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these findings may explain the painless nature of many of the clinical manifestations of syphilis as well as the severe damage to central nervous system tissue in tertiary and congenital syphilis .
nichd_parent_of
{ "id": "C0039128", "name": "syphilis", "pos": [ 89, 97 ] }
{ "id": "C0039131", "name": "congenital syphilis", "pos": [ 176, 195 ] }
formation of colonies in vitro occurred in 125 of 164 primary tumors ( 76 % ) , including 34 of 47 uroepithelial cancer specimens , 45 of 50 renal cell cancer specimens , 24 of 33 prostatic cancer specimens , and 22 of 34 testicular cancer specimens .
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 113, 119 ] }
{ "id": "C0007134", "name": "renal cell cancer", "pos": [ 141, 158 ] }
growth sufficient for chemosensitivity testing ranged from 43 % of the uroepithelial cancers cultured to 64 % of the renal cell cancer specimens cultured .
nichd_parent_of
{ "id": "C0006826", "name": "cancers", "pos": [ 85, 92 ] }
{ "id": "C0007134", "name": "renal cell cancer", "pos": [ 117, 134 ] }
an attention to details of the clinical picture , the age at presentation , the finding of diabetes insipidus , and the presence of calcification and intrasellar extension of the tumor , should help with the selection of the appropriate treatment technique and , thus , influence the probability of tumor control as well as of complications .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 80, 87 ] }
{ "id": "C0009566", "name": "complications", "pos": [ 327, 340 ] }
accounting for histopathologic diagnosis , stage of disease , ploidy , and the proportion of tumor g1/100 cells , the following sequence of adverse prognostic factors in order of their relative ranks was established : ( 1 ) absence of breast cancer ( p=0.0001 ) , ( 2 ) hypertriploid dna index ( p=0.049 ) , and ( 3 ) presence of metastatic disease ( p=0.079 ) .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 93, 98 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 242, 248 ] }
phase ii trial of spirogermanium in breast adenocarcinoma : a cancer and leukemia group b study .
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 62, 68 ] }
{ "id": "C0023418", "name": "group", "pos": [ 82, 87 ] }
the adaptations to the extremely high basal metabolism of these small mammals are reflected in the architectural characteristics of the hapatocytes , which , in comparison with those of the rat , show a smaller cell volume of the mononuclear hepatocytes ( 3,800 micrometers3 ) , and increased number of cells per cm3 of liver tissue ( 250 x 10 ( 6 ) ) , and a relative larger liver volume ( 4.85 ml per 100 g body weight ) .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 113, 128 ] }
{ "id": "C0005910", "name": "body weight", "pos": [ 409, 420 ] }
most of the 13 countries that participated in this ten-year study of the incidence of acute persisting spinal paralysis ( apsp ) used trivalent live poliomyelitis vaccine ( sabin strains ) , but monovalent vaccines were used for all or part of the time in 3 countries and inactivated vaccines were used wholly by 2 countries and in part by 2 other countries .
nichd_parent_of
{ "id": "C0042210", "name": "vaccines", "pos": [ 206, 214 ] }
{ "id": "C0042212", "name": "inactivated vaccines", "pos": [ 272, 292 ] }
the organism responsible for triggering the malakoplakia was corynebacterium hofmannii , and this is only the third report of this organism as a human pathogen .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 4, 12 ] }
{ "id": "C0450254", "name": "pathogen", "pos": [ 151, 159 ] }
aerosols play an important role in the treatment of various forms of respiratory disease , with bronchodilators for the therapy of asthma being particularly important .
nichd_parent_of
{ "id": "C0035204", "name": "respiratory disease", "pos": [ 69, 88 ] }
{ "id": "C0004096", "name": "asthma", "pos": [ 131, 137 ] }
in addition , during adolescence there is a greater increase in the incidence of skin disease is due to the occurrence of acne vulgaris in 249.9 per thousand youths in the 12 to 17-year old age range .
