sent1 stringlengths 15 4.99k | sent2 stringlengths 14 5.05k | labels int64 0 1 |
|---|---|---|
It (beta-alanyl--histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues. It was discovered by Russian chemist Vladimir Gulevich.
It is naturally produced by the body in the liver from beta-alanine and histidine. Like carnitine, ca... | It is a natural product found in Daphnia pulex, Glycine max, and other organisms with data available. | 1 |
It is an alkaloid found in Cinchona officinalis. It is used in asymmetric synthesis in organic chemistry. It is a stereoisomer and pseudo-enantiomer of cinchonidine.
It is structurally similar to quinine, an antimalarial drug.
It is a GLP-1 receptor agonist and therefore has potential as a possible treatment for obesit... | It is a natural product found in Eremothecium ashbyi, Euglena gracilis, and Saccharomyces cerevisiae with data available. | 0 |
It is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 5,6-dimethyl-9-oxoxanthen-4-yl group. It has a role as an antineoplastic agent. It is a member of xanthones and a monocarboxylic acid. | It is a member of 1,3-oxazoles. | 0 |
It (4',7-isoflavandiol) is an isoflavandiol estrogen metabolized from daidzein, a type of isoflavone found in soybeans and other plant sources, by bacterial flora in the intestines. While endogenous estrogenic hormones such as estradiol are steroids, equol is a nonsteroidal estrogen. Only about 30–50% of people have in... | Hydroxymalonic acid is a dicarboxylic acid that is malonic acid substituted by a hydroxy group at position 2. It has a role as a plant metabolite. It is a dicarboxylic acid and a dicarboxylic fatty acid. It is functionally related to a malonic acid. It is a conjugate acid of a hydroxymalonate(1-) and a hydroxymalonate. | 0 |
It is ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the treatment of migraine and orthostatic hypotension. It has a ... | It is a fungicide, a member benzimidazole fungicides. It is a metabolite of benomyl.
The fungicide is used to control plant diseases in cereals and fruits, including citrus, bananas, strawberries, macadamia nuts, pineapples, and pomes. A 4.7% solution of carbendazim hydrochloride, sold as Eertavas, is marketed as a tr... | 0 |
It is a non-proteinogenic alpha-amino acid. | It is a sesquiterpene lactone. | 0 |
It is a trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee. It has a role as a central nervous system stimulant, an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor, an adenosine receptor antagonist, an EC 2.7.11.1 (non-s... | It is a member of the class of coumarins that is scopoletin attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It has a role as a plant metabolite. It is a monosaccharide derivative, a member of coumarins and a beta-D-glucoside. It is functionally related to a scopoletin. | 0 |
It is a member of the class of benzyl bromides that is toluene substituted on the alpha-carbon with bromine. It has a role as a lachrymator. | It is a sphingoid base, a fundamental building block of more complex sphingolipids. It is abundant in plants and fungi and present in animals. It has also been found to have interesting T-cell related anti-inflammatory properties in models of inflammatory bowel disease. | 0 |
It is a cyclic ketone that consists of cyclopentane bearing a single oxo substituent. It has a role as a Maillard reaction product. | It, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant medication which is used in the treatment of depression and for other uses. It is still available in the United States, but was withdrawn from other countries due to rare liver toxicity. The medication is ... | 0 |
Melibiose is a glycosylglucose formed by an alpha-(1->6)-linkage between D-galactose and D-glucose. It has a role as a plant metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite and an elastin-laminin receptor agonist. | It is a natural product found in Solanum lycopersicum, Coffea arabica, and other organisms with data available. | 0 |
Debrisoquin is a member of isoquinolines and a carboxamidine. It has a role as an antihypertensive agent, an adrenergic agent, a sympatholytic agent and a human metabolite. | It is a tetrabutylammonium salt with bromide as the anionic counterpart. It is an organic bromide salt and a tetrabutylammonium salt. | 0 |
