text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
it is found that economic growth plays a principal role in reducing mortality at nearly all ages , and specifically mortality due to total cardiovascular disease , cerebrovascular disease , total heart disease , ischemic heart disease , total malignancies , disorders of infancy , and motor vehicle accidents . | nichd_parent_of | {
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"name": "cardiovascular disease",
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} | {
"id": "C0018799",
"name": "heart disease",
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} |
all people receiving these drugs in ethiopia should be tested serologically for syphilis , however , as eight ( 11.8 % ) of 68 men in this study also had active latent syphilis . | nichd_parent_of | {
"id": "C0039128",
"name": "syphilis",
"pos": [
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} | {
"id": "C0039133",
"name": "latent syphilis",
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thus , in the acute phase of unstable cad , the platelet sensitivity to the inhibitory effects of prostacyclin was reduced which might contribute to the risk for further platelet aggregation , coronary occlusion and myocardial infarction . | nichd_parent_of | {
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} | {
"id": "C0027051",
"name": "myocardial infarction",
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although natural killer cells are thought to play a major role in surveillance against tumor development , no systemic studies on natural killer cells and their activities have been reported in familial polyposis coli in which cancer always develops at an early age . | nichd_parent_of | {
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} | {
"id": "C0006826",
"name": "cancer",
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of 594 injuries those of the upper extremities were predominant followed by mostly severe head injuries . | nichd_parent_of | {
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"name": "injuries",
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} | {
"id": "C0018674",
"name": "head injuries",
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the spectrophotometric readings of the elisa procedure were evaluated on the basis of the arithmetical mean ( means ) and standard deviation ( sd ) of the values obtained in negative controls . | nichd_parent_of | {
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the virus was re-isolated from tonsillar swabs from two animals on post-infection day ( pid ) 3 . | nichd_parent_of | {
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"id": "C0242172",
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the partial sequence information allowed us to ( 1 ) identify numerous geographic foci of endemic circulation of wild type 1 polioviruses , ( 2 ) reveal previously unsuspected links between cases in distant communities , ( 3 ) monitor the displacement from the environment of preexisting polioviruses by viruses from oth... | nichd_parent_of | {
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} | {
"id": "C0206435",
"name": "polioviruses",
"pos": [
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this report presents a procedure for evaluating the relative affinities of simple sialoside receptor determinants for their interaction with the receptor binding pocket of the influenza virus hemagglutinin . | nichd_parent_of | {
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these antigens were able to induce both the slow type hypersensitivity and the reaction related apparently to the later phase of immediate hypersensitivity . | nichd_parent_of | {
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"id": "C0020523",
"name": "immediate hypersensitivity",
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content of muscular proteins in blood reflected the response of muscle system to physical exercises and may serve as a criterion in evaluation of various steps of adaptation to physical loading . | nichd_parent_of | {
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} | {
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we calculated new birthweight , length and head circumference standards for caucasian boys and girls between 26 and 43 weeks gestation from 28,126 singleton live births at our hospital between 1980 and 1985 . | nichd_parent_of | {
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"name": "length",
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} | {
"id": "C0262499",
"name": "head circumference",
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although one organism of parent nk65 could kill one mouse , as many as 10 ( 7 ) xat parasites caused modest self limiting parasitaemia in immuno-competent mice . | nichd_parent_of | {
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} | {
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factors associated with a favorable prognosis for survival and cure of infection include prompt surgical treatment , complete graft removal , staged graft removal and revascularization , and autogenous reconstructions when feasible . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical treatment",
