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22 classes
Chest and waist circumferences were also significantly greater in those who developed folds or edema .
{ "id": "C0817096", "pos": [ 0, 5 ], "name": "Chest" }
{ "id": "C0013604", "pos": [ 95, 100 ], "name": "edema" }
0NA
The MR-T1 contrast enhancement measured in the tumor reported on the delivery and US-triggered release of Doxorubicin .
{ "id": "C0027651", "pos": [ 47, 52 ], "name": "tumor" }
{ "id": "C0011209", "pos": [ 69, 77 ], "name": "delivery" }
0NA
Therapy with statins plus aspirin improves long-term clinical outcome in patients after PCI .
{ "id": "C0004057", "pos": [ 26, 33 ], "name": "aspirin" }
{ "id": "C0360714", "pos": [ 13, 20 ], "name": "statins" }
0NA
Curvature variation was prescribed using the data of a human left anterior descending ( LAD ) coronary artery .
{ "id": "C0205042", "pos": [ 94, 109 ], "name": "coronary artery" }
{ "id": "C0226032", "pos": [ 88, 91 ], "name": "LAD" }
0NA
The brain benzodiazepine receptor binding of oral midazolam was significantly enhanced by pretreatment with ketoconazole , a potent inhibitor of CYP3A , whereas it was significantly reduced by treatment with dexamethasone , an inducer of this enzyme .
{ "id": "C0014442", "pos": [ 243, 249 ], "name": "enzyme" }
{ "id": "C0026056", "pos": [ 50, 59 ], "name": "midazolam" }
0NA
After 6 weeks of wrist immobilization , arthroscopy was performed due to persisting pain over the scapholunate gap , a positive Watson sign , and limited range of motion .
{ "id": "C0043262", "pos": [ 17, 22 ], "name": "wrist" }
{ "id": "C0003904", "pos": [ 40, 51 ], "name": "arthroscopy" }
0NA
Drug-induced liver injury ( DILI ) is the primary adverse event that results in withdrawal of drugs from the market and a frequent reason for the failure of drug candidates in development .
{ "id": "C0013227", "pos": [ 94, 99 ], "name": "drugs" }
{ "id": "C0860207", "pos": [ 0, 25 ], "name": "Drug-induced liver injury" }
4causative_agent_of
Common AEs reported included nasopharyngitis ( 29.5 % ) , constipation ( 19 % ) , and upper respiratory tract inflammation ( 12.4 % ) .
{ "id": "C0021368", "pos": [ 110, 122 ], "name": "inflammation" }
{ "id": "C0027441", "pos": [ 29, 44 ], "name": "nasopharyngitis" }
3associated_morphology_of
On the other hand , NaF ( 5 - 30 mM ) dose-dependently decreased the ATP content in these cells .
{ "id": "C0037508", "pos": [ 20, 23 ], "name": "NaF" }
{ "id": "C0001480", "pos": [ 69, 72 ], "name": "ATP" }
0NA
None of the patients had syphilis , atherosclerosis , abnormalities of calcium or phosphorus metabolism , lymphadenopathy , or other systemic diseases .
{ "id": "C0000768", "pos": [ 54, 67 ], "name": "abnormalities" }
{ "id": "C0039128", "pos": [ 25, 33 ], "name": "syphilis" }
0NA
That some afferent fibers from the gallbladder travel via the phrenic nerves , particularly on the right side , may be a supplementary mechanism in the generation of referred pain in gallbladder disease .
{ "id": "C0016976", "pos": [ 35, 46 ], "name": "gallbladder" }
{ "id": "C0016977", "pos": [ 183, 202 ], "name": "gallbladder disease" }
11finding_site_of
Hyperamylinemia is a condition that accompanies obesity and precedes type II diabetes , and it is characterized by above-normal blood levels of amylin , the pancreas-derived peptide .
{ "id": "C0012634", "pos": [ 21, 30 ], "name": "condition" }
{ "id": "C0011860", "pos": [ 69, 85 ], "name": "type II diabetes" }
0NA
Adequate intake of calcium and fat appears to be protective for proper bone mass accumulation factor , as well as monitoring nutritional status and serum magnesium concentration .
