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it is the lymphohematogenic way of infection spreading that prevails in children with orbital complications of sinusitis .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 35, 44 ] }
{ "id": "C0037199", "name": "sinusitis", "pos": [ 111, 120 ] }
ointments and oils can be overgrown only by highly specialized organisms but if there is condensed water as a film at boundary surfaces much more microorganism species can grow .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 63, 72 ] }
{ "id": "C0445623", "name": "microorganism", "pos": [ 146, 159 ] }
of special interest is the finding that discrete symptoms such as venous congestion and slight pain appeared early in the course of the disease in all patients , and that in some of the patients an increase in intraocular pressure as well as disturbances in ocular motility were diagnosed long before the appearance of t...
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 27, 34 ] }
{ "id": "C0011900", "name": "diagnosed", "pos": [ 279, 288 ] }
seven of the responder eyes had capsular glaucoma undergoing treatment , six had simple glaucoma , two had pigmentary glaucoma and two suspicion of open-angle glaucoma .
nichd_parent_of
{ "id": "C0017601", "name": "glaucoma", "pos": [ 41, 49 ] }
{ "id": "C0017612", "name": "open-angle glaucoma", "pos": [ 148, 167 ] }
a simple , modified procedure for the dextrostix-eyetone system has been evaluated in order to enable the system to measure the concentration of glucose in serum as well as in whole blood .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 20, 29 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 73, 82 ] }
this combination of endocrine tumours and hyperplasias does not fit with the two multiple endocrine adenomatosis syndromes recognized at present .
nichd_parent_of
{ "id": "C0014132", "name": "endocrine tumours", "pos": [ 20, 37 ] }
{ "id": "C0027662", "name": "multiple endocrine adenomatosis", "pos": [ 81, 112 ] }
assuming that valve replacement is to be carried out in a large medical center by a surgical team experienced in this procedure , the results of this operation today are dependent more on the type and size of substitute valve inserted than on the surgeon who inserts the valve .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 118, 127 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 150, 159 ] }
a commerical adaptation of trinder 's glucose oxidase procedure for glucose determination was evaluated by regression analysis .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 54, 63 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 94, 103 ] }
this paper reviews recent ophthalmological manuscripts pertaining to wasting retinal nerve fibers , retinopathy related to systemic lymphomas , hypertensive retinopathy , diabetic retinopathy , retinal oxalosis , macular and foveal anomalies , retinal pigment epithelium , retinitis pigmentosa , retinoblastoma , histopl...
nichd_parent_of
{ "id": "C0035309", "name": "retinopathy", "pos": [ 100, 111 ] }
{ "id": "C0011884", "name": "diabetic retinopathy", "pos": [ 171, 191 ] }
the incidence of offenses against persons was 50 % in this sample , compared to 2 -- 3 % in the population of children referred to the juvenile court .
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 34, 41 ] }
{ "id": "C0008059", "name": "children", "pos": [ 110, 118 ] }
an analysis is provided of how this individual space capsule functions under varying circumstances , such as depression , schizophrenia , sociopathy , divorce , child-battery , aging , death , overpopulation , cultural disruption , and execution .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 36, 46 ] }
{ "id": "C0008059", "name": "child", "pos": [ 161, 166 ] }
the only way to solve the problem among future old people was to protect infants , children , and youths from becoming infected and remain so throughout life .
nichd_parent_of
{ "id": "C0027361", "name": "people", "pos": [ 51, 57 ] }
{ "id": "C0008059", "name": "children", "pos": [ 83, 91 ] }
bronchospasm can usually be attributed to cardiac disease if physical and roentgenographic examination support the diagnosis of cardiac failure .
nichd_parent_of
{ "id": "C0018799", "name": "cardiac disease", "pos": [ 42, 57 ] }
{ "id": "C0018801", "name": "cardiac failure", "pos": [ 128, 143 ] }
variations in the c3 and c4 fractions of complement were studied in 15 patients who underwent surgery with either spinal anesthesia ( 5 cases ) or general anesthesia using nitruos oxyde and a halogen compound ( 10 cases ) .
