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our patient demonstrated no evidence of multiple neurofibromatosis , as seen in classical von recklinghausen 's disease .
nichd_parent_of
{ "id": "C0162678", "name": "multiple neurofibromatosis", "pos": [ 40, 66 ] }
{ "id": "C0027831", "name": "von", "pos": [ 90, 93 ] }
rhinovirus-like characteristics , including the length of the 5 ' non-coding region and a slight -- u/ -- a imbalance in codon usage , may be related to the fact that cav-21 , like rhinoviruses , infects the upper respiratory tract .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 16, 31 ] }
{ "id": "C1444754", "name": "length", "pos": [ 48, 54 ] }
the fifth mab , 1c6 , recognized bacterial fusion proteins containing hpv-6b l1 , -16 l1 or -18 l1 using immunoblots , yet appeared hpv-16-specific when tested on infected tissue sections .
nichd_parent_of
{ "id": "C0021344", "name": "hpv", "pos": [ 70, 73 ] }
{ "id": "C0999806", "name": "hpv-16", "pos": [ 132, 138 ] }
because of the consequences of chronic hbv infection , the nauruan government has commenced a program that aims to reduce and eventually eliminate hepatitis b infection by immunizing susceptible adults and children on the island and every newborn baby .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 206, 214 ] }
{ "id": "C0021289", "name": "newborn baby", "pos": [ 239, 251 ] }
restriction fragment differences between the genomes of the oka varicella vaccine virus and american wild-type varicella-zoster virus .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 82, 87 ] }
{ "id": "C0042338", "name": "varicella-zoster virus", "pos": [ 111, 133 ] }
variants of encephalomyocarditis virus ( emcv ) , which are immunologically indistinguishable by hyperimmune serum , produce different disease syndromes in mice .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 135, 142 ] }
{ "id": "C0039082", "name": "syndromes", "pos": [ 143, 152 ] }
for instance , in icr swiss male mice , emcv-b produces no overt illness , emcv-mm produces severe neurological signs followed by death , emcv-d destroys pancreatic beta cells producing a disease syndrome resembling insulin-dependent diabetes mellitus , and emcv-k is lethal but produces no overt signs of infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 188, 195 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 196, 204 ] }
for instance , in icr swiss male mice , emcv-b produces no overt illness , emcv-mm produces severe neurological signs followed by death , emcv-d destroys pancreatic beta cells producing a disease syndrome resembling insulin-dependent diabetes mellitus , and emcv-k is lethal but produces no overt signs of infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 188, 195 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 306, 315 ] }
therefore , the persistent bacterial infection in the middle ear and/or surrounding organs such as adenoid plays possibly an important role in the delayed recovery of ome .
nichd_parent_of
{ "id": "C0029882", "name": "infection", "pos": [ 37, 46 ] }
{ "id": "C0029883", "name": "ome", "pos": [ 167, 170 ] }
we conclude that pectus excavatum may indicate the presence of an underlying heritable disorder of connective tissue such as the marfan syndrome .
nichd_parent_of
{ "id": "C0410787", "name": "of", "pos": [ 60, 62 ] }
{ "id": "C0024796", "name": "marfan syndrome", "pos": [ 129, 144 ] }
the procedure involves ( 1 ) preparing the teeth to be retained from a periodontal standpoint to reduce the possibility of contamination of the surgical site , ( 2 ) removing hopeless teeth , ( 3 ) sectioning and contouring the teeth so that the retained roots are contiguous with the crestal bone , ( 4 ) preparing and ...
