instruction stringlengths 223 1.46k | input stringlengths 68 1.85k | response stringlengths 3 12 |
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<Instruct>: Given the context 'Captopril had little or no demonstrable effects on serum electrolyte concentrations, excretion of urine, sodium and potassium, endogenous creatinine clearance, body weight, and food and water consumption.', select the correct biomedical concept for each mention using the provided options.... | <Mentions>: [captopril; sodium; potassium; creatinine]
<Options>: A: potassium phosphate
B: preparation k
C: salt, creatinine sulfate (aka creatinine)
D: sodium, dietary
E: captopril disulfide
F: epoxycreatine
G: pentopril (aka cgs 13945)
H: potassium
I: sodium chloride
J: level, sodium ion (aka sodium)
K: creolin
L: a... | [M; J; H; C] |
<Instruct>: Given the context 'Captopril had little or no demonstrable effects on serum electrolyte concentrations, excretion of urine, sodium and potassium, endogenous creatinine clearance, body weight, and food and water consumption.', select the correct biomedical concept for each mention using the provided options.... | <Mentions>: [captopril; sodium; potassium; creatinine]
<Options>: A: sodium nitrate
B: captopril disulfide
C: captan
D: glutamate, sodium (aka sodium glutamate)
E: sodium nitrite
F: citrinacetal
G: potassium
H: carnitine
I: potassium fluoride
J: (s)-1-(3-mercapto-2-methyl-1-oxopropyl)-l-proline (aka captopril)
K: potas... | [J; T; G; Q] |
<Instruct>: Given the context 'However, ketone bodies were consistently present in urine and several lethalities occurred during multiple dosing of captopril in SHR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separa... | <Mentions>: [ketone; captopril]
<Options>: A: ketone bodies
B: s-benzoyl captopril
C: butanones
D: captopril, hydrochlorothiazide drug combination
E: ketones
F: acetone, acetonyl (aka 2,5-hexanedione)
G: captagon (aka fenethylline)
H: cyclohexanone
I: (s)-1-(3-mercapto-2-methyl-1-oxopropyl)-l-proline (aka captopril)
J:... | [E; I] |
<Instruct>: Given the context 'However, ketone bodies were consistently present in urine and several lethalities occurred during multiple dosing of captopril in SHR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separa... | <Mentions>: [ketone; captopril]
<Options>: A: (s)-1-(3-mercapto-2-methyl-1-oxopropyl)-l-proline (aka captopril)
B: captan
C: methyl ethyl ketone (aka methylethyl ketone)
D: captagon (aka fenethylline)
E: tiopronin
F: diethyl ketone
G: ketone bodies
H: ketones
I: captisol (aka sbe4-beta-cyclodextrin)
J: monoterpene keto... | [H; A] |
<Instruct>: Given the context 'However, ketone bodies were consistently present in urine and several lethalities occurred during multiple dosing of captopril in SHR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separa... | <Mentions>: [ketone; captopril]
<Options>: A: methyl ethyl ketone (aka methylethyl ketone)
B: monoterpene ketones (aka monoterpene aldehydes and ketones)
C: captisol (aka sbe4-beta-cyclodextrin)
D: tiopronin
E: captagon (aka fenethylline)
F: diethyl ketone
G: (s)-1-(3-mercapto-2-methyl-1-oxopropyl)-l-proline (aka capto... | [J; G] |
<Instruct>: Given the context 'Epileptogenic properties of enflurane and their clinical interpretation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [enflurane]
<Options>: A: eefe ether (aka 2-(2-ethoxyethoxy)ethyl furfuryl ether)
B: 2,2,2-trifluoroethyl ethyl ether
C: difluoroethyne
D: ethrane (aka enflurane)
E: norflurane
F: None of the above. | [D] |
<Instruct>: Given the context 'Three cases of EEG changes induced by single exposure to enflurane anesthesia are reported.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [enflurane]
<Options>: A: isoflurane
B: ethane
