text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
the most constant clinical sign associated with hydrops fetalis was polyhydramnios which is an indication for ultrasonography and cardiotocography to detect cases of nihf and to select the optimum time for delivery . | nichd_parent_of | {
"id": "C0020305",
"name": "hydrops fetalis",
"pos": [
48,
63
]
} | {
"id": "C0455988",
"name": "nihf",
"pos": [
166,
170
]
} |
( 1 ) the characteristics of the temperature dependence of the activity - the slopes and inflection temperature , ti , of the arrhenius plots - have been shown to depend on the total concentration , but not on the specific properties of added monovalent ions . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
10,
25
]
} | {
"id": "C0039476",
"name": "temperature",
"pos": [
100,
111
]
} |
several methods for the analysis of occupational radiation exposure data , including procedures based on cox 's proportional hazards model , are presented and evaluated . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
85,
95
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
159,
168
]
} |
the system presents the following characteristics : simple and rapid procedure , reproducibility , sensitivity ( urokinase levels down to 1 ng/ml ) and evaluation of the enzyme in biological fluids such as urine , pleural effusions , and ascitic fluids without preliminary purification . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
69,
78
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
152,
162
]
} |
less than half of patients with carcinomatous lymphadenopathy had symptoms and these tended to be organ specific , whereas three-quarters of patients with lymphoma had symptoms which were usually non-specific . | nichd_parent_of | {
"id": "C0006826",
"name": "carcinomatous",
"pos": [
32,
45
]
} | {
"id": "C0024299",
"name": "lymphoma",
"pos": [
155,
163
]
} |
although penicillin is the drug of choice in syphilis , treatment failures with benzathine and procaine penicillin have occurred in neurosyphilis . | nichd_parent_of | {
"id": "C0039128",
"name": "syphilis",
"pos": [
45,
53
]
} | {
"id": "C0027927",
"name": "neurosyphilis",
"pos": [
132,
145
]
} |
those rats fed a wheat bran supplement during carcinogen administration and then switched to a fiber-free diet afterwards had the highest tumor yield , 4.5 times as many benign and malignant tumors as in those rats consistently fed the fiber-free diet ( p less than 0.05 ) and at least 6 times as many adenomas as any of... | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
138,
143
]
} | {
"id": "C0006826",
"name": "malignant tumors",
"pos": [
181,
197
]
} |
in addition , a considerable quantitative variation in expression of this surface antigen was demonstrated among the cells of each population in both normal and neoplastic breast cells which spread over an 8- to 10-fold range . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
29,
41
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
220,
225
]
} |
we report here that 1,25- ( oh ) 2d3 had a biphasic effect on the replication of two distinct human cancer cell lines , i.e. , the breast cancer t-47d and the malignant melanoma mm96 , an effect analogous to that of estrogens on the breast cancer cell line mcf-7 . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
100,
106
]
} | {
"id": "C0025202",
"name": "malignant melanoma",
"pos": [
159,
177
]
} |
eleven cases of lymphoblastic malignancy , presenting as lymphoma , were investigated for immunological and differentiation markers prior to the onset of therapy . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
30,
40
]
} | {
"id": "C0024299",
"name": "lymphoma",
"pos": [
57,
65
]
} |
more detailed attention was also paid to the persons committing the crime , to motives which made them commit the crime and the subsequent fate of the children . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
"pos": [
45,
52
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
151,
159
]
} |
clinical efficacy of the assay was demonstrated in children with renal disorders , especially those associated with chronic renal failure or tubular dysfunction . | nichd_parent_of | {
"id": "C0022658",
"name": "renal disorders",
"pos": [
65,
80
]
} | {
"id": "C0022661",
"name": "chronic renal failure",
"pos": [
116,
137
]
} |