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 144, 152 ] }
maximum isolates were from burns cases and environmental sampling from burns ward also grew the same organism , indicating their role as nosocomial pathogen .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 101, 109 ] }
{ "id": "C0450254", "name": "pathogen", "pos": [ 148, 156 ] }
clinical signs may vary from depression to severe shock and death , depending upon the amount of toxin ingested .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0011065", "name": "death", "pos": [ 60, 65 ] }
the arthritis impact measure scales ( aims ) have established validity and reliability in general adult populations with medically diagnosed rheumatoid arthritis .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 4, 13 ] }
{ "id": "C0003873", "name": "rheumatoid", "pos": [ 141, 151 ] }
the site-specific binding interaction of lac repressor with a symmetric operator sequence and of ecori endonuclease with its specific recognition site both exhibit a characteristic dependence of equilibrium binding constant ( kobs ) on temperature , in which kobs attains a relative maximum in the physiologically releva...
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 166, 180 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 323, 334 ] }
the loss of heterozygosity of genes on the short arm of chromosome 3 ( 3p ) in human breast carcinomas occurs in a region involved in other malignancies , including renal cell carcinoma , lung cancers , and von hippel-lindau disease .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 140, 152 ] }
{ "id": "C0007134", "name": "renal cell carcinoma", "pos": [ 165, 185 ] }
eif-2 alpha was phosphorylated in both r2-2a-2- and wild-type-virus-infected cells , indicating that poliovirus does not encode a function that blocks phosphorylation of eif-2 alpha .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 62, 67 ] }
{ "id": "C0206435", "name": "poliovirus", "pos": [ 101, 111 ] }
surgical considerations include complete tumor excision with free margins of resection and proper pathological evaluation to determine biological potential .
nichd_parent_of
{ "id": "C0543467", "name": "surgical", "pos": [ 0, 8 ] }
{ "id": "C0015250", "name": "complete", "pos": [ 32, 40 ] }
on the basis of this experience we concluded that sclerotherapy with phenol 2.5 % is a painless , highly effective , safe and economical procedure that permits one to avoid an operation , anesthesia and hospitalization .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 137, 146 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 176, 185 ] }
on the basis of this experience we concluded that sclerotherapy with phenol 2.5 % is a painless , highly effective , safe and economical procedure that permits one to avoid an operation , anesthesia and hospitalization .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 137, 146 ] }
{ "id": "C0002903", "name": "anesthesia", "pos": [ 188, 198 ] }
these data have allowed for an accurate mapping of the hospital discharge rate for urinary tract stone disease ( stone discharge rate ) in a population at risk for urolithiasis .
nichd_parent_of
{ "id": "C0042075", "name": "urinary tract", "pos": [ 83, 96 ] }
{ "id": "C0451641", "name": "urolithiasis", "pos": [ 164, 176 ] }
however , the cumulative incidence of stroke or transient ischemic attack was not statistically different in those patients with and without restenosis .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 38, 44 ] }
{ "id": "C0007787", "name": "transient ischemic attack", "pos": [ 48, 73 ] }
the sle patients with ssb/la antibody were characterized by a low prevalence of oral ulcers , a low titer for ndna antibody , and presence of the rheumatoid factor and the anti-sm antibody .
nichd_parent_of
{ "id": "C0003241", "name": "antibody", "pos": [ 29, 37 ] }
{ "id": "C0587072", "name": "anti-sm antibody", "pos": [ 172, 188 ] }
the procedure was utilized for the treatment of acute inflammation and obstructive jaundice , and this study was initiated to evaluate its utility and the potential indications .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 126, 134 ] }
in this study , we quantitated the number of intrarenal ia positive cells and t cells in nephrotoxic nephritis in rats in order to clarify the intrarenal immune actions of sairei-to on immune mediated glomerulonephritis .
nichd_parent_of
{ "id": "C0027697", "name": "nephritis", "pos": [ 101, 110 ] }
{ "id": "C0017658", "name": "glomerulonephritis", "pos": [ 201, 219 ] }
in the 6 patients , the renal tumors were diagnosable by ct and all tumors had positive findings for malignant neoplasms angiographically .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 30, 36 ] }
{ "id": "C0006826", "name": "malignant neoplasms", "pos": [ 101, 120 ] }
the leukaemia research fund data collection survey : the incidence and geographical distribution of acute myeloid leukemia .
