintain.
So we are humbled that we have an opportunity to share our film with the fans just like us, and are eternally grateful to the programmers Ian Rattray, Paul McEvoy and Alan Jones for having enough faith in our film to present it at Frightfest.
What’s next for you?
Well, we’re currently producing a slate of films in conjunction with Dark Dunes Productions. The next of these is Automata, which we’ve actually already shot and hope to finish some time next year. We’ll also be shooting two more films next year as well as working with other directors to produce an anthology of horror shorts. It is our ambition to make our Scottish company Hex Media into an independent horror studio, the ‘Hammer’ of the North, you could call it, and goodness knows we’ll appreciate any help out there to achieve that.
Do you remember what your first horror movie experience was?
Apart from trying to lose my virginity in a near empty cinema to a screening of In and Out starring Kevin Kline, I would have to say it was watching classic supernatural thrillers with my paranormal obsessed mother. Films such as The Innocents and The Haunting left a lingering impact that really brought home the terror of the mind and the unknown.
Finally, which horror movie do you love that you wish more people had seen?
Perhaps not technically a horror film but god knows it feels like one to me, Threads directed by Mick Jackson closely followed by Kairo directed by Kiyoshi Kurosawa.
The Unkindness Of Ravens plays at Horror Channel FrightFest on Saturday 27 August and you can find ticket information here. |
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ACRYLIC TRAYS
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We have on offer an exceptional choice of sizes and shapes so no matter what your shower design we are confident we can find an acrylic tray to complement it.
THE VARIETY OF SHOWER TRAYS USING ACRYLICS
Don’t forget that you can choose the depth as well as the size and we also supply slim-line versions for the minimal look; the choice is yours, If you should be suffering from a lack of space take a look at acrylic pentangle or quadrant trays which can often allow a shower to be installed where a squarer shape would not necessarily fit. A little bit of imagination can go a long way when it comes to design so take your measurements and then check out our range, there is sure to be something there to fit the bill.
Choosing an acrylic shower tray is also a very cost effective way of updating your bathroom, never more so than when you purchase one from the Bathroom Discount Centre so this is definitely one of those win-win situations we all like to achieve. |
Behind the Scenes at the Iran Talks & Donald Trump's Money
Over months of negotiations at the Iran nuclear talks, several key players are people you've never heard of including the head of the Atomic Energy Organization of Iran Ali Akbar Salehi. David Sanger explains the vital role he played. Plus, Indira Lakshmanan reports on the intense negotiations between Secretary of State John Kerry and his Iranian counterpart Javad Zarif. |
Motorcycle wreck by lake impacting traffic
Travel with caution in the Saltillo area.
Medics and Care flight are responding to a motorcycle crash near Lake Lamar Bruce in Lee County.
Saltillo police are directing traffic to help get the helicopter in, said Saltillo police’s Prentiss Brown.
Sheriff Jim Johnson said there are no fatalities reported. |
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The bedbugs have made me into a better Buddhist. Or Catholo-Buddhist. Or whatever mish-mash of “religions” I’ve become.
Here’s why: I have been a disciplined practitioner of eliminating my attachment to earthly things over the past days.
Meaning I have thrown out A LOT of stuff in a very short period of time. To quantify: One dumpsterful plus a double-load for bulk pick-up.
I thought it would be interesting to explore some Buddhist and Christian quotes on attachment and “worldly” living, made all the more interesting thanks to my new frenemies (props to Eric Calvert), the bedbugs.
Starting with this Buddhist quote:
The greatest generosity is non-attachment.
So, I’m being generous to the city dump, since no one wants my bedbuggy stuff? (Well, I suppose that’s not technically correct. See here for more on people who grew attached to my stuff, thereby taking on my former attachment with the added bonus of bedbugs.)
This next quote (also Buddhist) unmasks the illusion of the uniquely human trait–saving face:
The greatest wisdom is seeing through appearances.
This is a special shout-out to any of my neighbors still speaking to me, after the several days of trash piled on my front lawn, followed by the dumpster sitting in my driveway after that. Now, we’re just back to the small pile of mulch at the bottom of the driveway, with several small trees growing out of it.
Hey, what can I say, that mulch pile was several feet high at the start of the summer. That’s what I call progress! So, even though I appear to be “that neighbor,” I’m really an extremely upstanding citizen wholly focused on saving the world, starting with absolute bedbug elimination.
Here’s one from the Bible:
You adulterous people! Do you not know that
friendship with the world is enmity with God? Therefore whoever wishes to be a
friend of the world makes himself an enemy of God.
(James 4:4 (ESV))
Ignore the first part. It’s just a pithy lead-in to the meat. What this quote really means is that I am VERY close to God. I now despise my worldly possessions. Every time I throw a new load in the dumpster, I both curse AND say a little prayer. No matter that it mostly focuses on a swift death to all bedbugs in my near vicinity.
To further emphasize my hatred of my worldliness, all of my earthly possessions are now encased in giant trash bags, so that I cannot even tell what they are. It’s now as if I own almost nothing. I am no longer a friend to the temptations of acquisition. Less is more, because it means fewer bedbugs and less hassle for me.
I’ll admit that I have felt a bit like Job with this bedbug business. Why me, God? I didn’t do anything (seriously) wrong!
Much like Job’s protests, mine haven’t done anything to change my circumstances. Life happens, and it’s up to us to figure out how to deal with it. For now, apparently the best course of action is to downsize.
(P.S. Out of sheer curiosity, I did check for Biblical and Buddhist references to bedbugs and found none (although a host of other insects, including white ants, do crawl into certain verses). But I did find this interesting commentary on whether or not Buddhists are permitted to kill bedbugs. The post also explores some interesting thoughts on what it means to be reborn as a bedbug. Wow.)
How did we get them? Who knows. Possibly through my travel or from a patient of my husband’s. We’re not dirty people, but there’s nothing like bedbugs to make you feel downright gross. It’s an instant source of shame. So pleasant to let your friends and family know about your newest guests, and how they can identify them under their own mattresses, behind pictures and electrical outlets, etc., etc.
Bed bugs are THE most difficult pest to treat, according to 76 percent of survey respondents, more so than cockroaches, ants and termites. As for where infestations occur, residences top the list with 89 percent of pest professionals treating bed bug infestations in apartments/condos and 88 percent treating bed bug infestations in single-family homes. Respondents also report other common areas, with 67 percent treating bed bug infestations in hotels/motels, 35 percent in college dormitories, 9 percent on various modes of transportation, 5 percent in laundry facilities, and 4 percent in movie theatres.
Did you read that? Why yes, it’s entirely possible that we got them from a movie theatre. But most likely, from my travel and overnights in hotels.
And, not surprisingly:
[T]he emotional and mental toll of experiencing a bed bug infestation can be severe and should not be taken lightly. Survey respondents report that 99% of clients who have had bed bugs were “upset and concerned” and 77% said such customers were “very upset and concerned.”
