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Augmentation rhinoplasty among Asian patients is often performed to improve the height of the nasal dorsum. As the use of autogenous tissues poses certain limitations, alloplastic materials are a viable alternative with a long history of use in Asia. The superiority of one implant prosthesis over another for augmentati... |
BACKGROUND |
Latent autoimmune diabetes in adults (LADA) is a slowly developing type 1 diabetes. |
OBJECTIVES |
To compare interventions used for LADA. |
SEARCH STRATEGY |
Studies were obtained from searches of electronic databases, supplemented by handsearches, conference proceedings and consultation with experts. Date of last search was December 2010. |
SELECTION CRITERIA |
Randomised controlled trials (RCT) and controlled clinical trials (CCT) evaluating interventions for LADA or type 2 diabetes with antibodies were included. |
DATA COLLECTION AND ANALYSIS |
Two authors independently extracted data and assessed risk of bias. Studies were summarised using meta-analysis or descriptive methods. |
MAIN RESULTS |
Searches identified 13,306 citations. Fifteen publications (ten studies) were included, involving 1019 participants who were followed between three months to 10 years (1060 randomised). All studies had a high risk of bias. Sulphonylurea (SU) with insulin did not improve metabolic control significantly more than insulin... |
AUTHORS' CONCLUSIONS |
Two studies show SU leading to earlier insulin dependence and a meta-analysis of four studies with considerable heterogeneity showed poorer metabolic control if SU is prescribed for patients with LADA compared to insulin. One study showed that vitamin D with insulin may protect pancreatic beta cells in LADA. Novel trea... |
ABSTRACT The Pseudomonas putida KT2440 TOL upper pathway is repressed under nonlimiting conditions in cells growing in chemostat with succinate as a carbon source. We show that the ptsN gene product IIANtr participates in this repression. Crc, involved in yeast extract-dependent repression in batch cultures, did not in... |
The organizational innovation is the main force for the enterprise to precede daily operation work. And the destination and direction of the organization innovation is the most important element for the organization innovation. So how to locate and choose the optimal path of the organization innovation is the emergency... |
Optical interconnects offer significant advantages for future high performance computers and large scale data centers. The development of low-voltage and high-speed modulators would be a challenge for further increase of the link capacity with low power consumption. we present the modeling and the experiment toward ult... |
Abstract Hedged mutual funds flourished following the 2007–2009 financial crisis. They became particularly popular with financial advisors because of their alleged downside protection. Did these funds deliver what they promised? We examine the performance of these funds with a focus on the post-2009 period. While they ... |
Patients admitted to hospitals in tropical Africa are at increased risk for nosocomial infection. However accurate description of this risk is difficult due to a lack of published data in the literature. The main promoting factors are poor health care facilities, high microbial levels in the hospital and community envi... |
Language-based security relies on the assumption that all potential attacks follow the rules of the language in question. When programs are compiled into a different language, this is true only if the translation process preserves observational equivalence. To prove that a translation preserves equivalence, one must sh... |
Transthyretin (TTR), synthesized by the choroid plexus (CP) and secreted into cerebrospinal fluid (CSF), is involved in thyroxine (T4) transport and chelation of beta-amyloid peptide, attenuating neurotoxicity. To characterize age-related changes in TTR synthesis, CSF and CPs were collected from young adult (1-2 years)... |
Background: Infertility is a worldwide problem affecting about 10-15% of married couples and has social, economic and psychological implications1. A significant number of couples will require assisted reproduction following failure of common treatment options. Undergraduates form a rich source of potential gamete donor... |
Objectives: This study aimed to assess the knowledge and attitude of participants about assisted reproduction and to further evaluate their willingness to donate gametes for assisted conception or act as surrogates. |
Methodology: This was a cross-sectional descriptive study of 1150 participants consisting of 511 male students and 639 female students of the University of Ibadan. Participants were selected by simple random sampling technique. A semistructured, self-administered questionnaire was used to obtain information on sociodem... |
Results: Eight seven percent of the respondents had good knowledge of Assisted Reproductive Techniques (ART) and the most common source of awareness was the media (63.3%). More respondents were aware of sperm donation (75.5%)compared to egg donation (61.9%). Ninety percent of the participants were correctly able to ide... |
The article challenges educators to rethink reading instruction practices for students who are deaf or hard of hearing. The authors begin with a discussion of the role of phonology in reading, then summarize the evidence of phonological coding among skilled deaf readers and investigate alternative routes for acquiring ... |
In this study, the effects of nitrogen codoping on the microstructure and mechanical properties of Cr-doped diamond-like carbon (DLC) nanocomposite coatings were investigated in detail. Compared with undoped DLC coatings, the Cr-DLC and N/Cr-DLC coatings showed higher root-mean-square (RMS) roughness values. However, f... |
Recent developments allow to make antennas from flexible materials and use their flexibility to make some shapes on movable bases, including clothes, shoes, human body and other curved surfaces. Influence of inset fed rectangular microstrip antenna cylindrical deformation on its frequency properties and directivity is ... |
Improving the photoluminescence (PL) efficiency of organic luminescent molecules is still a great challenge. Herein, a novel zero-dimensional Sn(IV)-based halide (C9H8N)2SnCl6 is prepared by assembling inactive quinoline cations and stable [SnCl6]2- polyhedra. Experimental characterizations and theoretical calculations... |
Seventy‐six children aged 5 months to 15 years who exhibited a net weal of 3.0 mm or greater to a puncture skin test with one or more of fourteen foods were subjected to double‐blind food challenge. Confirmed reactions to double‐blind food challenge were found to occur only with peanut, milk, egg and soybean. Puncture ... |