nichd_parent_of
{ "id": "C0037274", "name": "of", "pos": [ 78, 80 ] }
{ "id": "C0001144", "name": "acne vulgaris", "pos": [ 122, 135 ] }
other skin diseases that are extremely common in this age range include ( in decreasing frequency ) dermatophytosis , benign tumours , seborrhoeic dermatitis , atopic dermatitis and eczema , ichthyosis and keratosis pilaris , and verruca vulgaris .
nichd_parent_of
{ "id": "C0037274", "name": "skin diseases", "pos": [ 6, 19 ] }
{ "id": "C0036508", "name": "seborrhoeic dermatitis", "pos": [ 135, 157 ] }
other skin diseases that are extremely common in this age range include ( in decreasing frequency ) dermatophytosis , benign tumours , seborrhoeic dermatitis , atopic dermatitis and eczema , ichthyosis and keratosis pilaris , and verruca vulgaris .
nichd_parent_of
{ "id": "C0037274", "name": "skin diseases", "pos": [ 6, 19 ] }
{ "id": "C0013595", "name": "eczema", "pos": [ 182, 188 ] }
other skin diseases that are extremely common in this age range include ( in decreasing frequency ) dermatophytosis , benign tumours , seborrhoeic dermatitis , atopic dermatitis and eczema , ichthyosis and keratosis pilaris , and verruca vulgaris .
nichd_parent_of
{ "id": "C0037274", "name": "skin diseases", "pos": [ 6, 19 ] }
{ "id": "C0020757", "name": "ichthyosis", "pos": [ 191, 201 ] }
other skin diseases that are extremely common in this age range include ( in decreasing frequency ) dermatophytosis , benign tumours , seborrhoeic dermatitis , atopic dermatitis and eczema , ichthyosis and keratosis pilaris , and verruca vulgaris .
nichd_parent_of
{ "id": "C0037274", "name": "skin diseases", "pos": [ 6, 19 ] }
{ "id": "C0043037", "name": "verruca vulgaris", "pos": [ 230, 246 ] }
twenty patients with a variety of serious or difficult infections and 5 additional orthopaedic patients with clinical evidence of post-operative wound infection were treated with netilmicin .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 55, 65 ] }
{ "id": "C0038941", "name": "post-operative wound", "pos": [ 130, 150 ] }
the findings support the suggestion that subvalvular aneurysms , like aortic sinus aneurysms , are a result of a congenital defect at the valve anulus .
nichd_parent_of
{ "id": "C0002940", "name": "aneurysms", "pos": [ 53, 62 ] }
{ "id": "C0003486", "name": "aortic", "pos": [ 70, 76 ] }
clinical signs included anorexia in all cases , emaciation , fever , anaemia and/or palpable abdominal masses in 3 , colic in 2 and dysphagia in one case .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0003123", "name": "anorexia", "pos": [ 24, 32 ] }
clinical signs included anorexia in all cases , emaciation , fever , anaemia and/or palpable abdominal masses in 3 , colic in 2 and dysphagia in one case .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0015967", "name": "fever", "pos": [ 61, 66 ] }
the levels were lower in complicated pregnancies , namely threatened abortion , intra uterine fetal death , ectopic pregnancy , anencephalus and so on .
nichd_parent_of
{ "id": "C0032962", "name": "complicated pregnancies", "pos": [ 25, 48 ] }
{ "id": "C0000821", "name": "threatened abortion", "pos": [ 58, 77 ] }
some of these compounds have been considered as therapeutic agents for certain hemoglobinopathies such as sickle-cell disease .
nichd_parent_of
{ "id": "C0019045", "name": "hemoglobinopathies", "pos": [ 79, 97 ] }
{ "id": "C0002895", "name": "sickle-cell disease", "pos": [ 106, 125 ] }
data were recorded on their pregnancy outcomes ( normal , abortion , stillbirth and congenital malformation ) , as well as on their interpregnancy intervals .