nichd_parent_of
{ "id": "C0002903", "name": "anesthesia", "pos": [ 121, 131 ] }
{ "id": "C0002915", "name": "general", "pos": [ 147, 154 ] }
the incidence of clinical signs considered to be specific for halothane-induced hepatitis ( skin rash , arthralgia , bronchospasm , fever of unexplained origin , leukocytosis ) was the same in both groups .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 17, 31 ] }
{ "id": "C0015230", "name": "skin rash", "pos": [ 92, 101 ] }
the incidence of clinical signs considered to be specific for halothane-induced hepatitis ( skin rash , arthralgia , bronchospasm , fever of unexplained origin , leukocytosis ) was the same in both groups .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 17, 31 ] }
{ "id": "C0003862", "name": "arthralgia", "pos": [ 104, 114 ] }
in this paper are considered the etiology , the clinical findings and the management of anaesthesia for a certain number of ent emergencies , situations of respiratory distress which may lead rapidly to death , or be the cause of severe complications , e.g .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 48, 65 ] }
{ "id": "C0009566", "name": "complications", "pos": [ 237, 250 ] }
in this study , when more than 6 organisms per high power field were found , the patient 's sputum or gastric material yielded a pathogenic mycobacterium on culture .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 33, 42 ] }
{ "id": "C0450254", "name": "pathogenic", "pos": [ 129, 139 ] }
a reo-like virus ( calf rotavirus ) was shown to be associated with cases of neonatal calf diarrhea in france .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 11, 16 ] }
{ "id": "C0035870", "name": "rotavirus", "pos": [ 24, 33 ] }
in adult hens ( gallus domesticus ) infusion into the iiird cerebral ventricle of 5,6-dht ( 50 , 75 and 100 mug ) produced , after 5-10 min behavioural and electrocortical sedation and sleep lasting about 6-8 hr , and a monophasic or biphasic increase in body temperature for about 8 hr , two and a half hr after 5,6-dht...
nichd_parent_of
{ "id": "C0004927", "name": "behavioural", "pos": [ 140, 151 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 185, 190 ] }
[ diseases of the anterior motor neuron , of preference appearance in childhood ( w.h . ) and in adolescence ( w.-k.-w. ) electroclinical relations ] .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 70, 79 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 97, 108 ] }
a severe nephropathy occurred , rapidly resulting in renal failure with histologic lesions of membrano-proliferative glomerulonephritis .
nichd_parent_of
{ "id": "C0022658", "name": "nephropathy", "pos": [ 9, 20 ] }
{ "id": "C0035078", "name": "renal failure", "pos": [ 53, 66 ] }
the soldiers with postcombat violence more frequently than the nonviolent had a history of fighting in childhood or adolescence , of volunteering for vietnam , of reporting thay they had killed four or more persons , and of reenlisting for additional tours of duty in vietnam .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 103, 112 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 116, 127 ] }
while nearly half of the patients had cardiac disease detected preoperatively , the elective group demonstrated a low incidence of previous myocardial infarction ( 7 % ) and congestive heart failure ( 8 % ) .
nichd_parent_of
{ "id": "C0018799", "name": "cardiac disease", "pos": [ 38, 53 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 140, 161 ] }
while nearly half of the patients had cardiac disease detected preoperatively , the elective group demonstrated a low incidence of previous myocardial infarction ( 7 % ) and congestive heart failure ( 8 % ) .
nichd_parent_of
{ "id": "C0018799", "name": "cardiac disease", "pos": [ 38, 53 ] }
{ "id": "C0018802", "name": "congestive heart failure", "pos": [ 174, 198 ] }
[ comparison between the epileptic manifestation of the lennox-gastaut syndrome with and without previous west syndrome ] .