{ "id": "C0024467", "pos": [ 154, 163 ], "name": "magnesium" }
{ "id": "C0006675", "pos": [ 19, 26 ], "name": "calcium" }
0NA
Biodegradable scleral plugs containing pharmaceuticals have the advantage of biodegradability and the ability to fit in a relatively small diameter of 1 mm .
{ "id": "C0013227", "pos": [ 39, 54 ], "name": "pharmaceuticals" }
{ "id": "C0036572", "pos": [ 113, 116 ], "name": "fit" }
0NA
Vertebroplasty prefilling or fenestrated pedicle screw augmentation can be used to enhance pullout resistance in elderly patients .
{ "id": "C1293122", "pos": [ 55, 67 ], "name": "augmentation" }
{ "id": "C1303192", "pos": [ 0, 14 ], "name": "Vertebroplasty" }
0NA
In pure severe mitral regurgitation alone , the treatment of choice is reconstructive surgery .
{ "id": "C0524865", "pos": [ 71, 93 ], "name": "reconstructive surgery" }
{ "id": "C0026266", "pos": [ 15, 35 ], "name": "mitral regurgitation" }
0NA
In the present study , the atipamezole and/or levodopa treatments did not clearly affect on the amount of TH in the rat striata when measured by Western blot .
{ "id": "C0087111", "pos": [ 55, 65 ], "name": "treatments" }
{ "id": "C0023570", "pos": [ 46, 54 ], "name": "levodopa" }
0NA
From a health perspective , an underappreciated consequence of the normal aging process is the impacts that the gradual loss of skeletal muscle mass , termed sarcopenia , has on health beyond an effect on locomotion .
{ "id": "C0242692", "pos": [ 128, 143 ], "name": "skeletal muscle" }
{ "id": "C0872084", "pos": [ 158, 168 ], "name": "sarcopenia" }
11finding_site_of
This study describes a population of amacrine cells in the possum retina that were immunolabelled with an antibody raised against tyrosine hydroxylase ( TH ) .
{ "id": "C0035298", "pos": [ 66, 72 ], "name": "retina" }
{ "id": "C0003241", "pos": [ 106, 114 ], "name": "antibody" }
0NA
After 1 month of oral administration , there was a decrease in tumor markers .
{ "id": "C0027651", "pos": [ 63, 68 ], "name": "tumor" }
{ "id": "C0001563", "pos": [ 17, 36 ], "name": "oral administration" }
0NA
In dot-blot hybridizations the probe detected 500 pg of cloned M. teredinis rDNA .
{ "id": "C0442726", "pos": [ 37, 45 ], "name": "detected" }
{ "id": "C0182400", "pos": [ 31, 36 ], "name": "probe" }
0NA
The inhibition of heart rate was antagonized by the alpha-adrenoceptor blocking drug , phentolamine .
{ "id": "C0013227", "pos": [ 80, 84 ], "name": "drug" }
{ "id": "C0031448", "pos": [ 87, 99 ], "name": "phentolamine" }
0NA
Long-term cures in 3 patients - 6 , 8 and 13 years after resection - were achieved by cholecystectomy alone .
{ "id": "C0015252", "pos": [ 57, 66 ], "name": "resection" }
{ "id": "C0008320", "pos": [ 86, 101 ], "name": "cholecystectomy" }
0NA
To this end , we investigated the differences in sensitivity to vasoconstrictors and vasodilators between the human musculocutaneous perforator ( MCP ) artery and vein by measuring the isometric tension of arterial and venous rings suspended in organ chambers .
{ "id": "C0003842", "pos": [ 206, 214 ], "name": "arterial" }
{ "id": "C0042449", "pos": [ 163, 167 ], "name": "vein" }
0NA
A 6-year-old boy presented with hematuria in whom on x-ray and ultrasound multiple calculi were noted in the urinary bladder .
{ "id": "C0018965", "pos": [ 32, 41 ], "name": "hematuria" }
{ "id": "C0005682", "pos": [ 109, 124 ], "name": "urinary bladder" }
0NA
The changes in serum total sialic acid levels were in parallel with those of CRP in silicosis .