C: ether, diethyl (aka ether)
D: ethrane (aka enflurane)
E: difluoroethyne
F: None of the above. | [D] |
<Instruct>: Given the context 'In one patient, enflurane administered during a donor nephrectomy resulted in unexpected partial motor seizures.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [enflurane]
<Options>: A: enflurane
B: eefe ether (aka 2-(2-ethoxyethoxy)ethyl furfuryl ether)
C: 2,2,2-trifluoroethyl ethyl ether
D: sevoflurane
E: ethane
F: None of the above. | [A] |
<Instruct>: Given the context 'Epileptic foci delineated and activated by enflurane were surgically ablated and the patients are now seizure-free.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [enflurane]
<Options>: A: ethrane (aka enflurane)
B: fluenethyl
C: sevoflurane
D: pentafluoroethane
E: 2,2,2-trifluoroethyl ethyl ether
F: None of the above. | [A] |
<Instruct>: Given the context 'Previous exposures to enflurane have to be disclosed to avoid mistakes in clinical interpretation of the EEG.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [enflurane]
<Options>: A: diethyl ether (aka ether)
B: ethylene tetrafluoroethylene (aka poly(ethylene-tetrafluoroethylene))
C: ethrane (aka enflurane)
D: desflurane
E: difluoroethyne
F: None of the above. | [C] |
<Instruct>: Given the context 'On the other hand, enflurane may prove to be a safe fast acting activator of epileptic foci during corticography or depth electrode intraoperative recordings.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one ... | <Mentions>: [enflurane]
<Options>: A: ethrane (aka enflurane)
B: ethoform (aka benzocaine)
C: 2,2,2-trifluoroethyl ethyl ether
D: sevoflurane
E: diethylene ether (aka 1,4-dioxane)
F: None of the above. | [A] |
<Instruct>: Given the context 'Reversible cerebral lesions associated with tiazofurin usage: MR demonstration.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [tiazofurin]
<Options>: A: thiophenfurin
B: tiazole (aka tiazofurin)
C: furazosin (aka prazosin)
D: 1-(2,3,4,5-tetrahydro-5-oxo-2-furyl)-2-n-(p-toluenesulfonyl)-1,2,3,4-tetrahydroisoquinoline
E: tetrahydrokalafungin
F: None of the above. | [B] |
<Instruct>: Given the context 'Tiazofurin is an experimental chemotherapeutic agent currently undergoing clinical evaluation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [tiazofurin]
<Options>: A: thiophenfurin
B: tetrahydrokalafungin
C: 2-(trifluoromethyl)-2-oxazoline
D: tiazole (aka tiazofurin)
E: tiazofurin monophosphate
F: None of the above. | [D] |
<Instruct>: Given the context 'Antagonism of diazepam-induced sedative effects by Ro15-1788 in patients after surgery under lumbar epidural block.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [diazepam; ro15-1788]
<Options>: A: ro 15 1788 (aka flumazenil)
B: ro11-3128 (aka meclonazepam)
C: n-desmethylquazepam
D: chlordemethyldiazepam (aka chlordesmethyldiazepam)
E: ro 14-0518
F: ro-14-9578 (aka ro 14-9578)
G: clotiazepam
H: desmethyldiazepam (aka nordazepam)
I: ro 17-2218, monohydrochloride (aka... | [J; A] |
<Instruct>: Given the context 'Antagonism of diazepam-induced sedative effects by Ro15-1788 in patients after surgery under lumbar epidural block.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [diazepam; ro15-1788]
<Options>: A: diazepam
B: ro 17-2218, monohydrochloride (aka ro 17-2218)
C: ro-14-9578 (aka ro 14-9578)
D: ro11-3128 (aka meclonazepam)
E: chlordemethyldiazepam (aka chlordesmethyldiazepam)
F: desmethyldiazepam (aka nordazepam)
G: clotiazepam
H: ro 14-0518
I: n-desmethylquazepam
J: Non... | [A; J] |
<Instruct>: Given the context 'Antagonism of diazepam-induced sedative effects by Ro15-1788 in patients after surgery under lumbar epidural block.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [diazepam; ro15-1788]