nichd_parent_of
{ "id": "C0032972", "name": "pregnancy outcomes", "pos": [ 28, 46 ] }
{ "id": "C0156543", "name": "abortion", "pos": [ 58, 66 ] }
among the patients with cerebral palsy it was found that the attributes likely to define a wheelchair-user were spastic quadriplegia , functional level iii and iv , seizures and severe sensory handicap ;
nichd_parent_of
{ "id": "C0007789", "name": "cerebral palsy", "pos": [ 24, 38 ] }
{ "id": "C0426970", "name": "spastic", "pos": [ 112, 119 ] }
birth weight with low birth weights women had more rarely a good relationship to the infant in the early days post-partum .
nichd_parent_of
{ "id": "C0005612", "name": "birth weight", "pos": [ 0, 12 ] }
{ "id": "C0024032", "name": "birth", "pos": [ 22, 27 ] }
in only 20 % of women with children under 3000 grams the early relationship was good compared to a good relationship in 61 % with infants over 3500 grams birth weights .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 27, 35 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 130, 137 ] }
in individual cases -- such as during pregnancy or where the patient still desires to have children -- the ca . in situ with not free margins , can be treated simply with a secondary coagulation of the wound crater .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 3, 13 ] }
{ "id": "C0008059", "name": "children", "pos": [ 91, 99 ] }
the possibilities of a coincidence of diseases , a postsplenectomy reaction or a genuine myeloproliferative syndrome as the cause underlying a secondary disease are discussed .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 38, 46 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 108, 116 ] }
risk children have somewhat higher values than newborns , the difference , however , being statistically not significant .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 5, 13 ] }
{ "id": "C0021289", "name": "newborns", "pos": [ 47, 55 ] }
all these organisms are very rarely found in birds due to the fact that the blood smears made from peripheral blood of birds are unsuitable for the diagnosis of these parasites .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 10, 19 ] }
{ "id": "C0030498", "name": "parasites", "pos": [ 167, 176 ] }
sonography of the breast is gaining in importance with the spread of diagnostic methods based on ultrasound in general and the increasing technical perfection of the equipment in particular .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic", "pos": [ 69, 79 ] }
{ "id": "C0041618", "name": "ultrasound", "pos": [ 97, 107 ] }
the best techniques for this diagnosis are endoscopic retrograde cholangiopancreatography , abdominal ultrasonography and computerized tomography .
nichd_parent_of
{ "id": "C0430022", "name": "techniques", "pos": [ 9, 19 ] }
{ "id": "C0041618", "name": "ultrasonography", "pos": [ 102, 117 ] }
these results and the observations made on the cutaneous fibrous histiocytomas , atypical fibroxanthomas , dermatofibrosarcoma protuberans , and the various soft tissue sarcomas indicated that 1 ) alpha 1-antitrypsin is a valuable marker of histiocytic differentiation in both benign and malignant fibrous histiocytomas , 2 ) ferritin can be visualized in more than half of these fibroblastic-histiocytic tumors , and the presence of ferritin distinguishes the spindle cells of these tumors from fibroblasts of connective tissue and most fibrosarcomas , and 3 ) lysozyme , although a good marker of histiocytic differentiation in ordinary histiocytes and benign fibrous histiocytomas , is a poor marker of neoplastic histiocytes of malignant tumors .
nichd_parent_of
{ "id": "C1261473", "name": "soft tissue sarcomas", "pos": [ 157, 177 ] }
{ "id": "C0016057", "name": "fibrosarcomas", "pos": [ 538, 551 ] }
the pharmacokinetics of netilmicin were analyzed in 30 children , including 13 premature and seven gestationally mature newborns .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 55, 63 ] }
{ "id": "C0021289", "name": "newborns", "pos": [ 120, 128 ] }
although the infection can be transmitted from person to person , it is mainly a zoonosis with many possible routes of infection .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 13, 22 ] }
{ "id": "C0043528", "name": "zoonosis", "pos": [ 81, 89 ] }
repeated intramuscular or subcutaneous injections of polyvinylpyrrolidone over a long time can lead to tumor-like foreign body reactions mimicking true malignant tumors by clinical and histological features .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 103, 108 ] }
{ "id": "C0006826", "name": "malignant tumors", "pos": [ 152, 168 ] }
these factors are then derived for women , children and infants by scaling the dimensions of the male lung .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 43, 51 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 56, 63 ] }
five of seven patients receiving miso alone developed peripheral neuropathies while only one out of 7 patients that received miso with dxm coverage developed a transient and mild neuropathy .