No doubt. Believe it. This is no fun. I think that I am better at imagining things are okay than my husband is. He hasn’t slept for nights. It’s not the bugs bugging him. We’ve only found a handful of them, truth be told. We are not in the “infestation” category by any means. But the worst thing about it is thinking about all of the potential consequences if left untreated. And the reason they’ve become more prevalent is because a lot of people cannot afford to treat them so just leave them be.
It’s the thought of the bugs, including where they are now and where they will be hiding tomorrow, underneath or behind something where we cannot see them.
And it’s the reactions of people once they find out that you have them. Many make the assumption that it has something to do with your hygiene…that it’s in some way YOUR fault. The truth is that bedbugs don’t discriminate: They like everyone’s blood, whether clean or dirty. They only come out at night, and what attracts them is warm-blooded people. The suckers are miniature, diabolical vampires.
Because of all this we are taking DRASTIC measures. Yes, I do mean DRASTIC. They must and will die. We are paying $3,200 for a combined heat and chemical treatment conducted by a professional exterminator. Here’s what they do:
Heat up each area of the house to a sustained temperature of 120 degrees. This will kill most of them.
Apply pesticides that kill the remaining bugs, including any eggs. (Did you know that they can lie dormant for 18 months? Just think of it…)
And then, we wait to see if they reappear. Because they are also killed by temperatures below 23 degrees, we are seriously considering a safety net treatment of our own in the winter, which will begin with us draining out our pipes, opening the windows, and leaving the house for a day.
Here’s what WE have to do before the exterminators begin their work:
Throw out and/or move out a bunch of stuff. Not because it has bedbugs, but because there’s a combined supply of an extra house’s worth of furniture and all-around stuff in the basement of our house, which we recently bought from my in-laws and where my nephew lived for a couple of years. As of this moment, my front yard is channeling the theme song from “Sanford and Son.” It’s full of items for the dumpster, which will arrive tomorrow. (More about my neighbors’ reaction to this in a minute.)
Wash everything–clothes, linens, furniture covers, anything fabric. Put it into sealed plastic bags. If it’s clothing that cannot be washed, dry it for 20 minutes at the highest possible heat. I even washed balls of yarn that I haven’t yet used for knitting.
Everything we wear out of the house at this point comes from a sealed plastic bag that ensures the clothing is bedbug-free. Everything. I cannot reinforce how much of a pain this is.
Vacuum everything, everywhere. Put bedbug covers on the beds. Do some spot treatments in the rooms where we’ve seen the bugs.
Repeat everything above as many times as necessary until it’s time for the exterminators.
Move all furniture away from the walls in every room and pray that our veneered furniture survives 120 degrees.
While the exterminators do their work, we get to go on a special bedbug vacation! Translation: We rent an affordable somewhat nice nearby hotel for two nights because we have to be away for that long. And we cancel our camping trip to Kelley’s Island, because instead we’ll be here doing post-exterminator cleanup.
So, this is going to be a $3,500 proposition all told. Cha-ching.
The significant effed-upness of this was on my mind today when my husband told me that neighbors had called our area commission to complain about the furniture in our front yard. Bite me. We spent all day on Sunday getting it out there and the dumpster is coming tomorrow.
Our biggest mistake was our honesty in letting people know (and putting signs on the stuff) that NO ONE SHOULD TAKE IT because of the bedbugs. I’m convinced that this is the reason for the hulabaloo. How many people in our sort of upscale Columbus neighborhood have had bedbugs and not told their neighbors? I’m guessing more than a few.
And then we have the other side of the continuum. What percentage of the population will take furniture that possibly has bedbugs? From my personal estimation, a significant and disturbingly large number of not so discriminating fellows (all men, it’s true). In one situation, a man took a table that he was going to give to his daughter. Two hours later, I noticed that he’d brought the table back. Smart daughter!
There were probably 20 people who took furniture from the yard yesterday, even though it was clearly marked and we verbally warned them. And when I went out to the car this morning, at least a few people had gone through the piles and taken even more. I have to say that I was pretty shocked. Clearly, not enough people have been through this to know the real deal of bedbug removal. It ain’t pretty.
People don’t listen, and they don’t want to. They do not take this seriously. I’ve got spraypaint all over much of the furniture and on all of the trash bags with clothes and fabric stuff. And now we have some schmuck calling us to complain about our irresponsibility?
Bite me. Better yet, bedbug bite me.
We did talk with someone from the Columbus Health Department earlier today (after a very unhelpful call with them last week when they referred us to their website), and while at least this time they were available, they actually suggested that we have the furniture destroyed. My husband asked if a bonfire would work. I don’t think this is what they had in mind. Then on second thought, they said that what we’d done in terms of marking the furniture would do the trick. I’m glad we did the right thing, as embarrassing as it has been.
If I were not a nice person, I would wish the curse of these bedbugs on the person who called the commission. I guess it’s just one of those situations where you try to do the right thing and you just can’t please everyone all of the time.
I told a friend tonight that I’m going to install my 74-year-old father from SE Ohio on the front lawn. He will in no uncertain terms and with a highly unpleasant attitude tell nosy and judgmental neighbors to mind their own bedbugging business. In less polite words than that.
When my grandmother was 14, she finished school, at eighth grade. Her mother had just died of tuberculosis, and being the only child on a farm her hands were needed for work. Two years later, she got married, and at the age of 17 she had her first of seven children.
I was thinking about my grandmother’s reality, and fully realizing how different it is from my own. There’s a picture of her at 16, with my grandfather, beside an old Model-T. It was the 1930s, and they look a lot like Bonnie and Clyde. Somewhat rakish, and definitely adventurous. Grandma had attitude.
And she also had substance. If she’d been born more recently, my grandmother would have earned her Ph.D. She was a very smart woman–intellectual, despite a humble upbringing and spending most of her life raising children and working in the house. After they were all grown up, she began researching the family genealogy and contacted people from around the world to piece it together. She did extensive research at the OSU libraries during the early 1960s, sifting through county records without the benefit of digitized information.
Grandma also had an incredible imagination and was known for her detailed stories about her family’s history in the Salt Creek Valley, along the border of Ross and Vinton Counties in Southeast Ohio. All of the stories had elements of truth, along with varying degrees of embellishment depending upon the day. They held nuggets of family history, but they also made for good entertainment. There’s a volume that my aunts put together, after transcribing hours of Grandma’s storytelling, and it’s more than 100 pages. I had the pleasure of reading from it as part of her eulogy when she passed a few years ago.
None of Grandma’s children, my aunts and uncles, went to college. In fact, neither of my parents did, but since I loved school they encouraged me to do well there and always made it clear they’d find a way to support me in earning a degree. Which they did, and not without difficulty. My mother has always been a reader, and my dad has a lot of my grandma’s innate intellectualism (with lots of blue-collar flair). They provided me with the self-confidence and resources to “make it.”
The difference between my life and my grandmother’s has to do with EDUCATIONAL OPPORTUNITY AND AN ETHIC OF SELF-SUFFICIENCY. If her family hadn’t lost it all in the Great Depression (i.e., if they’d had anything to fall back on), if she’d married and had children later in life (i.e., birth control) , she’d have finished high school. And perhaps those additional four years of education would have given her the springboard to support one or more of her kids in going to college.
