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The Orbiting Carbon Observatory-3 (OCO-3) is a NASA-JPL instrument designed to measure carbon dioxide in Earths atmosphere. The instrument is mounted on the Japanese Experiment Module-Exposed Facility on board the International Space Station (ISS). OCO-3 was scheduled to be transported to space by a SpaceX Dragon from ... | 0 | Greenhouse Gases |
Escitalopram increases intrasynaptic levels of the neurotransmitter serotonin by blocking the reuptake of the neurotransmitter into the presynaptic neuron. Over time, this leads to a downregulation of pre-synaptic 5-HT receptors, which is associated with an improvement in passive stress tolerance, and delayed downstrea... | 1 | Enantiopure drugs |
In 2004, separate civil suits alleging illegal marketing of citalopram and escitalopram for use by children and teenagers by Forest were initiated by two whistleblowers: a physician named Joseph Piacentile and a Forest salesman named Christopher Gobble. In February 2009, the suits were joined. Eleven states and the Dis... | 1 | Enantiopure drugs |
UNEP banned the use of Halon gases in the Montreal Protocol treaty in 1987 due to ozone depletion and the ozone-depleting effect of Halon gases. Developing countries were granted an extension to still use Halon until 2010. After 2010 UNEP recommended that those countries replace Halon with ozone friendly alternatives. | 0 | Greenhouse Gases |
After an intake of 1.5 mg levonorgestrel in clinical trials, very common side effects (reported by 10% or more) included: hives, dizziness, hair loss, headache, nausea, abdominal pain, uterine pain, delayed menstruation, heavy menstruation, uterine bleeding, and fatigue; common side effects (reported by 1% to 10%) incl... | 1 | Enantiopure drugs |
With a relatively low global warming potential (GWP) index of 124 and favorable thermophysical properties, 1,1-difluoroethane has been proposed as an environmentally friendly alternative to R134a. Despite its flammability, R152a also presents operating pressures and volumetric cooling capacity (VCC) similar to R134a so... | 0 | Greenhouse Gases |
NASA Launch Services Program (LSP) investigators have determined the technical root cause for the Taurus XL launch failures of NASAs Orbiting Carbon Observatory (OCO) and Glory missions in 2009 and 2011, respectively: faulty materials provided by aluminium manufacturer, Sapa Profiles, Inc. (SPI). LSPs technical investi... | 0 | Greenhouse Gases |
Clean agent FS 49 C2 is an environmentally engineered, human safe, fast acting Clean Agent fire extinguishing gas for gaseous fire suppression installed in a suited fire suppression system. The gas consists of tetrafluoroethane, pentafluoroethane and carbon dioxide.
FS 49 C2 maintains breathable concentrations of oxy... | 0 | Greenhouse Gases |
Esketamine is approved under the brand name Spravato in the form of a nasal spray added to a conventional antidepressant as a therapy for treatment-resistant depression (TRD) as well as major depressive disorder (MDD) associated with suicidal ideation or behavior in adults in the United States. In the clinical trials t... | 1 | Enantiopure drugs |
Hydrofluorocarbons are included in the Kyoto Protocol and are regulated under the Kigali Amendment to the Montreal Protocol due to their very high Global Warming Potential and the recognition of halocarbon contributions to climate change.