in a patient with clinical features of niemann-pick disease type c , the finding of such a profile would thus be a good argument for the diagnosis , but it is not pathognomonic as we found similar changes in two cases with gm1-gangliosidosis , while some cases of niemann-pick disease type c have borderline normal profi... | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
73,
80
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
137,
146
]
} |
the rate of pre-eclampsia in second pregnancy is less than in first pregnancy , but this is altered by the outcome of the first pregnancy with reference to length of gestation , occurrence of pre-eclampsia and abortion . | nichd_parent_of | {
"id": "C0032972",
"name": "outcome of",
"pos": [
107,
117
]
} | {
"id": "C0156543",
"name": "abortion",
"pos": [
210,
218
]
} |
the second major t-lymphocyte subpopulation , which bears the leu-2/okt-8 antigen , was numerically normal in all the disease syndromes , but increased as a percentage of all circulating lymphocytes . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
118,
125
]
} | {
"id": "C0039082",
"name": "syndromes",
"pos": [
126,
135
]
} |
in contrast , the colon and breast cancer patients with stage iv disease possessed pmn cells which were more effective than normal cells in killing the tumor targets . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
65,
72
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
152,
157
]
} |
hypertension was most frequent and severe in membranoproliferative and sclerotic glomerulonephritis , but often mild and transient in extracapillary glomerulonephritis . | nichd_parent_of | {
"id": "C0017658",
"name": "glomerulonephritis",
"pos": [
81,
99
]
} | {
"id": "C0403416",
"name": "extracapillary glomerulonephritis",
"pos": [
134,
167
]
} |
this evolution seems to be faster in sickle-cell anaemia than in s/beta ( 0 ) -thalassaemia and sc disease . | nichd_parent_of | {
"id": "C0002895",
"name": "sickle-cell anaemia",
"pos": [
37,
56
]
} | {
"id": "C0019034",
"name": "sc disease",
"pos": [
96,
106
]
} |
in 3.5 % thyroiditis was diagnosed , 75 % struma lymphomatosa hashimoto and 25 % subacute thyroiditis de quervain . | nichd_parent_of | {
"id": "C0040147",
"name": "thyroiditis",
"pos": [
9,
20
]
} | {
"id": "C0040149",
"name": "thyroiditis de quervain",
"pos": [
90,
113
]
} |
on the basis of the registered finding the system provides full automated topographic or syndromological diagnosis . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
31,
38
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
105,
114
]
} |
multistage models of carcinogenesis proposed to account for the observed patterns of tumor development in the skin , liver , lung , bladder and other organs involve initiation of neoplastic change in a few cells by a threshold dose of carcinogen followed by conversion of these latent tumor cells into an autonomous canc... | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
85,
90
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
316,
322
]
} |
an examination of those studies where groups of people in regions of low and high lead contamination have been compared shows that the child/adult blood-lead ratio is almost always enhanced in the more exposed groups . | nichd_parent_of | {
"id": "C0027361",
"name": "people",
"pos": [
48,
54
]
} | {
"id": "C0008059",
"name": "child",
"pos": [
135,
140
]
} |
these and previous observations on other host tissues suggest that tumor-doubling time , which is a known factor in metastatic spread and survival , may also be a variable in the production of systemic agents through which neoplasms affect the metabolic state of the cancer host . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
223,
232
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
267,
273
]
} |
in one animal which received phenylbutazone , clinical signs of toxicity ( lethargy , inappetence , oedema ) were observed and evidence of hepatotoxicity and haematological changes were also noted in this horse . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical",
"pos": [
46,
54
]
} | {
"id": "C0023380",
"name": "lethargy",
"pos": [
75,
83
]
} |
in one animal which received phenylbutazone , clinical signs of toxicity ( lethargy , inappetence , oedema ) were observed and evidence of hepatotoxicity and haematological changes were also noted in this horse . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical",
"pos": [
46,
54
]
} | {
"id": "C0013604",
"name": "oedema",
"pos": [
100,
106
]
} |
