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10
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Multiple organ dysfunction syndrome'.
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
ALBUMIN HUMAN, CAMRELIZUMAB, CAPECITABINE, CASPOFUNGIN, CEFOPERAZONE\SULBACTAM, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, URSODIOL
DrugsGivenReaction
CC BY
33869777
19,555,242
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Opportunistic infection'.
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
ALBUMIN HUMAN, CAMRELIZUMAB, CAPECITABINE, CASPOFUNGIN, CEFOPERAZONE\SULBACTAM, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, URSODIOL
DrugsGivenReaction
CC BY
33869777
19,555,242
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Sepsis'.
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
ALBUMIN HUMAN, CAMRELIZUMAB, CAPECITABINE, CASPOFUNGIN, CEFOPERAZONE\SULBACTAM, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, URSODIOL
DrugsGivenReaction
CC BY
33869777
19,555,242
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Septic shock'.
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
ALBUMIN HUMAN, CAMRELIZUMAB, CAPECITABINE, CASPOFUNGIN, CEFOPERAZONE\SULBACTAM, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, URSODIOL
DrugsGivenReaction
CC BY
33869777
19,555,242
2021
What was the dosage of drug 'ALBUMIN HUMAN'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
0.5?1.0 GRAM PER DAY
DrugDosageText
CC BY
33869777
19,555,242
2021
What was the dosage of drug 'CAMRELIZUMAB'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
200 MILLIGRAM, EVERY 2 WEEKS
DrugDosageText
CC BY
33869777
19,555,242
2021
What was the dosage of drug 'CASPOFUNGIN'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
50 MILLIGRAM
DrugDosageText
CC BY
33869777
19,555,242
2021
What was the dosage of drug 'CEFOPERAZONE\SULBACTAM'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
2 GRAM, EVERY 12 HRS
DrugDosageText
CC BY
33869777
19,555,242
2021
What was the dosage of drug 'URSODIOL'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
25 MILLIGRAM/KILOGRAM PER DAY
DrugDosageText
CC BY
33869777
19,555,242
2021
What was the outcome of reaction 'Cardiopulmonary failure'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
Fatal
ReactionOutcome
CC BY
33869777
19,555,242
2021
What was the outcome of reaction 'Hepatic failure'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
Fatal
ReactionOutcome
CC BY
33869777
19,555,242
2021
What was the outcome of reaction 'Multiple organ dysfunction syndrome'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
Fatal
ReactionOutcome
CC BY
33869777
19,555,242
2021
What was the outcome of reaction 'Opportunistic infection'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
Fatal
ReactionOutcome
CC BY
33869777
19,555,242
2021
What was the outcome of reaction 'Sepsis'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
Fatal
ReactionOutcome
CC BY
33869777
19,555,242
2021
What was the outcome of reaction 'Septic shock'?
Fatal immune-related hepatitis with intrahepatic cholestasis and pneumonia associated with camrelizumab: A case report and literature review. Camrelizumab (SHR-1210), a human monoclonal antibody against programmed death receptor 1 (PD-1), blocks the binding of PD-1 to PD-L1, consequently inhibiting immune system evasio...
Fatal
ReactionOutcome
CC BY
33869777
19,555,242
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Cutaneous nocardiosis'.
Clinical analysis of 11 cases of nocardiosis. Nocardiosis is a rare, life-threatening, opportunistic, and suppurative infection. Its clinical manifestation lacks specificity, which makes early diagnosis difficult. A retrospective analysis of the clinical records of 11 patients with nocardiosis admitted to our hospital ...
HYDROXYCHLOROQUINE, METHOTREXATE, PREDNISONE
DrugsGivenReaction
CC BY
33869782
19,812,295
2021
What was the outcome of reaction 'Cutaneous nocardiosis'?
Clinical analysis of 11 cases of nocardiosis. Nocardiosis is a rare, life-threatening, opportunistic, and suppurative infection. Its clinical manifestation lacks specificity, which makes early diagnosis difficult. A retrospective analysis of the clinical records of 11 patients with nocardiosis admitted to our hospital ...
