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What was the outcome of reaction 'Generalised tonic-clonic seizure'?
Adjunctive use of the ketogenic diet in a young adult with UBE2A deficiency syndrome and super-refractory status epilepticus. The ketogenic diet (KD) may have a role in treating super-refractory status epilepticus (SRSE). Predominantly used in paediatric epilepsy, there are few reports of its use in adults. We describe...
Recovered
ReactionOutcome
CC BY-NC-ND
34095805
20,264,433
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Ductus arteriosus stenosis foetal'.
Foetal ductus arteriosus constriction unrelated to non-steroidal anti-Inflammatory drugs: a case report and literature review. Foetal ductus arteriosus (DA) constriction can be found in complex foetal heart malformations, but rarely as an isolated defect. Although many cases of DA constriction are usually related to No...
FLUOXETINE HYDROCHLORIDE
DrugsGivenReaction
CC BY
34096417
16,369,075
2021-12
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Foetal exposure during pregnancy'.
Foetal ductus arteriosus constriction unrelated to non-steroidal anti-Inflammatory drugs: a case report and literature review. Foetal ductus arteriosus (DA) constriction can be found in complex foetal heart malformations, but rarely as an isolated defect. Although many cases of DA constriction are usually related to No...
FLUOXETINE HYDROCHLORIDE
DrugsGivenReaction
CC BY
34096417
16,369,075
2021-12
What was the administration route of drug 'FLUOXETINE HYDROCHLORIDE'?
Foetal ductus arteriosus constriction unrelated to non-steroidal anti-Inflammatory drugs: a case report and literature review. Foetal ductus arteriosus (DA) constriction can be found in complex foetal heart malformations, but rarely as an isolated defect. Although many cases of DA constriction are usually related to No...
Transplacental
DrugAdministrationRoute
CC BY
34096417
16,369,075
2021-12
What was the outcome of reaction 'Ductus arteriosus stenosis foetal'?
Foetal ductus arteriosus constriction unrelated to non-steroidal anti-Inflammatory drugs: a case report and literature review. Foetal ductus arteriosus (DA) constriction can be found in complex foetal heart malformations, but rarely as an isolated defect. Although many cases of DA constriction are usually related to No...
Recovered
ReactionOutcome
CC BY
34096417
16,369,075
2021-12
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'No adverse event'.
Medication Use in the Management of Comorbidities Among Individuals With Autism Spectrum Disorder From a Large Nationwide Insurance Database. Although there is no pharmacological treatment for autism spectrum disorder (ASD) itself, behavioral and pharmacological therapies have been used to address its symptoms and comm...
ARIPIPRAZOLE
DrugsGivenReaction
CC BY
34097007
19,917,940
2021-09-01
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hepatitis E'.
Severe Hepatitis E virus infection in a patient with rheumatoid arthritis treated with baricitinib. A patient with rheumatoid arthritis (RA) was presented, who developed an infection with the hepatitis E virus (HEV) under treatment with the Janus kinase (JAK) 1 and 2 inhibitor baricitinib. In the 3‑month routine check-...
ATORVASTATIN, FEBUXOSTAT, METHOTREXATE
DrugsGivenReaction
CC BY
34097102
20,631,649
2021-12
What was the dosage of drug 'METHOTREXATE SODIUM'?
Severe Hepatitis E virus infection in a patient with rheumatoid arthritis treated with baricitinib. A patient with rheumatoid arthritis (RA) was presented, who developed an infection with the hepatitis E virus (HEV) under treatment with the Janus kinase (JAK) 1 and 2 inhibitor baricitinib. In the 3‑month routine check-...
DOSES BETWEEN 10 AND 15 MG/WEEK
DrugDosageText
CC BY
34097102
20,678,507
2021-12
What was the outcome of reaction 'Hepatitis E'?
Severe Hepatitis E virus infection in a patient with rheumatoid arthritis treated with baricitinib. A patient with rheumatoid arthritis (RA) was presented, who developed an infection with the hepatitis E virus (HEV) under treatment with the Janus kinase (JAK) 1 and 2 inhibitor baricitinib. In the 3‑month routine check-...
Recovered
ReactionOutcome
CC BY
34097102
20,631,649
2021-12
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Neuropathy peripheral'.
Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report. BACKGROUND Kaposi's sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Ma...
APIXABAN, BASILIXIMAB, EVEROLIMUS, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PACLITAXEL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34098936
19,552,202
2021-06-07
What was the dosage of drug 'BASILIXIMAB'?
Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report. BACKGROUND Kaposi's sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Ma...
INDUCTION THERAPY
DrugDosageText
CC BY
34098936
19,552,202
2021-06-07
What was the dosage of drug 'EVEROLIMUS'?
Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report. BACKGROUND Kaposi's sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Ma...
MAINTENANCE THERAPY
DrugDosageText
CC BY
34098936
19,552,202
2021-06-07
What was the dosage of drug 'METHYLPREDNISOLONE'?
Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report. BACKGROUND Kaposi's sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Ma...
INDUCTION THERAPY
DrugDosageText
CC BY
34098936
19,552,202
2021-06-07
What was the dosage of drug 'MYCOPHENOLATE MOFETIL'?
Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report. BACKGROUND Kaposi's sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Ma...
MAINTENANCE THERAPY
DrugDosageText
CC BY
34098936
19,552,202
2021-06-07
What was the dosage of drug 'PACLITAXEL'?
Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report. BACKGROUND Kaposi's sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Ma...
UNK, QW
DrugDosageText
CC BY
34098936
19,506,963
2021-06-07
What was the dosage of drug 'TACROLIMUS'?
Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report. BACKGROUND Kaposi's sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Ma...
MAINTENANCE THERAPY
DrugDosageText
CC BY
34098936
19,552,202
2021-06-07
What was the outcome of reaction 'Kaposi^s sarcoma'?
Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report. BACKGROUND Kaposi's sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Ma...
Recovered
ReactionOutcome
CC BY
34098936
19,464,738
2021-06-07
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hyponatraemia'.
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
BETAMETHASONE, CALCIUM, DEXTROSE, POTASSIUM, SODIUM CHLORIDE
DrugsGivenReaction
CC BY
34099019
19,499,359
2021-06-07
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hyponatraemic encephalopathy'.
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
BETAMETHASONE, CALCIUM, DEXTROSE, POTASSIUM, SODIUM CHLORIDE
DrugsGivenReaction
CC BY
34099019
19,499,359
2021-06-07
What is the weight of the patient?
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
2.8 kg.
Weight
CC BY
34099019
19,499,359
2021-06-07
What was the administration route of drug 'CALCIUM'?
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
34099019
19,499,359
2021-06-07
What was the administration route of drug 'DEXTROSE'?
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
34099019
19,499,359
2021-06-07
What was the administration route of drug 'POTASSIUM'?
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
34099019
19,499,359
2021-06-07
What was the administration route of drug 'SODIUM CHLORIDE'?
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
34099019
19,499,359
2021-06-07
What was the dosage of drug 'BETAMETHASONE'?
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
.375 mg (milligrams).
DrugDosage
CC BY
34099019
19,499,359
2021-06-07
What was the outcome of reaction 'Hyponatraemia'?
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
Recovered
ReactionOutcome
CC BY
34099019
19,499,359
2021-06-07
What was the outcome of reaction 'Hyponatraemic encephalopathy'?
From hypotonic maintenance fluid to severe hyponatremia: a case report. BACKGROUND The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increas...
Recovered
ReactionOutcome
CC BY
34099019
19,499,359
2021-06-07
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Off label use'.
Serious complications in COVID-19 ARDS cases: pneumothorax, pneumomediastinum, subcutaneous emphysema and haemothorax. The novel coronavirus identified as severe acute respiratory syndrome-coronavirus-2 causes acute respiratory distress syndrome (ARDS). Our aim in this study is to assess the incidence of life-threateni...
ASCORBIC ACID, AZITHROMYCIN ANHYDROUS, FAVIPIRAVIR, HYDROXYCHLOROQUINE
DrugsGivenReaction
CC BY
34099076
19,960,644
2021-06-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Deafness neurosensory'.
Liposomal amphotericin B-induced reversible ototoxicity in a patient with disseminated histoplasmosis. Amphotericin B (AmB) is a polyene antifungal agent used widely for systemic fungal infections. Infusion-related side effects, nephrotoxicity, and dyselectrolytemia are well-known adverse effects with the use of this d...
AMPHOTERICIN B
DrugsGivenReaction
CC BY-NC-SA
34100400
20,557,197
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Ototoxicity'.
Liposomal amphotericin B-induced reversible ototoxicity in a patient with disseminated histoplasmosis. Amphotericin B (AmB) is a polyene antifungal agent used widely for systemic fungal infections. Infusion-related side effects, nephrotoxicity, and dyselectrolytemia are well-known adverse effects with the use of this d...
