query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'hai-2'? | [
"hai-2 (homo sapiens)",
"hai2 (homo sapiens)",
"serine peptidase inhibitor, kunitz type 2 (homo sapiens)"
] | [
"itih2 (homo sapiens)",
"hcinf2 (homo sapiens)",
"inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens)",
"iti-hc2 (homo sapiens)"
] | Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', answer the user's query. |
What is the biomedical concept corresponding to 'hai-1'? | [
"hai1 (homo sapiens)",
"hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens))"
] | [
"hait1 (homo sapiens)",
"haip1 (homo sapiens)",
"hai-2 (homo sapiens)",
"hai2 (homo sapiens)"
] | Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', answer the user's query. |
What is the biomedical concept corresponding to 'hai-2'? | [
"hai-2 (homo sapiens)",
"hai2 (homo sapiens)",
"serine peptidase inhibitor, kunitz type 2 (homo sapiens)"
] | [
"itih2 (homo sapiens)",
"hcinf2 (homo sapiens)",
"inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens)",
"iti-hc2 (homo sapiens)"
] | Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', answer the user's query. |
What is the biomedical concept corresponding to 'hai-2'? | [
"hai-2 (homo sapiens)",
"hai2 (homo sapiens)",
"serine peptidase inhibitor, kunitz type 2 (homo sapiens)"
] | [
"itih2 (homo sapiens)",
"hcinf2 (homo sapiens)",
"inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens)",
"iti-hc2 (homo sapiens)"
] | Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'hai-1'? | [
"hai1 (homo sapiens)",
"hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens))"
] | [
"hait1 (homo sapiens)",
"haip1 (homo sapiens)",
"hai-2 (homo sapiens)",
"hai2 (homo sapiens)"
] | Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'hgf activator'? | [
"hgf activator (homo sapiens)",
"hgfa (homo sapiens)",
"hgfac (homo sapiens)"
] | [
"hepatocyte growth factor activator (mus musculus)",
"hgf (homo sapiens) (hepatocyte growth factor (homo sapiens))",
"hepatocyte growth factor (homo sapiens)",
"hgfal (homo sapiens)"
] | Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'hgf'? | [
"hepatocyte growth factor (homo sapiens)",
"hgf (homo sapiens) (hepatocyte growth factor (homo sapiens))",
"sf (homo sapiens) (hepatocyte growth factor (homo sapiens))"
] | [
"hgfa (homo sapiens)",
"hgf (homo sapiens) (interleukin 6 (homo sapiens))",
"hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens))",
"hgf activator (homo sapiens)"
] | Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'glycogenin-2'? | [
"glycogenin 2 (homo sapiens)"
] | [
"glycogenin 2 (xenopus tropicalis)",
"glycogen synthase 2 (homo sapiens)",
"glycogenin 2 (gallus gallus)",
"glycogenin 1 (homo sapiens)"
] | Given the context 'Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis.
', answer the user's query. |
What is the biomedical concept corresponding to 'glycogenin-2'? | [
"glycogenin 2 (homo sapiens)"
] | [
"glycogenin 2 (xenopus tropicalis)",
"glycogen synthase 2 (homo sapiens)",
"glycogenin 2 (gallus gallus)",
"glycogenin 1 (homo sapiens)"
] | Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"gnl2 (homo sapiens)",
"gngt2 (homo sapiens)",
"gng2 (homo sapiens)",
"gnp2 (homo sapiens)"
] | Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', answer the user's query. |
What is the biomedical concept corresponding to 'glycogenin-2'? | [
"glycogenin 2 (homo sapiens)"
] | [
"glycogenin 2 (xenopus tropicalis)",
"glycogen synthase 2 (homo sapiens)",
"glycogenin 2 (gallus gallus)",
"glycogenin 1 (homo sapiens)"
] | Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2alpha'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"gnai2a (homo sapiens)",
"gnl2 (homo sapiens)",
"gnai2 (homo sapiens)",
"gnat2 (homo sapiens)"
] | Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2beta'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"gnl2 (homo sapiens)",
"gnb2 (homo sapiens)",
"gngt2 (homo sapiens)",
"gnat2 (homo sapiens)"
] | Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2gamma'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"g protein subunit gamma 2 (homo sapiens)",
"g protein subunit gamma transducin 2 (homo sapiens)",
"gng2 (homo sapiens)",
"gngt2 (homo sapiens)"
] | Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"gnl2 (homo sapiens)",
"gngt2 (homo sapiens)",
"gng2 (homo sapiens)",
"gnp2 (homo sapiens)"
] | Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', answer the user's query. |
What is the biomedical concept corresponding to 'muscle glycogenin'? | [
"glycogenin 1 (homo sapiens)"
] | [
"glycogenin 1 (mus musculus)",
"glycogenin-1 (gallus gallus)",
"glycogenin 1 (gallus gallus)",
"muscle glycogen phosphorylase (mus musculus)"
] | Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"gnl2 (homo sapiens)",
"gngt2 (homo sapiens)",
"gng2 (homo sapiens)",
"gnp2 (homo sapiens)"
] | Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"gnl2 (homo sapiens)",
"gngt2 (homo sapiens)",
"gng2 (homo sapiens)",
"gnp2 (homo sapiens)"
] | Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', answer the user's query. |
What is the biomedical concept corresponding to 'skeletal muscle glycogen synthase'? | [
"glycogen synthase 1 (homo sapiens)"
] | [
"glycogen synthase 1, muscle (mus musculus)",
"glycogen synthase 2 (mus musculus)",
"glycogen synthase 1 (muscle) (gallus gallus)",
"glycogen synthase 2 (homo sapiens)"
] | Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"gnl2 (homo sapiens)",
"gngt2 (homo sapiens)",
"gng2 (homo sapiens)",
"gnp2 (homo sapiens)"
] | Given the context 'Antibodies raised against GN-2 produced in E. coli recognized proteins of Mr approximately 66,000 present in extracts of rat liver and in cultured H4IIEC3 hepatoma cells.', answer the user's query. |
What is the biomedical concept corresponding to 'gn-2'? | [
"gn-2 (homo sapiens)",
"gn2 (homo sapiens)"
] | [
"gnl2 (homo sapiens)",
"gngt2 (homo sapiens)",
"gng2 (homo sapiens)",
"gnp2 (homo sapiens)"
] | Given the context 'In H4IIEC3 cells, most of the GN-2 was present as a free protein but some was covalently associated with glycogen fractions and was only released by treatment with alpha-amylase.', answer the user's query. |
What is the biomedical concept corresponding to 'muscle form of glycogenin'? | [
"glycogenin 1 (homo sapiens)"
] | [
"glycogenin 1 (mus musculus)",
"muscle glycogen phosphorylase (mus musculus)",
"glycogen synthase 1, muscle (mus musculus)",
"glycogenin-1 (gallus gallus)"
] | Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', answer the user's query. |
What is the biomedical concept corresponding to 'glycogenin-1'? | [
"glycogenin 1 (homo sapiens)"
] | [
"glycogenin-1 (caenorhabditis elegans)",
"glycogenin 1 (xenopus tropicalis)",
"glycogen synthase 1 (homo sapiens)",
"glycogenin-1 (gallus gallus)"
] | Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', answer the user's query. |
What is the biomedical concept corresponding to 'hsk4'? | [
"hsk4 (homo sapiens)"
] | [
"mapkk4 (homo sapiens)",
"hbk4 (homo sapiens)",
"stk4 (homo sapiens)",
"ysk4 (homo sapiens)"
] | Given the context 'hSK4, a member of a novel subfamily of calcium-activated potassium channels.
', answer the user's query. |
What is the biomedical concept corresponding to 'hsk4'? | [
"hsk4 (homo sapiens)"
] | [
"mapkk4 (homo sapiens)",
"hbk4 (homo sapiens)",
"stk4 (homo sapiens)",
"ysk4 (homo sapiens)"
] | Given the context 'The gene for hSK4, a novel human small conductance calcium-activated potassium channel, or SK channel, has been identified and expressed in Chinese hamster ovary cells.', answer the user's query. |
What is the biomedical concept corresponding to 'hsk4'? | [
"hsk4 (homo sapiens)"
] | [
"mapkk4 (homo sapiens)",
"hbk4 (homo sapiens)",
"stk4 (homo sapiens)",
"ysk4 (homo sapiens)"
] | Given the context 'In physiological saline hSK4 generates a conductance of approximately 12 pS, a value in close agreement with that of other cloned SK channels.', answer the user's query. |
What is the biomedical concept corresponding to 'hsk4'? | [
"hsk4 (homo sapiens)"
] | [
"mapkk4 (homo sapiens)",
"hbk4 (homo sapiens)",
"stk4 (homo sapiens)",
"ysk4 (homo sapiens)"
] | Given the context 'Like other members of this family, the polypeptide encoded by hSK4 contains a previously unnoted leucine zipper-like domain in its C terminus of unknown function.', answer the user's query. |
What is the biomedical concept corresponding to 'hsk4'? | [
"hsk4 (homo sapiens)"
] | [
"mapkk4 (homo sapiens)",
"hbk4 (homo sapiens)",
"stk4 (homo sapiens)",
"ysk4 (homo sapiens)"
] | Given the context 'hSK4 appears unique, however, in its very high affinity for Ca2+ (EC50 of 95 nM) and its predominant expression in nonexcitable tissues of adult animals.', answer the user's query. |
What is the biomedical concept corresponding to 'hsk4'? | [
"hsk4 (homo sapiens)"
] | [
"mapkk4 (homo sapiens)",
"hbk4 (homo sapiens)",
"stk4 (homo sapiens)",
"ysk4 (homo sapiens)"
] | Given the context 'Together with the relatively low homology of hSK4 to other SK channel polypeptides (approximately 40% identical), these data suggest that hSK4 belongs to a novel subfamily of SK channels.', answer the user's query. |
What is the biomedical concept corresponding to 'hsk4'? | [
"hsk4 (homo sapiens)"
] | [
"mapkk4 (homo sapiens)",
"hbk4 (homo sapiens)",
"stk4 (homo sapiens)",
"ysk4 (homo sapiens)"
] | Given the context 'Together with the relatively low homology of hSK4 to other SK channel polypeptides (approximately 40% identical), these data suggest that hSK4 belongs to a novel subfamily of SK channels.', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf/il-3/il-5 receptor common beta chain'? | [
"colony stimulating factor 2 receptor subunit beta (homo sapiens)",
"il5rb (homo sapiens)",
"csf2rb (homo sapiens)",
"il3rb (homo sapiens)"
] | [
"colony stimulating factor 3 receptor (homo sapiens)",
"il5r (homo sapiens)",
"interleukin 2 receptor subunit beta (homo sapiens)",
"csf3r (homo sapiens)"
] | Given the context 'Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression.