<Options>: A: benzodiazepine (aka benzodiazepines)
B: ro 15 1788 (aka flumazenil)
C: 1,4-benzodiazepine (aka bz-423)
D: desmethylmedazepam
E: diazepam
F: ro-31-1118 (aka flusoxolol)
G: ro11-3128 (aka meclonazepam)
H: ro 13-3978
I: ro 17-2218, monohydrochloride (aka ro 17-2218)
J: dilaz... | [E; B] |
<Instruct>: Given the context 'The aim of this study was to assess the efficacy of Ro15-1788 and a placebo in reversing diazepam-induced effects after surgery under epidural block, and to evaluate the local tolerance and general safety of Ro15-1788.', select the correct biomedical concept for each mention using the pro... | <Mentions>: [ro15-1788; diazepam]
<Options>: A: d-n-benzodiazepine-dione (aka 7,8-dichloro-6-nitro-1h-1,5-benzodiazepine-2,4-(3h,5h)-dione)
B: ro15-5458 (aka ro 15-5458)
C: ro 15-9268
D: ro113-2908
E: desmethylmedazepam
F: ro11-3128 (aka meclonazepam)
G: diazepam
H: ro 15 1788 (aka flumazenil)
I: diethylzinc
J: 1,4-ben... | [H; G] |
<Instruct>: Given the context 'The aim of this study was to assess the efficacy of Ro15-1788 and a placebo in reversing diazepam-induced effects after surgery under epidural block, and to evaluate the local tolerance and general safety of Ro15-1788.', select the correct biomedical concept for each mention using the pro... | <Mentions>: [ro15-1788; diazepam]
<Options>: A: ro15-5458 (aka ro 15-5458)
B: benzodiazepinones
C: chlordemethyldiazepam (aka chlordesmethyldiazepam)
D: ro 31-1118 (aka flusoxolol)
E: binding inhibitor, diazepam (aka diazepam binding inhibitor)
F: ro 10-3108 (aka epofenonane)
G: ro 13-3978
H: diazepam
I: d-n-benzodiaze... | [J; H] |
<Instruct>: Given the context 'Fifty-seven patients were sedated with diazepam for surgery under epidural anaesthesia.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [diazepam]
<Options>: A: 1h-1,4-benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl- (aka medazepam)
B: chlordemethyldiazepam (aka chlordesmethyldiazepam)
C: d-n-benzodiazepine-dione (aka 7,8-dichloro-6-nitro-1h-1,5-benzodiazepine-2,4-(3h,5h)-dione)
D: demethyldiazepam (aka nordazepam)
E: diazepam
F: Non... | [E] |
<Instruct>: Given the context 'Antagonism of diazepam-induced effects by Ro15-1788 was investigated postoperatively in a double-blind placebo-controlled trial.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by... | <Mentions>: [diazepam; ro15-1788]
<Options>: A: ro 151788 (aka flumazenil)
B: ro113-2908
C: binding inhibitor, diazepam (aka diazepam binding inhibitor)
D: ro 11-1781 (aka tiapamil hydrochloride)
E: d-n-benzodiazepine-dione (aka 7,8-dichloro-6-nitro-1h-1,5-benzodiazepine-2,4-(3h,5h)-dione)
F: ro 15-0778 (aka temarotene... | [G; A] |
<Instruct>: Given the context 'Antagonism of diazepam-induced effects by Ro15-1788 was investigated postoperatively in a double-blind placebo-controlled trial.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by... | <Mentions>: [diazepam; ro15-1788]
<Options>: A: diazepam
B: desmethyldiazepam (aka nordazepam)
C: n-desmethylquazepam
D: 1h-1,4-benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl- (aka medazepam)
E: ro113-2908
F: ro 15-0778 (aka temarotene)
G: diethylzinc
H: ro 13-3978
I: ro 15 1788 (aka flumazenil)
J: ro11-3128 (a... | [A; I] |
<Instruct>: Given the context 'The Ro15-1788 group showed a significant improvement in the performance test up to 120 min after administration of the drug.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by sem... | <Mentions>: [ro15-1788]
<Options>: A: ro 15-1788 (aka flumazenil)
B: ro 31-1118 (aka flusoxolol)
C: ro11-3128 (aka meclonazepam)
D: ro 14-0518
E: ro 15-0778 (aka temarotene)
F: None of the above. | [A] |
<Instruct>: Given the context 'Enhanced stimulus-induced neurotransmitter overflow in epinephrine-induced hypertensive rats is not mediated by prejunctional beta-adrenoceptor activation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for... | <Mentions>: [epinephrine]