On September 21, 2007, approximately 200 countries agreed to accelerate the elimi... | 0 | Greenhouse Gases |
Carbon tetrachloride was originally synthesized in 1820 by Michael Faraday, who named it "protochloride of carbon", by decomposition of hexachloroethane ("perchloride of carbon") which he synthesized by chlorination of ethylene. The protochloride of carbon has been previously misidentified as tetrachloroethylene becaus... | 0 | Greenhouse Gases |
In January 2017, the US Food and Drug Administration approved an over-the-counter preparation. Levocetirizine had previously received authorization by the FDA as a prescription drug in 2007, having already been brought to market throughout much of Europe. In India, a prescription-only drug containing levocetirizine hyd... | 1 | Enantiopure drugs |
Schotten–Baumann reaction between 4-nitro-3-(trifluoromethyl)aniline [393-11-3] (1) with isobutanoyl chloride [79-30-1] (2) in the presence of triethylamine. | 1 | Enantiopure drugs |
Water molecules stay close to each other (cohesion), due to the collective action of hydrogen bonds between water molecules. These hydrogen bonds are constantly breaking, with new bonds being formed with different water molecules; but at any given time in a sample of liquid water, a large portion of the molecules are h... | 0 | Greenhouse Gases |
It is prepared by electrofluorination of tributylamine using hydrogen fluoride as solvent and source of fluorine: | 0 | Greenhouse Gases |
Side effects include amenorrhea, gynecomastia, galactorrhea, changes in libido, and neuroleptic malignant syndrome. In the U.S., as of 2013 only one case of adverse reaction to levosulpiride had been recorded on the FDA Adverse Event Reporting System Database. A case of rapid onset resistant dystonia caused by low dose... | 1 | Enantiopure drugs |
Inhalation of chloromethane gas produces central nervous system effects similar to alcohol intoxication. The TLV is 50 ppm and the MAC is the same. Prolonged exposure may have mutagenic effects. | 0 | Greenhouse Gases |
The North Australian Pastoral Company (NAPCO) is a large, privately owned, Australian cattle company which operates 13 cattle stations (as well as the Wainui farm and feedlot) covering over 60,000 km, managing about 200,000 cattle, in Queensland and the Northern Territory. It produces beef cattle which are grass fed a... | 0 | Greenhouse Gases |
Cloxacillin was discovered and developed by Beecham (now GlaxoSmithKline).
It is sold under a number of trade names, including Cloxapen, Cloxacap, Tegopen and Orbenin. | 1 | Enantiopure drugs |
Chiral drugs with stereo-labile configuration are likely to undergo interconversion of the enantiomers that may be enzymatic (biological) or non-enzymatic. Enzyme-mediated conversion is the process of chiral inversion that happens in a living organism. Non-enzymatic inversion of drugs is important and relevant in the p... | 1 | Enantiopure drugs |
Levoamphetamine{{#tag:ref|Synonyms and alternate spellings include: (IUPAC name), levamfetamine (International Nonproprietary Name [INN]), , , , and is a central nervous system (CNS) stimulant known to increase wakefulness and concentration in association with decreased appetite and fatigue. Pharmaceuticals that cont... | 1 | Enantiopure drugs |
Escitalopram is sold under many brand names worldwide such as Cipralex, Lexapro, Lexam, Mozarin, Aciprex, Depralin, Ecytara, Elicea, Gatosil, Nexpram, Nexito, Nescital, Szetalo, Stalopam, Pramatis, Betesda, Scippa and Rexipra. | 1 | Enantiopure drugs |
Drospirenone is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy and in menopausal hormone therapy, among other uses. It is available both alone under the brand name Slynd and in combination with an estrogen under the brand name Yasmin among others. The medication is an ... | 1 | Enantiopure drugs |
The absorption of levetiracetam tablets and oral solution is rapid and essentially complete. The bioavailability of levetiracetam is close to 100 percent, and the effect of food on absorption is minor. | 1 | Enantiopure drugs |
* The burning of long-buried fossil fuels releases containing carbon of different isotopic ratios to those of living plants, enabling distinction between natural and human-caused contributions to concentration.
* There are higher atmospheric concentrations in the Northern Hemisphere, where most of the world's popula... | 0 | Greenhouse Gases |
The dextrorotary (+)- or d- enantiomer is (1S,2S)-pseudoephedrine, whereas the levorotating (−)- or l- form is (1R,2R)-pseudoephedrine.
In the outdated system (+)-pseudoephedrine is also referred to as pseudoephedrine and (−)-pseudoephedrine as pseudoephedrine (in the Fisher projection then the phenyl ring is drawn at... | 1 | Enantiopure drugs |
CFC-113 was one of the most heavily produced CFCs. In 1989, an estimated 250,000 tons were produced. It has been used as a cleaning agent for electrical and electronic components. CFC-113’s low flammability and low toxicity made it ideal for use as a cleaner for delicate electrical equipment, fabrics, and metals. It wo... | 0 | Greenhouse Gases |
During the early Eocene, the continental configuration was such that the Arctic sea was almost entirely cut off from the wider oceans. This meant that mixing — provided today by deep water currents such as the Gulf Stream — did not occur, leading to a stratified water column resembling today's Black Sea.