Recovering
ReactionOutcome
CC BY
33869782
19,812,295
2021
What was the outcome of reaction 'Nocardiosis'?
Clinical analysis of 11 cases of nocardiosis. Nocardiosis is a rare, life-threatening, opportunistic, and suppurative infection. Its clinical manifestation lacks specificity, which makes early diagnosis difficult. A retrospective analysis of the clinical records of 11 patients with nocardiosis admitted to our hospital ...
Recovering
ReactionOutcome
CC BY
33869782
19,811,204
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Musculoskeletal stiffness'.
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
ASFOTASE ALFA
DrugsGivenReaction
CC BY
33869986
18,620,835
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Neck pain'.
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
ASFOTASE ALFA
DrugsGivenReaction
CC BY
33869986
18,620,835
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Pyramidal tract syndrome'.
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
ASFOTASE ALFA
DrugsGivenReaction
CC BY
33869986
18,620,835
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Spinal cord compression'.
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
ASFOTASE ALFA
DrugsGivenReaction
CC BY
33869986
18,620,835
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Spinal ligament ossification'.
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
ASFOTASE ALFA
DrugsGivenReaction
CC BY
33869986
18,620,835
2021-04
What is the weight of the patient?
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
78 kg.
Weight
CC BY
33869986
18,620,835
2021-04
What was the outcome of reaction 'Musculoskeletal stiffness'?
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
Recovering
ReactionOutcome
CC BY
33869986
18,620,835
2021-04
What was the outcome of reaction 'Neck pain'?
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
Recovering
ReactionOutcome
CC BY
33869986
18,620,835
2021-04
What was the outcome of reaction 'Pyramidal tract syndrome'?
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
Recovering
ReactionOutcome
CC BY
33869986
18,620,835
2021-04
What was the outcome of reaction 'Spinal cord compression'?
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
Recovering
ReactionOutcome
CC BY
33869986
18,620,835
2021-04
What was the outcome of reaction 'Spinal ligament ossification'?
Hypophosphatasia: A Case of Two Patients With Spinal Cord Compression From Increase in Ligamentous Ossifications During Treatment. Treatment with asfotase alfa has transformed the prognosis of hypophosphatasia in children and improves the bone and muscle signs in adults. The doses used in adults are the same as in chil...
Recovering
ReactionOutcome
CC BY
33869986
18,620,835
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Exostosis'.
Antiresorptive treatment and talar collapse after displaced fractures of the talar neck: a long-term follow-up of 19 patients. Background and purpose - Displaced fractures of the talar neck are associated with a high risk of structural collapse. In this observational analysis we hypothesized that pharmacological inhibi...
DENOSUMAB
DrugsGivenReaction
CC BY
33870825
19,210,918
2021-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Incorrect route of product administration'.
Antiresorptive treatment and talar collapse after displaced fractures of the talar neck: a long-term follow-up of 19 patients. Background and purpose - Displaced fractures of the talar neck are associated with a high risk of structural collapse. In this observational analysis we hypothesized that pharmacological inhibi...
DENOSUMAB
DrugsGivenReaction
CC BY
33870825
19,210,918
2021-08
What was the administration route of drug 'DENOSUMAB'?
Antiresorptive treatment and talar collapse after displaced fractures of the talar neck: a long-term follow-up of 19 patients. Background and purpose - Displaced fractures of the talar neck are associated with a high risk of structural collapse. In this observational analysis we hypothesized that pharmacological inhibi...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
33870825
19,210,918
2021-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Abdominal pain upper'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Agitation'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Anxiety'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Diarrhoea'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hyperhidrosis'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Insomnia'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Lacrimation increased'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Restlessness'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Rhinorrhoea'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Withdrawal syndrome'.
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
METHADONE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC-ND
33870954
20,908,986
2021-04-14
What was the administration route of drug 'METHADONE HYDROCHLORIDE'?
