task
stringclasses
5 values
input
stringlengths
89
339
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC[C@H](C)[C@@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(N)=O ### Response: 5
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CNC(=O)[C@@H]1CCCN(S(=O)(=O)c2ccc(OC(C)C)cc2)C1 ### Response: 0
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [10*]N1CCC(=O)N2CCCC[C@H]2C1=O Fragment 2: [8*][C@H](CCC)COC ### Response: CCC[C@H](COC)N1CCC(=O)N2CCCC[C@H]2C1=O
ring_counting
### Instruction: Count the six-membered rings in the following molecule. O=C(NCCc1ccccc1)C1CCN(C(=O)c2cc3oc(-c4ccccc4)cc3[nH]2)CC1 ### Response: 3
functional_group
### Instruction: Does the molecule contain a amide group? C[C@@H](CCc1ccccc1)NC(=O)c1nc2ccccc2c(=O)[nH]1 ### Response: Yes
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC1=NN(c2ccc(Cl)c(C(=O)[O-])c2)C(=O)/C1=C\c1ccccc1Cl ### Response: 1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC1(C)[C@@H]2CC[C@@]1(C(=O)Oc1ccc(Cl)cc1Cl)C(=O)C2 ### Response: 2
functional_group
### Instruction: Does the molecule contain a hydroxyl group? CC(C)([NH2+]CCCn1cncn1)c1ccc(Cl)cc1 ### Response: No
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? O=C(NC1CC[NH+](Cc2ccccc2)CC1)c1ccc(CN2C(=O)CCn3nccc32)cc1 ### Response: 1
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? O=[N+]([O-])c1ccc(Cl)cc1[N-]S(=O)(=O)c1ccccc1F ### Response: Yes
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1ccccc1F Fragment 2: [5*]NCCC(=O)OC ### Response: COC(=O)CCNC(=O)c1ccc(NC(=O)c2ccccc2F)cc1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. COc1cc(C)c(C[NH+]2CCC(N3CCCC3=O)CC2)cc1OC ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [4*]C(C)(C)C[NH3+] Fragment 2: [14*]c1ncc(Br)cc1C ### Response: Cc1cc(Br)cnc1N1CCN(C(C)(C)C[NH3+])CC1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*][NH+](C)C1CCCC1 Fragment 2: [15*][C@@H]1CCC(C)(C)[C@H]1O ### Response: C[NH+](C1CCCC1)[C@@H]1CCC(C)(C)[C@H]1O
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(C(=O)O[C@@H](C)c2nc3ccccc3n2C)ccoc1 ### Response: C[C@H](OC(=O)c1ccoc1)c1nc2ccccc2n1C
canonicalization
### Instruction: Canonicalize the following SMILES string. C(c1c(C[NH2+]Cc2cocc2)ccc(c1)F)SC ### Response: CSCc1cc(F)ccc1C[NH2+]Cc1ccoc1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]NCc1ccc([14*])[nH+]c1 Fragment 2: [5*]NCC[8*] ### Response: CC1CCN(c2ccc(CNC(=O)NCCn3cccc3)c[nH+]2)CC1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [16*]c1ccccc1 Fragment 2: [4*]Cc1cnc(C)n1[9*] ### Response: CCN(CCC(F)(F)F)Cc1cnc(C)n1-c1ccccc1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC[C@H](Oc1ccc(F)cc1)C(=O)Nc1nc2c(s1)CCCC2 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [16*]c1ccccc1 Fragment 2: [4*]C[C@@H]([4*])C ### Response: Cc1ccc(S(=O)(=O)NC[C@H](C)Oc2ccccc2)c(F)c1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. Cc1ccc(NC(=O)C[S@@](=O)CC(=O)Nc2ccc3c(c2)CCC3)cc1Cl ### Response: 2
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1cn([9*])nn1 Fragment 2: [1*]C(=O)c1ccc(C)c(C)c1 ### Response: Cc1ccc(C(=O)NC2CCN(C(=O)c3cn(-c4ccc(F)c(C)c4)nn3)CC2)cc1C
