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the data suggest that results of tests with the use of tumor-unrelated parameters of immune responsiveness for the assessment of the immune status of cancer patients should be interpreted with caution .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 55, 60 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 150, 156 ] }
microsomal and thyroglobulin autoantibody activity has been detected in synovial fluid from 34 of 50 patients with various arthritides ( rheumatoid arthritis , ankylosing spondylitis , osteoarthrosis , and gout ) .
nichd_parent_of
{ "id": "C0003864", "name": "arthritides", "pos": [ 123, 134 ] }
{ "id": "C0003873", "name": "rheumatoid arthritis", "pos": [ 137, 157 ] }
cold pressor test in detection of coronary heart-disease and cardiomyopathy using technetium-99m gated blood-pool imaging .
nichd_parent_of
{ "id": "C0018799", "name": "of", "pos": [ 31, 33 ] }
{ "id": "C0878544", "name": "cardiomyopathy", "pos": [ 61, 75 ] }
the differences in diagnostic sensitivities of the tests for resectable and non-resectable disease are probably due to variations in pathological features which influence not only the stage of presentation , but also the detectability of the tumour .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 91, 98 ] }
{ "id": "C0027651", "name": "tumour", "pos": [ 242, 248 ] }
in women with a discrete mass requiring biopsy , mammography combined with clinical findings predicted with 100 % confidence over half the cancers diagnosed .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 75, 92 ] }
{ "id": "C0011900", "name": "diagnosed", "pos": [ 147, 156 ] }
this disorder might be a late endocrine defect due to the basic metabolic disturbance of the disease .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 5, 13 ] }
{ "id": "C0014130", "name": "endocrine", "pos": [ 30, 39 ] }
the authors report on their experiences gained during follow-up studies in 3 children , who as neonates had had renal venous thrombosis , and had been treated with heparin .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 77, 85 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 95, 103 ] }
spermatogenic characteristics of rb4/+ mice , such as testis weight , sperm production and the number of diplotene-metaphase-i figures found in stage xii of the seminiferous epithelium , suggest delay and cell death during this period .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 14, 29 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 61, 67 ] }
the present case concerns a child of 8 years in whom the finding of hemiplegia led to a diagnosis of intracranial fibrodysplasia which was proven by arteriography and biopsy .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 57, 64 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 88, 97 ] }
this previously unreported clinical finding contrasts with the impairment of tendon reflexes in the limbs and should not rule out the diagnosis of friedreich ataxia .
nichd_parent_of
{ "id": "C0037088", "name": "clinical finding", "pos": [ 27, 43 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 134, 143 ] }
subdivisions of the neoplastic population according to hormonal status and parity led to the emergence of significant differences : frequency of a28 in menopausal nulliparous women with breast cancer is 26 vs .
nichd_parent_of
{ "id": "C0030563", "name": "parity", "pos": [ 75, 81 ] }
{ "id": "C0425979", "name": "nulliparous", "pos": [ 163, 174 ] }
a review of infections with mycoplasma pneumoniae in children , emphasizing their frequency , association with viral infections , nonspecific clinical aspects , diagnostic data , and extrapulmonary possible manifestations is presented .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 12, 22 ] }
{ "id": "C0042769", "name": "viral infections", "pos": [ 111, 127 ] }
pneumonia produced by the group y organism may mimic disease caused by common respiratory tract pathogens , and isolation by routine methods may be difficult .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 34, 42 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 96, 105 ] }
in the evaluation of male and female infertility the history , family history , physical examination , and endocrine and gonadal functional evaluations are the most informative measures .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 7, 17 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 80, 100 ] }
every organism isolated from such a patient must be considered a potential enemy , regardless of its pathogenic reputation , and evidence of infection must be sought .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 6, 14 ] }
{ "id": "C0450254", "name": "pathogenic", "pos": [ 101, 111 ] }
following a single infection most animals eliminated the organisms before the appearance of clinical signs , but one retained the bacteria for four days .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 57, 66 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 130, 138 ] }
in the present investigation , the functional significance of different levels of postoperative serum ck-mb activity was studied in 21 patients by clinical re-examination , including exercise test , after 18 months .