High temperat... | 0 | Greenhouse Gases |
Carbon tetrachloride was widely used as a fumigant to kill insect pests in stored grain. It was employed in a mixture known as 80/20, that was 80% carbon tetrachloride and 20% carbon disulfide. The United States Environmental Protection Agency banned its use in 1985.
Another carbon tetrachloride fumigant preparation mi... | 0 | Greenhouse Gases |
OCO-3 is constructed from spare equipment from the OCO-2 mission. Thus its physical characteristics are similar, but with some adaptations. A 2-axis pointing mirror was added, which will allow targeting of cities and other areas on order of for area mapping (also called "snapshot mode"). A resolution context camera w... | 0 | Greenhouse Gases |
Animal and human data have revealed evidence of harm to the embryo and teratogenicity associated with ACE inhibitors. | 1 | Enantiopure drugs |
The age of a water parcel can be estimated by the CFC partial pressure (pCFC) age or SF partial pressure (pSF) age. The pCFC age of a water sample is defined as:
where [CFC] is the measured CFC concentration (pmol kg) and F is the solubility of CFC gas in seawater as a function of temperature and salinity. The CFC part... | 0 | Greenhouse Gases |
Drospirenone is an antagonist of the AR, the biological target of androgens like testosterone and dihydrotestosterone (DHT). It has about 1 to 65% of the affinity of the synthetic anabolic steroid metribolone for the AR. The medication is more potent as an antiandrogen than spironolactone, but is less potent than cypro... | 1 | Enantiopure drugs |
The density of water is about : this relationship was originally used to define the gram. The density varies with temperature, but not linearly: as the temperature increases, the density rises to a peak at and then decreases; the initial increase is unusual because most liquids undergo thermal expansion so that the de... | 0 | Greenhouse Gases |
Pseudoephedrine is contraindicated in patients with diabetes mellitus, cardiovascular disease, severe or uncontrolled hypertension, severe coronary artery disease, prostatic hypertrophy, hyperthyroidism, closed angle glaucoma, or by pregnant women. The safety and effectiveness of nasal decongestant use in children is u... | 1 | Enantiopure drugs |
An important feature of water is its polar nature. The structure has a bent molecular geometry for the two hydrogens from the oxygen vertex. The oxygen atom also has two lone pairs of electrons. One effect usually ascribed to the lone pairs is that the H–O–H gas-phase bend angle is 104.48°, which is smaller than the ty... | 0 | Greenhouse Gases |
The most common adverse effects of levetiracetam treatment include CNS effects such as somnolence, decreased energy, headache, dizziness, mood swings and coordination difficulties. These adverse effects are most pronounced in the first month of therapy. About 4% of patients dropped out of pre-approval clinical trials d... | 1 | Enantiopure drugs |
Fine particles dispersed in the atmosphere can serve as cloud condensation nuclei and thereby cause marine cloud brightening
Eventually all FeCl particles are washed out of the air and fall on land or water, where they dissolve into iron compounds and salt.
Iron salt aerosols may also therefore contribute to iron ferti... | 0 | Greenhouse Gases |
Levomilnacipran (brand name Fetzima) is an antidepressant which was approved in the United States in 2013 for the treatment of major depressive disorder (MDD) in adults. It is the levorotatory enantiomer of milnacipran, and has similar effects and pharmacology, acting as a serotonin–norepinephrine reuptake inhibitor (S... | 1 | Enantiopure drugs |
R-454B is not the only blend of R-32 and R-1234yf to be proposed as a refrigerant. Other blends include R-454A (35 percent R-32, 65 percent R-1234yf) and R-454C (21.5 percent R-32, 78.5 percent R1234yf). There are also several blends that include a third component. | 0 | Greenhouse Gases |
NAPCO was the first company which was able to progress to registration of final 14001 certification. This was primarily due to the increased costs of surveillance audits and an absence of market incentives to promote this certificate as the gold standard within the Australian beef industry. A ‘cluster approach’ was uti... | 0 | Greenhouse Gases |
Many marine organisms biosynthesize halomethanes, especially bromine-containing compounds. Small amounts of chloromethanes arise from the interaction of chlorine sources with various carbon compounds. The biosyntheses of these halomethanes are catalyzed by the chloroperoxidase and bromoperoxidase enzymes, respectively.... | 0 | Greenhouse Gases |
Dexmedetomidine is a highly selective α-adrenergic agonist. It possesses an α:α selectivity ratio of 1620:1, making it eight times more selective for the α-receptor than clonidine. Unlike opioids and other sedatives such as propofol, dexmedetomidine is able to achieve its effects without causing respiratory depression... | 1 | Enantiopure drugs |
Benzylpenicillin, also known as penicillin G (PenG) or BENPEN, is an antibiotic used to treat a number of bacterial infections. This includes pneumonia, strep throat, syphilis, necrotizing enterocolitis, diphtheria, gas gangrene, leptospirosis, cellulitis, and tetanus. It is not a first-line agent for pneumococcal meni... | 1 | Enantiopure drugs |
Most of the methyl chloride present in the environment ends up being released to the atmosphere. After being released into the air, the atmospheric lifetime of this substance is about 10 months with multiple natural sinks, such as ocean, transport to the stratosphere, soil, etc.