canonicalization
### Instruction: Canonicalize the following SMILES string. C[C@@H](C[C@H](c1cc(C2CC2)ccc1)O)C(=O)OC ### Response: COC(=O)[C@@H](C)C[C@@H](O)c1cccc(C2CC2)c1
canonicalization
### Instruction: Canonicalize the following SMILES string. c12cc(-c3nnc(n3CC=C)SCC(=O)Nc3cccc(c3)C)oc1cccc2 ### Response: C=CCn1c(SCC(=O)Nc2cccc(C)c2)nnc1-c1cc2ccccc2o1
functional_group
### Instruction: Does the molecule contain a carboxyl group? COc1cccc(/C=N/c2ccc(S(=O)(=O)[N-]c3nccs3)cc2)c1OC ### Response: No
canonicalization
### Instruction: Canonicalize the following SMILES string. C1Cc2c(CC1)sc1c2c(=O)[nH]c(CSc2nnnn2C2CCCC2)n1 ### Response: O=c1[nH]c(CSc2nnnn2C2CCCC2)nc2sc3c(c12)CCCC3
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1cnn(C[8*])c1 Fragment 2: [15*][C@H]1CCOC1 ### Response: C[C@H](OC(=O)c1cnn(Cc2ccccc2)c1)[C@H]1CCOC1
functional_group
### Instruction: Does the molecule contain a thiol group? COc1ccc(S(=O)(=O)N(Cc2ccccc2)c2ccccc2C(=O)[O-])cc1 ### Response: No
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? Clc1cccc(C2(NCc3nc4c(s3)CCC4)CC2)c1 ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. C[C@@H](c1cnc(nc1C)C)N[C@@H]1CN(C(OC(C)(C)C)=O)C[C@@H]1OC ### Response: CO[C@H]1CN(C(=O)OC(C)(C)C)C[C@H]1N[C@@H](C)c1cnc(C)nc1C
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CCCCC1CCC(NC(=O)c2cnn(-c3ccc([O-])nn3)c2C)CC1 ### Response: 2
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? COc1ccc(NC(=O)[C@H](C)SC2=C(C#N)C(C)(C)[C@@H](C#N)C(=O)N2)cc1 ### Response: 3
canonicalization
### Instruction: Canonicalize the following SMILES string. n1(-c2nnc(cc2)N2CCOCC2)c2c(c(C)n1)[C@H](c1ccc(cc1)OCCC)CC(N2)=O ### Response: CCCOc1ccc([C@@H]2CC(=O)Nc3c2c(C)nn3-c2ccc(N3CCOCC3)nn2)cc1
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? C/C(Cc1ccccc1)=N\NC(=O)c1c[nH]c(=O)[nH]c1=O ### Response: Yes
ring_counting
### Instruction: Count the six-membered rings in the following molecule. O=C1CC[C@H](C(=O)N2CCC[C@H]2c2ccc(F)cc2)N1 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*][NH2+]CC[7*] Fragment 2: [4*]C/C=C/c1ccccc1 ### Response: CCc1nn(C)cc1C[NH2+]C/C=C/c1ccccc1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(C)CCC(=O)[C@H](C#N)c1ncc(C(F)(F)F)cc1Cl ### Response: 7
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CC[C@@](C)(NC(=O)NC(C)(C)C)c1ccccc1 ### Response: 1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? N#Cc1ccc(OCc2nc3ccccc3c(=O)[nH]2)cc1F ### Response: 1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. COCCCNC(=O)Cn1cccc1[C@@H](C)O ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. N[C@H](c1[nH]cc(C(=O)[O-])n1)c1ccccc1OC ### Response: COc1ccccc1[C@H](N)c1nc(C(=O)[O-])c[nH]1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CN(CC(=O)N1CCNC1=O)Cc1ccccc1C(F)(F)F ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1ccccc1Cn1c(N)c(c(CCC)n1)CCC ### Response: CCCc1nn(Cc2ccccc2)c(N)c1CCC