It’s very clear to me, having this reality just two generations behind me, that opportunity for success is not something easily accessible to everyone. So often, it requires several generations of success to launch new generations up to a certain level of affluence. Even if there is a chance to make disruptive change from poverty, in circumstances where resources are scarce there’s a strong encouragement to take care of others (like my grandmother did) rather than oneself. Or to achieve less success than you could find for yourself, by bringing up others with you along the way.
This is why I have to laugh when I hear people talking about how in America you can go as far as you want to go. Yes, it’s true that here there is the freedom as an individual to make great progress, more so than in any other country, but there’s a cost to it. Not everyone is willing to leave behind responsibilities to support family members needing help. It’s much easier for some than others to have that single-minded focus on success. You have to be able to afford it, in terms of money and social norms. In a way, it’s about being able to afford being selfish. That’s what we aspire to, as Americans. (Is this a good thing?)
I often wonder why people in my demographic buy luxury cars (even if used) for their teenagers and don’t ever expect them to get jobs. Is success as easy as simply wanting it? Are we raising a generation that doesn’t know how to work hard, just to be able to drive a beater car? Or even–gasp–pay for gas to drive the parents’ car?
Not everyone in the “upwardly mobile” set in America is (a) selfless enough or (b) self-sufficient enough to be able to truly make it on their own. Even when upper middle-class kids work in high school and college, typically it’s to pay for extras (going out) and not to contribute to the overall resources of a larger family. Their families pay for their tuition, food, clothing and other necessities, keeping them from truly knowing what it means to sacrifice and make their own way.
So when I read stories like this one, from the thoughtful Atlantic (September 2011 issue), I wonder what level of education my kids will have to attain in order to be successful. Is the middle class truly doomed? That’s a lot of people, just like my own family. It’s interesting to see how distanced we’re becoming from the upper class in terms of earning power, despite higher education.
And, I wonder, will this next generation define success in other terms, not related to money or affluence, but instead related to happiness and personal/community fulfillment? Was the platform that my grandmother created for me destined to help a new generation to hit the reset button on what it means to “go far?” Will hitting an economic flat-line have a more positive effect on our overall well-being?
In my years working at PR agencies, I had no better training than the time I got personal coaching by local news anchor Angela Pace. She’s a legend in the Columbus, Ohio area. Even my dad knows who she is.
(Side note: She went to South HS, as did my parents, and my dad insisted that I say, “Go Bulldogs!” when I met her. Which I did. But that’s another story.)
My boss decided that a colleague and I needed help with our new business presenting skills. She was right. To be fair, presenting for new business is one of the toughest things that you can do. Those who’ve done it will understand. Those who have not probably won’t.
They say that you cannot teach an old dog new tricks. Evidently, I am not yet an old dog, because I did learn some new tricks from Ms. Pace. I’m a decent public speaker, but under her tutelage, I kicked it up a notch. And laughed a lot, including at myself, in the process.
Here’s what I learned:
Probably the biggest thing that I learned was not to take myself too seriously.
Smile more.
Don’t assume that people want to dwell on all of those details.
Smile again.
Don’t forget to bring your water.
Warm up beforehand.
And don’t forget to breathe.
Then smile (yes, again). It’s true: The smiling is really not easy for a serious person like me. I have got to learn to be less serious!
I feel very lucky to have experienced this individualized training. Most public speaking trainers apply a formulaic approach, but not so with Ms. Pace. She paid attention to every non-verbal, every nuance of what I said and how I said it. She was not shy to stop me mid-stream and make me start again. There was no escaping her. She noticed every detail. This was a good and bad thing!
If you are in a career where public speaking, in small or large groups, is important, I’d highly recommend working with a coach who cares, knows the ropes and forces you to get outside the podium. It forced me to think differently about how I interface with people in my presentations–and it made a big difference in the end results.
Fair warning: This post may offend some people. But I’ve been thinking about writing it for a while, so here goes.
Tonight I saw a Facebook post by a friend about a model named Janice Dickinson. Apparently, she is the (in her words) “first-ever supermodel.” I didn’t remember her from her modeling days in the 80s, but I recognize her because she’s one of the judges on the show “America’s Next Top Model.”
The reason I remember her is that she is downright scary-looking. Her face is so stretched out, she looks like The Joker. The effect on her mouth is like a wide-mouth bass’s grin. Yikes.
Wondering what she looked like before plastic surgery, I took a peek at the interwebs. And wow, I can see why she was the first-ever supermodel. She was really beautiful.
And here’s the thing: I think she still would be now, if she hadn’t had so much plastic surgery. I am 100% confident that she would still be stunning, however old she is. I wish she felt that way, too.
Plastic surgery is interesting to me. I know a lot of people who’ve done it, or who’ve had Botox treatments. To each his or her own, I say. If it makes you happy and you’re not hurting anyone, then so be it. My feelings about it have more to do with just not understanding the motivation than judging people for deciding they need to do it.
This is what it seems like, to me:
When women reach “a certain age” (I can say this because I’m pretty sure that being 43, I am right there), they want to get their youth back. And they will do all sorts of things to change their bodies, to feel and look young again. The other thing that’s so common now is that that I see women at my age getting too thin. And then they lose too much weight and end up looking like skeletons. I think that you lose some personal integrity–a small part of your dignity–when you do this. Similar to being in a relationship with someone much younger. It’s just out of balance.
Going overboard with the plastic surgery or getting too thin actually makes women look older, I think. It makes that desire to be young again more obvious, and sad in a way. It seems desperate to me, going backward instead of forward. Kind of like being on a treadmill and slowly losing pace, until you ultimately fall off the back.
I just can’t imagine wanting to go backwards in time. Maybe it’s the way I’m wired: I always think that the future will bring good things. I have no desire to go back to my teens, 20s or 30s. Maybe I’ll feel differently when I hit 50. I’ll report back then.
Plastic doesn’t bring back being young. Why not just get a haircut and an extra ear piercing? |
Is electrophoretic mobility determination meaningful for aluminum(III) coagulation of kaolinite suspension?
It is commonly believed that zero suspension electrophoretic mobility (EM) caused by proper aluminum (III) [Al(III)] addition is important for an effective Al(III) coagulation process. Electrostatically stabilized particles with either highly negative or highly positive EM are conventionally believed to be difficult to aggregate with one other because of strong repulsive forces. However, it was observed that an effective Al(III)-coagulation process evaluated by both floc growth rate and particle removal efficiency can be achieved in some cases of highly positive EM or highly negative EM. Similar EM values did not guarantee similar coagulation performance, and different EM values were accompanied by quite parallel coagulation performances in some cases. The results indicate that unlike charge neutralization, enmeshment of particles by voluminous flocs was independent of the EM of particles. Although EM was reversed in sign or was close to zero, the coagulation rate was very slow without flocs, making the particle removal efficiency low. On the other hand, solution pH and Al(III) concentration were found to strongly affect coagulation efficiency. |
Statement of the National Writers Union
On August 5, 1995, before Congress passed the unconstitutional Communications Decency Act, the Delegates of the National Writers Union - without a dissenting vote - passed a resolution supporting free speech and privacy in cyberspace. We stated that:
We oppose any and all federal, state, or local legislation that
restricts or penalizes the content of communication among consenting parties...Electronic communication should have no less protection than print or any other form of speech.