nichd_parent_of
{ "id": "C0023418", "name": "research", "pos": [ 14, 22 ] }
{ "id": "C0023467", "name": "acute myeloid leukemia", "pos": [ 100, 122 ] }
cholesterol and ldl levels had a same behaviour , through childhood toward adolescence , with significantly higher values in males than in females .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 58, 67 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 75, 86 ] }
finally , a procedure is provided for determining when it is morally justified to deceive patients by withholding information about their diagnoses , prognoses , or about their prospective treatments .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 12, 21 ] }
{ "id": "C0087111", "name": "treatments", "pos": [ 189, 199 ] }
we believe that the current dead donor rule and the strict `` '' whole-brain '' '' definition of death are sound public policy and good ethics and should remain the cornerstone of future decisions in this field .
nichd_parent_of
{ "id": "C0011065", "name": "dead", "pos": [ 28, 32 ] }
{ "id": "C0006110", "name": "the", "pos": [ 161, 164 ] }
the neutrophil derived o2- was markedly elevated in et shock animals as well as septic shock patients but no significant change was noted in hemorrhagic shock animals or non septic shock patient .
nichd_parent_of
{ "id": "C0036974", "name": "shock", "pos": [ 55, 60 ] }
{ "id": "C0036983", "name": "septic shock", "pos": [ 174, 186 ] }
these tumors , which included lymphomas , thymomas , fibrosarcomas , angiosarcomas , hemangiomas , and neurofibrosarcomas , developed with various frequencies after latent periods of 2 to 12 months .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 6, 12 ] }
{ "id": "C0018916", "name": "hemangiomas", "pos": [ 85, 96 ] }
the association of renal and hepatic abnormalities can be found in different congenital malformation syndromes .
nichd_parent_of
{ "id": "C0000768", "name": "abnormalities", "pos": [ 37, 50 ] }
{ "id": "C1302790", "name": "congenital malformation", "pos": [ 77, 100 ] }
we conclude that dietary supplementation with cod-liver oil lowers the elevated transcapillary escape rate of albumin characteristic of patients with insulin-dependent diabetes and albuminuria , independently of its effect on blood pressure -- perhaps by decreasing vascular permeability .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 118, 132 ] }
{ "id": "C0005823", "name": "blood pressure", "pos": [ 226, 240 ] }
only after several months of observation the finding of pseudo-myotonia suggested the diagnosis of hoffmann 's syndrome during hypothyroidism .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 45, 52 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 86, 95 ] }
the most frequently occurring diseases in the tent camp were injuries ( 36 % of the patient material ) , infectious diseases ( 30 % ) often of a viral nature and physically conditioned noxae ( sunburn , solar dermatitis , burns ) .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 30, 38 ] }
{ "id": "C0009450", "name": "infectious diseases", "pos": [ 105, 124 ] }
the most frequently occurring diseases in the tent camp were injuries ( 36 % of the patient material ) , infectious diseases ( 30 % ) often of a viral nature and physically conditioned noxae ( sunburn , solar dermatitis , burns ) .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 61, 69 ] }
{ "id": "C0006434", "name": "burns", "pos": [ 222, 227 ] }
[ hereditary diseases of the eye and their relative significance among the causes of blindness and diminished vision in the pupils of boarding schools for blind and amblyopic children in uzbekistan ] .