canonicalization
### Instruction: Canonicalize the following SMILES string. C1CN(S(=O)(C[C@@H](C)CCl)=O)C[C@@H]1C ### Response: C[C@@H]1CCN(S(=O)(=O)C[C@@H](C)CCl)C1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? C[NH+](Cc1ccc([S@](C)=O)cc1)C1CCC(C)(C)CC1 ### Response: 1
functional_group
### Instruction: Does the molecule contain a amide group? C[C@H](C(=O)[O-])N1C(=O)/C(=C/c2ccccc2F)SC1=S ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? O=C1CC2(CCCCC2)C(=O)N1CC(=O)N(Cc1ccccc1)C1CC1 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. O=C(OCC)N1CCN(Cc2n(c3c(n2)n(c(=O)n(c3=O)C)C)Cc2c(cccc2)Cl)CC1 ### Response: CCOC(=O)N1CCN(Cc2nc3c(c(=O)n(C)c(=O)n3C)n2Cc2ccccc2Cl)CC1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. Cc1ccc(C(=O)[C@H](C)Sc2nnc(-c3ccc4c(c3)OCO4)o2)cc1 ### Response: 2
functional_group
### Instruction: Does the molecule contain a phenol group? C[NH+]1CCN(C(=O)c2ccccc2NC(=S)NC(=O)c2ccco2)CC1 ### Response: No
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [4*][C@H](C)CS(=O)(=O)CC Fragment 2: [5*][NH2+][C@@H]1C[C@H](C)CC[C@@H]1[15*] ### Response: CCS(=O)(=O)C[C@@H](C)[NH2+][C@@H]1C[C@H](C)CC[C@@H]1C(C)C
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [8*]CCc1ccccn1 Fragment 2: [14*]c1ccccn1 ### Response: Cc1cc(N2C[C@H]3OC(=O)N(CCc4ccccn4)[C@H]3C2)c2ccccc2[nH+]1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? COc1ccc(C[C@H](C)[NH2+][C@H]2CCCC[C@@H]2C)cc1OC ### Response: 3
canonicalization
### Instruction: Canonicalize the following SMILES string. c1ccccc1[C@@H]1C[C@@H]1n1c(=S)[nH]c2c1ncc(Br)c2 ### Response: S=c1[nH]c2cc(Br)cnc2n1[C@H]1C[C@H]1c1ccccc1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [13*][C@H]1C=C(c2cccc([16*])c2)N=N1 Fragment 2: [3*]OCC ### Response: CCOc1cccc(C2=C[C@H](C(=O)N/N=C/c3ccc(OC)cc3)N=N2)c1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [8*]C(C)(C)C Fragment 2: [5*][NH2+]Cc1ncn(C)n1 ### Response: Cn1cnc(C[NH2+]Cc2ccc(C(C)(C)C)cc2)n1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(-c2ccc(cc2)OC)oc(nn1)SCC(N[C@H](C)c1cc(Cl)c(cc1)Cl)=O ### Response: COc1ccc(-c2nnc(SCC(=O)N[C@H](C)c3ccc(Cl)c(Cl)c3)o2)cc1
functional_group
### Instruction: Does the molecule contain a amide group? CCCN1CCN(C(=O)CCn2c(=O)c3cccn3c3cccnc32)CC1 ### Response: Yes
canonicalization
### Instruction: Canonicalize the following SMILES string. c12C(=O)CCCc2ccc(NC(=O)N[C@H](CCOC)C)c1 ### Response: COCC[C@H](C)NC(=O)Nc1ccc2c(c1)C(=O)CCC2
functional_group
### Instruction: Does the molecule contain a carboxyl group? C[C@@H]1CCCC[NH+]1C[C@@H]1CCCN(CC(=O)N2CCc3ccccc3C2)C1 ### Response: No
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CCn1c(SCC(=O)c2ccc(OC)cc2)nc2ccccc21 ### Response: 2