We assert that censoring information about sexuality both violates the right to free expression and exacerbates serious social problems, such as AIDS and other sexually transmitted diseases, unwanted teen pregnancies, misogyny, and prejudice against sexual minorities.
We affirm the free-expression rights of minors, including their right to obtain information about sex and sexual identity. We also recognize the rights of parents and legal guardians to limit information access by their children, especially when those children are very young. Parents and children should decide among themselves what literature, art, entertainment, or information is appropriate without state or third-party intervention.
We assert that internet-access and online- service providers that do not censor their subscribers' posts should be treated as common carriers free of liability if illegal material is transmitted via their systems.
By our constitution, "The National Writers Union is committed to freedom of the press, freedom of speech, and freedom of expression in all media, including print, film, and electronic media of any sort." Among writers organizations, we were the first to recognize the power and promise of electronic communication.
For the first time in history a truly free marketplace of ideas is possible. Such freedom poses a threat to existing power strongholds - oppressive governments and the international corporations that control print and broadcast media. We are not surprised that every government in the world, including our own, strives to limit what we can say in cyberspace.
Fortunately, as Americans we have the protection of the First Amendment, and have recourse when elected officials infringe fundamental inalienable rights. The National Writers Union is proud to be a plaintiff in this historic suit to preserve our freedom.
The National Writers Union represents 4,500 freelance writers nationwide. We are journalists, book authors, poets, writers of short fiction, business and technical writers, academics, cartoonists, and workers in all genres. Our membership comprises some of the most distinguished names in American letters. We abhor the abuse of both state and corporate power to crush freedom of expression. |
An NFL Players Association spokesman said he is hopeful the players union will be able to bargain toward a better marijuana policy than one which even a team owner believes is outdated and wants to change.
Pro Football Talk reports that despite a push from Cowboys owner Jerry Jones to reconsider the league’s outdated marijuana policy, the league “isn’t likely to do it unilaterally because the issue resides squarely in the gears of collective bargaining.” And while NFLPA spokesman George Atallah said it’s “encouraging to see someone from management who’s interested in a more progressive viewpoint,” referring to Jones’ statement, he is not fooling himself into thinking gaining ground on marijuana will be an easy task.
“This is clearly one that falls into that health-and-safety space. We know exactly how players feel after the games, what their career are like, and what their lives are like after they’re done playing football,” Atallah said during Pro Football Talk’s weekly live chat. “It’s incumbent upon all of us to take the hard look and see how we can help players. And it’s a little bit challenging to feel like the only entity who cares about these players as human beings, as men, as family men, when they’re facing health and safety issues,” he said.
Compounding the importance of changing the league’s policy on medical marijuana is a recent survey by Bud Trader, that polled 152 current NFL players on a variety of topics related to prescription drug use and pain. The results showed players overwhelmingly use highly-addictive opioid-based painkillers to recover from injuries. Many say they had felt pressure by team personnel to take the pills and also that they had at some point either become addicted to the painkillers and/or believed that a teammate had been. |
I have some homesite lots in Los Barriles, Mexico in Baja near Cabo San Lucas. These are beautiful ½ acre Ocean View lots just a block or 2 from the Sea of Cortez. I am looking to trade one for a house or other income property in Las Vegas. The trade can be all or partial or cash sale or carry. I prefer a good area. You can see them at our website www.bajadreamviewestates.com. There is a total of 18 legally subdivided gorgeous view homesites and each homesite has its own parcel number. These lots were worth close to $200,000 each a few years ago and of course prices have changed now but the area is highly desirable. The biggest growth that will occur in Baja is in that area and soon. Los Barriles is a small town 45 minutes from Cabo San Lucas which has everything there including Costco, Home Depot, SuperWalmart etc. etc.The area is extremely safe and many people are retiring down there. Did I mention the best fishing in the world as well as Golf. You can either call me at 818-3325660 or toll free 866-288-0033 or reply here.
lasvegas.backpage.com is an interactive computer service that enables access by multiple users and should not be treated as the publisher or speaker of any information provided by another information content provider. |
Sandy Wexler is about a WWE fighter who ultimately realizes that the WWE is a scripted show and thus he can never get ahead. Sandy Wexler is played by Adam Sandler and the WWE fighter is played by none other than Terry Crews
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Thursday, September 3, 2015
Blood Splattered Blu: Nightmare Castle (1965)
Shes worked with Fellini, Corman Cronenberg and so many others. The pale skinned beauty with fiery seductive eye cheek bones that could kill, Barbara Steele rose from a time when men dominated the horror landscape. With hard work and talent she has rightly taken her place among horror icons like Price, Cushing, Lee etc.To honor her legacy of terror Severin has released not one but three classic Barbara Steele movies on blu. But how do they stack up and are they worth adding to your haunted collection?
The Film: I had never seen "Nightmare Castle prior to this release so I wasn't quiet sure what to expect. Even with lots of plot holes and some needlessly long scenes, it still manages to be campy fun. Its also really helped by some beautiful cinematography, great surreal moments and violence ahead of its time. It also boosts a score by the legendary Ennio Morricone who of course would go on to do great work for Sergio Leone and Serigo Corbucci Dario Argento among others. Non fans of this type of horror might not be into this but fans of classic Gothic horror will find this a tasty treat, flaws and all.
Picture: Nightmare Castle is presented in a 1080p HD res. I was totally blown away by how great Nightmare Castle looks. At fifty years old this year I can say its probably never looked better. I`m not sure but i`d go out on a limb and say this was a 2k scan from the negatives. Its stunning. There are a few flaws later in the movie but I have a feeling it was something that couldn't help. It really doesn't detract or take away anything. Severin out did themselves in terms of picture.
Extras: A nice featurette "Barbara Steele In Conversation" is a great 30 minute over view of Steele talking about her very interesting film career. Its very candid and she has some wonderful stories to tell. The crown jewel in the features is the commentary with Barbara Steele and David Del Valle. It is wildly entertaining. Del Valle is armed with wit,fun trivia and well researched facts and you can tell they are having a good time recording it. There are also a some cool features for Castle of Blood and Terror Creatures from the Grave. We have deleted scenes from Terror Creature and a featurette "Vengeance from Beyond" and "A Dance of Ghosts" featurette. Rounding out the features are trailers for all three films as well as US and UK trailer for Nightmare Castle. I was most impressed that they included features for the other two films as well, which shows just how they went above and beyond for fright fans.
Overall: Severin has really out did themselves with this release. We get treated to not one but THREE great films starring the dark diva looking beautiful in HD, along with a host of great new features including rare insights by Ms.Steele herself in both interview and commentary form. But they dont stop there, they include several features for the bonus films as well. I would put this on my short list for best blu release of 2015. A highly recommend bringing these classics into your haunted castle and adding them to your film library. |
1. Field of the Invention
The present invention generally relates to a noise removing apparatus in an FM receiver. More particularly, the present invention relates to an improved noise removing apparatus for removing a multipath noise utilizing a prior pulsive noise removing circuit.