no correlation was found between response to treatment with tamoxifen and disease free interval but a favourable connection was observed between good response and low grade of anaplasia of the tumor . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
74,
81
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
193,
198
]
} |
since they produce measurable tails of mucus in vitro , suspensions of urn cell complexes provide a bioassay for mucus-stimulating substances ( mss ) in biological fluids , including several human body fluids . | nichd_parent_of | {
"id": "C0439861",
"name": "substances",
"pos": [
131,
141
]
} | {
"id": "C0005889",
"name": "fluids",
"pos": [
202,
208
]
} |
these tumors were a medulloblastoma ( te-671 ) and a glioma ( u-251 ) with mass doubling times of 3.5 and 5.5 days respectively as subcutaneous implants in nude mice . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
6,
12
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
75,
79
]
} |
to evaluate the relationships between changes in muscle morphology and metabolic adaptation to physical training in obesity , twenty obese women were subjected to a physical training programme with three sessions a week for 3 months . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
"pos": [
3,
11
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
165,
173
]
} |
it is of interest that development of these tumors occurs during peak senescent changes in the thymus , supporting the view that as fish age , accompanied by atrophy of the thymus , the immune system is less vigorous and there is an increase in the incidence of cancer . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
44,
50
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
262,
268
]
} |
further studies conducted with agents that modify central and/or peripheral gaba-ergic systems could lead to the discovery of drugs that might be useful for treating certain cardiovascular disorders in man , such as hypertension and stroke , and should increase our understanding of the pathophysiological bases of such ... | nichd_parent_of | {
"id": "C0007222",
"name": "cardiovascular disorders",
"pos": [
174,
198
]
} | {
"id": "C0020538",
"name": "hypertension",
"pos": [
216,
228
]
} |
the conditions of the new-born babies who had received piracetam were superior to those of the babies treated with the placebo , as evaluated with the apgar at 1 , 5 and 10 minutes after birth and on the basis of the neurological and clinical examination as from 24 hours until they were released . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
132,
141
]
} | {
"id": "C0031809",
"name": "clinical examination",
"pos": [
234,
254
]
} |
all children entering the infants ward and showing no sign of gastrointestinal disorders were distributed at random into two groups . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
4,
12
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
26,
33
]
} |
recognizing that there is a need for an animal model for the study of viruses associated with human diarrhea , a preliminary investigation attempting to ascertain the susceptibility of the baboon ( papio cynocephalus ) to a rotavirus was undertaken . | nichd_parent_of | {
"id": "C0042776",
"name": "viruses",
"pos": [
70,
77
]
} | {
"id": "C0035870",
"name": "rotavirus",
"pos": [
224,
233
]
} |
one month following a single 5 x 10 ( 10 ) organism dose of texas star , 7 vaccinees and 6 controls were challenged with 10 ( 6 ) pathogenic el tor ogawa vibrios . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
43,
51
]
} | {
"id": "C0450254",
"name": "pathogenic",
"pos": [
130,
140
]
} |
twelve vaccinees who received two 10 ( 9 ) or two 2 x 10 ( 10 ) organisms doses of texas star 1 week apart were challenged with 10 ( 6 ) pathogenic v. cholerae el tor of the heterologous serotype . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
64,
73
]
} | {
"id": "C0450254",
"name": "pathogenic",
"pos": [
137,
147
]
} |
nine patients were evaluated during long term therapy by means of clinical examination , exercise testing , chest-x-ray and echocardiography . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
19,
28
]
} | {
"id": "C0031809",
"name": "clinical",
"pos": [
66,
74
]
} |
the association of glomerulonephritis and persistent hbs antigenemia is reported in 4 adults with nephrotic syndrome : 2 cases of membranous glomerulonephritis associated with chronic persistent hepatitis and 2 cases of membrano-proliferative glomerulonephritis associated with active cirrhosis . | nichd_parent_of | {
"id": "C0017658",