{ "id": "C0229671", "pos": [ 15, 20 ], "name": "serum" }
{ "id": "C0037116", "pos": [ 84, 93 ], "name": "silicosis" }
0NA
The median total number of resected metastases per operation was 9 and ranged from 0 to 65 .
{ "id": "C0015252", "pos": [ 27, 35 ], "name": "resected" }
{ "id": "C0543467", "pos": [ 51, 60 ], "name": "operation" }
0NA
The fibrosis score is therefore considered useful for estimating the severity of liver cirrhosis .
{ "id": "C0016059", "pos": [ 4, 12 ], "name": "fibrosis" }
{ "id": "C0023890", "pos": [ 81, 96 ], "name": "liver cirrhosis" }
0NA
In total , 1232 patients had 4918 pairs of successive BMD tests , with a mean 1.2   years ( ±   0.9 ) between assessments .
{ "id": "C1261322", "pos": [ 110, 121 ], "name": "assessments" }
{ "id": "C0022885", "pos": [ 58, 63 ], "name": "tests" }
17method_of
Furthermore , the location of those objects must be specified with reference to the position of the rat 's head for the rat to plan its movements .
{ "id": "C0018670", "pos": [ 107, 111 ], "name": "head" }
{ "id": "C0270724", "pos": [ 127, 131 ], "name": "plan" }
0NA
Control-regulation function of cytokine is realized at level of cell elements of brain , nerve/endocrine system .
{ "id": "C0006104", "pos": [ 81, 86 ], "name": "brain" }
{ "id": "C0079189", "pos": [ 31, 39 ], "name": "cytokine" }
0NA
For three patients with vomiting , nausea and Kernig 's and/or Brudzinski 's sign , the first diagnosis was meningitis , leading to unhelpful lumbar puncture .
{ "id": "C0025289", "pos": [ 108, 118 ], "name": "meningitis" }
{ "id": "C0037943", "pos": [ 142, 157 ], "name": "lumbar puncture" }
0NA
A minority of patients with specific abnormalities of the nose , pharynx , or jaw may require surgical management .
{ "id": "C0028429", "pos": [ 58, 62 ], "name": "nose" }
{ "id": "C0031354", "pos": [ 65, 72 ], "name": "pharynx" }
0NA
Ultrasound examination and computed tomography angiography proved an occlusion of the left subclavian artery from the origin of the vessel .
{ "id": "C0005847", "pos": [ 132, 138 ], "name": "vessel" }
{ "id": "C1536105", "pos": [ 27, 58 ], "name": "computed tomography angiography" }
9direct_procedure_site_of
In addition , the single temperature sensitive plasmid is easy to eliminate for another round of editing .
{ "id": "C0020517", "pos": [ 37, 46 ], "name": "sensitive" }
{ "id": "C0005903", "pos": [ 25, 36 ], "name": "temperature" }
0NA
In order to maximize the benefits of antiretroviral therapy , treatment programmes need to be gender sensitive to the specific needs of both women and men .
{ "id": "C0020517", "pos": [ 101, 110 ], "name": "sensitive" }
{ "id": "C0079399", "pos": [ 94, 100 ], "name": "gender" }
0NA
In the treatment group , trends were observed for reduced time to chest tube removal and earlier discharge .
{ "id": "C0015252", "pos": [ 77, 84 ], "name": "removal" }
{ "id": "C0008034", "pos": [ 66, 76 ], "name": "chest tube" }
0NA
This method is recommended for the treatment of selected fractures of the radial head followed by early mobilisation .
{ "id": "C0016658", "pos": [ 57, 66 ], "name": "fractures" }
{ "id": "C0185112", "pos": [ 104, 116 ], "name": "mobilisation" }
0NA
Non-functioning kidneys on intravenous urography ( IVU ) occurred in both malignant and infective lesions .
{ "id": "C0022646", "pos": [ 16, 23 ], "name": "kidneys" }
{ "id": "C0203108", "pos": [ 27, 48 ], "name": "intravenous urography" }
0NA
Randomized controlled trials ( RCTs ) that included adults with neurologic or musculoskeletal disease , pain as an outcome measure , and exercise in water were included .
