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Carbon Emissions of the Tourism Telecoupling System: Theoretical Framework, Model Specification and Synthesis Effects Citation: Duan, X.; Zhang, J.; Sun, P.; Zhang, H.; Wang, C.; Sun, Y.-Y.; Lenzen, M.; Malik, A.; Cao, S.; Kan, Y. Carbon Emissions of the Tourism Telecoupling System: Theoretical Framework, Model Specif...
Intraocular lens power calculation in eyes with previous corneal refractive surgery Intraocular lens (IOL) power calculation after corneal refractive surgery (CRS) becomes an expanding challenge for ophthalmologists as more and more cataract surgeries after CRS are required. These patients typically also have high exp...
Solving yeast jigsaw puzzles over a glass of wine ## Solving scientific puzzles Oddly, Pasteur and Spilsbury have much in common. In their indomitable quest to solve challenging problems, both were interested in uncovering every bit of detail of the "problem" and in piecing the "Big Picture" together. Their approac...
Spontaneous subdiaphragmatic bar migration after pectus excavatum treatment ## Summary A case of an adolescent boy with persistent thoracic symptoms and recurrence of pectus excavatum (after previous treatment with the Nuss procedure) is presented. During thoracoscopic revision, subdiaphragmatic migration of the imp...
Long-term efficacy of alemtuzumab in polymyositis References1 Rovin BH, Furie R, Latinis K et al. Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study. Arthritis Rheum 2012;64:121526. 2 Merrill JT, Neuwelt CM, Wallace DJ et al. Effi...
Tissue fibrocytes in patients with mild asthma: A possible link to thickness of reticular basement membrane? Background: Myofibroblasts, proposed as being derived from circulating fibrocytes, are considered to be important cells in thickening of the basement membrane in patients with asthma. We have studied the correl...
Role of Complement in Multiorgan Failure Multiorgan failure (MOF) represents the leading cause of death in patients with sepsis and systemic inflammatory response syndrome (SIRS) following severe trauma. The underlying immune response is highly complex and involves activation of the complement system as a crucial enti...
Grade IV blunt splenic injury – the role of proximal angioembolization. A case report and review of literature The authors present a case of grade IV traumatic spleen rupture (AAST-OIS) and an Injury Severity Score of 21 and a Revised Trauma Score RTS=7.841, which was managed without surgery, but with proximal splenic...
Severe obesity and diabetes insipidus in a patient with PCSK1 deficiency☆ Non-synonymous mutations affecting both alleles of PCSK1 (proprotein convertase 1/3) are associated with obesity and impaired prohormone processing. We report a proband who was compound heterozygous for a maternally inherited frameshift mutation...
Randomised controlled trial using a theory-based m-health intervention to improve physical activity and sleep health in adults: the Synergy Study protocol For peer review only -http://bmjopen.bmj.com/site/about/guidelines.xhtmlBMJ OpenSTUDY PROTOCOL 1Date: 03/08/2017; Version 1 2 3Title 4 5A randomised controlled tria...
Association of parental characteristics and emotion regulation in children and adolescents with and without psychopathology: A case-control study Association of parental characteristics and emotion regulation in children and adolescentsSupplementAs gender and age of the children seem to influence ER and parenting beha...
Examining the Potential of Developing and Implementing Use of Adiponectin-Targeted Therapeutics for Metabolic and Cardiovascular Diseases Cardiometabolic diseases encompass those affecting the heart and vasculature as well as other metabolic problems, such as insulin resistance, diabetes, and non-alcoholic fatty liver...
Clinical outcomes of helical tomotherapy for super-elderly patients with localized and locally advanced prostate cancer: comparison with patients under 80 years of age We investigated the clinical outcomes of helical tomotherapy in 23 patients aged ≥80 years with localized and locally advanced prostate cancer and comp...
Novel, disposable, self-inserted, vaginal device for the non-surgical management of pelvic organ prolapse: efficacy, safety, and quality of life Background: We evaluated a novel disposable, collapsible, ring-shaped vaginal device that is self-inserted within an applicator and removed with a string. The device was deve...