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} | {
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} |
pituitary adenomas obtained at selective transsphenoidal adenomectomy from a patient with prolactinoma , and two patients with mixed gh- and prl-secreting pituitary adenomas were cultured in monolayer . | nichd_parent_of | {
"id": "C0032000",
"name": "pituitary adenomas",
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} | {
"id": "C0033375",
"name": "prl-secreting pituitary adenomas",
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141,
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} |
the aim of the present study was to clarify the effect of leukaemia treatment on neuroendocrine control of prl secretion in long-term survivors of acute lymphoblastic leukaemia ( all ) . | nichd_parent_of | {
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"name": "effect",
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} | {
"id": "C0023449",
"name": "acute lymphoblastic leukaemia",
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176
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} |
rupture of the distal tibiofibular syndesmosis without fracture of the fibula may be a rare event , but in the presence of certain clinical signs , it should be investigated ( pain and haematoma above the syndesmosis , pain at eversion and dorsal flexion , history of dislocation of the joint ) . | nichd_parent_of | {
"id": "C3540840",
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"pos": [
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} | {
"id": "C0030193",
"name": "pain",
"pos": [
219,
223
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} |
among fungi , the most numerous were strains of the genus penicillium ( 39.4 % ) , yeasts ( 29.5 % ) and strains of the genus aspergillus ( 8.4 % ) . | nichd_parent_of | {
"id": "C0016832",
"name": "fungi",
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} | {
"id": "C0043393",
"name": "yeasts",
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} |
the viral infections , specially infectious mononucleosis and hepatitis b can cause urticaria , mostly chronic , although infrequently produces cold urticaria . | nichd_parent_of | {
"id": "C0042769",
"name": "viral infections",
"pos": [
4,
20
]
} | {
"id": "C0021345",
"name": "infectious mononucleosis",
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33,
57
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} |
the viral infections , specially infectious mononucleosis and hepatitis b can cause urticaria , mostly chronic , although infrequently produces cold urticaria . | nichd_parent_of | {
"id": "C0042769",
"name": "viral infections",
"pos": [
4,
20
]
} | {
"id": "C0019163",
"name": "hepatitis b",
"pos": [
62,
73
]
} |
symptomatic patients can be managed either by symptom alleviation , as in benign arrhythmia , or more aggressively , as in malignant ventricular arrhythmia . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmia",
"pos": [
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91
]
} | {
"id": "C0085612",
"name": "ventricular arrhythmia",
"pos": [
133,
155
]
} |
the cases described here may represent a subset of patients with sle in whom expression of lupus nephritis was altered by the concomitant hbv-related glomerulonephritis . | nichd_parent_of | {
"id": "C0027697",
"name": "nephritis",
"pos": [
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]
} | {
"id": "C0017658",
"name": "glomerulonephritis",
"pos": [
150,
168
]
} |
despite the overall association between increasing parity and lower risk , the women with many late pregnancies and those with few , widely spaced pregnancies had higher risk than nulliparous women , indicating that both the age when pregnancy occurs and the length of intervals between successive births may modify the ... | nichd_parent_of | {
"id": "C0030563",
"name": "parity",
"pos": [
51,
57
]
} | {
"id": "C0425979",
"name": "nulliparous",
"pos": [
180,
191
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} |
further , since unsaturated somatomedin carrier proteins can interfere with the assay and in vitro biologic actions of the igfs , and since there was more unsaturated carrier protein binding of igf-1 by the sera of 15 children with renal disease v 15 normal children ( 17 +/- 3 % v 12 +/- 3 % binding of [ 125i ] -igf-1/... | nichd_parent_of | {
"id": "C0022658",
"name": "renal disease",
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]
} | {
"id": "C0022661",
"name": "chronic renal failure",
"pos": [
474,
495
]
} |
the study proved that raynaud 's phenomenon without an underlying cause must be followed up for more than two years , contrary to what was recommended previously , before it can be rightly diagnosed as primary raynaud 's phenomenon . | nichd_parent_of | {
"id": "C0034735",
"name": "raynaud 's phenomenon",
"pos": [
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} | {
"id": "C0151445",
"name": "primary raynaud 's phenomenon",
"pos": [
202,
231
]
} |
in this study , the evaluation included history and clinical examination , tests for antinuclear antibodies , radiography of hands , chest roentgenography , and nailfold capillary microscopy . | nichd_parent_of | {
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"name": "evaluation",