<Options>: A: ethylnorepinephrine
B: adrenaline (aka epinephrine)
C: epinemin
D: norepinephrine
E: adrenergic (aka adrenergic agents)
F: None of the above. | [B] |
<Instruct>: Given the context 'The present study examines the effect of 6-day epinephrine treatment (100 micrograms/kg per h, s.c.)', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [epinephrine]
<Options>: A: adrenalone
B: adrenaline (aka epinephrine)
C: epinemin
D: epinephrine, racemic mixture (aka racepinephrine)
E: alpha-methylepinephrine
F: None of the above. | [B] |
<Instruct>: Given the context 'on stimulus-induced (1 Hz) endogenous neurotransmitter overflow from the isolated perfused kidney of vehicle- and epinephrine-treated rats.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, s... | <Mentions>: [epinephrine]
<Options>: A: epinephrine
B: adrenalone
C: deoxyepinephrine
D: alpha-methylepinephrine, erythro-(-)-isomer (aka alpha-methylepinephrine)
E: ethylphenylephrine (aka etilefrine)
F: None of the above. | [A] |
<Instruct>: Given the context 'Renal catecholamine stores and stimulus-induced overflow in the vehicle-treated group consisted of norepinephrine only.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolo... | <Mentions>: [catecholamine; norepinephrine]
<Options>: A: catecholine (aka n,n-dimethylepinephrine)
B: norepinephrine, (+)-isomer (aka norepinephrine)
C: catecholamine (aka catecholamines)
D: levorine (aka candicidin)
E: norphenylephrine (aka norfenefrine)
F: catecholamphetamine (aka alpha-methyldopamine)
G: sympathomi... | [C; B] |
<Instruct>: Given the context 'Renal catecholamine stores and stimulus-induced overflow in the vehicle-treated group consisted of norepinephrine only.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolo... | <Mentions>: [catecholamine; norepinephrine]
<Options>: A: ethylnorepinephrine
B: sympathomimetics
C: norepinephrine
D: catecholamphetamine (aka alpha-methyldopamine)
E: norphenylephrine (aka norfenefrine)
F: norepinephrine, (+)-isomer (aka norepinephrine)
G: catecholine (aka n,n-dimethylepinephrine)
H: norephrine (aka ... | [J; F] |
<Instruct>: Given the context 'However, epinephrine treatment resulted in the incorporation of epinephrine into renal catecholamine stores such that approximately 40% of the catecholamine present was epinephrine while the norepinephrine content was reduced by a similar degree.', select the correct biomedical concept fo... | <Mentions>: [epinephrine; catecholamine]
<Options>: A: catecholamine (aka catecholamines)
B: catecholine (aka n,n-dimethylepinephrine)
C: epinephrine
D: adrenalone
E: sympathin (aka catecholamines)
F: catecholamphetamine (aka alpha-methyldopamine)
G: metanephrine
H: adrenergic (aka adrenergic agents)
I: norepinephrine
... | [C; A] |
<Instruct>: Given the context 'However, epinephrine treatment resulted in the incorporation of epinephrine into renal catecholamine stores such that approximately 40% of the catecholamine present was epinephrine while the norepinephrine content was reduced by a similar degree.', select the correct biomedical concept fo... | <Mentions>: [epinephrine; catecholamine]
<Options>: A: adrenalone
B: catecholamines
C: catecholine (aka n,n-dimethylepinephrine)
D: alpha-methylepinephrine, erythro-(-)-isomer (aka alpha-methylepinephrine)
E: epinephrine
F: norepinephrine
G: catecholamphetamine (aka alpha-methyldopamine)
H: epinephrine, racemic mixture... | [E; B] |
<Instruct>: Given the context 'However, epinephrine treatment resulted in the incorporation of epinephrine into renal catecholamine stores such that approximately 40% of the catecholamine present was epinephrine while the norepinephrine content was reduced by a similar degree.', select the correct biomedical concept fo... | <Mentions>: [epinephrine; norepinephrine]
