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afterwards , the author has called to mind the notion of tumoral ecology and the various possibilities of inhibition of the tumoral growth , that is founded on the inhibition of the angiogenesis and the therapeutical possibilities of the t.a.f . in the fight against cancer .
nichd_parent_of
{ "id": "C0027651", "name": "tumoral", "pos": [ 57, 64 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 267, 273 ] }
data from normal glands , graves ' goiters , non toxic multinodular goiters and nodular and perinodular tissue of toxic nodular goiters show the same basal , tsh- and naf- stimulated adenylate cyclase activities ( no . = 45 ; 34.1 +/- 3.2 ( m +/- se ) , 378 +/- 43 , 298 +/- 48 pmol camp x min-1 x mg membrane protein-1 ...
nichd_parent_of
{ "id": "C0018021", "name": "goiters", "pos": [ 35, 42 ] }
{ "id": "C0342127", "name": "toxic nodular goiters", "pos": [ 114, 135 ] }
an older brother may have had a similar disease , suggesting a possible genetic basis for the disorder .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 40, 47 ] }
{ "id": "C0019247", "name": "genetic", "pos": [ 72, 79 ] }
[ investigation and evaluation of some physical features of composite materials based on observation of surfaces shaped under a glass cover ] .
nichd_parent_of
{ "id": "C0220825", "name": "investigation", "pos": [ 2, 15 ] }
{ "id": "C0031809", "name": "evaluation", "pos": [ 20, 30 ] }
for modern acute poisoning management there are several therapeutic transfusion-induced methods ( forced diuresis , haemodialysis , peritoneal dialysis , haemoperfusion , plasmapheresis , exsanguino-transfusion , blood and blood component transfusion , intravenous solution infusion etc ) , each of them having their adv...
nichd_parent_of
{ "id": "C0087111", "name": "therapeutic", "pos": [ 56, 67 ] }
{ "id": "C0005841", "name": "blood component transfusion", "pos": [ 223, 250 ] }
biological behaviour of two sublines of mammary cancer susceptible strains made free of mammary tumour virus ( mtv ) by foster-nursing .
nichd_parent_of
{ "id": "C0004927", "name": "behaviour", "pos": [ 11, 20 ] }
{ "id": "C0006147", "name": "nursing", "pos": [ 127, 134 ] }
on the basis of this study it is concluded that ro 10-9359 is a promising drug for the treatment of several skin diseases , specially ichthyosis , darier 's disease , oral lichen planus , erythrokeratoderma variabilis and psoriasis .
nichd_parent_of
{ "id": "C0037274", "name": "of", "pos": [ 13, 15 ] }
{ "id": "C0020757", "name": "ichthyosis", "pos": [ 134, 144 ] }
on the basis of this study it is concluded that ro 10-9359 is a promising drug for the treatment of several skin diseases , specially ichthyosis , darier 's disease , oral lichen planus , erythrokeratoderma variabilis and psoriasis .
nichd_parent_of
{ "id": "C0037274", "name": "of", "pos": [ 13, 15 ] }
{ "id": "C0033860", "name": "psoriasis", "pos": [ 222, 231 ] }
among those children seen again at the age of 18 mth fine-motor adaptive performance was poorer for infants in group a than in groups b ( p > 0.05 ) , c ( p > 0.005 ) and d ( p > 0.01 ) .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 12, 20 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 100, 107 ] }
since the procedure may have value in preventing progression of these complications , it should be evaluated in patients with less advanced complications of diabetes .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 10, 19 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 99, 108 ] }
instead , special teachers were assigned to provide individual and group guidance for gifted children at various grade levels , without isolating these children from their normal classroom environment .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 52, 62 ] }
{ "id": "C0008059", "name": "children", "pos": [ 152, 160 ] }
although , from this limited number of studies no satisfactory interpretation of the pathogenesis of acute renal failure can be deduced from the structural changes found , the findings do indicate that hypoxia plays a key role in aggravating the structural changes that induce permanent cell damage in man following shoc...
nichd_parent_of
{ "id": "C0036974", "name": "shock", "pos": [ 316, 321 ] }
{ "id": "C0036983", "name": "septic shock", "pos": [ 354, 366 ] }
the findings indicate that poverty in childhood and adolescence , followed by later prosperity , results in high cholesterol values .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 38, 47 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 52, 63 ] }
effect of pyridoxine on pituitary release of growth hormone and prolactin in childhood and adolescence .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 77, 86 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 91, 102 ] }
wegener 's granulomatosis is a systemic disease characterized by a clinical triad of paranasal sinus and nasal mucosa involvement , pulmonary infiltration and cavitation , and renal disease with hematuria .
