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Frozen-dried preparations were studied for the impact of moisture content of the nuclear magnetic resonance parameter that was a ratio of the amplitudes of a slow component and a rapid one of a free induction signal from the protons of samples. It was found that there was a linear correlation between this parameter and... |
This paper presents efficient integer-pel and fractional-pel motion estimation VLSI architectures for luma video component in H.264/AVC. The proposed architectures were designed as hardware accelerators for 32-bit processors to reduce computation cost and processing time. Both accelerators use the full-search block-mat... |
BACKGROUND & AIMS |
To explore mechanisms whereby acid reflux might contribute to carcinogenesis in Barrett's esophagus (BE) we studied: (1) the effects of acid on the mitogen-activated protein kinase (MAPK) pathways, cell proliferation, and apoptosis in a Barrett's adenocarcinoma cell line (SEG-1); and (2) the ability of acid to activate... |
METHODS |
SEG-1 cells were exposed to acidic media for 3 minutes, and the activities of 3 MAPKs (ERK, p38, and JNK) were determined. Proliferation was assessed using flow cytometry; cell growth and apoptosis were assessed using cell counts and an apoptosis ELISA assay. MAPK activation was studied in biopsy specimens taken from p... |
RESULTS |
Acid-exposed SEG-1 cells exhibited a significant increase in proliferation and total cell numbers, and a significant decrease in apoptosis. These effects were preceded by a rapid increase in the activities of ERK and p38, and a delayed increase in JNK activity. PD 98059 abolished the acid-induced increase in G0/G1 and ... |
CONCLUSIONS |
Acid increases proliferation and survival, and decreases apoptosis in SEG-1 cells by activating the MAPK pathways. Acid also activates the MAPK pathways in BE in vivo. These findings suggest that acid might contribute to carcinogenesis in BE through activation of MAPK pathways.Osseointegration Foundation Charity Overde... |
This investigation has been stimulated by the Osseointegration Foundation, working in conjunction with the Zest Anchors implant company. There are three basic valuable activities that emerge from a professional foundation, which were reflected in this case study. They include disseminating information to practitioners,... |
Most non-conductive materials and non-polar liquids are transparent to terahertz frequencies (0.2–2THz), and due to their non-ionizing photon energies there is great interest and potential in imaging in the THz regime [1]. However, the long wavelengths (1.5–0.15mm) mean that even diffraction limited imaging will fail t... |
A major objective of the TAT-8 submarine cable development program is the reliability assurance of its critical components. A relatively new device, the InGaAs photodiode, is used as the detection element in optical receivers and as the monitor of laser output in optical transmitters. In this paper, we describe a compr... |
This study presents an analysis of an existing biogas engines-powered cogeneration system installed in Varna Wastewater Treatment Plant, Bulgaria using thermoeconomic method. The thermoeconomic analysis is conducted using three different groups of environmental conditions. The SPECO (specific exergy cost) method is app... |
Badger luteal tissue fragments harvested and cultivated during the inactive phase do not resemble active corpus luteum as do granulosa cells in vitro. Production of oestrogen and progesterone by these fragments was examined. Amounts produced are much smaller than in the case of granulosa cells and are slightly influenc... |
A central component of the human self is the narrative history of shared interactions with others, which provides the foundation for social relations that develop over extended time. The loss of this narrative self progressively becomes catastrophic for aging subjects with degenerative disease of the memory system. A p... |
There are considerable uncertainties around the definition and the appropriate clinical diagnostic criteria for gastro‐oesophageal reflux disease (GERD), a common condition that appears to be increasing in prevalence in the Western world. Prevalence studies of GERD are hampered by whether any heartburn symptom is inclu... |
Disclaimer: These notes are intended to be an accessible introduction to the subject, with no pretense at completeness. In general, you can find more thorough discussions in Oppenheim's book. Please let me know if you find any typos. In this lecture, we discuss how the poles and zeros of a rational Z-transform H(z) com... |
Abstract Atypical antipsychotic risperidone is widely used first-line monotherapy in schizophrenia and combined therapy in bipolar disorders. Therapeutic plasma concentrations of risperidone and its active moiety are directly influenced by genetic variations in metabolic CYP450 enzymes (CYP2D6 and CYP3A4/5) and transpo... |
