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BACKGROUND |
It is still difficult to define the biochemical mechanisms that cause alterations in neuronal function and plasticity and neuronal cell loss in the brains of alcohol-dependent patients. |
METHODS |
To evaluate the extent of cerebral alcohol-induced oxidative stress ex vivo, we investigated the levels of glutathione (GSH), its oxidation product glutathione disulfide (GSSG, produced by GSH-peroxidases), and the activities of catalase and superoxide dismutases (SOD). In addition, selected brain regions from up to 22... |
RESULTS |
The most prominent findings showed significantly decreased GSH/(GSH+2GSSG) molar redox (oxidation-reduction) ratios in the corpus mamillare and cerebellum, which appeared due to an increase in GSSG caused by chronic alcohol intake. Catalase activity was increased in only the frontal cortex, whereas decreased catalase a... |
CONCLUSIONS |
We propose that decreased brain GSH/(GSH+2GSSG) molar redox (oxidation-reduction) ratios in alcohol-dependent patients may reflect neural impairment due to increased peroxide production after chronic alcohol consumption. However, future experiments, investigating the activities of enzymes and cofactors involved in GSH ... |
The relative stabilities of the nine possible isomers for C80O based on C80(D5d) were investigated via density function theory (DFT) at B3LYP/6-31G(d) level. The most stable geometry of C80O is predicted to be 23,24-C80O, where an annulene-like structure is formed. The stretching vibration frequencies of the C=C bonds ... |
ABSTRACT This article is a summary of ‘Creating Positive Spaces by Designing for Community’ in which we present research on the psychological benefits of a sense of community and how these benefits can be harnessed in workplace design (specifically within offices) to improve business outcomes. Here, we summarise this r... |
Compulsion is one of core symptoms of obsessive-compulsive disorder (OCD). Although many studies have investigated the neural mechanism of compulsion, no study has used brain-based measures to predict compulsion. Here, we used connectome-based predictive modeling (CPM) to identify networks that could predict the levels... |
The paper's object is to develop a smart home automation system with sustainable renewable energy. The paper presents a conceptualization and implementation of developing a smart home system that uses solar panels to maximize the use of abundant renewable energy. This system is created to minimize the carbon footprint ... |
The concentration polarization phenomena and its effects represent one of the main challenges for the optimal operation of many nanofluidic systems. A numerical investigation of the different electric current transition regimes observed during the concentration polarization phenomena in nanochannels is performed. This ... |
In this paper, the cosmic microwave background (CMB) anisotropy in a multiply connected compact flat 3-torus model with the cosmological constant is investigated. Using the COBE-DMR four-year data, a full Bayesian analysis revealed that the constraint on the topology of the flat 3-torus model with low matter density is... |
The effects of intraperitoneal CO2 insufflation on middle cerebral arterial blood flow velocity were evaluated in 10 patients undergoing laparoscopic cholecystectomy under general anesthesia with nitrous oxide, oxygen, and isoflurane. Blood flow velocity was measured using transcranial Doppler ultrasonography. During C... |
Left ventricular assist device (LVAD) is one of the modern management therapies in patients with advanced heart failure, and it serves as a bridge to heart transplantation or even as destination therapy. However, it is burdened with a high risk of thromboembolic, hemorrhagic, and infectious complications despite prophy... |
The effect of three iodinated contrast media (CM) on human plasma butyrylcholinesterase (BuChE) activity was studied during the intravenous pyelography (i.v.P). BuChE is an enzyme that participates in the metabolism of acetylcholine and hydrolyzes food esters and drugs such as nondepolarizing muscle relaxants and local... |
The records of 583 children who were treated for intussusception at the Children's Hospital of Buffalo in the period 1930-1985 were reviewed. Following a change in management in 1970 from operative treatment to hydrostatic reduction of the intussusception by barium enema, two main groups are defined. In earlier years 9... |
Relationships of the somatic antigens among Clostridium botulinum strains have been investigated by tube agglutination and agglutinin absorption tests. Results revealed a relationship by which strains of C. botulinum are grouped by their proteolytic capacity rather than by the type of specific toxin produced. Thus, C. ... |
In this paper, we analyzed a spectrum of the SMPS (Switching Mode Power Supply) which uses DPWM (Digital Pulse Width Modulation) and adopts SSC (Spread Spectrum Clocking) circuit to reduce EMI (Electro-Magnetic Interference) noise. Generally, SSC circuits are used in order to reduce noise peaks by spreading switching f... |
ABSTRACT More than 60% of species examined from a total of 421 strains of heterotrophic marine bacteria which were isolated from marine sponges and seawater were observed to have no detectable siderophore production even when Fe(III) was present in the culture medium at a concentration of 1.0 pM. The growth of one such... |
The veriication of multi agent systems is an important and diicult task. Though much work is spent on veriication in concurrency theory only few results and tools are used in multi-agent systems. In this paper, we investigate how CCS, the calculus for concurrent systems, may contribute to the veriication of multi-agent... |
An esterase gene (estC) was isolated from a genomic library of Lactobacillus casei LILA. The estC gene consisted of a 777 bp open reading frame encoding a putative peptide of 28.9 kDa. A recombinant EstC fusion protein containing a C-terminal six-histidine tag was constructed and purified to electrophoretic homogeneity... |
Frequent item set mining is an important data mining method with many real-life applications. This paper presents a new frequent item set mining algorithm based on interval intersection. For each item set in the mining dataset, an interval set is used to keep track of the transactions that contain this item set. Interv... |
The paper describes recent results of theoretical and experimental studies of novel schemes of FEM-oscillator and amplifiers carried out in collaboration between JINR (Dunba) and IAP RAS (N. Novgorod) based on induction linac LIU-3000 0.8 MeV / 200 A / 200 ns and aimed on topical applications, including accelerating an... |