nichd_parent_of
{ "id": "C0015397", "name": "diseases of the eye", "pos": [ 13, 32 ] }
{ "id": "C0002418", "name": "amblyopic", "pos": [ 165, 174 ] }
as many of these tumors are not removable in toto , due to their localisation , the most malignant part of the tumor may be missed and information for optimum therapeutic management is incomplete .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 17, 23 ] }
{ "id": "C0006826", "name": "malignant", "pos": [ 89, 98 ] }
non-invasive measurement of tumor glucose metabolism with ( f-18 ) -2-fluoro-2-deoxyglucose ( fdg ) and positron-emission-tomography ( pet ) may be used to evaluate tumor malignancy .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 28, 33 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 171, 181 ] }
this simple procedure allows a rapid evaluation to be made of various characteristics of the tumour , including the ploidy level , as well as a definitive assessment of nuclear phenomena including the incidence of x-chromatin bodies .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 12, 21 ] }
{ "id": "C0220825", "name": "evaluation", "pos": [ 37, 47 ] }
however , because of some peculiar characteristics of the graded-series method , the aftereffect distortions measured with this method can not be interpreted unequivocally as reflecting distortions of the perceived length of the test line .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 35, 50 ] }
{ "id": "C1444754", "name": "length", "pos": [ 215, 221 ] }
the most common causes of acute diarrhea are infections and drugs , while the most common causes of chronic diarrhea are inflammatory bowel disease , malabsorption , parasitic infections , carcinoma of the large bowel , and metabolic diseases .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 45, 55 ] }
{ "id": "C0747256", "name": "parasitic infections", "pos": [ 166, 186 ] }
noticeable disorders in the central and peripheral factors of this system and changes in the blood levels of cyclic nucleotides were observed in patients with the lactorrhea-amenorrhea syndrome .
nichd_parent_of
{ "id": "C0012634", "name": "disorders", "pos": [ 11, 20 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 185, 193 ] }
x-ray investigation of foot soft tissues and measurement of foot soft tissue thickness ( fstt ) , clinical examination and determination of the level of plasma sth were performed in 43 previously untreated patients with acromegaly and in 9 patients in clinical remission .
nichd_parent_of
{ "id": "C0220825", "name": "investigation", "pos": [ 6, 19 ] }
{ "id": "C0031809", "name": "clinical examination", "pos": [ 98, 118 ] }
this article provides a review of several quantitative tests and measures used to evaluate range of motion , edema , muscle performance , sensation , dexterity , and physical capacity .
nichd_parent_of
{ "id": "C0220825", "name": "evaluate", "pos": [ 82, 90 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 166, 174 ] }
gallium-67 citrate scanning has proved a sensitive test not only for pneumocystis carinii pneumonia but for many of the other opportunistic infections and malignancies , including mycobacterial infections and lymphoma .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 155, 167 ] }
{ "id": "C0024299", "name": "lymphoma", "pos": [ 209, 217 ] }
a rupture of the rotator cuff is demonstrated by arthrography of the shoulder joint , a diagnostic method that we think is necessary despite regular examinations with ultrasonography .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic", "pos": [ 88, 98 ] }
{ "id": "C0041618", "name": "ultrasonography", "pos": [ 167, 182 ] }
in most of the rheumatic diseases , disease activity can be reduced to a minimum using the smallest possible dose of drugs with known behaviors in pregnancy and lactation and thus providing minimal risk to mother and fetus .
nichd_parent_of
{ "id": "C0004927", "name": "behaviors", "pos": [ 134, 143 ] }
{ "id": "C0006147", "name": "lactation", "pos": [ 161, 170 ] }
the animals with antibodies binding strongly to the 3b peptide had an early htlv-iiib-induced cell-fusion-inhibiting ( cfi ) antibody response , while the animals with antibodies binding strongly to the 3b/rf peptide had a late htlv-iiib-induced cfi antibody response .
nichd_parent_of
{ "id": "C0003241", "name": "antibodies", "pos": [ 17, 27 ] }
{ "id": "C0035448", "name": "rf", "pos": [ 206, 208 ] }
based on the antibody profiles of nonapeptide recognition , peptides lav-1 , rf and sf2 were clustered , as were ny5 and cdc4 , and so were z6 , mal and eli .