nichd_parent_of
{ "id": "C0031117", "name": "peripheral neuropathies", "pos": [ 54, 77 ] }
{ "id": "C0442874", "name": "neuropathy", "pos": [ 179, 189 ] }
organisms that contained these compounds included the single example of a eucaryotic alga , a euglena , and a cyanobacterium ( blue-green alga ) , 22 of 32 genera of bacteria , and 9 genera of yeasts .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 0, 9 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 166, 174 ] }
detailed quantitative comparison with theoretical distributions over a wide range of actin concentrations , however , indicated that the pathway which catalyzed atp hydrolysis with a low extent of exchange only made a significant contribution at a low actin concentration and did not represent a major fraction of the total hydrolysis seen at higher actin concentrations .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 9, 21 ] }
{ "id": "C1514721", "name": "range", "pos": [ 76, 81 ] }
it encodes a preproenzyme of 246 amino acids comprising a hydrophobic prepeptide ( signal peptide ) of 15 amino acids , an activation peptide characteristic of trypsinogens , and an active form of trypsin , 223 amino acids in length , that has 78 % amino acid sequence identity with porcine trypsin .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 142, 156 ] }
{ "id": "C1444754", "name": "length", "pos": [ 226, 232 ] }
preferences for attachment agents and the reinforcing efficacy of their individual components were assessed in 100 pre-school-aged children .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 72, 82 ] }
{ "id": "C0008059", "name": "children", "pos": [ 131, 139 ] }
these observations suggest that : 1 ) endogenous opiate mechanisms are unlikely to constitute a principal factor in maintaining hypogonadotropism in idiopathic hypopituitarism , delayed adolescence , or kallmann 's syndrome , at least acutely ;
nichd_parent_of
{ "id": "C0020619", "name": "hypogonadotropism", "pos": [ 128, 145 ] }
{ "id": "C0162809", "name": "kallmann 's syndrome", "pos": [ 203, 223 ] }
the results of this study indicate that sows immune to rotavirus can shed virus in their feces at a time when piglets are particularly susceptible to infection and that adult swine are of primary importance in the epidemiology of rotavirus as initiators of infection .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 59, 64 ] }
{ "id": "C0035870", "name": "rotavirus", "pos": [ 230, 239 ] }
the api 20s streptococcus identification system and a new immunorheophoresis procedure were evaluated as means for determining the lancefield serogroup of beta-hemolytic streptococci recovered from human clinical specimens .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 77, 86 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 92, 101 ] }
low reliability and shortcomings in bip validation studies suggest that the diagnostic validity of the bip is lower than previously reported .
nichd_parent_of
{ "id": "C0184661", "name": "bip", "pos": [ 36, 39 ] }
{ "id": "C0430022", "name": "diagnostic", "pos": [ 76, 86 ] }
carpal tunnel syndrome in cutaneous connective tissue disease : generalized morphea , lichen sclerosus , fasciitis , discoid lupus erythematosus , and lupus panniculitis .
