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Background: Kechuangping mixture (KCPM) based on Maxingshigan decoction has a significant clinical effect in the treatment of pediatric pneumonia, especially for asthmatic pneumonia. This study explored the effects of KCPM on lipopolysaccharide (LPS)-induced macrophage immune response and the molecular mechanism invol... |
Nursing is identified as a profession because it requires both extensive education in science and specialized training. But simply working in an identified profession does not automatically make one a professional. Professionalism involves much more than degrees and credentials. It includes a certain work ethic, attitu... |
In order to plan services for long-term care of those with acquired brain injury (ABI), the prevalence of ABI was investigated by using a postal inquiry sent to a representative sample of general practitioners, of whom 121 cooperated and registered 186 cases. The corresponding estimated prevalence of adults with ABI-re... |
While retention of highly qualified employees is vital for professional services firms, prior research has largely neglected the role of customers as a driver of employee satisfaction and retention. Drawing on an experimental study and a dyadic field study, this article shows that client satisfaction is an important de... |
A vast amount of literature exists pertaining to female coaches at all levels of competition from around the globe. Within this article, using Brofenbrenner's ecological systems theory, the complex and multidimensional barriers that affect, impede or prevent females from seeking or remaining in coaching positions, in a... |
“Coal is, perhaps, the most indispensable article used by man. Without it, in time, we should return to a state of barbarism.” So proclaimed the president of Pennsylvania's Pequa Railroad and Improvement Company in 1849. The importance of coal, the official explained, lay in its utility as an energy source, for which h... |
The modern way of all society spheres development is sustainable and encourages the integration of the scientific processes. The transfer of ideas and research methods from one scientific area to another through the cognitive potential of different disciplines reflects this tendency. All these processes lead to a colla... |
Despite oxycodone's (4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one) history of clinical use and the attention it has received as a drug of abuse, few reports have documented its pharmacology's relevance to its abuse or its mechanism of action. The purposes of the present study were to further characterize the... |
Multiple (four or eight) electrode arrays were placed for simultaneous electro-olfactogram (EOG) recordings of responses to a series of odors applied directly to the olfactory epithelium. Three different surfaces of the epithelium were exposed in rats immediately after death by anesthetic overdose. We tested three terp... |
The classical action of a two dimensional N = 2 supersymmetric theory, characterized by a general Kähler potential, is written down on a non(anti)commutative superspace. The action has a power series expansion in terms of the determinant of the non(anti)commutativity parameter C αβ. The theory is explicitly shown to pr... |
Atomic force microscopy nanolithography (AFM) is a strong fabrication method for micro and nano structure due to its high spatial resolution and positioning abilities. Mixing AFM nanolithography with advantage of silicon-on-insulator (SOI) technology provides the opportunity to achieve more reliable Si nanostructures. ... |
The aim of present study was to assess the frequency of violence against married women and its related factors in health centers affiliated to Isfahan University of medical sciences.This is a cross-sectional study was conducted on married women who were attending in health centers in Isfahan city, Iran. Woman Abuse sca... |
An analysis of isoenzymes of glucose-6-phosphage dehydrogenase (G-6-P-DH) and lactage dehydrogenase (LDH) of continuous cells from the collection of Sverdlovsk Research Institute of Virus Infections was carried out. Seventeen continous human and animal cell lines were examined by electrophoresis in a vertical block of ... |
In their meritorious communications 1 Dr Lloyd and Professor Stein have drawn attention to the role which Roman law played in the exposition of Calvin's theory of resistance. This theory of Calvin's was in all its essentials firmly grounded in the antecedent medieval and ecclesiastical doctrines relative to public gove... |
Background: Clonidine is an α2-agonist that is commonly used for sedation in the intensive care unit. When patients are on continuous venovenous hemofiltration (CVVH) in the presence of kidney dysfunction, the sieving coefficient of clonidine is required to estimate how much drug is removed by CVVH. In the present stud... |