nichd_parent_of
{ "id": "C0014544", "name": "epileptic", "pos": [ 25, 34 ] }
{ "id": "C0037769", "name": "west syndrome", "pos": [ 106, 119 ] }
then , the hypothesis that the disease is a multicausal syndrome appears , which by an identical physiopathologic process produces or exhibits a similar clinical , radiological and cisternographic picture .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 31, 38 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 56, 64 ] }
this procedure can be employed to evaluate central assumptions of biofeedback relating to posttraining awareness of changes in muscle tension and the relationship between awareness and control of muscle tension .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 5, 14 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 34, 42 ] }
it was concluded that the esr had little place in the management of syphilis in general , but could be helpful in the post-treatment follow-up of late syphilis .
nichd_parent_of
{ "id": "C0039128", "name": "syphilis", "pos": [ 68, 76 ] }
{ "id": "C0153188", "name": "late syphilis", "pos": [ 146, 159 ] }
if a male patient with shigellosis is homosexual , he should be screened for other sexually transmitted diseases such as syphilis , gonorrhoea , hepatitis b , and amoebiasis .
nichd_parent_of
{ "id": "C0036916", "name": "sexually transmitted diseases", "pos": [ 83, 112 ] }
{ "id": "C0039128", "name": "syphilis", "pos": [ 121, 129 ] }
if a male patient with shigellosis is homosexual , he should be screened for other sexually transmitted diseases such as syphilis , gonorrhoea , hepatitis b , and amoebiasis .
nichd_parent_of
{ "id": "C0036916", "name": "sexually transmitted diseases", "pos": [ 83, 112 ] }
{ "id": "C0018081", "name": "gonorrhoea", "pos": [ 132, 142 ] }
the tumor , derived from surface epidermis , was composed of masses of pale-staining benign-appearing prickle cells , deeply invaginated by thick , compact , partially parakeratotic horn .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 4, 9 ] }
{ "id": "C0577559", "name": "masses", "pos": [ 61, 67 ] }
the clinical presentation of the disease was either gastrointestinal , with chronic diarrhea and malabsorption , or neoplastic , with tumors frequently associated with either obstructive or perforative complications .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 33, 40 ] }
{ "id": "C0027651", "name": "tumors", "pos": [ 134, 140 ] }
a gas-liquid chromatography ( glc ) procedure for the detection of l-ornithine and l-lysine decarboxylase ( ec 4.1.1.17 and ec 4.1.1.18 , respectively ) activities of bacteria was developed and evaluated against moller 's method , a conventional biochemical test .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 36, 45 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 194, 203 ] }
[ points which enlighten the high mortality rate in the county of finnmark . can the high mortality rate today be a consequence of bad conditions of life in childhood and adolescence ? ] .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 157, 166 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 171, 182 ] }
in response to the november 1972 ruling of the california supreme court requiring complete , detailed disclosure of risks for procedures and treatments , a survey was made of the reactions of one hundred patients to this decision .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 126, 136 ] }
{ "id": "C0087111", "name": "treatments", "pos": [ 141, 151 ] }
five cases are described in which fear of the possibly hazardous effects of giving amphotericin to patients with kidney disease resulted in death from progressive infection by an amphotericin-sensitive fungus ( cryptococcus neoformans in three cases , blastomyces dermatitidis in one case , and histoplasma capsulatum in...
nichd_parent_of
{ "id": "C0026946", "name": "infection", "pos": [ 163, 172 ] }
{ "id": "C0010414", "name": "cryptococcus", "pos": [ 211, 223 ] }
but these organisms can be detected by immunofluorescence in 1-week-old mice , well in advance of the time the fusiform-shaped bacteria can be found .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 10, 19 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 127, 135 ] }
the concentrations of the individual amino acids was increased to 1.7-4.2 times those normally present in foetal plasma , and the final values reached were similar to the concentrations of free amino acid found in placental tissue.4 .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 26, 36 ] }
{ "id": "C0015965", "name": "foetal", "pos": [ 106, 112 ] }
[ diagnostic significance of the segmental perfusion methods , fat balance and indirect jejunal function tests ( author 's transl ) ] .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic", "pos": [ 2, 12 ] }
{ "id": "C0022885", "name": "tests", "pos": [ 105, 110 ] }
[ changes in body temperature and metabolism in children and infants during ether and halothane anesthesia . ii . variation of the skin temperature ] .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 48, 56 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 61, 68 ] }
during serial distension of the rectum , 64 per cent of patients with solitary rectal ulcer , 75 per cent with anterior mucosal prolapse and 76 per cent with rectal prolapse , but only 10 per cent of controls , showed repetitive rectal contractions .
