text stringlengths 0 10.1k |
|---|
The main question of the future: will we live or die? It hides behind all the other questions about: how quickly global warmingwill occur, whether nuclear war is possible, what are the successes of human genome editing projects, and what will person of the futurebe like? How different will be the generations of the 21s... |
This paper describes how modern methods on robust controller design can be applied to a simple laboratory experiment which may be used for education in an advanced course on control systems design. The pendulum dynamics are made "uncertain" by dividing the motor shaft into two parts and by combining these parts with a ... |
Organic semiconductor distributed feedback (DFB) lasers are of interest as external or chip-integrated excitation sources in the visible spectral range for miniaturized Raman-on-chip biomolecular detection systems. However, the inherently limited excitation power of such lasers as well as oftentimes low analyte concent... |
The article analyzes trends in innovative development at the national, regional and municipal levels of the Russian economy. The situation of innovation stagnation in the country is revealed, which occurred despite the active innovation policy pursued by the Federal government. As a result of the study of statistical i... |
U.S. troops withdrew from the forward operating location (FOL) in Manta, Ecuador, in 2009 after a decade of presence. The withdrawal was celebrated not only by Ecuadorian activists, who had protested the FOL since it was established in 1999, but also by anti-U.S. military base movements around the world, which became c... |
We report a rare case of infected left atrial myxoma. A 69-year-old male was admitted to our hospital due to cerebral infarction accompanied by lower limb ischemia. Transesophageal echocardiography showed a mobile left atrial tumor. On the 16th hospital day, he sufferd from high fever and Klebsiella pneumoniae was posi... |
ABSTRACT 1. Myoblast proliferation and differentiation is one of the most important biological processes in the development of skeletal muscle. MicroRNAs (miRNAs) play a crucial role in this process. 2. In this study, the expression level of miR-181a-5p was detected, which found that miR-181a-5p was expressed different... |
Wearable apps are becoming increasingly popular in recent years. However, to date, very few studies examined the issues that wearable apps face. Prior studies showed that user reviews contain a plethora of insights that can be used to understand quality issues and help developers build better quality mobile apps. There... |
The purpose of the research is to diagnose the extent to which the respondents in the field are aware of the importance of applying social responsibility, as well as the extent to which there are significant differences in the employees' understanding of the importance of applying the principles and the relationship be... |
- The results of the research showed that respondents in the field are aware of the importance of applying the principles of social responsibility. The results showed high levels of awareness of all principles. |
- There is a significant difference in the perception of the field workers concerned about the importance of applying social responsibility due to some demographic variables (experience, educational level) |
- The study showed a statistically significant relationship with the application of social responsibility due to the demographic variables (experience, educational level, job level). |
- Based on the results of the research, a number of recommendations and suggestions were presented, including the need to continue to support the senior management and its commitment to the implementation of social responsibility, in addition to embedding these principles in their organizational culture.Health status a... |
The issue of biased selection has taken on increased importance because of the growing numbers of Medicare beneficiaries enrolled in capitated systems. One way to deal with biased selection is through adjusting payment to health plans to reflect enrollee health status. This paper reviews proposed health status adjustor... |
Higher plants play a key role in Bioregenerative Life-Support Systems (BLSS) for long-term missions in space, by regenerating air through photosynthetic CO2 absorption and O2 emission, recovering water through transpiration and recycling waste products through mineral nutrition. In addition, plants could provide fresh ... |
The search engine Shodan crawls the Internet to collect banners from Internet connected devices. When making this information publicly available, anyone can search and find these devices. Results from Shodan show that it is not only web or mail servers that are connected, but also industrial Control Systems (ICS) and I... |
The legal issue regarding the drugs imported in our country is briefly discussed in this review. Being a densely populated country, India has a wide scope in pharmaceutical industry for foreign countries to sell their drugs in Indian market. In India, the regulatory process of import of drugs is very complicated and it... |
OBJECTIVE |
To assess the efficacy of the purine analogue fludarabine monophosphate (FAMP) as salvage therapy in patients at Groote Schuur Hospital with chronic lymphocytic leukaemia (CLL) refractory to standard therapy. |
DESIGN |
Non-randomised trial. |
SETTING |
Tertiary care, referral academic hospital. |
PATIENTS |
Seven patients with B-lineage CLL, 4 in Rai stage IV and 1 each in stages A(I), A(II) and A(III), refractory to treatment with chlorambucil or cyclophosphamide, with or without whole-body irradiation. |
INTERVENTION |
Intravenous FAMP at a dose of 25 mg/m2 daily for 5 days every 28 days. |
MAIN OUTCOME MEASURES |
Partial remission, complete remission, stable disease or progressive disease. |
RESULTS |
Two patients entered CR and 4 PR after a median of 8 courses of treatment (range 2 - 12). One patient died of Pneumocystis carinii pneumonia after 3 courses of therapy. The most common adverse effect of the treatment was myelosuppression, with the nadir of neutrophil counts being less than 0.5 x 10(9)/1 in 5 patients. ... |
CONCLUSION |