<Options>: A: catecholamine (aka catecholamines)
B: norphenylephrine (aka norfenefrine)
C: ethylphenylephrine (aka etilefrine)
D: catecholamines
E: levorine (aka candicidin)
F: metanephrine
G: levonor (aka norepinephrine)
H: epinephrine
I: norephrine (aka nordefrin)
J: None of ... | [H; G] |
<Instruct>: Given the context 'However, epinephrine treatment resulted in the incorporation of epinephrine into renal catecholamine stores such that approximately 40% of the catecholamine present was epinephrine while the norepinephrine content was reduced by a similar degree.', select the correct biomedical concept fo... | <Mentions>: [epinephrine; norepinephrine]
<Options>: A: norepinephrine
B: norepinephrine glucuronide
C: epinephrine
D: norepinephrine, (+,-)-isomer (aka norepinephrine)
E: epinemin
F: norsynephrine (aka octopamine)
G: norphenylephrine (aka norfenefrine)
H: ethylnorepinephrine
I: adrenergic (aka adrenergic agents)
J: No... | [C; D] |
<Instruct>: Given the context 'Total tissue catecholamine content of the kidney on a molar basis was unchanged.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [catecholamine]
<Options>: A: catecholine (aka n,n-dimethylepinephrine)
B: catecholamphetamine (aka alpha-methyldopamine)
C: norepinephrine
D: adrenergic (aka adrenergic agents)
E: catecholamines
F: None of the above. | [E] |
<Instruct>: Given the context 'Stimulus-induced fractional overflow of neurotransmitter from the epinephrine-treated kidneys was approximately twice normal and consisted of both norepinephrine and epinephrine in proportions similar to those found in the kidney.', select the correct biomedical concept for each mention u... | <Mentions>: [epinephrine; norepinephrine]
<Options>: A: norphenylephrine (aka norfenefrine)
B: metanephrine
C: noradrenalone
D: adrenalone
E: adrenaline (aka epinephrine)
F: norsynephrine (aka octopamine)
G: norepinephrine, (+)-isomer (aka norepinephrine)
H: norepinephrine glucuronide
I: ethylnorepinephrine
J: None of ... | [E; G] |
<Instruct>: Given the context 'Stimulus-induced fractional overflow of neurotransmitter from the epinephrine-treated kidneys was approximately twice normal and consisted of both norepinephrine and epinephrine in proportions similar to those found in the kidney.', select the correct biomedical concept for each mention u... | <Mentions>: [epinephrine; norepinephrine]
<Options>: A: norepinephrine glucuronide
B: metanephrine
C: adrenalone
D: ethylnorepinephrine
E: noradrenalone
F: norphenylephrine (aka norfenefrine)
G: norepinephrine, (+)-isomer (aka norepinephrine)
H: norsynephrine (aka octopamine)
I: None of the above. | [I; G] |
<Instruct>: Given the context 'Stimulus-induced fractional overflow of neurotransmitter from the epinephrine-treated kidneys was approximately twice normal and consisted of both norepinephrine and epinephrine in proportions similar to those found in the kidney.', select the correct biomedical concept for each mention u... | <Mentions>: [epinephrine; norepinephrine]
<Options>: A: adrenaline (aka epinephrine)
B: metanephrine
C: norphenylephrine (aka norfenefrine)
D: noradrenaline (aka norepinephrine)
E: ethylphenylephrine (aka etilefrine)
F: adrenergic (aka adrenergic agents)
G: norephrine (aka nordefrin)
H: levorine (aka candicidin)
I: epi... | [A; D] |
<Instruct>: Given the context 'Propranolol had no effect on stimulus-induced overflow in either group.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [propranolol]
<Options>: A: propranolol fd
B: propranolol hydrochloride (aka propranolol)
C: proclonol
D: propine (aka dipivefrin)
E: chlorpropanol (aka tobanum)
