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10
What was the administration route of drug 'IDARUCIZUMAB'?
Idarucizumab for dabigatran reversal in cardiac tamponade complicating percutaneous intervention in ST elevation myocardial infarction. An 83-year-old man with a history of permanent atrial fibrillation (AF) anticoagulated by dabigatran 150 b.i.d., type 2 diabetes mellitus, and hypertension was admitted to the hospital...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY-NC-SA
33868433
19,209,253
2021-03
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Breast cancer metastatic'.
Olaparib in hormone receptor-positive, HER2-negative metastatic breast cancer with a somatic BRCA2 mutation. The oral poly(adenosine diphosphate-ribose) polymerase inhibitor olaparib is approved for the treatment of patients with human epidermal growth factor 2-negative (HER2-) metastatic breast cancer (mBC) and a germ...
CARBOPLATIN
DrugsGivenReaction
CC BY-NC
33868464
19,272,470
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Malignant neoplasm progression'.
Olaparib in hormone receptor-positive, HER2-negative metastatic breast cancer with a somatic BRCA2 mutation. The oral poly(adenosine diphosphate-ribose) polymerase inhibitor olaparib is approved for the treatment of patients with human epidermal growth factor 2-negative (HER2-) metastatic breast cancer (mBC) and a germ...
CARBOPLATIN
DrugsGivenReaction
CC BY-NC
33868464
19,272,470
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Palmar-plantar erythrodysaesthesia syndrome'.
Olaparib in hormone receptor-positive, HER2-negative metastatic breast cancer with a somatic BRCA2 mutation. The oral poly(adenosine diphosphate-ribose) polymerase inhibitor olaparib is approved for the treatment of patients with human epidermal growth factor 2-negative (HER2-) metastatic breast cancer (mBC) and a germ...
CAPECITABINE
DrugsGivenReaction
CC BY-NC
33868464
20,984,681
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Product use in unapproved indication'.
Olaparib in hormone receptor-positive, HER2-negative metastatic breast cancer with a somatic BRCA2 mutation. The oral poly(adenosine diphosphate-ribose) polymerase inhibitor olaparib is approved for the treatment of patients with human epidermal growth factor 2-negative (HER2-) metastatic breast cancer (mBC) and a germ...
CARBOPLATIN
DrugsGivenReaction
CC BY-NC
33868464
19,272,470
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Product use in unapproved indication'.
Yttrium-90 radioembolization in desmoplastic small round cell tumor with recurrent hepatic metastasis following hyperthermic intraperitoneal chemotherapy. We report a case of a 26-year-old male who was diagnosed with metastatic desmoplastic small round cell tumor initially treated with systemic chemotherapy followed by...
TEMOZOLOMIDE, VINCRISTINE
DrugsGivenReaction
CC BY-NC-ND
33868532
19,175,731
2021-06
What was the dosage of drug 'TEMOZOLOMIDE'?
Yttrium-90 radioembolization in desmoplastic small round cell tumor with recurrent hepatic metastasis following hyperthermic intraperitoneal chemotherapy. We report a case of a 26-year-old male who was diagnosed with metastatic desmoplastic small round cell tumor initially treated with systemic chemotherapy followed by...
1 CYCLE
DrugDosageText
CC BY-NC-ND
33868532
19,175,731
2021-06
What was the dosage of drug 'VINCRISTINE'?
Yttrium-90 radioembolization in desmoplastic small round cell tumor with recurrent hepatic metastasis following hyperthermic intraperitoneal chemotherapy. We report a case of a 26-year-old male who was diagnosed with metastatic desmoplastic small round cell tumor initially treated with systemic chemotherapy followed by...
1 CYCLE
DrugDosageText
CC BY-NC-ND
33868532
19,175,731
2021-06
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Disease progression'.
A case of hyperprogressive disease following atezolizumab therapy for pulmonary pleomorphic carcinoma with epidermal growth factor receptor mutation. A 66-year old man with non-smoking history was diagnosed with pulmonary pleomorphic carcinoma of the right lower lobe. The carcinoma metastasized to the brain, lungs, ple...
CARBOPLATIN, PEMETREXED
DrugsGivenReaction
CC BY-NC-ND
33868915
19,321,757
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Therapeutic product effect incomplete'.
A case of hyperprogressive disease following atezolizumab therapy for pulmonary pleomorphic carcinoma with epidermal growth factor receptor mutation. A 66-year old man with non-smoking history was diagnosed with pulmonary pleomorphic carcinoma of the right lower lobe. The carcinoma metastasized to the brain, lungs, ple...
CARBOPLATIN, PEMETREXED
DrugsGivenReaction
CC BY-NC-ND
33868915
19,321,757
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Malignant neoplasm progression'.
