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METHODS |
Heparanase and NF-kappaB p65 proteins in the tumor and adjacent tissues were detected by immunohistochemistry in 48 patients with pancreatic adenocarcinoma and analyzed for their clinicopathological significance. |
RESULTS |
Heparanase and NF-kappaB p65 proteins were found in 30 (62.5%) and 22 (45.9%) tumor specimens, respectively, a rate significantly higher than that in the adjacent tissues. High heparanase expression was closely related to advanced TNM stage (P=0.031), lymph node metastasis (P=0.003) and decreased 3-year postoperative s... |
CONCLUSION |
Heparanase is overexpressed in pancreatic adenocarcinomas in association with decreased postoperative survival. NF-kappaB may up-regulate heparanase expression and promote heparanase-dependent tumor invasion and metastasis.High frequency penetrating radar data interpretation by means of joint time frequency analysis |
A processing technique able to enhance the range resolution attainable through a continuous wave step frequency (CW-SF) radar on layered structures of few centimeters behind tens of centimeters masonry was tested on experimental data. The technique is based on joint time frequency analysis (JFTA). The simulated signal ... |
Abstract Background: The features of migraine attacks and the contexts in which migraine attacks occur vary from attack to attack and from patient to patient. Current treatment strategies, which are dominated by the use of oral forms of migraine medication, do not address this patient-to-patient and attack-to-attack he... |
LEVEL OF EVIDENCE: 3b SUMMARY Background. Downhill mountain biking (DMB) is a subdiscipline of mountain biking. Rider skill seems to be the most influencing variable for DMB performance. In order to classify skill level, the aim of the present study was to investigate DMB-participants in terms of accident involvement, ... |
SIR: I recommend your UNIFAC calculations be reevaluated because of two statements ( I ) : (1) “UNIFAC predicted the y (activity coefficient) for biphenyl to be greater than that of decachlorobiphenyl” and (2) “UNIFAC yielded very inaccurate y’s for all the compounds.” I calculate log y for biphenyl to be 6.025 and 15.... |
Since asthma is the most common noncommunicable chronic childhood disease in the United States, school nurses will encounter students with this health condition. The purpose of this article is to present the school nurse as the leader in directing the management of a student’s chronic health condition at school. This a... |
Congenital toxoplasmosis is a neglected protozoonotic disease of intercontinental distribution with incidence estimated in 1.5 cases per 1000 live births. This infection can be acquired intrauterine when the first infection of pregnant woman occurs and the Toxoplasma gondii reaches the fetus by transplacental via. The ... |
Both platelet aggregation and high blood pressure are associated with development of atherosclerosis. Among other factors that modulate platelet aggregation and blood pressure, extracellular purines (e-purines) influence these processes via purinoceptors P1 and P2 for which they are natural ligands. We hypothesized tha... |
This article examines the information war between NATO and Serbia that accompanied the ?liberation? of Kosovo in 1999. In the light of popular readings of Vietnam and the Gulf, as the first television and satellite wars, it suggests Kosovo is the first web war. While accepting that the web in 1999 could not be understo... |
From the environment surrounding us, there are different sounds, noises as physical waves, which are arriving to the living organism. These dissonant and consonant inputs have a negative or a positive effect on the quality of life, respectively. The noise, as a dissonant sound has always a negative effect, while music,... |
OBJECTIVE |
To characterize signalment, clinical signs of disease, and clinical response to insulin in equids with hypertriglyceridemia. |
DESIGN |
Retrospective case series. |
ANIMALS |
20 horses, 17 ponies, and 7 donkeys with hypertriglyceridemia. |
PROCEDURES |
For analysis of medical record data, horses, donkeys, and ponies with multiple serum or plasma triglycerides measurements were separated into groups. Hypertriglyceridemic equids that were (HT-I; n = 14) or were not (HT-N; 10) treated with insulin consisted of equids with an initial triglycerides concentration > 44 mg/d... |
RESULTS |
No age predilection for hypertriglyceridemia was apparent. Of the 29 female equids, only 7 (24%) were lactating or pregnant. Multiple illnesses were diagnosed in hypertriglyceridemic equids, including colitis (14/44; 32%) and colic (9/44; 20%). Many breeds were affected, including 16 (36%) American Miniature Horses and... |
CONCLUSIONS AND CLINICAL RELEVANCE |
Equids of all ages and sexes with various diseases had hypertriglyceridemia. Insulin treatment decreased the triglycerides concentrations in affected equids.An electrophysiological study on the effect of laser irradiation of round window membrane in the guinea pig. |
An argon laser beam was used to irradiate the round window in 17 guinea pigs. Each animal was examined electrophysiologically with an electrode placed on the round window (RW) membrane 3 or 30 days after the irradiation, after which the cochlea was examined morphologically. The RW membrane was found intact in 16 out of... |
The main objective of the current study was to investigate the in vitro and in vivo antidiabetic activity of methanol extracts Carthamus oxyacantha leaves and corollas. In vitro antidiabetic assays such as inhibition of α-amylase enzyme, non-enzymatic glycosylation of hemoglobin and glucose uptake in yeast cells were ... |
The question of how and when liability attaches is one of the most important issues facing volunteer organizations today. The liability issue has three related components: (1) whether the organization is liable to third parties for acts performed by volunteers, (2) whether the organization is liable to volunteers who a... |
Background Previous clinical trials indicate that probiotic consumption may improve blood glucose control, however, results from randomized trials on glycemic control have been inconsistent. Objective To investigate the effects of probiotics on glycemic control in a systematic review and meta-analysis of randomized con... |