nichd_parent_of
{ "id": "C0022658", "name": "renal disease", "pos": [ 176, 189 ] }
{ "id": "C0018965", "name": "hematuria", "pos": [ 195, 204 ] }
the muller 's muscle-conjunctival resection procedure has advantages over the fasanella operation because tarsus is preserved , and over the levator aponeurosis advancement and tuck operation because the results are more predictable .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 44, 53 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 182, 191 ] }
the procedure is an excellent and predictable operation if the criteria which have been advocated by many authors are carefully followed .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 46, 55 ] }
anatomical resectability , potential of control by radiation , disability and deformity produced by surgery , presence of metastases , psychological factors , and concurrent disease , as well as tumour behaviour , are all factors which influence the choice of radiation or surgery , alone , or in combination , in the tr...
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 174, 181 ] }
{ "id": "C0027651", "name": "tumour", "pos": [ 195, 201 ] }
the device combines certain features of predecessor interometers but in a module which , subject to limitations on path-length and bandwidth , is simpler to use .
nichd_parent_of
{ "id": "C1521970", "name": "features", "pos": [ 28, 36 ] }
{ "id": "C1444754", "name": "length", "pos": [ 120, 126 ] }
additional features of the processing method include : instantaneous full correction for tunnel free stream velocity and temperature fluctuations , first-order correction for dc drifts of the signals during data acquisition , subtraction of all 60-hz related noise , and correction for streamwise displacement of sensors...
nichd_parent_of
{ "id": "C1521970", "name": "features", "pos": [ 11, 19 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 121, 132 ] }
the method is simple , rapid and quantitative over a wide range of acidity ( 1-4n sulphuric acid ) and is superior to existing gravimetric methods .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 33, 45 ] }
{ "id": "C1514721", "name": "range", "pos": [ 58, 63 ] }
for the 9r12 laser line , we find a ( 12 ) cf ( 4 ) feature located 30 +/- 3 mhz to the high-frequency side of line center , with a peak absorption coefficient of 5 x 10 ( -4 ) to 9 x 10 ( -4 ) cm ( -1 ) torr ( -1 ) , depending on temperature .
nichd_parent_of
{ "id": "C1521970", "name": "feature", "pos": [ 52, 59 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 231, 242 ] }
performance characteristics are given for 4 x 4-mm bolometers designed for operation at both ( 4 ) he and ( 3 ) he temperatures .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 12, 27 ] }
{ "id": "C0039476", "name": "temperatures", "pos": [ 115, 127 ] }
by small-signal analysis of the rate equations it is found that the height of the resonancelike peak in the modulation characteristics is a minimum when the transverse width in which both the light and the carriers are confined is around the diffusion length .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 119, 134 ] }
{ "id": "C1444754", "name": "length", "pos": [ 252, 258 ] }
the procedure is used for the investigation of the low order resonant vibration modes of four cylinders of various sizes and materials with shear-diaphragm end conditions with good results .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0220825", "name": "investigation", "pos": [ 30, 43 ] }
three selection treatments were conducted for 12 generations in each of two base populations ( p and q ) : ( 1 ) increased nursing ability of the mother ( n12 ) , as measured by mean 12-day weight of eight young within a crossfostering set ( m ( p ) and m ( q ) lines ) , ( 2 ) increased adult ( 42-day ) body weight of ...
nichd_parent_of
{ "id": "C0004927", "name": "conducted", "pos": [ 32, 41 ] }
{ "id": "C0006147", "name": "nursing", "pos": [ 123, 130 ] }
the significance of a helicopter patrol procedure directed toward prevention of home burglaries was evaluated from experimental and cost-benefit perspectives .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 40, 49 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 100, 109 ] }
the child 's and parent 's perceptions of the network , of the people available to help the child , and the child 's friends are compared within the context of ecological , socioeconomic , and maturational factors .
nichd_parent_of
{ "id": "C0027361", "name": "people", "pos": [ 63, 69 ] }
{ "id": "C0008059", "name": "child 's", "pos": [ 108, 116 ] }
soft somatic tissue sarcomas seem to have a much better five-year survival rate than the corresponding bone sarcoma ( 60 % vs 0 % ) .