FAMP is effective as a cytoreductive agent in patients with CLL refractory to alkylating agents, with or without whole-body irradiation.DDS-PLL Phase Shifter Architectures for Phased Arrays: Theory and Techniques |
The main purpose of this paper is to review the framework behind direct digital synthesizer phase-locked loops (DDS-PLLs), as well as to provide a set of novel techniques that can be used during the development and the deployment of phased arrays based on local oscillator (LO) phase shifting approaches. A beam steering... |
Most of us hold opinions on contemporary issues in work practice, in all its broad dimensions. Sounding Board is a regular feature of this publication, designed to provide a forum for expressing such views, whether mainstream or controversial.The opinions expressed in this section may not necessarily represent the view... |
There is ample evidence that vitamin D deficiency rickets in man is associated with hyperaminoaciduria (1). Further studies (2) on renal clearance have de monstrated that elevated urinary amino acid excretion results from diminished reabsorption of it by the renal tubular cells. Many attempts (3, 4), however, failed to... |
When Prehistoric Man created the first domestic fires he probably caused the earliest form of air pollution, as is evidenced by reported findings of soot on the ceilings of his caves. However, it is generally acknowledged that the birth of environmental pollution as we know it came with the Industrial Revolution (1750-... |
An improved super-resolution image reconstruction algorithm based on dictionary-learning is studied for the time-consuming algorithms in the existing dictionary training process. In this paper, the reconstruction of image super resolution is realized from the compressed sensing theory. The image patches are conveyed by... |
Soft lithography and thermal evaporation of gold were used to create microfluidic channels with metal only on the bottom surface of each channel, in a process similar to nanotransfer printing (nTP). Micron-scale patterns of the bioelectronic material purple membrane (PM) were fabricated by combining standard soft litho... |
This article takes the large-scale doubly-fed wind farm into the power system as the background, considers the Crowbar circuit input and converter control strategy, and comprehensively considers the different voltage drop depths, slip rates, Crowbar resistance, and active power indicators of the doubly-fed wind turbine... |
The authors address the problem of editing signals such as 2D colour images or 3D coloured meshes that are represented under the general framework of graph signals. As state-of-the-art editing approaches decompose an image into several layers in order to manipulate them, they propose a hierarchical multi-layer decompos... |
Purpose of reviewTo review the data that contribute to the debate on the optimal time to initiate highly active antiretroviral therapy in HIV-infected individuals, with a focus on the information that is available from cohort studies. Recent findingsThe findings from cohort studies generally support initiation of highl... |
Recall that nitrogen has five valence electrons and therefore requires three electrons or bonds to complete its octet (see Amine Tutorial). Based on this valence and bonding order, nitrogen forms three bonds in its neutral state and maintains one pair of non-bonded electrons (NBEs). In amides one of the three bonds is ... |
Over the past few decades, we have seen a tremendous progress in the development of implantable ventricular assist devices (VAD). However, these devices are mainly developed for adult patients. For the patients under age 5 who have chronic heart failures, physicians must resort to extracorporeal circulatory support dev... |
Trace analysis of oil-in-water (O/W) has wide applications in life science, industry and environmental monitoring (such as oil spilling). In this paper, with the aid of surfactant, diesel was dispersed in water as O/W emulsion, which can be detected by using visible LED and metal-waveguide-capillary (MWC). Due to the e... |
Relations between children's sleep and cognitive functioning were examined over 2 years, and race and socioeconomic status were assessed as moderators of effects. Third-grade African American and European American children (N = 166; M = 8.72 years) participated at Time 1 and again 2 years later (N = 132). At both Time ... |
Once the post–World War II division of Europe had entrenched itself, the enormous risks of challenging the status quo through military force meant that all parties sought alternative ways of contesting the Cold War. Two new books shed light on the kinds of alternative strategies used by the West to undermine East Germa... |
To the Editor: Arterial tortuosity syndrome (ATS; OMIM 208050) is a rare connective tissue disorder characterized by elongation and tortuosity of the greater and systemic arteries (1–13). Affected individuals often display aneurysms, dilatation, stenosis, ventricular hypertrophy, elevated blood pressures, and pulmonary... |
Recent deep Re-ID models mainly focus on learning high-level semantic features, while failing to explicitly explore color information which is one of the most important cues for person Re-ID. In this paper, we propose a novel Color-Sensitive Re-ID to take full advantage of color information. On one hand, we train our m... |
Combining photoelectron spectroscopy with tunable laser pulse excitation allows us to characterize the Coulomb barrier potential of multiply negatively charged silver clusters. The spectra of mass- and charge-selected polyanionic systems, with z=2-5 excess electrons, show a characteristic dependence on the excitation e... |
Mineralocorticoid receptor antagonists (MRAs) improve outcomes in heart failure with reduced ejection fraction (HFrEF), but are underutilized. Hyperkalaemia may be one reason, but the underlying reasons for underuse are unknown. The aim of this study was to investigate the independent predictors of MRA underuse in a la... |
The purpose of this study was to explore changes in body sensation through muscular relaxation by means of measurement of tactile two-point limen. This study comprised two experiments. The first experiment, in which twenty female college students participated, was carried out to examine the effect of relaxation on two-... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.