{ "id": "C0030193", "pos": [ 104, 108 ], "name": "pain" }
{ "id": "C0043047", "pos": [ 149, 154 ], "name": "water" }
0NA
The structural abnormalities in brains of persons suffering from schizophrenia were noticed in neuropathological studies , pneumoencephalography , tomography and magnetic resonance imaging for a long time .
{ "id": "C0006104", "pos": [ 32, 38 ], "name": "brains" }
{ "id": "C0024485", "pos": [ 162, 188 ], "name": "magnetic resonance imaging" }
0NA
The ultrasound of the thyroid showed a normoechogenic pattern .
{ "id": "C0040132", "pos": [ 22, 29 ], "name": "thyroid" }
{ "id": "C0041618", "pos": [ 4, 14 ], "name": "ultrasound" }
0NA
From this , it was concluded that test Group II was more efficient in root debridement than test Group 1 , so scaling and root planing done with magnification loupes will cause less damage to the tooth surface .
{ "id": "C0010957", "pos": [ 182, 188 ], "name": "damage" }
{ "id": "C0447301", "pos": [ 196, 209 ], "name": "tooth surface" }
0NA
We report on the correlations between whole brain rCBF and the positive and negative symptoms of schizophrenia in two cohorts of patients who were scanned while free of antipsychotic medication .
{ "id": "C0006104", "pos": [ 44, 49 ], "name": "brain" }
{ "id": "C0036341", "pos": [ 97, 110 ], "name": "schizophrenia" }
0NA
Patients were randomized to receive either intravenous amisulpride ( 5   mg ) or matching placebo at induction of general anesthesia , in addition to one standard , nondopaminergic antiemetic , most commonly ondansetron or dexamethasone .
{ "id": "C0011777", "pos": [ 223, 236 ], "name": "dexamethasone" }
{ "id": "C0061851", "pos": [ 208, 219 ], "name": "ondansetron" }
0NA
In healthy humans , TNF-alpha infusion induces skeletal muscle insulin resistance .
{ "id": "C0242692", "pos": [ 47, 62 ], "name": "skeletal muscle" }
{ "id": "C0574032", "pos": [ 30, 38 ], "name": "infusion" }
0NA
PGE2 stimulated glycoprotein and protein synthesis ( EC50 7 and 30 nmol/L , respectively ) and release ( EC50 50 and 140 nmol/L , respectively ) in a concentration-dependent manner , whereas carbenoxolone , CCK-OP and U46619 failed to enhance the incorporation of the tracers .
{ "id": "C0006979", "pos": [ 191, 204 ], "name": "carbenoxolone" }
{ "id": "C0012472", "pos": [ 0, 4 ], "name": "PGE2" }
0NA
CCK-8 assay and flow cytometry were used to determine proliferation , cell cycle distribution and apoptosis of cardiomyocytes in each group after transfection .
{ "id": "C0334094", "pos": [ 54, 67 ], "name": "proliferation" }
{ "id": "C0037167", "pos": [ 0, 5 ], "name": "CCK-8" }
0NA
Discriminant analysis eliminated the overlap in free radical marker and selenium concentrations between control sera on the one hand and baseline or post-placebo samples from the patients on the other : antioxidant treatment normalized the relationship between these biochemical parameters .
{ "id": "C0229671", "pos": [ 112, 116 ], "name": "sera" }
{ "id": "C0185027", "pos": [ 37, 44 ], "name": "overlap" }
0NA
The diagnosis was confirmed at bronchoscopy and was successfully treated by thoracotomy and primary closure of a 3-cm rent in the membranous portion of the trachea .
{ "id": "C0040578", "pos": [ 156, 163 ], "name": "trachea" }
{ "id": "C0039991", "pos": [ 76, 87 ], "name": "thoracotomy" }
0NA
Histological grading is mandatory in the management of carcinoma of the penis .
{ "id": "C0030851", "pos": [ 72, 77 ], "name": "penis" }
{ "id": "C0007097", "pos": [ 55, 64 ], "name": "carcinoma" }
0NA
The progression of renal failure has been suggested to be altered by dietary manipulation of protein based on the presumption that the progressive nature of CRF may be caused by the vicious cycle driven by some toxic metabolite uncleared by failing kidney .