"name": "glomerulonephritis",
"pos": [
19,
37
]
} | {
"id": "C0017665",
"name": "membranous glomerulonephritis",
"pos": [
130,
159
]
} |
the procedure employed for surgical interruption of anomalous pathways is dependent on the localization of the accessory atrioventricular bundle . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
4,
13
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
27,
35
]
} |
to clarify salient issues pertaining to histiocytosis x -- a syndrome that includes letterer-siwe disease , hand-schuller-christian disease , and eosinophilic granuloma -- the authors review the epidemiologic data and the histologic , morphologic , and clinical bases for diagnosis and prognosis . | nichd_parent_of | {
"id": "C0019621",
"name": "hand-schuller-christian disease",
"pos": [
108,
139
]
} | {
"id": "C0014461",
"name": "eosinophilic granuloma",
"pos": [
146,
168
]
} |
the three best-known disorders which seem to be inherited in this way , are incontinentia pigmenti ( ip ) bloch-sulzberger , oral-facial-digital i ( ofd i ) syndrome , and focal dermal hypoplasia ( fdh syndrome , goltz syndrome ) . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
21,
30
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
219,
227
]
} |
these disorders are : x-linked chondrodysplasia punctata ( cp ) , cervico-oculo-acusticus syndrome ( wildervanck syndrome , coa ) , congenital cataract with microcornea or slight microphthalmia , muscular dystrophy -- hemizygous lethal , partial lipodystrophy with lipatrophic diabetes and hyperlipidemia , aicardi syndr... | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
6,
15
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
374,
382
]
} |
antigenically distinct rotaviruses , i.e. , viruses morphologically identical to conventional rotaviruses by electron microscopy , yet lacking the common group antigen ( s ) detected by an enzyme-linked immunosorbent assay , were found in 2 of 51 fecal samples from bulgarian infants with rotavirus gastroenteritis . | nichd_parent_of | {
"id": "C0042776",
"name": "viruses",
"pos": [
27,
34
]
} | {
"id": "C0035870",
"name": "rotaviruses",
"pos": [
94,
105
]
} |
the live oral vaccine gave significantly better protection than the heat-vaccinated , subcutaneously injected vaccine since ( i ) only control calves and calves given the killed vaccine developed profuse diarrhea , ( ii ) clinically , the mild fever responses seen after challenge in calves given the live vaccine were s... | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
14,
21
]
} | {
"id": "C0042211",
"name": "live vaccine",
"pos": [
475,
487
]
} |
the live oral vaccine gave significantly better protection than the heat-vaccinated , subcutaneously injected vaccine since ( i ) only control calves and calves given the killed vaccine developed profuse diarrhea , ( ii ) clinically , the mild fever responses seen after challenge in calves given the live vaccine were s... | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
14,
21
]
} | {
"id": "C0042212",
"name": "killed",
"pos": [
515,
521
]
} |
it was determined that the disease syndrome caused by the virus in this mouse strain is dependent upon the age of the animals . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
27,
34
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
35,
43
]
} |
logistic regression models revealed an unexpected interaction among light bleeding , hormone usage , and pregnancy outcome in that the risks of a low birth weight , pre-term and small-for-dates term delivery were significantly increased only for those women who had light bleeding and who had not used therapeutic hormon... | nichd_parent_of | {
"id": "C0032972",
"name": "pregnancy outcome",
"pos": [
105,
122
]
} | {
"id": "C0233324",
"name": "term",
"pos": [
194,
198
]
} |
tumors derived from surface epithelium , including brenner tumors , expressed prekeratin in the epithelial cells , whereas sex cord-stromal tumors showed only vimentin-type imf . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
0,
6
]
} | {
"id": "C0206724",
"name": "sex cord-stromal",
"pos": [
123,
139
]
} |
( 3 ) the basis for the aetiological diagnosis in the individual child , and ( 4 ) the value of non-audiological investigations . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
54,
64
]
} | {
"id": "C0008059",
"name": "child",
"pos": [
65,
70
]
} |
