text stringlengths 0 10.1k |
|---|
IGAP flap closure for perineal defects, does offer the advantage of compatibility with both minimally invasive and open procedures and the avoidance of using irradiated tissue. This case series does demonstrate the feasibility of IGAP flaps as viable option to cover perineal defects following radical low rectal cancer... |
High-throughput imaging surface plasmon resonance biosensing based on ultrafast two-point spectral-dip tracking scheme. |
Wavelength interrogation surface plasmon resonance imaging (λSPRi) has potential in detecting 2-dimensional (2D) sensor array sites, but the resonance wavelength imaging rate limits the application of detecting biomolecular binding process in real time. In this paper, we have successfully demonstrated an ultrafast λSPR... |
Web application penetration testing is composed of numerous skills which require " hands on " practice to learn. To prepare for certification exams, master concepts learned in training, and practice pen testing, a deliberately vulnerable web application is needed. While several excellent applications exist, very few pr... |
Adolf Zsigmondy and his son Ottó Zsigmondy were dentists of Hungarian origin who lived in Vienna. It was A. Zsigmondy's idea the method of teeth marking on the Zsigmondy-cross called later after him. This is the basis of the presently used marking method recommended by the FDI. He was the first to describe the contact ... |
People’s inclination toward medical textiles for healthy life style has created a rapidly increasing market for antimicrobial textiles, which, in turn, has stimulated intensive research and development. The aim of our study was to prepare cellulose fabrics finished by allicin-conjugated nanocellulose, whose properties ... |
ed by H. B. M. Murphy MIGRATION, ETHNICITY AND DIAGNOSIS by R. LITTLEWOOD and M. LIPSEDGE. Typescript, 11 pp. This paper examines the question of whether high rates of mental illness among certain ethnic minorities are real or are due to diagnostic bias and failure to distinguish culturally determined beliefsOur Heroic... |
Utilizing Joseph Campbell's concept of the hero's adventure, this article provides a technique through which clients can story their lives and challenges as an unfolding personal myth or epic adventure. The use of personal narrative and storytelling has found efficacy in the counseling field and, as such, forms a usefu... |
We present a method to determine the concentration of nucleic acids in a sample by partitioning it into droplets with a nonuniform volume distribution. This digital PCR method requires no special equipment for partitioning, unlike other methods that require nearly identical volumes. Droplets are generated by vortexing ... |
Effect of degraded lambda-carrageenan, which induces colitis in rodents, on the development of beta-catenin-accumulated crypts (BCAC) being putative precancer lesions of colon cancer was investigated in male DBA/2J mice initiated with azoxymethane (AOM). In a preliminary experiment, male DBA/2J mice among seven differe... |
This attenuator comprises a pair of axially aligned anti-parallel Brewster angle windows that are rigidly secured in a cylindrical adjustment tube that is rotatably secured in a mounting tube. The attenuation of a linearly polarized laser beam that is incident along the axis of the attenuator is continuously varied fro... |
The K x‐ray emission spectra from the cations in KCl, CaF2, CaO, CaC2, CaCO3, and CaSO4(2H2O) are discussed. The energy separations between the outer cation and anion electronic shells are derived from the spectra. In the cases of the simple ions these energy separations can be calculated using a point ion model. The i... |
Coatings have a tremendous impact on economy as they reduce corrosion that has an estimated cost of 3% of the world's GDP. Hydrophobic coatings are particularly efficient for this purpose and the challenge is to produce cost effective and environmentally friendly, highly hydrophobic, cohesive and non-porous coatings ap... |
Tumorigenesis driven by abnormal DNA methylation has highlighted the need to develop a portable, rapid and sensitive strategy for accurate methylation detection with a specific cancer-prognostic gene, which caters to the popularization of precision medicine. In this study, a site-specific biosensor for both visual and ... |
No studies have been published concerning the comparison between gingival and papillary recession in the maxillary esthetic zone (including incisors, canines, and premolars) regarding age and sex. This study addressed this issue. Adults (n = 250) with fully erupted permanent dentitions, healthy gingivae, and natural te... |