nichd_parent_of
{ "id": "C0220825", "name": "investigation", "pos": [ 15, 28 ] }
{ "id": "C0031809", "name": "clinical", "pos": [ 147, 155 ] }
rats developed unusual malignant neoplasms , such as kupffer cell sarcomas of the liver and sarcomas of the mammary gland , uterus , and stomach .
nichd_parent_of
{ "id": "C0006826", "name": "malignant", "pos": [ 23, 32 ] }
{ "id": "C1261473", "name": "sarcomas", "pos": [ 92, 100 ] }
amongst our 60 cases of crohn 's disease of the colon or of the ileon and colon , articular manifestations were the most frequent : arthralgias 25 cases ( 42 % ) , true arthritis 17 cases ( 28 % ) , spondylarthritis 5 cases , aacro-ileitis 9 cas ( 13 % ) , finger hippocratism 11 cases ( 18 % ) .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 169, 178 ] }
{ "id": "C0949690", "name": "spondylarthritis", "pos": [ 199, 215 ] }
beside the principal aspects of cysticercosis ( see the first part of this article ) there are others clinical forms : medullar , ocular , subcutaneous , often associated to cerebral cysticercosis , latent or not .
nichd_parent_of
{ "id": "C0010678", "name": "cysticercosis", "pos": [ 32, 45 ] }
{ "id": "C0338437", "name": "cerebral cysticercosis", "pos": [ 174, 196 ] }
the initial tumor was on the posterior wall of rectum , but was necrosed : bone metastasing chemodectoma , or locally invading carcinoid ? this new complex paraneoplastic disease seems to be associated with apud tumor .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 171, 178 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 212, 217 ] }
the possible complications to parent and fetus are discussed , including the complications of pregnancy and immunosuppressive drug therapy .
nichd_parent_of
{ "id": "C0009566", "name": "complications", "pos": [ 13, 26 ] }
{ "id": "C0032962", "name": "complications of pregnancy", "pos": [ 77, 103 ] }
diagnostic exploratory celiotomy as the primary procedure in the trauma patient is rarely indicated since the validation of peritoneal lavage as a diagnostic technic .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 48, 57 ] }
{ "id": "C0430022", "name": "diagnostic", "pos": [ 147, 157 ] }
anesthetic management is reviewed , and emphasis is placed on careful evaluation of the patient 's airway , using physical and roentgenographic examination to plan adequate airway management .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 70, 80 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 114, 122 ] }
there was significant improvement in 'ripeness ' of the cervix in all groups , the intravaginal route giving slightly better results than the oral route .
nichd_parent_of
{ "id": "C0013153", "name": "route", "pos": [ 96, 101 ] }
{ "id": "C1527415", "name": "oral route", "pos": [ 142, 152 ] }
the authors have developed a procedure to evaluate the performance of cerebral aneurysm clips as a function of intravascular pressure and aneurysm neck diameter .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 29, 38 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 42, 50 ] }
this finding , the lack of evidence of hospital outbreaks and the presence of comparable prevalences in all age groups suggest that lv infections occur on a continuing basis in this population .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 5, 12 ] }
{ "id": "C3714514", "name": "infections", "pos": [ 135, 145 ] }
apart from the classical professional diseases silicosis and asbestosis unspecific diseases of the respiratory organ , carcinomas and allergoses come into the foreground of interest .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 38, 46 ] }
{ "id": "C0035204", "name": "diseases", "pos": [ 83, 91 ] }
the development of malignant tumors was accompanied by the colonization of the pulmonary ways by a variety of organisms , including bacteria of the fecal flora .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 110, 119 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 132, 140 ] }
the immunogenicity of 2 meningococcal vaccines , multicomponent vaccine produced at the mechnikov research institute for vaccines and sera in moscow and polysaccharide vaccine obtained from merck sharp & dohme ( usa ) , was evaluated on experimental meningococcal sepsis in mice , produced by the injection of meningococcal culture in mucin suspension .