Aconite poisoning with arrhythmia and shock ## 1. Case report A 55-year-male presented in emergency department with history of epigastric burning, nausea, vomiting, dizziness, generalized paresthesia, palpitation, and profuse sweating of 2 h duration. Patient had no history of chest pain. Patient had past history of...
Mast Cell Sarcoma of the Retroperitoneum With Concurrent Systemic Mastocytosis and an Undisclosed Associated Hematologic Neoplasm: A Case Report # Introduction Mastocytosis arises from a clonal, neoplastic proliferation of mast cells that accumulate in one or more organ systems.Mast cell sarcoma (MCS) is an exceedin...
The effects of anticholinergic medications on cognition in children: a systematic review and meta-analysis Cognitive side effects of anticholinergic medications in older adults are well documented. Whether these poor cognitive outcomes are observed in children has not been systematically investigated. We aimed to cond...
Efficacy and Safety of AbobotulinumtoxinA for the Treatment of Hemiparesis in Adults with Lower Limb Spasticity Previously Treated With Other Botulinum Toxins: A Secondary Analysis of a Randomized Controlled Trial Objective: To examine the safety and efficacy of abobotulinumtoxinA in patients previously treated with b...
The Effectiveness of Planning Interventions for Improving Physical Activity in the General Population: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Planning interventions such as action planning (AP) and coping planning (CP) have been recognized as influential strategies in promoting physical ...
Idiopathic Granulomatous Hypophysitis Mimicking Pituitary Abscess Idiopathic granulomatous hypophysitis (IGH) is a rare inflammatory disease of the pituitary that commonly presents with enlargement of the pituitary gland. Clinically and radiologically, IGH is a rare sellar entity easily to be misdiagnosed as a pituita...
Flexible All-organic, All-solution Processed Thin Film Transistor Array with Ultrashort Channel Shrinking the device dimension has long been the pursuit of the semiconductor industry to increase the device density and operation speed. In the application of thin film transistors (TFTs), all-organic TFT arrays made by a...
Identification and expression of functionally conserved circadian clock genes in lichen-forming fungi Lichen-forming fungi establish stable symbioses with green algae or cyanobacteria. Many species have broad distributions, both in geographic and ecological space, making them ideal subjects to study organism-environme...
Measuring the impact and distress of health problems from the individual's perspective: development of the Perceived Impact of Problem Profile (PIPP) Background:The aim of this study was to develop and conduct preliminary validation of the Perceived Impact of Problem Profile (PIPP). Based on the biopsychosocial model ...
Pex18p and Pex21p, a Novel Pair of Related Peroxins Essential for Peroxisomal Targeting by the PTS2 Pathway We have identified ScPex18p and ScPex21p, two novel S . cerevisiae peroxins required for protein targeting via the PTS2 branch of peroxisomal biogenesis. Targeting by this pathway is known to involve the interac...
Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate ## Introductory remarks The website "Free Radical School Presentations"serves as "an archive" for many of the Free Radical School Workshop and Virtual School lectures that were organized by the Society for Redox Biology and Medicin...
One-year results of a clinical trial of olipudase alfa enzyme replacement therapy in pediatric patients with acid sphingomyelinase deficiency ## Clinical description and management of patient with anaphylactic reaction Summary A 17-month-old patient included in the Infant/early child cohort experienced a serious adv...
ZODET: Software for the Identification, Analysis and Visualisation of Outlier Genes in Microarray Expression Data Complex human diseases can show significant heterogeneity between patients with the same phenotypic disorder. An outlier detection strategy was developed to identify variants at the level of gene transcrip...
Acute acalculous cholecystitis in hospitalized patients in intensive care unit: study of 5 cases # Introduction Acute acalculous cholecystitis (AAC) is an uncommon condition characterized by gallbladder inflammation in the absence of biliary calculi or sludge [bib_ref] The increasing prevalence of acalculous cholecy...