nichd_parent_of
{ "id": "C0033377", "name": "prolapse", "pos": [ 128, 136 ] }
{ "id": "C0034888", "name": "rectal prolapse", "pos": [ 158, 173 ] }
the results indicated that three behavioural techniques ( listening to tv/radio/stereo , sleeping , talking about pain ) and one cognitive technique ( thinking about something else ) were rated as effective by the majority of subjects for average levels of pain .
nichd_parent_of
{ "id": "C0004927", "name": "behavioural", "pos": [ 33, 44 ] }
{ "id": "C0037313", "name": "sleeping", "pos": [ 89, 97 ] }
comparison of their sequences with those of ribosomal proteins from other organisms revealed that proteins s14 , s16 , s19 , and l25 are related to both eukaryotic and eubacterial ribosomal proteins , being more homologous to eukaryotic than eubacterial counterparts , and proteins s12 , s15 , and l16 are related to onl...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 74, 83 ] }
{ "id": "C0004611", "name": "eubacterial", "pos": [ 242, 253 ] }
previously stated characteristic differences between the eubacterial and eukaryotic molecules , namely , the length base-pairing schemes of helices d , can be used as a marker for the various archaebacterial branches .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 18, 32 ] }
{ "id": "C1444754", "name": "length", "pos": [ 109, 115 ] }
a large cell malignancy identified as a b-lymphoma only by virtue of mu and kappa chain gene rearrangement additionally displayed profuse plasmalemma marking with anti-epithelial membrane antigen ( ema ) .
nichd_parent_of
{ "id": "C0006826", "name": "malignancy", "pos": [ 13, 23 ] }
{ "id": "C0024299", "name": "lymphoma", "pos": [ 42, 50 ] }
the mean tumor volume doubling time of these 15 nodules was 102 +/- 77 days ( mean +/- sd ; range 41 to 305 days ) before the initiation of a specific treatment for cancer .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 9, 14 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 165, 171 ] }
there have been two locoregional recurrences in a mean follow-up period of 33 months ( range , 12 to 54 months ) in patients evaluated by physical examination , carcinoembryonic antigen ( cea ) levels , computed axial tomography ( cat ) scans , endoscopy , and reoperation or autopsy ( p = 0.01 ) .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 125, 134 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 138, 158 ] }
currently , the most important roles of transport theory include using approximate solutions of the transport equation as theoretical foundations of dose computation algorithms , and using monte carlo simulation to calculate basic treatment planning data , characteristic of the treatment modality , which can serve as i...
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 257, 271 ] }
{ "id": "C0695347", "name": "modality", "pos": [ 289, 297 ] }
tumor , cancer-prone , and normal human cells , which represent a wide range of cells with varied repair capacities , were investigated to better understand the role of xips in dna damage responses .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 0, 5 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 8, 14 ] }
these technical approaches revealed that 17 beta-estradiol and prolactin stimulated the thymidine labeling index of both hi ( despite the lack of detectable estrogen receptors ) and hs mxt tumors whereas progesterone influenced only that of hs cancers .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 189, 195 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 244, 251 ] }
while further studies are needed to document that biochemical modulation can be achieved in the target tumor in humans , this study supports the development of clinical trials using streptozotocin as a biochemical modulator of nitrosourea resistance in human malignancies .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 103, 108 ] }
{ "id": "C0006826", "name": "malignancies", "pos": [ 259, 271 ] }
a total of 19 patients with different cancers , including seven large-bowel carcinomas , three chronic myelogenous leukemias , three hypernephromas , two small-cell lung cancers , one malignant melanoma , one malignant lymphoma , one rhabdomyosarcoma and one fibrosarcoma were treated .