2. Description of the Prior Art
FIG. 1 is a block diagram showing an example of a prior art noise removing apparatus in an FM receiver where the present invention can be advantageously employed. The example as shown in FIG. 1 shows an FM stereo receiver. The FM stereo receiver comprises an antenna 1 for receiving a broadcast FM signal wave, a high frequency amplifier 3 for amplifying the FM signal received by the antenna 1, a local oscillator 7 for generating a local oscillation signal for the purpose of frequency conversion, a mixer 5 for mixing the amplified FM signal from the high frequency amplifier 3 with the local oscillation signal for converting the frequency of the FM signal into an intermediate frequency, an intermediate frequency amplifier 9 for amplifying the intermediate frequency signal from the mixer 5 and an FM detector 11 for demodulating the intermediate frequency signal into the original low frequency signal. The low frequency signal from the FM detector 11 is applied to a stereo multiplex circuit 19 through a delay circuit 13, a gate 15 and a store/pilot signal generating circuit 17. The stereo multiplex circuit 19 demodulates the provided low frequency signal into the original stereo signal. The left and right low frequency signals from the stereo multiplex circuit 19 are applied to left and right loud speakers 25 and 27, respectively, through a left low frequency amplifier 21 and a right low frequency amplifier 23. Detailed structure and operation of the respective blocks are well known to those skilled in the art. Hence, it is not believed necessary to describe the same here in more detail.
Circuits 13, 15 and 17 are interposed between the FM detector 11 and the stereo multiplex circuit 19 for removing a noise. The delay circuit 13 delays, say for 3 to 5 microseconds the low frequency signal from the FM detector 11 to provide the delayed signal to the gate 15. The gate 15 is interrupted when a pulsive noise is detected by a pulsive noise detecting circuit 31 as described subsequently and prevents the pulsive noise from being transmitted to the subsequent stage. The store/pilot signal generating circuit 17 is of a circuit for preventing a stereo pilot signal from being disturbed by opening or closing the gate 15. Such store/pilot signal generating circuit is typically seen in U.S. Pat. No. 4,066,845, issued Jan. 3, 1978 to the same assignee as the present invention and U.S. Pat. No. 3,739,285, issued June 12, 1973.
The low frequency signal from the FM detector 11 is also applied to a high-pass filter 29. The high-pass filter 29 is designed to detect the energy of a noise component included in the output of the FM detector 11 and is adapted to pass the signal component of the frequency (however, the frequency must be higher than an SCA band, in case of an SCA broadcast) higher than the stereo composite signal. The pulsive noise detector circuit 31 is aimed to detect a pulsive noise in the output of the high-pass filter 29 and is adapted to trigger a monostable multivibrator 33 upon detection of such pulsive noise. The monostable multivibrator 33 continues to provide an output for a predetermined time period after the same is triggered, so that the gate 15 is interrupted when the output is obtained from the monostable multivibrator 33. Thus, the pulsive noise can be prevented from being sounded from the loud speakers 25 and 27.
Such pulsive noise removing apparatus is known in U.S. Pat. No. 4,278,901, issued July 14, 1981, U.S. Pat. No. 4,289,981, issued Sept. 15, 1981 and the like and thus it is not believed necessary to describe the same here in more detail. The above described U.S. Pat. Nos. 4,278,901 and 4,289,981 both are assigned to the same assignee as the present invention.
A prior art noise removing apparatus as shown in FIG. 1 improves various points and, particularly, brings about an excellent meritorious effect as far as the removal of a pulsive noise is concerned. However, no multipath noise can be considered in any of prior art apparatuses. The multipath noise means a noise caused by a phase difference between received signals including a reflective signal wave as well as a direct signal wave which are received by a receiver. In particular in an FM stereo receiver, a stereo pilot signal having a frequency of 19 kHz mainly generates a large noise component, as shown in FIG. 2, due to an adverse effect of the multipath. The noise caused from the pilot signal basically comprises a repetition of 19 kHz and generates an audible noise from a loud speaker when the noise is demodulated. Such multipath noise is frequently generated in case where a receiving point where an FM signal is received by an FM receiver is continuously changed, for example, in case where the FM receiver is loaded in a car, and thus such multipath noise must be fully considered in a so-called car stereo. |
Solid lipid extrusion with small die diameters--electrostatic charging, taste masking and continuous production.
The aim of this work was to develop a continuous solid lipid extrusion process that includes post-process milling of the extrudates. Die diameters smaller than 0.5 mm should be used for taste masking of the bitter tasting anthelmintic praziquantel. During lipid extrusion with small die diameters, electrostatic charging of the extrudates occurred. This could be avoided by adding liquid polyethylene glycol (PEG) as antistatic agent. Further, extrusion with PEG as antistatic agent was possible with small diameter down to 0.2 mm and with up to 80% praziquantel load. Dissolution of praziquantel extrudates was shown to be faster with smaller extrudate diameter due to surface enlargement. Anyhow, different praziquantel extrudates with small diameter, drug load up to 70% and PEG content up to 20%, were proven to be sufficiently taste masked in a randomised palatability study with 40 cats. Within a scale-up experiment, lipid extrusion and milling of the extrudates in a centrifugal mill afterwards were conducted continuously. Extrudates from continuous and batchwise production revealed small differences in terms of size distribution and surface habit, but were similar in drug dissolution rate. |
ASAP
OSHA Joins the SEC in Attacking Confidentiality and Other Provisions in Private Settlement Agreements
By Ed Ellis, Chip Jones and Kevin Griffith on
September 19, 2016
On September 15, 2016, the federal Occupational Safety and Health Administration (OSHA) released new policy guidelines for its review of private settlement agreements presented to the agency for approval in whistleblowing actions.1 OSHA issued these guidelines based on its concern that certain confidentiality and other provisions in settlement agreements may unlawfully restrict or discourage employee activity that the government would like to protect and promote.
The OSHA guidelines extend the approach recently adopted by the U.S. Securities and Exchange Commission (SEC). As discussed in our prior Insight,2 the SEC issued an agreed cease-and-desist order on August 10, 2016 in BlueLinx Holdings, Inc., requiring the company to amend its severance agreements. In that cease-and-desist order, the SEC directed the company to remove language from its agreements that prevented employees from accepting monetary awards from the SEC for whistleblowing complaints. BlueLinx also agreed to pay a $265,000 civil penalty.
The OSHA guidelines introduce additional criteria that the agency will consider when evaluating whistleblower settlement agreements. These criteria are consistent with the SEC's rationale in BlueLinx Holdings, Inc. The guidelines also extrapolate OSHA’s existing proscription on “gag” provisions, which prohibit, restrict, or discourage employees from participating in protected activity.3
Indeed, OSHA has now put employers on notice that it will reject settlement agreements that include the following types of language:
Any restriction on the complainant’s ability to assist the government. For example, the agency will not permit any agreement to restrict an employee’s right to inform the government about an occupational injury or other exposure.
