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from this preliminary experience on 34 patients in whom this procedure was indicated and then attempted under topical ( urethral instillation of 20 ml of 2 per cent lignocaine jelly ) or no anaesthesia , we are encouraged into believing that these patients may not require general or regional anaesthesia for this operation .
nichd_parent_of
{ "id": "C0002903", "name": "anaesthesia", "pos": [ 190, 201 ] }
{ "id": "C0002911", "name": "regional anaesthesia", "pos": [ 284, 304 ] }
two patients with carcinoma of the lung are described who presented with such a disorder but in whom there was no evidence of bone marrow fibrosis and in one of whom there was no evidence of bone marrow infiltration by tumor .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 80, 88 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 219, 224 ] }
this finding could reflect the effect of recent diagnosis and treatment of hypertension or be associated with the hypertensive state itself .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 5, 12 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 48, 57 ] }
after incorporation of labelled biomolecules in living systems , such as viruses , phages or cells , the radioactive decay of the label alters the biological behaviour of the system , in the extreme case causing loss of the ability to reproduce , the extent of these consequences depending strongly on the type of radioisotope .
nichd_parent_of
{ "id": "C0029235", "name": "living systems", "pos": [ 48, 62 ] }
{ "id": "C0042776", "name": "viruses", "pos": [ 73, 80 ] }
comments are presented suggesting that this metabolic mechanism may explain , in part , cartilage and bone resorption in areas of inflammation , such as arthritis , both rheumatoid arthritis and osteoarthritis .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 153, 162 ] }
{ "id": "C0003873", "name": "rheumatoid arthritis", "pos": [ 170, 190 ] }
the effect of two ca/p relations ( 2.1 y 4.5 ) in the diet on nutritive utilization of both minerals , egg production and egg characteristics ( weight , size , resistence and shell ca content ) was studied .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 126, 141 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 144, 150 ] }
xeromammographic examples of such diseases as congestive heart failure , diabetes mellitus , collagen vascular diseases , and endocrine diseases are presented and discussed .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 34, 42 ] }
{ "id": "C0014130", "name": "endocrine", "pos": [ 126, 135 ] }
a highly significant correlation was found between the presence of fibrinolytic degradation products ( fdp ) and the incidence of nephropathy and renal insufficiency , as well as between the presence of fibrin monomers ( godal 's ethanol-gelification test ) and the evolutive signs of the primary disease ( fever , accelerated esr ) .
nichd_parent_of
{ "id": "C0022658", "name": "nephropathy", "pos": [ 130, 141 ] }
{ "id": "C0035078", "name": "renal", "pos": [ 146, 151 ] }
the possible use of proline loading in high dosage for the detection of gh deficiency especially in small children and in infants is suggested .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 106, 114 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 122, 129 ] }
flowmetry performed before and after the procedure proved to be a very useful diagnostic tool , particularly in evaluating the immediate postoperative haemodynamic performance of the replaced aortic valve and the completeness of the correction .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 41, 50 ] }
{ "id": "C0220825", "name": "evaluating", "pos": [ 112, 122 ] }
the use of ct scanning is conjunction with other more invasive neuroradiological studies results in improved diagnosis and patient management in almost the entire spectrum of neurosurgical diseases -- subarachnoid hemorrhage due to aneurysm , stroke , trauma , normal pressure hydrocephalus , and especially neoplasms .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 189, 197 ] }
{ "id": "C0027651", "name": "neoplasms", "pos": [ 308, 317 ] }
the mean maternal age did not differ significantly from that of the general embryonic population , indicating that , although none of our cases were karyotyped , chromosome aberrations such as trisomies 13 and 18 that are closely associated with maternal age may not constitute a major part as causes of holoprosencephaly in human embryos .
