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Contrary to the existing theories of private label products, we demonstrate that the introduction of a private label product by a retailer may improve the profits of the supplier of a competing national brand product. Our theory is built on two main elements. First, the introduction of a private label product may expan...
Introduction The Family Healthcare Strategy (FHCS), the new model of Primary Care adopted by the Brazilian Ministry of Health, with its territoriality and regular visits by community health workers, provides an excellent network for treating depressed elderly. We aimed to estimate the prevalence of depression among old...
We prospectively studied pregnancy outcome in 428 women with gestational diabetes mellitus (DM) and 196 women with pregestational DM, with particular reference to the influence of maternal obesity and excessive weight gain. These were consecutive singleton pregnancies delivered in our institution over 5 years. After co...
Broadcast authentication plays an important role in wireless sensor networks. In this paper, we propose key predistribution based broadcast authentication scheme. In the scheme the base station can derive all keys used for broadcast authentication from initial parameters and sensor nodes are just able to deduce keys ex...
Background: Patient-reported outcome measures are an important metric in evaluating treatment efficacy of reconstructive surgery. Toe-to-hand transfer can restore vital prehensile function; however, this surgery is complex, extensive rehabilitation is required, and there are concerns about donor-site morbidity. This st...
Department of Critical Care Medicine, The First Affiliated Hospital of Shandong First Medical University, Jinan, China; Medical Research & Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of C...
STUDY OBJECTIVE
s: To examine the effects of low arterial BP (ABP) during reperfusion on the extent of myocardial infarction and on coronary blood flow (CBF) in an occlusion/reperfusion experimental model.
DESIGN
Prospective, randomized animal study.
SETTING
University hospital.
PARTICIPANTS
Normal pigs that were anesthetized, intubated, and mechanically ventilated.
INTERVENTIONS
Twenty-seven open-chest pigs underwent occlusion of the mid left anterior descending (LAD) coronary artery for 1 h followed by reperfusion for 2 h. During reperfusion, the animals were randomly assigned to either continuous infusion of nitroglycerin in therapeutic doses and fluid infusion at rates to maintain a mean AB...
MEASUREMENTS AND RESULTS
The hemodynamics and the coronary ABP distal to the occlusion were recorded throughout the experiment. In addition, the LAD CBF and peak hyperemia CBF before occlusion and during reperfusion periods were measured by transit-time flowmetry. At the end of the experiment, the infarcted left ventricular myocardial size was...
CONCLUSIONS
Low ABP during reperfusion increases the size of myocardial infarction and decreases CBF.Retrovirus-neutralizing antibodies in AML and AMMoL patients: stage-specific distribution.
Plasma samples of patients with AML or AMMoL were tested for antibodies reacting with gp70 antigens of BaEV and GaLV as well as for antibodies neutralizing BaEV or GaLV. Both frequency and titer values of antibodies were higher in remission than in blastosis. Neutralizing activity could be detected only in those plasma...
Complement activation plays a major role in many acute and chronic inflammatory conditions. C3d, a terminal product of complement activation, remains covalently attached to cells and is an excellent biomarker of complement-mediated inflammation. We employed a virtual high-throughput screening protocol to identify molec...
BACKGROUND & AIMS
Heregulins (HRGs) regulate the proliferation and differentiation of various cell types. However, very little is known about their function in the gastrointestinal tract. The aim of this study was to investigate the role of HRGs on gastrointestinal cells.
METHODS
We examined the expression of erbB receptors and HRG-alpha in human gastric cancer cell lines, rat gastrointestinal epithelial cells, and human gastric fibroblasts by Western blot analysis or reverse-transcription polymerase chain reaction. Receptor phosphorylation and heterodimerization induced by HRG-alpha were detec...
RESULTS
Cancer cell lines and rat epithelial cells expressed erbB2 and erbB3, but protein expression of erbB4 was not detected. HRG-alpha was detected only in gastric fibroblasts. HRG-alpha activated tyrosine phosphorylation of epidermal growth factor receptor (EGFR), erbB2, and erbB3 and induced not only erbB3/erbB2 but also ...
CONCLUSIONS
The data suggest that HRG-alpha may affect epithelial cell proliferation through mesenchymal-epithelial interaction in the gastric mucosa.Role of base G-2 of pre-tRNAfMet in cleavage site selection by Escherichia coli RNase P in vitro.
In this study, a protocol for the purification of fully active Escherichia coli RNase P holoenzyme from a strain overproducing both the C5 protein and the M1 RNA components is described. A total of 0. 8 mg of homogeneous enzyme, with a 1:1 protein/RNA subunit stoichiometry, was recovered from a 1 L bacterial culture. I...
Background: DBA/2FG-pcy (pcy) mice harbor a homozygous Nphp3 missense mutation and develop nephronophthisis with renal interstitial fibrosis. Previous studies have shown that aberrant oxygen homeostasis contributes to the renal pathology in pcy mice, but the underlying molecular mechanism remains largely unknown. Metho...
