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there is evidence of an increased incidence of malignancy in other forms of autoimmune disease , and this may represent a further contributing factor to the development of primary liver cell cancer in cases of chronic active hepatitis .
nichd_parent_of
{ "id": "C0006826", "name": "malignancy", "pos": [ 47, 57 ] }
{ "id": "C0024620", "name": "the", "pos": [ 153, 156 ] }
we described our methods of screening mice for inborn errors of metabolism including metabolic storage diseases , disorders of amino acid metabolism , and organic acidemias .
nichd_parent_of
{ "id": "C0025521", "name": "inborn errors of metabolism", "pos": [ 47, 74 ] }
{ "id": "C0002514", "name": "disorders of amino acid metabolism", "pos": [ 114, 148 ] }
fifteen tuberculin positive rhesus monkeys with disseminated tuberculosis were evaluated for extent of disease by radiographic techniques , physical examination and laparotomy prior to treatment .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 79, 88 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 140, 160 ] }
in the light of these data , monitoring the type of viral infection proves to be an important adjunct to histological analysis when assessing those patients affected by condyloma or cervical intra-epithelial neoplasia who are at risk for developing invasive carcinoma .
nichd_parent_of
{ "id": "C0042769", "name": "viral infection", "pos": [ 52, 67 ] }
{ "id": "C0009663", "name": "condyloma", "pos": [ 169, 178 ] }
quantitative measurements of static twist were obtained over the entire temperature and media range , providing a detailed picture of the dependence of twist upon these environmental influences .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 0, 12 ] }
{ "id": "C1514721", "name": "range", "pos": [ 94, 99 ] }
the author presents evidence from published papers of research done by numerous investigators that multiple , sclerosis ( ms ) is an autoimmune disease , that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord , that myelin basic protein ( mbp ) is the antigen or one of the antigens involved , that the autoimmune reaction is effected by sensitized lymphocytes together with a specific antibody , that experimental allergic encephalomyelitis ( eae ) produced in animals can be used as a model for ms , and that the autoimmune reaction in ms can possibly be suppressed by the use of mbp given by an intravenous procedure together with an immunosuppressive drug and a corticosteroid .
nichd_parent_of
{ "id": "C0004364", "name": "autoimmune disease", "pos": [ 133, 151 ] }
{ "id": "C0026769", "name": "ms", "pos": [ 586, 588 ] }
bacterial tests can be used for several related purposes : the screening for genotoxic agents , genetic analysis of the mode of action of genotoxins and attempts to predict their effects in mammals .
nichd_parent_of
{ "id": "C0022885", "name": "tests", "pos": [ 10, 15 ] }
{ "id": "C0679560", "name": "genetic analysis", "pos": [ 96, 112 ] }
the authors , finding embarrassment and unpreparedness from the italian physician in such a situation , intend to provide with this work a correct diagnostic-therapeutic iter to be followed in a case of snakebite .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 14, 21 ] }
{ "id": "C0011900", "name": "diagnostic", "pos": [ 147, 157 ] }
during childhood and adolescence , the rate of malignancy in ovarian enlargement is reported to be high-approximately 35 % in many large series from tertiary centers .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 7, 16 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 21, 32 ] }
substances that irritate or stimulate the colon , such as unabsorbed fat , bile acids , bacterial enterotoxins and laxatives and excessive delivery of fluid from the small intestine , flush out colonic contents by causing secretion and colonic propulsion .
nichd_parent_of
{ "id": "C0439861", "name": "substances", "pos": [ 0, 10 ] }
{ "id": "C0005889", "name": "fluid", "pos": [ 151, 156 ] }
tuberculosis and sexually transmitted diseases other than syphilis ( which shares second place with influenza ) and measles ( in fourth place ) , diminish importantly among the gps ' selections as their age rises , thus calling our attention to the role experience plays in the choices and , very probably , to the nature of their clientele .
nichd_parent_of
{ "id": "C0036916", "name": "sexually transmitted diseases", "pos": [ 17, 46 ] }
{ "id": "C0039128", "name": "syphilis", "pos": [ 58, 66 ] }
at our four hospital-based pain management centers we have evaluated and treated more than 5,000 patients for chronic pain .