How to automatically spot the major trends in large amounts of heterogeneous data? Clustering can help. However, most existing techniques suffer from one or more of the following drawbacks: 1) Many techniques support only one particular data type, most commonly numerical attributes. 2) Other techniques do not support a... |
Abstract We measured hemolymph Na+ and K+ concentrations, gut Na+ and K+ concentrations, transepithelial electrical potentials (TEPs) and fluxes of Na+, K+ and water for the insectivorous praying mantis Tenodora sinensis (Orthoptera: Mantidae). In addition, we calculated transepithelial potential differences for Na+ (E... |
Abstract. Optical burst switching (OBS) is a technique involving a switched mechanism for upcoming all-optical backhauls. However, data bursting congestion may occur as a considerable problem due to the increasing amount of light passing through interconnections and the overall system range. Moreover, the lack of restr... |
The light out-coupling efficiency of organic light-emitting devices was enhanced using microlens arrays fabricated by a direct printing technique. The high surface-free energy of a glass substrate was modified through the use of a hydrophobic silane coupling agent thus achieving a high contact angle for liquid droplets... |
Imagine an office environment equipped with infrared presence sensors for light control as modern buildings offer. Several persons might be moving in this environment independently from each other. Potential questions arising here are: Which rooms are occupied?", "How many persons are in room 123?", or "Where is John?"... |
With the proliferation of social media, cyber threats and attacks have significantly increased in complexity and quantity in financial market. Malicious hackers leverage the influence of social media to spread deceptive information with an intent to gain abnormal profits illegally or to cause losses. Measuring informat... |
Abstract. Penstemon haydenii Wats. (blowout penstemon, blowout beardtongue) is an early-succession plant species that is adapted to the dynamic habitats found in sand dunes. Following widespread habitat loss, the species was thought to be extinct from 1940 until it was rediscovered in 1968. It was listed as endangered ... |
The 1990s brought an abundance of reports on paclitaxel-producing endophytes, initially heralded as a discovery having tremendous implications for cancer therapy. As the vision of large-scale fermentation tanks producing vast quantities of relatively inexpensive paclitaxel and novel taxanes has faded and has been repla... |
Abstract In this paper we consider first-order systems with constant coefficients for two real-valued functions of two real variables. This is both a problem in itself, as well as an alternative view of the classical linear partial differential equations of second order with constant coefficients. The classification of... |
Textile-based humidity sensors can be an important component of smart wearable electronic-textiles and have potential applications in the management of wounds, bed-wetting, and skin pathologies or for microclimate control in clothing. Here, we report a wearable textile-based humidity sensor for the first time using hig... |
Why are notions about voice and race that are no longer supported by research still reproduced? Through ethnography work on classical vocal training in southern California in the early twenty-first century, this article demonstrates that listeners—teacher and audiences—project intention and identity onto vocal timbres ... |
Rationale: Despite overwhelming evidence of the importance of brain renin–angiotensin system (RAS), the very existence of intrinsic brain RAS remains controversial. Objective: To investigate the hypothesis that the brain (pro)renin receptor (PRR) is physiologically important in the brain RAS regulation and cardiovascul... |
Various forms of true pemphigus have been reported to occur with myasthenia gravis, with and without thymoma, more frequently than can be ascribed to chance. A57-year-old woman with myasthenia gravis in remission developed pemphigus foliaceus. No roentgenologic evidence of a thymoma was present. Antinuclear antibodies ... |
This article discusses the law, policy and procedure of legal professional privilege in EU antitrust enforcement. It focuses primarily on the enforcement of Articles 101 and 102 TFEU [Treaty on the Functioning of the European Union] by the European Commission, but also touches briefly on the enforcement of EU antitrust... |
Stress is known to inhibit granule cell proliferation in the hippocampus. However, recent studies suggest that the commonly used dose of bromodeoxyuridine (BrdU) is insufficient to label all fractions of granule cells. Furthermore, stress-induced changes in BrdU availability may influence the labeling of newly born cel... |
Electron energy loss vibrational spectroscopy (EELS) and thermal desorption mass spectrometry (TDMS) have been used to investigate the chemisorption of several molecules on the hexagonally close-packed Ru(001) surface. The adsorption of N 2 , O 2 , and N 2 with O 2 and CO was investigated to characterize the chemical s... |