The primary work of defect detection of Digital Radiography(DR) image is the segmentation and measurement of defect regions.The precision of defect measurement,to a large extent,depends on the accuracy of segmentation.Based on the curve evolution theory and level set method for segmentation,C-V model has taken regional... |
The clinical characteristics and coronary angiographic findings in 50 patients with spontaneous angina (SA) were studied. Coronary angiography did not disclose any severe fixed narrowing in 7 patients with SA only; the episodes of SA in these patients is the result of subtotal occlusion of a major coronary artery induc... |
The conventional wisdom on China's domestic political situation is one of tension and turmoil. China's leaders seem beset with a host of problems for which they have no ready answer. They face a growing number of popular protests in the cities and the countryside. Corruption seems to be endemic, and the Chinese Communi... |
We study the relative efficiencies of the random and systematic approaches to automated software testing. Using a simple but realistic set of assumptions, we propose a general model for software testing and define sampling strategies for random (R) and systematic (S0) testing, where each sampling is associated with a s... |
Abstract Community-based watershed management is different from the traditional natural resources management. Traditional natural resources management is a way from up to bottom, but the community-based watershed management is from bottom to up. This approach focused on the joining of different stakeholders in integrat... |
The basic virtual memory-mapped communication (VMMC) model provides protected, direct communication between the sender's and receiver's virtual address spaces, but it does not support high-level connection-oriented communication APIs well. This paper presents VMMC-2, an extension to the basic VMMC. We describe the desi... |
The objectives of this study were to 1) determine the distribution and severity of anemia in Vietnam and 2) assess potential risk factors for anemia. 9550 households in 53 provinces were covered using a stratified two‐stage cluster survey. Selected household members were interviewed; intestinal helminthes were tested b... |
Cardiovascular implantable electronic devices (CIED) are implanted increasingly frequently. CIEDs are indicated for the treatment of bradycardia, tachycardia and heart failure and therefore improve quality of life and life expectancy. CIED can treat ventricular arrhythmias that would be fatal without immediate care. Ho... |
Abiotic factors severely affect, alter and limit the yield and quality of the plants. Among them, a significant stress to plant growth and quality is given by cold or low temperature. In order to minimize or localize the cold stress, plants adopt mechanisms in the form of elevated expression levels of cold responsive g... |
Maximum sensory conduction velocity, duration and amplitude of the sensory evoked potentials at the wrist on stimulating digits 1, 2, 3 and 5, were determined bilaterally in 21 left-handed subjects with an age range from 6 to 47 years. The amplitude of the sensory evoked potential at the wrist was larger in the right h... |
Objective: To understand the developmental characteristics of early ocular biological parameters in patients with congenital cataract. Methods: Retrospective case series study. The ocular biometry data such as the axial length, corneal curvature, anterior chamber depth and central corneal thickness of 169 patients unde... |
BACKGROUND |
Sleep apnea is an important comorbidity in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Although the increased prevalence of sleep apnea in patients with ESRD is well established, few studies have investigated the prevalence of sleep apnea in patients with nondialysis-dependent kidney ... |
METHODS |
Two hundred fifty-four patients were recruited from outpatient nephrology clinics and hemodialysis units. All patients completed an overnight cardiopulmonary monitoring test to determine the prevalence of sleep apnea (respiratory disturbance index ≥ 15) and nocturnal hypoxia (oxygen saturation < 90% for ≥ 12% of monito... |
RESULTS |
The prevalence of sleep apnea increased as eGFR declined (eGFR ≥ 60 mL/min/1.73 m(2), 27%; CKD, 41%; ESRD, 57%; P = .002). The prevalence of nocturnal hypoxia was higher in patients with CKD and ESRD (eGFR ≥ 60 mL/min/1.73 m(2), 16%; CKD, 47%; ESRD, 48%; P < .001). |
CONCLUSIONS |
Sleep apnea is common in patients with CKD and increases as kidney function declines. Almost 50% of patients with CKD and ESRD experience nocturnal hypoxia, which may contribute to loss of kidney function and increased cardiovascular risk.Location of the stapedius muscle with reference to the facial nerve in patients w... |