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 27, 31 ] }
{ "id": "C0150055", "name": "chronic pain", "pos": [ 110, 122 ] }
the clinical symptoms of disease were shown to be caused by structural changes in the intestinal mucous membrane leading to a syndrome of intolerance of some nutrients .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 25, 32 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 126, 134 ] }
on the contrary the continuous intake of small amounts leads to chronic intoxications which are characterized by loss of weight , insufficient gain in weight , fertility disorder or increased susceptibility for infectious diseases .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 170, 178 ] }
{ "id": "C0009450", "name": "infectious diseases", "pos": [ 211, 230 ] }
these results provide a remarkable example where in the same cells doubly infected with two different viruses , the antiviral state induced by ifn-alpha is manifested by selectively inhibiting translation of one kind of virus ( poliovirus or vesicular stomatitis virus ) without affecting the translation of reovirus type 3 .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 102, 107 ] }
{ "id": "C0206435", "name": "poliovirus", "pos": [ 228, 238 ] }
with respect to the relationship of antibody profile and illness , both methods demonstrated a high frequency of antibodies against u1-sn-rnp in mixed connective tissue disease and of anti-ss-b antibodies in sjogren 's syndrome .
nichd_parent_of
{ "id": "C0003241", "name": "antibody", "pos": [ 36, 44 ] }
{ "id": "C0443933", "name": "anti-ss-b antibodies", "pos": [ 184, 204 ] }
the method of choice worldwide is the typical cimino fistula on the distal forearm , but a more peripheral arterio-venous fistula is possible .
nichd_parent_of
{ "id": "C0016169", "name": "fistula", "pos": [ 53, 60 ] }
{ "id": "C0003855", "name": "arterio-venous fistula", "pos": [ 107, 129 ] }
the patients with significant abnormalities usually had head circumferences greater than the 95th percentile and had neurologic abnormalities .
nichd_parent_of
{ "id": "C0000768", "name": "abnormalities", "pos": [ 30, 43 ] }
{ "id": "C0497552", "name": "neurologic abnormalities", "pos": [ 117, 141 ] }
sonography is the initial procedure recommended since it accurately evaluates ventricular size , extraaxial fluid , and congenital malformations .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 26, 35 ] }
{ "id": "C0220825", "name": "evaluates", "pos": [ 68, 77 ] }
a total of 224 children was enrolled in the center during the study period : 29 infants ( ages 0 to 16 months ) , 62 toddlers ( 16.1 to 30 months ) , and 133 preschoolers ( 30.1 to 72 months ) .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 15, 23 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 80, 87 ] }
the bite rates ( defined as number of bites per 100 child days of enrollment in the center ) varied significantly by age group but not by gender for initial or first-time bites , with toddlers having the highest rate and preschoolers the lowest ( infants , 0.7129 ; toddlers , 1.3672 ; preschoolers , 0.4193 ) .
nichd_parent_of
{ "id": "C0008059", "name": "child", "pos": [ 52, 57 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 247, 254 ] }
total bite rates ( which took into account multiple bites per child over the 12-month study period ) varied significantly by age group , with toddlers having the highest rate per 100 days of enrollment and preschoolers the lowest ( infants , 2.1931 ; toddlers , 3.1300 ; preschoolers , 0.5611 ) .
nichd_parent_of
{ "id": "C0008059", "name": "child", "pos": [ 62, 67 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 232, 239 ] }
the disease may be confused with spotless rocky mountain spotted fever but can be differentiated from this infection serologically with acute and convalescent sea .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 4, 11 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 107, 116 ] }
no evidence for a discernible pattern justifying these rulings emerged from an examination of petitioner and court characteristics such as age , length of hearing , number of weeks pregnant , or presiding judge .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 115, 130 ] }
{ "id": "C1444754", "name": "length", "pos": [ 145, 151 ] }
a stool survey of the handicapped group showed that of the 20 persons tested , nine were positive for giardia , including the specimen from this child .