nichd_parent_of
{ "id": "C0003241", "name": "antibody", "pos": [ 13, 21 ] }
{ "id": "C0035448", "name": "rf", "pos": [ 77, 79 ] }
however , antiviral chemotherapy is hindered by several obstacles : ( 1 ) most antiviral drugs are cytotoxic , with the exception of acyclovir which owes its remarkable safety to its activation by the thymidine kinase of the herpes simplex viruses and of the varicella-zoster virus ;
nichd_parent_of
{ "id": "C0042776", "name": "viruses", "pos": [ 240, 247 ] }
{ "id": "C0042338", "name": "varicella-zoster virus", "pos": [ 259, 281 ] }
the purpose of this study was to investigate interleukin 2 ( il-2 ) and gamma interferon ( ifn-gamma ) production by purified cd4+ and cd8+ cells isolated from peripheral blood ( pb ) and synovial fluid ( sf ) of patients with rheumatoid arthritis ( ra ) and other inflammatory arthritides ( non-ra ) .
nichd_parent_of
{ "id": "C0003864", "name": "inflammatory arthritides", "pos": [ 265, 289 ] }
{ "id": "C0003873", "name": "ra", "pos": [ 296, 298 ] }
41 lactating pakistani women were vaccinated orally with salmonella typhi vaccine alone or in combination with parenteral vibrio cholerae whole cell vaccine , in order to study the possible difference in the secretory response after live and inactivated vaccines .
nichd_parent_of
{ "id": "C0042210", "name": "vaccine", "pos": [ 74, 81 ] }
{ "id": "C0042212", "name": "inactivated vaccines", "pos": [ 242, 262 ] }
four children had alt elevation in consecutive blood samples , 2 of whom had a longlasting alt elevation , probably due to mother-to-infant transmission of nanbh virus ( es ) .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 5, 13 ] }
{ "id": "C0021270", "name": "infant", "pos": [ 133, 139 ] }
the value of c-reactive protein as a marker of bacterial infection in patients with septicaemia/endocarditis and influenza .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial infection", "pos": [ 47, 66 ] }
{ "id": "C0036690", "name": "septicaemia", "pos": [ 84, 95 ] }
in order to evaluate the capacity of c-reactive protein ( crp ) , erythrocyte sedimentation rate ( esr ) , white blood cell count ( wbc ) and polymorphonuclear neutrophils ( pmns ) to differentiate between bacterial and viral infection we studied 176 patients with septicaemia/endocarditis ( se ) , 59 patients with unco...
nichd_parent_of
{ "id": "C0042769", "name": "viral infection", "pos": [ 220, 235 ] }
{ "id": "C0021400", "name": "influenza", "pos": [ 380, 389 ] }
this disorder or syndrome is characterized by pain and tenderness over the gerdy 's tubercle and by aggravation of this pain on flexion and extension of the knee .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 5, 13 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 17, 25 ] }
the authors refer to the significance of the routine x-ray diagnosis and of the ct for finding a diagnosis with thorotrastosis .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 87, 94 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 97, 106 ] }
during the december outbreak 187 persons were affected , among them 90 % of children , through the consumption of imported oranges and tangerines , simultaneous infection with y. enterocolitica , serovars 05.27 and 09 , and hepatitis a virus being observed .
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 33, 40 ] }
{ "id": "C0008059", "name": "children", "pos": [ 76, 84 ] }
of the 17 diploid patients who died of disease , there were 11 tumors with high spf ( greater than 4.45 % ) and 6 tumors with a low spf ( p less than 0.05 chi-square test ) .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 39, 46 ] }
{ "id": "C0027651", "name": "tumors", "pos": [ 114, 120 ] }
in a group of 46 adult patients with acquired immunodeficiency syndrome ( aids ) who came to autopsy in 1983-1987 , the authors found that 38 ( 83 % ) had bacterial ( nonmycobacterial ) infections some time during the course of their illness , compared with 34 ( 74 % ) who had parasitic infections , 31 ( 67 % ) who had...