It is a member of the class of bilanes that is a colourless product formed in the intestine by the reduction of bilirubin. It has a role as a human metabolite. | It is an N-arylpiperazine that is piperazine substituted by a 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl group at position 1 and by a 2,3-dichlorophenyl group at position 4. It is an antipsychotic drug used for the treatment of Schizophrenia, and other mood disorders. It has a role as a H1-receptor antagonist,... | 0 |
It is an ellagitannin with a hexahydroxydiphenoyl group bridging over the 3-O and 6-O of the glucose core. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a non-steroidal anti-inflammatory drug and an antioxidant. It is an ellagitannin and a gallate ester. | It is a sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25. A natural product found in Dioscorea (wild yam) species, it is used as the starting point for the commercial synthesis of a number of st... | 0 |
It is a psychoactive drug and research chemical which acts as a selective D and D receptor agonist. It is used in scientific research. It has been shown to increase locomotion and sniffing behavior in mice treated with it. At least one study has found that quinpirole induces compulsive behavior symptomatic of obsessive... | It is a pyrazoloquinoline that is (4aR,8aR)-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrazolo[3,4-g]quinoline substituted by a propyl group at position 5. It acts as a dopamine agonist. It has a role as a dopamine agonist. | 1 |
It is a racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction. It has a role as an opioid analgesic, a mu-opioid receptor agonist, a xenobiotic, an environmental contaminant, ... | It is an organic compound with the chemical formula (ClCH)O. It is a colourless liquid with an unpleasant suffocating odour and it is one of the chloroalkyl ethers. It was once produced on a large scale, but was found to be highly carcinogenic and thus such production has ceased. | 0 |
It is an organic sodium salt having 2-[(2-hydroxynaphthalen-1-yl)diazenyl]-5-[(4-sulfonatophenyl)diazenyl]benzene-1-sulfonate as the counterion. Used as a plasma stain in Masson's trichrome. It has a role as a histological dye. It contains a It(2-). | It is an organic molecular entity. It has a role as a metabolite. | 0 |
It is a natural product found in Lathyrus sylvestris and Phaseolus vulgaris with data available. | It is a natural product found in Fibraurea chloroleuca, Corydalis ternata, and other organisms with data available. | 0 |
It is a natural product found in Streptomyces and Tessmannia densiflora with data available. | It is a quaternary ammonium ion that is a depolarising muscle relaxant whose structure comprises a decane-1,10-diamine core in which each amino group carries three methyl substituents. It has a role as a muscle relaxant and a nicotinic acetylcholine receptor agonist. It derives from a hydride of a decane. | 0 |
It (INN), sold under the brand name Isovue among others, is a nonionic, low-osmolar iodinated contrast agent, developed by Bracco Diagnostics.
It is available in various concentrations, from 200 to 370 mgI/mL. | It is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. It is a benzenedicarboxami... | 1 |
It, sold under the brand name Daraprim among others, is a medication used with leucovorin (leucovorin is used to decrease side effects of pyrimethamine; it does not have intrinsic anti-parasitic activity) to treat the parasitic diseases toxoplasmosis and cystoisosporiasis. It is also used with dapsone as a second-line ... | It is a natural product found in Carica papaya with data available. | 0 |
It (INN), used in the form of lapatinib ditosylate (USAN) (trade names Tykerb and Tyverb marketed by Novartis) is an orally active drug for breast cancer and other solid tumours. It is a dual tyrosine kinase inhibitor which interrupts the HER2/neu and epidermal growth factor receptor (EGFR) pathways. It is used in comb... | It is an acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity. It has a role as a prodrug, a neuroprotective agent and an orphan drug. It is a member ... | 0 |
It (Operidine or Lealgin), is an opioid analgesic which is structurally related to pethidine and is used clinically as a general anesthetic. | It is a steroid ester. | 0 |
It, sold under the brand name Monurol among others, is an antibiotic primarily used to treat lower urinary tract infections. It is not indicated for kidney infections. Occasionally it is used for prostate infections. It is generally taken by mouth.