nichd_parent_of
{ "id": "C0008625", "name": "chromosome aberrations", "pos": [ 162, 184 ] }
{ "id": "C0152095", "name": "trisomies 13", "pos": [ 193, 205 ] }
the most common diagnosis was infection , and organisms isolated included bacteria , fungi , pneumocystis carinii , and herpes simplex .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 46, 55 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 74, 82 ] }
the most common diagnosis was infection , and organisms isolated included bacteria , fungi , pneumocystis carinii , and herpes simplex .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 46, 55 ] }
{ "id": "C0016832", "name": "fungi", "pos": [ 85, 90 ] }
tumors showing both papillary and anaplastic structures ( papillary polymorphous cancers ) are considered to be the result of irregular tumor progression under which separate zones of neoplastic cells proved to be in different stages of differentiation .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 0, 6 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 81, 88 ] }
cross-reacting antigen ( cr-antigen ) previously found by indirect immunofluorescence in cell elements of murine multilayer epithelial cells ( except corneal epithelium ) to play the role of antigenic label of cover epithelia of ectodermal origin was found in mice tumor cells , related histogenetically with multilayer epithelium ( transplantable proventricular cancer , two strains of squamous-cell cervical cancer in mice ) .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 265, 270 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 410, 416 ] }
67 % of all lung diseases registrated belong to the obstructive syndrom , 6 % are bronchial carcinomas and 27 % represent the group of other chronic pulmonary diseases .
nichd_parent_of
{ "id": "C0024115", "name": "of", "pos": [ 5, 7 ] }
{ "id": "C0746102", "name": "chronic pulmonary diseases", "pos": [ 141, 167 ] }
it is demonstrated an after-treatment model for patients with myocardial infarction as a part of a complex project of electronic data processing within prevention and treatment of selected diseases of the heart and circulatory system ( electronic data processing project myocardial infarction ) .
nichd_parent_of
{ "id": "C0018799", "name": "of", "pos": [ 94, 96 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 271, 292 ] }
in physical examination , radiographic picture and at operation this tumor appeared suspicious of a malignant obstructive neoplasm , thus leading to the resection of the right colon and to ileocolic anastomosis .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 69, 74 ] }
{ "id": "C0006826", "name": "malignant", "pos": [ 100, 109 ] }
during a pertussis epidemic , the majority of children admitted with respiratory disease were under one year old and had pneumonia , with or without pertussis syndrome ;
nichd_parent_of
{ "id": "C0035204", "name": "respiratory", "pos": [ 69, 80 ] }
{ "id": "C0043167", "name": "pertussis", "pos": [ 149, 158 ] }
systematic control over the antimeasles immunity level with the aid of serological investigations is necessary for the purpose of detection of persons sensitive to measles in children 's collective bodies .
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 143, 150 ] }
{ "id": "C0008059", "name": "children 's", "pos": [ 175, 186 ] }
the detected changes in the indices of the ingestive and digestive function of neutrophils could be interpreted as a compensatory reaction of the organism in response to the action of chemical agents , whereas reduction of lysozyme content and the appearance in the microbial pattern of deep dermal layers of mannite-splitting and hemolytic froms of microbes pointed to the presence of the first unfavourable shifts in humoral and barrier immunity factors .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 146, 154 ] }
{ "id": "C0445623", "name": "microbes", "pos": [ 350, 358 ] }
a ventilator system which also in small children has a negligible compression volume was evaluated in a lung model and during repair of cleft lip and palate in 16 patients under general anaesthesia and in two other infants during other operations .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 40, 48 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 215, 222 ] }
in a double-blind crossover trial of two 12-week treatment periods with a 4-week treatment free interval , to which 21 patients were admitted , there was no statistically significant difference between clonidine 75 microgram twice daily and placebo in the total number of headache days , migraine indices , duration of attacks , number of severe attacks and consumption of acute attack treatment .
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 272, 280 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 288, 296 ] }
however , there was a marked reduction in number of headache days , migraine indices , duration of attacks and consumption of acute attack treatment during the second treatment period compared to the first treatment period , regardless of the treatment regime .