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 186, 196 ] }
{ "id": "C0747256", "name": "parasitic infections", "pos": [ 278, 298 ] }
in a group of 46 adult patients with acquired immunodeficiency syndrome ( aids ) who came to autopsy in 1983-1987 , the authors found that 38 ( 83 % ) had bacterial ( nonmycobacterial ) infections some time during the course of their illness , compared with 34 ( 74 % ) who had parasitic infections , 31 ( 67 % ) who had...
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 186, 196 ] }
{ "id": "C0042769", "name": "viral", "pos": [ 321, 326 ] }
in a group of 46 adult patients with acquired immunodeficiency syndrome ( aids ) who came to autopsy in 1983-1987 , the authors found that 38 ( 83 % ) had bacterial ( nonmycobacterial ) infections some time during the course of their illness , compared with 34 ( 74 % ) who had parasitic infections , 31 ( 67 % ) who had...
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 186, 196 ] }
{ "id": "C0026946", "name": "fungal infections", "pos": [ 360, 377 ] }
overall , undiagnosed infections or malignancies were found in 48 % , 22 of the 46 autopsies , including 12 cases of undiagnosed bacterial infections , 8 of these due to s. aureus .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 22, 32 ] }
{ "id": "C0004623", "name": "bacterial infections", "pos": [ 129, 149 ] }
however , anaerobic organisms were noted as a major group of pathogens and represented 27 % of our patients .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 20, 29 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 61, 70 ] }
conclusion : in the context of current clinical management strategies for suspected fungal infection , the candida antigen detection assay ( cand-tec ) is not a reliable method for diagnosis of deep candidiasis in neutropenic patients .
nichd_parent_of
{ "id": "C0026946", "name": "fungal infection", "pos": [ 84, 100 ] }
{ "id": "C0006840", "name": "candidiasis", "pos": [ 199, 210 ] }
in 11 cases with an abnormal outcome of pregnancy ( fetal death , fetal distress necessitating a cesarean section , or neonatal weight below the 10th percentile ) placental growth retardation always preceded fetal complications or growth retardation by at least 3 weeks .
nichd_parent_of
{ "id": "C0032972", "name": "outcome of pregnancy", "pos": [ 29, 49 ] }
{ "id": "C0015927", "name": "fetal", "pos": [ 208, 213 ] }
in 11 cases with an abnormal outcome of pregnancy ( fetal death , fetal distress necessitating a cesarean section , or neonatal weight below the 10th percentile ) placental growth retardation always preceded fetal complications or growth retardation by at least 3 weeks .
nichd_parent_of
{ "id": "C0032972", "name": "outcome of pregnancy", "pos": [ 29, 49 ] }
{ "id": "C0007876", "name": "cesarean section", "pos": [ 97, 113 ] }
fluids and blood products transfused , and preoperative ascites or icu care , were not related to blood cys levels .
nichd_parent_of
{ "id": "C0005889", "name": "fluids", "pos": [ 0, 6 ] }
{ "id": "C0456388", "name": "blood", "pos": [ 98, 103 ] }
after the 8 min , recovery was more rapid in children than in infants and adults up to and including the 15th min .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 45, 53 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 62, 69 ] }
tof ratio was greater in children ( 0.96 +/- 0.03 ) than in either adults ( 0.82 +/- 0.17 ) or in infants ( 0.83 +/- 0.14 ) ( p less than 0.05 ) .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 25, 33 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 98, 105 ] }
although tumors are often characterized as being the result of uncontrolled proliferation , clinically the morbidity from cancer results from its ability to invade and metastasize and to become resistance to our current therapeutic modalities such as chemotherapy and radiation .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 9, 15 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 122, 128 ] }
since self-reports of physiological states in patients with anxiety disorder are frequently unreliable , we compared 20 female patients with generalized anxiety disorder with a matched group of nonanxious controls on a battery of psychophysiological assessments ( skin conductance , heart interbeat interval , blood pres...