Clinical Case Conference: Strategies for Transferring from Methadone to Buprenorphine. The mainstay of treatment for opioid use disorder are medications, methadone (a full opioid agonist), or buprenorphine (a partial opioid agonist), in conjunction with psychosocial interventions. Both treatments are effective but safe...
Oral
DrugAdministrationRoute
CC BY-NC-ND
33870954
20,908,986
2021-04-14
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Acute kidney injury'.
Primary central nervous system Hodgkin's lymphoma: a case report. Primary central nervous system Hodgkin's lymphoma (CNS-HL) is extremely rare. This current case report describes a 60-year-old male patient that presented with numbness of the left lower extremity and worsening headache. After a full range of investigati...
CYTARABINE, METHOTREXATE
DrugsGivenReaction
CC BY-NC
33874776
19,398,136
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Nephropathy toxic'.
Primary central nervous system Hodgkin's lymphoma: a case report. Primary central nervous system Hodgkin's lymphoma (CNS-HL) is extremely rare. This current case report describes a 60-year-old male patient that presented with numbness of the left lower extremity and worsening headache. After a full range of investigati...
CYTARABINE, METHOTREXATE
DrugsGivenReaction
CC BY-NC
33874776
19,398,136
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Off label use'.
Primary central nervous system Hodgkin's lymphoma: a case report. Primary central nervous system Hodgkin's lymphoma (CNS-HL) is extremely rare. This current case report describes a 60-year-old male patient that presented with numbness of the left lower extremity and worsening headache. After a full range of investigati...
CYTARABINE, METHOTREXATE
DrugsGivenReaction
CC BY-NC
33874776
19,398,136
2021-04
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Renal impairment'.
Primary central nervous system Hodgkin's lymphoma: a case report. Primary central nervous system Hodgkin's lymphoma (CNS-HL) is extremely rare. This current case report describes a 60-year-old male patient that presented with numbness of the left lower extremity and worsening headache. After a full range of investigati...
CYTARABINE, DEXAMETHASONE, METHOTREXATE
DrugsGivenReaction
CC BY-NC
33874776
19,352,064
2021-04
What was the administration route of drug 'CYTARABINE'?
Primary central nervous system Hodgkin's lymphoma: a case report. Primary central nervous system Hodgkin's lymphoma (CNS-HL) is extremely rare. This current case report describes a 60-year-old male patient that presented with numbness of the left lower extremity and worsening headache. After a full range of investigati...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY-NC
33874776
19,352,064
2021-04
What was the administration route of drug 'METHOTREXATE'?
Primary central nervous system Hodgkin's lymphoma: a case report. Primary central nervous system Hodgkin's lymphoma (CNS-HL) is extremely rare. This current case report describes a 60-year-old male patient that presented with numbness of the left lower extremity and worsening headache. After a full range of investigati...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY-NC
33874776
19,352,064
2021-04
What was the dosage of drug 'DEXAMETHASONE'?
Primary central nervous system Hodgkin's lymphoma: a case report. Primary central nervous system Hodgkin's lymphoma (CNS-HL) is extremely rare. This current case report describes a 60-year-old male patient that presented with numbness of the left lower extremity and worsening headache. After a full range of investigati...
5 mg (milligrams).
DrugDosage
CC BY-NC
33874776
19,352,064
2021-04
What was the outcome of reaction 'Metastatic malignant melanoma'?
Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma. While programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) antagonists have improved the prognosis for many patients with melanoma, around 60% fail therapy. PVSRIPO is a non-neurovirulent rhinovir...
Fatal
ReactionOutcome
CC BY-NC
33875611
19,461,356
2021-04
What was the outcome of reaction 'Stress cardiomyopathy'?
Primary Takotsubo Syndrome as a Complication of Bladder Cancer Treatment in a 62-Year-Old Woman. BACKGROUND The main causes for takotsubo syndrome (TS) in oncological patients are stress related to cancer diagnosis and treatment, pain in the course of the disease, treatment complications, and paraneoplastic syndromes. ...