nichd_parent_of
{ "id": "C0006826", "name": "cancers", "pos": [ 38, 45 ] }
{ "id": "C0024299", "name": "malignant lymphoma", "pos": [ 209, 227 ] }
in the group monitored during administration of chemotherapeutic drugs we observed 5-8 hours after administration of cytostatics serious ventricular arrhythmias [ incl . ventricular tachycardia ] , denivelization of the st segment , paroxysms of supraventricular tachycardia .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 137, 160 ] }
{ "id": "C0042514", "name": "ventricular", "pos": [ 251, 262 ] }
fifty-one osteoarthritic knees evaluated by arthroscopic , roentgenographic , and clinical examinations prior to high tibial valgus osteotomy were reevaluated roentgenographically and clinically after a minimum follow-up period of five years ( average , 6.2 years ; range , 5-8.3 years ) .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 31, 40 ] }
{ "id": "C0031809", "name": "clinical examinations", "pos": [ 82, 103 ] }
certain other medical and behavioral conditions need to receive careful consideration prior to finalizing the diagnosis of attention deficit hyperactivity disorder ( adhd ) .
nichd_parent_of
{ "id": "C0004930", "name": "behavioral conditions", "pos": [ 26, 47 ] }
{ "id": "C1263846", "name": "attention deficit", "pos": [ 123, 140 ] }
although calcium antagonists are drugs which have been introduced relatively recently , their use is already so widespread , at least in the treatment of cardiovascular diseases as to represent one of the main therapies for diseases such as ischaemic cardiopathy , arterial hypertension , and , to a lesser extent , arrh...
nichd_parent_of
{ "id": "C0007222", "name": "the", "pos": [ 88, 91 ] }
{ "id": "C0020538", "name": "arterial hypertension", "pos": [ 265, 286 ] }
among patients with postoperative congenital heart disease , a few are totally cured and require no special follow-up or any special precautions , e.g. , those with certain cases of atrial septal defect of ostium secundum types , patent ductus arteriosus without pulmonary hypertension , and fully repaired total anomaly...
nichd_parent_of
{ "id": "C0152021", "name": "congenital heart disease", "pos": [ 34, 58 ] }
{ "id": "C0013274", "name": "patent ductus", "pos": [ 230, 243 ] }
lower pulmonary tract cell populations collected by bronchoalveolar lavages ( bal ) were evaluated in three groups of immunocompromised patients : hiv infected patients with pneumocystis carinii ( pc ) pneumonitis ( n = 22 ) , or pneumonitis not related to pc ( n = 29 ) , and non-hiv-infected , immunocompromised patien...
nichd_parent_of
{ "id": "C0032285", "name": "pneumonitis", "pos": [ 202, 213 ] }
{ "id": "C1535939", "name": "pc pneumonitis", "pos": [ 330, 344 ] }
both of these organisms appeared to have initially grown as spheroplasts , but revertant bacteria were cultivated after transfer into fresh media .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 14, 23 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 89, 97 ] }
of 108 malignancies , 101 were correctly sampled ( sensitivity , 93.5 % ) , including 30 primary hepatocellular carcinomas , 70 metastatic tumors , and 1 lymphoma .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 7, 19 ] }
{ "id": "C0024299", "name": "lymphoma", "pos": [ 154, 162 ] }
a 43 year old woman with no previous skin disease developed contact eczema on the face and neck after application of a lotion used for `` '' smoothing wrinkels '' '' , available as a non-prescription item .
nichd_parent_of
{ "id": "C0037274", "name": "skin disease", "pos": [ 37, 49 ] }
{ "id": "C0011616", "name": "contact eczema", "pos": [ 60, 74 ] }
however , if the tumour diameter is greater than 6 cm , an adrenalectomy is indicated because of the danger of malignancy .