Any requirement that the complainant notify the employer before contacting the government to file a complaint or otherwise discuss the employer’s prior, ongoing or future conduct. Also prohibited is a requirement that an employee “affirm that he or she has not previously provided information to the government or engaged in other protected activity, or to disclaim any knowledge that the employer has violated the law.” According to OSHA, such a limitation would discourage employees from coming forward and would therefore “compromise statutory and regulatory mechanisms.” Presumably, asking the employee to notify the employer after-the-fact—and on an entirely voluntary basis just so the employer knows that an injury or exposure has occurred—may not be prohibited. But, OSHA’s guidelines are silent on this possible language.
Any requirement that the complainant waive his or her right to receive the full amount of any monetary award (e.g., a reward) from the government for providing information to the government. OSHA thus will not approve any agreement in which the employee must waive his or her right to an award from the SEC or must give any part of that award back to the employer.
OSHA also expressed its concern about settlements that provide for liquidated damages to be paid by a breaching party. Although the agency did not explicitly ban that practice, it may exercise its discretion to reject such settlements “where the liquidated damages are clearly disproportionate to the anticipated loss” to the employer from any breach.4 Liquidated damages provisions are most commonly associated with employee breaches of confidentiality provisions in settlement and severance agreements regarding the agreement’s payment terms, and breaches of restrictive covenants such as non-competes, non-solicits and non-recruitment restrictions.
In addition, OSHA set out language it may request the parties include where a particular agreement violates the new guidelines. In that event, OSHA may ask the parties not only to remove the offending terms but also to add:
Nothing in this Agreement is intended to or shall prevent, impede or interfere with complainant’s non-waivable right, without prior notice to Respondent, to provide information to the government, participate in investigations, file a complaint, testify in proceedings regarding Respondent’s past or future conduct, or engage in any future activities protected under the whistleblower statutes administered by OSHA, or to receive and fully retain a monetary award from a government-administered whistleblower award program for providing information directly to a government agency.
Finally, because OSHA enforces more than 20 federal whistleblowing statutes—including the Sarbanes-Oxley Act—these new guidelines have a broader reach than the SEC’s earlier action since OSHA governs employers who are not publicly traded companies. As a result, even employers who are not regulated by the SEC should now review their severance, settlement, and confidentiality agreement templates, to ensure compliance with OSHA’s new guidelines.
Information contained in this publication is intended for informational purposes only and does not constitute legal advice or opinion, nor is it a substitute for the professional judgment of an attorney. |
Mallett scheduled to visit Titans next month
Arkansas quarterback Ryan Mallett is one of the more intriguing players available in the upcoming NFL Draft. The Titans are preparing to take a closer look.
Mallett is scheduled for a pre-draft visit to Baptist Sports Park on April 12-13. The Titans sent quarterbacks coach Dowell Loggains and scouting director Blake Beddingfield to Mallett’s pro day earlier this month.
The Titans are expected to bring in all the top quarterback prospects at some point before the April 28-30 draft. The team has been sending representatives to pro days this month as well. |
Long-term double-blind evaluation of amlodipine and nadolol in patients with stable exertional angina pectoris. The Investigators of Study 152.
The efficacy and tolerability of amlodipine 2.5-10 mg once daily was compared with nadolol 40-160 mg once daily in a long-term double-blind parallel-group study in patients with stable exertional angina pectoris. A total of 80 patients were randomized to receive amlodipine or nadolol for 26 weeks after a 2-week single-blind placebo run-in period. The effects of amlodipine and nadolol on total exercise time were minimal and not significantly different. However, amlodipine produced a slightly but not significantly greater increase in time to onset of angina than nadolol (+21% amlodipine; +8% nadolol). No significant differences were noted between amlodipine and nadolol on ST-segment depression, angina attack rate, or nitroglycerin consumption. A slightly greater improvement was attained after amlodipine on patient and investigator assessments of treatments. A statistically significant difference (p < 0.0001) was found between treatments on the effects on myocardial oxygen requirements (as assessed by the rate pressure product). Nadolol produced a reduction of 29% compared with a slight reduction of 4% with amlodipine. Fewer side effects were reported with amlodipine (43%) than with nadolol (83%) (p < 0.0001), resulting in discontinuation of therapy in three amlodipine and four nadolol patients. Long-term treatment with amlodipine and nadolol produced comparable effects in patients with angina pectoris, with fewer side effects being reported after treatment with amlodipine. |
Q:
What happens if I pay for changing my character appearance but end up canceling the editing?
On the New Generation versions of Grand Theft Auto Online, you can pay GTA$100.000 for editing your character appearance from the interaction menu.
What happens if I go back to the game without doing any changes? Is my money refunded?
A:
TL;DR: The money is taken after you make the character changes. If you don't make any changes, no money will be charged.
So, I picked up the "Change Appearance" option from the interaction to see what would happen:
That threw me into the character editor:
On that screen, I just pressed circle to go back into the game and it told me that no charge was made:
After confirming that, the game sent me into the Single Player mode. After going back to GTA Online, I checked if my GTA$100.000 were still there and they were:
|
/*********************************************************
* author：Gavin
* created：2017-8-9
* copyright：Copyright © 2016-2017 Stepon Technology CO.,LTD
*********************************************************/
using System.Drawing;
using Stepon.FaceRecognizationCore.Common;
namespace Stepon.FaceRecognizationCore.Extensions
{
public static class RectangleExtensions
{
/// <summary>
/// 将MRECT转换为Rectangle
/// </summary>
/// <param name="self"></param>
/// <returns></returns>
public static Rectangle ToRectangle(this FaceRect self)
{
return new Rectangle(self.left, self.top, self.right - self.left, self.bottom - self.top);
}
}
} |
150’ on the river – 1 acre+ Wide riverfront property in the desired Town of Sewall’s Point in Stuart, FL. High on a bluff with panoramic views and relaxing sunsets! Bring your ideas and build the home of your dreams. Enjoy the easy going lifestyle of Stuart, FL with downtown shopping and dining, lots of pet friendly parks, miles of beautiful beaches and nature preserves, private airport, museums, and so much more! |
Q:
SystemIdleMode.KEEP_AWAKE not Working in desktop Application
i am developing desktop application in Adobe AIR, Now i am on windows, it has setting to turn off display. i set it to 1 min. it working well. but i want to turn off the display when my application is not running. i searched, and i got some result which all telling me that set NativeApplication.nativeApplication.systemIdleMode = SystemIdleMode.KEEP_AWAKE; in you application and you achived what you want. all searched result say that when you set systemIdleMode to KEEP_AWAKE and display didn't off till your application is running.
i set this setting in initialize event of Application.
Referenace:
http://help.adobe.com/en_US/FlashPlatform/reference/actionscript/3/flash/desktop/SystemIdleMode.html
i think, May be some usage issue in it, nothing more in it, please help me !!!
A:
From adobe AS3 docs:
AIR profile support: This feature is supported on mobile devices, but it is not supported on desktop operating systems or AIR for TV devices. See AIR Profile Support for more information regarding API support across multiple profiles.
The important part is highlighted with bold text.