Recovering
ReactionOutcome
CC BY-NC-ND
33875632
19,232,215
2021-04-20
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Cachexia'.
Altered Spectrum of Lymphoid Neoplasms in a Single-Center Cohort of Common Variable Immunodeficiency with Immune Dysregulation. Common variable immune deficiency (CVID) confers an increased risk of lymphoid neoplasms, but reports describing the precise WHO specification of the lymphoma subtypes and their immunological ...
CORTICOSTEROID NOS, HYDROXYCHLOROQUINE, LEFLUNOMIDE, SULFASALAZINE
DrugsGivenReaction
CC BY
33876323
20,126,548
2021-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Diarrhoea'.
Altered Spectrum of Lymphoid Neoplasms in a Single-Center Cohort of Common Variable Immunodeficiency with Immune Dysregulation. Common variable immune deficiency (CVID) confers an increased risk of lymphoid neoplasms, but reports describing the precise WHO specification of the lymphoma subtypes and their immunological ...
CORTICOSTEROID NOS, HYDROXYCHLOROQUINE, LEFLUNOMIDE, SULFASALAZINE
DrugsGivenReaction
CC BY
33876323
20,126,548
2021-08
What was the outcome of reaction 'Anaphylactic reaction'?
Concurrent positive skin tests to prophylactic antibiotics and rocuronium in two patients with life-threatening anaphylaxis after induction of anesthesia. BACKGROUND Prophylactic antibiotics and neuromuscular blocking agents (NMBA) are two of the major causative agents of anaphylaxis after induction of anesthesia. ME...
Recovered
ReactionOutcome
CC BY
33877516
19,898,798
2021-04-20
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Abdominal abscess'.
Targeting EML4-ALK gene fusion variant 3 in thyroid cancer. Finding targetable gene fusions can expand the limited treatment options in radioactive iodine-refractory (RAI-r) thyroid cancer. To that end, we established a novel cell line 'JVE404' derived from an advanced RAI-r papillary thyroid cancer (PTC) patient, harb...
LENVATINIB
DrugsGivenReaction
CC BY
33878728
19,219,868
2021-05-11
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Acquired diaphragmatic eventration'.
Targeting EML4-ALK gene fusion variant 3 in thyroid cancer. Finding targetable gene fusions can expand the limited treatment options in radioactive iodine-refractory (RAI-r) thyroid cancer. To that end, we established a novel cell line 'JVE404' derived from an advanced RAI-r papillary thyroid cancer (PTC) patient, harb...
LENVATINIB
DrugsGivenReaction
CC BY
33878728
19,218,870
2021-05-11
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Cholecystitis acute'.
Targeting EML4-ALK gene fusion variant 3 in thyroid cancer. Finding targetable gene fusions can expand the limited treatment options in radioactive iodine-refractory (RAI-r) thyroid cancer. To that end, we established a novel cell line 'JVE404' derived from an advanced RAI-r papillary thyroid cancer (PTC) patient, harb...
LENVATINIB
DrugsGivenReaction
CC BY
33878728
19,219,868
2021-05-11
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Intestinal perforation'.
Targeting EML4-ALK gene fusion variant 3 in thyroid cancer. Finding targetable gene fusions can expand the limited treatment options in radioactive iodine-refractory (RAI-r) thyroid cancer. To that end, we established a novel cell line 'JVE404' derived from an advanced RAI-r papillary thyroid cancer (PTC) patient, harb...
LENVATINIB
DrugsGivenReaction
CC BY
33878728
19,219,868
2021-05-11
What was the administration route of drug 'LENVATINIB'?
Targeting EML4-ALK gene fusion variant 3 in thyroid cancer. Finding targetable gene fusions can expand the limited treatment options in radioactive iodine-refractory (RAI-r) thyroid cancer. To that end, we established a novel cell line 'JVE404' derived from an advanced RAI-r papillary thyroid cancer (PTC) patient, harb...
