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This paper aims at an extended understanding of the design facilitators' role, here implementation mediators, in participatory design practices. In reflecting connectedness between use and design in a distributed open source software design practice, a particular focus is devoted to the implementation mediator's intera...
Modal items of different semantic types can only be combined in a specific order. Epistemic items, for instance, cannot be embedded under deontic ones. I’ll argue that this fact cannot be explained by the current semantic theories of modality. A solution to this problem will be developed in an update semantics framewor...
Salivary duct carcinoma (SDC) is a distinct but rarely reported clinicopathological entity arising in the ductal epithelium of the salivary glands. This high-grade malignancy shares similar histopathological features with infiltrating duct carcinoma of the breast. SDC was established as a distinct clinicopathological e...
1H double quantum (DQ)/1H single quantum (SQ) correlation solid-state NMR spectroscopy is widely used to obtain internuclear 1H-1H proximities, especially at fast magic-angle spinning (MAS) rate (>60 kHz). However, to date, 1H signals are not well-resolved because of intense 1H-1H homonuclear dipolar interactions even ...
Failure to suppress thrombin generation during cardiac surgery promotes fibrin generation, fibrinolysis, and a consumptive coagulopathy. Acquired deficiencies of antithrombin III may play a contributory role. We hypothesized that antithrombin III supplementation to normal physiologic concentrations would decrease throm...
The current article examines the assumptions of the MZ co-twin control method that has been applied in attempts to gain more accurate estimates of the returns to education by naturally ‘controlling’ for individual differences on which MZ twins are matched. The current study examined 1738 MZ and 926 DZ twins from Minnes...
BACKGROUND
Gastric cancer (GC) is one of the most common and devastating tumor conditions. Its development is closely linked to an infection with Helicobacter pylori and chronic, cytokine-driven inflammation. The proinflammatory cytokine Interleukin-33 (IL-33), its membrane bound cellular receptor ST2L and its soluble receptor sS...
METHODS
Thirty patients with adenocarcinoma of the stomach or the esophagogastric junction were prospectively enrolled in the current study. 51 patients with Helicobacter pylori positive or negative gastritis and 40 healthy volunteers served as control group. Levels of IL-33 and sST2 were determined by ELISA and their relation...
RESULTS
Soluble ST2 levels in GC were significantly higher than in gastritis or healthy controls (p< 0.0001). Furthermore, higher levels of sST2 were seen in patients with lower degree of tumor differentiation. Soluble ST2 was significantly associated with a more advanced tumor stage (p= 0.018), metastatic disease (p= 0.014) a...
CONCLUSION
Soluble ST2 is associated with advanced and metastatic disease in GC patients and significantly correlates with the duration of the disease. The IL-33/sST2 ratio may offer a new, interesting approach in identifying GC patients.Current velocity as a factor in determining macroinvertebrate assemblages on wood surfaces
The velocity of moving water near submerged wood surfaces may be an important factor for shaping benthic communities in sandy-bottomed streams. As wood can be suspended above the streambed and be kept free of inundating sediments, wood substrates may provide the primary hard surface for macroinvertebrate colonization. ...
BACKGROUND
Ruptured liver after transplant is a rare complication. It can lead to graft or patient loss. Few reports are available in literature.
CASE REPORT
A 58 y old male patient underwent a deceased donor liver transplant due to hepatitis B virus related cirrhosis. The donor was a 38 y old trauma victim. There were no obvious injuries involving the liver during organ recovery but multiple petechiae appeared on the surface of the right lobe after preservative solution in...
CONCLUSIONS
Hematomas secondary to interventional procedures may be treated conservatively but spontaneous hematomas mostly will need surgery. The presence of petechiae on the surface of the graft may indicate a high energy injury and the possibility of intrahepatic hematoma that may rupture after implantation.Improvement of renew...
Grey theory is one of the new mathematical theories born out of the concept of the grey set. It is an effective method used to solve uncertainty problems with discrete data and incomplete information. In this paper, an improved grey GM (1, 1) model, using a technique that combines residual modification with the Markov ...