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 52, 60 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 68, 76 ] }
since such tumors have been found in half of reported cases and because extrathoracic lymphangiomas may coexist , lymphangiography with skeletal survey is recommended in all cases .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 11, 17 ] }
{ "id": "C0024221", "name": "lymphangiomas", "pos": [ 86, 99 ] }
however , ristocetin-induced platelet aggregation ( ripa ) with a final concentration 1.12 mg/ml was markedly abnormal-absent or virtually absent in 9 of 10 patients with sca , 3 of 3 patients with hemoglobin s-c disease , and 2 of 3 patients with sickle trait .
nichd_parent_of
{ "id": "C0002895", "name": "sca", "pos": [ 171, 174 ] }
{ "id": "C0019034", "name": "hemoglobin s-c", "pos": [ 198, 212 ] }
studies of an avirulent strain of ndv that replicated in the cns but produced no disease provided evidence that the histologic lesions and the neurologic disease were related to virus multiplication in the brain parenchyma .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 81, 88 ] }
{ "id": "C0027765", "name": "neurologic disease", "pos": [ 143, 161 ] }
a mechanism of the pathogenesis of ndv encephalitis is proposed and the disease is discussed relative to other paramyxovirus-induced encephalitic syndromes .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 72, 79 ] }
{ "id": "C0039082", "name": "syndromes", "pos": [ 146, 155 ] }
the existence of known heart disease often leads to heart failure which is difficult to treat .
nichd_parent_of
{ "id": "C0018799", "name": "the", "pos": [ 0, 3 ] }
{ "id": "C0018801", "name": "heart failure", "pos": [ 52, 65 ] }
coliform organisms were isolated from bedding , udders of cows exhibiting acute or chronic mastitis , and milk of cows tested for udder pathogens .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 9, 18 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 136, 145 ] }
an inflamed , but recognizable , solitary diverticulum of the caecum was treated by excision , but the tumour-like mass produced by the diverticulum was removed by resection .
nichd_parent_of
{ "id": "C0027651", "name": "tumour", "pos": [ 103, 109 ] }
{ "id": "C0577559", "name": "mass", "pos": [ 115, 119 ] }
the difference between the random and actual results are most pronounced for bone age , sitting height and the development of pubic hair and breasts , showing that these characteristics may indeed be critically related to menarche , while the same differences for weight , height , sitting height/height , and biacromial and bi-iliocristal diameters show that these latter are only moderately related to menarche .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 170, 185 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 264, 270 ] }
these findings , closely parallel to those we have previously reported in rats , suggest that the procedure is selectively sensitive to antidepressant treatments .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 98, 107 ] }
{ "id": "C0087111", "name": "treatments", "pos": [ 151, 161 ] }
[ the effect of cobalt on anemia caused by acetylphenylhydrazine . ii . research in rats with hypochromic anemia caused by milk ] .
nichd_parent_of
{ "id": "C0002871", "name": "anemia", "pos": [ 26, 32 ] }
{ "id": "C0002884", "name": "hypochromic anemia", "pos": [ 94, 112 ] }
[ spongiform encephalopathy ( connected to creutzfeld-jacob disease ) : biopsy studied by means of the electron microscope , confirmation by autopsy ] .
nichd_parent_of
{ "id": "C0162534", "name": "spongiform encephalopathy", "pos": [ 2, 27 ] }
{ "id": "C0022336", "name": "creutzfeld-jacob disease", "pos": [ 43, 67 ] }
in this procedure 500 to 600 c.c . of air is injected into the anterior mediastinal space by the supra- and retro-sternal ( or suband retro-xiphoid ) route .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 8, 17 ] }
{ "id": "C0013153", "name": "route", "pos": [ 150, 155 ] }
as part of its overall educational program , the american hospital association has since 1959 conducted three institutes on hospital librarianship to meet the demand for more competent librarians in medical , nursing school , and patients ' libraries .