F: None of the above. | [B] |
<Instruct>: Given the context 'Phentolamine increased stimulus-induced overflow in both groups although the increment in overflow was greater in the epinephrine-treated group.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each menti... | <Mentions>: [phentolamine; epinephrine]
<Options>: A: norsynephrine (aka octopamine)
B: epinephrine
C: norepinephrine
D: norphenylephrine (aka norfenefrine)
E: phenpentermine
F: phenazoline (aka antazoline)
G: methanesulfonate, phentolamine (aka phentolamine)
H: deoxyepinephrine
I: 2-phenylethylamine (aka phenethylamin... | [G; B] |
<Instruct>: Given the context 'Phentolamine increased stimulus-induced overflow in both groups although the increment in overflow was greater in the epinephrine-treated group.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each menti... | <Mentions>: [phentolamine; epinephrine]
<Options>: A: phenamine (aka amphetamine)
B: adrenaline (aka epinephrine)
C: alpha-phenylethylamine (aka 1-phenethylamine)
D: phentolamine
E: phenazoline (aka antazoline)
F: adrenergic (aka adrenergic agents)
G: adrenalone
H: noradrenaline (aka norepinephrine)
I: fenethylline
J: ... | [D; B] |
<Instruct>: Given the context 'In conclusion, chronic epinephrine treatment results in enhanced fractional neurotransmitter overflow.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [epinephrine]
<Options>: A: adrenaline (aka epinephrine)
B: epinemin
C: metanephrine
D: epinephrine, racemic mixture (aka racepinephrine)
E: ethylphenylephrine (aka etilefrine)
F: None of the above. | [A] |
<Instruct>: Given the context 'Furthermore, data obtained with phentolamine alone do not suggest alpha-adrenoceptor desensitization as the cause of the enhanced neurotransmitter overflow after epinephrine treatment.', select the correct biomedical concept for each mention using the provided options. In the answer, list... | <Mentions>: [phentolamine; epinephrine]
<Options>: A: ethylphenylephrine (aka etilefrine)
B: phenylthioethylamine (aka phenyl-2-aminoethyl sulfide)
C: alpha-methylepinephrine
D: ethylnorepinephrine
E: adrenaline (aka epinephrine)
F: phentermine
G: phenamine (aka amphetamine)
H: phentolamine mono-hydrochloride (aka phen... | [H; E] |
<Instruct>: Given the context 'Furthermore, data obtained with phentolamine alone do not suggest alpha-adrenoceptor desensitization as the cause of the enhanced neurotransmitter overflow after epinephrine treatment.', select the correct biomedical concept for each mention using the provided options. In the answer, list... | <Mentions>: [phentolamine; epinephrine]
<Options>: A: alpha-methylepinephrine
B: epinemin
C: phentermine
D: ethylnorepinephrine
E: phenazoline (aka antazoline)
F: phenylthioethylamine (aka phenyl-2-aminoethyl sulfide)
G: phentolamine mono-hydrochloride (aka phentolamine)
H: ethylphenylephrine (aka etilefrine)
I: phenam... | [G; J] |
<Instruct>: Given the context 'Furthermore, data obtained with phentolamine alone do not suggest alpha-adrenoceptor desensitization as the cause of the enhanced neurotransmitter overflow after epinephrine treatment.', select the correct biomedical concept for each mention using the provided options. In the answer, list... | <Mentions>: [phentolamine; epinephrine]
<Options>: A: phenamine (aka amphetamine)
B: phentolamine mesylate (aka phentolamine)
C: epinephrine, racemic mixture (aka racepinephrine)
D: phentermine
E: catecholamine (aka catecholamines)
F: epinemin
G: phenylthioethylamine (aka phenyl-2-aminoethyl sulfide)
H: alpha-methylepi... | [B; J] |
<Instruct>: Given the context 'Even after early detection and prompt treatment, 41% of cases of uveitis did not respond to more than six months of intensive topical treatment with corticosteroids and mydriatics.', select the correct biomedical concept for each mention using the provided options. In the answer, list the... | <Mentions>: [corticosteroids]