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 62, 69 ] }
{ "id": "C0008059", "name": "child", "pos": [ 145, 150 ] }
all patients were treated with appropriate antibiotics and a single operative procedure consisting of preliminary extraanatomic bypass followed by complete aneurysm excision and posterior drainage of the retroperitoneum .
nichd_parent_of
{ "id": "C0543467", "name": "operative procedure", "pos": [ 68, 87 ] }
{ "id": "C0015250", "name": "complete", "pos": [ 147, 155 ] }
the various definitions and classifications of megalencephaly are reviewed , and numerous diseases and syndromes associated with megalencephaly are listed .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 90, 98 ] }
{ "id": "C0039082", "name": "syndromes", "pos": [ 103, 112 ] }
a new method is described for pediatric otologic exploration : cochlear acoustic emissions ( cae ) , and results reported of cae recordings in 15 children with normal hearing and 31 infants at otoneurologic risk , suspected of having moderate or severe hypoacusia on conventional audiometry .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 146, 154 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 182, 189 ] }
the incidence of cae in children and infants with normal hearing was 100 % , the absence of cae being related to a v ware threshold of aep of 30 db nhl or more .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 24, 32 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 37, 44 ] }
these potentials retain their significance of tracers of ventricular arrhythmias in primary dilated myocardiopathies , with a prevalence of 25 p. cent reaching 50 p. cent in case of ventricular tachycardia .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 57, 80 ] }
{ "id": "C0042514", "name": "ventricular", "pos": [ 182, 193 ] }
subcortical dementia occurs both in disorders affecting the basal ganglia ( for example , parkinson 's disease , huntington 's disease , and progressive supranuclear palsy ) and in a variety of subcortical vascular , infectious , inflammatory , neoplastic , and traumatic conditions .
nichd_parent_of
{ "id": "C0012634", "name": "disorders", "pos": [ 36, 45 ] }
{ "id": "C0009450", "name": "infectious", "pos": [ 217, 227 ] }
the radiologic appearance of atypical cardiogenic pulmonary edema ( acpe ) is presented in 10 cases admitted from 1983 to 1985 , with age ranges from 74 to 89 , and with diagnosis of ischemic heart disease , with myocardial infarction in 50 % of them .
nichd_parent_of
{ "id": "C0018799", "name": "of", "pos": [ 26, 28 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 213, 234 ] }
an elisa test , a tuberculin test and a t4-lymphocyte count were performed in all patients .
nichd_parent_of
{ "id": "C0022885", "name": "test", "pos": [ 9, 13 ] }
{ "id": "C0041290", "name": "tuberculin test", "pos": [ 18, 33 ] }
systemic investigation of the mechanisms that control locomotions in the man provides elaboration of some problems concerning properties and construction of the locomotory apparatus , especially morphometric characteristics of the muscles -- length and shoulder of the thrust force .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 208, 223 ] }
{ "id": "C1444754", "name": "length", "pos": [ 242, 248 ] }
the investigation has been performed on 107 renal preparations obtained from persons of various age ( from 5-month-old fetuses up to 45 years of age ) , certain representatives of other classes of the vertebrata are also included : fish , amphibia , reptile and mammalia at various stages of pre- and postnatal periods of ontogenesis by means of preparing graphic and plastic reconstructive models , histological investigation and microdissection .
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 77, 84 ] }
{ "id": "C0015965", "name": "fetuses", "pos": [ 119, 126 ] }
this short-term favorable prognosis for abstinence-associated seizures differs from that associated with neonatal seizures due to other causes .
nichd_parent_of
{ "id": "C0036572", "name": "seizures", "pos": [ 62, 70 ] }
{ "id": "C0159020", "name": "neonatal seizures", "pos": [ 105, 122 ] }
linear-cubic equations were fitted to the data of individual fetuses and from these equations mean growth curves were produced for males and females .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 50, 60 ] }
{ "id": "C0015965", "name": "fetuses", "pos": [ 61, 68 ] }
concomitant zoonotic infections with ovine chlamydia and ' q ' fever in pregnancy : clinical features , diagnosis , management and public health implications .