Assessing the Accuracy of Inhomogeneous Fluid Solvation Theory in Predicting Hydration Free Energies of Simple Solutes Accurate prediction of hydration free energies is a key objective of any free energy method that is applied to modeling and understanding interactions in the aqueous phase. Inhomogeneous fluid solvati...
Increased HIV Prevention Program Coverage and Decline in HIV Prevalence Among Female Sex Workers in South India Background: As one way of assessing the impact of Avahan, the India AIDS Initiative of the Bill & Melinda Gates Foundation, we examined the association between HIV prevention program indicators and changes i...
Influence of ECAP process on mechanical and corrosion properties of pure Mg and ZK60 magnesium alloy for biodegradable stent applications # Introduction Nowadays, biomaterial technology is built on traditional permanent metallic materials including stainless steel, Nitinol and cobalt-chromium alloys. In particular, ...
Extra-Gastrointestinal Stromal Tumor (EGIST) in the Pelvis Mimicking Retroperitoneal Sarcoma Gastrointestinal stromal tumors (GISTs) are among the most common mesenchymal tumors 1 of the gastrointestinal (GI) tract; they account for approximately 3% of all GI tumors, with up to 70% found in the stomach, 25% in the sma...
Risk factors for male breast cancer. Smm.uaryRisk factors for male breast cancer were investigated in a case-control study of 21 cases and 82 controls admitted to hospital for acute, non-neoplastic, non-hormone-related diseases in the Greater Milan area between 1988 and 1994. More educated men tended to be at higher n...
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study Background: Acute capsaicinoid and capsinoid supplementation has endurance and resistance exercise be...
Reciprocal carbonyl–carbonyl interactions in small molecules and proteins Carbonyl-carbonyl n→π* interactions where a lone pair (n) of the oxygen atom of a carbonyl group is delocalized over the π* orbital of a nearby carbonyl group have attracted a lot of attention in recent years due to their ability to affect the 3...
Comparison of biodegradable and durable polymer drug-eluting stents in acute coronary syndrome: a meta-analysis ⇒ This meta-analysis included randomised controlled trials with long-term follow-ups. ⇒ The large sample size ensures adequate statistical power to detect even a small effect of interest. ⇒ Heterogeneity amo...
No Difference in Small or Large Nerve Fiber Function Between Individuals With Normal Glucose Tolerance and Impaired Glucose Tolerance OBJECTIVEdTo assess small and large nerve fiber function in people with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and type 2 diabetes (T2D).RESEARCH DESIGN AND M...
A novel phenotype of 13q12.3 microdeletion characterized by epilepsy in an Asian child: a case report Background: The microdeletion of chromosome 13 has been rarely reported. Here, we report a 14-year old Asian female with a de novo microdeletion on 13q12.3. Case presentation: The child suffered mainly from two types ...
The use of granulocyte colony-stimulating factor to increase the intensity of treatment with doxorubicin in patients with advanced breast and ovarian cancer. [bib_ref] Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells, Souza [/bib_ref] [bib_ref] Recombinant human gr...
Thinopyrum ponticum Chromatin-Integrated Wheat Genome Shows Salt-Tolerance at Germination Stage A wild wheatgrass, Thinopyrum ponticum (2n = 10x = 70), which exhibits substantially higher levels of salt tolerance than cultivated wheat, was employed to transfer its salt tolerance to common wheat by means of wide hybrid...
Realizing Innate Potential: CAR-NK Cell Therapies for Acute Myeloid Leukemia # Introduction Acute myeloid leukemia (AML), the most common acute leukemia in adults, is a biologically heterogenous disease. Genetic alterations driving proliferation or disrupting differentiation lead to the accumulation of immature blas...
Incidence of Adverse Drug Reactions in COVID‐19 Patients in China: An Active Monitoring Study by Hospital Pharmacovigilance System ## Incidence of adverse drug reactions in covid-19 patients in china: an active monitoring study by hospital pharmacovigilance system Ji Sun 1 , Xuanyu Deng 1 , Xiaoping Chen 2,3,4 , Jua...