nichd_parent_of
{ "id": "C0003469", "name": "anxiety disorder", "pos": [ 60, 76 ] }
{ "id": "C0270549", "name": "generalized anxiety disorder", "pos": [ 141, 169 ] }
sixteen patients have been successfully decannulated , 11 remain cannulated and 1 died at home from sudden infant death syndrome .
nichd_parent_of
{ "id": "C0011065", "name": "died", "pos": [ 82, 86 ] }
{ "id": "C0038644", "name": "sudden infant death syndrome", "pos": [ 100, 128 ] }
the mechanism by which atherosclerotic plaque causes stroke and transient ischemic attack is not fully understood .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 53, 59 ] }
{ "id": "C0007787", "name": "transient", "pos": [ 64, 73 ] }
data were collected on 49 infants who died from sids in the dunedin and invercargill health districts of southern new zealand .
nichd_parent_of
{ "id": "C0011065", "name": "died", "pos": [ 38, 42 ] }
{ "id": "C0038644", "name": "sids", "pos": [ 48, 52 ] }
a total of 94 cases of fifth day fits occurred during this period , accounting for 57 % of all neonatal convulsions occurring during 1972-79 .
nichd_parent_of
{ "id": "C0036572", "name": "fits", "pos": [ 33, 37 ] }
{ "id": "C0159020", "name": "neonatal convulsions", "pos": [ 95, 115 ] }
the cognitive development at 2 and 5 years of a cohort of extremely low birthweight ( elbw ) children ( birthweight 500-999 g ) was compared with that of cohorts of larger very low birthweight ( vlbw ) children ( birthweight 1000-1500 g ) and normal birthweight ( nbw ) children ( birthweight greater than 2500 g ) to de...
nichd_parent_of
{ "id": "C0005612", "name": "birthweight", "pos": [ 72, 83 ] }
{ "id": "C0456065", "name": "elbw infants", "pos": [ 378, 390 ] }
- typical factorial diseases in fur bearing animals and rabbits are : the infectious coryza ( pasteurella multocida , bordetella bronchiseptica ) in rabbits , the coli-dysentery and the enterotoxemia in rabbits and herbivorous fur animals , the ascending infections of urinary tract , particular in young male minks , an...
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 20, 28 ] }
{ "id": "C0009450", "name": "infectious", "pos": [ 74, 84 ] }
- typical factorial diseases in fur bearing animals and rabbits are : the infectious coryza ( pasteurella multocida , bordetella bronchiseptica ) in rabbits , the coli-dysentery and the enterotoxemia in rabbits and herbivorous fur animals , the ascending infections of urinary tract , particular in young male minks , an...
nichd_parent_of
{ "id": "C0009450", "name": "infectious", "pos": [ 74, 84 ] }
{ "id": "C0009443", "name": "coryza", "pos": [ 85, 91 ] }
a reproductive health approach recognizes that the foundations of women 's health are laid in childhood and adolescence , and are influenced by factors such as nutrition , education , sexual roles and social status , cultural practices , and the socioeconomic environment .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 94, 103 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 108, 119 ] }
numerically , lung cancer accounted for most of the metastases seen , but the increase was made up by other tumours than lung cancer . especially malignant melanoma , mesothelioma , breast cancer and sarcomas .
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 19, 25 ] }
{ "id": "C1261473", "name": "sarcomas", "pos": [ 200, 208 ] }
the finding that l26 may give surface labelling in occasional tcls ( particularly of the pleomorphic , medium and large cell type ) indistinguishable from that seen in b cell lymphomas emphasises the importance of always using diagnostic mabs in combination if the risk of misinterpretation of lymphoma cell lineage is t...
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 4, 11 ] }
{ "id": "C0011900", "name": "diagnostic", "pos": [ 227, 237 ] }
an unusually high prevalence ( 45 % ) of serum antibodies to human t cell leukemia virus type i ( or to an antigenically related virus ) in comparison with that observed against other viral pathogens ( human immunodeficiency virus type 1 , herpes simplex virus , human cytomegalovirus , varicella zoster virus , and resp...