nichd_parent_of
{ "id": "C0027651", "name": "tumour", "pos": [ 17, 23 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 111, 121 ] }
to check these criteria a step-by-step diagnostic procedure was instituted which consisted of history , ultrasonography with contractility test , abdominal x-ray film , computed tomography measurement of stone density , and endoscopic retrograde cholangiography .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic procedure", "pos": [ 39, 59 ] }
{ "id": "C0041618", "name": "ultrasonography", "pos": [ 104, 119 ] }
to check these criteria a step-by-step diagnostic procedure was instituted which consisted of history , ultrasonography with contractility test , abdominal x-ray film , computed tomography measurement of stone density , and endoscopic retrograde cholangiography .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic procedure", "pos": [ 39, 59 ] }
{ "id": "C0022885", "name": "test", "pos": [ 139, 143 ] }
most of these tumors occur in the oral cavity , and there is a much higher incidence of malignancy than is the case with the major salivary glands .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 14, 20 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 88, 98 ] }
an analysis of seizure counts in the 12-week treatment period with ltg showed a statistically significant reduction in seizures as compared with placebo for total seizures ( p less than 0.002 ) , partial seizures ( p less than 0.002 ) , and secondarily generalized seizures ( p less than 0.05 ) .
nichd_parent_of
{ "id": "C0036572", "name": "seizures", "pos": [ 119, 127 ] }
{ "id": "C0751495", "name": "partial seizures", "pos": [ 196, 212 ] }
these procedures allow the investigation of activity changes of single neurons and of cell ensembles using statistical methods .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 6, 16 ] }
{ "id": "C0220825", "name": "investigation", "pos": [ 27, 40 ] }
comparison of the p. carinii sequence to corresponding sequences of organisms from other taxa showed the p. carinii sequence to be more similar to sequences from the fungi ( saccharomyces cerevisiae , neurospora crassa , candida albicans , and cryptococcus diffuens ) than to protozoan sequences .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 68, 77 ] }
{ "id": "C0016832", "name": "fungi", "pos": [ 166, 171 ] }
in aids group iv patients ( cdc classification ) anaemia ( 92 % ) neutropenia ( 85 % ) monocytopenia ( 75 % ) and thrombocytopenia ( 61 % ) have their highest incidence , the reason being a combination of factors such as infection , myelosuppressive drugs and hiv infection itself .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 221, 230 ] }
{ "id": "C0019693", "name": "hiv infection", "pos": [ 260, 273 ] }
atenolol significantly reduced atrial arrhythmias and had a good effect on exercise-induced arrhythmias ( reduced in 75 % of patients ) , but it did not have a significant effect on ventricular arrhythmias .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmias", "pos": [ 38, 49 ] }
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 182, 205 ] }
peripheral neuropathy is a common and well-studied complication of diabetes mellitus , but the possibility that central neuropathy is also present has received scant attention .
nichd_parent_of
{ "id": "C0031117", "name": "peripheral neuropathy", "pos": [ 0, 21 ] }
{ "id": "C0442874", "name": "neuropathy", "pos": [ 120, 130 ] }
observations of a small lymphocytic infiltrate arising in the region of a gastric ulcer that lacked definitive morphologic evidence of malignancy ( lymphoma ) but was clearly a monoclonal b-cell proliferation by immunohistochemical and gene rearrangement studies support the notion that some gastric lymphoproliferative ...
nichd_parent_of
{ "id": "C0006826", "name": "malignancy", "pos": [ 135, 145 ] }
{ "id": "C0024299", "name": "lymphoma", "pos": [ 371, 379 ] }
ki-67 seems to be an important immunohistochemical marker of breast cancer , which contributes to the individual assessment of the disease and can possibly give predictions on tumor development and response to radiation and systemic therapy .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 131, 138 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 176, 181 ] }
these findings suggest that patients in primary care settings may have depressive symptoms severe enough to provoke tricyclic therapy or referral but do not meet current diagnostic criteria .