nichd_parent_of
{ "id": "C0004927", "name": "conducted", "pos": [ 94, 103 ] }
{ "id": "C0006147", "name": "nursing", "pos": [ 209, 216 ] }
while the organism is highly pathogenic when introduced by way of the respiratory tract , it is innocuous when given subcutaneously even in large numbers .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 10, 18 ] }
{ "id": "C0450254", "name": "pathogenic", "pos": [ 29, 39 ] }
[ the influence of plasma upon the glucose uptake of erythrocytes in various diseases with glycosuria . iii . the influence of plasma upon the glucose uptake of erythrocytes in various endocrine disorders with glycosuria ] .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 77, 85 ] }
{ "id": "C0014130", "name": "endocrine disorders", "pos": [ 185, 204 ] }
the characteristic result of infection of the brain by this fungus was abscess formation , and this occurred in all except one of the cases reviewed .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 29, 38 ] }
{ "id": "C0000833", "name": "abscess", "pos": [ 71, 78 ] }
however , achievement of quantitative improvement in the accuracy of regulation of diabetes and moderation in deviations from the acceptable range of parameters were feasible .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 25, 37 ] }
{ "id": "C1514721", "name": "range", "pos": [ 141, 146 ] }
[ clinico-radiological findings of the adeno-broncho-parenchymal lesions of primary pulmonary tuberculous infection and its sequelae in childhood and adolescence ] .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 136, 145 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 150, 161 ] }
[ trial therapy of herpes recurrents by a vaccine prepared in cell culture and inactivated by ultraviolet rays . i. preparation of the vaccine and immunization trials in animals ] .
nichd_parent_of
{ "id": "C0042210", "name": "vaccine", "pos": [ 42, 49 ] }
{ "id": "C0042212", "name": "inactivated", "pos": [ 79, 90 ] }
newly isolated n. asteroides belonging to the acetamidase-positive group were shown to be always pathogenic , whereas the organisms of the acetamidase-negative group could be pathogenic and non-pathogenic in white mice .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 122, 131 ] }
{ "id": "C0450254", "name": "pathogenic", "pos": [ 194, 204 ] }
the newborns were evaluated the first and the fifth day of life with the brazelton neonatal behavioral assessment scale and with a modified prechtl neurological examination .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 18, 27 ] }
{ "id": "C0027853", "name": "neurological examination", "pos": [ 148, 172 ] }
both tumor and blood clot within the renal sinus appear as echogenic masses without a significant acoustic shadow .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 5, 10 ] }
{ "id": "C0577559", "name": "masses", "pos": [ 69, 75 ] }
conventional methods to determine the etiology of these pneumonias were unsuccessful but subsequent serological studies confirmed the diagnosis of legionnaires ' disease .
nichd_parent_of
{ "id": "C0032285", "name": "pneumonias", "pos": [ 56, 66 ] }
{ "id": "C0023241", "name": "legionnaires", "pos": [ 147, 159 ] }
the combined tumors and the numerous other similar neoplasms described in the literature and reviewed here suggest an endodermal origin for digestive and respiratory tract apud cells based on the hypothesis that cancer is a clonal proliferation , and mucous and squamous cell differentiation is an endodermal rather than neural crest characteristic .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasms", "pos": [ 51, 60 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 212, 218 ] }
the injuries included fractures , dislocations , fracture dislocations , and soft tissue injuries of the phalanges , metacarpals , carpals ( particularly the navicular ) , and distal radius/ulna , including intra-articular injuries .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 4, 12 ] }
{ "id": "C0016658", "name": "fractures", "pos": [ 22, 31 ] }
risk factor profiling , which synthesizes major risk factors into a composite score , is a beneficial procedure by which to evaluate individuals .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 102, 111 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 124, 132 ] }
we have found the doppler examination to be accurate in 92 % of limbs with suspected iliofemoral thrombosis and in 86 % of limbs with suspected calf vein thrombosis .
nichd_parent_of
{ "id": "C0040053", "name": "thrombosis", "pos": [ 97, 107 ] }
{ "id": "C0042487", "name": "vein", "pos": [ 149, 153 ] }
vaccine valency did not alter the serologic and challenge-exposure responses of chickens vaccinated with aiv a/turkey/wisconsin/68 , which was the virus component common to both monovalent and polyvalent vaccines .
