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A near-maximum-likelihood (ML) detection algorithm for spatially multiplexed multiple-input multiple-output (MIMO) systems has been considered. The sphere decoder (SD) is one of the promising techniques to solve the ML problem. However the SD has a loose necessary condition for pruning branches, and it becomes impracti... |
INTRODUCTION |
Dopamine (DA) plays a key role in different aspects of the male sexual response, including sexual motivation and arousal, penile erection, and ejaculation. The modalities of action of DA are however unclear, although the various DA receptors may differentially mediate the activity of DA in different aspects of the male... |
AIM |
To clarify the role of DA D(3) receptors in the control of the male sexual response. |
METHODS |
The effects of a highly selective DA D(3) receptors antagonist (SB-277011; intraperitoneal) were tested in experimental paradigms exploring several aspects of the male sexual response in (i) anesthetized rats using 7-hydroxy-N,N-di-n-propylaminotetralin to induce ejaculation and (ii) conscious rats using sexual incenti... |
MAIN OUTCOME MEASURES |
Physiological markers of erection and emission and expulsion phases of ejaculation were measured in anesthetized rats. Behavioral parameters of sexual incentive motivation and mating tests were quantified. |
RESULTS |
In anesthetized rats, we found that SB-277011 specifically and dose-dependently inhibited the expulsion phase of ejaculation without impairing either emission phase or erection, and this resulted in delayed ejaculation. Administration of SB-277011 had no effect on the spontaneous preference that males displayed for sex... |
CONCLUSION |
As a whole, the present data demonstrate the specific and primary role of D(3) receptors in the expulsion phase of ejaculation and provide preclinical evidence for the investigation of the therapeutic potential of D(3) antagonism for treating premature ejaculation.Identifying Risk for Attrition during Treatment for Dep... |
Background: Understanding patients’ ambivalence about treatment persistence may be useful in tailoring retention interventions for individual patients with major depressive disorder. Methods: Participants (n = 265) with major depressive disorder were enrolled into an 8-week trial with a selective serotonin reuptake inh... |
People who work collaboratively often review each other's work. They may do so by annotating work artifacts, such as documents. People seeking to understand annotated artifacts confront two problems. Clutter occurs when people see an overwhelming number of annotations. Clutter is a well-studied problem, whose solution ... |
We are particularly interested in annotation of software artifacts, which is a common task in software development. We introduce a three-dimensional taxonomy for delocalization within software systems: lateral delocalization (between items of the artifact within the same development phase), longitudinal delocalization ... |
Annotation is a vital part of software inspection, which is a well-known means of software quality improvement. We discuss how to address delocalization within software inspection. We describe the development and use of AnnoSpec, a software inspection toot supporting clutter reduction and visibility of delocalized anno... |
The science of wave‐field phase retrieval and phase measurement is sufficiently mature to permit the routine reconstruction, over a given plane, of the complex wave‐function associated with certain coherent forward‐propagating scalar wave‐fields. This reconstruction gives total knowledge of the information that has bee... |
Objectives |
EFNEP helps low-income audiences acquire the knowledge and skills necessary to plan, procure, and prepare nutritionally sound diets. The study objective was to determine EFNEP participants' change in HEI-2005 scores in 2013-2014. |
Methods |
This study was a secondary analysis of the 24 hour recall (24HR) data collected from EFNEP participants from October 2012 - September 2014. EFNEP staff entered entry/exit 24HR data into a web-based data evaluation program using the Food and Nutrient Database for Dietary Studies (version 3.0). Initial data set (n = 135,... |
Results |
The mean (sd) HEI scores were 51.1 (13.7) at entry and 56.5 (13.7) at exit, with a change of 5.4 (16.7) after completion of the program (P < 0.05); nine of 12 component scores increased. The change in HEI-2005 scores was significantly greater as age increased, with increasing education, and in women. Thirty-two % of th... |
Conclusions |
The results reported here are the first known national documentation of change in HEI dietary quality due to EFNEP participation. Results indicate that EFNEP participation improves diet quality based on change in HEI-2005. This improvement was evident in nine of 12 HEI-2005 components and across all demographic charact... |
Funding Sources |
Agriculture Experiment Station NC2169: EFNEP Related Research, Program Evaluation and Outreach. |
Supporting Tables Images and/or GraphsOn Completeness of Knowledge Models |
We study knowledge models in which the set of states of nature is equipped with a countable algebra of subsets. We show that a complete knowledge model based on such a state space exists, when knowledge is modeled by knowledge operators. We show also that types in such a model have a non-circular, type-independent char... |
We report on a 52-year-old woman with a pure rhabdomyosarcoma of the corpus uteri. Histopathological study revealed that the tumor was composed only of rhabdomyosarcoma (RMS) and it was not associated with carcinoma or other elements of mixed mesodermal tumor. An undifferentiated tumor element was observed. Using the i... |
Abstract A very rare case of a sebaceous carcinoma of the external auditory canal with basal cell differentiation is presented. Fewer than 400 cases affecting any part of the body have so far been reported and of that only seven cases have been known to involve the external auditory canal. The clinical features, pathol... |