AMPHOTERICIN B
DrugsGivenReaction
CC BY-NC-SA
34100400
20,557,197
2021
What was the administration route of drug 'AMPHOTERICIN B'?
Liposomal amphotericin B-induced reversible ototoxicity in a patient with disseminated histoplasmosis. Amphotericin B (AmB) is a polyene antifungal agent used widely for systemic fungal infections. Infusion-related side effects, nephrotoxicity, and dyselectrolytemia are well-known adverse effects with the use of this d...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY-NC-SA
34100400
20,557,197
2021
What was the outcome of reaction 'Deafness neurosensory'?
Liposomal amphotericin B-induced reversible ototoxicity in a patient with disseminated histoplasmosis. Amphotericin B (AmB) is a polyene antifungal agent used widely for systemic fungal infections. Infusion-related side effects, nephrotoxicity, and dyselectrolytemia are well-known adverse effects with the use of this d...
Recovered
ReactionOutcome
CC BY-NC-SA
34100400
20,557,197
2021
What was the outcome of reaction 'Ototoxicity'?
Liposomal amphotericin B-induced reversible ototoxicity in a patient with disseminated histoplasmosis. Amphotericin B (AmB) is a polyene antifungal agent used widely for systemic fungal infections. Infusion-related side effects, nephrotoxicity, and dyselectrolytemia are well-known adverse effects with the use of this d...
Recovered
ReactionOutcome
CC BY-NC-SA
34100400
20,557,197
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Off label use'.
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
ACETAMINOPHEN, CEFEPIME HYDROCHLORIDE, CYCLOBENZAPRINE, DAPTOMYCIN, ENOXAPARIN, METRONIDAZOLE, OXYCODONE, PREGABALIN, VANCOMYCIN
DrugsGivenReaction
CC BY-NC-ND
34101721
19,461,740
2021-06-08
What was the dosage of drug 'ACETAMINOPHEN'?
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
UNKNOWN
DrugDosageText
CC BY-NC-ND
34101721
19,471,520
2021-06-08
What was the dosage of drug 'CYCLOBENZAPRINE'?
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
UNKNOWN
DrugDosageText
CC BY-NC-ND
34101721
19,471,520
2021-06-08
What was the dosage of drug 'ENOXAPARIN'?
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
UNKNOWN
DrugDosageText
CC BY-NC-ND
34101721
19,471,520
2021-06-08
What was the dosage of drug 'OXYCODONE'?
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
UNKNOWN
DrugDosageText
CC BY-NC-ND
34101721
19,471,520
2021-06-08
What was the dosage of drug 'PREGABALIN'?
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
UNKNOWN
DrugDosageText
CC BY-NC-ND
34101721
19,471,520
2021-06-08
What was the outcome of reaction 'Leukopenia'?
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
Recovered
ReactionOutcome
CC BY-NC-ND
34101721
19,457,829
2021-06-08
What was the outcome of reaction 'Neutropenia'?
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
Recovered
ReactionOutcome
CC BY-NC-ND
34101721
19,454,214
2021-06-08
What was the outcome of reaction 'Thrombocytopenia'?
Neutropenia, Thrombocytopenia, and Eosinophilia: An Unusual Triad in a Patient on Long-Term Vancomycin Therapy. BACKGROUND Vancomycin is an antibiotic commonly used for management of severe gram-positive infections. It is infrequently associated with hematologic adverse effects, ranging from isolated thrombocytopenia o...
Recovered
ReactionOutcome
CC BY-NC-ND
34101721
19,454,214
2021-06-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Acute kidney injury'.
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
CARFILZOMIB
DrugsGivenReaction
CC BY
34101756
20,197,417
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Death'.
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
CARFILZOMIB
DrugsGivenReaction
CC BY
34101756
20,197,417
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Myeloma cast nephropathy'.
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
CARFILZOMIB
DrugsGivenReaction
CC BY
34101756
20,197,417
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Myositis'.
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
CARFILZOMIB
DrugsGivenReaction
CC BY
34101756
20,197,417
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Obstructive nephropathy'.
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
CARFILZOMIB
DrugsGivenReaction
CC BY
34101756
20,197,417
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Renal impairment'.
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
CARFILZOMIB
DrugsGivenReaction
CC BY
34101756
20,197,417
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Tubulointerstitial nephritis'.
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
CARFILZOMIB
DrugsGivenReaction
CC BY
34101756
20,197,417
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Urinary tract infection'.