Abstract Objective. To study serum infliximab (s-IFX) levels in pediatric patients with inflammatory bowel disease (IBD). Subjects and methods. s-IFX trough levels were measured in a total of 133 blood samples of 37 pediatric IBD patients (Crohn's disease, 23): 48 during the induction phase (weeks 2 and 6) and 85 durin... |
In order to evaluate whether glucagon-induced hyperkalemia is due to mobilization of potassium from the splanchnic region, we measured potassium changes in the hepatic veins following a glucagon injection into the ascending aorta. Twenty-seven subjects undergoing routine cardiac catheterization for diagnostic purposes ... |
The McCarthy Scales of Children's Abilities (MSCA) were factor analyzed at five age levels: 2½, 3-3½, 4-4½, 5-5½, and 6½-7½-8½. The standardization sample (N = 1032) provided the source of data. Varimax rotated factors akin to four of the six MSCA Scales— General Cognitive, Verbal, Memory, and Motor—appeared at age 2½,... |
SUMMARY Women's voices, roles, and contributions are die most misunderstood issues in the analysis of war zones and conflict areas. This paper brings the feminist lens into the analysis of Israeli policies in the Occupied Palestinian Territories. It examines the effect and legacy of policies inflicted by the doctrines ... |
There are numerous arithmetical puzzles concerning the quantities of beer that can be measured if the only available measures are a 3-pint jug and a 5-pint jug, or the exact amounts of money obtainable using only 3p and 5p coins, or the amounts that can be made with only 3p and 5p stamps.Semi-Analytical Solution for Un... |
The effect of different initial degrees of saturation on the behaviour of variably saturated soils around an expanding cavity has not been adequately studied thus far. Therefore, this study aims to fill this gap. Moreover, it seeks to theoretically explain the cylindrical cavity expansion response in unsaturated three-... |
Abstract Twenty-six lignite samples, from eleven different basins of Greece, were examined as a precursor material to produce activated carbons. Two different experimental procedures were compared, a physical one, using CO2 as the activation agent after carbonization in N2, and a chemical one where lignites impregnated... |
Molecular communication is a pioneering paradigm focusing on the communication between nano- and micro-scale machines, encompassing various novel communication systems. Currently, most of the studies in the literature regarding these systems focus on single transmitter single receiver topologies. However, in a more rea... |
This paper will consist of a discussion of how a classroom aquatic ecosystem can serve as an educational tool to enhance the synthesis of Earth Science Systems concepts to benefit a high school curriculum. Including what students can learn from a classroom aquatic ecosystem in terms of wastewater treatment processes, a... |
Abstract This paper proposes a simplified approach for assessing and predicting the seismic risks for electrical cabinets in nuclear power plants (NPPs). The method is a combination of fragility analysis and cumulative absolute velocity (CAV) analysis. First, the high confidence of low probability of failure points fro... |
In this paper, the use of the Dual Kalman Filter for the identification of photovoltaic system parameters is presented. The system includes the photovoltaic source, the dc/dc converter and the battery/dc bus and both its states and parameters in the actual operating conditions are identified. In particular, the propose... |
Fear of falling is a well-known condition in later life. The aim of this study was to illuminate the experiences and the meaning of fear of falling in a daily-life context. The method used was a qualitative study inspired by interpretive phenomenology. In narrative interviews, five community-dwelling women over 80 year... |
This research aimed at describing the advantages of android use in learning process. This research conducted at the fourth semester of English Department of Education and Teachers Training Faculty of Universitas Lancang Kuning. The sample of this research is 30 % of the total number of the population, they are about 7 ... |
Nanometric technologies is the way for the realization of numerical structures of considerable size gathering several hundreds of million transistors on one chip. This miniaturization makes manufacturing processes more complex and less reliable. By consequence, the output of manufacture is likely to drop considerably. ... |
Obstructive disorders of the salivary glands usually manifest as a swelling which is associated with meals ('mealtime syndrome') as well as inflammation of the gland. Obstruction of the salivary ducts of the parotid and submandibular glands is usually caused by a salivary stone, mucous plug or by a stenosis. Until rece... |
Michael L. Steer 1939–2019 D r. Michael Lewis Steer (born June 26, 1939) died of complications related to colon cancer on April 18, 2019, at the age of 79 years. He was a prominent surgeon/ scientist in the pancreas field and a pioneer in the cell biology of pancreatitis. Mike Steer was born in Brooklyn, New York, the ... |