In this study the model system between strawberry anthocyanins and chlorogenic acid was investigated. Pigment:copigment system was observed at different concentration of copigment and in different temperatures. The absorption was determined at heating system from 20 to 50 °C and following cooling the same system from 5... |
A critical analysis and interpretation of the data published for complexation (conditional stability constants and complexation capacities) of trace metals (copper, Cu(II); zinc, Zn(II); lead, Pb(II); and cadmium, Cd(II)) in whole seawater and freshwater samples over the past 34 yr is presented. We propose that it is n... |
Maternal plasma and serum are being used to detect fetal DNA by PCR in order to determine certain conditions such as fetal gender and RhD without invasive procedures. Because of the presence of maternal DNA in plasma, these approaches are limited to paternally inherited disorders or those de novo present in the fetus. ... |
We propose a continuous-time heterogeneous agent model consisting of fundamental, momentum, and contrarian traders to explain the significant time series momentum. We show that the market under-reacts in short-run and overreacts in long-run when momentum traders dominate the market, which provides profit opportunity fo... |
A 26-year-old healthy male patient's fundus revealed findings consistent with torpedo maculopathy. Swept-source optical coherence tomography (OCT) showed a dome-shaped elevation of the retina at the level of ellipsoid zone. On OCT angiography segmented at the level of the choriocapillaris, a cluster of convoluted fine ... |
Specimens of the paneuarthropod Campanamuta mantonae gen. et sp. nov. are described from the lower Cambrian Sirius Passet Fauna of North Greenland. It is one of the most common taxa in the present collections from the Sirius Passet Fauna, being represented by some 1700 specimens (19%) of an estimated total of perhaps 8... |
Plasmalemmal Cl−–HCO3− exchangers regulate intracellular pH and [Cl−] and cell volume. In polarized epithelial cells, they contribute also to transepithelial secretion and reabsorption of acid–base equivalents and of Cl−. Members of both the SLC4 and SLC26 mammalian gene families encode Na+‐independent Cl−–HCO3− exchan... |
The sonic hedgehog (SHH) signaling pathway exhibits aberrant activation in triple-negative breast cancer (TNBC), wherein it regulates several malignant phenotypes related to tumor metastasis. GANT61, an inhibitor of the SHH signaling pathway, may offer promise when administered in combination with conventional chemothe... |
A power and area efficient hardware encoding system tailored for wireless implantable applications is presented. Constant medical monitoring allowed by implantable devices is the most relevant alternative to current bulky monitoring systems, which, in case of severe mental diseases, require heavy surgery and long term ... |
We present a high dynamic range (HDR) imaging algorithm that utilizes a modern rank minimization framework. Linear dependency exists among low dynamic range (LDR) images. However, global or local misalignment by camera motion and moving objects breaks down the low-rank structure of LDR images. The proposed algorithm si... |
ABSTRACT Focusing on a process where a designer embeds herself in craftspeople’s workshops with the intention of ‘learning from inside’ and ‘making together’; this paper proposes pathways for considering collaboration between designers and craftspeople via digital fabrication and weaving. The tension of forces that mak... |
We analysed 112 idiopathic inflammatory myopathy (IIM) sera for the presence of anti‐Ro, anti‐La and anti‐histidyl‐tRNA synthetase (Jo‐1) autoantibodies, and subsequently mapped B cell epitopes on the Ro52 protein recognized by anti‐Ro52+ IIM sera. Sera were characterized by immunoblotting, ELISA and RNA precipitation.... |
Translation of mRNA into protein requires the processive decoding of mRNA triplets into amino acids with concurrent formation of peptide bonds. These interdependent events are mediated by the ribosome in association with other cellular components. The complexity of the translation process makes it a likely candidate fo... |
Background Localised CAG repeat expansion is a characteristic of both human HD and mouse model brains and could potentially contribute to the development of cellular dysfunction through the expression of progressively longer poly Q containing protein. A derivative of the R6/1 mouse expressing 89Q (Vatsavayai et al (200... |
Nowadays time series are generated relatively more easily and in larger quantity than ever, by the advances of IoT and sensor applications. Training a prediction model effectively using such big data streams poses certain challenges in machine learning. Data sampling has been an important technique in handling over-siz... |
offer visual support for analyzing complex domains such as business processes and information systems. In both cases, models are developed using graphical modelling languages. In our study we focus on usability evaluation of modelling languages for the model interpretation scenario. The study is based on a causal model... |
K-dominant skyline query technology reduces the result sets for a dataset with high dimensional spaces, which is more convenient for user to make decision. But all the existent algorithms are for static k, not suitable for dynamic k. To solve this problem, this paper proposed a new idea, updating the k-dominant skyline... |
ABSTRACT Glucocorticoid production in the adrenal cortex is activated in response to an increase in cyclic AMP (cAMP) signaling. The nuclear protein p54nrb/NONO belongs to the Drosophila behavior/human splicing (DBHS) family and has been implicated in several nuclear processes, including transcription, splicing, and RN... |
The self-excited oscillation pulsed jet (SOPJ) is widely used owing to its simple structure and good separation of pressure source and system. The structure of nozzle is one of the main factors that influence the performance of the SOPJ nozzle. Upper collapse wall and lower collapse wall is important to the formation a... |
This paper concerns the application of a NPC three-level shunt active power filter for damping harmonic disturbances from a three-phase feeder. The main contribution of the article is the elaboration of an algorithm dedicated to manage the energy in the hybrid fuel cell/battery DC bus feeding the SAPF. Design of active... |
Transforming growth factor-beta (TGF-β) is a growth-regulating peptide that has been shown to enhance collagen production both in vivo and in vitro. The previous studies demonstrated that TGF-β 1 is present in the normal animal myocardium. However, the expression and localization of TGF-β 1 and TGF-P receptor in human ... |
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