A Rare Association of Congenital Diaphragmatic Hernia with Lower Esophageal Atresia and Perforation Congenital diaphragmatic hernia is known to be associated with esophageal atresia, which is a rare association. We report a rare occurrence of congenital diaphragmatic hernia and lower esophageal atresia. # Introductio...
Infantile systemic juvenile xanthogranuloma case with massive liver infiltration Infantile systemic juvenile xanthogranuloma (ISJXG) is an uncommon form of juvenile xanthogranuloma, a non-Langerhans cell proliferation of infancy and early childhood. In a small percentage of patients, the visceral involvement-most comm...
FAIR data representation in times of eScience: a comparison of instance-based and class-based semantic representations of empirical data using phenotype descriptions as example Background: The size, velocity, and heterogeneity of Big Data outclasses conventional data management tools and requires data and metadata to ...
The BNT162b2 vaccine induces humoral and cellular immune memory to SARS-CoV-2 Wuhan strain and the Omicron variant in children 5 to 11 years of age SARS-CoV-2 mRNA vaccines prevent severe COVID-19 by generating immune memory, comprising specific antibodies and memory B and T cells. Although children are at low risk of...
The cellular environment shapes the nuclear pore complex architecture Nuclear pore complexes (NPCs) create large conduits for cargo transport between the nucleus and cytoplasm across the nuclear envelope (NE) 1-3 . These multi-megadalton structures are composed of about thirty different nucleoporins that are distribut...
Preferences of people with type 2 diabetes for telemedical lifestyle programmes in Germany: protocol of a discrete choice experiment Supplementary File Supplementary File 10.1136/bmjopen-2020-036995 Helpfulness of information -Enough information has been provided that you believe your question has been answered to you...
Concepts of functioning and health important to people with systemic sclerosis: a qualitative study in four European countries Objective To describe the experiences of people with systemic sclerosis (SSc) in different European countries of functioning and health and to link these experiences to the WHO International C...
CRISPR interference: a structural perspective CRISPR (cluster of regularly interspaced palindromic repeats) is a prokaryotic adaptive defence system, providing immunity against mobile genetic elements such as viruses. Genomically encoded crRNA (CRISPR RNA) is used by Cas (CRISPR-associated) proteins to target and subs...
Saved by the Scan: A Case of Early Detection of Sarcomatoid Mesothelioma # Introduction Malignant pleural mesothelioma (MPM) is an aggressive tumor originating from mesothelial cells lining the lung pleura, peritoneum, tunica vaginalis, and pericardium, listed in descending order of occurrence. The incidence of MPM ...
SLAMF8 Participates in Acute Renal Transplant Rejection via TLR4 Pathway on Pro-Inflammatory Macrophages # Introduction Kidney transplantation is the most optimal renal replacement therapy both for the quality and quantity of life that it provides and for cost effectiveness compared to classic maintenance dialysis f...
Fungal Lactamases: Their Occurrence and Function # Introduction The soil is one of the most complex habitats on earth due primarily to the diversity of microorganisms that inhabit it and the myriad biochemical products they secrete. Experiments utilizing metagenomic technologies estimate up to several million specie...
Esophageal Inlet Patch ## Clinical presentation A 65-year-old male was referred to radiology for a barium meal study with complaints of high dysphagia for solids with occasional choking and regurgitation. Chest radiography and electrocardiogram examinations were normal. The barium study was performed with rapid sequ...
The effect of the VKORC1 promoter variant on warfarin responsiveness in the Saudi WArfarin Pharmacogenetic (SWAP) cohort Warfarin is a frequently prescribed oral anticoagulant with a narrow therapeutic index, requiring careful dosing and monitoring. However, patients respond with significant inter-individual variabili...
Spotlight on adalimumab in the treatment of active moderate-to-severe hidradenitis suppurativa Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease that affects the hair follicles of the aprocrine gland-bearing anatomical areas of the body. It is characterized by deep painful nodules and ab...
Serum biomarkers confirming stable remission in inflammatory bowel disease Crohn's disease (CD) and ulcerative colitis (UC) have a chronic-remittent course. Optimal management of inflammatory bowel diseases (IBD) relies on early intervention, treat-to-target strategies and a tight disease control. However, it is chall...
