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A 43-year-old woman with a complaint of facial swelling was admitted to our hospital. A chest roentgenogram revealed a mass in the mediastinum. Chest CT and MRI demonstrated a mass in the anterior mediastinum protruding into the superior vena cava (SVC) and right atrium. A diagnosis of thymoma was made by needle biopsy... |
Cell-cell communications in multicellular organisms generally involve secreted ligand-receptor (LR) interactions, which is vital for various biological phenomena. Recent advancements in single-cell RNA sequencing (scRNA-seq) have effectively resolved cellular phenotypic heterogeneity and the cell-type composition of co... |
The changing workforce may to some extent be a boon or bane to the business. Although it may not be absolute to conclude that the current changes in the workforce with regards to attitude, skills, interest and above all how the workforce deal with their fellow employees, managers, and supervisors are entirely beyond co... |
Objectives How do students transfer knowledge of lesion identification into practice? This question regarding correct diagnosis and management of prosthetic skin lesions [benign nevus (BN) or melanoma (M)] were studied in fourth-year medical students during a Clinical Skills Assessment (CSA). This study tested students... |
In order to discuss the nucleation mechanism of strain rockburst, this paper takes the rockburst section of deep diversion tunnel of Jinping Hydropower Project of Yalong River as the research object. Through the study of microseismic monitoring technology and the regularity of microseismic parameters, as well as combi... |
Do soap operas serve a purpose? Do they need to? In 1950 an everyday story of farming folk was launched on the wireless to educate the rural community of the Midlands in matters pertaining to agriculture and animal husbandry. The Archers subsequently became a national institution; one discussed and debated by rural and... |
In the field of Global Navigation Satellite System (GNSS), jamming signals are more than ever a real threat, demanding for an increasing need of countermeasures. Among several proposed detection and mitigation methods developed for specific types of interference, the Adaptive Notch Filter (ANF) is still an attractive s... |
The aim of the doctoral study outlined in this paper is to contribute to the improvement of teaching and learning of environmental education. The significance of environmental education as a strategy to address environmental problems has been documented widely in Australia and overseas. This study shows that as a strat... |
In a forest inventory context, estimation for small areas and for remote and inaccessible regions may be problematic using traditional probability- or design-based inference because acquisition of sufficiently large samples to satisfy precision requirements is financially and/or logistically difficult. These problems c... |
Background Prostate cancer and stromal hyperplasia (SH) in the transition zone (TZ) are difficult to discriminate by conventional magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI). Purpose To investigate the apparent diffusion coefficient (ADC) of prostate cancer and SH in the TZ with histogram anal... |
In search for the historical examples to mobilize the masses for the anti-colonial struggle, during the period from 1918 to 1948 Arab public, political and religious fi gures regularly appealed to the history of the Crusades. They developed the interpretations proposed by public and religious fi gures of the 19th – ear... |
The recurring devastation caused by extreme events underscores the need for reliable estimates of their intensity and frequency. Operational frequency and intensity estimates are very often obtained from generalized extreme value (GEV) distributions fitted to samples of annual maxima. GEV distributed random variables a... |
The authors report a case of intra-abdominal testicular torsion, where laparoscopy has been useful for diagnosis and surgical management. A boy was presented with a left impalpable testis. Laparoscopy revealed a twisted spermatic cord at the inlet pelvis, which ended in a testicular remnant located in the sub-umbilical... |
We derive approximate expressions for the dispersion relation of the nonlinear Klein-Gordon equation in the case of strong nonlinearities using a method based on the linear delta expansion. All the results obtained in this article are fully analytical, never involve the use of special functions, and can be used to obta... |
Seeks to assess maternity care for women with Type 1 diabetes in relation to recommendations in a national clinical guideline using a criterion-based clinical audit. The audit covered all 22 consultant-led maternity units in Scotland, focusing on 268 completed pregnancies in women with Type 1 diabetes. Results are pres... |
In order to overcome the current network security problems in the process of smart city construction and improve the accuracy of smart city network security evaluation, this paper proposes a novel smart city network security evaluation system. The evaluation system comprehensively and systematically analyzes the curren... |
Mitochondria isolated from Kalanchoë daigremontiana, a Crassulacean acid metabolism plant, decarboxylate added malate to pyruvate at rates of up to 100 micromoles per hour per milligram original chlorophyll in the presence of ADP. Omitting ADP reduces this rate by approximately 50%. Antimycin A inhibits malate decarbox... |
This review aimed to synthesize current evidence on family involvement in pain management for people living with dementia from the perceptions of family carers and health care professionals. An integrative review was conducted using CINAHL, Embase, PubMed, PsycINFO and Cochrane Library electronic databases. The Mixed M... |
Equality and efficiency are key issues in educational reform. Here the authors analyze the efficiency and equality consequences of various school finance reforms using a cost-indirect output distance function. This function readily models multiple-output production under conditions of budgetary constraint, and provides... |
introductory remarks on historical ecology and state formation in southern Africa Shadreck Chirikure, Per Ditlef Fredriksen and Munyaradzi Manyanga Materials Laboratory, Department of Archaeology, University of Cape Town, Rondebosch, 7700, South Africa; Department of Archaeology, Conservation and History, University of... |