nichd_parent_of
{ "id": "C1261473", "name": "soft", "pos": [ 0, 4 ] }
{ "id": "C0029463", "name": "bone sarcoma", "pos": [ 103, 115 ] }
[ respiratory disorders during heine-medin disease ; clinical characteristics and therapeutic indications ; description of two cases of pulmonary atelectasis ] .
nichd_parent_of
{ "id": "C0035204", "name": "respiratory disorders", "pos": [ 2, 23 ] }
{ "id": "C0004144", "name": "pulmonary atelectasis", "pos": [ 136, 157 ] }
the significance of two varieties of fluid accumulation in patients with vascular headache of the migraine type .
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 82, 90 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 98, 106 ] }
[ urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with various endocrine diseases ( addison 's disease , cushing 's disease , cushing 's syndrome , precocious puberty caused by congenital adrenal hyperplasia , acromegaly ) ] .
nichd_parent_of
{ "id": "C0014130", "name": "endocrine diseases", "pos": [ 93, 111 ] }
{ "id": "C0010481", "name": "cushing 's", "pos": [ 156, 166 ] }
[ urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with various endocrine diseases ( addison 's disease , cushing 's disease , cushing 's syndrome , precocious puberty caused by congenital adrenal hyperplasia , acromegaly ) ] .
nichd_parent_of
{ "id": "C0014130", "name": "endocrine diseases", "pos": [ 93, 111 ] }
{ "id": "C0001206", "name": "acromegaly", "pos": [ 240, 250 ] }
[ psychoses and the thyroid ; behavior of protein-bound iodine and cholesterol in the blood in mental disorders and the effect of electroshock , insulin coma , prefrontal lobotomy and sleep therapy ] .
nichd_parent_of
{ "id": "C0004927", "name": "behavior", "pos": [ 30, 38 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 184, 189 ] }
in a reliability study concerning axis v ( abnormal psychosocial situations ) of the multiaxial classification scheme for psychiatric disorders in childhood and adolescence , it was found that the level of agreement in scoring was adequate for only 2 out of 12 categories .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 147, 156 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 161, 172 ] }
since toxoplasma organisms may be isolated within a few days in tissue culture , it is proposed that this method should be used when early isolation of the parasite is crucial for the diagnosis of toxoplasmosis .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 17, 26 ] }
{ "id": "C0030498", "name": "parasite", "pos": [ 156, 164 ] }
a total of 322 single and paired serum samples from children ( newborn to 10 years old ) , young adults ( 18 to 20 years old ) , pregnant women and their cord serum samples , and elderly people ( more than 70 years old ) was tested for antibodies to enteric adenovirus types 40 and 41 by neutralization test .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 52, 60 ] }
{ "id": "C0021289", "name": "newborn", "pos": [ 63, 70 ] }
the wi61 virus was clearly distinguished by cross-neutralization tests from human rotaviruses of serotypes 1 , 2 , 3 , and 4 , human 69m , and representative bovine ( ncdv ) , porcine ( osu ) , and chicken ( ch2 ) rotaviruses .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 9, 14 ] }
{ "id": "C0035870", "name": "rotaviruses", "pos": [ 214, 225 ] }
the emergence of this organism as an occasional pathogen in leukemic patients is of interest and illustrates the importance of obtaining fungal cultures .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 22, 30 ] }
{ "id": "C0450254", "name": "pathogen", "pos": [ 48, 56 ] }
the emergence of this organism as an occasional pathogen in leukemic patients is of interest and illustrates the importance of obtaining fungal cultures .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 22, 30 ] }
{ "id": "C0016832", "name": "fungal", "pos": [ 137, 143 ] }
this was the first case without any apparent underlying immunocompromising disease , and the patient was the first adult to survive the infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 75, 82 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 136, 145 ] }
however , regardless of the hepatic ct finding , biopsy should be obtained to establish the diagnosis and begin proper treatment .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 39, 46 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 92, 101 ] }
a rare case of paget sarcoma ( osteogenic sarcoma ) of the facial bones is also presented .