Samur-Absheron Canal is one of the important waterways of Azerbaijan. It provides filling the Jeyranbatan reservoir with water and makes it possible to irrigate the vast territories of the Absheron region and the coastal lands of five districts of the north–eastern region. The Jeyranbatan reservoir, in turn, is the mai...
To investigate the pharmacokinetics and pharmacodynamics of a new angiotensin converting enzyme (ACE) inhibitor, ramipril (HOE 498), in patients with cardiac insufficiency (NYHA III-IV), we performed an open trial with a follow-up of 10 days. Twenty-seven patients (18 females, 9 males), mean aged 62 years (46–83) with ...
Object tracking is still a critical and challenging problem in computer vision. More and more researchers pay attention to applying deep learning to obtain the powerful feature for robust tracking. Nowadays, feature fusion is an essential part of Siamese tracking architectures. However, the existing feature fusion meth...
This study investigates the relationship between emotional intelligence and social anxiety levels of university students. The study data consisted of a total of 212 university students, 64% female (N=136) and 36% (N=76) male and data were collected from a state university in the west of Turkey. The relational model, on...
Aims and Background The quantification and molecular characterization of circulating free DNA (cfDNA) have attracted much interest as new and promising, noninvasive means of detecting and monitoring the presence of surgical resectable colorectal cancer (CRC). Instead, the role of cfDNA in the early detection of maligna...
Abstract Let σ() denote the number of automorphisms of a model of power ω1. We derive a necessary and sufficient condition in terms of trees for the existence of an with . We study the sufficiency of some conditions for . These conditions are analogous to conditions studied by D. Kueker in connection with countable mod...
Aim. The evaluation of donor’s duodenum histological examination in diagnosis of pancreaticoduodenal graft rejection.Materials and methods. The 35-yo patient with terminal diabetic nephropathy undergone simultaneous retroperitoneal kidney and pancreas transplantation  with enteric exocrine drainage of the graft via int...
Modelling of high-frequency circuits and interconnects described by tabulated multi-port parameters has generated immense interest during recent years. In most cases, equivalent circuit models (ECM) are available to the designers, which correlate well with the measured parameters at low frequencies, however, deviate at...
Background: The improvement of maternal health and reduction of maternal mortality have been a priority on the global community’s agenda. In this sense, the “plan of action to accelerate the reduction of maternal mortality and severe maternal morbidity” has focused on improving women’s health and attempted to contribut...
The Reginald Taylor Essay Prize, first awarded in 1934, was originally awarded on an annual basis, more recently biennially, for the best unpublished essay submitted on any subject of arthistorical, archaeological or antiquarian interest within the period from the Roman era to ad 1830, whenever such an essay was adjudg...
Summary. Erythrocyte‐associated IgG was measured on washed red cells from 26 children with P. falciparum parasitaemia using an immunoradiometric assay. The values obtained were compared with 15 age‐matched controls living in the same area who did not have malaria. The amount of red cell‐associated IgG was related to th...
The propagation of an electron-acoustic wave in a plasma consisting of two types of ion and two temperature electrons has been investigated in the linear and nonlinear regimes. The presence of the second species of ion modifies the characteristics of the wave. The analysis has been done for both the finite amplitude an...
We prospectively followed 61 children under 15 years of age at the time of diagnosis to identify the risk factors for deformity progression. The children had 63 lesions and a minimum of 15 years followup. All exhibited an increase in deformity during the active disease phase, but 26 of 63 (41%) continued to progress du...
The purpose of this article is to review the dominant paradigms and thinking behind periodontal diagnosis and treatment over the last 150 years, including the clinical characteristics paradigm, the classical pathology paradigm, and the infection/ host response paradigm, and to predict what changes may occur in the next...
Single crystals of ferroelectric triglycine sulfate (TGS) have been grown from aqueous solution containing 10 mol% of sarcosine. The crystal, referred to as SarTGS, shows a quite different habit from undoped TGS. The concentration of sarcosine incorporated in the crystal is, at most, 1/500 of the solution concentration...
The objective of this paper is to present a systematic approach to feature vector extraction for the automatic classification of power quality (PQ) disturbances, where discrete wavelet transform (DWT), signal power estimation and data compression methods are utilized to improve the classification performance and reduce...
Large numbers of Atlantic salmon (Salmo salar) are used as research animals in basic research and to solve challenges related to the fish-farming industry. Most of this research is performed on farmed animals provided by local breeders or national breeding companies. The genetic constitution of these animals is usually...
An 8-month-old neutered male Manx-type cat was evaluated because of clear fluid that had been draining from a skin mass dorsocaudal to the sacrum for 1 week. Neurologically, the cat had poor postural reactions and poor withdrawal reflexes in the hind limbs. Ultrasonography of the dorsal sacral area revealed a 3-cm-long...
We present experimental results on the provision of multiple units of a threshold public good using individualized price auctions (IPA). The IPA asks each individual to pay the same price for each unit provided. The individual’s price can be either one’s bid or one’s pivotal price on the marginal unit provided by the g...