On the other hand, when the methyl chlor... | 0 | Greenhouse Gases |
Bromochlorodifluoromethane (BCF), also referred to by the code numbers Halon 1211 and Freon 12B1, is a haloalkane with the chemical formula CFClBr. It is used for fire suppression, especially for expensive equipment or items that could be damaged by the residue from other types of extinguishers. It is stored as a liqu... | 0 | Greenhouse Gases |
The Montreal Protocol targeted 1,1,1-trichloroethane as one of those compounds responsible for ozone depletion and banned its use beginning in 1996. Since then, its manufacture and use have been phased out throughout most of the world. Its atmospheric presence has declined rapidly due to its relatively short atmospher... | 0 | Greenhouse Gases |
Both the oral and intravenous preparations of flucloxacillin are inexpensive and are available as the sodium salt flucloxacillin sodium, in capsules (250 or 500 mg), oral suspensions (125 mg/5 ml or 250 mg/5 ml), and injections (powder for reconstitution, 250, 500, 1000 and 2000 mg per vial).
Flucloxacillin is not comm... | 1 | Enantiopure drugs |
Exemestane is indicated for the adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to it for completion of a total of five consecutive years of adjuvant hormonal therapy.
US FDA approval was in October 1999.
E... | 1 | Enantiopure drugs |
A 2006 meta analysis concluded that compared to other proton pump inhibitors, esomeprazole confers a modest overall benefit in esophageal healing and symptom relief. When broken down by disease severity, the benefit of esomeprazole relative to other proton pump inhibitors was negligible in people with mild disease (num... | 1 | Enantiopure drugs |
The Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BLA) was a 2005 landmark trial that compared the effects of the established therapy of the combination of atenolol and bendroflumethiazide to the new drug combination of amlodipine and perindopril (trade names Viacoram, AceryCal etc.). The... | 1 | Enantiopure drugs |
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Water () is a polar inorganic compound that is at room temperature a tasteless and odorless liquid, which is nearly colorless apart from an inherent hint of blue. It is by far the most studied chemical compound and is described as the "universal solvent" and the "solven... | 0 | Greenhouse Gases |
Levomethorphan (LVM) (INN, BAN) is an opioid analgesic of the morphinan family that has never been marketed. It is the -stereoisomer of racemethorphan (methorphan). The effects of the two isomers of racemethorphan are quite different, with dextromethorphan (DXM) being an antitussive at low doses and a dissociative hall... | 1 | Enantiopure drugs |
In the late 19th century, scientists experimentally discovered that and do not absorb infrared radiation (called, at that time, "dark radiation"), while water (both as true vapor and condensed in the form of microscopic droplets suspended in clouds) and and other poly-atomic gaseous molecules do absorb infrared radi... | 0 | Greenhouse Gases |
Dexketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as dexketoprofen trometamol, as a prescription-only drug and in Latin America as Enantyum, produced by Menarini. Also, in Italy and Spain it is available as an over-the-... | 1 | Enantiopure drugs |
As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against gram-positive organisms. Some gram-negative organisms such as Neisseria gonorrhoeae and Leptospira weilii are also reported to be susceptible to benzylpenicillin. | 1 | Enantiopure drugs |
Dextroamphetamine is used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy (a sleep disorder), and is sometimes prescribed for depression and obesity. | 1 | Enantiopure drugs |
Flutamide has been found to be effective in the treatment of hirsutism (excessive body/facial hair growth) in numerous studies. It possesses moderate effectiveness for this indication, and the overall quality of the evidence is considered to be moderate. The medication shows equivalent or superior effectiveness to othe... | 1 | Enantiopure drugs |
Drospirenone binds with high affinity to the progesterone receptor (PR) and mineralocorticoid receptor (MR), with lower affinity to the androgen receptor (AR), and with very low affinity to the glucocorticoid receptor (GR). It is an agonist of the PR and an antagonist of the MR and AR, and hence is a progestogen, antim... | 1 | Enantiopure drugs |
Meropenem is administered intravenously as an aqueous solution. Meropenem is stored in vials as white crystalline powder (containing meropenem as the trihydrate blended with anhydrous sodium carbonate). For intravenous administration, the powder is dissolved in 5% monobasic potassium phosphate solution, since meropenem... | 1 | Enantiopure drugs |
Eszopiclone acts on benzodiazepine binding site situated on GABA neurons as a positive allosteric modulator.