In this paper, Ta/Mo interdiffusion dual metal-gate technology, which has an advantage in realizing dual gate work functions without etching of metals from the gate dielectrics, has been introduced for a FinFET. Gate-first fabrication of the FinFET was successfully implemented by optimizing the deposition and patternin... |
Industrial, military, medical, and research and development applications of lasers frequently require a beam with a specified irradiance distribution in some plane. A common requirement is a laser profile that is uniform over some cross-section. Such applications include laser/material processing, laser material intera... |
How teachers think about student thinking informs the ways in which teachers teach. By examining teachers' anticipation of student thinking we can begin to unpack the assumptions teachers make about teaching and learning. Using a "mathematics for teaching" framework, this research examines and compares the sorts of ass... |
To evaluate the effects of various barbiturates on lidocaine metabolism by cytochrome P-450 (P-450), enzyme kinetics were analyzed in an in vitro study using rat hepatic microsomes. Phenobarbital, amobarbital, hexobarbital, pentobarbital, and thiamylal showed the mixed type inhibition of lidocaine metabolism with inhib... |
Split FOV (Field of View) star tracker was developed by Texas A&M University together with the University of Rome “La Sapienza”. A 50% splitter was used to combine light beams from two separate FOVs, while only a single objective lens and optical detector are used. In this way, double FOV configuration allows increased... |
In [2] we dealt with the concept of normal Agassiz system of algebras being a modification of Agassiz system introduced by G. Gratzer and J. Sichler in [1]. Now we want to discuss a generalization of the concept of normal Agassiz system in the direction suggested by the definition of naming functor given by Gratzer and... |
Abstract A novel class of chemiluminescent, chemical sensors are described which are based upon the immobilization of a chemiluminescent reagent, luminol or tris(2,2′-bipyridyl)ruthenium(III) (Ru(bpy) 3 3+ ), between a miniature photomultiplier tube and a teflon diffusion membrane. The membrane serves to separate the c... |
Because of the refractory nature of mutant KRAS lung adenocarcinoma (LUAD) to current therapies, identification of new molecular targets is essential. Genes with a prognostic role in mutant KRAS LUAD have proven to be potential molecular targets for therapeutic development. Here we determine the clinical, functional, a... |
Objectives: This study was conducted to evaluate tinzaparin dosing and therapeutic drug monitoring. Design: Retrospective study. Setting: Single tertiary-level PICU. Patients: Tinzaparin doses and anti-Xa levels from all children admitted to a PICU (from October 1, 2010, to December 31, 2013) were retrospectively analy... |
Cementoossifying fibroma of the maxilla is an uncommon tumor. Lesions with fibrous and osseous components include fibrous dysplasia (FD), ossifying fibroma (OF), cementoossifying fibroma (COF) and cementifying fibroma (CF). Fibro-osseous lesions other than FD seem to arise from the periodontal membrane. We present a cl... |
In today many students produce a wrong and illegible handwriting and teachers need a lot of time to check the handwriting errors. The traditional approach for handwriting teaching needs a long hours of handwriting practice. Unfortunately, this is not advantageous in many cases. In this paper, we develop an automated ed... |
It has been evident for some time that individuals from some families exhibit a genetic predisposition to breast cancer. Since the discovery of the first breast cancer susceptibility gene, BRCA1 in the 1990s, much work has been carried out to identify further breast cancer susceptibility genes. This has led to the iden... |
This in vitro study aimed to investigate the whitening efficacy of 940 nm and 980 nm diode laser photoactivation in tooth bleaching by analysing pulp chamber temperature, as well as the change in tooth colour. Root canals of thirty extracted human lower premolars were prepared. Laserwhite* 20 bleaching agent containing... |
Abstract A group of 33 controllers of an emergency service were studied before and after a change in shift roster. The original roster was the traditional weekly rotating type of three shifts, morning, afternoon and night in that direction, in which controllers worked seven consecutive shifts of the same type. This was... |
To advance the development of point-of-care technology (POCT), the National Institute of Biomedical Imaging and Bioengineering established the POCT Research Network (POCTRN), comprised of Centers that emphasize multidisciplinary partnerships and close facilitation to move technologies from an early stage of development... |
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