Common side effects include diarrhea, nausea, headache, and vaginal yea... | It, also known by its developmental code name R-55667, is a serotonin antagonist medication described as an anxiolytic, antidepressant, antiparkinsonian agent, and antihypertensive agent. It was chiefly investigated as a drug to treat insomnia, especially to enhance sleep quality by significantly increasing slow wave s... | 0 |
L-proline is pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-It is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of join... | It is an organic compound with the formula CHOCHCHCH=CH. It is a colorless oily liquid, although impure samples can appear yellow. A member of the phenylpropanoid family of natural products, it is found in sassafras plants, among others. Small amounts are found in a wide variety of plants, where it functions as a na... | 0 |
It is a furanocoumarin. | It is a carbamate pesticide, widely used around the world to control insects on a wide variety of field crops, including potatoes, corn and soybeans. It is a systemic insecticide, which means that the plant absorbs it through the roots, and from there the plant distributes it throughout its organs where insecticidal co... | 0 |
It is a harmala alkaloid. | It is a member of imidazolidines. | 0 |
It is a fatty acid methyl ester. | It is the organic compound with the formula (CHCHCOCH). It is a colorless oily liquid. Although the main commercial interest in adipates is related to the production of nylons, this diester is used as a plasticizer, a solvent for paint stripping and resins, and a pigment dispersant. | 1 |
It is an organosulfur compound with the chemical formula , often abbreviated as , where Ph stands for phenyl. It is a colorless liquid with an unpleasant odor. It is an aromatic sulfide. The molecule consists of two phenyl groups attached to a sulfur atom. | It is an aryl sulfide that consists of two phenyl groups connected by a sulphur atom. | 1 |
It is a natural product found in Dioscorea hispida, Dioscorea dregeana, and Dioscorea bulbifera with data available. | It is a monomethoxybenzene that is benzene substituted by a methoxy group. It has a role as a plant metabolite. | 0 |
It is a member of the class of benzazepines that is 7,8-dimethoxy-1,3,4,5-tetrahydro-3-benzazepin-2-one in which the amide hydrogen is replaced by a [{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl} group. Used (as its hydrochloride salt) to treat patients with angina who have intole... | It is a member of biphenyls and a 4-oxo monocarboxylic acid. It has a role as a non-steroidal anti-inflammatory drug. | 0 |
It is a complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile. It has a role as an antimicrobial agent, an antibacterial drug and a bacterial metabolite. It is functionally ... | It (synonyms imazalil, chloramizole) is a fungicide widely used in agriculture, particularly in the growing of citrus fruits. Trade names include Freshgard, Fungaflor, and Nuzone.
It is also used in veterinary medicine as a topical antimycotic. | 0 |
It () is a gaseous oxide of phosphorus. It is a free radical that plays a role in the chemiluminescence of phosphorus and phosphine. It is produced when phosphates are heated to high temperatures.
In the ground state the molecule is bent, like nitrogen dioxide, but there is an excited state that is linear. | It is a sulfonamide. | 0 |
Linalyl acetate is a racemate comprising equimolar amounts of (R)- and (S)-linalyl acetate. It forms a principal component of the essential oils from bergamot and lavender. It has a role as a flavouring agent, an antimicrobial agent and a food component. It contains a (R)-linalyl acetate and a (S)-linalyl acetate. | It is the sodium salt of hydrogen azide (hydrazoic acid). It has a role as a mutagen, an antibacterial agent, an explosive and a mitochondrial respiratory-chain inhibitor. It contains an azide anion. | 0 |
It, sold under the brand name Exjade & Asunra (in injectable form) & Oleptiss (Tablet formulation) both by Novartis among others, is an oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic... | It is an oxoaporphine alkaloid. It has a role as a metabolite. | 0 |