based on the present and previous investigations , a routine examination programme is proposed directed towards a systematic evaluation of the symptom of hearing loss and its aetiology with due caution to the individual child . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
209,
219
]
} | {
"id": "C0008059",
"name": "child",
"pos": [
220,
225
]
} |
to save the boy 's life an extensive operation was performed with total extirpation of the thyroid gland and the adjacent tissues , total laryngectomy and resection of the cervical trachea , combined with bilateral neck dissection . | nichd_parent_of | {
"id": "C0543467",
"name": "operation",
"pos": [
37,
46
]
} | {
"id": "C0015250",
"name": "total",
"pos": [
132,
137
]
} |
our surgical techniques for the complete removal of large tumours of the anterior skull base are described . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical techniques",
"pos": [
4,
23
]
} | {
"id": "C0015250",
"name": "complete removal",
"pos": [
32,
48
]
} |
tumor control and therapeutic gain with different schedules of combined radiotherapy and local external hyperthermia in human cancer . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
0,
5
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
126,
132
]
} |
the most frequent clinical signs included weight loss , polyphagia , increased activity , polydipsia , polyuria , and vomiting . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
18,
32
]
} | {
"id": "C0042963",
"name": "vomiting",
"pos": [
118,
126
]
} |
the procedure evaluates , in quantitative terms , the ability of media ( 1 ) to support the formation of colonies by organisms that it was designed to grow and ( 2 ) to resist colonization by organisms that it is expected to suppress . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
4,
13
]
} | {
"id": "C0220825",
"name": "evaluates",
"pos": [
14,
23
]
} |
around 60 % of curly-tail mice spontaneously develop neural tube defects ( ntd ) , that is , exencephaly , and/or spina bifida ( open lesions ) , or a curly tail ( closed lesion ) , due to an incompletely penetrant recessive gene . | nichd_parent_of | {
"id": "C0027794",
"name": "neural tube defects",
"pos": [
53,
72
]
} | {
"id": "C0080178",
"name": "spina bifida",
"pos": [
114,
126
]
} |
by using an antibody capture principle and f ( ab ' ) 2 conjugates , interference of rheumatoid factors was absent . | nichd_parent_of | {
"id": "C0003241",
"name": "antibody",
"pos": [
12,
20
]
} | {
"id": "C0035448",
"name": "rheumatoid factors",
"pos": [
85,
103
]
} |
these findings indicate the need both for further understanding of the nature of self-disclosure and also concurrent investigations of hypertensive characteristics and blood pressure responsivity . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
148,
163
]
} | {
"id": "C0005823",
"name": "blood pressure",
"pos": [
168,
182
]
} |
the 15-year prospective study of cardiovascular disease among a cohort of japanese men in hawaii provided an opportunity to examine the temporal trends of coronary heart disease ( chd ) incidence and mortality rates and to compare them with hawaii state chd mortality rates . | nichd_parent_of | {
"id": "C0007222",
"name": "the",
"pos": [
0,
3
]
} | {
"id": "C0018799",
"name": "the",
"pos": [
231,
234
]
} |
to evaluate the relationship between physical characteristics of the lips during vowel production and vowel lipreading confusions , four female talkers were videotaped producing 15 american english vowels and diphthongs in an /h/-v-/g/ context . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
"pos": [
3,
11
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
37,
45
]
} |
a printout of the entire electrocardiographic recording was made and hand counts of ventricular arrhythmias were correlated with heart rate , qtc interval , rr interval preceding ventricular fibrillation or torsade de pointes and ( rr ' ) /qt initiating ventricular fibrillation or torsade de pointes . | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
84,
107
]
} | {
"id": "C0042510",
"name": "ventricular fibrillation",
"pos": [
254,
278
]
} |
common ambulatory electrocardiographic features in these 12 patients experiencing ventricular fibrillation or torsade de pointes included : 1 ) a period of high density of increasingly frequent or complex ventricular arrhythmias , or both , preceding ventricular fibrillation or torsade de pointes ( 11 patients ) ; | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
205,
228
]
} | {
"id": "C0042510",
"name": "ventricular fibrillation",
"pos": [
251,
275
]