nichd_parent_of
{ "id": "C0043528", "name": "zoonotic infections", "pos": [ 12, 31 ] }
{ "id": "C0034362", "name": "q", "pos": [ 59, 60 ] }
the finding of anaemia together with cutaneous and intestinal haemangiomas fits with a diagnosis of blue rubber-bleb naevus syndrome .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 4, 11 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 87, 96 ] }
drusch s.a. in collaboration with institut d ' electronique fondamentale built the system with the following characteristics : weight : 12 t , pole diameter : 55 cm , distance between coils : 36 cm .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 109, 124 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 127, 133 ] }
management evaluation must be specific , comprehensive , and targeted by scientific studies , risk group and temporal analyses , physical examination , and laboratory diagnosis .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 11, 21 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 129, 137 ] }
cancers with low overall 5-year relative survival rates ( less than 35 % ) included stomach cancer , cancer of the pancreas , lung cancer , brain cancer , multiple myeloma and myeloid leukemia .
nichd_parent_of
{ "id": "C0006826", "name": "cancers", "pos": [ 0, 7 ] }
{ "id": "C0153633", "name": "brain cancer", "pos": [ 140, 152 ] }
cancers with high overall 5-year relative survival rates ( more than 70 % ) included melanoma , breast cancer , cancer of the uterus , cancer of the bladder and hodgkin 's disease .
nichd_parent_of
{ "id": "C0006826", "name": "cancers", "pos": [ 0, 7 ] }
{ "id": "C0025202", "name": "included", "pos": [ 76, 84 ] }
the other one appears to be restricted to the malignant tumor and represents a novel melanoma-associated ganglioside derivative .
nichd_parent_of
{ "id": "C0006826", "name": "malignant tumor", "pos": [ 46, 61 ] }
{ "id": "C0025202", "name": "associated", "pos": [ 94, 104 ] }
clinical and epidemiological data have implicated the human papillomaviruses ( hpvs ) as having an etiologic role in some anogenital malignancies , with hpv-16 being most frequently ( greater than 60 % ) detected in cervical carcinoma .
nichd_parent_of
{ "id": "C0021344", "name": "human papillomaviruses", "pos": [ 54, 76 ] }
{ "id": "C0999806", "name": "hpv-16", "pos": [ 153, 159 ] }
clinical and epidemiological data have implicated the human papillomaviruses ( hpvs ) as having an etiologic role in some anogenital malignancies , with hpv-16 being most frequently ( greater than 60 % ) detected in cervical carcinoma .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 133, 145 ] }
{ "id": "C0302592", "name": "cervical carcinoma", "pos": [ 216, 234 ] }
when the behaviour of different variables was considered then some ( including urinary potassium and melatonin , sleep length and rem sleep ) appeared to possess a larger endogenous component than others ( for example , urinary sodium , phosphate and calcium ) , with rectal temperature behaving in an intermediate manner .
nichd_parent_of
{ "id": "C0004927", "name": "behaviour", "pos": [ 9, 18 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 134, 139 ] }
we have prospectively evaluated 49 consecutive survivors of aso for tga with intact ventricular septum ( ivs ) by clinical examination , echocardiography , cardiac catheterization , ambulatory electrocardiographic monitoring , and invasive electrophysiologic studies .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 22, 31 ] }
{ "id": "C0031809", "name": "clinical examination", "pos": [ 114, 134 ] }
in children clearance is similar to that in adults when expressed as a function of bodyweight , but in neonates , especially in low birthweight infants , it is less [ about 1 ml/min/kg ( 0.06 l/h/kg ) ] .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 3, 11 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 103, 111 ] }
non-insulin-dependent diabetes mellitus ( niddm ) is a very common disorder , but less attention is paid to it than to the more dramatic but less prevalent insulin-dependent diabetes .