Hope it helps!
|
Translocation by multi-subunit RNA polymerases.
DNA template and RNA/DNA hybrid movement through RNA polymerase (RNAP) is referred to as "translocation". Because nucleic acid movement is coupled to NTP loading, pyrophosphate release, and conformational changes, the precise ordering of events during bond addition is consequential. Moreover, based on several lines of experimental evidence, translocation, pyrophosphate release or an associated conformational change may determine the transcription elongation rate. In this review we discuss various models of translocation, the data supporting the hypothesis that translocation rate determines transcription elongation rate and also data that may be inconsistent with this point of view. A model of the nucleotide addition cycle accommodating available experimental data is proposed. On the basis of this model, the molecular mechanisms regulating translocation and potential routes for NTP entry are discussed. |
Craniofacial hyperhidrosis treated with video endoscopic sympathectomy.
Craniofacial hyperhidrosis as well as palmar hyperhidrosis is an abnormal state of local excessive sweating of unclear etiology. The hyperhidrosis may be isolated in the craniofacial region or associated with palmar hyperhidrosis. The patient's face is so wet with sweat that their daily activities are often seriously disturbed. To the best of our knowledge, there has been no satisfactory medical therapy, nor any effective surgical treatment reported in the literature. In 1991, we started to treat a patient with such distress using endoscopic ablation of the sympathetic T2 segment, because we mastered the technique after treating a large series of palmar hyperhidrosis patients. Furthermore, we were impressed by concomitant reduction of craniofacial sweating after T2-3 sympathectomy resulting from the relatively different domination of sympathetic supply between the eye and face. It appears possible to relieve excessive sweating of the head and face, without producing ptosis or miosis by ablation of the T2 segment. During the past 2 years, 7 patients with severe craniofacial hyperhidrosis have been successfully treated with the method and all obtained a satisfactory result. No complete Horner's syndrome has been produced except in one patient, who showed a mild and transient left eye ptosis, in whom coagulation of the sympathetic trunk higher than the T2 segment was performed. Intraoperative monitoring of forehead skin perfusion and observation of the change of pupillary size is emphasized during the lesion making. The longest postoperative follow-up was 2 years, with a mean follow-up of 12.4 months.(ABSTRACT TRUNCATED AT 250 WORDS) |
Fractional charged edge states in ladder topological insulators.
We propose a model of two-leg ladder topological insulator in which the spin-orbit couplings are presented in both intra-chain and inter-chain interactions. The topological phase supports four fractional charged edge states localized at opposite ends of the ladder, which belongs to the chiral symplectic (CII) class protected by time-reversal symmetry and chiral symmetry. In our model, the presence of time-reversal and chiral symmetry generates fourfold degeneracy for the edge states, and the two edge states with same chirality at one end of the ladder each carries half charge. In contrast to the two edge states spatially localized at one end of the ladder being not distinguished, these two edge states can be detected by the momentum density. The experimental scheme for realizing our model with cold atoms in optical lattice is discussed. By introducing a magnetic field in the x direction, the system is driven from CII class to AIII class. In AIII class, there exist two distinct topological phases that exhibit four degenerate edge states and two degenerate edge states in the gap, respectively. As same as the system in CII class, each edge state carries a half charge in AIII class. |
Multiphase chemistry of glyoxal: revised kinetics of the alkyl radical reaction with molecular oxygen and the reaction of glyoxal with OH, NO3, and SO4- in aqueous solution.
The rate constant for the reaction of the hydrated glyoxyl radical (CH(OH)2-C(OH)2(·) with O2 has been determined as k(298) K = (1.2 ± 0.3) × 10(9) L mol(-1) s(-1) at pH 4.8. This experimental value is considerably higher than a widely used estimated value of about k = 1 × 10(6) L mol(-1) s(-1). As the aqueous phase conversion of glyoxal is of wide interest for aqSOA formation, we suggest that the newly determined rate constant should be applied in multiphase models. The formation of the dimerization product tartaric acid has as well been studied. This product is found, however in significant yields only when the oxygen content of the solution is reduced. The formation of dimers from the recombination of alkyl radicals in the atmospheric aqueous phase should hence be treated with great care. Finally, the reactions of the free radicals OH, NO3, and SO4(-) with glyoxal have been investigated and rate constants of k(298) K (OH) = (9.2 ± 0.5) × 10(8) L mol(-1) s(-1), k(298) K (SO4(-)) = (2.4 ± 0.2) × 10(7) L mol(-1) s(-1) and k(298) K (NO3) = (4.5 ± 0.3) × 10(6) L mol(-1) s(-1) were obtained. |
My partner and I are arguing about whether screens cause problem behaviour in kids or not. I say they do but he says they don’t. Our 9 year-old wants a TV in his room to play video games on. I’m saying no. Am I right? My partner thinks it’s fine and will keep him out of our hair. Am I being too “precious” which is what my partner is saying?
The short answer is… “You’re right. He’s wrong.”
Let me explain why your partner needs to back down and listen to you.
When it comes to technology, having screens in bedrooms is one of the most well-established risk factors for our children’s positive development. This is for two central reasons:
1. When a screen is in the bedroom, the simple fact is that parents have no idea what their kids are watching. (This is called the “content” hypothesis.)
2. Parents have no idea how much they’re watching. (This is called the “displacement” hypothesis because screens displace more important activities.)
Do you know what they’re watching?
In relation to content, a recent study published in the prestigious Developmental Psychology journal highlighted that children with bedroom media are likely to be exposed to more media violence than those without screens in their room. This led to kids’ feeling that violence and aggression are ok, and they behaved more aggressively than their peers.
Other research shows that kids become more hostile in relationships because of screen media, and they see other content that is harmful to their wellbeing, including pornography.
The reality is that they’ll see concerning content whether they have a screen in their room or not. But one thing is for sure… they’re definitely going to watch more screens and increase their risks when they have them in their room. Evidence from the Longitudinal Study of Australian Children highlights that as soon as kids have screens in their room, they stare at them longer. The latest research shows that about 25% of Aussie children aged 6-11 years had a TV in their bedroom in 2015. At age 12-13 years, the number of kids who could watch TV in the bedroom rose to around 50%, including laptop or other screen access. Data from around the world shows that the percentages only increase as children get older.
Are they streaming or dreaming?
It’s not just about what they watch that affects their development. It’s what screens replace that matters too! During the day, they miss out on relationships, exercise, extra-curricular activities, and down time. At night, tather than dreaming, kids are streaming – or gaming – and it impacts their wellbeing in significant ways.
Australian data indicates screen time is affecting obesity, physical activity, and other social outcomes. If kids are too tired, they don’t relate well to others. And there is strong evidence that screens are impacting children’s behaviour, and their academic results. Plus, research shows that kids go to bed later, sleep less, and experience lower quality sleep when a screen is in their room.
Dealing with opposition
Now that we’ve got the evidence out of the way, it’s important that you don’t wave this article in your partner’s face and say, “Told you so. Ner ner ner ner ner.” We need to have more mature ways of communicating about these things.