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 83, 88 ] }
{ "id": "C0042338", "name": "varicella zoster virus", "pos": [ 287, 309 ] }
the mean plasma clearance of morphine was significantly higher in children than neonates ( 25.7 and 4.7 ml min-1 kg-1 , respectively ) ( p less than 0.01 ) .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 66, 74 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 80, 88 ] }
all the children and five neonates had detectable concentrations of morphine-6-glucuronide ( m6g ) in plasma or urine .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 8, 16 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 26, 34 ] }
the m3g/morphine ratios in plasma and urine , and m6g/morphine ratios in urine were significantly higher in children than neonates ( p less than 0.01 ) , suggesting that morphine glucuronidation capacity is enhanced after the neonatal period .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 108, 116 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 122, 130 ] }
there was no difference in the m3g/m6g ratio in children and neonates , indicating a parallel development of both glucuronidation pathways .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 48, 56 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 61, 69 ] }
we conclude that the intranasal route does not allow rapid absorption of the drug and is not associated with greater bioavailability than the oral route .
nichd_parent_of
{ "id": "C0013153", "name": "route", "pos": [ 32, 37 ] }
{ "id": "C1527415", "name": "oral route", "pos": [ 142, 152 ] }
concentrations of inhibin in fluids entering and leaving the epididymis also were determined in a radioimmunoassay using the same antibody .
nichd_parent_of
{ "id": "C0005889", "name": "fluids", "pos": [ 29, 35 ] }
{ "id": "C0003241", "name": "antibody", "pos": [ 130, 138 ] }
however , the list of neurological manifestations described includes pseudotumour cerebri , hemiparesis , demyelinating disorders , optic atrophy , recurrent laryngeal nerve palsy and purulent meningitis so that lyme disease must now be considered in the differential diagnosis of a wide range of neurological disorders ...
nichd_parent_of
{ "id": "C0012634", "name": "disorders", "pos": [ 120, 129 ] }
{ "id": "C0027765", "name": "neurological disorders", "pos": [ 297, 319 ] }
unlike most bacterial infections , where diagnosis is by identification of the causal organism , diagnosis of infection by borrelia burgdorferi ( lyme 's borreliosis ) relies mostly upon indirect techniques .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 22, 31 ] }
{ "id": "C0024198", "name": "lyme 's", "pos": [ 146, 153 ] }
the occurrence of the neoplasm at an advanced stage in closely related individuals early in life suggests that underlying genetic factors may predispose to this malignancy .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasm", "pos": [ 22, 30 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 161, 171 ] }
the disease has run a benign course and there is no evidence of infection with human immunodeficiency virus ( hiv ) .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 4, 11 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 64, 73 ] }
the exact place of this disorder within the nosology of the cutaneous dermatoses is not yet fully established .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 24, 32 ] }
{ "id": "C0037274", "name": "dermatoses", "pos": [ 70, 80 ] }
both organisms are opportunistic pathogens with a predilection for patients with foreign bodies in place .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 5, 14 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 33, 42 ] }
infections included intraabdominal ( 42 cases ) , respiratory tract ( 52 cases ) , skin and soft tissue ( 29 cases ) , urinary tract ( 16 cases ) , and miscellaneous infections ( 14 cases ) that included typhoid fever , gastroenteritis , septicemia , and surgical wound infection .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 0, 10 ] }
{ "id": "C0038941", "name": "surgical wound", "pos": [ 255, 269 ] }
parenterally administered antibiotics are also required to decrease the incidence of local bacterial infection or septicemia .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial infection", "pos": [ 91, 110 ] }
{ "id": "C0036690", "name": "septicemia", "pos": [ 114, 124 ] }
nineteen patients were examined , only 4 of whom showed clinical signs of spastic weakness or ataxia .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 56, 70 ] }
{ "id": "C3714552", "name": "weakness", "pos": [ 82, 90 ] }