Ent-kaur-16-en-19-oic acid is an ent-kaurane diterpenoid that is ent-kauran-19-oic acid in which a double bond is present at position 16(17); exhibits anticancer and anti-HIV 1 activity. It has a role as an anti-HIV-1 agent, an antineoplastic agent and a plant metabolite. It is a conjugate acid of an ent-kaur-16-en-19-... | It is a benzamide obtained by formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary aromatic amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine. Used (as its mesylate salt) for treatment of chronic myelogenous leukemia and gastrointesti... | 0 |
It is a member of 4-pyranones. | It is a racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs. It has a role as a drug metabolite, a xenobiotic metabolite, a cholinergic antagonist, an anti-ulcer drug, a cholecystokini... | 0 |
It is a dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by ... | It is a natural product found in Camellia sinensis, Gymnodinium nagasakiense, and other organisms with data available. | 0 |
It is a natural product found in Apis cerana and Euglena gracilis with data available. | It is a natural product found in Humulus lupulus, Ficus erecta var. beecheyana, and other organisms with data available. | 0 |
It is a dialkenyl ketone. | It, or diisopropylidene acetone, is a yellow crystalline substance with a geranium odor, with formula or . | 1 |
It was a barbiturate developed in the 1920s. It has sedative and hypnotic properties, and was used for the treatment of insomnia. It was primarily sold as part of a combination product called Vesparax, composed of 150 mg secobarbital, 50 mg brallobarbital and 50 mg hydroxyzine. The long half-life of this combination of... | It is a member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens. It has a role as an apoptosis inducer, an ... | 0 |
It is a member of methoxybenzenes. | It is a monocarboxylic acid. | 0 |
It is an isothiocyanate with the formula CH2=CHCH2N=C=S. A colorless oil with boiling point 152###, it is responsible for the pungent taste of mustard, horseradish, and wasabi. It has a role as a lachrymator, a metabolite, an antimicrobial agent, an apoptosis inducer and an antineoplastic agent. It is an isothiocyanate... | It is an isoquinoline alkaloid that is the N-methyl derivative of 5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline. It is an isoquinoline alkaloid fundamental parent, an aporphine alkaloid and a tertiary amino compound. | 0 |
It is a mancude organic heterobicyclic parent and a member of indolizines. | It is an isothiocyanate that is phenyl isothiocyanate in which the hydrogen at the para- position has been replaced by a 4-nitroanilinyl group. It has a role as a schistosomicide drug. It is a C-nitro compound, an isothiocyanate and a secondary amino compound. It is functionally related to a diphenylamine. | 0 |
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline is a member of isoquinolines. | It is a natural product found in Areca catechu with data available. | 0 |
It is a member of arsonic acids. It is a conjugate acid of an arsonate(1-). | It is a carbamate ester obtained by the formal condensation of 1-naphthol with methylcarbamic acid. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a carbamate insecticide, an EC 3.1.1.8 (cholinesterase) inhibitor, an acaricide, an agrochemical and a plant growth retardant. It is a carbamate ester and ... | 0 |
It is a dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group. It has a role as a fungal metabolite and a human metabolite. It is a dicarboxylic acid, an olefinic compound and a dicarboxylic fatty acid. It is functionally related to a succinic acid. It... | It, also called freon-11, CFC-11, or R-11, is a chlorofluorocarbon (CFC). It is a colorless, faintly ethereal, and sweetish-smelling liquid that boils around room temperature. CFC-11 is a Class 1 ozone-depleting substance which allegedly damages Earth's protective stratospheric ozone layer. | 0 |
It is a natural product found in Passiflora phoenicia, Daphnia pulex, and other organisms with data available. | It, also known by the trademark Ethyl cellosolve, is a solvent used widely in commercial and industrial applications. It is a clear, colorless, nearly odorless liquid that is miscible with water, ethanol, diethyl ether, acetone, and ethyl acetate.
It is manufactured by the reaction of ethylene oxide with ethanol.