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [14*]c1cc(C)nc([14*])n1 Fragment 2: [15*]C1CC[NH2+]CC1 ### Response: Cc1cc(-c2ccc(S(C)(=O)=O)cc2)nc(C2CC[NH2+]CC2)n1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1cc(C)cc(c1Cl)O[C@@H](C)C(=O)N[C@H]1[C@H](Cc2c1cccc2)O ### Response: Cc1ccc(Cl)c(O[C@@H](C)C(=O)N[C@@H]2c3ccccc3C[C@@H]2O)c1
canonicalization
### Instruction: Canonicalize the following SMILES string. n1n(-c2ccc(cc2)C)cc(c1-c1ccccc1)C(=O)N1CCN(C([C@@H]2OCCC2)=O)CC1 ### Response: Cc1ccc(-n2cc(C(=O)N3CCN(C(=O)[C@H]4CCCO4)CC3)c(-c3ccccc3)n2)cc1
canonicalization
### Instruction: Canonicalize the following SMILES string. O=C(NC)c1ccc(o1)C[NH+]1CCC(=CC1)[C@@H](C)N(C)C(C)=O ### Response: CNC(=O)c1ccc(C[NH+]2CC=C([C@@H](C)N(C)C(C)=O)CC2)o1
functional_group
### Instruction: Does the molecule contain a thiol group? C[C@H](NC(=O)C[C@H]1CCS(=O)(=O)C1)c1ccc(-n2cccn2)cc1 ### Response: No
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(C)c1ccc2c(c1)[C@]1(CC(O)=Nc3c1cnn3Cc1ccccc1Cl)C(=O)N2C ### Response: 3
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N([5*])CC Fragment 2: [4*]C[C@@H](C)CC ### Response: CC[C@H](C)CN(CC)S(=O)(=O)c1cc(F)ccc1N
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [11*]Sc1nnc2c(n1)O[C@@H](CC)Nc1ccccc1-2 Fragment 2: [4*]CCCC ### Response: CCCCSc1nnc2c(n1)O[C@@H](CC)Nc1ccccc1-2
functional_group
### Instruction: Does the molecule contain a thiol group? CO/N=C/c1ccc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cc1 ### Response: No
ring_counting
### Instruction: Count the five-membered rings in the following molecule. O=C(CSc1ccnc(C(=O)[O-])c1)NNc1ccccn1 ### Response: 0
ring_counting
### Instruction: Count the five-membered rings in the following molecule. Cc1cccc(Nc2ccccc2C(=O)NNC(=O)C(=O)NC(C)C)c1C ### Response: 0
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [16*]c1cc(Cl)c([16*])c(OC)c1 Fragment 2: [8*]C[NH2+]C ### Response: C[NH2+]Cc1cc(Cl)c(OCCC(C)C)c(OC)c1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. Cc1cccc(CC(=O)NC[C@H](c2ccccc2)[NH+](C)C)c1 ### Response: 0
canonicalization
### Instruction: Canonicalize the following SMILES string. n1c(N(C)C)ncc(-c2cccc(c2)Cl)c1C1CCN(CC1)C(=O)C[C@@H]1CCCCO1 ### Response: CN(C)c1ncc(-c2cccc(Cl)c2)c(C2CCN(C(=O)C[C@@H]3CCCCO3)CC2)n1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(C)([C@@H](N)[C@H]1CCc2cccnc21)[NH+]1CCCCCC1 ### Response: 3
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [15*]C1C(C)(C)C1(C)C Fragment 2: [16*]c1cccc(C(N)=S)c1 ### Response: CC1(C)C(NS(=O)(=O)Cc2cccc(C(N)=S)c2)C1(C)C
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1cc(OC)ccc1Br Fragment 2: [5*]N[C@@H](CCC)C(=O)OC ### Response: CCC[C@H](NC(=O)c1cc(OC)ccc1Br)C(=O)OC
canonicalization