Eszopiclone is rapidly absorbed after oral administration, with serum levels peaking between .45 and 1.3 hours. The elimination half-life of eszopiclone is approximately 6 hours and it is extensively metabolized... | 1 | Enantiopure drugs |
Cilazapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure.
It was patented in 1982 and approved for medical use in 1990. | 1 | Enantiopure drugs |
Piperacillin irreversibly binds to the enzyme penicillin-binding proteins, inhibiting the biosynthesis of bacterial cell walls. | 1 | Enantiopure drugs |
People who are taking meperidine, tramadol, methadone, propoxyphene, dextromethorphan, St. John’s wort, cyclobenzaprine, or another MAO inhibitor should not take rasagiline.
The FDA drug label carries a warning of the risk of serotonin syndrome when rasagiline is used with antidepressants or with meperidine. However ... | 1 | Enantiopure drugs |
Dextroamphetamine is the active metabolite of the prodrug lisdexamfetamine (L-lysine-dextroamphetamine), available by the brand name Vyvanse (Elvanse in the European market) (Venvanse in the Brazil market) (lisdexamfetamine dimesylate). Dextroamphetamine is liberated from lisdexamfetamine enzymatically following contac... | 1 | Enantiopure drugs |
In veterinary medicine, ampicillin is used in cats, dogs, and farm animals to treat:
* Anal gland infections
* Cutaneous infections, such as abscesses, cellulitis, and pustular dermatitis
* E. coli and Salmonella infections in cattle, sheep, and goats (oral form). Ampicillin use for this purpose had declined as bacteri... | 1 | Enantiopure drugs |
In E for Ecstasy (a book examining the uses of the street drug ecstasy in the UK) the writer, activist and ecstasy advocate Nicholas Saunders highlighted test results showing that certain consignments of the drug also contained selegiline. Consignments of ecstasy known as "Strawberry" contained what Saunders described ... | 1 | Enantiopure drugs |
In 2005, Myriad Genetics reported the results of its Phase II clinical trial of Flurizan; it was the largest ever Alzheimers drug treatment trial using R-flurbiprofen. Patients were split into three treatment groups, receiving placebo, 400 or 800 mg R-flurbiprofen twice daily for a year. Result from this trial showed ... | 1 | Enantiopure drugs |
OCOs measurements are designed to be accurate enough to show for the first time the geographic distribution of carbon dioxide sources and sinks on a regional scale. The data is planned to improve the understanding of the global carbon cycle, the natural processes and human activities that influence the abundance and di... | 0 | Greenhouse Gases |
Perfluorohexane (), or tetradecafluorohexane, is a fluorocarbon. It is a derivative of hexane in which all the hydrogen atoms are replaced by fluorine atoms. It is used in one formulation of the electronic cooling liquid/insulator Fluorinert for low-temperature applications due to its low boiling point of 56 °C and fre... | 0 | Greenhouse Gases |
A single water molecule can participate in a maximum of four hydrogen bonds because it can accept two bonds using the lone pairs on oxygen and donate two hydrogen atoms. Other molecules like hydrogen fluoride, ammonia, and methanol can also form hydrogen bonds. However, they do not show anomalous thermodynamic, kinetic... | 0 | Greenhouse Gases |
In liquid water there is some self-ionization giving hydronium ions and hydroxide ions.