 
Key words: Renewable energy, Grey model, Markov model.Genicular Artery Embolization for Primary Knee Osteoarthritis.
Genicular artery embolization (GAE) is a novel treatment for knee osteoarthritis (OA) with increasing interest and utilization worldwide. The genicular arteries are selectively embolized using microspheres with subsequent cessation of abnormal synovial hyperemia, a process believed to arrest the inflammatory changes an...
CONTEXT
Prior research suggests that drug abuse (DA) is strongly influenced by both genetic and familial environmental factors. No large-scale adoption study has previously attempted to verify and integrate these findings.
OBJECTIVE
To determine how genetic and environmental factors contribute to the risk for DA.
DESIGN
Follow-up in 9 public databases (1961-2009) of adopted children and their biological and adoptive relatives.
SETTING
Sweden.
PARTICIPANTS
The study included 18 115 adopted children born between 1950 and 1993; 78,079 biological parents and siblings; and 51,208 adoptive parents and siblings.
MAIN OUTCOME MEASURES
Drug abuse recorded in medical, legal, or pharmacy registry records.
RESULTS
Risk for DA was significantly elevated in the adopted offspring of biological parents with DA (odds ratio, 2.09; 95% CI, 1.66-2.62), in biological full and half siblings of adopted children with DA (odds ratio, 1.84; 95% CI, 1.28-2.64; and odds ratio, 1.41; 95% CI, 1.19-1.67, respectively), and in adoptive siblings of ...
CONCLUSIONS
Drug abuse is an etiologically complex syndrome strongly influenced by a diverse set of genetic risk factors reflecting a specific liability to DA, by a vulnerability to other externalizing disorders, and by a range of environmental factors reflecting marital instability, as well as psychopathology and criminal behavio...
Philosophers’ intuitions about what constitutes autonomy are largely driven by the exemplars or paradigms that we recognize. There are indefinitely many exemplars, inasmuch as there are relatively private personae that serve as autonomy exemplars such as our parents, third grade teacher, or, for the megalomaniac, onese...
The Conners’ Rating Scales are one of the most used instruments for attention deficit/hyperactivity disorder (ADHD). Nonetheless, in the latest edition, the Inattention scale was not statistically supported. This study examined the dimensionality of the Italian version of the Conners 3–Self-Report scale testing both a ...
This report brings together the exploration and the main findings of the case-based learnings in the perspective of the food system approach and transition pathwaysfor Uganda.As part of the project Feeding Cities and migration settlements-dedicated to gain a better understanding to create sustainable, resilient urban f...
During the recent decade an increasing number of inquiries concerning cases of overdoses exhibiting typical signs of the serotonin syndrome have been recorded at the Swedish Poisons Information Centre. Four of these cases are presented together with a review of the literature. All patients had overdosed moclobemide and...
As ever larger mode area fibers are designed and incorporated into high-power amplifiers, bend-induced mode distortion becomes an important limitation. In any reasonable coiled-fiber arrangement, bend distortion can reduce mode area, gain interaction, and suppression of higher-order modes. These impacts are reviewed, a...
Drop-weight impact tests are used routinely to characterize the handling safety of explosives. Numerous studies have sought to connect various physical and chemical properties of the energetic molecules and materials to their measured impact sensitivities. Wenograd in the early 1960s demonstrated that there is a strong...
(ProQuest: ... denotes non-US-ASCII text omitted.)Leaders of the Anglo-Saxon Church: From Bede to Stigand . Edited by Alexander R. Rumble . Publications of the Manchester Centre for Anglo-Saxon Studies, 12. Woodbridge, U.K. : Boydell , 2012. xii + 204 pp. $95.00 cloth.Book Reviews and NotesThis volume is a collection o...
AIM
To evaluate the effectiveness of antihypertensives in reducing neurocognitive outcomes in elderly patients.
PATIENTS & METHODS
We conducted a systematic literature search of randomized trials in which hypertensive patients with a mean age ≥65 years received antihypertensive or control treatment. Outcomes were stroke, transient ischemic attack, cognitive decline and dementia. We included 14 trials for meta-analysis.