I’d suggest the following:
First, ask him why it’s such a big deal to him that your son has a TV in his room. Be polite and genuinely try to understand. Perhaps he has some strong reasons. Or maybe he was allowed one as a child and thinks it didn’t affect him negatively. Listen and understand.
Second, ask him what outcomes you both want for your son and discuss how a TV may or may not help to achieve those outcomes.
Third, describe your concerns to him. Ask if he can listen without judgement so that he can really get what you’re saying.
Finally, focus on “where to from here”, so that you can problem-solve together. It’s important that you are united before you start conversations with your son about this. Don’t bully one another though. Remember the couplet:
One convinced against their will Is of the same opinion still.
Whether it’s messing with their brain, impacting their relationships, affecting their physical health, or leading to depression, there are no strong reasons to put a screen into your child’s bedroom.
And keep this in mind: it’s much easier to never allow media in the bedroom than to allow it and then try to take it back out. The answer comes down to one simple word – just two letters – that can be tough to say. But that little word can save a LOT of pain down the track.
About the Author: A sought after public speaker and author, and former radio broadcaster, Justin has a psychology degree from the University of Queensland and a PhD in psychology from the University of Wollongong. |
Ovl
News for Ovl
The firm has now proposed two options -- either Venezuela offers it crude oil in lieu of the dues or adjustments are made with 300,000 to 400,000 barrels per day of crude oil being imported by RIL.......
In the third acquisition in 10 months, state-owned Oil and Natural Gas Corp (ONGC) and Oil India Ltd (OIL) will buy Videocon Industries' 10 per cent stake in a giant Mozambique gas field for about......
ONGC Videsh Ltd and Oil India Ltd will buy Videocon Industries' 10 per cent stake in a giant Mozambique gas field for $2.475 billion. The acquisition of the stake in Mozambique's offshore Area 1,...... |
A Wet Wool Felting Party
Posted by Natasha McCrary on Apr 13, 2013
Recently, friend of the farm, Ava Bryant, celebrated a birthday with 11 of her best friends. They had a wonderful time at the farm meeting the friendly animals, gathering eggs, and making a wet wool felting craft from dyed sheep’s wool in the Garden House. They were very patient as they rolled and rolled the wet wool into hard felt balls to make their beautiful and unique necklaces. |
Q:
Calling same method from two different class
public boolean createPricebreakupOrder(int x, int y) {
boolean returnFlag = false;
try {
if (x == y) {
returnFlag = true;
}
} catch (final Exception e) {
LOG.debug("Exception while Price Breakup Create" + e.getMessage());
returnFlag = false;
}
return returnFlag;
}
Now I am calling this method from two different classes; and passing the same parameter in, from each class. For the first class, the method is getting executed and returnFlag = true. While for other, even with the same parameters, it is returning false.
A:
Be assured that because the code in the try block does not ever throw an exception, your function is equivalent to
public boolean createPricebreakupOrder(int x, int y)
{
return x == y;
}
There is nothing non-deterministic about this function: the same input parameters will yield the same result.
If x and y were actually Integer types then it's possible that == will fail due to reference comparisons or, perhaps, an NPE is thrown when auto-unboxing a null Integer to an int when the function is called.
|
/*******************************************************************************
* Copyright (c) 2016 QNX Software Systems and others.
*
* This program and the accompanying materials
* are made available under the terms of the Eclipse Public License 2.0
* which accompanies this distribution, and is available at
* https://www.eclipse.org/legal/epl-2.0/
*
* SPDX-License-Identifier: EPL-2.0
*
* Contributors:
* Alena Laskavaia (QNX)- Initial API and implementation
*******************************************************************************/
package org.eclipse.cdt.dsf.mi.service.breakpoint.actions;
import org.eclipse.cdt.debug.core.breakpointactions.ICLIDebugActionEnabler;
import org.eclipse.cdt.dsf.concurrent.DsfExecutor;
import org.eclipse.cdt.dsf.concurrent.DsfRunnable;
import org.eclipse.cdt.dsf.concurrent.ImmediateDataRequestMonitor;
import org.eclipse.cdt.dsf.datamodel.DMContexts;
import org.eclipse.cdt.dsf.datamodel.IDMContext;
import org.eclipse.cdt.dsf.debug.service.command.ICommand;
import org.eclipse.cdt.dsf.debug.service.command.ICommandControlService;
import org.eclipse.cdt.dsf.debug.service.command.ICommandControlService.ICommandControlDMContext;
import org.eclipse.cdt.dsf.gdb.internal.GdbPlugin;
import org.eclipse.cdt.dsf.mi.service.command.CLIEventProcessor;
import org.eclipse.cdt.dsf.mi.service.command.commands.CLICommand;
import org.eclipse.cdt.dsf.mi.service.command.commands.MIInterpreterExecConsole;
import org.eclipse.cdt.dsf.mi.service.command.output.MIInfo;
import org.eclipse.cdt.dsf.service.DsfServicesTracker;
import org.eclipse.core.runtime.IStatus;
import org.eclipse.core.runtime.Status;
/**
*
* This class permits to execute custom user debugger commands through cli/mi bridge
*
* @since 5.0
*/
public class CLIDebugActionEnabler implements ICLIDebugActionEnabler {
private final DsfExecutor fExecutor;
private final DsfServicesTracker fServiceTracker;
private final ICommandControlDMContext fContext;
/**
* @param executor
* @param serviceTracker
* @param context
*/
public CLIDebugActionEnabler(DsfExecutor executor, DsfServicesTracker serviceTracker, IDMContext context) {
fExecutor = executor;
fServiceTracker = serviceTracker;
fContext = DMContexts.getAncestorOfType(context, ICommandControlDMContext.class);
assert fContext != null;
}
@Override
public void execute(String commandmulti) throws Exception {
String[] commands = commandmulti.split("\\r?\\n"); //$NON-NLS-1$
for (int j = 0; j < commands.length; ++j) {
String single = commands[j];
executeSingleCommand(single);
}
}
private boolean isMIOperation(String operation) {
if (operation.startsWith("-")) { //$NON-NLS-1$
return true;
}
return false;
}
private void executeSingleCommand(String str) {
// Do not use the interpreter-exec for stepping operation the UI will fall out of step.
// Also, do not use "interpreter-exec console" for MI commands.
ICommand<MIInfo> cmd;
if (!isMIOperation(str) && !CLIEventProcessor.isSteppingOperation(str)) {
cmd = new MIInterpreterExecConsole<>(fContext, str);
} else {
cmd = new CLICommand<>(fContext, str);
}
fExecutor.execute(new DsfRunnable() {
@Override
public void run() {
// TODO: for print command would be nice to redirect to gdb console
ICommandControlService commandControl = fServiceTracker.getService(ICommandControlService.class);
if (commandControl != null) {
commandControl.queueCommand(cmd, new ImmediateDataRequestMonitor<>());
} else {
// Should not happen, so log the situation but then ignore it
GdbPlugin.log(new Status(IStatus.INFO, GdbPlugin.PLUGIN_ID,
"Unable to find service to execute breakpoint command")); //$NON-NLS-1$
}
}
});
}
}
|
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