### Instruction: Canonicalize the following SMILES string. C1C[C@@H](OC1)C(Nc1ccc(cc1)NCc1ccc(cc1)F)=O ### Response: O=C(Nc1ccc(NCc2ccc(F)cc2)cc1)[C@H]1CCCO1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(C(NC[C@H]2CCC[C@@H](O)C2)=O)c(O)ccc(C)c1 ### Response: Cc1ccc(O)c(C(=O)NC[C@H]2CCC[C@@H](O)C2)c1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(C)=O Fragment 2: [5*]N1CCc2ccccc21 ### Response: CC(=O)N[C@@H](CC(=O)OCC(=O)N1CCc2ccccc21)c1ccc(Cl)cc1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N1CCC[C@]([15*])(CO)C1 Fragment 2: [4*]Cc1[nH]cc(C)c(=O)c1C ### Response: COCC[C@]1(CO)CCCN(Cc2[nH]cc(C)c(=O)c2C)C1
canonicalization
### Instruction: Canonicalize the following SMILES string. c12n(c(c(c(n2)N2CCCC2)/C=N/NC(c2ccncc2)=O)=O)cccc1C ### Response: Cc1cccn2c(=O)c(/C=N/NC(=O)c3ccncc3)c(N3CCCC3)nc12
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? Cc1ccc([C@@H](Cl)[C@H]2CCO[C@@H]2C)c2ccccc12 ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? C[C@@H](Nc1ccc(Oc2ccc(C#N)cc2)cc1)c1nc(C2CC2)no1 ### Response: 2
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [14*]c1cccs1 Fragment 2: [5*]N1CCOCC1 ### Response: C[NH2+][C@H](c1cccs1)C(C)(C)N1CCOCC1
canonicalization
### Instruction: Canonicalize the following SMILES string. C(Cn1nccc1)CCCN1CCn2c([C@@H]1c1ccccc1)ccc2 ### Response: c1ccc([C@H]2c3cccn3CCN2CCCCCn2cccn2)cc1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CC[C@@](C)([NH3+])c1nc(-c2ccc(C)c(F)c2)no1 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]NCCC Fragment 2: [14*]c1nc2ccccc2s1 ### Response: CCCNC(=O)C[S@@](=O)Cc1nc2ccccc2s1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CCCCn1nc(C)c(C(=O)N[C@H](C)Cc2ccco2)c1Cl ### Response: 2
functional_group
### Instruction: Does the molecule contain a amide group? O=C(C[NH+](Cc1ccncc1)C1CC1)NCc1cc(F)cc(F)c1 ### Response: Yes
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CCO[C@H](C)C(=O)OCC(=O)NC(C)C ### Response: 0
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(=O)NCC(=O)N[C@@H](C(=O)Nc1ccc2c(c1)OCO2)c1ccccc1 ### Response: 2
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)C1=Cc2ccccc2OC1 Fragment 2: [4*][C@@H](CCN[5*])C(C)C ### Response: CCO[C@@H](CCNC(=O)C1=Cc2ccccc2OC1)C(C)C
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? COc1ccc(OC)c(N/C([S-])=[NH+]\N2CCOCC2)c1 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]NCCC[8*] Fragment 2: [1*]C(=O)CC[8*] ### Response: O=C(CCc1ccccc1O)NCCCn1cccn1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(C)(C)Oc1ccc(C(=O)Nc2ccc(NC(=O)NC3CC3)cc2)cc1 ### Response: 3
canonicalization
### Instruction: Canonicalize the following SMILES string. C1C[NH+](CCNC(NCC(C)(C)c2ccncc2)=O)CCC1OC ### Response: COC1CC[NH+](CCNC(=O)NCC(C)(C)c2ccncc2)CC1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N(C)C[8*] Fragment 2: [4*]Cc1ccc(C)s1 ### Response: Cc1ccc(CN(C)C(=O)NCC(=O)Nc2ccc(Cl)cc2)s1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. O=S(=O)(NCc1ccc2c(c1)OCCO2)C1CCOCC1 ### Response: 3