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Corona Virus Infectious Disease (COVID-19) is an infectious disease. The COVID-19 disease came to earth in early 2019. It is expanding exponentially throughout the world and affected an enormous number of human beings starting from the last year. COVID-19 was declared “Pandemic” by the World Health Organization (WHO) o... |
We are making a comprehensive study of the ablation of elemental materials by femtosecond lasers. Specifically, we are examining the ablation of a wide range of metals, under vacuum and in ambient air, using 850-nm wavelength, 100-fs laser pulses in an intensity range approaching and extending beyond the air ionization... |
Paleoneurology, the study of the evolution of the brain, lies at the interface of neurology and paleontology. In its modern form, it was founded in Germany in the 1920s, the product of the unique educational background and inspiration of Ottilie (“Tilly”) Edinger (1897‐1967). Before Edinger’s work, the history of the v... |
McPherson correctly asserts that proponents and opponents of screening are fighting a misplaced propaganda battle,1 but the controversy will not be silenced by “dispassionate epidemiologists” agreeing on the best estimate for the effectiveness of breast screening. Even if this happened, the estimate (and associated out... |
Biflavonoids are pharmaceutically important compounds. Prenylation usually improves bioactivity; however, prenylated biflavonoids are rare in nature. Here, we report successful prenylation or geranylation of biflavonoids using fungal prenyltransferase CdpC3PT and its mutants. F253 was identified as a key residue relate... |
In this paper, we investigate the sum-rate maximization problem in a cooperative relay network, which employs non-orthogonal multiple access (NOMA). Specifically, we address the problem of optimal power allocation and relay precoder design. The corresponding optimization problem turns out to be non-convex. In order to ... |
Prediction of bridge component condition is fundamental for well-informed decisions regarding the maintenance, repair, and rehabilitation (MRR) of highway bridges. The National Bridge Inventory (NBI) condition rating is a major source of bridge condition data in the United States. In this study, a type of generalized l... |
[3H]Phencyclidine (PCP) binds to a single class of noninteracting binding sites in rat brain membranes with an affinity Kd of 0.25 microM and a maximal binding capacity BM of 2.4 pmol/mg of membrane protein. PCP derivatives also interact with the muscarinic and mu-opiate receptors in rat brain membranes with affinities... |
Femtosecond optical excitation of biased photoconductors has been demonstrated as an efficient optoelectronic technique of generating broadband far-infrared radiation in free space.' The limiting factor for the optical-toTHz conversion efficiency in these THz emitters is known to arise from the screening of the bias fi... |
PURPOSE |
Monte Carlo (MC) dose calculation is generally superior to analytical dose calculation (ADC) used in commercial TPS to model the dose distribution especially for heterogeneous sites, such as lung and head/neck patients. The purpose of this study was to provide a validated, fast, and open-source MC code, MCsquare, to as... |
METHODS |
First, MCsquare was validated using tissue-mimicking IROC lung phantom measurements as well as benchmarked with the general purpose Monte Carlo TOPAS for patient dose calculation. Then a comparative analysis between MCsquare and ADC was performed for a total of 50 patients with 10 patients per site (including liver, pe... |
RESULTS |
Comparison between MCsquare and TOPAS showed less than 1.8% difference for all of the dosimetric indices/TCP values and resulted in a 3D gamma index passing rate for voxels within the target in excess of 99%. When comparing ADC and MCsquare, the variances of all the indices were found to increase as the degree of tissu... |
CONCLUSIONS |
Given the differences found in the analysis, accurate dose calculation algorithms such as Monte Carlo simulations are needed for proton therapy, especially for disease sites with high heterogeneity, such as head-and-neck and lung. The establishment of MCsquare can facilitate patient plan reviews at any institution and ... |
The conventional OFDM-based pattern division multiple access (PDMA) systems suffer from the problem of slow side-lobe attenuation. To alleviate this problem, we propose a new modulation waveform design, namely the offset quadrature amplitude modulation based orthogonal frequency division multiplexing (OQAM-OFDM). The p... |