nichd_parent_of
{ "id": "C0042210", "name": "vaccine", "pos": [ 0, 7 ] }
{ "id": "C1514218", "name": "polyvalent vaccines", "pos": [ 193, 212 ] }
a patient , aged 15 years and three months , with hypogonadism and anosmia ( kallman 's syndrome or maestre de san juan 's syndrome ) is presented .
nichd_parent_of
{ "id": "C0020619", "name": "hypogonadism", "pos": [ 50, 62 ] }
{ "id": "C0162809", "name": "kallman 's syndrome", "pos": [ 77, 96 ] }
clinical studies have shown parenteral bretylium to be effective in suppressing ventricular arrhythmias , particularly recurrent , drug resistant ventricular tachycardia or ventricular fibrillation .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 80, 103 ] }
{ "id": "C0042514", "name": "ventricular tachycardia", "pos": [ 146, 169 ] }
clinical studies have shown parenteral bretylium to be effective in suppressing ventricular arrhythmias , particularly recurrent , drug resistant ventricular tachycardia or ventricular fibrillation .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 80, 103 ] }
{ "id": "C0042510", "name": "ventricular", "pos": [ 173, 184 ] }
for at least three malignancies and tentatively a fourth ( breast and colon carcinoma , osteosarcoma , and melanoma ) , certain groups of patients have had longer disease-free survival produced by the use of chemotherapy after surgical removal of the primary lesion .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 19, 31 ] }
{ "id": "C0025202", "name": "melanoma", "pos": [ 107, 115 ] }
while the disease is considered benign , its similarity to more aggressive neoplasms can be both disturbing and misleading to the patient and the clinician .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 10, 17 ] }
{ "id": "C0027651", "name": "neoplasms", "pos": [ 75, 84 ] }
the new procedure is rapid , inexpensive and accurate , allowing for the detection of receptor in cytoplasm and/or nucleus and evaluation of receptor heterogeneity .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 8, 17 ] }
{ "id": "C0220825", "name": "evaluation", "pos": [ 127, 137 ] }
these patients formed a unique subset of patients with aplastic anemia in that they all had fanconi 's anemia , all demonstrated glucose intolerance following institution of androgen therapy , all had received androgen for at least 42 months prior to death , and all had coexistent benign liver cell tumors .
nichd_parent_of
{ "id": "C0002874", "name": "aplastic anemia", "pos": [ 55, 70 ] }
{ "id": "C0015625", "name": "fanconi 's anemia", "pos": [ 92, 109 ] }
after a complicated course , it was found that infection from appendicitis had extended to the body of the graft .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 47, 56 ] }
{ "id": "C0003615", "name": "appendicitis", "pos": [ 62, 74 ] }
results of comprehensive neurological examinations of 4 patients suffering from periodic disease have shown that the latter may be not only a disease entity , but also a syndrome characterizing some organic affections of the brain .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 89, 96 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 170, 178 ] }
this patient shows that atrial and ventricular arrhythmias can alternate and , since tachycardia with aberrant ventricular conduction can closely resemble ventricular tachycardia , intra-atrial electrocardiography may be necessary to establish an accurate diagnosis .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 35, 58 ] }
{ "id": "C0042514", "name": "ventricular tachycardia", "pos": [ 155, 178 ] }
the use of this clinical staging system , which is based on myeloma protein synthesis rates and the calculation of total body tumour cell mass , should be considered in planning future trials of therapy in this disease .
nichd_parent_of
{ "id": "C0027651", "name": "tumour", "pos": [ 126, 132 ] }
{ "id": "C0577559", "name": "mass", "pos": [ 138, 142 ] }
thirty-eight operations ( 32.8 per cent ) were performed in patients with mild or resolving stroke and 33 operations ( 45.9 per cent ) in patients with transient ischaemic attacks and/or amaurosis fugax .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 92, 98 ] }
{ "id": "C0007787", "name": "transient ischaemic attacks", "pos": [ 152, 179 ] }
the commonest errors arose because the international classification of diseases ( 8th edition ) stipulates that hydrops without mention of cause should be coded as hdn and because stillbirths to rhesus-negative mothers tend to be attributed to rhesus hdn automatically .