{ "id": "C0022646", "pos": [ 249, 255 ], "name": "kidney" }
{ "id": "C0035078", "pos": [ 19, 32 ], "name": "renal failure" }
11finding_site_of
Screening of new drugs using animal models and specifically molecular imaging before human studies is an approach used extensively by the pharmaceutical industry .
{ "id": "C0013227", "pos": [ 17, 22 ], "name": "drugs" }
{ "id": "C0199230", "pos": [ 0, 9 ], "name": "Screening" }
0NA
These toxins also caused cessation of the spontaneous beating and degeneration of cultured foetal mouse heart cells .
{ "id": "C0011164", "pos": [ 66, 78 ], "name": "degeneration" }
{ "id": "C0040549", "pos": [ 6, 12 ], "name": "toxins" }
0NA
Addition of placentrex leads to marked improvement in dyspareunia , less fornix tenderness and better uterine mobility suggesting better effect on adnexal tissues and parametrium .
{ "id": "C0227822", "pos": [ 167, 178 ], "name": "parametrium" }
{ "id": "C0040300", "pos": [ 155, 162 ], "name": "tissues" }
0NA
There was one postoperative haemarthrosis and one failed fixation , which needed surgical revision .
{ "id": "C0185023", "pos": [ 57, 65 ], "name": "fixation" }
{ "id": "C0018924", "pos": [ 28, 41 ], "name": "haemarthrosis" }
0NA
While spatial asynergy at end-systole has been well characterized in patients with coronary artery disease , assessment of regional asynchrony has been hampered by technical constraints .
{ "id": "C0031809", "pos": [ 109, 119 ], "name": "assessment" }
{ "id": "C0010054", "pos": [ 83, 106 ], "name": "coronary artery disease" }
0NA
We present our results of preemptive treatment with pegylated interferon and ribavirin after liver transplantation for hepatitis C cirrhosis .
{ "id": "C0023911", "pos": [ 93, 114 ], "name": "liver transplantation" }
{ "id": "C0035525", "pos": [ 77, 86 ], "name": "ribavirin" }
0NA
The increasing implantation rates of total hip and knee prostheses have been accompanied by a corresponding rise in periprosthetic fractures ( PPF ) , most often affecting the femur .
{ "id": "C0015811", "pos": [ 176, 181 ], "name": "femur" }
{ "id": "C0021107", "pos": [ 15, 27 ], "name": "implantation" }
0NA
We analyzed the simultaneous subdural and scalp interictal EEG recordings of 14 patients with refractory frontal lobe epilepsy ( FLE ) associated with focal cortical dysplasia .
{ "id": "C0036270", "pos": [ 42, 47 ], "name": "scalp" }
{ "id": "C0038541", "pos": [ 29, 37 ], "name": "subdural" }
0NA
However , the presence of hydronephrosis does not define obstruction and displays unique behavior in the newborn .
{ "id": "C0028778", "pos": [ 57, 68 ], "name": "obstruction" }
{ "id": "C0020295", "pos": [ 26, 40 ], "name": "hydronephrosis" }
3associated_morphology_of
During the period January 1983 to December 1993 malformations of the urinary tract were suspected in 166 cases prenatally and confirmed after birth .
{ "id": "C0000768", "pos": [ 48, 61 ], "name": "malformations" }
{ "id": "C0005615", "pos": [ 142, 147 ], "name": "birth" }
0NA
Blood flow restricted ( BFR ) training , the brief and partial restriction of venous outflow of an extremity during low load resistance exercises , is a safe and effective method of improving strength in healthy , active individuals .
{ "id": "C0015385", "pos": [ 99, 108 ], "name": "extremity" }
{ "id": "C0232338", "pos": [ 0, 10 ], "name": "Blood flow" }
0NA
The procedure is not time consuming , and staples are not required .
{ "id": "C0524724", "pos": [ 42, 49 ], "name": "staples" }
{ "id": "C0184661", "pos": [ 4, 13 ], "name": "procedure" }
0NA
Thirty-one percent of the children injured in playground accidents sustained fractures of the extremities or concussion of the brain .