The equilibrium constant for this reaction, known as the ionic product of water, , has a value of about at 25 °C. At neutral pH, the concentration of the hydroxide ion () equals that of the (solvated) hydrogen ion (), with a value ... | 0 | Greenhouse Gases |
Oxacillin, through its β-lactam ring, covalently binds to penicillin-binding proteins, which are enzymes involved in the synthesis of the bacterial cell wall. This binding interaction interferes with the transpeptidation reaction and inhibits the synthesis of peptidoglycan, a prominent component of the cell wall. By de... | 1 | Enantiopure drugs |
The concentration of HCFC-141b in the atmosphere grew to near 25 parts per trillion by year 2016. It has an ozone depletion potential (ODP) of 0.12. This is low compared to the ODP=1 of trichlorofluoromethane (CFC-11, R-11), which also grew about ten times more abundant in the atmosphere prior to introduction of HFC... | 0 | Greenhouse Gases |
Products using amphetamine base are now marketed. Dyanavel XR, a liquid suspension form became available in 2015, and contains about 24% levoamphetamine. Adzenys XR, an orally dissolving tablet came to market in 2016 and contains 25% levoamphetamine. | 1 | Enantiopure drugs |
It is well documented that (R)-enantiomers of profens in the presence of coenzyme A (CoA), adenosine triphosphate (ATP) and Mg are converted to active (S)-forms. The pathways of chiral inversion is illustrated taking ibuprofen as the prototype, in the scheme below.
The pathway consists mainly of three steps:
# Stereose... | 1 | Enantiopure drugs |
Eslicarbazepine acetate is absorbed to at least 90% from the gut, independently of food intake. It is quickly metabolised to eslicarbazepine, so that the original substance cannot be detected in the bloodstream. Peak plasma levels of eslicarbazepine are reached after 2–3 (1–4) hours, and plasma protein binding is somew... | 1 | Enantiopure drugs |
The repulsive effects of the two lone pairs on the oxygen atom cause water to have a bent, not linear, molecular structure, allowing it to be polar. The hydrogen–oxygen–hydrogen angle is 104.45°, which is less than the 109.47° for ideal sp hybridization. The valence bond theory explanation is that the oxygen atoms lone... | 0 | Greenhouse Gases |
The production of BCF and similar chlorofluorocarbons has been banned in most countries since January 1, 1994 as part of the Montreal Protocol on ozone depleting substances. Halon 1211 is also a potent greenhouse gas with a 100-year global warming potential 2,070 times that of carbon dioxide and an atmospheric lifetime... | 0 | Greenhouse Gases |
Drospirenone has been found to stimulate the proliferation and migration of breast cancer cells in preclinical research, similarly to certain other progestins. However, some evidence suggests that drospirenone may do this more weakly than certain other progestins, like medroxyprogesterone acetate. The combination of es... | 1 | Enantiopure drugs |
The roles of regulatory agencies also continue to evolve with respect to the development of chiral switches. An interesting concept brought up in the FDA policy is that of "bridging studies". When a sponsor/innovator seeks to develop a single enantiomer from a racemic drug, the regulatory agencies demand them to conduc... | 1 | Enantiopure drugs |
emissions have also led to the stratosphere contracting by 400 meters since 1980, which could affect satellite operations, GPS systems and radio communications. | 0 | Greenhouse Gases |
Ketamine is a widely used anaesthetic agent. It is a chiral molecule that is administered as a racemate. Studies show that (S)-(+)-ketamine is the active anaesthetic and the undesired side-effects (hallucination and agitation) reside in the distomer, (R)-(-)-ketamine. | 1 | Enantiopure drugs |
The natural flows of carbon between the atmosphere, ocean, terrestrial ecosystems, and sediments are fairly balanced; so carbon levels would be roughly stable without human influence. Carbon dioxide is removed from the atmosphere primarily through photosynthesis and enters the terrestrial and oceanic biospheres. Carbon... | 0 | Greenhouse Gases |
Magma contains dissolved volatile components, as described above. The solubilities of the different volatile constituents are dependent on pressure, temperature and the composition of the magma. As magma ascends towards the surface, the ambient pressure decreases, which decreases the solubility of the dissolved volatil... | 0 | Greenhouse Gases |
The bioavailability of levonorgestrel is approximately 95% (range 85 to 100%). The plasma protein binding of levonorgestrel is about 98%. It is bound 50% to albumin and 48% to SHBG. Levonorgestrel is metabolized in the liver, via reduction, hydroxylation, and conjugation (specifically glucuronidation and sulfation). Ox... | 1 | Enantiopure drugs |