Abstract Background: Detailed investigations of the stapedial muscle (SM) in congenital aural atresia (CAA) patients have yet to be adequately conducted. Objectives: To assess image variations in the mastoid segment of the facial nerve (FN) and SM in CAA. Materials and methods: A total of nine patients comprising of 9 ... |
MOTIVATION |
mRNA sequences and expressed sequence tags represent some of the most abundant experimental data for identifying genes and alternatively spliced products in metazoans. These transcript sequences are frequently studied by aligning them to a genomic sequence template. For existing programs, error-prone, polymorphic and c... |
RESULTS |
We took a novel approach to spliced alignment that meaningfully combined information from sequence similarity with that obtained from PSSM splice site models. Scoring systems were chosen to maximize their power of discrimination, and dynamic programming (DP) was employed to guarantee optimal solutions would be found. T... |
AVAILABILITY |
The source code, binaries, scripts, scoring matrices and splice site models for human, mouse, rice and Caenorhabditis elegans utilized in this study are posted at http://blast.wustl.edu/exalin. The software (scripts, source code and binaries) is copyrighted but free for all to use.Clinical Immunogenicity Risk Assessmen... |
This article provides a theoretical case-study risk assessment report for a low-risk monoclonal antibody (mAb) therapeutic. In terms of risk, there are considerations around risks to safety, but also risks regarding effects on pharmacokinetics (PK), pharmacodynamics (PD), and efficacy. Much of the discussion in this do... |
This report describes a laboratory exercise that was incorporated into a Cell Biology and Molecular Biology advanced course. The exercise was made for a class size with eight students and was designed to reinforce the understanding of basic molecular biology techniques. Students used the techniques of reverse transcrip... |
The 57-year-old man was underwent sigmoid colostomy due to unresectable rectal carcinoma. Then he was treated with chemotherapy of levofolinate/5-fluorouracil/oxaliplatin(FOLFOX). After completion of 12 courses of chemotherapy, MR revealed responses. The patient underwent a low anterior resection. Preoperative chemothe... |
The present study investigated the joint impact of co-occupants and codefendants criminal behavior on adolescent criminal behavior using official Dutch police records. Co-occupant and co-defendant criminal behavior were used as proxies for family and peer criminal behavior, respectively. Data spanning 8 years (2010–201... |
Twenty‐eight patients with locally advanced, unresectable non‐small cell lung cancer (NSCLC) received neoadjuvant chemotherapy with cisplatin (120 mg/m2 on days 1 and 29) and vinblastine (4 mg/m2 weekly for 6 weeks). At the completion of induction chemotherapy, all patients were assessed for resectability. Those patien... |
Health and environmental impacts of graphene-based materials need to be thoroughly evaluated before their potential applications. Graphene has strong cytotoxicity toward bacteria. To better understand its antimicrobial mechanism, we compared the antibacterial activity of four types of graphene-based materials (graphite... |
What is the central question of this study? We examined whether the macrophage‐synthesized antioxidant 7,8‐dihydroneopterin was elevated in Duchenne muscular dystrophy (DMD) patients. We then examined whether 7,8‐dihydroneopterin could protect dystrophic skeletal mouse muscle from eccentric contraction‐induced force lo... |
In 1987, Makimoto's wave described the semiconductor industry's cyclical alternation between standardization and customization, providing insight about chip innovation's great impact on the computer revolution. The wave's originator reviews its past and current predictive abilities, offering a glimpse of where computin... |
The aims of liberalism—which is often confused with value pluralism—are routinely challenged by persons whose primary commitments lie elsewhere. In his weighing the pros and cons of liberal democratic states versus an Islamic state, Ahmad Yousif has offered an impressive challenge to liberals, but in doing so has confu... |
Outcrossing provides better survival than self-fertilization during coevolution between a host and its parasite. Most organisms reproduce through outcrossing, even though it comes with substantial costs. The Red Queen hypothesis proposes that selection from coevolving pathogens facilitates the persistence of outcrossin... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.