{ "id": "C0006104", "pos": [ 127, 132 ], "name": "brain" }
{ "id": "C0006107", "pos": [ 109, 119 ], "name": "concussion" }
11finding_site_of
The putative gut microbial function may also contribute to the assembly and secretion of very-low-density lipoproteins from the liver to the plasma .
{ "id": "C0023884", "pos": [ 128, 133 ], "name": "liver" }
{ "id": "C0032105", "pos": [ 141, 147 ], "name": "plasma" }
0NA
According to different gene families the MHC is subdivided into a class I , class II and class III region and many of its gene products are associated with the immune system and the susceptibility to various diseases .
{ "id": "C0020962", "pos": [ 160, 173 ], "name": "immune system" }
{ "id": "C0012634", "pos": [ 208, 216 ], "name": "diseases" }
0NA
Radiation also has proven effective in the management of other tumor-related symptoms , including bleeding , neurologic compromise , dysphagia , and airway obstruction .
{ "id": "C0019080", "pos": [ 98, 106 ], "name": "bleeding" }
{ "id": "C0001883", "pos": [ 149, 167 ], "name": "airway obstruction" }
0NA
Surgical treatment consisted in a right hemicolectomy .
{ "id": "C0192861", "pos": [ 34, 53 ], "name": "right hemicolectomy" }
{ "id": "C0543467", "pos": [ 0, 18 ], "name": "Surgical treatment" }
0NA
In explanted liver , the mean diameter of the radiofrequency-induced lesion was 5.3 + /- 0.7 cm for the cooled-tip needle and 3.7 + /- 0.4 cm for the expandable needle ( p = 0.042 ) , which correspond to approximate volumes of 65.35 + /- 26.22 cm(3 ) and 26.67 + /- 9.59 cm(3 ) , respectively ( p < 0.002 ) .
{ "id": "C0221198", "pos": [ 69, 75 ], "name": "lesion" }
{ "id": "C0023884", "pos": [ 13, 18 ], "name": "liver" }
0NA
The 24 tumors analyzed had similar growth kinetics , with an average doubling time of approximately 16.4 d. Levels of the p53 codon 270 mutation were quantified in the 24 mouse skin tumors using allele-specific competitive blocker-polymerase chain reaction ( ACB-PCR ) .
{ "id": "C0027651", "pos": [ 7, 13 ], "name": "tumors" }
{ "id": "C0037286", "pos": [ 177, 188 ], "name": "skin tumors" }
3associated_morphology_of
Extending the duration of infusion increases the total cumulative dose of carboplatin and etoposide that can be administered without increasing adverse effects .
{ "id": "C0015133", "pos": [ 90, 99 ], "name": "etoposide" }
{ "id": "C0574032", "pos": [ 26, 34 ], "name": "infusion" }
0NA
Paragangliomas are rare tumors arising from extraadrenal chromaffin cells .
{ "id": "C0027651", "pos": [ 24, 30 ], "name": "tumors" }
{ "id": "C0030421", "pos": [ 0, 14 ], "name": "Paragangliomas" }
3associated_morphology_of
We investigated the causes of this persisting low percentage of MOD by studying the reasons for kidney donation only .
{ "id": "C0011860", "pos": [ 64, 67 ], "name": "MOD" }
{ "id": "C0411257", "pos": [ 96, 111 ], "name": "kidney donation" }
0NA
The development of technologically advanced , expensive techniques has progressively reduced the value of chest X-ray in clinical practice for the assessment of left ventricular ( LV ) dilatation and dysfunction .
{ "id": "C0031809", "pos": [ 147, 157 ], "name": "assessment" }
{ "id": "C0039985", "pos": [ 106, 117 ], "name": "chest X-ray" }
0NA
The environmental risk factors of AD/DAT include brain injury , viral infections , neutroxic chemicals , various immunological and hormonal disorders .
{ "id": "C0220806", "pos": [ 93, 102 ], "name": "chemicals" }
{ "id": "C0042769", "pos": [ 64, 80 ], "name": "viral infections" }
0NA
The high incidence of tendon injuries is frequently associated with sports practice , aging , tendinopathies , hypertension , diabetes mellitus , and the use of corticosteroids .