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30
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} | {
"id": "C0031809",
"name": "clinical examination",
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} |
histologically , acute and chronic inflammation with focal suppurative infiltrates of phagocytosed fat was detected in the absence of vascular or embolic disease , infection , or other apparent cause . | nichd_parent_of | {
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"name": "disease",
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} | {
"id": "C0009450",
"name": "infection",
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} |
combinations of various measures and characteristics analyzed by the multiple regression technique explained only 30 % of the overall variability in blood pressure . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
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52
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} | {
"id": "C0005823",
"name": "blood pressure",
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149,
163
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} |
we followed up 32 eyes of 32 patients with early glaucoma ( 22 with capsular glaucoma and ten with simple glaucoma ) who received laser trabeculoplasty as a primary therapy . | nichd_parent_of | {
"id": "C0017601",
"name": "glaucoma",
"pos": [
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57
]
} | {
"id": "C0017612",
"name": "simple glaucoma",
"pos": [
99,
114
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} |
the synthesis of stromal collagens by sarcomas but not neural tumors serves to distinguish these two tumor types , especially ewing 's sarcoma from neuroblastoma . | nichd_parent_of | {
"id": "C1261473",
"name": "sarcomas",
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46
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} | {
"id": "C0553580",
"name": "ewing 's sarcoma",
"pos": [
126,
142
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} |
this study considers measurements of weight , recumbent length , head circumference , triceps skinfold , and arm circumference of 1,100 infants aged 7 to 13 months from a cross-sectional sample representative of the u.s. infant population . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
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62
]
} | {
"id": "C0262499",
"name": "head",
"pos": [
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69
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} |
however , in multiple regressions , these anthropometric characteristics failed to account fully for the greater relative weight of mexames as compared to eurames . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
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} | {
"id": "C0005910",
"name": "weight",
"pos": [
122,
128
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} |
we conclude that the mechanisms responsible for behavioral sleep states are responsive to a sleep-promoting substance early in ontogenesis . | nichd_parent_of | {
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} | {
"id": "C0037313",
"name": "sleep",
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} |
the following eight abdominal complications required operation : wound dehiscence ( four instances ) , small bowel obstruction ( one instance ) , mallory-weiss tear ( one instance ) , gastrostomy tube leak ( one instance ) , and acute gastric dilatation ( one instance ) . | nichd_parent_of | {
"id": "C0009566",
"name": "complications",
"pos": [
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43
]
} | {
"id": "C0259768",
"name": "wound dehiscence",
"pos": [
65,
81
]
} |
five renal injuries were demonstrated by cect in patients with negative eu : one contusion , one subcapsular hematoma , two perirenal hematomas , and one renal laceration . | nichd_parent_of | {
"id": "C0018944",
"name": "hematoma",
"pos": [
109,
117
]
} | {
"id": "C0473124",
"name": "perirenal hematomas",
"pos": [
124,
143
]
} |
one dog died of disease unrelated to the tumor , and one dog was euthanatized after the surgery . | nichd_parent_of | {
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"name": "disease",
"pos": [
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23
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
41,
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]
} |
evaluation of joints in which physical defects were made revealed no differences between control and psg-injected joints . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluation",
"pos": [
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} | {
"id": "C0031809",
"name": "physical",
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} |
twenty cows from a dairy herd consisting of 60 healthy , lactating holsteins developed clinical signs of anorexia , mental derangement , dehydration , recumbency , and ruminal atony after ingesting water containing blue-green algae . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
87,
101
]
} | {
"id": "C0003123",
"name": "anorexia",
"pos": [
105,
113
]
} |
the value of hba1 and fructosamine in predicting impaired glucose tolerance -- an alternative to ogtt to detect diabetes mellitus or gestational diabetes . | nichd_parent_of | {