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
CARFILZOMIB
DrugsGivenReaction
CC BY
34101756
20,197,417
2021
What was the outcome of reaction 'Acute kidney injury'?
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
Fatal
ReactionOutcome
CC BY
34101756
20,197,417
2021
What was the outcome of reaction 'Death'?
Immune checkpoint inhibitor-associated acute kidney injury and mortality: An observational study. Immune checkpoint inhibitors, approved for the treatment of various types of cancer, are known to cause a unique spectrum of side effects, including acute kidney injury (AKI). The aim of this study was to describe the inci...
Fatal
ReactionOutcome
CC BY
34101756
20,197,417
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Agranulocytosis'.
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
LACOSAMIDE, LEVETIRACETAM, PHENYTOIN SODIUM
DrugsGivenReaction
CC BY
34102997
19,549,181
2021-06-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Septic shock'.
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
LACOSAMIDE, LEVETIRACETAM, PHENYTOIN SODIUM
DrugsGivenReaction
CC BY
34102997
19,549,181
2021-06-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Sinus bradycardia'.
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
LACOSAMIDE, LEVETIRACETAM, PHENYTOIN SODIUM
DrugsGivenReaction
CC BY
34102997
19,549,181
2021-06-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Sinus node dysfunction'.
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
LACOSAMIDE, LEVETIRACETAM, PHENYTOIN SODIUM
DrugsGivenReaction
CC BY
34102997
19,549,181
2021-06-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Somnolence'.
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
LACOSAMIDE, LEVETIRACETAM, PHENYTOIN SODIUM
DrugsGivenReaction
CC BY
34102997
19,549,181
2021-06-08
What is the weight of the patient?
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
42 kg.
Weight
CC BY
34102997
19,549,181
2021-06-08
What was the administration route of drug 'LACOSAMIDE'?
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
Oral
DrugAdministrationRoute
CC BY
34102997
19,549,181
2021-06-08
What was the outcome of reaction 'Agranulocytosis'?
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
Recovering
ReactionOutcome
CC BY
34102997
19,549,181
2021-06-08
What was the outcome of reaction 'Septic shock'?
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
Fatal
ReactionOutcome
CC BY
34102997
19,549,181
2021-06-08
What was the outcome of reaction 'Sinus bradycardia'?
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
Recovering
ReactionOutcome
CC BY
34102997
19,549,181
2021-06-08
What was the outcome of reaction 'Sinus node dysfunction'?
Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis. BACKGROUND Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunc...
Recovering
ReactionOutcome
CC BY
34102997
19,549,181
2021-06-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Off label use'.
Anti-PD-1 elicits regression of undifferentiated pleomorphic sarcomas with UV-mutation signatures. Undifferentiated pleomorphic sarcoma (UPS), an aggressive soft-tissue sarcoma of adults, has been characterized by low tumor mutational burden (TMB) and high copy number alterations. Clinical trials of programmed death-1 ...
DOCETAXEL, GEMCITABINE\GEMCITABINE HYDROCHLORIDE
DrugsGivenReaction
CC BY-NC
34103354
19,850,231
2021-06
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Off label use'.
Near Complete Pathologic Response to PD-1 Inhibitor and Radiotherapy in a Patient with Locally Advanced Pancreatic Ductal Adenocarcinoma. Pancreatic ductal adenocarcinoma (PDAC) remains deadly despite advances in systemic therapies and surgical techniques. While there is increasing utilization of immune therapies acros...
PEMBROLIZUMAB
DrugsGivenReaction
CC BY-NC
34103944
19,498,758
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Disease progression'.
Dramatic response of refractory metastatic squamous cell carcinoma of the skin with cetuximab/pembrolizumab. Cutaneous squamous cell carcinoma (cSCC) accounts for 20% of skin cancers. At an advanced stage the prognosis is poor, making cSCC the second leading cause of death from skin cancer. In cases of metastatic or un...
CARBOPLATIN, CETUXIMAB
DrugsGivenReaction
CC BY-NC
34104225
20,599,713
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Treatment failure'.
Dramatic response of refractory metastatic squamous cell carcinoma of the skin with cetuximab/pembrolizumab. Cutaneous squamous cell carcinoma (cSCC) accounts for 20% of skin cancers. At an advanced stage the prognosis is poor, making cSCC the second leading cause of death from skin cancer. In cases of metastatic or un...