} |
a procedure employing simple otoscopy in 785 ears gave an 83 per cent agreement , but in about 15 per cent of these ears the examiner felt unable to base his evaluation on certainty . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
2,
11
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
158,
168
]
} |
a vasodilatation induced by an anaesthesia of the sympathetic chain or by a general anaesthesia by penthotal produces a raising of the whole curve above the basic line . | nichd_parent_of | {
"id": "C0002903",
"name": "anaesthesia",
"pos": [
31,
42
]
} | {
"id": "C0002915",
"name": "general anaesthesia",
"pos": [
76,
95
]
} |
in addition , the data have a significant bearing on the pathogenesis of the pco syndrome and the development of hirsutism which may be directly related to the high androgen levels in pco women in whom the levels of lh are normally raised . | nichd_parent_of | {
"id": "C0039082",
"name": "syndrome",
"pos": [
81,
89
]
} | {
"id": "C0032460",
"name": "pco",
"pos": [
184,
187
]
} |
one hundred adult volunteers were administered inactivated vaccine ( 20 micrograms/0.5 cc ) intramuscularly ( im ) or intranasally ( in ) , or 10 ( 4.7 ) tcid50 of a live cold-adapted vaccine ( cr35 ) in . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
59,
66
]
} | {
"id": "C0042211",
"name": "live",
"pos": [
166,
170
]
} |
while improvements in headaches were observed in all groups , the best improvements took place in the thermal biofeedback group , which had almost complete elimination of migraine attacks by the end of training , and maintained that performance as long as six months after training . | nichd_parent_of | {
"id": "C0018681",
"name": "headaches",
"pos": [
22,
31
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
171,
179
]
} |
patients with distal fistula were examined separately as were the patients without a fistula and those with only a tracheoesophageal fistula . | nichd_parent_of | {
"id": "C0016169",
"name": "fistula",
"pos": [
21,
28
]
} | {
"id": "C0040588",
"name": "tracheoesophageal",
"pos": [
115,
132
]
} |
the molecular features for the best activities are a phenyl group in the c-6 position of the 3 ( 2h ) -pyridazinone ring , a four-atom chain length between the 3 ( 2h ) -pyridazinone ring and the 2-cyanoguanidine moiety , and a thioether rather than an ether linkage . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
14,
22
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
141,
147
]
} |
until recently our evaluation of impotent men included a psychiatric evaluation , and history and physical examination by a urologist to determine whether the impotence was organic or psychogenic . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluation",
"pos": [
19,
29
]
} | {
"id": "C0031809",
"name": "physical examination",
"pos": [
98,
118
]
} |
mcr is considered to be a useful antibiotic in the treatment of various infectious diseases combined with underlying diseases , such as progressive cancer and leukemia , and the infectious diseases of the aged . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
83,
91
]
} | {
"id": "C0009450",
"name": "infectious diseases",
"pos": [
178,
197
]
} |
during the disease-free interval , 37 % ( 10/27 ) of er ( + ) tumors changed to er ( - ) , and all er ( - ) tumors remained negative . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
11,
18
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
108,
114
]
} |
nephroblastomas of low risk ( congenital mesoblastic nephroma , fetal rhabdomyomatous nephroblastoma , cystic partially differentiated nephroblastoma ) - in most of these cases simple nephrectomy sufficient as adequate therapy . | nichd_parent_of | {
"id": "C0027708",
"name": "nephroblastoma",
"pos": [
0,
14
]
} | {
"id": "C1266139",
"name": "cystic partially differentiated nephroblastoma",
"pos": [
103,
149
]
} |
the following data was obtained by morphometric and photometric microscopic studies of renal biopsies from 140 patients with idiopathic perimembranous glomerulonephritis , 108 patients with focally sclerosing glomerulonephritis and 50 patients with membranoproliferative glomerulonephritis and correlation of the results... | nichd_parent_of | {
"id": "C0017658",
"name": "glomerulonephritis",
"pos": [
151,
169
]
} | {
"id": "C0017662",
"name": "membranoproliferative glomerulonephritis",
"pos": [
249,
289
]
} |