nichd_parent_of
{ "id": "C1261473", "name": "sarcoma", "pos": [ 21, 28 ] }
{ "id": "C0029463", "name": "osteogenic sarcoma", "pos": [ 31, 49 ] }
closed scaling and root planing has limitations as a definitive procedure for the removal of calculus from deep pockets and surgical treatment may be indicated for nonresponding sites .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 64, 73 ] }
{ "id": "C0543467", "name": "surgical treatment", "pos": [ 124, 142 ] }
furthermore , the directors were asked to state the types of questions asked most frequently , the rationale for asking those questions , and the procedure used to evaluate applicants ' responses .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 146, 155 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 164, 172 ] }
this case reconfirms the existence of typical multiple sclerosis ( ms ) in childhood , beginning even in infancy .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 75, 84 ] }
{ "id": "C0231330", "name": "infancy", "pos": [ 105, 112 ] }
therapists specializing in the rehabilitation of persons with upper extremity disorders -- hand therapists -- have developed an evaluation procedure to determine if and when an injured worker has the physical capacity to safely return to work .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation procedure", "pos": [ 128, 148 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 200, 208 ] }
the return to work evaluation has five components : ( 1 ) physical evaluation , ( 2 ) subjective effects of injury interview , ( 3 ) biomechanical job analysis , ( 4 ) work stimulation , ( 5 ) reevaluation .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 19, 29 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 58, 66 ] }
disease-free and tumour-bearing animals were entered in an effort to assess the response of canine lymphoproliferative disorders as well .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 0, 7 ] }
{ "id": "C0027651", "name": "tumour", "pos": [ 17, 23 ] }
arrhythmia analysis was valid for mean heart rate and ventricular arrhythmias , but showed lower sensitivities in detection of low prevalence ( 1-60 b/hr ) ventricular couplets ( 72 % ) and ventricular tachycardia ( 43 % ) .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmia", "pos": [ 0, 10 ] }
{ "id": "C0085612", "name": "ventricular", "pos": [ 190, 201 ] }
arrhythmia analysis was valid for mean heart rate and ventricular arrhythmias , but showed lower sensitivities in detection of low prevalence ( 1-60 b/hr ) ventricular couplets ( 72 % ) and ventricular tachycardia ( 43 % ) .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular", "pos": [ 54, 65 ] }
{ "id": "C0042514", "name": "ventricular tachycardia", "pos": [ 190, 213 ] }
most of the diseases considered , including diabetes , hypertension , myocardial infarction and other heart disease , haemorrhoids or varices , chronic respiratory disease , anaemias , gastroduodenal ulcer , cholelithiasis and liver cirrhosis , kidney and urological diseases , arthritis , and psychiatric and neurologic...
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 12, 20 ] }
{ "id": "C0042075", "name": "urological diseases", "pos": [ 256, 275 ] }
both vzv igg antibody production and t lymphocyte proliferation to vzv were detected after immunization with infectious vzv and with vzv proteins .
nichd_parent_of
{ "id": "C0042776", "name": "vzv", "pos": [ 5, 8 ] }
{ "id": "C0042338", "name": "vzv", "pos": [ 133, 136 ] }
intracranial hemorrhage was by far the most frequent presenting symptom and intraventricular hemorrhage occurred in 11 cases , with multiple episodes being documented in five .
nichd_parent_of
{ "id": "C0151699", "name": "intracranial hemorrhage", "pos": [ 0, 23 ] }
{ "id": "C0240059", "name": "intraventricular hemorrhage", "pos": [ 76, 103 ] }
underlying recipient heart disease was ischemic in three patients , congenital in two , cardiomyopathic in two , and rheumatic in one patient .
nichd_parent_of
{ "id": "C0018799", "name": "heart disease", "pos": [ 21, 34 ] }
{ "id": "C0878544", "name": "cardiomyopathic", "pos": [ 88, 103 ] }
the procedure of choice by which surgical access is gained has traditionally been a tracheostomy .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 33, 41 ] }
the suture fistula technique for long gap esophageal atresia with tracheoesophageal fistula ( tef ) was described by shafer and david in 1974 .