nichd_parent_of
{ "id": "C0011849", "name": "non-insulin-dependent diabetes mellitus", "pos": [ 0, 39 ] }
{ "id": "C0011854", "name": "insulin-dependent diabetes", "pos": [ 156, 182 ] }
clinical signs involving the gastrointestinal tract , adverse effects on body weight gain , consistent biochemical changes in serum proteins , calcium , inorganic phosphorus and serum cholesterol were recorded at 4 mg/kg per day and above .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0043094", "name": "body weight gain", "pos": [ 73, 89 ] }
hemoglobin saturation as measured by pulse oximetry correlated significantly with pao2 ( r = .65 , p less than .0001 ) ;
nichd_parent_of
{ "id": "C0523807", "name": "hemoglobin saturation", "pos": [ 0, 21 ] }
{ "id": "C0034108", "name": "pulse oximetry", "pos": [ 37, 51 ] }
the occurrence of such seizures after recovery from bect is a rare event ( approximately 2 % of cases ) and a relapse with partial seizures is quite uncommon .
nichd_parent_of
{ "id": "C0036572", "name": "seizures", "pos": [ 23, 31 ] }
{ "id": "C0751495", "name": "partial seizures", "pos": [ 123, 139 ] }
significantly elevated concentrations of pge-2 were also found in febrile children without seizures , although the mean pge-2 level in these patients was somewhat lower than that determined after a febrile convulsion .
nichd_parent_of
{ "id": "C0036572", "name": "seizures", "pos": [ 91, 99 ] }
{ "id": "C0009952", "name": "febrile", "pos": [ 198, 205 ] }
one factor ( factor 4 ) involved pain in the neck , pain in the back , pain in arms and shoulders , and migraine .
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 33, 37 ] }
{ "id": "C0004604", "name": "pain", "pos": [ 71, 75 ] }
anti-inflammatory agents do not affect the pain , but due to the incomplete understanding of the action of these drugs , the role of inflammation in delayed onset muscle pain is uncertain .
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 43, 47 ] }
{ "id": "C0231528", "name": "muscle pain", "pos": [ 163, 174 ] }
in rats , maternal toxicity was observed at 1.0 and 2.5 ml/kg , as evidenced by reduced weight gain and food consumption during treatment , clinical signs of toxicity , reduced body weight on gd 21 ( corrected for gravid uterine weight ) , and increased relative liver weight .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 140, 154 ] }
{ "id": "C0043094", "name": "increased", "pos": [ 244, 253 ] }
clinical signs in mice were squinting and distended testes in males , and in rats , rapid respiration ( all doses ) , squinting , and hunching .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0231835", "name": "rapid respiration", "pos": [ 84, 101 ] }
inversely , unlabelled igm rf and anti-id rf inhibited the binding of 125i-igm rf markedly and unlabelled human igg and igg fc only slightly or moderately , respectively .
nichd_parent_of
{ "id": "C0003241", "name": "anti-id rf", "pos": [ 34, 44 ] }
{ "id": "C0035448", "name": "anti-id rf", "pos": [ 34, 44 ] }
a thrombotic microangiopathy syndrome , clinically and pathologically similar to thrombotic thrombocytopenic purpura ( ttp ) has been reported in recipients of tissue transplants , including renal and bone marrow allografts .
nichd_parent_of
{ "id": "C2717961", "name": "thrombotic microangiopathy", "pos": [ 2, 28 ] }
{ "id": "C0034155", "name": "thrombotic thrombocytopenic purpura", "pos": [ 81, 116 ] }
the changed adhesiveness thus seemed to have affected the tumor latency period , the speed of dissemination into blood and internal organs , the mode of organ infiltration ( focal vs. diffuse ) and of metastatic growth , parameters which all might contribute to the greatly reduced overall malignancy .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 58, 63 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 290, 300 ] }
since trends in the incidence of other sexually transmitted diseases may be a good marker of such behavioral changes , gonorrhea incidence in the civilian and military populations in israel was examined during the period 1963-87 .
nichd_parent_of
{ "id": "C0036916", "name": "sexually transmitted diseases", "pos": [ 39, 68 ] }
{ "id": "C0018081", "name": "gonorrhea", "pos": [ 119, 128 ] }
due to the apparent benign course of syphilis in this ethnic group and recent evidence that lumbar puncture is not mandatory in patients with latent syphilis or asymptomatic neurosyphilis , we suggest that csf should not be routinely examined in these patients .