in ocular mg , low titres and an infrequent finding of antibodies to achr ( 32 % ) as well as the low prevalence of associated autoantibodies and ai diseases indicate that this subgroup of mg consists of patients with restricted ai reactivity . | nichd_parent_of | {
"id": "C0004364",
"name": "ai diseases",
"pos": [
146,
157
]
} | {
"id": "C0026896",
"name": "mg",
"pos": [
189,
191
]
} |
the burn areas covered with these allogeneic cultured epidermal allografts were tangentially excised deep second-degree burns which routinely would have been covered with split-thickness autografts . | nichd_parent_of | {
"id": "C0006434",
"name": "burn",
"pos": [
4,
8
]
} | {
"id": "C0332687",
"name": "second-degree burns",
"pos": [
106,
125
]
} |
a study of the distribution of metronidazole in the blood and tissues after its administration shows that the best route of its administration is a combined one ( 1/3 of the dose per os and 2/3 with the enema ) . | nichd_parent_of | {
"id": "C0013153",
"name": "route of",
"pos": [
115,
123
]
} | {
"id": "C1527415",
"name": "per os",
"pos": [
179,
185
]
} |
at all 13 sites exposed to high energy density ( j2t = 1.60-7.50 ) , the maximum skin temperatures beneath the electrodes were 55-81 degrees c , and severe burns were produced with white to brownish , dry , firm , third-degree burns surrounded by peripheral rings of second-degree burns . | nichd_parent_of | {
"id": "C0006434",
"name": "burns",
"pos": [
156,
161
]
} | {
"id": "C0332687",
"name": "second-degree burns",
"pos": [
267,
286
]
} |
analysis regarding individual viruses showed significantly higher titers to cmv and rub in cord blood , a higher titer to vzv in maternal blood , and similar levels of antibodies to ebv , hsv-1 , and adv in maternal and cord blood . | nichd_parent_of | {
"id": "C0042776",
"name": "viruses",
"pos": [
30,
37
]
} | {
"id": "C0042338",
"name": "vzv",
"pos": [
122,
125
]
} |
by means of the immunoprecipitation method significantly higher activities of creatine kinase bb isoenzyme were measured in the sera of neonates with cns symptoms than in the sera of healthy or sick neonates without cns symptoms . | nichd_parent_of | {
"id": "C0021289",
"name": "neonates",
"pos": [
136,
144
]
} | {
"id": "C2825562",
"name": "sick neonates",
"pos": [
194,
207
]
} |
the tendency towards metabolic acidosis developing during simple infections lead to the detection of hyperglycinemia which was shown to be caused by the rare inborn error of metabolism , which was shown to be a methylmalonic acidemia , in identical twins . | nichd_parent_of | {
"id": "C0025521",
"name": "inborn error of metabolism",
"pos": [
158,
184
]
} | {
"id": "C0268583",
"name": "methylmalonic acidemia",
"pos": [
211,
233
]
} |
low platelet counts in patients who have immune thrombocytopenia according to clinical criteria but are resistant to therapy may be related to factors other than igg antibody . | nichd_parent_of | {
"id": "C0392386",
"name": "low platelet counts",
"pos": [
0,
19
]
} | {
"id": "C0272286",
"name": "immune thrombocytopenia",
"pos": [
41,
64
]
} |
renal angiograms revealed intraparenchymal arterial microaneuvrysms which led to the diagnosis of vasculitis of the periarteritis nodosa type . | nichd_parent_of | {
"id": "C0042384",
"name": "vasculitis",
"pos": [
98,
108
]
} | {
"id": "C0031036",
"name": "periarteritis nodosa",
"pos": [
116,
136
]
} |
the authors stress great difficulties in evaluating the combined action of toxic and physical factors on the nervous system . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluating",
"pos": [
41,
51
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
85,
93
]
} |
in the literature , arrest of hydrocephalus was noted in 50 per cent of 14 cases of obstructive hydrocephalus with spontaneous ventriculocisternostomy . | nichd_parent_of | {
"id": "C0020255",
"name": "hydrocephalus",
"pos": [
30,
43
]
} | {
"id": "C0549423",
"name": "obstructive hydrocephalus",
"pos": [
84,
109
]
} |
a technique for the diagnosis of bilateral cleft lip and palate before 20 weeks ' gestation with real-time ultrasound equipment is described and illustrated . | nichd_parent_of | {
"id": "C0430022",
"name": "technique",
"pos": [
2,
11
]
} | {
"id": "C0041618",
"name": "ultrasound",
"pos": [
107,
117
]
} |
we employed echotomography ( by 2.25-5mhz probes ) as a quick procedure to measure the vessel diameter at definite points to detect aneurysms and their evolution , to evaluate the arteriovenous fistula ( avf ) characteristics , to detect haematoma , thrombi , and collateral vessels . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