As wi... | 0 |
It is a sulfanylbenzoic acid that is the 2-sulfanyl derivative of benzoic acid. It has a role as a non-narcotic analgesic and an antipyretic. It is a conjugate acid of a thiosalicylate(1-). | It is an amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity. ... | 0 |
It (symbol Cys or C; ) is a semiessential proteinogenic amino acid with the formula . The thiol side chain in cysteine often participates in enzymatic reactions as a nucleophile. It is chiral, but interestingly, both and -cysteine are found in nature with -cysteine having been found in developing brain (see Semenza et... | It is a natural product found in Camellia sinensis, Viburnum rafinesquianum, and other organisms with data available. | 0 |
It is a nitrogen oxoacid consisting of an oxygen atom double-bonded to an NH group. | It (common name) or azanone (IUPAC name) is the chemical compound HNO. It is well known in the gas phase. It can be formed as a short-lived intermediate in the solution phase. The conjugate base, NO, nitroxide anion, is the reduced form of nitric oxide (NO) and is isoelectronic with dioxygen. The bond dissociation ener... | 1 |
It is a natural product found in Spiranthes vernalis, Phomopsis velata, and other organisms with data available. | It is a chemical compound. It is the base chemical structure of various alkaloids in the Rauvolfia and Corynanthe plant genera, including yohimbine, rauwolscine, corynanthine, ajmalicine, reserpine, deserpidine, and rescinnamine, among others. | 0 |
It is a natural product found in Taxus cuspidata, Ophioparma ventosa, and other organisms with data available. | It, also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer among others. It is given intrave... | 1 |
It is a phosphoethanolamine. | It is a natural product found in Gossypium hirsutum, Vaccinium macrocarpon, and other organisms with data available. | 0 |
It is a member of the class of isoquinolines that is (3S)-2-L-alanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid in which the alpha-amino group of the alanyl residue has been substituted by a 1-ethoxycarbonyl-4-phenylbutan-2-yl group (the all-S isomer). A prodrug for quinaprilat (by hydrolysis of the ethyl ester t... | It is a member of amphetamines. | 0 |
It is an aromatic ether. | It is a pivaloyloxymethyl ester of ampicillin. It is a prodrug, which is thought to enhance the oral bioavailability of ampicillin because of its greater lipophilicity compared to that of ampicillin.
__TOC__ | 0 |
It (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications.
While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval. It was discontinued by Wyeth in 1997 because of th... | It is an organic molecular entity. | 0 |
It is an organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties. It has a role as an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor, an angiogenesis inhibit... | (S)-colchicine is a colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions. It has a role as a mutagen, an anti-inflammatory agent and a gout suppressant.... | 0 |
It is an organic compound that is classified as lignan. It is a bioactive compound found in the bark of the Houpu magnolia (Magnolia officinalis) and in M. grandiflora. The compound exists at the level of a few percent in the bark of species of magnolia, the extracts of which have been used in traditional Chinese and J... | Leutinacin is a member of 6-aminopurines. | 0 |
It, also systematically named trihydridogallium, is an inorganic compound of gallium with the chemical formula (also written as ). It is a photosensitive, colourless gas that cannot be concentrated in pure form. It is both the simplest member of the gallanes, and the prototype of the monogallanes. It has no economic u... | It is a pentacyclic triterpenoid that is taraxastane with a beta-hydroxy group at position 3. It has a role as a metabolite and an anti-inflammatory agent. It is a pentacyclic triterpenoid and a secondary alcohol. It derives from a hydride of a taraxastane. | 0 |
It is an organic compound that is an aglycone of ginsenosides, a group of steroid glycosides. It is a dammarane-type tetracyclic triterpene sapogenin found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng). It is formed by the dehydration of protopanaxatriol. | It is a carbohydrazide and a member of pyridines. | 0 |
It is a chemical compound and an isomer of vanillin. Urolithin M7, one of the urolithins, has also been synthesized from 2-hydroxy-4-methoxybenzaldehyde using the inverse electron-demand Diels–Alder reaction. | It is a natural product found in Senegalia berlandieri and Vachellia rigidula with data available. | 0 |
It is a member of isoindoles. | It, formerly sold under the brand name Survector among others, is an atypical antidepressant of the tricyclic antidepressant (TCA) family. It acts as a selective and mixed dopamine reuptake inhibitor and releasing agent, and to a lesser extent as a norepinephrine reuptake inhibitor.