nichd_parent_of
{ "id": "C0042210", "name": "vaccines", "pos": [ 38, 46 ] }
{ "id": "C3273243", "name": "polysaccharide vaccine", "pos": [ 153, 175 ] }
the protective effect of these 2 vaccines , expressed in terms of ed50 , was 0.28 +/- 0.12 for the multicomponent vaccine and 0.25 +/- 0.24 for the polysaccharide vaccine ;
nichd_parent_of
{ "id": "C0042210", "name": "vaccine", "pos": [ 33, 40 ] }
{ "id": "C3273243", "name": "polysaccharide vaccine", "pos": [ 148, 170 ] }
the procedure uses the fallopian canal as a route by which to approach the cochlear potentials ' generators , while leaving the middle ear untouched .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0013153", "name": "route", "pos": [ 44, 49 ] }
parental contact was estimated for three different periods : 1 ) childhood , 2 ) adolescence , 3 ) the year before investigation .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 65, 74 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 81, 92 ] }
the procedure for skilled clinical observation of function in cardiac patients is described and data are presented from the use of this procedure to evaluate early subacute and high-risk cardiac patients during self-care in an acute hospital .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 149, 157 ] }
the fit-test method for powered air-purifying respirators described here allowed quantitative determination of the leakage of paprs that offered pfs ranging from 50 to greater than 10,000 .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 81, 93 ] }
{ "id": "C1514721", "name": "ranging", "pos": [ 149, 156 ] }
clinical findings included the development and progression of cirrhosis of the liver , bronzing of the skin , and diabetes mellitus , all consistent with a diagnosis of hemochromatosis .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 0, 17 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 156, 165 ] }
other features included k+ contracture , staircase effect , poor extensibility , length-tension relationship with a peak tensile response at 115 -- 120 % of the resting length , and requirement of ca2+ .
nichd_parent_of
{ "id": "C1521970", "name": "features", "pos": [ 6, 14 ] }
{ "id": "C1444754", "name": "length", "pos": [ 169, 175 ] }
in two patients with thyroiditis caused by coccidioides immitis , presented thyroid symptoms and findings were characteristic of subacute thyroiditis .
nichd_parent_of
{ "id": "C0040147", "name": "thyroiditis", "pos": [ 21, 32 ] }
{ "id": "C0040149", "name": "subacute thyroiditis", "pos": [ 129, 149 ] }
most children infected with rotavirus were under 2 years of age , but dehydration was most severe in infants aged between 12 and 18 months .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 5, 13 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 101, 108 ] }
a good correlation between results by the bht and by the ordinary lactose tolerance test was obtained after oral administration of 2 g/kg lactose to 21 healthy infants and children , 2 congenital lactase-deficient infants , and 7 adults .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 172, 180 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 214, 221 ] }
a report is given on 40 spinal cord tumours in children and infants , the diagnosis of which was considerably delayed in part .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 47, 55 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 60, 67 ] }
the disease develops with a clinical picture typical for systemic vasculitis , with joint-pain , skin-rash and grave abdominal syndrome , being the reason for unnecessary surgical intervention .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 4, 11 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 127, 135 ] }
the renal changes originate even at the very beginning of the disease and are clinically characterized , besides the exceptionally quick evolution , by the picture of acute renal insufficiency with progressing azotemia , severe electrolyte disturbances and anemic syndrome and pathomorphologically by the picture of severe diffuse intra- and extracapillary proliferative glomerulitis .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 62, 69 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 264, 272 ] }
in two cases of open neural tube defect , one of anencephaly and another of spina bifida , human amniotic fluid also had a strongly depressing effect on the experimental oedema provoked by serotonin .
nichd_parent_of
{ "id": "C0027794", "name": "neural tube defect", "pos": [ 21, 39 ] }
{ "id": "C0080178", "name": "spina bifida", "pos": [ 76, 88 ] }
there were 700 plasma samples from women with normal prenancies and 60 from women with pregnancies complicated by fetal ntds ( 30 with anencephaly and 30 with spina bifida ) .
nichd_parent_of
{ "id": "C0027794", "name": "ntds", "pos": [ 120, 124 ] }
{ "id": "C0080178", "name": "spina bifida", "pos": [ 159, 171 ] }
( 3 ) elicitor preparations from cell walls of phytophthora megasperma var . sojae , a fungal pathogen of soybean , and botrytis cinerea , the common grey mould , were much less effective than the c. lindemuthianum wall-released elicitor .
nichd_parent_of
{ "id": "C0016832", "name": "fungal", "pos": [ 87, 93 ] }
{ "id": "C0369241", "name": "mould", "pos": [ 155, 160 ] }
this paper presents evidence for my hypothesis that the diverse features of a migraine attack , both during the prodromal and the headache phases , become explicable if migraine is caused by a primary abnormality of platelet behaviour .