62,
71
]
} | {
"id": "C0220825",
"name": "evaluate",
"pos": [
167,
175
]
} |
this finding provides the second polymorphic marker for human chromosome 8 and , moreover , a molecular disease marker , because human ca ii deficiency has recently been linked to an autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
104,
111
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
203,
211
]
} |
sonographic features of these tumors include ( a ) dilatation of the intrahepatic biliary ducts but not the extrahepatic duct , ( b ) non-union of the right and left hepatic ducts , and ( c ) small , solid masses at the hepatic hilus . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
30,
36
]
} | {
"id": "C0240225",
"name": "masses",
"pos": [
206,
212
]
} |
[ cholesterol and the severity of coronary disease . its value in the prognosis following myocardial infarction ] . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
"pos": [
18,
21
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
90,
111
]
} |
where there was the co-existence of another disorder ( connective tissue disorders , sarcoid , extrinsic allergic alveolitis , radiation lung or diffuse interstitial fibrosis ) the anomalies noted were those occurring during the progress of the associated disease . | nichd_parent_of | {
"id": "C0012634",
"name": "disorder",
"pos": [
44,
52
]
} | {
"id": "C0009782",
"name": "connective tissue disorders",
"pos": [
55,
82
]
} |
increased severity of sleep apnea after 3 oz of 80-proof alcohol ingestion in patients with sleep apnea syndrome . | nichd_parent_of | {
"id": "C0003578",
"name": "apnea",
"pos": [
28,
33
]
} | {
"id": "C0037315",
"name": "sleep apnea syndrome",
"pos": [
92,
112
]
} |
encephalitis ( the definition of which should be reappraised ) occurred once in 2,850 cases , and subacute sclerosing panencephalitis was not rare ( incidence , one case per 2.6 million people ) . | nichd_parent_of | {
"id": "C0014038",
"name": "encephalitis",
"pos": [
0,
12
]
} | {
"id": "C0038522",
"name": "subacute sclerosing panencephalitis",
"pos": [
98,
133
]
} |
despite favorable trends in the control of measles in canada , the social and economic impacts of this disease remain substantial and warrant a nationwide effort to eliminate indigenous infection . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
103,
110
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
186,
195
]
} |
the agents of disease must be restricted to a single host species within which transmission occurs by relatively direct contact , and infection induces solid immunity . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
14,
21
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
134,
143
]
} |
on the other hand , a febrile reaction was observed in 20 % and 5 % , respectively , of children immunized with the aik-c vaccine or the further-attenuated schwarz vaccine , both of which were developed in japan . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
122,
129
]
} | {
"id": "C0042211",
"name": "attenuated",
"pos": [
145,
155
]
} |
an inexpensive nebulizer and the procedure for administration of aerosolized vaccine to individual children are here described . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
88,
98
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
99,
107
]
} |
mass immunization against measles in the czechoslovak socialist republic ( cssr ) began in 1969 and utilized the czechoslovak vaccine , which corresponds in its parameters to the further-attenuated measles vaccines . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
126,
133
]
} | {
"id": "C0042211",
"name": "attenuated",
"pos": [
187,
197
]
} |
metabolic and physiological processes play important roles in regulating the transfer and behavior of trace elements in the soil/plant/animal system . | nichd_parent_of | {
"id": "C0031845",
"name": "physiological processes",
"pos": [
14,
37
]
} | {
"id": "C0004927",
"name": "behavior",
"pos": [
90,
98
]
} |
oral administration of 13-cis-retinoic acid ( 40 or 160 milligrams per kilogram of body weight daily ) significantly reduced the inflammation associated with developing and established adjuvant arthritis , an experimentally induced arthritis in rats that resembles human rheumatoid arthritis . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
194,
203
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
271,
291
]
} |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.