nichd_parent_of
{ "id": "C0014761", "name": "hdn", "pos": [ 164, 167 ] }
{ "id": "C0853694", "name": "rhesus hdn", "pos": [ 244, 254 ] }
though deaths from hdn may be overestimated in this way , they are also underestimated because rhesus disease , although mentioned on the certificate , is not selected as the underlying cause , which it may be .
nichd_parent_of
{ "id": "C0014761", "name": "hdn", "pos": [ 19, 22 ] }
{ "id": "C0853694", "name": "rhesus disease", "pos": [ 95, 109 ] }
if a local survey in the trent region reflected the pattern of medical outpatient practice nationally , then pounds 1.25 million could be saved annually if routine investigation was discontinued on all patients whose problem had already been diagnosed on the basis of the history and the clinical examination .
nichd_parent_of
{ "id": "C0220825", "name": "investigation", "pos": [ 164, 177 ] }
{ "id": "C0031809", "name": "clinical examination", "pos": [ 288, 308 ] }
the seasonal variation in the quarterly incidence of some sexually transmitted diseases and other conditions in scotland is compared with that of gonorrhoea and of conceptions leading to live births or abortions .
nichd_parent_of
{ "id": "C0036916", "name": "sexually transmitted", "pos": [ 58, 78 ] }
{ "id": "C0018081", "name": "gonorrhoea", "pos": [ 146, 156 ] }
in 812 patients who underwent routine preoperative electrocardiography a mean of 24.6 months after undergoing electrocardiography at the same institution , the frequency of new abnormalities was estimated to evaluate the cost-effectiveness of this procedure prior to an operation .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 248, 257 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 270, 279 ] }
in this paper we report the appearance of flat vesicle-containing endings in aldehyde-fixed ventral cochlear nucleus of rats with qualitative and quantitative properties suggesting they should be identified as calyceal processes .
nichd_parent_of
{ "id": "C0205556", "name": "qualitative", "pos": [ 130, 141 ] }
{ "id": "C0205396", "name": "identified", "pos": [ 196, 206 ] }
the minimum morphine concentration in plasma necessary to suppress the clinical signs of pain during surgery was found to be 65 ng/ml ( 95 % confidence limits of 46 to 83 ng/ml ) .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 71, 85 ] }
{ "id": "C0030193", "name": "pain", "pos": [ 89, 93 ] }
no difference was found in the minimum effective level of morphine when clinical signs of pain were observed by different anesthesiologists .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 72, 86 ] }
{ "id": "C0030193", "name": "pain", "pos": [ 90, 94 ] }
analysis of the five deaths suggested that , even in stage iii disease a surgical attempt should be made to remove the bulk of the tumour and that the abdominal radiotherapy dose should not be less than 3000 rad in 20 treatments in 28 days .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 63, 70 ] }
{ "id": "C0027651", "name": "tumour", "pos": [ 131, 137 ] }
however , the association of renal disease to extra-renal disorders , namely chronic active hepatitis and ulcerative colitis , or uveitis or the presence of an epithelioid granuloma with multinucleated giant cells suggests that in such patients an immunologic disorder might be responsible for the tubulo-interstitial nephritis .