"id": "C0011849",
"name": "diabetes mellitus",
"pos": [
112,
129
]
} | {
"id": "C0085207",
"name": "gestational diabetes",
"pos": [
133,
153
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} |
the response to the standard 75 g oral glucose tolerance test was used to confirm or reject the diagnosis , using different criteria for detection of diabetes mellitus compared to detection of gestational diabetes . | nichd_parent_of | {
"id": "C0011849",
"name": "diabetes mellitus",
"pos": [
150,
167
]
} | {
"id": "C0085207",
"name": "gestational",
"pos": [
193,
204
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} |
the cohorts of children who left the channel they had been following included fat infants with a late rebound who subsequently returned to normal , and lean infants with an early rebound who grew fatter . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
15,
23
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
157,
164
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} |
the results indicated that pb intoxication in neonates and children may be a significant health problem in kuwait , and that measurement of blood zpp can be used as a simple , rapid , and inexpensive microscreening method for pb poisoning in infants and neonates . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
59,
67
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} | {
"id": "C0021270",
"name": "infants",
"pos": [
242,
249
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} |
the results indicated that pb intoxication in neonates and children may be a significant health problem in kuwait , and that measurement of blood zpp can be used as a simple , rapid , and inexpensive microscreening method for pb poisoning in infants and neonates . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
59,
67
]
} | {
"id": "C0021289",
"name": "neonates",
"pos": [
254,
262
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} |
the diagnosis of this disease can be difficult as many patients present with totally asymptomatic forms which may be revealed suddenly and totally unpredictably by an episode of severe infection . | nichd_parent_of | {
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"name": "disease",
"pos": [
22,
29
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} | {
"id": "C0009450",
"name": "infection",
"pos": [
185,
194
]
} |
these two investigations together with cystography demonstrate the high incidence ( 16/55 ) of associated contralateral uropathy ( vesicoureteric reflux , megaureter , hydronephrosis ) . | nichd_parent_of | {
"id": "C0042075",
"name": "uropathy",
"pos": [
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128
]
} | {
"id": "C0042580",
"name": "vesicoureteric reflux",
"pos": [
131,
152
]
} |
a comparison of treatment routes indicated the relative efficacies as intraperitoneal greater than per os greater than intramuscular greater than or equal to subcutaneous . | nichd_parent_of | {
"id": "C0013153",
"name": "of treatment routes",
"pos": [
13,
32
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} | {
"id": "C1527415",
"name": "per os",
"pos": [
99,
105
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} |
baculovirus interaction with nontarget organisms : a virus-borne reporter gene is not expressed in two mammalian cell lines . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
39,
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} | {
"id": "C0042776",
"name": "virus",
"pos": [
53,
58
]
} |
this organism , which is pathogenic to mice , is being considered as a model for the inactivation of the human pathogen giardia lamblia . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
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13
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} | {
"id": "C0450254",
"name": "pathogen",
"pos": [
111,
119
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} |
owing perhaps to aggregation , hrv-wa appeared less susceptible to the effects of chlorine than previously reported for this virus and for the simian rotavirus sa11 . | nichd_parent_of | {
"id": "C0042776",
"name": "virus",
"pos": [
125,
130
]
} | {
"id": "C0035870",
"name": "rotavirus",
"pos": [
150,
159
]
} |
the potential use of magnetic resonance imaging ( mri ) for inflammatory muscle disorders was evaluated in 13 patients with polymyositis and dermatomyositis . | nichd_parent_of | {
"id": "C0027121",
"name": "inflammatory muscle",
"pos": [
60,
79
]
} | {
"id": "C0085655",
"name": "polymyositis",
"pos": [
124,
136
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} |
after operation , venous repair patency was evaluated by clinical examination , impedence plethysmography , and doppler ultrasonography , and contrast venography . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
44,
53
]
} | {
"id": "C0031809",
"name": "clinical examination",
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} |
it was found that ( 1 ) the operative survival rate has been 100 % over the past 20 years for children and currently is greater than 80 % in newborns in the absence of hlv/efe ; | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
94,
102
]
} | {
"id": "C0021289",
"name": "newborns",
"pos": [
141,
149
]
} |