nichd_parent_of
{ "id": "C0016169", "name": "fistula", "pos": [ 11, 18 ] }
{ "id": "C0040588", "name": "tracheoesophageal fistula", "pos": [ 66, 91 ] }
this was the result of increased passage of antibiotic into colv , i-k94+ organisms because the plasmid effect was abolished in bacteria which had been made permeable by chemical treatment .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 74, 83 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 128, 136 ] }
recognition of such patterns assists the otolaryngologist in selecting appropriate medical or surgical treatment for the individual child .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 121, 131 ] }
{ "id": "C0008059", "name": "child", "pos": [ 132, 137 ] }
of 47 children diagnosed as having epididymitis between 1975 and 1985 , 8 of 17 prepubertal patients ( 47 per cent , or 17 per cent of the total group ) , including 3 of 4 infants ( 75 per cent ) , had an underlying urogenital anomaly .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 6, 14 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 172, 179 ] }
these results were significantly better ( p less than 0.01 ) by life-table analysis than the late stroke rate after carotid endarterectomy performed to treat anterior motor transient ischemic attacks at both ucsd and scripps clinic , as well as the reported late follow-up for all transient ischemic attacks after caroti...
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 98, 104 ] }
{ "id": "C0007787", "name": "transient ischemic attacks", "pos": [ 281, 307 ] }
a coagulopathy due to vitamin k deficiency was discovered in 42 hospitalized patients , most of whom had been misdiagnosed as having disseminated intravascular coagulation .
nichd_parent_of
{ "id": "C0005779", "name": "coagulopathy", "pos": [ 2, 14 ] }
{ "id": "C0012739", "name": "disseminated", "pos": [ 133, 145 ] }
the second major finding of this study was the unexpectedly low rate of complications ( 10 % ) which was found in both hospitals .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 17, 24 ] }
{ "id": "C0009566", "name": "complications", "pos": [ 72, 85 ] }
[ disorders of the hemodynamics and myocardial structure in patients with infectious-allergic myocarditis complicated by heart failure ] .
nichd_parent_of
{ "id": "C0012634", "name": "disorders", "pos": [ 2, 11 ] }
{ "id": "C0009450", "name": "infectious", "pos": [ 74, 84 ] }
the theoretical knowledge resulting from these studies can be used for the interpretation of the serodiagnostic tumor test with apathogenic clostridia as well as for the quantitative assessment of the malignancy of neoplastic growth .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 112, 117 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 201, 211 ] }
patterns of pulmonary arterial anatomy and blood supply in complex congenital heart disease with pulmonary atresia .
nichd_parent_of
{ "id": "C0152021", "name": "congenital", "pos": [ 67, 77 ] }
{ "id": "C0242855", "name": "pulmonary atresia", "pos": [ 97, 114 ] }
this degree of blood pressure correlation is insufficient to allow accurate prediction of subsequent blood pressure levels on the basis of a single casual blood pressure measurement in an individual child .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 188, 198 ] }
{ "id": "C0008059", "name": "child", "pos": [ 199, 204 ] }
the diagnostic value of mr contrast between renal cortex and medulla ( cmc ) as an indicator of renal disease was retrospectively studied in 51 patients ( 9 patients with obstructive disease , 7 with inflammatory disease , 12 with various noninfectious parenchymal medical disease , 5 with vascular disease , 2 with diff...
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 102, 109 ] }
{ "id": "C0027651", "name": "neoplastic disease", "pos": [ 324, 342 ] }
the organism capable of maximum zinc accumulation was identified as an enterobacter species and intracellular zinc deposition by this micro-organism was determined using energy dispersive x-ray analysis , transmission electron microscopy and a metal-staining technique at the light microscopy level .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 4, 12 ] }
{ "id": "C0445623", "name": "micro-organism", "pos": [ 134, 148 ] }
consequently , 131i-mibg therapy is recommended even if the spread of disease is not proved-only , however , when the tumor is small .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 70, 77 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 118, 123 ] }
the diagnostic techniques are medical history , physical examination , allergy skin tests or in vitro tests for ige antibody and correlation of improvement in symptoms with animal avoidance .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic techniques", "pos": [ 4, 25 ] }
{ "id": "C0022885", "name": "tests", "pos": [ 102, 107 ] }
a procedure is devised for simple graphical evaluation of the association constant for antibody-antigen interactions from data obtained by conventional solid-phase immunoassay for antigen .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 2, 11 ] }
{ "id": "C0220825", "name": "evaluation", "pos": [ 44, 54 ] }
tumors arising from bronchial epithelia in childhood and adolescence are very uncommon , ossification in this age group is a rarity .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 43, 52 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 57, 68 ] }
we have compared the frequencies of chromosomal aberrations in skin fibroblasts from persons with down 's syndrome ( trisomy 21 ) with those from normal diploid controls exposed to 60co gamma-radiation in vitro .