<Options>: A: corticosterone
B: glucocorticoids
C: neuro steroids (aka neurosteroids)
D: cardiotonic steroids (aka cardiac glycosides)
E: corticoid (aka adrenal cortex hormones)
F: None of the above. | [E] |
<Instruct>: Given the context 'We used chloroquine or hydroxychloroquine in 173 of 210 cases and found only one case of chorioretinopathy attributable to these drugs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separ... | <Mentions>: [chloroquine; hydroxychloroquine]
<Options>: A: dichloroquine (aka chloroxine)
B: 7-chloro-6-(2-chloroethylamino)-5,8-quinolinequinone
C: chlorquinaldol
D: chloroxoquinoline
E: 7-chloro-4-hydroxyquinoline
F: 5-chlorohydroxyquinol
G: chlorochin (aka chloroquine)
H: n'-(7-chloro-quinolin-4-yl)-n,n-dimethyl-et... | [G; I] |
<Instruct>: Given the context 'We used chloroquine or hydroxychloroquine in 173 of 210 cases and found only one case of chorioretinopathy attributable to these drugs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separ... | <Mentions>: [chloroquine; hydroxychloroquine]
<Options>: A: chlorchinaldine (aka chlorquinaldol)
B: chlorochin (aka chloroquine)
C: cdhq (aka 2-chloro-7,8-dihydro-7,8-dihydroxyquinoline)
D: chloroquine diorotate
E: 7-chloro-4-hydroxyquinoline
F: hydroxychlorochin (aka hydroxychloroquine)
G: 5-chloro-8-hydroxyquinoline
... | [B; F] |
<Instruct>: Given the context 'Systemically administered corticosteroids were used in 75 of 210 cases; a significant number of posterior subcapsular cataracts was found.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, se... | <Mentions>: [corticosteroids]
<Options>: A: steroid (aka steroids)
B: neuro steroid (aka neurosteroids)
C: corticosterone
D: glucocorticoids
E: cortex hormone, adrenal (aka adrenal cortex hormones)
F: None of the above. | [E] |
<Instruct>: Given the context 'Water intoxication associated with oxytocin administration during saline-induced abortion.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [oxytocin]
<Options>: A: oxytocin
B: oxytocin, arginine (aka vasotocin)
C: pro-oxytocin (aka oxytocin, gly-lys-arg-)
D: oxytocic (aka oxytocics)
E: oxytocin, tryptophan(2)- (aka oxytocin, trp(2)-)
F: None of the above. | [A] |
<Instruct>: Given the context 'Four cases of water intoxication in connection with oxytocin administration during saline-induced abortions are described.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semic... | <Mentions>: [oxytocin]
<Options>: A: oxytocin
B: arginine oxytocin (aka vasotocin)
C: oxytocin, glutamic acid(4)- (aka oxytocin, glu(4)-)
D: oxytocin, 8-l-isoleucine- (aka mesotocin)
E: oxytocic (aka oxytocics)
F: None of the above. | [A] |
<Instruct>: Given the context 'Four cases of water intoxication in connection with oxytocin administration during saline-induced abortions are described.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semic... | <Mentions>: [oxytocin]
<Options>: A: oxytocin, 8-l-isoleucine- (aka mesotocin)
B: oxytocin, glutamic acid(4)- (aka oxytocin, glu(4)-)
C: oxytocic (aka oxytocics)
D: arginine oxytocin (aka vasotocin)
E: None of the above. | [E] |
<Instruct>: Given the context 'Oxytocin administration during midtrimester-induced abortions is advocated only if it can be carried out under careful observations of an alert nursing staff, aware of the symptoms of water intoxication and instructed to watch the diuresis and report such early signs of the syndrome as as... | <Mentions>: [oxytocin]
<Options>: A: oxytocin, tryptophan(2)- (aka oxytocin, trp(2)-)
B: oxytocin, gly(4)-
C: oxytocin
D: oxytocin, glu(nhnh2)(4)-
E: oxytocin, 8-l-isoleucine- (aka mesotocin)