SummarySince the 1960s, numerous studies on sugarcane plant regeneration have been reported. Essentially, successful culture and regeneration of plants from protoplasts, cells, callus, and various tissue and organs, have been achieved in this crop. Although plant regeneration from callus cultures had been reported sinc... |
OBJECTIVE |
To determine the relative risk reduction associated with prophylactic knee braces in the prevention of knee injuries in collegiate football players. |
DATA SOURCES |
An exhaustive search for original research was performed using the PubMed, SportDiscus, and CINAHL databases from 1970 through November 2006, with the search terms knee brace, knee braces, knee bracing and football, prophylactic brace, and prophylactic knee braces. |
STUDY SELECTION |
Seven studies comparing knee injuries among braced and non-braced collegiate football players were included. Study methods were assessed using the Physiotherapy Evidence Database (PEDro) scale. PEDro scores ranged from 2 to 5. |
DATA EXTRACTION |
The number of participants and frequency of knee injuries were used to calculate the relative risk reduction or increase. |
DATA SYNTHESIS |
We found a relative risk reduction for 3 studies with point estimates of 10% (36% to -26%), 58% (25% to 76%), and 56% (13% to 77%). Four studies demonstrated an increased risk of injury, with point estimates of 17% (19% to -71%), 49% (-31% to -69%), 114% (23% to -492%), and 42% (-18% to -70%). |
CONCLUSIONS |
Data from existing research are inconsistent. Based on a Strength of Recommendation Taxonomy level of evidence of 2 with a grade B recommendation, we cannot conclusively advocate or discourage the use of prophylactic knee braces in the prevention of knee injuries in collegiate football players.Professional Nursing Burn... |
This expanded (n = 648) replication study examines job-related burnout in practicing nurses in relation to five maladaptive thinking patterns at eight northeast Florida hospitals. Data supported the hypothesis that maladaptive thinking patterns may be related to nurses’ burnout thoughts and behaviors. The focus of this... |
In this paper, the author examines the historical evolution in the United States of the use of the term “present fairly” in the auditor’s report, as well as the experience and arguments in the United States and Canada regarding the use of a “two-part” opinion in the report. He then develops an argument for the adoption... |
The dating of past landslide events is one of the most crucial aspects of landslide research, leading to a better understanding of past landslide activity. Landslides can be extremely dangerous natural hazards, and thus, solving the relationships between their activity and climate variations is of high importance. For ... |
PURPOSE |
To assess the dialysability of iobitridol, a comparative study with iohexol was conducted in the rat over 4 hours. |
MATERIAL AND METHODS |
After ligature of the renal veins and arteries, a group of animals was submitted to continuous peritoneal dialysis, while the remainder were not. |
RESULTS |
In the event of total renal failure, biliary excretion rose from 0.4 to 9% for iobitridol and from 2 to 16% for iohexol. In the rats submitted to peritoneal dialysis, biliary excretion decreased to 5% in the iobitridol group and to 13% in the iohexol group. Further, 18% of the test substances were eliminated in the dia... |
CONCLUSIONS |
As their physicochemical characteristics are very similar, the differences between the biliary excretion levels of these 2 media may be caused by a factor related to their respective molecular conformations.Aspergillus endocarditis in children: case report and review of the literature. |
Aspergillus fumigatus endocarditis developed in a 2 1/2-year-old girl after repair of tetralogy of Fallot. There have been 14 other cases of Aspergillus endocarditis in children described in the literature. Fever and embolic phenomenon, particularly to the CNS, were the most common presenting manifestations. Consumptiv... |
Estimation of soil moisture distribution in desert regions is challenged by the deep unsaturated zone and the extreme natural environment. In this study, an entropy-based method, consisting of information entropy, principle of maximum entropy (PME), solutions to PME with constraints, and the determination of parameters... |
The immunoglobulin G Fc receptors (FcγRs) play an important role in mediating the effector function of IgG. The expression ratio of activating and inhibitory FcγRs determines the threshold for cellular activation. Previous studies have suggested dysregulation of FcγR expression on monocytes and B cells in patients with... |
Background: Gastrointestinal Stromal Tumors (GIST) treatment was revolutionized by the introduction of the tyrosine kinase inhibitor imatinib. More recently, sunitinib, has prolonged survival in patients (pts) with metastatic disease resistant to imatinib. 10-year survival for high-risk pts treated with adjuvant imati... |
Methods: Demographic data and treatment indications were reported by treating physicians. The clinical status of each enrolled pt was reviewed with TMF every 3-4 months. Pts who were lost to follow-up (LTFU) (n=2282) with metastatic or unresectable disease were presumed to be deceased. Alternatively, for patients trea... |
Results: The median age at diagnosis was 54 and 55 years in the adjuvant and metastatic groups, respectively. Males comprised 59.5% of all metastatic/unresectable cases and females 51.3% of adjuvant cases. Median OS for pts treated with imatinib for unresectable or metastatic disease was 5.8 years (CI: (5.6, 6.1)) and... |
Discussion: This is the largest known cohort of GIST outcomes and the first study to present outcomes from predominantly low- and middle-income countries. Additionally, studies in LMICs are challenged by high rates of lost to follow-up which can falsely prolong or shorten survival times due to censoring. Therefore, we... |
Citation Format: Edward Lloyd Briercheck, J. Michael Wrigglesworth, Philip Stevenson, Alicia A. Annamalay, Pat Garcia-Gonzalez, Michael Wagner. Outcomes of an expanded access program for patients with gastrointestinal stromal tumors in low- and middle-income countries [abstract]. In: Proceedings of the American Associ... |
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