nichd_parent_of
{ "id": "C0008625", "name": "chromosomal aberrations", "pos": [ 36, 59 ] }
{ "id": "C0013080", "name": "trisomy 21", "pos": [ 117, 127 ] }
clinical signs of infection included erythema , induration , and cutaneous or subcutaneous necrosis at the point of entry into the subclavian vein , in the subcutaneous tunnel , or at the exit site from the skin .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0041834", "name": "erythema", "pos": [ 37, 45 ] }
clinical signs of infection included erythema , induration , and cutaneous or subcutaneous necrosis at the point of entry into the subclavian vein , in the subcutaneous tunnel , or at the exit site from the skin .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0332534", "name": "induration", "pos": [ 48, 58 ] }
the authors describe a patient aged 22 years in whom a developmental anomaly was found with fusion of the vertebral bodies c4 through c6 , posterior spina bifida from c5 through th1 and meningocele at the level c4 through c7 .
nichd_parent_of
{ "id": "C0080178", "name": "spina bifida", "pos": [ 149, 161 ] }
{ "id": "C0009730", "name": "meningocele", "pos": [ 186, 197 ] }
the intraventricular injection ( 0.1-1 nmol ) of ( - ) 3ppp [ 3- ( 3-hydroxyphenyl ) n-n-propylpiperidine ] , a specific agonist at dopamine ( da ) autoreceptors , produced dose-dependent behavioural sedation or sleep and an increase in ecog spectrum power , with a predominant increase in the lower frequency bands .
nichd_parent_of
{ "id": "C0004927", "name": "behavioural", "pos": [ 188, 199 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 212, 217 ] }
it has been postulated that anomalous cerebral dominance is associated with disorders of the immune system and increased incidence of autoimmune diseases has been reported in left-handed individuals .
nichd_parent_of
{ "id": "C0021053", "name": "disorders of the immune system", "pos": [ 76, 106 ] }
{ "id": "C0004364", "name": "autoimmune diseases", "pos": [ 134, 153 ] }
dental disease prevention activity , center for prevention svcs , hospital infections program , center for infectious diseases , cdc .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 7, 14 ] }
{ "id": "C0009450", "name": "infectious diseases", "pos": [ 107, 126 ] }
logistic regression analysis revealed that meconium , maternal fever ( caused by urinary tract infection , upper respiratory infection , chorioamnionitis , and unknown causes ) , maternal anemia ( caused by abruptio placentae , placenta previa , and unknown causes ) , and maternal pulmonary disease ( caused by asthma a...
nichd_parent_of
{ "id": "C0024115", "name": "pulmonary disease", "pos": [ 282, 299 ] }
{ "id": "C0032285", "name": "pneumonia", "pos": [ 326, 335 ] }
four patients are disease-free at 13+ to 48+ months , one patient is alive with disease at six+ months , and three patients are dead of tumor at four , 17 , and 36 months from the start of chemotherapy .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 18, 25 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 136, 141 ] }
this case is an example of unexpected clinical findings that may be encountered in any iris melanocytic lesion , benign or malignant , and the consequent problems of diagnosis and management .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 38, 55 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 166, 175 ] }
surgical therapy of glaucoma was required in 24 % of those with glaucoma and was most effective as cyclodestructive surgery especially in patients with progressive angle-closure glaucoma .
nichd_parent_of
{ "id": "C0017601", "name": "glaucoma", "pos": [ 20, 28 ] }
{ "id": "C0017605", "name": "angle-closure glaucoma", "pos": [ 164, 186 ] }
new equipment and individuals specifically trained to work with children now permit the evaluation of even young children .
nichd_parent_of
{ "id": "C0027361", "name": "individuals", "pos": [ 18, 29 ] }
{ "id": "C0008059", "name": "children", "pos": [ 113, 121 ] }
we confirmed our previous observation of increased respiratory bandwidth , an index of variability in respiratory frequency ( p = 0.009 ) but failed to confirm our finding of increased low frequency fluctuations in heart rate ( p = 0.18 ) .