The purpose of the research is to use the ratio analysis to determine the level of efficiency of companies engaged in the production of textiles in the Republic of Serbia in the period from 2017 to 2019. The research was conducted on a sample of three companies engaged in the production of textiles, whose shares are li... |
Smartphones play a key role in several aspects of our daily life. Their range of application is constantly growing, making them versatile and necessary. However, mobile devices face an important problem: they hold an important autonomy requirement, which is constantly challenged by the short life of batteries. Research... |
Social constructivism has come of age in contemporary international relations (IR) theory. Indeed, more and more submissions to presses and journals in both Europe and America characterise themselves as constructivist or situate their arguments vis à vis those of constructivists. In substantive terms and as the three b... |
Present investigation describes the synthesis of a natural phenylalanine-rich cyclopolypeptide longicalycinin A (10) by coupling of dipeptide unit Boc-L-phe-L-tyr-OH with tripeptide unit L-pro-L-phe-gly-OMe followed by cyclization of linear segment. Synthesized cyclic pentapeptide was characterized by spectral techniqu... |
The main purpose of this paper is to define a new family of Szász–Mirakyan operators that depends on a non-negative parameter, say α. This new family of Szász–Mirakyan operators is crucial in that it includes both the existing Szász–Mirakyan operator and allows the construction of new operators for different values of ... |
During the past few years, changes in medical practice and curricula have heightened the need to establish guidelines for expected competencies in community pediatrics. The shift of the Accreditation Council for Graduate Medical Education (ACGME) toward an outcome-focused process for the training of physicians and the ... |
Specifically, the 1996 (as well as the revised 2003) RRC requirements called for structured educational experiences that would prepare residents to advocate on behalf of the health of children within communities. It was recommended that curricula should include but not be limited to community-oriented care with a focus... |
A competency can be defined as an ability, a proficiency, or an entire skill set that evolves over time and involves performance of behaviors based on a complex set of knowledge, skills, and attitudes.2 Translating knowledge into patient care; communicating with patients, family members, and other health care professio... |
Address correspondence to Lynn C. Garfunkel, MD, Rochester General Hospital, 1425 Portland Ave, Rochester, NY 14621. E-mail: lynn.garfunkel{at}viahealth.orgBase Station Application Optimizer |
Expectation and requirements for future wireless communication systems continue to grow and evolve. Long-Term Evolution (LTE) is a recent effort taken by cellular providers and equipment vendors to step into wireless broadband market. The key enhancements target an introduction of new all-IP architecture, enhanced link... |
Background and purpose: MuSK‐positive myasthenia gravis (MG) is diagnosed in 0–48% of cases with generalized seronegative MG in different populations. The presence of anti‐MuSK antibodies generally relates to a severe course and lack of response to thymectomy. We analyzed for the first time the serology and clinical c... |
Strategic Management of Security Information through an Entropy-Based Alert Correlator We present an integrated sy stem to process in real time a hug e incoming stream of alerts produced by current intrusion detection sy stems. A key component of this sy stem includes an unsuper vised clustering algorithm that combines... |
All‐inorganic perovskite CsPbBr3 has drawn a lot of interest as an active layer applied in photovoltaics due to its outstanding stability in ambient air. However, the procedure of preparing high‐quality CsPbBr3 films still remains a serious challenge because of the tedious process and toxic solvent. Herein, a solvent e... |
An infant presented at birth with a cutaneous lesion that developed the characteristics of purpura fulminans. He sustained a cerebral infarction during the first 4 days of life, which was initially misinterpreted to be cerebral hemorrhage resulting from thrombocytopenia and hypofibrinogenemia. After the diagnosis of Pr... |
As technologies are expanding, the demand for power supply also increases. This causes the demand for power is difficult to be fulfilled as non-renewable sources are reducing. Therefore, the microgrid concept is introduced, where it is constructed with renewable energy sources, energy storage devices and loads. There a... |