In this work we report a design, synthesis, and detailed functional characterization of unique strongly biased allosteric agonists of CXCR3 that contain tetrahydroisoquinoline carboxamide cores. Compound 11 (FAUC1036) is the first strongly biased allosteric agonist of CXCR3 that selectively induces weak chemotaxis and ... |
The SC organizational structure, and related management policies, is a crucial factor that can be adjusted to improve the SC performance, which consequently has to be taken into account in the SC modeling and simulation. This paper addresses a new methodological framework in the context of an agent-based SC simulation,... |
E lectroconvulsive therapy (ECT) is an effective and safe treatment for depression especially in late life. Melancholia's unique features include but not limited to lack of mood reactivity, mood worse in mornings, early morning awakening, psychomotor agitation or retardation, excess guilt, and weight loss. Psychotic de... |
Although anaesthetic techniques are well established for most of the vertebrates, methods for the invertebrates are generally not well documented. The decapod Crustacea are widely used for neurophysiological studies involving the implant of chronic electrodes and other techniques. With sluggish species such as Cancer p... |
Immunotoxins comprise a new class of cell-type specific cytotoxic reagents which consist of a monoclonal antibody linked to a protein toxin. This report examines the efficacy of intrathecal immunotoxin therapy for the treatment of tumors of the cerebrospinal fluid compartment. A syngeneic animal model of leptomeningeal... |
Three commercially available adjuvants--incomplete Freund's, Ribi adjuvant system, and Hunter's TiterMax--were used to compare antibody responses of broilers to Pasteurella multocida antigen. Differences among treatments over the 9-week study were determined by measuring antibody responses of twice-vaccinated birds usi... |
ABSTRACT People have different moods that vary in different spaces, and the “light” is one of the most important factors affecting the mood of people in an indoor environment. Conducted with 50 volunteers using a church design in the virtual reality environment, the study aims to test individuals’ mood changes in the d... |
Objective: The purpose of this study was to determine the knee and ankle joint kinematics and kinetics by comparing downhill walking with valley-shape combined slope walking. Method: Eighteen healthy men participated in this study. A three-dimensional motion capture system equipped with eight infrared cameras and a syn... |
In this thesis, we address the issue of fully localizing a known object through computer vision, using a monocular camera, what is a central problem in robotics. A particular attention is here paid on space robotics applications, with the aims of providing a unified visual localization system for autonomous navigation ... |
OBJECTIVES |
An earlier study of workers in fish-fillet plants in Iceland showed higher prevalence of musculoskeletal symptoms as compared to a random sample of the Icelandic population. Since that study a new manufacturing process, the flow-line, has been introduced. The aim of this study was to evaluate whether this new work situ... |
MATERIAL AND METHODS |
The same standardised Nordic Questionnaire was used in both surveys. |
RESULTS |
The monotony and the repetitiveness of the work increased with the new technique. The results showed that women had higher prevalence of symptoms of the upper limbs when working at the flow-line than before. The Mantel-Haenszel odds ratio for symptoms of elbows, fingers and wrists during the last seven days prior to th... |
CONCLUSIONS |
The higher prevalence of symptoms of the upper limbs seems to be causally related to the increase of monotonous and repetitive work in the fish industry.[The treatment of ureteroceles complicated by calculi]. |
In a series of 13 adults with calculi in ureteroceles, 10 cases underwent endoscopic meatotomy associated with endoscopic lithotripsy. In 2 bulky ureteroceles with calculi, the authors performed excision of the ureterocele and reimplantation of the ureter. In one case, the authors successfully performed extracorporeal ... |
Combinatorial increases in programming productivity are possible by the introduction of high level ope rators and operands for composite data structures such as arrays, matrices, trees, record composites, etc. Su ch operators and operands can be composed to generate an infinite variety of virtual reusable components. H... |
One major field of study in the Graduate School of Management at UCLA is in Computers and Information Systems (CIS). This major has evolved from a single course on Electronic Computers in Business introduced in 1957 to one with more than a dozen courses devoted to some aspect of education about computers and informatio... |
In neural stimulation, a current mode stimulation is preferred to a voltage mode stimulation, as it has more control over injecting charge into tissue. A matched biphasic current pulse is often employed in current mode stimulation. For safe neural stimulation, in other words, to ensure zero-net charge transfer (charge ... |
The self-assembled type-II GaSb quantum dots (QDs) were successfully grown on semi-insulting GaAs (100) substrate by the liquid phase epitaxy (LPE) technique with growth temperature ranging from 520 to 580 oC. The morphology of GaSb QDs including size, shape and density was investigated by atomic force microscopy measu... |
In this paper, a novel breath-analyzer has been proposed for the detection of human breath-specific bio-markers. A metal-graphene stacked nanostructured metamaterial has been designed and optimized to maximize the light intensity absorption based on the phenomenon of surface plasmon resonance (SPR). The sub-wavelength ... |
Five diagnostically problematic spindle cell sarcomas showing invasive character, cellular pleomorphism, and high mitotic rate were studied clinically and histopathologically by conventional light microscopy, immunohistochemistry, and transmission electron microscopy. They showed varied clinical courses, with two causi... |
: Urban spatial cognition is a classic research topic of behavioral geography. In this study, we selected the main urban districts of Beijing and investigated the spatial cognition of graduate students of the University of Chinese Academy of Sciences using a combination of methods of cognitive map and questionnaire sur... |
Large-caliber gun barrels are coated, on their internal surface, by hard and refractory metallic layers. The thermophysical properties of such coatings are generally very different of bulk materials ones, and liable to evolve following the thermal cyclings. Nevertheless, the knowledge of these properties is necessary f... |
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