Adenocarcinoma of the urethra: A rare subtype of urethral cancer. Urethral adenocarcinoma (UA) is a rare type of urethral cancer with a poor prognosis. We present a case of UA of intestinal subtype in a 57-year-old patient who initially had lower urinary tract symptoms and was subsequently found to have a urethral lesi...
CAPECITABINE, FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN
DrugsGivenReaction
CC BY-NC-ND
33868934
19,656,564
2021-07
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Therapeutic product effect incomplete'.
Adenocarcinoma of the urethra: A rare subtype of urethral cancer. Urethral adenocarcinoma (UA) is a rare type of urethral cancer with a poor prognosis. We present a case of UA of intestinal subtype in a 57-year-old patient who initially had lower urinary tract symptoms and was subsequently found to have a urethral lesi...
CAPECITABINE, FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN
DrugsGivenReaction
CC BY-NC-ND
33868934
19,656,564
2021-07
What was the outcome of reaction 'Malignant neoplasm progression'?
Adenocarcinoma of the urethra: A rare subtype of urethral cancer. Urethral adenocarcinoma (UA) is a rare type of urethral cancer with a poor prognosis. We present a case of UA of intestinal subtype in a 57-year-old patient who initially had lower urinary tract symptoms and was subsequently found to have a urethral lesi...
Fatal
ReactionOutcome
CC BY-NC-ND
33868934
19,656,564
2021-07
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Acidosis'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,214,506
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Acute kidney injury'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,214,506
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Analgesic drug level increased'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,214,506
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Continuous haemodiafiltration'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,254,919
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Death'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,254,919
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Depressed level of consciousness'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,262,187
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Diffuse axonal injury'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,262,187
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Endotracheal intubation'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,254,919
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Haemodialysis'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,254,919
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hepatic failure'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,254,919
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Ileus'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,262,187
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Intentional overdose'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,214,506
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Renal replacement therapy'.
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
ACETAMINOPHEN, GABAPENTIN, MORPHINE
DrugsGivenReaction
CC BY
33868959
19,254,919
2021
What was the administration route of drug 'ACETAMINOPHEN'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Oral
DrugAdministrationRoute
CC BY
33868959
19,262,187
2021
What was the administration route of drug 'ACETAMINOPHEN\HYDROCODONE'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Oral
DrugAdministrationRoute
CC BY
33868959
19,183,261
2021
What was the administration route of drug 'GABAPENTIN'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Oral
DrugAdministrationRoute
CC BY
33868959
19,262,187
2021
What was the administration route of drug 'MORPHINE'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Oral
DrugAdministrationRoute
CC BY
33868959
19,262,187
2021
What was the dosage of drug 'ACETAMINOPHEN\HYDROCODONE'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
50 G
DrugDosageText
CC BY
33868959
19,183,261
2021
What was the outcome of reaction 'Acidosis'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,214,506
2021
What was the outcome of reaction 'Acute hepatic failure'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Brain oedema'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Cerebral haemorrhage'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Coagulopathy'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Continuous haemodiafiltration'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,254,919
2021
What was the outcome of reaction 'Death'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,254,919
2021
What was the outcome of reaction 'Depressed level of consciousness'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Diffuse axonal injury'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Endotracheal intubation'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,254,919
2021
What was the outcome of reaction 'Haemodialysis'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,254,919
2021
What was the outcome of reaction 'Hepatic failure'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,254,919
2021
What was the outcome of reaction 'Ileus'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Intentional overdose'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,214,506
2021
What was the outcome of reaction 'Mental status changes'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Metabolic acidosis'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,214,506
2021
What was the outcome of reaction 'Overdose'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
What was the outcome of reaction 'Renal replacement therapy'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,254,919
2021
What was the outcome of reaction 'Toxicity to various agents'?
Massive acetaminophen overdose with metabolic acidosis refractory to N-acetylcysteine, fomepizole, and renal replacement therapy. Massive Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common presentation to emergency departments around the world. While N-acetylcysteine (NAC) remains the cornerstone of trea...
Fatal
ReactionOutcome
CC BY
33868959
19,262,187
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Disease progression'.
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
GEMCITABINE
DrugsGivenReaction
CC BY
33869037
19,264,165
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Skin ulcer'.
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
GEMCITABINE\GEMCITABINE HYDROCHLORIDE
DrugsGivenReaction
CC BY
33869037
19,222,662
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Therapeutic product effect incomplete'.
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
GEMCITABINE
DrugsGivenReaction
CC BY
33869037
19,264,165
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Vasculitis'.
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
GEMCITABINE\GEMCITABINE HYDROCHLORIDE
DrugsGivenReaction
CC BY
33869037
19,222,662
2021
What was the administration route of drug 'GEMCITABINE'?
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
33869037
19,264,165
2021
What was the administration route of drug 'PEMETREXED'?