Oral
DrugAdministrationRoute
CC BY
33878728
19,219,868
2021-05-11
What was the dosage of drug 'LENVATINIB'?
Targeting EML4-ALK gene fusion variant 3 in thyroid cancer. Finding targetable gene fusions can expand the limited treatment options in radioactive iodine-refractory (RAI-r) thyroid cancer. To that end, we established a novel cell line 'JVE404' derived from an advanced RAI-r papillary thyroid cancer (PTC) patient, harb...
24 mg (milligrams).
DrugDosage
CC BY
33878728
19,219,868
2021-05-11
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug ineffective'.
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation. Preclinical studies and early clinical trials have shown that targeting cancer neoantigens is a promising approach towards the development of personalized cancer immunotherapies. ...
CARBOPLATIN, ETOPOSIDE, LANREOTIDE, PEMBROLIZUMAB
DrugsGivenReaction
CC BY
33879241
20,153,388
2021-04-21
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Condition aggravated'.
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
CLOBETASOL PROPIONATE, DEXAMETHASONE
DrugsGivenReaction
CC BY
33879687
19,871,636
2021-04-23
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug ineffective'.
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
CLOBETASOL PROPIONATE, DEXAMETHASONE
DrugsGivenReaction
CC BY
33879687
19,871,636
2021-04-23
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Malignant neoplasm progression'.
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
CLOBETASOL PROPIONATE, DEXAMETHASONE, FOTEMUSTINE, IPILIMUMAB, NIVOLUMAB
DrugsGivenReaction
CC BY
33879687
19,289,015
2021-04-23
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Morphoea'.
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
IPILIMUMAB, NIVOLUMAB, PEMBROLIZUMAB
DrugsGivenReaction
CC BY
33879687
19,294,772
2021-04-23
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Therapy partial responder'.
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
CLOBETASOL PROPIONATE, DEXAMETHASONE, FOTEMUSTINE, IPILIMUMAB, NIVOLUMAB
DrugsGivenReaction
CC BY
33879687
19,289,015
2021-04-23
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Thyrotoxic crisis'.
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
IPILIMUMAB, NIVOLUMAB, PEMBROLIZUMAB
DrugsGivenReaction
CC BY
33879687
19,294,772
2021-04-23
What was the administration route of drug 'CLOBETASOL PROPIONATE'?
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
Topical
DrugAdministrationRoute
CC BY
33879687
19,871,636
2021-04-23
What was the administration route of drug 'DEXAMETHASONE'?
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
33879687
19,871,636
2021-04-23
What was the dosage of drug 'FOTEMUSTINE'?
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
1.5 CYCLE
DrugDosageText
CC BY
33879687
19,289,015
2021-04-23
What was the dosage of drug 'PEMBROLIZUMAB'?
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
2 MILLIGRAM/KILOGRAM, Q3WK
DrugDosageText
CC BY
33879687
19,294,772
2021-04-23
What was the outcome of reaction 'Condition aggravated'?
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
Not recovered
ReactionOutcome
CC BY
33879687
19,871,636
2021-04-23
What was the outcome of reaction 'Drug ineffective'?
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
Not recovered
ReactionOutcome
CC BY
33879687
19,871,636
2021-04-23
What was the outcome of reaction 'Metastases to central nervous system'?
Generalized morphoea in the setting of combined immune checkpoint inhibitor therapy for metastatic melanoma: A case report. BACKGROUND Immune checkpoint inhibition has dramatically altered the therapeutic landscape in the treatment of a range of locally advanced and metastatic skin cancers. In particular, the treatment...
Not recovered
ReactionOutcome
CC BY
33879687
19,871,636
2021-04-23
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Haemodialysis'.
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
EPINEPHRINE
DrugsGivenReaction
CC BY-NC-ND
33879760
19,209,056
2021-04-21
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hyperhidrosis'.
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
EPINEPHRINE
DrugsGivenReaction
CC BY-NC-ND
33879760
19,209,056
2021-04-21
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Injection site induration'.