nichd_parent_of
{ "id": "C0087111", "name": "therapy", "pos": [ 126, 133 ] }
{ "id": "C0034927", "name": "referral", "pos": [ 137, 145 ] }
the population of noise-exposed regions has higher rates and more distinct forms of disorders in myocardium , vessel elasticity , hemodynamics , extracardial regulation and higher risk of cardiovascular disease than those living under more quiet conditions .
nichd_parent_of
{ "id": "C0012634", "name": "disorders", "pos": [ 84, 93 ] }
{ "id": "C0007222", "name": "cardiovascular disease", "pos": [ 188, 210 ] }
from this study it would seem unjustifiable to perform this procedure on all patients undergoing evaluation for exenteration .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 60, 69 ] }
{ "id": "C0220825", "name": "evaluation", "pos": [ 97, 107 ] }
quantitative and qualitative examinations of serum lipoproteins separated by use of discontinuous ultracentrifugation were performed in 17 lactating and 13 non-lactating healthy women 5 days and 5 weeks after delivery .
nichd_parent_of
{ "id": "C0205556", "name": "qualitative", "pos": [ 17, 28 ] }
{ "id": "C0018684", "name": "healthy", "pos": [ 170, 177 ] }
yet the short duration of c.r . suggests the opportunity of performing consolidation cycles or suprelethal therapy followed by bone marrow transplantation .
nichd_parent_of
{ "id": "C0087111", "name": "therapy", "pos": [ 107, 114 ] }
{ "id": "C0005961", "name": "bone marrow transplantation", "pos": [ 127, 154 ] }
the peripheral nerve diseases are present as distal symmetric sensomotory neuropathy , as chronic demyelinating polyradiculoneuropathy , as acute polyradiculoneuritis and as mononeuropathy multiplex .
nichd_parent_of
{ "id": "C0031117", "name": "peripheral nerve diseases", "pos": [ 4, 29 ] }
{ "id": "C0442874", "name": "neuropathy", "pos": [ 178, 188 ] }
at the present time , it is not clear whether this disorder is a new syndrome that is different from acute pandysautonomia or merely a subtype of it .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 51, 59 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 69, 77 ] }
while consensus has been reached for some organs and tumors that dna quantitation by flow cytometry ( or image cytometry ) may be of prognostic value , for most cancers studied to date the information remains incomplete .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 53, 59 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 161, 168 ] }
finally , we can obtain a preferable set of diagnostic tests for given symptoms/signs by using the join of sd and dt , and for further diagnosis , the join of dd and dt is applicable .
nichd_parent_of
{ "id": "C0037088", "name": "symptoms/signs", "pos": [ 71, 85 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 135, 144 ] }
protein malnutrition did not exacerbate disease in the reinfected group beyond that observed in malnourished animals infected with the hv isolate only , but neither did the infection with the lvsr isolate protect the lp animals against reinfection with the hv isolate .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 40, 47 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 238, 247 ] }
a substance capable of increasing histamine production by bone marrow cells was found in the pouch fluid of allergic rats , while it was absent in the normal rat serum and pouch fluid of nonsensitized rats .
nichd_parent_of
{ "id": "C0439861", "name": "substance", "pos": [ 2, 11 ] }
{ "id": "C0005889", "name": "fluid", "pos": [ 178, 183 ] }
neurological abnormalities diagnosed before death were associated with sids , but much of the association was removed by adjusting for birthweight .
nichd_parent_of
{ "id": "C0011065", "name": "death", "pos": [ 44, 49 ] }
{ "id": "C0038644", "name": "sids", "pos": [ 71, 75 ] }
the optical characteristics of the developing chick lens , including paraxial and eccentric focal lengths , were measured during the embryonic period of development and up to 15 days after hatching .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 12, 27 ] }
{ "id": "C1444754", "name": "lengths", "pos": [ 98, 105 ] }
a dog with a myeloproliferative disorder and thrombocytosis had clinical signs that were consistent with a diagnosis of essential thrombocythemia .