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
Other
DrugAdministrationRoute
CC BY
33869037
19,351,405
2021
What was the dosage of drug 'CISPLATIN'?
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
6 CYCLES
DrugDosageText
CC BY
33869037
19,351,405
2021
What was the dosage of drug 'GEMCITABINE HYDROCHLORIDE'?
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
UNK, CYCLIC
DrugDosageText
CC BY
33869037
19,245,962
2021
What was the outcome of reaction 'Skin ulcer'?
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
Not recovered
ReactionOutcome
CC BY
33869037
19,222,662
2021
What was the outcome of reaction 'Vasculitis'?
Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases. Pemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However,...
Not recovered
ReactionOutcome
CC BY
33869037
19,222,662
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Bronchial hyperreactivity'.
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years. Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce. Based on an ...
CEFTAZIDIME, CIPROFLOXACIN, COLISTIN SULFATE, FLUCLOXACILLIN, TOBRAMYCIN
DrugsGivenReaction
CC BY
33869120
19,648,646
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Pathogen resistance'.
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years. Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce. Based on an ...
CEFTAZIDIME, CIPROFLOXACIN, COLISTIN SULFATE, FLUCLOXACILLIN, TOBRAMYCIN
DrugsGivenReaction
CC BY
33869120
19,623,920
2021
What was the administration route of drug 'CEFTAZIDIME'?
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years. Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce. Based on an ...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
33869120
19,648,646
2021
What was the administration route of drug 'COLISTIN SULFATE'?
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years. Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce. Based on an ...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
33869120
19,648,646
2021
What was the administration route of drug 'FLUCLOXACILLIN'?
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years. Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce. Based on an ...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
33869120
19,648,646
2021
What was the administration route of drug 'TOBRAMYCIN'?
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years. Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce. Based on an ...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
33869120
19,648,646
2021
What was the dosage of drug 'COLISTIN SULFATE'?
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years. Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce. Based on an ...
NEBULISED
DrugDosageText
CC BY
33869120
19,623,920
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug resistance'.
Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection. Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutan...
ERTAPENEM
DrugsGivenReaction
CC BY
33869238
20,990,378
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Off label use'.
Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection. Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutan...
CILASTATIN SODIUM\IMIPENEM, CIPROFLOXACIN, ERTAPENEM, FLUCONAZOLE, SODIUM CHLORIDE
DrugsGivenReaction
CC BY
33869238
19,459,985
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Pathogen resistance'.
Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection. Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutan...
CILASTATIN SODIUM\IMIPENEM, CIPROFLOXACIN, ERTAPENEM, FLUCONAZOLE, SODIUM CHLORIDE
DrugsGivenReaction
CC BY
33869238
19,459,985
2021
What is the weight of the patient?
Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection. Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutan...
74 kg.
Weight
CC BY
33869238
20,990,378
2021
What was the administration route of drug 'CILASTATIN SODIUM\IMIPENEM'?
Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection. Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutan...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
33869238
19,459,985
2021
What was the administration route of drug 'CIPROFLOXACIN'?
Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection. Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutan...
Oral
DrugAdministrationRoute
CC BY
33869238
19,459,985
2021
What was the administration route of drug 'FLUCONAZOLE'?
Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection. Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutan...
Oral
DrugAdministrationRoute
CC BY
33869238
19,459,985
2021
What was the dosage of drug 'SODIUM CHLORIDE'?
Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection. Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutan...
50 MILLILITER
DrugDosageText
CC BY
33869238
19,459,985
2021
What was the administration route of drug 'AMINOSALICYLIC ACID'?
Prolonged use of bedaquiline in two patients with pulmonary extensively drug-resistant tuberculosis: Two case reports. BACKGROUND Bedaquiline is among the prioritized drugs recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis (XDR-TB). Many patients have not achieved...
Oral
DrugAdministrationRoute
CC BY-NC
33869610
20,736,074
2021-04-06
What was the administration route of drug 'CAPREOMYCIN'?
Prolonged use of bedaquiline in two patients with pulmonary extensively drug-resistant tuberculosis: Two case reports. BACKGROUND Bedaquiline is among the prioritized drugs recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis (XDR-TB). Many patients have not achieved...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY-NC
33869610
20,736,074
2021-04-06
What was the administration route of drug 'ISONIAZID'?
Prolonged use of bedaquiline in two patients with pulmonary extensively drug-resistant tuberculosis: Two case reports. BACKGROUND Bedaquiline is among the prioritized drugs recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis (XDR-TB). Many patients have not achieved...
Oral
DrugAdministrationRoute
CC BY-NC
33869610
20,737,539
2021-04-06
What was the administration route of drug 'PROTIONAMIDE'?
Prolonged use of bedaquiline in two patients with pulmonary extensively drug-resistant tuberculosis: Two case reports. BACKGROUND Bedaquiline is among the prioritized drugs recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis (XDR-TB). Many patients have not achieved...