Derived from “the addition of a hydrophilic heterocyclic group to the α-amino group of ampicillin”, the structure consists of a thiazolidine ring conjoined to a β-lactam ring contained within several ring compounds. The addition of this substituent increases the compounds affinity to penicillin-binding protein PBP-3, i... | 1 | Enantiopure drugs |
Estimates in 2023 found that the current carbon dioxide concentration in the atmosphere may be the highest it has been in the last 14 million years. However the IPCC Sixth Assessment Report estimated similar levels 3 to 3.3 million years ago in the mid-Pliocene warm period. This period can be a proxy for likely climate... | 0 | Greenhouse Gases |
5α-Dihydrolevonorgestrel (5α-DHLNG) is an active metabolite of the progestin levonorgestrel which is formed by 5α-reductase. It has about one-third of the affinity of levonorgestrel for the progesterone receptor. In contrast to levonorgestrel, the compound has both progestogenic and antiprogestogenic activity, and henc... | 1 | Enantiopure drugs |
Selegiline belongs to the phenethylamine and amphetamine chemical families. It is also known as -deprenyl, as well as (R)-(–)-N,α-dimethyl-N-(2-propynyl)phenethylamine or (R)-(–)-N-methyl-N-2-propynylamphetamine. The compound is a derivative of levomethamphetamine (-methamphetamine) with a propargyl group attached to t... | 1 | Enantiopure drugs |
There were four named penicillins at the time penicillin V was discovered (penicillins I, II, III, IV), however, Penicillin V was named "V" for Vertraulich (German for confidential); it was not named for the Roman numeral "5".
Penicillin VK is the potassium salt of penicillin V (K is the chemical symbol for potassium). | 1 | Enantiopure drugs |
Formylation of octabase prior to cyclization avoids ether cleavage as a side reaction and yields higher than without N-substitution or N-methylation. In this example, the purification was done by formation of a brucine salt.
This process has also been patented by Roche. | 1 | Enantiopure drugs |
Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. For heart failure, it is generally used with a diuretic, such as furosemide. It is given by mouth or by injection into a vein. Onset of effects are typ... | 1 | Enantiopure drugs |
Overdose of levonorgestrel as an emergency contraceptive has not been described. Nausea and vomiting might be expected. | 1 | Enantiopure drugs |
Sublimation is the process by which water molecules directly leave the surface of ice without first becoming liquid water. Sublimation accounts for the slow mid-winter disappearance of ice and snow at temperatures too low to cause melting. Antarctica shows this effect to a unique degree because it is by far the contine... | 0 | Greenhouse Gases |
There are no known contraindication to the use of dexmedetomidine. It has a biphasic effect on blood pressure with lower readings at lower drug concentrations and higher readings at higher concentrations. Common side effects include: hypotension, hypertension, with slight decreases in heart rate, arrhythmias, and hypox... | 1 | Enantiopure drugs |
The Advisory Group on Greenhouse Gases, created in 1986, was an advisory body for the review of studies into the greenhouse effect. The group was created by the International Council of Scientific Unions, the United Nations Environment Programme, and the World Meteorological Organization to follow up on the recommenda... | 0 | Greenhouse Gases |
Cefuroxime is active against many bacteria including susceptible strains of Staphylococci and Streptococci, as well as a range of gram negative organisms. As with the other cephalosporins, it is susceptible to beta-lactamase, although as a second-generation variety, it is less so. Hence, it may have greater activity ag... | 1 | Enantiopure drugs |
Dexlansoprazole was approved by the U.S. Food and Drug Administration (FDA) in 2009, and was approved in Canada in 2010 and in Mexico in 2011.
Since Kapidex was approved in 2009, there have been reports of dispensing errors because of confusion with the drugs Casodex (bicalutamide) and Kadian (morphine), which have ver... | 1 | Enantiopure drugs |
In 1987, an elderly couple was exposed to sulfuryl fluoride in their house already cleared for reentry. While the fumigation company opened windows and doors, and aerated the house with fans, sulfuryl fluoride level was not measured. It was not detected when the air was sampled 12 days after aeration. The couple experi... | 0 | Greenhouse Gases |
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