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 130, 138 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 169, 177 ] }
no severe infections occurred in the granulocyte transfusion group while three fungal infections occurred in the controls .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 10, 20 ] }
{ "id": "C0026946", "name": "fungal infections", "pos": [ 79, 96 ] }
we report a procedure for the purification of chilo iridescent virus ( iridovirus type 6 ) , an evaluation of the purification procedure , and the results of analyses of the virion proteins by acrylamide gel electrophoresis .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 12, 21 ] }
{ "id": "C0220825", "name": "evaluation", "pos": [ 96, 106 ] }
t-cell malignancies included lymphoblastic lymphomas ( 3 cases ) , large cell ( `` '' histiocytic '' '' ) lymphomas ( 4 cases ) , lymphoepithelioid cell ( `` '' lennert 's '' '' ) lymphomas ( 2 cases ) , mycosis fungoides ( 3 cases ) and diffuse poorly differentiated lymphocytic lymphomas ( 2 cases ) .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 7, 19 ] }
{ "id": "C0024299", "name": ") lymphom", "pos": [ 178, 187 ] }
in order to assess the influence of an inherited blood coagulation disorder in individuals who developed cancer , a mail survey of physicians who care for individuals with a bleeding diathesis was evaluated .
nichd_parent_of
{ "id": "C0018939", "name": "the", "pos": [ 19, 22 ] }
{ "id": "C0005779", "name": "bleeding diathesis", "pos": [ 174, 192 ] }
in contrast , serial plasma cea values correlated positively with clinical disease status in only 28 % of patients whose tumors were devoid of cea .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 75, 82 ] }
{ "id": "C0027651", "name": "tumors", "pos": [ 121, 127 ] }
in tumor-bearing animals not treated with clofibrate , cancer growth was associated with elevated rates of fibrinogen synthesis and a doubling of plasma fibrinogen concentrations .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 3, 8 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 55, 61 ] }
whether they were growing alone or in the presence of a second focus , tumor growth rates were similar until the combined mass of multiple tumors approached that which was incompatible with survival .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 71, 76 ] }
{ "id": "C0577559", "name": "mass", "pos": [ 122, 126 ] }
continuation or cessation of retinoid treatment in 60-day tumor-bearing rats had no effect on the time of appearance of additional cancers .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 58, 63 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 131, 138 ] }
the cessation of retinoid treatment in 60-day tumor-free rats resulted in a rapid increase in the appearance of cancers ;
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 46, 51 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 112, 119 ] }
to determine whether the hauser procedure for recurrent dislocation of the patella prevents repeated dislocation and provides a functional knee without late degenerative arthritis , 52 patients with 67 surgically treated knees were studied clinically and roentgenographically with an average follow-up of 17.1 years .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 32, 41 ] }
{ "id": "C0543467", "name": "surgically", "pos": [ 202, 212 ] }
twenty-five postoperative lumbar laminectomy and diskectomy patients were administered the mmpi and evaluated by physical examination which included the burns ' bench test .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 100, 109 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 113, 133 ] }
advancing age and previous venous thrombosis served as predictors for pulmonary embolism and thrombophlebitis , respectively ( p less than 0.01 ) , but obesity , venous varicosities , diabetes mellitus , cigarette smoking , previous pulmonary embolism , and length of surgery did not , for either .
nichd_parent_of
{ "id": "C0042487", "name": "venous thrombosis", "pos": [ 27, 44 ] }
{ "id": "C0040046", "name": "thrombophlebitis", "pos": [ 93, 109 ] }
the data suggest that pulmonary hypertension is common in patients with long-standing poorly controlled systemic hypertension , and that minoxidil , in doses sufficient to significantly reduce systemic blood pressure , does not cause or aggravate pulmonary hypertension .
nichd_parent_of
{ "id": "C0020538", "name": "systemic", "pos": [ 104, 112 ] }
{ "id": "C0020542", "name": "pulmonary hypertension", "pos": [ 247, 269 ] }
the absence of afp elevation in 3 other cases of pure germinoma ( atypical teratoma ; pinealoma ) agrees with reports which describe that , in the germ cell tumor of the gonads , a rise in afp is not observed in pure seminoma but is found in embryonal carcinoma and endodermal sinus tumor ( yolk sac tumor ) .