{ "id": "C0011849", "pos": [ 126, 143 ], "name": "diabetes mellitus" }
{ "id": "C0020538", "pos": [ 111, 123 ], "name": "hypertension" }
0NA
The liver cirrhosis indices HA and PC-III in patients with the asthenia of liver and kidney yin syndrome were significantly different to those of the internal accumulation of damp-heat syndrome ( P < 0.05 ) .
{ "id": "C0023884", "pos": [ 75, 80 ], "name": "liver" }
{ "id": "C0023890", "pos": [ 4, 19 ], "name": "liver cirrhosis" }
11finding_site_of
A descending thoracic aorta that traverses the midline is an uncommon cause of airway compression affecting the distal trachea and proximal main bronchi .
{ "id": "C1522460", "pos": [ 2, 27 ], "name": "descending thoracic aorta" }
{ "id": "C0006255", "pos": [ 145, 152 ], "name": "bronchi" }
0NA
Because numerous important discoveries in the PAH pathogenesis have been recently made , our improved understanding of additional pathways in this condition will presumably lead to the development of novel and more powerful therapeutic strategies in the near future .
{ "id": "C0012634", "pos": [ 147, 156 ], "name": "condition" }
{ "id": "C0475806", "pos": [ 254, 258 ], "name": "near" }
0NA
RCC is highly resistant to chemotherapy .
{ "id": "C0007134", "pos": [ 0, 3 ], "name": "RCC" }
{ "id": "C0013216", "pos": [ 27, 39 ], "name": "chemotherapy" }
0NA
However , increased bacterial resistance to antimicrobial agents has made it difficult for dermatologists to prescribe appropriate medication .
{ "id": "C0013227", "pos": [ 131, 141 ], "name": "medication" }
{ "id": "C1136254", "pos": [ 44, 64 ], "name": "antimicrobial agents" }
0NA
Seven crystal structures of alanyl aminopeptidase from Neisseria meningitides ( the etiological agent of meningitis , NmAPN ) complexed with organophosphorus compounds were resolved to determine the optimal inhibitor-enzyme interactions .
{ "id": "C0054943", "pos": [ 28, 49 ], "name": "alanyl aminopeptidase" }
{ "id": "C0025289", "pos": [ 105, 115 ], "name": "meningitis" }
0NA
In 12 patient who were asymptomatic EUS was positive in 12 , digital rectal examination in 5 , computer tomography in 9 , colonoscopy in 8 , and the CEA was increased in 4 .
{ "id": "C1446409", "pos": [ 44, 52 ], "name": "positive" }
{ "id": "C0376443", "pos": [ 36, 39 ], "name": "EUS" }
0NA
Hypoplasia of the fetal lung is found in association with long-standing oligohydramnios .
{ "id": "C0024109", "pos": [ 24, 28 ], "name": "lung" }
{ "id": "C0079924", "pos": [ 72, 87 ], "name": "oligohydramnios" }
0NA
One of the most studied organs for the effects of CAPE is the kidney , particularly in the capacity of this ester to decrease the nephrotoxicity induced by several drugs and the oxidative injury after ischemia/reperfusion ( I/R ) .
{ "id": "C0022646", "pos": [ 62, 68 ], "name": "kidney" }
{ "id": "C0595916", "pos": [ 130, 144 ], "name": "nephrotoxicity" }
11finding_site_of
Laparoscopic repair of inguinal hernia is traditionally performed under general anesthesia mainly because of the adverse effects that carbon dioxide pneumoperitoneum has on awake patients .
{ "id": "C0234422", "pos": [ 173, 178 ], "name": "awake" }
{ "id": "C0032320", "pos": [ 149, 165 ], "name": "pneumoperitoneum" }
0NA
Moreover , a desensitization or mutation of these receptors may also occur in tumors .
{ "id": "C0027651", "pos": [ 78, 84 ], "name": "tumors" }
{ "id": "C0178702", "pos": [ 13, 28 ], "name": "desensitization" }
0NA
Biopsies were also ( - ) for gastric carcinoma , lymphoma and plasmacytoma .