nichd_parent_of
{ "id": "C0009782", "name": "connective tissue disease", "pos": [ 36, 61 ] }
{ "id": "C0015645", "name": "fasciitis", "pos": [ 105, 114 ] }
the disease syndrome caused by this gene has been diagnosed as an analogue of niemann-pick disease in humans .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 4, 11 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 12, 20 ] }
quantitative aspects of calcium precipitation by antimonate in 45ca-labeled cacl2 solutions were examined over a wide range of calcium concentrations .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 0, 12 ] }
{ "id": "C1514721", "name": "range", "pos": [ 118, 123 ] }
od values obtained by elisa showed a log-linear relation to concentration of specific antibody in whole and affinity-chromatographed human sera measured by quantitative precipitation over a range of 0.25 to 3.5 microgram/ml .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 156, 168 ] }
{ "id": "C1514721", "name": "range", "pos": [ 190, 195 ] }
( 1 ) the activity of the endogenously active salivary burster neurones ( sbs ) shows temperature acclimation and has characteristic cold and warm blockade temperatures .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 118, 132 ] }
{ "id": "C0039476", "name": "temperatures", "pos": [ 156, 168 ] }
both procedures have been used to follow the time course of anti-proteolipid antibody production in rabbits and to compare different immunization protocols .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 5, 15 ] }
{ "id": "C0020971", "name": "immunization", "pos": [ 133, 145 ] }
the following abnormalities were found with decreasing frequency : depression and elevation of the st segment , prolongation of the qt interval , flattening and inversion of the t wave , u waves and tu fusion waves , and arrhythmias ( sinus tachycardia and bradycardia , extrasystole ) .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmias", "pos": [ 221, 232 ] }
{ "id": "C0428977", "name": "bradycardia", "pos": [ 257, 268 ] }
superior vena cava syndrome in childhood and adolescence : a review of the literature and report of three cases .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 31, 40 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 45, 56 ] }
mediastinal tumors are the main primary causes of the superior vena cava syndrome ( svcs ) in childhood and adolescence .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 94, 103 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 108, 119 ] }
doses ( sc ) of these stimulants which were well tolerated in untreated animals elicited severe ventricular dysrhythmias , often leading to death in ventricular fibrillation .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular dysrhythmias", "pos": [ 96, 120 ] }
{ "id": "C0042510", "name": "ventricular fibrillation", "pos": [ 149, 173 ] }
under conditions of both low and high stringency , hybridization analysis of virus collected between 1975 and 1980 suggested that the variation among rotavirus strains may have occurred by a process involving both `` '' drift '' '' and `` '' shift '' '' in the sequence of the rotavirus genomic segments .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 77, 82 ] }
{ "id": "C0035870", "name": "the rotav", "pos": [ 273, 282 ] }
experience indicates that pelvic node dissection does not increase the morbidity associated with cystectomy , can cure some patients with metastatic disease , effectively controls pelvic disease and indicates which patients are at substantial risk for systemic metastatic disease , implying the need for development and use of systemic chemotherapy .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 149, 156 ] }
{ "id": "C0442893", "name": "systemic", "pos": [ 327, 335 ] }
in our case there is transition of the tumor from normal squamous epithelial lining of the cyst to malignancy .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 39, 44 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 99, 109 ] }
we present here a case of sudden onset of wretching and vomiting after iv infusion of cis-platinum for recurrent carcinoma of the uterine cervix in which the patient had profuse hematemesis secondary to three posterior gastroesophageal tears requiring operative intervention after failure of nonsurgical management .
nichd_parent_of
{ "id": "C0042963", "name": "vomiting", "pos": [ 56, 64 ] }
{ "id": "C0018926", "name": "hematemesis", "pos": [ 178, 189 ] }
primary tumors included 16 osteogenic sarcomas , 9 malignant melanomas , 12 soft tissue sarcomas , 1 ewing 's sarcoma , 2 adenocarcinomas of the rectum , and 1 testicular teratocarcinoma .
nichd_parent_of
{ "id": "C1261473", "name": "soft tissue sarcomas", "pos": [ 76, 96 ] }
{ "id": "C0553580", "name": "ewing 's sarcoma", "pos": [ 101, 117 ] }
with reference to disease site , the greatest number of questions on both examinations dealt with gynecological issues while the fewest dealt with lung and hematologic-related disease .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 18, 25 ] }
{ "id": "C0018939", "name": "hematologic", "pos": [ 156, 167 ] }
to evaluate the reliability of quantitative extrapolation of radiation-induced chromosomal damage from somatic cells to germ cells , data on the effects of several biological and physical factors on the chromosomal radiosensitivity of blood lymphocytes and stem-cell spermatogonia have been collected from the literature .