It was developed by the French Socie... | 0 |
It is an alkane hydrocarbon with the chemical formula CH. Although 75 structural isomers are possible for decane, the term usually refers to the normal-decane ("n-decane"), with the formula CH(CH)CH. All isomers, however, exhibit similar properties and little attention is paid to the composition. These isomers are f... | It is an organic compound with the formula CH(OH). It is a water-soluble, white solid although samples are typically brownish because of its sensitivity toward oxygen. It is one of three isomers of benzenetriols. | 0 |
It is a disaccharide derivative that is (S)-naringenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an anti-inflammatory agent, an antioxidant and a metabolite. It is a disaccharide derivative, a dihydroxyflavanone, a member ... | It is an aromatic ether. | 0 |
It is a 3-hydroxy steroid. It has a role as an androgen. | It is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure.
It was patented in 1982 and approved for medical use in 1990. | 0 |
It is an iridoid produced in nature by a wide variety of plants and animals. It was the first cyclopentanoid monoterpene alkaloid to be discovered. It is one of several compounds that may be extracted from the valerian (Valeriana officinalis) root and silver vine (Actinidia polygama), as well as several types of insect... | It is a member of the class of cyclopentapyridines that is 6,7-dihydrocyclopenta[c]pyridine bearing two methyl substituents at positions 4 and 7. It has a role as a plant metabolite and a pheromone. It is a cyclopentapyridine and a pyridine alkaloid. | 1 |
It is a dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group. It has a role as a human metabolite. It is functionally related to a malonic acid. It is a conjugate acid of a methylmalonate(1-). | It is a member of the class of alkylamines that is propane substituted by an amino group at C-1. It is a conjugate base of a propan-1-aminium. | 0 |
It ( , ) (systematic name methanal) is an organic compound with the chemical formula and structure , more precisely . The compound is a pungent, colourless gas that polymerises spontaneously into paraformaldehyde. It is stored as aqueous solutions (formalin), which consists mainly of the hydrate CH(OH). It is the sim... | It is a beta-carboline that is 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole which is substituted by a 3-(pyridin-3-yl)propyl group at position 2 and a fluoro group at position 8. It has a role as an antipsychotic agent and a dopamine receptor D2 antagonist. It is a member of beta-carbolines, a member of monofluorobenzenes... | 0 |
It is a member of the class of benzazepines that is 7,8-dimethoxy-1,3,4,5-tetrahydro-3-benzazepin-2-one in which the amide hydrogen is replaced by a [{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl} group. Used (as its hydrochloride salt) to treat patients with angina who have intole... | It refers to organic compounds with the formula . It occurs naturally and is classified as three-carbon sugar acid. It is chiral. Salts and esters of glyceric acid are known as glycerates. | 0 |
It is a glycoside and a lignan. | It is a bio-active isolate of the Chinese medicinal herb Zanthoxylum nitidum. It was isolated for the first time, at least with the name liriodenine, from the heartwood of Liriodendron tulipifera, the common yellow poplar of the south-eastern USA. It is found in very many other plants, notably in Annona cherimolia and ... | 0 |
It (INN), also known as sulphasomidine (BAN until 2003), sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial. It is closely related to sulfadimidine. | It , or 9H-fluorene is an organic compound with the formula (CH)CH. It forms white crystals that exhibit a characteristic, aromatic odor similar to that of naphthalene. It has a violet fluorescence, hence its name. For commercial purposes it is obtained from coal tar. It is insoluble in water and soluble in many organi... | 0 |
It is an azaspiro compound, an oxaspiro compound and a steroid. | It, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. Specifically it is used to help examine the back of the eye. It is applied as eye drops. Effects occur within 40 minutes and last for up to a day.