CITED2 Mutation and methylation in children with congenital heart disease Background: The occurrence of Congenital Heart Disease (CHD) is resulted from either genetic or environmental factors or the both. The CITED2 gene deletion or mutation is associated with the development of cardiac malformations. In this study, w...
Long-term growth of temperate broadleaved forests no longer benefits soil C accumulation It is widely recognized that the long-term growth of forests benefits biomass carbon (C) sequestration, but it is not known whether the long-term growth of forests would also benefit soil C sequestration. We selected 79 representa...
Change in Proportional Protein Intake in a 10-Week Energy-Restricted Low- or High-Fat Diet, in Relation to Changes in Body Size and Metabolic Factors Objective: To investigate in a secondary analysis of a randomised trial the effects of a low-/ high-fat diet and reported change from baseline in energy% from protein (p...
Three-year survival and recurrence after first-ever stroke: the Joinville stroke registry Background: Data estimating the recurrence and risk of death are lacking in low and middle income countries, where two thirds of the stroke burden occurs. Previously we had shown that the incidence and mortality have been decreas...
Kissing nevus of the penis: a case report and dermatoscopic findings* Divided nevus, also known as kissing nevus, is a rare variant of congenital melanocytic nevi in which there are two adjacent nevi in areas of the body that undergo embryonic cleavage. The original description of this type of lesion was on the eyelid...
Type I Choledochal Cyst Complicated With Acute Hemorrhagic Pancreatitis: A Case Report Choledochal cysts rarely present with acute pancreatitis. We report a patient with type I choledochal cyst(s) who had concomitant acute frank hemorrhagic pancreatitis.A 14-year-old male noted with a history of recurrent abdominal pa...
Autocatalytic Activation of the Furin Zymogen Requires Removal of the Emerging Enzyme's N-Terminus from the Active Site Background: Before furin can act on protein substrates, it must go through an ordered process of activation. Similar to many other proteinases, furin is synthesized as a zymogen (profurin) which beco...
Associations between recent intimate partner violence and receipt and quality of perinatal health services in Uttar Pradesh ## Ueldkja es jk uke ------------------------------------------------------gs a es a la cks f/k fjlpz ,um de;q fuds 'kul dh áfrfuf/k gw ¡ a es a vkils åùkj áns 'k es a ánku dh tkus okyh loklf; ...
KeyPathwayMineR: De Novo Pathway Enrichment in the R Ecosystem De novo pathway enrichment is a systems biology approach in which OMICS data are projected onto a molecular interaction network to identify subnetworks representing condition-specific functional modules and molecular pathways. Compared to classical pathway...
Recurrent nonbacterial thrombotic endocarditis and stroke on anticoagulation We present a rare case of recurrent nonbacterial thrombotic endocarditis (NBTE) and stroke despite anticoagulation. A 48-year-old man with history of antiphospholipid syndrome, prior nonbacterial aortic valve endocarditis status post valve re...
Photosynthetic and Canopy Characteristics of Different Varieties at the Early Elongation Stage and Their Relationships with the Cane Yield in Sugarcane During sugarcane growth, the Early Elongation stage is critical to cane yield formation. In this study, parameters of 17 sugarcane varieties were determined at the Ear...
Predictive Power of a Body Shape Index for Development of Diabetes, Hypertension, and Dyslipidemia in Japanese Adults: A Retrospective Cohort Study Background/ObjectivesRecently, a body shape index (ABSI) was reported to predict all-cause mortality independently of body mass index (BMI) in Americans. This study aimed ...
UVR8-mediated inhibition of shade avoidance involves HFR1 stabilization in Arabidopsis ## S1 fig
Time‐resolved interaction proteomics of the GIGANTEA protein under diurnal cycles in Arabidopsis The plant-specific protein GIGANTEA (GI) controls many developmental and physiological processes, mediating rhythmic post-translational regulation. GI physically binds several proteins implicated in the circadian clock, ph...