nichd_parent_of
{ "id": "C0022658", "name": "renal disorders", "pos": [ 52, 67 ] }
{ "id": "C0041349", "name": "tubulo-interstitial nephritis", "pos": [ 298, 327 ] }
combined with the case history and auscultatory finding ( a continuous murmur on the right sternal edge ) , this may lead to the correct diagnosis by noninvasive means .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 48, 55 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 137, 146 ] }
the tat characteristics were independent of the level of adjustment at the time the tats were administered , not related to the child 's iq , socioeconomic status , race , or other family characteristics , and moderately negatively correlated with story length .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 8, 23 ] }
{ "id": "C1444754", "name": "length", "pos": [ 254, 260 ] }
they can be evaluated at different levels of sophistication using different parameters to describe physical chemical properties of the drugs and different mathematical methods .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 12, 21 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 99, 107 ] }
normal liver or liver with no pathognomonic changes of 77 cases ( 11.2 % ) , non-specific reactive hepatitis of 56 cases ( 8.0 % ) , viral hepatitis of 488 cases ( 71.0 % ) , alcoholic hepatitis of 25 cases ( 3.6 % ) , fatty liver of 23 cases ( 3.3 % ) , massive liver necrosis of 3 cases , liver fibrosis of 2 cases , congestive liver of 1 case , and unclassified 12 cases due to inadequate specimens or other reasons .
nichd_parent_of
{ "id": "C0019158", "name": "non-specific", "pos": [ 77, 89 ] }
{ "id": "C0042721", "name": "viral hepatitis", "pos": [ 133, 148 ] }
it was considered that the cop test was a useful diagnostic method for schistosomiasis japonica and the sensitivity and efficiency of this test were superior to those of intradermal test with regarded to the screening of the subjects for fecal examination .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic method", "pos": [ 49, 66 ] }
{ "id": "C0022885", "name": "test", "pos": [ 182, 186 ] }
lung sections from 33 infants who died suddenly and unexpectedly and were diagnosed by medical examiners as sudden infant death syndrome ( sids ) gave evidence of bound immunoglobulin g ( igg ) when examined by direct fluorescent antibody technique .
nichd_parent_of
{ "id": "C0011065", "name": "died", "pos": [ 34, 38 ] }
{ "id": "C0038644", "name": "sudden infant death syndrome", "pos": [ 108, 136 ] }
methods of intervention thus far employed generally have not been evaluated in any systematic fashion .
nichd_parent_of
{ "id": "C0184661", "name": "methods", "pos": [ 0, 7 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 66, 75 ] }
persistent immunocomplexaemia induced by administration of the antigen over 60 and 100 days , respectively , resulted in mesangioproliferative glomerulonephritis in 7 , in membranoproliferative glomerulonephritis in 3 , and in membraneous glomerulonephritis in 1 out of 11 laboratory animals .
nichd_parent_of
{ "id": "C0017658", "name": "glomerulonephritis", "pos": [ 143, 161 ] }
{ "id": "C0017662", "name": "membranoproliferative glomerulonephritis", "pos": [ 172, 212 ] }
persistent immunocomplexaemia induced by administration of the antigen over 60 and 100 days , respectively , resulted in mesangioproliferative glomerulonephritis in 7 , in membranoproliferative glomerulonephritis in 3 , and in membraneous glomerulonephritis in 1 out of 11 laboratory animals .
nichd_parent_of
{ "id": "C0017658", "name": "glomerulonephritis", "pos": [ 143, 161 ] }
{ "id": "C0017665", "name": "membraneous", "pos": [ 227, 238 ] }
in this study , thoracic gas volume ( tgv ) has been measured directly by occlusion plethysmography in six normal babies during behavioral quiet and active sleep and related to the different movements of the rib cage and abdomen-diaphragm that occur during each sleep state .
nichd_parent_of
{ "id": "C0004927", "name": "behavioral", "pos": [ 128, 138 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 262, 267 ] }
the results suggest that the study 's goals were achieved and that the nonaversive combined procedure could be used to treat not only habitual smokers but also smokers with severe cardiovascular and respiratory problems , because it does not have some of the inherent limitations of the successful aversive smoking cessation procedures .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 92, 101 ] }
{ "id": "C0087111", "name": "treat", "pos": [ 119, 124 ] }
the finding that ribosomes from thiostrepton-resistant mutants do not contain protein l11 suggests that l11 not only is involved in binding of thiostrepton , but also , when mutationally altered , confers resistance to this antibiotic .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 4, 11 ] }
{ "id": "C0949285", "name": "resistance", "pos": [ 205, 215 ] }
a female patient presented at the end of a holiday cruise with the pneumonitis of legionnaires ' disease .