intra individual blood pressure ( bp ) and heart rate ( hr ) variations and their possible correlation with sex and age were evaluated in 271 healthy adults , adolescents and children divided into equivalent groups of both sexes . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
6,
16
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
175,
183
]
} |
a correspondences analysis allows to establish a typology of responses : it makes appear clear differences in information according to social class , differences in concern about cvd linked namely with personal disease 's experience , differences in psychological attitudes towards cvd 's risk . | nichd_parent_of | {
"id": "C0012634",
"name": "disease 's",
"pos": [
211,
221
]
} | {
"id": "C0007222",
"name": "cvd 's",
"pos": [
282,
288
]
} |
thus rb provides interesting data on renal lesions revealing sometimes ( n = 18 ) a specific nephropathy ( most of them were a glomerulopathy ) . | nichd_parent_of | {
"id": "C0022658",
"name": "nephropathy",
"pos": [
93,
104
]
} | {
"id": "C0268731",
"name": "glomerulopathy",
"pos": [
127,
141
]
} |
this procedure should allow surgical pathologists to obtain reliable , reproducible staining of hematopoietic neoplasms in paraffin-embedded tissues . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
5,
14
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
28,
36
]
} |
this normal distribution pattern may be altered in human liver in a variety of disorders , particularly in infectious and immune diseases . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
79,
88
]
} | {
"id": "C0009450",
"name": "infectious",
"pos": [
107,
117
]
} |
this normal distribution pattern may be altered in human liver in a variety of disorders , particularly in infectious and immune diseases . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
79,
88
]
} | {
"id": "C0021053",
"name": "immune diseases",
"pos": [
122,
137
]
} |
haemodynamics and myocardial energetics were analysed in 8 patients without significant heart disease before and after application of isoproterenol and in 10 patients with dilative cardiomyopathy ( nyha ii-iii ) . | nichd_parent_of | {
"id": "C0018799",
"name": "heart disease",
"pos": [
88,
101
]
} | {
"id": "C0878544",
"name": "cardiomyopathy",
"pos": [
181,
195
]
} |
the cr1 levels differed when the jra patients were grouped by mode of disease onset and by clinical state at the time of testing ( levels in patients with pauciarticular disease were higher than those in patients with polyarticular disease , and levels in patients with polyarticular disease were higher than those in pa... | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
70,
77
]
} | {
"id": "C0442893",
"name": "systemic disease",
"pos": [
332,
348
]
} |
from the point of view of mortality , subarachnoid anaesthesia did not appear to confer any advantages over general anaesthesia in non-prosthetic surgery for hip fracture in the elderly . | nichd_parent_of | {
"id": "C0002903",
"name": "anaesthesia",
"pos": [
51,
62
]
} | {
"id": "C0002915",
"name": "general",
"pos": [
108,
115
]
} |
splenomegaly is less frequent in hb sc patients in this country and there is also a lower incidence of leg ulceration in both hb ss and hb sc disease in the united kingdom than in jamaica . | nichd_parent_of | {
"id": "C0002895",
"name": "hb ss",
"pos": [
126,
131
]
} | {
"id": "C0019034",
"name": "hb sc",
"pos": [
136,
141
]
} |
clinical and morphological studies have shown a high correlation between the appearance of the tubal mucosa and the ultimate outcome in terms of pregnancies . | nichd_parent_of | {
"id": "C0032972",
"name": "outcome",
"pos": [
125,
132
]
} | {
"id": "C0233324",
"name": "terms",
"pos": [
136,
141
]
} |
conversely , low basal levels of c-fos transcripts were found in pure acute granulocytic leukemias ( fab m1/m2/m3 ) , in erythroleukemias ( fab m6 ) , in the great majority of b , and in all t lymphoid leukemias . | nichd_parent_of | {
"id": "C0023467",
"name": "acute",
"pos": [
70,
75
]
} | {
"id": "C0023440",
"name": "fab m6",
"pos": [
140,
146
]
} |
the spectrum of diseases seen in patients from certain 'tropical areas ' requires that a physician be aware of some of the syndromes discussed here . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
16,
24
]
} | {
"id": "C0039082",
"name": "syndromes",
"pos": [
123,
132
]
} |
at the acute phase , thought-disordered subjects ( schizophrenics , manics and schizo-affectives ) were less communicable than non-thought-disordered subjects ( depressives and normals ) . | nichd_parent_of | {
"id": "C0012634",
"name": "disordered",
"pos": [
29,
39
]
} | {
"id": "C0009450",
"name": "communicable",
"pos": [
109,
121
]
} |
es is therefore an efficient procedure in high-risk patients , which facilitates operation , especially in cases of acute cholecystitis , and it is recommended in all cases of complicated biliary lithiasis . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
29,
38
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
81,
90
]
} |
the modification of bick 's procedure improves the outcome of the operation and simplifies its performance . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
28,
37
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
66,
75
]
} |