Common side effects include blurry visio... | 0 |
An iodate is the polyatomic anion with the formula . It is the most common form of iodine in nature, as it comprises the major iodine-containing ores. It salts are often colorless. They are the salts of iodic acid. | 2-oxoadipic acid is an oxo dicarboxylic acid that is adipic acid substituted by an oxo group at position 2. It has a role as a mouse metabolite and a human urinary metabolite. It is functionally related to an adipic acid. It is a conjugate acid of a 2-oxoadipate(2-). | 0 |
It is a furanocoumarin. | It is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid. | 0 |
It is a capsaicinoid and analog and congener of capsaicin in chili peppers (Capsicum). Like capsaicin, it is an irritant. It accounts for about 22% of the total capsaicinoid mixture and has the same pungency as capsaicin. Pure dihydrocapsaicin is a lipophilic colorless odorless crystalline to waxy compound. It is solu... | It, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression. Its effects may take up to four weeks, but can also manifest as early as one to two weeks. It is often used in cases of depression complicated by anxiety or insomnia. The eff... | 0 |
It is a natural product found in Bletilla striata and Dioscorea alata with data available. | It is a carbazole alkaloid isolated from the curry tree (Murraya koenigii) along with the related alkaloids mahanimbine, koenimbine, isomahanine, mahanine, and others.
A 2011 study of girinimbine found that it inhibited the growth and induced apoptosis in human hepatocellular carcinoma, Hep G2 cells in vitro. | 0 |
It is a monocarboxylic acid anion. It has a role as a human metabolite. It is a conjugate base of an acrylic acid. | It, sold under the brand name Hycamtin among others, is a chemotherapeutic agent medication that is a topoisomerase inhibitor. It is a synthetic, water-soluble analog of the natural chemical compound camptothecin. It is used in the form of its hydrochloride salt to treat ovarian cancer, lung cancer and other cancer ty... | 0 |
It is a natural product found in Aspergillus malignus, Rauvolfia serpentina, and other organisms with data available. | It is an alkaloid ester, a methyl ester, a benzoate ester, an organic heteropentacyclic compound and a yohimban alkaloid. It derives from a hydride of a yohimban. | 1 |
It is a monocarboxylic acid. | Se-methylselenocysteine is an alpha-amino acid compound having methylselanylmethyl as the side-chain. It has a role as an antineoplastic agent and a human metabolite. It is a member of selenocysteines and a non-proteinogenic alpha-amino acid. It is a conjugate base of a Se-methylselenocysteinium. It is a conjugate acid... | 0 |
It is a 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile that has S-configuration at the chiral centre. It is the active enantiomer of citalopram. It has a role as an antidepressant and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. It is a conjugate base of an escitalopram(1+)... | It is a 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia. It has a role as a sedative, a GABAA receptor agonist and an anxiolytic drug. It is a 1,4-benzodiazepinon... | 0 |
It, often known by the brand name Fazor is a plant growth regulator that reduces growth through preventing cell division but not cell enlargement. It is applied to the foliage of potato, onion, garlic and carrot crops to prevent sprouting during storage. It can also be used to control volunteer potatoes that are left i... | It is an alkaloid. | 0 |
It is an alkaloid. | It is a natural product found in Allium ursinum, Allium ampeloprasum, and other organisms with data available. | 0 |
It is a proline derivative that is 4-(phenylsulfanyl)-L-proline in which the amine proton is replaced by a (2S)-3-(benzoylsulfanyl)-2-methylpropanoyl group. A prodrug for zofenoprilat. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an apoptosis inhibitor, a cardioprotective agent, an anticonvulsant... | It is an organochlorine compound. | 0 |
It is a natural product found in Paraburkholderia with data available. | It is a synthetic organochloride insecticide, now obsolete. Tradenames for methoxychlor include Chemform, Maralate, Methoxo, Methoxcide, Metox, and Moxie. | 0 |
It is an organic compound related to the water-soluble compound PABA (4-aminobenzoic acid) that is used as an ingredient in some sunscreens. This yellowish water-insoluble oily liquid is an ester formed by the condensation of 2-ethylhexanol with dimethylaminobenzoic acid. Other names for padimate O include 2-ethylhex... | It is an organic compound with the formula A white solid, it is one of the isomers of methylbenzenediol. | 0 |
