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gnormplus-classification

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query
string
positive
list
negative
list
system
string
What is the biomedical concept corresponding to 'mct-1'?
[ "mct-1 (homo sapiens)" ]
[ "slc16a1 (homo sapiens)", "mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))", "slc16a3 (homo sapiens)", "mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))" ]
Given the context 'We termed this novel gene with multiple copies in a T-cell malignancy as MCT-1.', answer the user's query.
What is the biomedical concept corresponding to 'mct-1'?
[ "mct-1 (homo sapiens)" ]
[ "slc16a1 (homo sapiens)", "mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))", "slc16a3 (homo sapiens)", "mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))" ]
Given the context 'MCT-1 was localized to the long arm of chromosome Xq22-24 by flourescence in situ hybridization analysis.', answer the user's query.
What is the biomedical concept corresponding to 'cyclin h'?
[ "cyclin h (homo sapiens)", "ccnh (homo sapiens)", "p34 (homo sapiens) (cyclin h (homo sapiens))", "p37 (homo sapiens) (cyclin h (homo sapiens))" ]
[ "cyclin c (homo sapiens)", "ccnc (homo sapiens)", "cyclin h (gallus gallus)", "ccng (homo sapiens)" ]
Given the context 'Although there was no significant homology at the primary sequence level, there was a limited degree of amino acid homology with a domain of cyclin H that appears to specify protein-protein complexes.', answer the user's query.
What is the biomedical concept corresponding to 'mct-1'?
[ "mct-1 (homo sapiens)" ]
[ "slc16a1 (homo sapiens)", "mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))", "slc16a3 (homo sapiens)", "mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))" ]
Given the context 'This relationship between MCT-1 and cyclin H implied a potential role for MCT-1 in cell cycle regulation.', answer the user's query.
What is the biomedical concept corresponding to 'cyclin h'?
[ "cyclin h (homo sapiens)", "ccnh (homo sapiens)", "p34 (homo sapiens) (cyclin h (homo sapiens))", "p37 (homo sapiens) (cyclin h (homo sapiens))" ]
[ "cyclin c (homo sapiens)", "ccnc (homo sapiens)", "cyclin h (gallus gallus)", "ccng (homo sapiens)" ]
Given the context 'This relationship between MCT-1 and cyclin H implied a potential role for MCT-1 in cell cycle regulation.', answer the user's query.
What is the biomedical concept corresponding to 'mct-1'?
[ "mct-1 (homo sapiens)" ]
[ "slc16a1 (homo sapiens)", "mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))", "slc16a3 (homo sapiens)", "mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))" ]
Given the context 'This relationship between MCT-1 and cyclin H implied a potential role for MCT-1 in cell cycle regulation.', answer the user's query.
What is the biomedical concept corresponding to 'mct-1'?
[ "mct-1 (homo sapiens)" ]
[ "slc16a1 (homo sapiens)", "mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))", "slc16a3 (homo sapiens)", "mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))" ]
Given the context 'Overexpression of MCT-1 increased the proliferative rate of cells by decreasing the length of the G1 phase without a reciprocal increase in the S and G2-M phases.', answer the user's query.
What is the biomedical concept corresponding to 'mct-1'?
[ "mct-1 (homo sapiens)" ]
[ "slc16a1 (homo sapiens)", "mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))", "slc16a3 (homo sapiens)", "mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))" ]
Given the context 'Therefore, we investigated the transforming ability of MCT-1 overexpression using soft agar growth assays and demonstrated that only MCT-1-overexpressing cells were able to establish colonies.', answer the user's query.
What is the biomedical concept corresponding to 'mct-1'?
[ "mct-1 (homo sapiens)" ]
[ "slc16a1 (homo sapiens)", "mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))", "slc16a3 (homo sapiens)", "mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))" ]
Given the context 'Therefore, we investigated the transforming ability of MCT-1 overexpression using soft agar growth assays and demonstrated that only MCT-1-overexpressing cells were able to establish colonies.', answer the user's query.
What is the biomedical concept corresponding to 'mct-1'?
[ "mct-1 (homo sapiens)" ]
[ "slc16a1 (homo sapiens)", "mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))", "slc16a3 (homo sapiens)", "mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))" ]
Given the context 'Taken together, MCT-1 is a novel candidate oncogene with homology to a protein-protein binding domain of cyclin H.', answer the user's query.
What is the biomedical concept corresponding to 'cyclin h'?