We report a case of a brain abscess identified on fluorine-18 choline (FCH) positron emission tomography (PET) scan, which was not identified on fluorodeoxyglucose (FDG) PET scan. To our knowledge, there are no previous case reports of incidental brain abscess identified by FCH PET imaging. A 51-year-old man, with live... |
In the present study, we show that intact Mycoplasma fermentans cells have a wealth of adhesive interactions with components of the extracellular matrix. Mycoplasma fermentans intensively bind plasminogen, and to a lesser extent, fibronectin, heparin, and laminin. The binding of collagen type III, IV, or V was low. The... |
An efficient copper-catalyzed tandem regioselective cis-carbometallation/cyclization of imine-ynamides with arylboronic acids has been developed. This method leads to a facile and practical synthesis of valuable 2,3-disubstituted indolines in moderate to excellent yields and features a broad substrate scope and wide fu... |
The cause of pull-in voltage shift during lifetime test of RF MEMS ohmic switches is explored. During lifetime test, the pull-in voltage of RF MEMS ohmic switches is observed to increase with lifetime test cycles. In order to determine possible causes, two steps are performed. The first is to estimate the effect of cyc... |
BACKGROUND |
Pancreatic cancer is closely related to epigenetic abnormality. The epithelial cell transforming sequence 2 gene (ECT2) plays a critical role in Rho activation during cytokinesis, and thus may play a role in the pathogenesis of pancreatic cancer. In this study, we investigated the relationships between aberrant express... |
METHODS |
Four cell lines (PANC-1, Colo357, T3M-4 and PancTuI) and pancreatic ductal adenocarcinoma (PDAC) tissues were used for mRNA detection. After restriction isoschizomer endonucleases (MspI/HpaII) were used to digest the DNA sequence (5'-CCGG-3'), PCR was made to amplify the product. And RT-PCR was applied to determine the... |
RESULTS |
The mRNA expression of the ECT2 gene was higher in pancreatic tumor tissue than in normal tissue. The gene was also expressed in the 4 PDAC cell lines. The methylation states of the upstream regions of the ECT2 gene were almost identical in normal, tumor pancreatic tissues, and the 4 PDAC cell lines. Some of the 5'-CCG... |
CONCLUSIONS |
The oncogene ECT2 is overexpressed in pancreatic tumor tissues as verified by RT-PCR detection. The methylation status of DNA in promoter areas is involved in the gene expression, along with other factors, in pancreatic cancer.ALTERNATIVE POLICIES TO DEAL WITH LABOR SURPLUSES DURING THE CUBAN TRANSITION |
1. This is a revised version of the longer paper presented at the 1996 ASCE Annual Meetings. Some portions of this study appeared in an earlier paper, “Planning for a Free Market Labor Force in Post-Transition Cuba,” presented at the Allied Social Science Association meetings in San Francisco, California, January 4-7, ... |
MANETs have specific features that can satisfy the mobility and heterogeneous requirement of the smart environment. Smart applications need high Mobility, Bandwidth, Reliability and less Packet Loss and Delays; therefore, it is important to provide good Quality of Service (QoS) in such applications. So there is a dire ... |
T H E EXPERIENCE-RATING provisions of 50 State unemployment insurance laws operated during 1947 to reduce by almost half the amount that would have been collectible at the standard tax rate. War-risk contributions, which in 1943, 1944, and 1945 had counteracted the experience-rating reductions to some extent, were not ... |
This paper investigates the effects on labour supply, consumption and savings of a change in the superannuation tax structure, involving the taxation of contributions to a fund, pre-retirement earnings of the fund, and the benefits received from the fund during retirement. The effects on lifetime plans of tax changes a... |
Three aspects of iron metabolism were studies in reticulocytes from iron-deficient, phlebotomized, and phenylhydrazine-treated rats: (1) the number of transferrin binding sites; (2) the uptake of 59Fe-transferrin; and (3) the ability of cytosol to mobilize 59Fe from 59Fe-labeled reticulocyte plasma membrane. The number... |
Aim and objective: The aim of present research work is to develop validated RP-HPLC stability indicating method for the quantification of Diroximel Fumarate in bulk and its pharmaceutical dosage forms. Materials and methods: Chromatographic method was carried on C18 column (Waters 250mm x 4.6mm, 5m). Mobile phase was p... |
Introduction and objectives There is increasing interest in the role of eosinophils in the pathogenesis of COPD. We know that in stable COPD, patients a with raised blood eosinophil count benefit more from inhaled corticosteroids than patients with lower blood eosinophil counts. A raised blood eosinophil count has also... |
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