F: None of the above. | [C] |
<Instruct>: Given the context 'The oxytocin should be given only in Ringers lactate or, alternately, in Ringers lactate and a 5 per cent dextrose and water solutions.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separ... | <Mentions>: [oxytocin; lactate; dextrose]
<Options>: A: oxytocin, 5-l-aspartic acid- (aka oxytocin, asp(5)-)
B: glyceryl lactate
C: ethyl lactate, (r)-isomer (aka ethyl lactate)
D: l-glucose (aka glucose, (l)-isomer)
E: d-glucose, o-d-glucopyranosyl
F: d glucose (aka glucose)
G: oxytocin
H: oxytocin, histidine(4)- (aka... | [G; O; F] |
<Instruct>: Given the context 'The oxytocin should be given only in Ringers lactate or, alternately, in Ringers lactate and a 5 per cent dextrose and water solutions.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separ... | <Mentions>: [oxytocin; lactate; dextrose]
<Options>: A: 1-deoxy-d-glucose (aka 1,5-anhydroglucitol)
B: oxytocin, glu(nhnh2)(4)-
C: glyceryl lactate
D: dextrose (aka glucose)
E: sugar (aka sugars)
F: oxytocic (aka oxytocics)
G: oxytocin
H: oxytocin, 5-l-aspartic acid- (aka oxytocin, asp(5)-)
I: 2-deoxy-d-glucose (aka de... | [G; N; D] |
<Instruct>: Given the context 'The oxytocin should be given only in Ringers lactate or, alternately, in Ringers lactate and a 5 per cent dextrose and water solutions.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separ... | <Mentions>: [oxytocin; lactate; dextrose]
<Options>: A: oxytocin, 2-(3-hydroxy-l-tyrosine)- (aka oxytocin, 2-l-dopa-)
B: oxytocin, histidine(4)- (aka oxytocin, his(4)-)
C: lactic acid
D: sodium lactate
E: lactates
F: ethyl lactate, (r)-isomer (aka ethyl lactate)
G: oxytocin
H: l-glucose (aka glucose, (l)-isomer)
I: oxy... | [G; C; M] |
<Instruct>: Given the context 'The oxytocin should be given only in Ringers lactate or, alternately, in Ringers lactate and a 5 per cent dextrose and water solutions.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separ... | <Mentions>: [oxytocin; lactate; dextrose]
<Options>: A: oxytocin, glu(nhnh2)(4)-
B: glucitol (aka sorbitol)
C: lactates
D: lactic acid
E: l-glucose (aka glucose, (l)-isomer)
F: 1-deoxy-d-glucose (aka 1,5-anhydroglucitol)
G: oxytocin, histidine(4)- (aka oxytocin, his(4)-)
H: glucose, (alpha-d)-isomer (aka glucose)
I: gl... | [O; D; H] |
<Instruct>: Given the context 'The urinary output should be monitored and the oxytocin administration discontinued and the serum electrolytes checked if the urinary output decreases.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for eac... | <Mentions>: [oxytocin]
<Options>: A: precursor-oxytocin (aka oxytocin, gly-lys-arg-)
B: oxytocin
C: oxytocin, hydroxy-threonine(4)- (aka oxytocin, hydroxy-thr(4)-)
D: oxytocin, arginine (aka vasotocin)
E: oxytocin, glu(4)-
F: None of the above. | [B] |
<Instruct>: Given the context 'The oxytocin should not be administered in excess of 36 hours.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon. | <Mentions>: [oxytocin]
<Options>: A: oxytocin, 5-l-aspartic acid- (aka oxytocin, asp(5)-)
B: oxytocin
C: oxytocin, glu(nhnh2)(4)-
D: oxytocin, gly(4)-
E: oxytocin, 8-l-tryptophan- (aka oxytocin, trp(8)-)
F: None of the above. | [B] |
<Instruct>: Given the context 'If the patient has not aborted by then the oxytocin should be discontinued for 10 to 12 hours in order to perform electrolyte determinations and correct any electrolyte imbalance.', select the correct biomedical concept for each mention using the provided options. In the answer, list the ... | <Mentions>: [oxytocin]
<Options>: A: oxytocin
B: oxytocin, glu(nhnh2)(4)-
C: oxytocin, glu(4)-
D: pro-oxytocin (aka oxytocin, gly-lys-arg-)
E: oxytocic (aka oxytocics)
F: None of the above. | [A] |
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