CARBOPLATIN, CETUXIMAB, PEMBROLIZUMAB
DrugsGivenReaction
CC BY-NC
34104225
20,568,250
2021
What was the dosage of drug 'CARBOPLATIN'?
Dramatic response of refractory metastatic squamous cell carcinoma of the skin with cetuximab/pembrolizumab. Cutaneous squamous cell carcinoma (cSCC) accounts for 20% of skin cancers. At an advanced stage the prognosis is poor, making cSCC the second leading cause of death from skin cancer. In cases of metastatic or un...
UNK, CYCLE (RECEIVED AS FIRST-LINE SYSTEMIC THERAPY)
DrugDosageText
CC BY-NC
34104225
20,568,250
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Ischaemic stroke'.
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
ACETAMINOPHEN, ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, ENOXAPARIN SODIUM, HYDROXYCHLOROQUINE, LOPINAVIR\RITONAVIR
DrugsGivenReaction
CC BY
34104245
19,654,452
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Off label use'.
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
ACETAMINOPHEN, ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, ENOXAPARIN SODIUM, HYDROXYCHLOROQUINE, LOPINAVIR\RITONAVIR
DrugsGivenReaction
CC BY
34104245
19,654,452
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Subarachnoid haemorrhage'.
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
ACETAMINOPHEN, ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, ENOXAPARIN SODIUM, HYDROXYCHLOROQUINE, LOPINAVIR\RITONAVIR
DrugsGivenReaction
CC BY
34104245
19,654,452
2021
What was the dosage of drug 'ACETAMINOPHEN'?
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
2 GRAM
DrugDosageText
CC BY
34104245
19,654,452
2021
What was the dosage of drug 'ASPIRIN'?
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
75 MILLIGRAM, DAILY
DrugDosageText
CC BY
34104245
19,654,452
2021
What was the dosage of drug 'ATORVASTATIN'?
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
40 MILLIGRAM, DAILY
DrugDosageText
CC BY
34104245
19,654,452
2021
What was the dosage of drug 'CLOPIDOGREL BISULFATE'?
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
75 MILLIGRAM, DAILY
DrugDosageText
CC BY
34104245
19,654,452
2021
What was the dosage of drug 'ENOXAPARIN SODIUM'?
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
6000 INTERNATIONAL UNIT, DAILY
DrugDosageText
CC BY
34104245
19,654,452
2021
What was the dosage of drug 'HYDROXYCHLOROQUINE'?
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
800 UNK, DAILY
DrugDosageText
CC BY
34104245
19,654,452
2021
What was the outcome of reaction 'Ischaemic stroke'?
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
Recovering
ReactionOutcome
CC BY
34104245
19,654,452
2021
What was the outcome of reaction 'Subarachnoid haemorrhage'?
Neurological complications in COVID-19 - a diagnostic challenge. With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. R...
Recovering
ReactionOutcome
CC BY
34104245
19,654,452
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Abdominal pain upper'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Abdominal pain'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Chest pain'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Dyspepsia'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Dysphagia'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Eructation'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hiccups'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Immunosuppressant drug level increased'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,419,061
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Nausea'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Odynophagia'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Product use in unapproved indication'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,434,419
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Regurgitation'.
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
ALEMTUZUMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS
DrugsGivenReaction
CC BY
34104254
19,523,148
2021
What was the administration route of drug 'METHYLPREDNISOLONE'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
34104254
19,595,104
2021
What was the administration route of drug 'PREDNISONE'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Oral
DrugAdministrationRoute
CC BY
34104254
19,595,104
2021
What was the outcome of reaction 'Abdominal pain upper'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Recovered
ReactionOutcome
CC BY
34104254
19,523,148
2021
What was the outcome of reaction 'Abdominal pain'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Recovered
ReactionOutcome
CC BY
34104254
19,523,148
2021
What was the outcome of reaction 'Chest pain'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Recovered
ReactionOutcome
CC BY
34104254
19,523,148
2021
What was the outcome of reaction 'Dyspepsia'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Recovered
ReactionOutcome
CC BY
34104254
19,523,148
2021
What was the outcome of reaction 'Dysphagia'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Recovered
ReactionOutcome
CC BY
34104254
19,523,148
2021
What was the outcome of reaction 'Eructation'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Recovered
ReactionOutcome
CC BY
34104254
19,523,148
2021
What was the outcome of reaction 'Hiccups'?
Acute esophageal necrosis following kidney transplantation. We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical pro...
Recovered
ReactionOutcome
CC BY
34104254
19,523,148
2021