The objective of this article is to investigate the problems related to the extensional integration of information sources. In particular, we propose an approach for managing inconsistent databases, that is, databases violating integrity constraints. The problem of dealing with inconsistent information has recently ass... |
Background: The responsible genes have not yet been identified for many genetically mapped disease loci. Physically interacting proteins tend to be involved in the same cellular process, and mutations in their genes may lead to similar disease phenotypes. Objective: To investigate whether protein–protein interactions c... |
The relative contribution of personal and social information to explain individual and collective behavior in different species and contexts is an open question in animal ecology. In particular, there is a major lack of studies combining theoretical and empirical approaches to test the relative relevance of different h... |
During the Middle Ordovician, the salt deposits of the Majiagou Formation of the Ordos Basin in North China formed, the halite including various genetic types of fluid inclusion. In this study, fit-testing of primary inclusions was performed to reconstruct the physical and chemical conditions during original halite sed... |
This paper describes an improved technique of the restoration of an image degraded by a perfect low-pass imaging system and noise. The direct approach to such a problem using a simple extrapolation technique based on the sampling theorem does not give satisfactory results because of the extreme amplification of the noi... |
Neuroimaging studies examining the effects of aging and neuropsychiatric disorders on the cerebral cortex have largely been based on measures of cortical volume. Given that cortical volume is a product of thickness and surface area, it is plausible that measures of volume capture at least 2 distinct sets of genetic inf... |
Changes in the activity of enzymes involved in glutaminolysis and energy metabolism in the entire gastrointestinal (GI) tract of developing piglets are presented for the first time. The activities of glutaminase, glutamate dehydrogenase, oxoglutarate dehydrogenase, isocitrate dehydrogenase and alanine aminotransferase ... |
The enzyme argininosuccinate synthetase (ASS) initiates the metabolic pathway leading from L-citrulline to L-arginine, the only physiological substrate of all isoforms of nitric oxide synthases. The presence of ASS in glial cells in vivo was investigated by immunohistochemical methods in a model of rat brain inflammati... |
We initiate the study of distributed graph algorithms under the presence of Byzantine nodes. We consider the fundamental problem of testing the connectivity of a graph in the congested clique model in a Byzantine setting. We are given a n -vertex (arbitrary) graph G embedded in a n -node congested clique where an arbit... |
Objective: To simultaneously detect fetal aneuploidies and single gene diseases using a novel noninvasive prenatal testing (NIPT) method called the Targeted And Genome-wide simultaneous sequencing (TAGs-seq). Design: Comparison of TAGs-seq NIPT results with conventional NIPT and diagnostic results. Setting: Shenzhen Pe... |
Abstract The paper describes some functionality extensions for a D.C. motor speed control system with PID controller used as a didactic unit. The extensions are made in two directions: one at a physical-hardware level and the other one at software development of numerical algorithms and graphical interface. Both develo... |
We read with great interest the published paper by Gossec et al 1 which provided updated European League Against Rheumatism (EULAR) recommendations for pharmacological therapies for psoriatic arthritis (PsA). In this full-scale, evidence-based guideline, the authors proclaimed 6 overarching principles and 12 recommenda... |
First, for PsA with relevant skin involvement, the authors recommended methotrexate (MTX) as the standard treatment superior to other conventional synthetic disease-modifying antirheumatic drugs (csDMARDs). However, the evidence on the efficacy of MTX remains limited to date.2 Furthermore, the medication trends for pso... |
The Council for Medical and Health Research (MW-NWO) assessed the scientific quality of research proposals submitted to the Dutch Investigative Medicine Fund, and analysed if there had been changes over time in the proportion of proposals which the MW-NWO advised to reject, the role of reports of external reviewers and... |
The fast growing use of social networking sites among the teens have made them vulnerable to get exposed to bullying. Cyberbullying is the use of computers and mobiles for bullying activities. Comments containing abusive words effect psychology of teens and demoralizes them. In this paper we have devised methods to det... |
Ketanserin, which preferentially blocks 5-HT2-serotonergic receptors, was injected intravenously (i.v.) to patients with congestive heart failure in a bolus dose of 10 mg, followed by an i.v. infusion of 3 mg/h over a period of 4 h. The drug caused a decrease in total peripheral resistance and, conversely, an increase ... |
An Artificial Magnetic Conductor (AMC) is a type of metamaterial that can be used to enhance the performance in several antenna and microwave design applications. In this work we propose a novel geometry of AMC constructed of magnetically coupled helical elements that are smaller than those previously suggested and whi... |
SHORT COMMUNICATION Vismodegib, a Hedgehog (Hh) pathway inhibitor, was approved by the US Food and Drug Administration (FDA) in 2012 for the treatment of locally advanced (la) and metastatic (m) basal cell carcinoma (BCC). Interim results of the largest clinical study of vismodegib have shown complete (17.5%) or partia... |
There is little research about the effects of ultra-endurance exercise on arterial morphological and functional properties. The aim was to assess the acute changes of the carotid-femoral pulse wave velocity and carotid doppler-derived parameters following an ultra-marathon race as well as the intima-media thickness of ... |
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