Let μ be a positive measure on R d and let F(μ) = {P(θ, μ); θ ∈ Θ} be the natural exponential family generated by μ. The aim of this paper is to show that if μ is infinitely divisible then the generalized variance of μ, i.e., the determinant of the covariance operator of P(θ, μ), is the Laplace transform of some positi... |
Students' questions are essential to help teachers in assessing their understanding and adapting their pedagogy. However, in a flipped classroom context where many questions are asked online to be addressed in class, selecting questions can be difficult for teachers. To help them in this task, we present here three alt... |
Computational seismology is an area of wide sociological and economic impact, ranging from earthquake risk assessment to subsurface imaging and oil and gas exploration. At the core of these simulations is the modeling of wave propagation in a complex medium. Here we report on the extension of the high-order finite-elem... |
In magnetic resonance (MR), hardware limitation, scanning time, and patient comfort often result in the acquisition of anisotropic 3-D MR images. Enhancing image resolution is desired but has been very challenging in medical image processing. Super resolution reconstruction based on sparse representation and overcomple... |
Microbial keratitis (MK) is a vision-threatening disease and the fourth leading cause of blindness worldwide. In this work, we aim to develop moxifloxacin (MXN)-loaded chitosan-based cationic mucoadhesive polyelectrolyte nanocapsules (PENs) for the effective treatment of MK. PENs were formulated by polyelectrolyte comp... |
Here, the impacts of biogas power plants and photovoltaic (PV) power plants on the power quality in the distribution network are presented and analysed. The biogas power plant's influence on the current harmonics is explored, as a synchronous generator powers the biogas power plant, and the PV plants are connected to t... |
The paper deals with design process of a force measuring unit, which is capable to mount onto a robot or to integrate into a measuring device. The main element is a beam type load cell equipped with strain gauges in Wheatstone bridge configuration. In order to measure the force only in one direction a linear guide rail... |
Our recent studies demonstrated that extracellular signal‐regulated kinase (ERK) played an important role in the regulation of vascular contractility of ovine uterine arteries. In addition, pregnancy significantly increased ERK protein and mRNA levels in the uterine artery. In an effort of attempting to study the regul... |
The performance of AlGaN/GaN high-electron mobility transistors that were passivated with AlSiN and SiN and fabricated side by side has been studied. It is found that the AlSiN passivation produced state-of-the-art devices, improving both small- and large-signal performance over the SiN passivation, particularly at hig... |
Pipelining is a widely used technique for implementing architectures which have inherent temporal parallelism when there is an operational requirement for high throughput. Many variations on the basic theme have been proposed, with varying degrees of success. The aims of this paper are twofold. The first is to present ... |
The iron loss of industrial motors increases by residual stress during manufacturing processes. It is very important to make clear the distribution of the residual stress in the motor cores to reduce the iron loss in the motors. Barkhausen signals which occur on electrical steel sheets can be used for the evaluation of... |
This is a short book, based on Nesbitt's PhD thesis, which describes the technical and ideological forces that led to the Social Security Act 1986 and the introduction of contracted-out personal pensions following Norman Fowler's 1983 Inquiry into Provision for Retirement. The book begins with an outline of pensions po... |
struggle for establishing an independent state, Russia has managed to compromise both’ (p. 273). Although the state has thus far proven to be more durable than democracy, there are still limits to the state project that work against the establishment of fully-fledged authoritarian rule. Bunce’s consequent claim of an ‘... |
Experimental evidences were presented to show induction by cancer chemotherapeutic agents of terminal differentiation of several cultured myeloid leukemia cell lines and fresh leukemia cells from patients with myelogenous leukemia. A description was also given of recent clinical trials to improve the therapy of patient... |
List of figures List of tables Preface Acknowledgements Part I. Theoretical Foundations: 1. Cross-situational consistency: an issue at the interface between personality and social psychology 2. The history of the consistency debate 3. P x S: the promise of modern interactionism 4. The cognitive representation of situat... |
Background The Health Survey for England (HSE) is a general health survey administered annually to a probability sample of people living in England. In 2010, the HSE included, for the first time, questions about sexual health, which previously were considered too sensitive for a general health survey. This paper compar... |
The effects of gestational age at delivery (GA), postnatal age (PNA) and post-menstrual age (PMA=PNA+GA, an indicator of autonomous developmental processes not affected by the moment of birth) on macronutrient composition of very preterm milk were studied. Total N, fat, lactose and carbohydrate concentrations, energy d... |
The modification of computer programs is a costly and constant job. An informal survey conducted at General Motors and reported on by Elshoff [6] concluded that about 75 percent of all programmer/analysts' time in a commercial data processing installation is spent on program modification. This conclusion agrees with in... |
Efficiency and tolerance of the Vena Tech-LGM filter were assessed in 142 patients prospectively studied during a 2-6-year follow-up period. No patients were lost to follow-up, and 137 (91.3%) scheduled control examinations were performed. Fifty-three patients died of causes unrelated to thromboembolic disease. Pulmona... |
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