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
EPINEPHRINE
DrugsGivenReaction
CC BY-NC-ND
33879760
19,209,056
2021-04-21
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Necrotising fasciitis'.
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
EPINEPHRINE
DrugsGivenReaction
CC BY-NC-ND
33879760
19,209,056
2021-04-21
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Pain in extremity'.
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
EPINEPHRINE
DrugsGivenReaction
CC BY-NC-ND
33879760
19,209,056
2021-04-21
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Tenderness'.
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
EPINEPHRINE
DrugsGivenReaction
CC BY-NC-ND
33879760
19,209,056
2021-04-21
What is the weight of the patient?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
142.9 kg.
Weight
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the administration route of drug 'CLINDAMYCIN'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the administration route of drug 'EPINEPHRINE'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Parenteral
DrugAdministrationRoute
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the administration route of drug 'PIPERACILLIN SODIUM\TAZOBACTAM SODIUM'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the administration route of drug 'VANCOMYCIN'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the dosage of drug 'CLINDAMYCIN'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
900 mg (milligrams).
DrugDosage
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the dosage of drug 'VANCOMYCIN'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
2.5 g (grams).
DrugDosage
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the outcome of reaction 'Acute kidney injury'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovered
ReactionOutcome
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the outcome of reaction 'Clostridial infection'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovering
ReactionOutcome
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the outcome of reaction 'Gas gangrene'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovering
ReactionOutcome
CC BY-NC-ND
33879760
19,320,774
2021-04-21
What was the outcome of reaction 'Haemodialysis'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovered
ReactionOutcome
CC BY-NC-ND
33879760
19,209,056
2021-04-21
What was the outcome of reaction 'Hyperhidrosis'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovered
ReactionOutcome
CC BY-NC-ND
33879760
19,209,056
2021-04-21
What was the outcome of reaction 'Injection site induration'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovered
ReactionOutcome
CC BY-NC-ND
33879760
19,209,056
2021-04-21
What was the outcome of reaction 'Necrotising fasciitis'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovering
ReactionOutcome
CC BY-NC-ND
33879760
19,209,056
2021-04-21
What was the outcome of reaction 'Pain in extremity'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovered
ReactionOutcome
CC BY-NC-ND
33879760
19,209,056
2021-04-21
What was the outcome of reaction 'Tenderness'?
Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg. BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medicat...
Recovered
ReactionOutcome
CC BY-NC-ND
33879760
19,209,056
2021-04-21
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Pneumonia'.
Optimizing Dose-Adjusted EPOCH Chemotherapy with Long-Acting Granulocyte Colony-Stimulating Factor During the COVID-19 Epidemic. Febrile neutropenia (FN) is a highly prevalent complication of chemotherapy. In this study, we aimed to evaluate the efficacy of polyethylene glycol recombinant granulocyte colony-stimulating...
CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, PREDNISONE, VINCRISTINE
DrugsGivenReaction
CC BY-NC
33880064
19,207,681
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Arterial haemorrhage'.
Fatal retroperitoneal hematoma associated with Covid-19 prophylactic anticoagulation protocol. Due to the association between Covid-19 and thromboembolic events, there has been a surge in anticoagulation use during the pandemic based on evolving guidelines for management of hospitalized Covid-19 patients. Spontaneous s...
ASPIRIN, ENOXAPARIN SODIUM, HUMAN RED BLOOD CELL, OXYGEN
DrugsGivenReaction
CC BY
33880136
19,475,255
2021-07
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Coagulopathy'.
Fatal retroperitoneal hematoma associated with Covid-19 prophylactic anticoagulation protocol. Due to the association between Covid-19 and thromboembolic events, there has been a surge in anticoagulation use during the pandemic based on evolving guidelines for management of hospitalized Covid-19 patients. Spontaneous s...
ASPIRIN, ENOXAPARIN SODIUM, HUMAN RED BLOOD CELL, OXYGEN
DrugsGivenReaction
CC BY
33880136
19,475,255
2021-07