nichd_parent_of
{ "id": "C0220825", "name": "evaluate", "pos": [ 3, 11 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 179, 187 ] }
we now report that in two different human sarcoma cell lines , a fibrosarcoma and an embryonal rhabdomyosarcoma , the dnas have transforming activity .
nichd_parent_of
{ "id": "C1261473", "name": "sarcoma", "pos": [ 42, 49 ] }
{ "id": "C0016057", "name": "fibrosarcoma", "pos": [ 65, 77 ] }
the binding constants between the drug substances and alpha 1-acid glycoprotein were found to be about a thousand times higher than the binding constants between the drug substances and albumin .
nichd_parent_of
{ "id": "C0439861", "name": "substances", "pos": [ 39, 49 ] }
{ "id": "C1254351", "name": "drug substances", "pos": [ 166, 181 ] }
the surgical implications of such pan-medullary tumours are discussed , the authors emphasize the aspects that in their opinion indicate exploratory surgery and , when possible , total removal of the tumours .
nichd_parent_of
{ "id": "C0543467", "name": "surgical", "pos": [ 4, 12 ] }
{ "id": "C0015250", "name": "total removal", "pos": [ 179, 192 ] }
children qualifying for the significant attention deficit group were characterized by a greater likelihood of having behavioral problems during the toddler and preschool years .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 0, 8 ] }
{ "id": "C0682053", "name": "toddler", "pos": [ 148, 155 ] }
[ dysgenetic changes of the iris and cornea associated with progressive congenital cataract and dental changes in subjects belonging to the same family ] .
nichd_parent_of
{ "id": "C0000768", "name": "dysgenetic", "pos": [ 2, 12 ] }
{ "id": "C0009691", "name": "congenital cataract", "pos": [ 72, 91 ] }
immunizing antigens against only 10 bacterial diseases-cholera , diphtheria , paratyphoid , pertussis , plague , scarlet fever , staphylococcal disease , tetanus , tuberculosis and typhoid-have been licensed for sale in canada and the united states .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial diseases", "pos": [ 36, 54 ] }
{ "id": "C0012546", "name": "diphtheria", "pos": [ 65, 75 ] }
immunizing antigens against only 10 bacterial diseases-cholera , diphtheria , paratyphoid , pertussis , plague , scarlet fever , staphylococcal disease , tetanus , tuberculosis and typhoid-have been licensed for sale in canada and the united states .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial diseases", "pos": [ 36, 54 ] }
{ "id": "C0032064", "name": "plague", "pos": [ 104, 110 ] }
immunizing antigens against only 10 bacterial diseases-cholera , diphtheria , paratyphoid , pertussis , plague , scarlet fever , staphylococcal disease , tetanus , tuberculosis and typhoid-have been licensed for sale in canada and the united states .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial diseases", "pos": [ 36, 54 ] }
{ "id": "C0036285", "name": "scarlet fever", "pos": [ 113, 126 ] }
immunizing antigens against only 10 bacterial diseases-cholera , diphtheria , paratyphoid , pertussis , plague , scarlet fever , staphylococcal disease , tetanus , tuberculosis and typhoid-have been licensed for sale in canada and the united states .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial diseases", "pos": [ 36, 54 ] }
{ "id": "C0039614", "name": "tetanus", "pos": [ 154, 161 ] }
immunizing antigens against only 10 bacterial diseases-cholera , diphtheria , paratyphoid , pertussis , plague , scarlet fever , staphylococcal disease , tetanus , tuberculosis and typhoid-have been licensed for sale in canada and the united states .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial diseases", "pos": [ 36, 54 ] }
{ "id": "C0041296", "name": "tuberculosis", "pos": [ 164, 176 ] }
immunizing antigens against only 10 bacterial diseases-cholera , diphtheria , paratyphoid , pertussis , plague , scarlet fever , staphylococcal disease , tetanus , tuberculosis and typhoid-have been licensed for sale in canada and the united states .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial diseases", "pos": [ 36, 54 ] }
{ "id": "C0041466", "name": "typhoid", "pos": [ 181, 188 ] }
[ studies on the surgical management of cerebral apoplexy . i. the effect of experimental intracerebral hemorrhage on glutamic oxalacetic transaminase and lactic dehydrogenase in serum and cerebrospinal fluid ] .