the patient may present with atypical clinical findings such as a continuous murmur or atrioventricular block , making the diagnosis difficult . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
38,
55
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
123,
132
]
} |
the current results show that tumor basement membranes and peritoneal barriers play a notable role in the transit of tumor antigens , one which must be taken into account in the monitoring of serum marker levels of cancer patients . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
30,
35
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
215,
221
]
} |
these tumors were sarcomatous histologically and thus did not resemble any human pituitary adenoma tissue injected . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
6,
12
]
} | {
"id": "C0032000",
"name": "pituitary adenoma",
"pos": [
81,
98
]
} |
the tumors therefore arose from transformed c3h 10t1/2 cells after coculture with the human pituitary adenoma cells . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
4,
10
]
} | {
"id": "C0032000",
"name": "pituitary adenoma",
"pos": [
92,
109
]
} |
since go alpha , a specific protein in the neural and neuroendocrine cells , was found to be produced in considerable amounts by all types of neuroendocrine tumors but not in nonneuroendocrine tumors , go alpha might be a useful biomarker for neuroendocrine tumors . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
157,
163
]
} | {
"id": "C0206754",
"name": "neuroendocrine tumors",
"pos": [
243,
264
]
} |
vomiting , hematemesis , and esophagitis resulting from gastroesophageal reflux or hiatal hernia are frequently observed in severely handicapped children . | nichd_parent_of | {
"id": "C0042963",
"name": "vomiting",
"pos": [
0,
8
]
} | {
"id": "C0018926",
"name": "hematemesis",
"pos": [
11,
22
]
} |
all had vomiting or hematemesis as a main symptom , and the cause of esophagitis was suggested to be gastroesophageal reflux in 13 cases and hiatal hernia in four . | nichd_parent_of | {
"id": "C0042963",
"name": "vomiting",
"pos": [
8,
16
]
} | {
"id": "C0018926",
"name": "hematemesis",
"pos": [
20,
31
]
} |
the following results were obtained : ( 1 ) improvement was seen within seven days after start of famotidine treatment , and reduction of vomiting or hematemesis or both was reached within two weeks in 70 % of cases and within three weeks in 94 % ; | nichd_parent_of | {
"id": "C0042963",
"name": "vomiting",
"pos": [
138,
146
]
} | {
"id": "C0018926",
"name": "hematemesis",
"pos": [
150,
161
]
} |
[ a comprehensive diagnostic approach to tumor metastases in the skeleton . vi . the bone marrow in the metastatic process in malignant neoplasms ] . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
41,
46
]
} | {
"id": "C0006826",
"name": "malignant neoplasms",
"pos": [
126,
145
]
} |
the 5-year survival rate and mean disease-free interval in the chemotherapy group were 76.3 % and 24.6+ months , respectively , in bladder cancer patients , and 78.2 % and 25.8+ months in those with upper urinary tract tumors . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
34,
41
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
219,
225
]
} |
the rise in alkaline phosphatase ( alp ) , leucine aminopeptidase ( lap ) , gamma-glutamyl transferase ( ggt ) and the unchanged activities in the aspartate and alanine aminotransferases ( ast , alt ) in plasma of tam-treated rats indicated that the disease induced by this substance can be considered as a chronic obstr... | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
250,
257
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
382,
388
]
} |
embolic cerebral infarctions were documented in 12 patients , one patient had evidence of intracranial hemorrhage , and one patient had a subdural hematoma . | nichd_parent_of | {
"id": "C0151699",
"name": "intracranial hemorrhage",
"pos": [
90,
113
]
} | {
"id": "C0018946",
"name": "subdural hematoma",
"pos": [
138,
155
]
} |
application of this technology to the study of human disease will help us to define and clarify the molecular pathology of many clinical disorders , provide new diagnostic tools and approaches , and , finally , will provide new therapeutic agents including gene-replacement therapy . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
53,
60
]
} | {
"id": "C0019247",
"name": "molecular",
"pos": [
100,
109
]
} |
therefore , when serum calcium is lowered by ethylene diamine tetra-acetic acid ( edta ) infusions or calcitonin injections , patients with primary hpt display enhanced secretion of pth already within the hypercalcaemic range , whereas parathyroid function remains suppressed in malignancy-associated hypercalcaemia . | nichd_parent_of | {
"id": "C0020437",
"name": "hypercalcaemic",
"pos": [
205,
219
]
} | {
"id": "C0149911",
"name": "malignancy-associated hypercalcaemia",
"pos": [
279,
315
]
} |
this problem was examined in the candidates for seizure surgery in the austin hospital comprehensive epilepsy programme , emphasis being placed on focal seizures . | nichd_parent_of | {
"id": "C0036572",
"name": "seizure",
"pos": [
48,
55
]
} | {
"id": "C0751495",
"name": "focal seizures",
"pos": [
147,
161
]
} |