Effect of Vitamin D on the Vaginal Health of Menopausal Women: A Systematic Review Menopause is associated with the onset of climacteric symptoms due to low estradiol levels, which may cause insufficient maturation of the vaginal mucosa. Vitamin D may regulate the growth and differentiation of cells that are adversely...
Doctor and practice characteristics associated with differences in patient evaluations of general practice Background: Variation in patients' evaluation due to general practitioner (GP) and practice factors may provide information useful in a quality improvement context. However, the extent to which differences in pat...
Same features, different diagnosis: A case of ilio-iliac arteriovenous fistula presenting as decompensated heart failure LessonIn case of high output cardiac failure, an arteriovenous fistula should be considered. High-output heart failure due to ilio-iliac arteriovenous fistula is a rare phenomenon. We describe a cas...
Couples HIV counselling and couple relationships in India, Georgia and the Dominican Republic Background: Couples HIV counseling and testing is essential for combination HIV prevention, but its uptake remains very low. We aimed to evaluate factors associated with couples HIV counseling uptake in India, Georgia and the...
Contrast-induced Acute Kidney Injury Contrast-induced acute kidney injury (CI-AKI) is the third common cause of kidney injury in hospitalized patients. It describes a wide spectrum of kidney injury from mild and reversible to permanent and irreversible. The mechanism of contrast-induced AKI and strategies to prevent i...
Costs of remote monitoring vs. ambulatory follow-ups of implanted cardioverter defibrillators in the randomized ECOST study AimsThe Effectiveness and Cost of ICD follow-up Schedule with Telecardiology (ECOST) trial evaluated prospectively the economic impact of long-term remote monitoring (RM) of implantable cardiover...
Peptide mimetics of immunoglobulin A (IgA) and FcαRI block IgA‐induced human neutrophil activation and migration [fig] Supporting, Figure 1 Supporting, Figure 3: Model of interaction sites of IgA and FcaRI (A) Model of the structure of the complex of two IgA Fc heavy chains, interacting with two extracellular domains...
An Efficient, Counter-Selection-Based Method for Prophage Curing in Pseudomonas aeruginosa Strains Inducible phage extraction LB (2 ml) was inoculated with 39016 strain incubated overnight. On the next day, the bacteria were diluted 1:50 with medium to a final volume of 4 ml and incubated until reaching OD 0.5 at 595n...
The effect of music on simulated surgical performance: a systematic review Introduction Beneficial effects of music have been described on several cognitive domains, task performance, stress, anxiety and pain. Greater surgical skill is a factor that has been associated with improved patient outcome. The aim of this sy...
Association of education level with diabetes prevalence in Latin American cities and its modification by city social environment Background Diabetes prevalence continues to increase in urban areas of low-income and middle-income countries (LMIC). Evidence from high-income countries suggests an inverse association betw...
The association of smoking and socioeconomic status on cutaneous melanoma: a population‐based, data‐linkage, case–control study† Background Previous studies have identified an inverse association between melanoma and smoking; however, data from population-based studies are scarce. Objectives To determine the associati...
Metabolic disorders and the risk of head and neck cancer: a protocol for a systematic review and meta-analysis # Introduction Head and neck cancer squamous cell carcinoma (HNSCC), which includes cancer of the oral cavity, oropharynx, hypopharynx and larynx, is the world's sixth most common cancer, with the highest i...
Resistance to organic hydroperoxides requires ohr and ohrR genes in Sinorhizobium meliloti Background: Sinorhizobium meliloti is a symbiotic nitrogen-fixing bacterium that elicits nodules on roots of host plants Medicago sativa. During nodule formation bacteria have to withstand oxygen radicals produced by the plant. ...
Calcium pyrophosphate deposition disease of the temporomandibular joint invading the middle cranial fossa: Two case reports # Introduction Tophaceous pseudogout, also known as calcium pyrophosphate deposition disease (CPPD), is a recurrent acute attack of arthritis caused by calcium pyrophosphate dihydrate crystals ...