nichd_parent_of
{ "id": "C0836924", "name": "thrombocytosis", "pos": [ 45, 59 ] }
{ "id": "C0040028", "name": "essential thrombocythemia", "pos": [ 120, 145 ] }
in order of frequency , the following clinical signs were reported : coughing , dyspnea , occasional sneezing , wheezing , and vomiting .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 38, 52 ] }
{ "id": "C0010200", "name": "coughing", "pos": [ 69, 77 ] }
in order of frequency , the following clinical signs were reported : coughing , dyspnea , occasional sneezing , wheezing , and vomiting .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 38, 52 ] }
{ "id": "C0013404", "name": "dyspnea", "pos": [ 80, 87 ] }
in order of frequency , the following clinical signs were reported : coughing , dyspnea , occasional sneezing , wheezing , and vomiting .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 38, 52 ] }
{ "id": "C0037383", "name": "sneezing", "pos": [ 101, 109 ] }
in order of frequency , the following clinical signs were reported : coughing , dyspnea , occasional sneezing , wheezing , and vomiting .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 38, 52 ] }
{ "id": "C0043144", "name": "wheezing", "pos": [ 112, 120 ] }
in order of frequency , the following clinical signs were reported : coughing , dyspnea , occasional sneezing , wheezing , and vomiting .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 38, 52 ] }
{ "id": "C0042963", "name": "vomiting", "pos": [ 127, 135 ] }
this is in direct contrast to a pathologic renal condition , polycystic kidney disease , in which the level of protooncogene expression is out of proportion to the degree of cell proliferation .
nichd_parent_of
{ "id": "C0022658", "name": "renal condition", "pos": [ 43, 58 ] }
{ "id": "C0022680", "name": "polycystic kidney disease", "pos": [ 61, 86 ] }
these results confirm the role of psychological variables in the experience of clinical pain and underscore the highly affective nature of chronic pain .
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 88, 92 ] }
{ "id": "C0150055", "name": "chronic pain", "pos": [ 139, 151 ] }
the exact role of preoperative or palliative renal embolization is still controversial , but if the procedure is performed , the natural course of the neoplasm can be best evaluated and followed by serial ct scans .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 100, 109 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 172, 181 ] }
most recently , we have been able to induce this disease in man with the aim of investigating its therapeutic effect in autologous bmt in patients with ia-bearing tumors .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 49, 56 ] }
{ "id": "C0027651", "name": "tumors", "pos": [ 163, 169 ] }
ninety fetal doppler echocardiographic examinations were performed on 72 normal fetuses and 5 with congenital heart disease [ 2 pulmonary stenosis ( ps ) , 1 pulmonary atresia ( pa ) , 1 tetralogy of fallot ( tof ) and 1 endocardial cushion defect ( ecd ) ] at 16 to 40 weeks of gestational age .
nichd_parent_of
{ "id": "C0152021", "name": "congenital heart disease", "pos": [ 99, 123 ] }
{ "id": "C0242855", "name": "pulmonary atresia", "pos": [ 158, 175 ] }
ninety fetal doppler echocardiographic examinations were performed on 72 normal fetuses and 5 with congenital heart disease [ 2 pulmonary stenosis ( ps ) , 1 pulmonary atresia ( pa ) , 1 tetralogy of fallot ( tof ) and 1 endocardial cushion defect ( ecd ) ] at 16 to 40 weeks of gestational age .
nichd_parent_of
{ "id": "C0152021", "name": "congenital heart disease", "pos": [ 99, 123 ] }
{ "id": "C0039685", "name": "tetralogy of fallot", "pos": [ 187, 206 ] }
intervention : a preliminary evaluation included physical examination , routine laboratory tests , dietary assessment , and psychiatric evaluation .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 29, 39 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 49, 69 ] }