Oral
DrugAdministrationRoute
CC BY-NC
33869610
20,736,074
2021-04-06
What was the administration route of drug 'PYRAZINAMIDE'?
Prolonged use of bedaquiline in two patients with pulmonary extensively drug-resistant tuberculosis: Two case reports. BACKGROUND Bedaquiline is among the prioritized drugs recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis (XDR-TB). Many patients have not achieved...
Oral
DrugAdministrationRoute
CC BY-NC
33869610
20,736,074
2021-04-06
What was the administration route of drug 'RIFAMPIN'?
Prolonged use of bedaquiline in two patients with pulmonary extensively drug-resistant tuberculosis: Two case reports. BACKGROUND Bedaquiline is among the prioritized drugs recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis (XDR-TB). Many patients have not achieved...
Oral
DrugAdministrationRoute
CC BY-NC
33869610
20,961,425
2021-04-06
What was the dosage of drug 'ETHAMBUTOL HYDROCHLORIDE'?
Prolonged use of bedaquiline in two patients with pulmonary extensively drug-resistant tuberculosis: Two case reports. BACKGROUND Bedaquiline is among the prioritized drugs recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis (XDR-TB). Many patients have not achieved...
750 MG/D, Q.D., P.O.
DrugDosageText
CC BY-NC
33869610
20,965,121
2021-04-06
What was the dosage of drug 'LEVOFLOXACIN'?
Prolonged use of bedaquiline in two patients with pulmonary extensively drug-resistant tuberculosis: Two case reports. BACKGROUND Bedaquiline is among the prioritized drugs recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis (XDR-TB). Many patients have not achieved...
500 MG, QD, PO
DrugDosageText
CC BY-NC
33869610
20,965,121
2021-04-06
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Acute hepatic failure'.
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
METHIMAZOLE, WARFARIN
DrugsGivenReaction
CC BY
33869649
20,911,598
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Cerebral atrophy'.
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
METHIMAZOLE, WARFARIN
DrugsGivenReaction
CC BY
33869649
20,911,598
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Coagulopathy'.
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
METHIMAZOLE, WARFARIN
DrugsGivenReaction
CC BY
33869649
20,911,598
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Congestive hepatopathy'.
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
METHIMAZOLE, WARFARIN
DrugsGivenReaction
CC BY
33869649
20,911,598
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug ineffective'.
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
METHIMAZOLE, WARFARIN
DrugsGivenReaction
CC BY
33869649
20,911,598
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug-induced liver injury'.
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
METHIMAZOLE, WARFARIN
DrugsGivenReaction
CC BY
33869649
20,911,598
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Encephalopathy'.
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
METHIMAZOLE, WARFARIN
DrugsGivenReaction
CC BY
33869649
20,911,598
2021-04
What was the dosage of drug 'METHIMAZOLE'?
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
UNK (RESTARTED)
DrugDosageText
CC BY
33869649
20,911,598
2021-04
What was the outcome of reaction 'Acute hepatic failure'?
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
Recovering
ReactionOutcome
CC BY
33869649
20,911,598
2021-04
What was the outcome of reaction 'Cerebral atrophy'?
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
Recovering
ReactionOutcome
CC BY
33869649
20,911,598
2021-04
What was the outcome of reaction 'Coagulopathy'?
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
Recovering
ReactionOutcome
CC BY
33869649
20,911,598
2021-04
What was the outcome of reaction 'Congestive hepatopathy'?
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
Recovering
ReactionOutcome
CC BY
33869649
20,911,598
2021-04
What was the outcome of reaction 'Drug-induced liver injury'?
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
Recovering
ReactionOutcome
CC BY
33869649
20,911,598
2021-04
What was the outcome of reaction 'Encephalopathy'?
Thyroid Disease-Induced Hepatic Dysfunction: A Clinical Puzzle. The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucid...
Recovering
ReactionOutcome
CC BY
33869649
20,911,598
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Cardiopulmonary failure'.
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
ALBUMIN HUMAN, CAMRELIZUMAB, CAPECITABINE, CASPOFUNGIN, CEFOPERAZONE\SULBACTAM, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, URSODIOL
DrugsGivenReaction
CC BY
33869777
19,555,242
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug ineffective'.
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
ALBUMIN HUMAN, CAMRELIZUMAB, CAPECITABINE, CASPOFUNGIN, CEFOPERAZONE\SULBACTAM, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, URSODIOL
DrugsGivenReaction
CC BY
33869777
19,555,242
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hepatic failure'.
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
ALBUMIN HUMAN, CAMRELIZUMAB, CAPECITABINE, CASPOFUNGIN, CEFOPERAZONE\SULBACTAM, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, URSODIOL
DrugsGivenReaction
CC BY
33869777
19,555,242
2021