Epithelial-Myoepithelial Carcinoma of the Base of Tongue with Possible Lung Metastases Background. Epithelial-myoepithelial carcinomas are rare neoplasms usually arising from the salivary glands. There is limited evidence in the literature on their prognosis in the base of the tongue but other cases have resolved with...
The annual costs of cardiovascular diseases and mental disorders attributable to job strain in France Background: Work stress has become a major occupational risk factor in industrialized countries and an important economic issue. The objective was to estimate the annual costs of coronary heart diseases (CHD) and ment...
18F-Fluorocholine uptake matching CT lesions in the lungs of a patient clinically cured from COVID-19 syndrome F-Fluorocholine uptake matching CT lesions in the lungs of a patient clinically cured from COVID-19 syndromeF-Fluorocholine uptake matching CT lesions in the lungs of a patient clinically cured from COVID-19 ...
Cognitive decline due to excess synaptic Zn2+ signaling in the hippocampus Zinc is an essential component of physiological brain function. Vesicular zinc is released from glutamatergic (zincergic) neuron terminals and serves as a signal factor (Zn 2+ signal) in both the intracellular (cytosol) compartment and the extr...
A new-onset pulmonary artery stenosis in a young man: case report # Introduction Pulmonary artery sarcoma is a rare type of malignant vascular tumour characterized by a very aggressive clinical course and an unfavourable prognosis.Its rarity and the absence of specific symptoms, especially at the onset, make the dia...
Laparoscopic Colorectal Resection in Octogenarian Patients The population older than 80 years has been increasing. A significant proportion of colorectal diseases that require colorectal resection occur in very elderly patients. However, the benefits of laparoscopy remain controversial in octogenarians. A systematic r...
The spectrum of genetic variants and phenotypic features of Southeast Asian patients with Noonan syndrome Background: Noonan syndrome (NS) is an autosomal dominant disorder that belongs to a group of developmental disorders called RASopathies with overlapping features and multiple causative genes. The aim of the study...
Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis [bib_ref] A 2015 update on predictive molecular pathology and its role in targeted..., Dietel [/bib_ref] [bib_ref] Insulitis and b-cell mass in the natural history of type 1 diabetes, Campbell-Thompson [/bib_ref] ## Pathophysiology of di...
Engaging community pharmacists to eliminate inadvertent doping in sports: A study of their knowledge on doping This study aimed to evaluate the community pharmacists' knowledge of tackling the issue of inadvertent doping in Malaysia. A cross-sectional survey was conducted among 384 community pharmacists working in Mal...
Exploring experiences and needs of spousal carers of people with behavioural variant frontotemporal dementia (bvFTD) including those with familial FTD (fFTD): a qualitative study Introduction: Carers of people with frontotemporal dementia (FTD) experience greater challenges than carers of people with other dementias d...
Complementary feeding practices, dietary diversity, and nutrient composition of complementary foods of children 6–24 months old in Jimma Zone, Southwest Ethiopia Background: Mothers and caregivers typically feed infants according to their culture, purchase power and level of awareness with no due diligence to nutritio...
Pregnancy through Assisted Reproductive Technology in a Patient with Thoracic Endometriosis Syndrome [fig_ref] Figure 2: Computed tomography chest [/fig_ref] [bib_ref] Bronchobiliary fistula: A rare complication of hepatic endometriosis, Schuld [/bib_ref] [bib_ref] Synchronous rectovaginal, urinary bladder, and pulmo...
Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates Microbial natural products exhibit immense structural diversity and complexity and have captured the attention of researchers for several decades. They have been explored for a wide spectrum...
Phosphate‐induced resistance to pathogen infection in Arabidopsis In nature, plants are concurrently exposed to a number of abiotic and biotic stresses. Our understanding of convergence points between responses to combined biotic/abiotic stress pathways remains, however, rudimentary. Here we show that MIR399 overexpre...
Strategies for in vitro engineering of the translation machinery Engineering the process of molecular translation, or protein biosynthesis, has emerged as a major opportunity in synthetic and chemical biology to generate novel biological insights and enable new applications (e.g. designer protein therapeutics). Here, ...