nichd_parent_of
{ "id": "C0038454", "name": "cerebral apoplexy", "pos": [ 40, 57 ] }
{ "id": "C2937358", "name": "intracerebral hemorrhage", "pos": [ 90, 114 ] }
primary malignant neoplasms of nerves ( malignant neurilemomas ) in patients without manifestations of multiple neurofibromatosis ( von recklinghausen 's disease ) .
nichd_parent_of
{ "id": "C0162678", "name": "multiple neurofibromatosis", "pos": [ 103, 129 ] }
{ "id": "C0027831", "name": "von recklinghausen", "pos": [ 132, 150 ] }
sarcomas of the peripheral nerves and somatic soft tissues associated with multiple neurofibromatosis ( von recklinghausen 's disease ) .
nichd_parent_of
{ "id": "C0162678", "name": "multiple neurofibromatosis", "pos": [ 75, 101 ] }
{ "id": "C0027831", "name": "von recklinghausen", "pos": [ 104, 122 ] }
[ the problem of epileptic seizures and eeg hypersyndronism in cerebral palsy in children ( little 's disease ) ] .
nichd_parent_of
{ "id": "C0007789", "name": "cerebral palsy", "pos": [ 63, 77 ] }
{ "id": "C0023882", "name": "little", "pos": [ 92, 98 ] }
[ importance of the ciliary plexus in the physiopathological mechanism of general and ocular disorders associated with glaucoma ] .
nichd_parent_of
{ "id": "C0015397", "name": "ocular disorders", "pos": [ 86, 102 ] }
{ "id": "C0017601", "name": "glaucoma", "pos": [ 119, 127 ] }
the discipline and dynamics of active case detection procedure under surveillance operation in a malaria eradication programme .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 53, 62 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 82, 91 ] }
increased storage iron was found in some cases of infection , malignancy , and in blood and hepatic diseases , while low stores were present in other cases with malignancy and in polycythaemia vera .
nichd_parent_of
{ "id": "C0006826", "name": "malignancy", "pos": [ 62, 72 ] }
{ "id": "C0032463", "name": "polycythaemia", "pos": [ 179, 192 ] }
other clinical signs were less conspicuous and consisted of anorexia , stiff gait , and arched back occurring only on the third and fourth days after inoculation .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 6, 20 ] }
{ "id": "C0003123", "name": "anorexia", "pos": [ 60, 68 ] }
a series of small cation molybdates , mgmoo ( 4 ) , mnmoo ( 4 ) , femoo ( 4 ) , comoo ( 4 ) , nimoo ( 4 ) , and znmoo ( 4 ) with the wolframite structure characteristic of the corresponding tungstates have been synthesized at high pressure and temperature .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 154, 168 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 244, 255 ] }
the author emphasizes that chemosterilants can not at present be recommended as a practical control or eradication procedure for any vector species of insect , but considers that this extension of the sterilization method holds great promise and merits intensive investigation .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 115, 124 ] }
{ "id": "C0220825", "name": "investigation", "pos": [ 263, 276 ] }
the procedures used in the organization and operation of a special study on diarrheal diseases involving federal , state , and local agencies are outlined .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 4, 14 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 44, 53 ] }
[ suitability of the characteristic blood pressure diagram in evaluation of variations of excitability in the reflex arc ] .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 21, 35 ] }
{ "id": "C0005823", "name": "blood pressure", "pos": [ 36, 50 ] }
[ biological methods in diagnosis of mumps ; determination of blood amylase as a test of infection ] .
nichd_parent_of
{ "id": "C0430022", "name": "methods", "pos": [ 13, 20 ] }
{ "id": "C0022885", "name": "test", "pos": [ 81, 85 ] }
[ results of penicillin therapy of syphilis in pregnancy and its effect on prevention of congenital syphilis ] .