nichd_parent_of
{ "id": "C0205851", "name": "the germ cell tumor of", "pos": [ 143, 165 ] }
{ "id": "C0036631", "name": "pure seminoma", "pos": [ 212, 225 ] }
the complications considered are : glaucoma , marginal infiltrations , epithelial defects suture infections , wound dehiscence , disturbances of the tear-film and recurrent herpes .
nichd_parent_of
{ "id": "C0009566", "name": "complications", "pos": [ 4, 17 ] }
{ "id": "C0259768", "name": "wound dehiscence", "pos": [ 110, 126 ] }
no abnormalities were detected in the following syndromes : achondroplasia , diastrophic dwarfism , thanatophoric dwarfism , jeune disease , spondyloepiphyseal dysplasia congenita , kozlowski syndrome , osteogenesis imperfecta , polyepiphyseal dysplasia with diabetes mellitus .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 131, 138 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 192, 200 ] }
two groups of patients who had a stroke , prolonged reversible ischaemic neurological deficit or transient ischaemic attacks were compared ;
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 33, 39 ] }
{ "id": "C0007787", "name": "transient ischaemic attacks", "pos": [ 97, 124 ] }
of them , 9 fetuses ( 1.7 % ) showed external and visceral abnormalities such as hydrocephalia ( 5 cases ) , short tail ( 2 ) , anophthalmia ( 1 ) and talipomanus flexa ( 1 ) .
nichd_parent_of
{ "id": "C0000768", "name": "abnormalities", "pos": [ 59, 72 ] }
{ "id": "C0003119", "name": "anophthalmia", "pos": [ 128, 140 ] }
on analysis of the sonar and post abortion findings it was found , that the aborted pregnancies fell into 3 clearly defined groups : blighted ova , missed abortions and hydatidiform moles .
nichd_parent_of
{ "id": "C0156543", "name": "abortion findings", "pos": [ 34, 51 ] }
{ "id": "C0000814", "name": "missed abortions", "pos": [ 148, 164 ] }
human leukaemia-associated antigens expressed by acute myelocytic leukaemia cells and their detection by heterologous antisera .
nichd_parent_of
{ "id": "C0023418", "name": "associated", "pos": [ 16, 26 ] }
{ "id": "C0023467", "name": "acute myelocytic leukaemia", "pos": [ 49, 75 ] }
human leukaemia-associated antigens expressed by acute lymphocytic leukaemias and their detection with heterologous antisera to t , b- , and non-t-non-b subtype al blasts .
nichd_parent_of
{ "id": "C0023418", "name": "associated", "pos": [ 16, 26 ] }
{ "id": "C0023449", "name": "acute lymphocytic leukaemias", "pos": [ 49, 77 ] }
antisera from rabbits and goats against subtypes of acute lymphocytic leukaemia ( all with t-cell markers , all with b-cell markers , non-t-non-b all ) were tested for their specificity in complement-dependent in-vitro cytotoxicity testing .
nichd_parent_of
{ "id": "C0023449", "name": "acute lymphocytic leukaemia", "pos": [ 52, 79 ] }
{ "id": "C1961099", "name": "all", "pos": [ 146, 149 ] }
the seizures were controlled for at least three years in 22.9 % of the cases with partial seizure and in 63.3 % of the cases with generalized seizure .
nichd_parent_of
{ "id": "C0036572", "name": "seizures", "pos": [ 4, 12 ] }
{ "id": "C0751495", "name": "partial seizure", "pos": [ 82, 97 ] }
inflammatory stress as characterized by infection with streptococcus pneumoniae , administration of endotoxin , or the induction of a turpentine abscess is characterized by the inhibition of the ketosis assoicated with fasting and a decline in the level of free fatty acids in the plasma .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 40, 49 ] }
{ "id": "C0000833", "name": "abscess", "pos": [ 145, 152 ] }
excretion of sisomicin in the urine is lower in children than in adults , amounting within 24 hours to only 10 -- 20 % in newborns , and 30 -- 40 % in school-children .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 48, 56 ] }
{ "id": "C0021289", "name": "newborns", "pos": [ 122, 130 ] }
are poor living conditions in childhood and adolescence and important risk factor for arteriosclerotic heart disease ?