Approximately eight billion therapeutic injections are administered outside of medical treatment facilities annually. The management of diabetes mellitus (DM) includes self-monitoring of blood glucose levels and administration of insulin and injectable non–insulin-related medications. The lancets, needles, and syringes... |
To test the hypothesis that concentration polarization of atherogenic lipids may occur in the arterial system and play an important role in localization of atherosclerosis, we simulated and measured in vitro the luminal surface concentration of low density lipoprotein (LDL) in local stenosis at the distal end of caroti... |
Purpose: Small bowel adenocarcinoma is a rare cancer and usually occurs in elderly males. A 12-year-old girl with metastatic small bowel adenocarcinoma and her clinical course are described. The difficulties in making the pathologic diagnosis and the literature arc also reviewed. Patients and Methods: A 12-year-old gir... |
Anastomotic leakage (AL) is one of the most feared postoperative complications after anterior resection (AR) of rectal cancer. An adequate blood supply at the anastomotic site is regarded as a prerequisite for healing. We hypothesize that the Aortic Calcification Index (ACI) might reflect the severity of atherosclerosi... |
were in the streets; meanwhile globalization was treated as an inevitability. Martin, of course, is not the first to explore consumer ideology in the media, but he is the first to give its magical ability to undercut working-class issues and aspirations serious book-length attention. Our understanding is deepened by hi... |
ABSTRACT The global demand for technically educated persons is greater than the supply. It is believed that interest and school experience can influence career choice. 624 Slovenian high school students participated in the survey. Exploratory and Confirmatory Factorial Analysis procedures were used to investigate the i... |
Treatments for convulsive status epilepticus (SE) have a wide range of effectiveness. The estimated effectiveness of non‐intravenous benzodiazepines (non‐IV BZDs) ranges from approximately 70% to 90% and the estimated effectiveness of non‐benzodiazepine antiseizure medications (non‐BZD ASMs) ranges from approximately 5... |
In this paper, we propose a tree search approach to generate and evaluate cooprative behavior online in multiagent systems. It was difficult to apply a tree search methodology to tasks that the state-action space is continuous and requires realtimeness. However, it has become possible to apply such an approach since th... |
&NA; For most multigenic disorders, clinical manifestation (penetrance) and presentation (expressivity) are likely to be an outcome of genetic interaction between multiple susceptibility genes. Here, using gene knockouts in mice, we evaluated genetic interaction between loss of Ret and loss of Sema3d, two Hirschsprung ... |
Hydrogen peroxide (H(2)O(2)) stimulates the release of arachidonic acid from cells, but the signaling mechanism(s) involved remains to be elucidated. We investigated the roles of alpha-type cytosolic phospholipase A(2) (cPLA(2)alpha), Src family kinases (Src) and protein kinase C (PKC) in the release of arachidonic aci... |
Anyone who has been near an emergency department (ED) in the US since the middle of March 2020 knows that the census decreased precipitously as the coronavirus disease 2019 (COVID-19) pandemic intensified. Pundits in the medical and mass media have speculated on where ED patients, especially those with ST-segment eleva... |
An overmoded photonic crystal waveguide based on the three-dimensional woodpile lattice has been proposed for a highenergy charged particle accelerator. Critical to overall accelerator efficiency is the ability to couple power into an uninterrupted vacuum waveguide in a very small volume. We present designs and simulat... |
OBJECTIVE |
To observe the effects of low-level laser irradiation on mesenteric microcirculation of rats in vivo in the early stage of endotoxemia (ETM). |
METHODS |
The experimental model of ETM was reproduced by injection of lipopolysaccharide (LPS). Sixty healthy male Sprague-Dawley (SD) rats were divided into three groups used random number table: control group, LPS group and low-level laser irradiation group, each group included 20 rats which were subdivided into four temporal... |
RESULTS |
The blood flow velocity (mm/s) of the mesenteric microcirculation in LPS group was accelerated at 1 hour and 2 hours after LPS injection (1 hour: 0.190+/-0.007 vs. 0.174+/-0.009, 2 hours: 0.200+/-0.010 vs. 0.172+/-0.015, both P<0.05, respectively), but decelerated at 6 hours (0.116+/-0.015 vs. 0.164+/-0.011, P<0.05). T... |
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