nichd_parent_of
{ "id": "C0039128", "name": "syphilis", "pos": [ 37, 45 ] }
{ "id": "C0039133", "name": "latent", "pos": [ 142, 148 ] }
the procedure for determining gfr by use of nuclear medicine was rapid and noninvasive and appeared to induce little stress in the animals evaluated .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 139, 148 ] }
pulmonary edema after re-expansion of a pneumothorax occurs within a maximum of 3 days of the pneumothorax and manifests by intense clinical signs ( cough , abundant foamy expectoration , major cyanosis ) , marked hypoxia and a `` '' white lung '' '' radiologic image .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 132, 146 ] }
{ "id": "C0010200", "name": "cough", "pos": [ 149, 154 ] }
pulmonary edema after re-expansion of a pneumothorax occurs within a maximum of 3 days of the pneumothorax and manifests by intense clinical signs ( cough , abundant foamy expectoration , major cyanosis ) , marked hypoxia and a `` '' white lung '' '' radiologic image .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 132, 146 ] }
{ "id": "C0010520", "name": "cyanosis", "pos": [ 194, 202 ] }
the programs are aimed at the uninsured and underinsured , the farming and rural community , the urban poor , the homeless , the developmentally disabled , persons with aids , senior citizens , children , and the hispanic community .
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 156, 163 ] }
{ "id": "C0008059", "name": "children", "pos": [ 194, 202 ] }
parent-child correspondence for the presence or absence of individual behaviors and firesetting correlates was generally moderate-to-high for both samples , with outpatient families showing higher parent-child agreement in classifying the child 's firesetting status .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 59, 69 ] }
{ "id": "C0008059", "name": "child 's", "pos": [ 239, 247 ] }
a high-performance liquid chromatographic ( hplc ) procedure has been evaluated to establish a routine test in the clinical laboratory for measuring the profiles of estrogen and progestin receptor isoforms in human breast and endometrial tumors .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 51, 60 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 70, 79 ] }
the women were divided into three groups : those with anatomical anomalies of the cervix , abnormalities of the cervical mucus and a negative pct and normal parameters in cervical mucus .
nichd_parent_of
{ "id": "C0302142", "name": "anatomical anomalies", "pos": [ 54, 74 ] }
{ "id": "C0000768", "name": "abnormalities", "pos": [ 91, 104 ] }
more than a hundred years of parasitic zoonoses : with special reference to trichinosis and hydatid disease .
nichd_parent_of
{ "id": "C0043528", "name": "zoonoses", "pos": [ 39, 47 ] }
{ "id": "C0040896", "name": "trichinosis", "pos": [ 76, 87 ] }
more than a hundred years of parasitic zoonoses : with special reference to trichinosis and hydatid disease .
nichd_parent_of
{ "id": "C0043528", "name": "zoonoses", "pos": [ 39, 47 ] }
{ "id": "C0013502", "name": "hydatid disease", "pos": [ 92, 107 ] }
it is suggested that disease might arise through a dysfunction of the immune system following infection of host large granular lymphocytes by the sa-mcf agent , in a way similar to that suggested for the rabbit .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 21, 28 ] }
{ "id": "C0021053", "name": "dysfunction", "pos": [ 51, 62 ] }
it is suggested that disease might arise through a dysfunction of the immune system following infection of host large granular lymphocytes by the sa-mcf agent , in a way similar to that suggested for the rabbit .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 21, 28 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 94, 103 ] }
we performed thallium 201 muscle scans to assess muscular involvement in 40 patients with different connective tissue diseases ( 7 with dermatomyositis , 7 with systemic lupus erythematosus , 12 with progressive systemic scleroderma , 2 with calcinosis , raynaud 's phenomenon , esophageal involvement , sclerodactyly , and telangiectasia ( crest ) syndrome , 3 with monomelic scleroderma , 6 with morphea , and 3 with raynaud 's disease ) .
nichd_parent_of
{ "id": "C0011644", "name": "scleroderma", "pos": [ 221, 232 ] }
{ "id": "C0036420", "name": "morphea", "pos": [ 398, 405 ] }
the study was conducted to determine effects of an abraded intramammary device on milk yield , tissue damage , and milk somatic cells during late lactation .