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 30, 39 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 44, 55 ] }
effect of estradiol and progesterone on the susceptibility of mice to bacterial infection , with special regard to pyelonephritis .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial", "pos": [ 70, 79 ] }
{ "id": "C0034186", "name": "pyelonephritis", "pos": [ 115, 129 ] }
although a number of maternal viral diseases have been etiologically incriminated in congenital defects , only two-rubella and cytomegalovirus infection-are definitely proved to be associated with anomalies or mental retardation in infants .
nichd_parent_of
{ "id": "C0042769", "name": "viral diseases", "pos": [ 30, 44 ] }
{ "id": "C0035920", "name": "rubella", "pos": [ 115, 122 ] }
chromosomal abnormalities in human diploid cells infected with mycoplasma and their possible relevance to the aetiology of down 's syndrome ( mongolism ) .
nichd_parent_of
{ "id": "C0008625", "name": "chromosomal abnormalities", "pos": [ 0, 25 ] }
{ "id": "C0013080", "name": "mongolism", "pos": [ 142, 151 ] }
[ electropolygraphic and behavioral study of waking states and sleep in the guinea pig ( cavia porcellus ) ] .
nichd_parent_of
{ "id": "C0004927", "name": "behavioral", "pos": [ 25, 35 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 63, 68 ] }
[ theory of a new uniformly organized system of care , education and rearing during infancy , childhood and adolescence ] .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 94, 103 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 108, 119 ] }
evaluation of phonocardiography in congenital heart diseases : with special reference to the influence of the double stenosis of the right ventricular outflow tract on the systolic murmurs in tetralogy of fallot .
nichd_parent_of
{ "id": "C0152021", "name": "congenital heart diseases", "pos": [ 35, 60 ] }
{ "id": "C0039685", "name": "tetralogy of fallot", "pos": [ 192, 211 ] }
examination and control of phlebothrombosis , thrombophlebitis and thromboembolic conditions with szirmai 's angio-myograph and their treatment with `` '' hah '' '' .
nichd_parent_of
{ "id": "C0042487", "name": "phlebothrombosis", "pos": [ 27, 43 ] }
{ "id": "C0040046", "name": "thrombophlebitis", "pos": [ 46, 62 ] }
[ effect of the stimulus of different temperatures on automatic reflexes of infants ' legs ( the placing reflex and the grasping reflex ) ] .
nichd_parent_of
{ "id": "C2825497", "name": "reflexes", "pos": [ 64, 72 ] }
{ "id": "C0234175", "name": "grasping reflex", "pos": [ 120, 135 ] }
an unusual form of congenital heart disease : patent ductus arteriosus associated with coarctation of the aorta ;
nichd_parent_of
{ "id": "C0152021", "name": "of congenital heart disease", "pos": [ 16, 43 ] }
{ "id": "C0013274", "name": "patent ductus arteriosus", "pos": [ 46, 70 ] }
well defined indications for adenotonsillectomy include frequent occurrence of infection , peritonsillar abscess , cervical lymph node disease believed caused by tonsillar infection , otitis media , and hypertrophy sufficient to embarrass swallowing or breathing .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 135, 142 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 172, 181 ] }
[ investigations on conditions of plasma proteins in the evaluation of the risk of cardiopathy in life insurance with special reference to the rheumatic cardiopathies ] .
nichd_parent_of
{ "id": "C0018799", "name": "cardiopathy", "pos": [ 83, 94 ] }
{ "id": "C0035439", "name": "rheumatic", "pos": [ 143, 152 ] }
[ comparative studies on the behavior of pas and isonicotinic acid hydrazide during gestation and lactation in the experimental animal ] .
nichd_parent_of
{ "id": "C0004927", "name": "behavior", "pos": [ 29, 37 ] }
{ "id": "C0006147", "name": "lactation", "pos": [ 98, 107 ] }
[ significance of streptomycin in the treatment of tuberculosis in children ; streptomycin in pulmonary tuberculosis in infants ] .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 67, 75 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 120, 127 ] }
[ dangerous drug allergies . i. urticaria gigantea of the serum sickness type due to penicillin ; differential diagnosis to wasp sting allergy ] .