nichd_parent_of
{ "id": "C0425442", "name": "observation", "pos": [ 26, 37 ] }
{ "id": "C0231832", "name": "respiratory frequency", "pos": [ 102, 123 ] }
a total of 265 echocardiograms were performed in 210 children with malignant neoplasms and leukemia from 1981 to 1985 and 12 cases ( 5.7 % ) of p.e . were identified : 7 affected by acute lymphatic leukemia ( all ) , 3 rhabdomyosarcoma , 1 by wilm 's tumor and 1 by ewing 's sarcoma .
nichd_parent_of
{ "id": "C0006826", "name": "malignant neoplasms", "pos": [ 67, 86 ] }
{ "id": "C0027708", "name": "wilm 's tumor", "pos": [ 243, 256 ] }
juvenile osteoporosis should be regarded as a polyetiological disease developing against the background of constitutional osteopathy in which endocrine disorders play a certain role .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 62, 69 ] }
{ "id": "C0014130", "name": "endocrine disorders", "pos": [ 142, 161 ] }
patients with hypogonadism should be examined with respect to anosmia because such a combination suggests the diagnosis of kallmann 's syndrome .
nichd_parent_of
{ "id": "C0020619", "name": "hypogonadism", "pos": [ 14, 26 ] }
{ "id": "C0162809", "name": "kallmann 's syndrome", "pos": [ 123, 143 ] }
the incidence of nephritis in autoimmune new zealand black ( nzb ) mice is low , but when they are crossed with normal swr mice , almost 100 % of the female f1 hybrids ( snf1 ) develop lethal glomerulonephritis .
nichd_parent_of
{ "id": "C0027697", "name": "nephritis", "pos": [ 17, 26 ] }
{ "id": "C0017658", "name": "glomerulonephritis", "pos": [ 192, 210 ] }
whether il-2 alone can have significant antitumor activity may depend on factors such as tumor bulk , the patient 's inherent ability to generate cytotoxic cells or the susceptibility of a particular malignancy .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 44, 49 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 200, 210 ] }
these results demonstrate that the fluid and cellular responses in rat pleural inflammation can be differentially regulated by anti-inflammatory drugs depending upon the doses of antigen and antibody employed in rpar pleurisy and the identity of the inflammatory stimulus .
nichd_parent_of
{ "id": "C0005889", "name": "fluid", "pos": [ 35, 40 ] }
{ "id": "C0003241", "name": "antibody", "pos": [ 191, 199 ] }
on the basis of leonhard 's classification of the endogenous psychoses an attempt is made to trace the phenomenology of the monopolar and bipolar affective psychoses as well as leonhard 's `` '' unsystematic schizophrenias '' '' to three different functional anomalies .
nichd_parent_of
{ "id": "C0004936", "name": "psychoses", "pos": [ 61, 70 ] }
{ "id": "C0005586", "name": "bipolar affective", "pos": [ 138, 155 ] }
alcohol as a risk factor for injuries or death due to fires and burns : review of the literature .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 29, 37 ] }
{ "id": "C0006434", "name": "burns", "pos": [ 64, 69 ] }
the findings in 32 studies on alcohol and injuries and deaths attributed to fires and burns were analyzed in detail .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 42, 50 ] }
{ "id": "C0006434", "name": "burns", "pos": [ 86, 91 ] }
and for many antibodies , there is a strong dependency of tumor uptake on total mass amount of antibody administered ( greater uptake with greater mass dose ) .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 58, 63 ] }
{ "id": "C0577559", "name": "mass", "pos": [ 147, 151 ] }
in order to assess the efficiency of this therapy approach , we used the mopo scales , a thoroughly evaluated instrument describing patient health status in both its physical and psychosocial dimensions .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 100, 109 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 166, 174 ] }
the oxygenation characteristics of the five components , measured in relation to ph , temperature and the erythrocytic ligand 2,3-diphosphoglycerate ( dpg ) , together with the changes in their relative concentrations during early embryonic life , are given .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 16, 31 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 86, 97 ] }
all began their lgs in childhood or infancy ( between the ages of 1 and 8.80 p. 100 before the age of 4 ) .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 23, 32 ] }
{ "id": "C0231330", "name": "infancy", "pos": [ 36, 43 ] }
quantitative analysis is then usually carried out with the peak-to-local background method : by taking the background in the same energy range as the characteristic peak , an intrinsic correction for absorption of x-rays within the sample is made .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 0, 12 ] }
{ "id": "C1514721", "name": "range", "pos": [ 137, 142 ] }