we conclude that the incidence of headache is low in cervical spondylosis and that the pattern of headache has no features that distinguish it from that of tension headache , suggesting that the pathogenesis is similar . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
34,
42
]
} | {
"id": "C0033893",
"name": "tension headache",
"pos": [
156,
172
]
} |
these agents have been effective in the treatment of angina and hypertension and in the reduction of recurrence of ischemic cardiac disease , such as myocardial infarction . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
"pos": [
0,
3
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
150,
171
]
} |
malignancies most commonly metastasizing to the thyroid are malignant melanoma and carcinoma of the breast , kidney , and lung . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
0,
12
]
} | {
"id": "C0025202",
"name": "malignant melanoma",
"pos": [
60,
78
]
} |
malignancies most commonly metastasizing to the thyroid are malignant melanoma and carcinoma of the breast , kidney , and lung . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
0,
12
]
} | {
"id": "C0678222",
"name": "carcinoma of",
"pos": [
83,
95
]
} |
there are four categories of anxiety disorders : phobic disorders , anxiety states , posttraumatic stress disorders , and atypical anxiety disorders . | nichd_parent_of | {
"id": "C0003469",
"name": "anxiety",
"pos": [
29,
36
]
} | {
"id": "C0038436",
"name": "posttraumatic stress disorders",
"pos": [
85,
115
]
} |
infections with organisms handled by cell-mediated immunity would be the most predictable , but the immunoglobulin responses that are important for opsonization of invading microorganisms may also be impaired . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
16,
25
]
} | {
"id": "C0445623",
"name": "microorganisms",
"pos": [
173,
187
]
} |
three opportunistic mycoses have causative agents that are ubiquitous in nature but cause infection only in compromised hosts : aspergillosis , mucormycosis , and candidiasis . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
90,
99
]
} | {
"id": "C0004030",
"name": "aspergillosis",
"pos": [
128,
141
]
} |
when such factors are not implicated , other specific etiologies should be sought , including unusual organisms like mycobacteria , higher order bacteria , and fungi . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
102,
111
]
} | {
"id": "C0004611",
"name": "bacteria",
"pos": [
145,
153
]
} |
when such factors are not implicated , other specific etiologies should be sought , including unusual organisms like mycobacteria , higher order bacteria , and fungi . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
102,
111
]
} | {
"id": "C0016832",
"name": "fungi",
"pos": [
160,
165
]
} |
in one case there were multiple hemorrhages and in the other there was a solitary intracerebral hemorrhage . | nichd_parent_of | {
"id": "C0019080",
"name": "hemorrhages",
"pos": [
32,
43
]
} | {
"id": "C2937358",
"name": "intracerebral hemorrhage",
"pos": [
82,
106
]
} |
the finding of a subependymal giant cell astrocytoma is sometimes seen in patients with tuberous sclerosis , and the finding of a subependymal hyperdense enhancing lesion is consistent with this diagnosis . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
4,
11
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
195,
204
]
} |
the outcome of pregnancy was term delivery in 23 cases and abortion in 7 cases . | nichd_parent_of | {
"id": "C0032972",
"name": "outcome of pregnancy",
"pos": [
4,
24
]
} | {
"id": "C0156543",
"name": "abortion",
"pos": [
59,
67
]
} |
disease spectrum of yersinia enterocolitica serogroup 0:3 , the predominant cause of human infection in new york city . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
0,
7
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
91,
100
]
} |
somatosensory evoked potentials ( seps ) after median and posterior tibial nerve stimulation were studied in 172 children ranging in age from 1 day to 16 years for the purpose of obtaining normal reference values , for use in analysing pathological cases . | nichd_parent_of | {
"id": "C1514721",
"name": "ranging",
"pos": [
122,
129
]
} | {
"id": "C2698497",
"name": "normal reference values",
"pos": [
189,
212
]
} |
the sensitivity and specificity of the procedure were evaluated by indirect elisa methodology using 506 clinical isolates of organisms in this group , ten other species of anaerobic gram-negative bacilli , and three species of aerobic gram-negative bacilli . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
39,
48
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
54,
63
]
} |
however , based on our improved assay procedure , we suggest caution should be exercised in evaluating the merits of gt as a diagnostic marker for ovarian cancer . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
38,
47
]
} | {
"id": "C0220825",
"name": "evaluating",
"pos": [
92,
102
]
} |
the antigen panel consisted of the storage mites acarus siro , lepidoglyphus destructor , and tyrophagus putrescentiae , as well as other work-related allergens ( cereal grains , animal epithelia , fungi and yeasts ) , and common allergens ( house dust mite , pollens ) . | nichd_parent_of | {
"id": "C0016832",
"name": "fungi",
"pos": [
198,
203
]
} | {
"id": "C0043393",
"name": "yeasts",
"pos": [
208,
214
]
} |
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