nichd_parent_of
{ "id": "C0004927", "name": "conducted", "pos": [ 14, 23 ] }
{ "id": "C0006147", "name": "lactation", "pos": [ 146, 155 ] }
this paper will report on the use of the objective structured clinical examination ( osce ) to measure the psychomotor learning outcomes of a programme designed to assist students to learn to conduct a nursing neurological examination .
nichd_parent_of
{ "id": "C0004927", "name": "conduct", "pos": [ 192, 199 ] }
{ "id": "C0006147", "name": "nursing", "pos": [ 202, 209 ] }
in the present study on rat kidney tubules an intraluminal , electron-dense granular substance was found in animals perfusion-fixed with dextran-containing fluids .
nichd_parent_of
{ "id": "C0439861", "name": "substance", "pos": [ 85, 94 ] }
{ "id": "C0005889", "name": "fluids", "pos": [ 156, 162 ] }
mri most clearly has advantages where ct is degraded by bone hardening and streak artefacts ( spine , skull base , posterior and temporal fossa , sella and parasellar regions ) and in diseases in which the x-ray attenuation of the suspected lesion differs little from normal parenchyma ( paediatric brain disorders , demyelination and dysmyelination , early oedema associated with infarction , infection or low-grade infiltrating neoplasm , subacute and chronic haemorrhage and lesions in the spinal subarachnoid space and cord ) .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 184, 192 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 394, 403 ] }
mri most clearly has advantages where ct is degraded by bone hardening and streak artefacts ( spine , skull base , posterior and temporal fossa , sella and parasellar regions ) and in diseases in which the x-ray attenuation of the suspected lesion differs little from normal parenchyma ( paediatric brain disorders , demyelination and dysmyelination , early oedema associated with infarction , infection or low-grade infiltrating neoplasm , subacute and chronic haemorrhage and lesions in the spinal subarachnoid space and cord ) .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 184, 192 ] }
{ "id": "C0027651", "name": "neoplasm", "pos": [ 430, 438 ] }
after rinsing for 3 hr with unlabeled perfusion fluid the tumor-to-kidney tissue ratios increased to 8.6 for g250 antibody and to 2.7 for rc38 antibody .
nichd_parent_of
{ "id": "C0005889", "name": "fluid", "pos": [ 48, 53 ] }
{ "id": "C0003241", "name": "antibody", "pos": [ 143, 151 ] }
a review of the published pathologically proven cases reveals this disorder to have distinctive clinical and radiological features that allow differentiation from infection , neoplasia , and arthritides in most instances .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 67, 75 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 163, 172 ] }
a review of the published pathologically proven cases reveals this disorder to have distinctive clinical and radiological features that allow differentiation from infection , neoplasia , and arthritides in most instances .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 67, 75 ] }
{ "id": "C0027651", "name": "neoplasia", "pos": [ 175, 184 ] }
use of a population-based tumor registry to estimate cancer incidence among a cohort of chemical workers .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 26, 31 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 53, 59 ] }
two major facilities of the western division of dow chemical usa are located fortuitously within an area covered by the population-based california tumor registry , which allowed linkage of records to identify incident cancers among 1,403 male workers .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 148, 153 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 219, 226 ] }
on the basis of information obtained from a population-based cancer registry in sweden , male patients with breast cancer ( n = 95 ) were found to have experienced significantly more brain concussions and skull fractures than male patients with lung cancer ( n = 383 ) or malignant lymphoma ( n = 69 ) .