nichd_parent_of
{ "id": "C0032285", "name": "pneumonitis", "pos": [ 67, 78 ] }
{ "id": "C0023241", "name": "legionnaires", "pos": [ 82, 94 ] }
the potential of ultrasound to provide local tumor control and to enhance other therapy modes has motivated the current efforts by several groups to further study and understand it actions on malignancies .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 45, 50 ] }
{ "id": "C0006826", "name": "malignancies", "pos": [ 192, 204 ] }
dentists must evaluate the patient 's objectives in relation to the physical criteria for treatment and should not compromise standards of care to accommodate the patient 's demands .
nichd_parent_of
{ "id": "C0220825", "name": "evaluate", "pos": [ 14, 22 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 68, 76 ] }
at autopsy , severe aortic atherosclerosis was observed and atheroembolic renal disease was confirmed as the cause of renal failure .
nichd_parent_of
{ "id": "C0022658", "name": "renal", "pos": [ 74, 79 ] }
{ "id": "C0035078", "name": "renal failure", "pos": [ 118, 131 ] }
excessive adult mortality with a high incidence of tumors , mainly hemangiomas , is associated with this gene -- at least extending over a two-generation observation interval .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 51, 57 ] }
{ "id": "C0018916", "name": "hemangiomas", "pos": [ 67, 78 ] }
although the initial mouse with this disease had 200,000 lambda-bearing b lymphocytes per mm3 in the peripheral blood and closely resembled a human chronic lymphocytic leukemia patient , the studies described suggest that this murine b cell neoplasm is a lymphoma with a striking predilection for splenic involvement .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 37, 44 ] }
{ "id": "C0027651", "name": "neoplasm", "pos": [ 241, 249 ] }
this procedure eliminates the use of the hazardous cyanogen bromide activation process and is potentially suitable for use in both direct systems for evaluation of specificity and potency of fluorescent conjugates and in indirect systems for serological screening of sera for specific antibody .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 5, 14 ] }
{ "id": "C0220825", "name": "evaluation", "pos": [ 150, 160 ] }
this methodology , when applied to the study of dermatoses in which abnormalities of cutaneous nerve terminals are suspected , should furnish precise functional pathophysiological details .
nichd_parent_of
{ "id": "C0037274", "name": "dermatoses", "pos": [ 48, 58 ] }
{ "id": "C0037268", "name": "abnormalities of cutaneous", "pos": [ 68, 94 ] }
in control group children all three substrates were hydrolysed at similar rates , and these were significantly lower than in infants with hypertrophic pyloric stenosis .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 17, 25 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 125, 132 ] }
in the case of posterior tumors , the patient exhibits a mass which is usually mistaken for a pilonidal cyst .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 25, 31 ] }
{ "id": "C0577559", "name": "mass", "pos": [ 57, 61 ] }
certain common features in the cases in which there are no post mortem changes to explain death ( typical cot deaths ) are described and compared with cases with an acceptable cause of death and with control cases .
nichd_parent_of
{ "id": "C0011065", "name": "death", "pos": [ 90, 95 ] }
{ "id": "C0038644", "name": "cot deaths", "pos": [ 106, 116 ] }
the mean age of onset and time between first feeding and onset of nec was similar among the three groups .
nichd_parent_of
{ "id": "C0040223", "name": "time", "pos": [ 26, 30 ] }
{ "id": "C2911686", "name": "first", "pos": [ 39, 44 ] }
statistical evaluation of the results with plasma samples from 47 patients with colorectal carcinomas and from 7 patients with other gastrointestinal disorders ( polyps , villous papilloma , diverticulitis , and crohn 's disease ) indicated that a significant number of patients had antibodies to cross-reactive tumor antigen ( s ) .
nichd_parent_of
{ "id": "C0017178", "name": "gastrointestinal disorders", "pos": [ 133, 159 ] }
{ "id": "C0010346", "name": "crohn 's disease", "pos": [ 212, 228 ] }