[ "cyclin h (homo sapiens)", "ccnh (homo sapiens)", "p34 (homo sapiens) (cyclin h (homo sapiens))", "p37 (homo sapiens) (cyclin h (homo sapiens))" ]
[ "cyclin c (homo sapiens)", "ccnc (homo sapiens)", "cyclin h (gallus gallus)", "ccng (homo sapiens)" ]
Given the context 'Taken together, MCT-1 is a novel candidate oncogene with homology to a protein-protein binding domain of cyclin H.', answer the user's query.
What is the biomedical concept corresponding to 'akr1c3'?
[ "akr1c3 (homo sapiens)" ]
[ "akr1c2 (homo sapiens)", "akr1c1 (homo sapiens)", "akr1c3 (sus scrofa)", "akr6a3 (homo sapiens)" ]
Given the context 'Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity. ', answer the user's query.
What is the biomedical concept corresponding to 'akr1c3'?
[ "akr1c3 (homo sapiens)" ]
[ "akr1c2 (homo sapiens)", "akr1c1 (homo sapiens)", "akr1c3 (sus scrofa)", "akr6a3 (homo sapiens)" ]
Given the context 'The properties of AKR1C3 have not been fully characterized compared to the other isoforms.', answer the user's query.
What is the biomedical concept corresponding to 'akr1c3'?
[ "akr1c3 (homo sapiens)" ]
[ "akr1c2 (homo sapiens)", "akr1c1 (homo sapiens)", "akr1c3 (sus scrofa)", "akr6a3 (homo sapiens)" ]
Given the context 'In addition, a cDNA that shows more than 99% homology with AKR1C3 cDNA has been cloned from human myeloblasts.', answer the user's query.
What is the biomedical concept corresponding to 'akr1c3'?
[ "akr1c3 (homo sapiens)" ]
[ "akr1c2 (homo sapiens)", "akr1c1 (homo sapiens)", "akr1c3 (sus scrofa)", "akr6a3 (homo sapiens)" ]
Given the context 'The recombinant AKR1C3 prepared by site-directed mutagenesis of DBDH also showed the same properties as the wild-type DBDH.', answer the user's query.
What is the biomedical concept corresponding to 'akr1c3'?
[ "akr1c3 (homo sapiens)" ]
[ "akr1c2 (homo sapiens)", "akr1c1 (homo sapiens)", "akr1c3 (sus scrofa)", "akr6a3 (homo sapiens)" ]
Given the context 'Analyses of expression of mRNAs for DBDH and AKR1C3 by reverse transcription-PCR indicated that only one mRNA species for DBDH is expressed in 33 human specimens of liver, kidney, lung, brain, heart, spleen, adrenal gland, small intestine, placenta, prostate, and testis.', answer the user's query.
What is the biomedical concept corresponding to 'akr1c3'?
[ "akr1c3 (homo sapiens)" ]
[ "akr1c2 (homo sapiens)", "akr1c1 (homo sapiens)", "akr1c3 (sus scrofa)", "akr6a3 (homo sapiens)" ]
Given the context 'These results suggest that AKR1C3 acts as prostaglandin D2 11-ketoreductase, and that its principal gene in the human has a coding region represented by DBDH cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'hakr e'?
[ "hakre (homo sapiens)", "hakrb (homo sapiens)" ]
[ "hakrc (homo sapiens)", "hakra (homo sapiens)", "ackr3 (homo sapiens)", "hbrek (homo sapiens)" ]
Given the context 'In this study, we have identified a previously unclassified aldoketoreductase family member (termed HAKR e) that is expressed in HL60 cells.', answer the user's query.
What is the biomedical concept corresponding to 'hakr e'?
[ "hakre (homo sapiens)", "hakrb (homo sapiens)" ]
[ "hakrc (homo sapiens)", "hakra (homo sapiens)", "ackr3 (homo sapiens)", "hbrek (homo sapiens)" ]
Given the context 'HAKR e is dramatically and transiently up-regulated in HL60 cells within 24 h of exposure to ATRA, further supporting the proposition that a member(s) of this family of enzymes play(s) a role in controlling cell growth and/or differentiation.', answer the user's query.
What is the biomedical concept corresponding to 'bradykinin'?
[ "bk (homo sapiens)" ]
[ "kallikrein b1 (homo sapiens)", "bradykinin (xenopus tropicalis)", "kallikrein b1 (bos taurus)", "bradykinin receptor b1 (homo sapiens)" ]
Given the context 'G protein-coupled receptors such as the receptors for bradykinin are present in low copy numbers in most natural cells.', answer the user's query.