{ "id": "C0005558", "pos": [ 0, 8 ], "name": "Biopsies" }
{ "id": "C0699791", "pos": [ 29, 46 ], "name": "gastric carcinoma" }
0NA
Paced atria , in which spontaneous rate changes were absent , revealed a sharper tension optimum at an unaltered temperature .
{ "id": "C0233494", "pos": [ 81, 88 ], "name": "tension" }
{ "id": "C0005903", "pos": [ 113, 124 ], "name": "temperature" }
0NA
Portal cavernoma cholangiopathy ( formerly portal biliopathy ) is a type of biliary injury that occurs in association with a portal vein thrombus or cavernoma .
{ "id": "C0087086", "pos": [ 137, 145 ], "name": "thrombus" }
{ "id": "C0018920", "pos": [ 149, 158 ], "name": "cavernoma" }
0NA
It is frequently followed by a post-withdrawal period of several weeks duration with crying , excitability , sleep irregularities and feeding difficulties .
{ "id": "C1299586", "pos": [ 142, 154 ], "name": "difficulties" }
{ "id": "C0025344", "pos": [ 47, 53 ], "name": "period" }
0NA
During maintenance a dilatation of the intercellular spaces developed in both secretory coil and collecting duct .
{ "id": "C0002940", "pos": [ 21, 31 ], "name": "dilatation" }
{ "id": "C0222607", "pos": [ 97, 112 ], "name": "collecting duct" }
0NA
All numbers and statistical data on oesophagus late effects should be regarded with caution due to recent changes in the therapeutic attitudes ( more and more combined chemotherapy-radiotherapy ) and some progress in given cancer locations .
{ "id": "C0014876", "pos": [ 36, 46 ], "name": "oesophagus" }
{ "id": "C0006826", "pos": [ 223, 229 ], "name": "cancer" }
0NA
In an on-treatment analysis , first-line therapy with any of the PIs significantly reduced HIV-1 concentrations and increased CD4 T-cell counts and percentages from baseline throughout the 288-week study ( P < or= 0.05 ) for ritonavir and nelfinavir and throughout 84 weeks of use for lopinavir/ritonavir , which was introduced into treatment more recently .
{ "id": "C0292818", "pos": [ 225, 234 ], "name": "ritonavir" }
{ "id": "C0939237", "pos": [ 285, 304 ], "name": "lopinavir/ritonavir" }
1active_ingredient_of
Overall , our findings expand and quantify earlier impressions that , compared to UVB , UVA has a relatively greater histologic effect on the dermis than on the epidermis , depletes epidermal Langerhans cells , and recruits neutrophils into irradiated human skin .
{ "id": "C0014520", "pos": [ 161, 170 ], "name": "epidermis" }
{ "id": "C0011646", "pos": [ 142, 148 ], "name": "dermis" }
0NA
We report a retrospective analysis of 25 knees treated with the same technique from 1983 to 2004 : reconstruction with a single transplant taken from the extensor system .
{ "id": "C0022742", "pos": [ 41, 46 ], "name": "knees" }
{ "id": "C0040732", "pos": [ 128, 138 ], "name": "transplant" }
0NA
The regenerative endodontic procedure allowed the continued development of roots in teeth with necrotic pulps .
{ "id": "C0040426", "pos": [ 84, 89 ], "name": "teeth" }
{ "id": "C0700632", "pos": [ 17, 37 ], "name": "endodontic procedure" }
19procedure_site_of
The effect of ultrasound on the pseudo-solubility of nitrogen in water and on gas-liquid mass transfer kinetics has been investigated in an autoclave reactor equipped with a gas induced impeller .
{ "id": "C0041618", "pos": [ 14, 24 ], "name": "ultrasound" }
{ "id": "C0028158", "pos": [ 53, 61 ], "name": "nitrogen" }
0NA
Mice lacking the IL1R1 exhibited adrenal hypertrophy , thymic involution , and elevated serum corticosterone levels in response to the stressor but did not show splenic accumulation of CD11b(+ ) cells and failed to develop GC resistance .
{ "id": "C0229671", "pos": [ 88, 93 ], "name": "serum" }
{ "id": "C0037993", "pos": [ 161, 168 ], "name": "splenic" }
0NA