nichd_parent_of
{ "id": "C0039128", "name": "syphilis", "pos": [ 35, 43 ] }
{ "id": "C0039131", "name": "congenital syphilis", "pos": [ 89, 108 ] }
procedures that would incorporate pertinent histochemical properties into one simplified assay for the successful differentiation and determination of fiber types were evaluated using muscle samples from three different species ( ovine , bovine and porcine ) .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 0, 10 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 168, 177 ] }
the ability to make a quantitative visualization of altered patterns of end-capillary po2 provides an additional dimension to the investigation of stroke disease and tumor metabolism .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 154, 161 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 166, 171 ] }
patients presented with recurrent intestinal obstruction in childhood or adolescence : eight of the 11 died before the age of 30 .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 60, 69 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 73, 84 ] }
this finding was found histologically in four of eight cases of moivc , and it is a useful finding in the ct diagnosis of moivc .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 5, 12 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 109, 118 ] }
( b ) when the sellar-suprasellar mass was markedly constricted at the diaphragma sellae on mr sagittal slices ( 16 cases ) , transsphenoidal surgical approach was not only insufficient for total removal but could be dangerous , as the remaining suprasellar portion may rapidly increase in size following surgery from postoperative hemorrhage and/or acute edema with severe obstructive hydrocephalus ( three cases ) and/or acute blindness ( two cases ) ;
nichd_parent_of
{ "id": "C0543467", "name": "surgical", "pos": [ 142, 150 ] }
{ "id": "C0015250", "name": "total removal", "pos": [ 190, 203 ] }
the collateral supply was assessed in 6 reference hearts without infarction , 4 hearts with a transmural infarct and 12 hearts with a total of 16 subendocardial infarcts .
nichd_parent_of
{ "id": "C0021308", "name": "infarction", "pos": [ 65, 75 ] }
{ "id": "C0027051", "name": "hearts", "pos": [ 120, 126 ] }
the finding that most ( 90 % ) of these isolates belonged to the same biotype and serotype suggested that the patient had relapsing infections with the same strain .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 4, 11 ] }
{ "id": "C3714514", "name": "infections", "pos": [ 132, 142 ] }
the primary mechanism of death in sids is considered to be irreversible respiratory cessation during sleep .
nichd_parent_of
{ "id": "C0011065", "name": "death", "pos": [ 25, 30 ] }
{ "id": "C0038644", "name": "sids", "pos": [ 34, 38 ] }
the results of flow cytometry analysis employing a panel of mabs against live t. foetus parasites revealed that from 5 to 84 % of individuals in a given population of t. foetus expressed a particular epitope of the 150 ag .
nichd_parent_of
{ "id": "C0027361", "name": "individuals", "pos": [ 130, 141 ] }
{ "id": "C0015965", "name": "foetus", "pos": [ 170, 176 ] }
a case of fetal urinary tract obstruction , although apparently an isolated defect , proved to be associated with a lethal chromosome abnormality , trisomy 18 mosaicism .
nichd_parent_of
{ "id": "C0008625", "name": "chromosome abnormality", "pos": [ 123, 145 ] }
{ "id": "C0152096", "name": "trisomy 18", "pos": [ 148, 158 ] }
the finding that only syncytium-inducing isolates could be transmitted to the h9 cell line is compatible with this higher infectivity .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 4, 11 ] }
{ "id": "C0242781", "name": "transmitted", "pos": [ 59, 70 ] }
the antibodies directed against the hpv-6b fusion proteins showed no cross-reactivity with comparable regions of the hpv-16 orfs .
nichd_parent_of
{ "id": "C0021344", "name": "hpv", "pos": [ 36, 39 ] }
{ "id": "C0999806", "name": "hpv-16", "pos": [ 117, 123 ] }
we conclude that brief submaximal maternal exercise up to approximately 70 % of maximal aerobic power ( maternal heart rate less than or equal to 148 beats per minute ) does not affect fetal heart rate .
nichd_parent_of
{ "id": "C0018810", "name": "heart rate", "pos": [ 113, 123 ] }
{ "id": "C0018811", "name": "fetal heart rate", "pos": [ 185, 201 ] }