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 61, 67 ] }
{ "id": "C0024299", "name": "malignant lymphoma", "pos": [ 272, 290 ] }
although the frequency of latent prostate carcinoma and the lit : lnt in the samples obtained most recently were comparable to those of u.s. whites , cancer incidence and mortality rates remain lower in japan .
nichd_parent_of
{ "id": "C0027651", "name": "lit", "pos": [ 60, 63 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 150, 156 ] }
congenital malformations observed grossly in embryos were often multiple and included anophthalmia , microphthalmia , abnormal beaks , amelia , micromelia , ectrodactyly , and hydrocephaly .
nichd_parent_of
{ "id": "C0000768", "name": "congenital", "pos": [ 0, 10 ] }
{ "id": "C0003119", "name": "anophthalmia", "pos": [ 86, 98 ] }
congenital malformations observed grossly in embryos were often multiple and included anophthalmia , microphthalmia , abnormal beaks , amelia , micromelia , ectrodactyly , and hydrocephaly .
nichd_parent_of
{ "id": "C0000768", "name": "congenital", "pos": [ 0, 10 ] }
{ "id": "C0026010", "name": "microphthalmia", "pos": [ 101, 115 ] }
the seven other tumors showed typical histological features of colonic adenocarcinomas , but no frank evidence of parietal tumoral invasion was observed and their cancerous nature was questionable .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 16, 22 ] }
{ "id": "C0006826", "name": "cancerous", "pos": [ 163, 172 ] }
the observed changes in cystometric characteristics and length-tension relations might probably be explained on the basis of adaptive changes to the increased diuresis involving both sensory and motor control of the urinary bladder .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 36, 51 ] }
{ "id": "C1444754", "name": "length", "pos": [ 56, 62 ] }
ipsilateral infarction was most common in patients with stroke ( 76 % ) but was also seen in 32.8 % of patients with transient ischemic attacks , in 9 of 40 patients ( 22.5 % ) with nonhemispheric symptoms , and in 9 of 45 patients ( 20 % ) with asymptomatic hemodynamically significant carotid stenosis .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 56, 62 ] }
{ "id": "C0007787", "name": "transient ischemic attacks", "pos": [ 117, 143 ] }
a `` '' gold standard '' '' comparison with the results of an independent procedure , such as surgical or autopsy findings , was presented in 22 % of evaluations .
nichd_parent_of
{ "id": "C0184661", "name": "t procedu", "pos": [ 72, 81 ] }
{ "id": "C0543467", "name": "surgic", "pos": [ 94, 100 ] }
the organism is a more common pathogen in the united states than is generally recognized , and the diagnosis should be considered for patients with suspected enteric infection .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 4, 12 ] }
{ "id": "C0450254", "name": "pathogen", "pos": [ 30, 38 ] }
to investigate the utility of body surface isochrone maps for estimating ventricular arrhythmias in patients with previous myocardial infarction , we compared findings of body surface isochrone maps with those of signal-averaged electrocardiograms ( saecgs ) and an incidence of ventricular tachycardia ( vt ) .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 73, 96 ] }
{ "id": "C0042514", "name": "ventricular tachycardia", "pos": [ 279, 302 ] }
the abrupt cerebral infarction , other clinical findings , and results of diagnostic studies strongly suggested that the acute cerebrovascular event was the result of metastatic cerebral embolization from the tumor material found in the thorax .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 39, 56 ] }
{ "id": "C0011900", "name": "diagnostic", "pos": [ 74, 84 ] }
they emphasize the rarity of the condition and point out that erythrophagocytosis in the histopathological examination may be a valuable finding for the diagnosis of malignant histiocytosis .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 137, 144 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 153, 162 ] }
the majority of the tumors presented as a mass in the upper cervical or parapharyngeal region .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 20, 26 ] }
{ "id": "C0577559", "name": "mass", "pos": [ 42, 46 ] }
shock may arise due to a failure of preload ( hypovolaemic shock ) , myocardial contractility ( cardiogenic shock ) , afterload ( septic shock ) or combinations of these ( for example , anaphylactic shock , traumatic shock and neurogenic shock ) .
nichd_parent_of
{ "id": "C0036974", "name": "shock", "pos": [ 0, 5 ] }
{ "id": "C0036983", "name": "septic shock", "pos": [ 130, 142 ] }
cartilage degradation is a characteristic feature of various types of human arthritis , notably rheumatoid arthritis and osteoarthritis .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 76, 85 ] }
{ "id": "C0003873", "name": "rheumatoid arthritis", "pos": [ 96, 116 ] }