nichd_parent_of
{ "id": "C0020517", "name": "allergies", "pos": [ 17, 26 ] }
{ "id": "C0036830", "name": "serum sickness", "pos": [ 58, 72 ] }
tests in which organisms containing `` '' nuclear '' '' antigens for ifa detection of antibodies to these organisms are used may result in `` '' false-positives '' '' with sera containing antinuclear antibodies .
nichd_parent_of
{ "id": "C0003241", "name": "f antibodi", "pos": [ 84, 94 ] }
{ "id": "C0003243", "name": "antinuclear antibo", "pos": [ 188, 206 ] }
[ diagnostic and therapeutic value of a simple technic of hyperoxia in cardiac resuscitation ( 25 cases ) ] .
nichd_parent_of
{ "id": "C0087111", "name": "therapeutic", "pos": [ 17, 28 ] }
{ "id": "C2981152", "name": "cardiac", "pos": [ 71, 78 ] }
the concentration of prolactin in the serum of normal children and adults of either sex was usually below 30 ng/ml , while very high concentrations ( up to 500 ng/ml ) were observed in newborn infants .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 54, 62 ] }
{ "id": "C0021289", "name": "newborn infants", "pos": [ 185, 200 ] }
in the hypothyroid group , the range was similar in patients with both primary and secondary hypothyroidism .
nichd_parent_of
{ "id": "C0020676", "name": "hypothyroid", "pos": [ 7, 18 ] }
{ "id": "C3665349", "name": "secondary", "pos": [ 83, 92 ] }
electrophoretic studies of sodium dodecyl sulfate-disrupted b3 virus in sodium dodecyl sulfate-polyacrylamide gels revealed four radioactive virus polypeptides ( vp 1 to 4 ) , of which the three largest migrated slightly faster than their poliovirus t1 counterparts .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 63, 68 ] }
{ "id": "C0206435", "name": "poliovirus", "pos": [ 239, 249 ] }
transrectal prostatic biopsy specimens were taken from 218 patients with prostatic symptoms-138 by the franzen aspiration technique without anaesthesia as outpatients and 80 by the silverman technique under general anaesthesia .
nichd_parent_of
{ "id": "C0002903", "name": "anaesthesia", "pos": [ 140, 151 ] }
{ "id": "C0002915", "name": "general anaesthesia", "pos": [ 207, 226 ] }
this rabies virus amplification procedure was evaluated by testing 18 lots of inactivated rabies vaccine of tissue culture origin .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 32, 41 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 46, 55 ] }
it is recommended that the amplification procedure described in this report be used in the safety testing of rabies vaccines of tissue culture origin and that it be evaluated for use in testing other rabies vaccines of low tissue content .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 41, 50 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 165, 174 ] }
emotional behavior , arousal and sleep produced by sodium and calcium ions perfused within the hypothalamus of the cat .
nichd_parent_of
{ "id": "C0004927", "name": "behavior", "pos": [ 10, 18 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 33, 38 ] }
viruses used in the system were types 1 and 2 herpes simplex virus , vaccinia virus , type 3 adenovirus , myxoma virus , pseudorabies virus , type 3 parainfluenza virus , types 1a and 13 rhinovirus , vesicular stomatitis virus , coxsackievirus b , and type 2 poliovirus .
nichd_parent_of
{ "id": "C0042776", "name": "viruses", "pos": [ 0, 7 ] }
{ "id": "C0206435", "name": "poliovirus", "pos": [ 259, 269 ] }
however , the use of sps was associated with an increased frequency of recovery of organisms judged to be contaminants , such as staphylococcus epidermidis and propionibacteria , possibly because sps enhanced the recovery of a very small inoculum of skin bacteria .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 83, 92 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 255, 263 ] }
clofibrate did not have any statistically significant effect in reducing the rate of non-fatal infarction in patients with angina or in those with myocardial infarction and pre-existing angina , though a beneficial trend was evident when both subgroups were combined ( a 44 % reduction compared with the placebo group ) .
nichd_parent_of
{ "id": "C0021308", "name": "infarction", "pos": [ 95, 105 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 147, 168 ] }
blood levels of organochlorine pesticides in argentina : occupationally and nonoccupationally exposed adults , children and newborn infants .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 111, 119 ] }
{ "id": "C0021289", "name": "newborn infants", "pos": [ 124, 139 ] }