What is the biomedical concept corresponding to 'b1 receptor'?
[ "b1r (homo sapiens)", "bradykinin receptor b1 (homo sapiens)", "bkb1r (homo sapiens)", "b1bkr (homo sapiens)" ]
[ "b1ar (homo sapiens)", "adrb1r (homo sapiens)", "adhesion g protein-coupled receptor b1 (homo sapiens)", "npbwr1 (bos taurus)" ]
Given the context 'The B1 receptor failed to undergo ligand-induced phosphorylation.', answer the user's query.
What is the biomedical concept corresponding to 'b2 receptor'?
[ "b2r (homo sapiens)", "bradykinin receptor b2 (homo sapiens)", "bkr2 (homo sapiens)", "bdkrb2 (homo sapiens)" ]
[ "b2ar (homo sapiens)", "adrb2r (homo sapiens)", "bkb1r (homo sapiens)", "bb2r (homo sapiens)" ]
Given the context 'However the B2 receptor showed selective phosphorylation of a minor 38 kDa band and lack of phosphorylation of a dominant 33 kDa band, indicating that only a fraction of the receptor protein is functionally linked to the kinase pathway.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'Isolation of hMRE11B: failure to complement yeast mre11 defects due to species-specific protein interactions. ', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'We present the isolation of hMRE11B cDNA from a human HeLa cell cDNA library as an MRE11 homolog.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'Compared to the previously identified hMRE11, hMRE11B contains an additional 84bp sequence that results in a 28 amino-acid insertion close to the C-terminus.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'The expression pattern of hMRE11B in different tissues shows the presence of two mRNA species of approx.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'Overexpression of hMRE11B does not complement the alkylation sensitivity of the mre11 null and temperature-sensitive mutant strains.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'First, both Northern and Western analyses rule out the lack of hMRE11B transcription and/or translation in yeast.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'Second, we demonstrate that hMre11B, like the yeast Mre11 protein, dimerizes in vivo in a yeast two-hybrid system.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'This dimerization requires the C-terminal one-third of hMre11B protein, which includes the 28 amino acids absent in hMre11.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', answer the user's query.
What is the biomedical concept corresponding to 'rad50'?
[ "rad50 (saccharomyces cerevisiae s288c)" ]
[ "rad50 (homo sapiens)", "rad50 homolog, double strand break repair protein (xenopus tropicalis)", "rad50 double strand break repair protein (homo sapiens)", "rad50 (drosophila melanogaster)" ]
Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', answer the user's query.
What is the biomedical concept corresponding to 'xrs2'?
[ "xrs2 (saccharomyces cerevisiae s288c)", "xrs2p (saccharomyces cerevisiae s288c)" ]
[ "x-ray repair cross complementing 2 (drosophila melanogaster)", "xrp2 (homo sapiens)", "xrg2 (homo sapiens)", "xrn2 (homo sapiens)" ]
Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', answer the user's query.
What is the biomedical concept corresponding to 'rad50'?
[ "rad50 (saccharomyces cerevisiae s288c)" ]
[ "rad50 (homo sapiens)", "rad50 homolog, double strand break repair protein (xenopus tropicalis)", "rad50 double strand break repair protein (homo sapiens)", "rad50 (drosophila melanogaster)" ]
Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', answer the user's query.
What is the biomedical concept corresponding to 'xrs2'?
[ "xrs2 (saccharomyces cerevisiae s288c)", "xrs2p (saccharomyces cerevisiae s288c)" ]
[ "x-ray repair cross complementing 2 (drosophila melanogaster)", "xrp2 (homo sapiens)", "xrg2 (homo sapiens)", "xrn2 (homo sapiens)" ]
Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'We rule out the hypothesis that the lack of interaction and, in turn of complementation, is due to the absence of sequence homology at the C-terminal domain of hMre11B compared to the yeast Mre11.', answer the user's query.
What is the biomedical concept corresponding to 'hmre11b'?
[ "hmre11b (homo sapiens)" ]
[ "olfactory receptor family 11 subfamily h member 4b (mus musculus)", "or11h4b (mus musculus)", "or2h1b (mus musculus)", "or4c11b (mus musculus)" ]
Given the context 'Instead, we propose that the C-terminus of hMre11B participates in protein-protein interaction and functions in a species-specific manner.', answer the user's query.