It is an aryl sulfate that is indoxyl in which the hydroxyl hydrogen is substituted by a sulfo group. It has a role as a human metabolite. It is a member of indoles and an aryl sulfate. It is functionally related to an indoxyl. It is a conjugate acid of an indoxyl sulfate(1-). | It is a pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and ... | 0 |
It is a fatty amide. | It is a quinolinemonocarboxylic acid that is quinoline substituted by 2'-fluoro[1,1'-biphenyl]-4-yl, methyl, carboxy and fluoro groups at positions 2, 3, 4, and 6, respectively. It is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. The compound exhibits anti... | 0 |
It (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class. It is a congener and ring-opened analogue of phenytoin (a hydantoin), and is structurally related to the barbiturates and to other hydantoins. It was introduced in 1949 for the treatment of epile... | It is a chromone derivative, a phenolic compound found in cloves. It is also one of the compounds responsible for bitterness in carrots. | 0 |
It is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other. It has a role as a cofactor, a carcinogenic agent, an Escherichia coli metabolite, a human xenobiotic metabolite, a skin lightening agent, an antioxidant and a mouse metabolite. It is a benzenediol and a member of hydroqui... | It is an aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union. It has a role as a carotogenesis inhibitor, an antioxidant, an EC 1.3.99.29 [phytoene desaturase (... | 0 |
It is a member of naphthols. | It, or allenoic acid, is a synthetic, nonsteroidal estrogen discovered in 1947 or 1948 that, although studied clinically, was never marketed. It is an open-ring or seco-analogue of steroidal estrogens like estrone and equilenin. The compound was named after Edgar Allen, one of the pioneers in estrogen research. Althoug... | 1 |
It is an organic molecular entity. | It is a member of the class of coformycins that is coformycin in which the hydroxy group at position 2' is replaced with a hydrogen. It is a drug used for the treatment of hairy cell leukaemia. It has a role as an EC 3.5.4.4 (adenosine deaminase) inhibitor, an antineoplastic agent, an antimetabolite, a bacterial metabo... | 0 |
It is a natural product found in Homo sapiens and Caenorhabditis elegans with data available. | It (contracted from ) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. It was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetam... | 0 |
It, sold under the brand name Moban, is an antipsychotic which is used in the United States in the treatment of schizophrenia. It works by blocking the effects of dopamine in the brain, leading to diminished symptoms of psychosis. It is rapidly absorbed when taken orally.
It is sometimes described as a typical antipsyc... | It is a member of indoles. | 1 |
It is a natural product found in Lactuca saligna, Picris hieracioides, and other organisms with data available. | It is an onium cation obtained by protonation of ammonia. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a cofactor. It is a nitrogen hydride, an onium cation and a monovalent inorganic cation. It is a conjugate acid of an ammonia. | 0 |
It is a naturally occurring estrogen sex hormone found in horses as well as a medication. It is one of the estrogens present in the estrogen combination drug preparations known as conjugated estrogens (CEEs; e.g. Premarin) and esterified estrogens (EEs; e.g. Estratab, Menest). CEEs is the most commonly used form of est... | It is a dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid. It has a role as a plant metabolite. It is a member of benzoic acids, a dimethoxybenzene and a member of phenols. It is functionally related to a gallic acid. It is a conjugate acid of a syringate. | 0 |
It is a catecholamine. | It is a member of benzenes. | 0 |
It is a natural product found in Pinus densiflora, Cyperus aromaticus, and other organisms with data available. | It is a natural product found in Staphisagria macrosperma with data available. | 0 |
It is a natural product found in Artemia salina with data available. | It is an alpha-amino acid ester. | 0 |
It is an aromatic ketone that consists of benzene substituted by a pentanoyl group. It has a role as a volatile oil component and a plant metabolite. | It is a 20-oxo steroid. | 0 |
It is a diarylmethane. | It is a natural product found in Camellia sinensis, Raphanus sativus var. sativus, and other organisms with data available. | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.