', answer the user's query. |
What is the biomedical concept corresponding to 'surfactant protein (sp)-b'? | [
"surfactant protein b (homo sapiens)",
"sp-b (homo sapiens)",
"sftpb (homo sapiens)"
] | [
"surfactant protein b (sus scrofa)",
"surfactant protein b (bos taurus)",
"sp-b (sus scrofa)",
"sftp1b (homo sapiens) (surfactant protein a2 (homo sapiens))"
] | Given the context 'In some cases congenital PAP is associated with hereditary surfactant protein (SP)-B deficiency.', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf/il-3/il-5 receptor common beta chain'? | [
"colony stimulating factor 2 receptor subunit beta (homo sapiens)",
"il5rb (homo sapiens)",
"csf2rb (homo sapiens)",
"il3rb (homo sapiens)"
] | [
"colony stimulating factor 3 receptor (homo sapiens)",
"il5r (homo sapiens)",
"interleukin 2 receptor subunit beta (homo sapiens)",
"csf3r (homo sapiens)"
] | Given the context 'In mice, PAP has been generated by targeted deletion of the genes for either the GM-CSF/IL-3/IL-5 receptor common beta chain (beta c) or GM-CSF.', answer the user's query. |
What is the biomedical concept corresponding to 'quinolinate phosphoribosyltransferase'? | [
"quinolinate phosphoribosyltransferase (homo sapiens)"
] | [
"quinolinate phosphoribosyltransferase (xenopus tropicalis)",
"quinolinate phosphoribosyltransferase (bos taurus)",
"quinolinate phosphoribosyltransferase (sus scrofa)",
"quinolinate phosphoribosyltransferase (rattus norvegicus)"
] | Given the context 'Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase.
', answer the user's query. |
What is the biomedical concept corresponding to 'quinolinate phosphoribosyltransferase'? | [
"quinolinate phosphoribosyltransferase (homo sapiens)"
] | [
"quinolinate phosphoribosyltransferase (xenopus tropicalis)",
"quinolinate phosphoribosyltransferase (bos taurus)",
"quinolinate phosphoribosyltransferase (sus scrofa)",
"quinolinate phosphoribosyltransferase (rattus norvegicus)"
] | Given the context 'Mammalian quinolinate phosphoribosyltransferase (QPRTase) (EC 2.4.2.19) is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway.', answer the user's query. |
What is the biomedical concept corresponding to 'qprtase'? | [
"qprt (homo sapiens)",
"quinolinate phosphoribosyltransferase (homo sapiens)"
] | [
"qprtase (mus musculus)",
"qprt (xenopus tropicalis)",
"quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655)",
"qprt (xenopus laevis)"
] | Given the context 'Mammalian quinolinate phosphoribosyltransferase (QPRTase) (EC 2.4.2.19) is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway.', answer the user's query. |
What is the biomedical concept corresponding to 'qprtase'? | [
"qprt (homo sapiens)",
"quinolinate phosphoribosyltransferase (homo sapiens)"
] | [
"qprtase (mus musculus)",
"qprt (xenopus tropicalis)",
"quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655)",
"qprt (xenopus laevis)"
] | Given the context 'As the first step to elucidate molecular basis underlying the quinolinate metabolism, the cDNA encoding human brain QPRTase was cloned and characterized.', answer the user's query. |
What is the biomedical concept corresponding to 'qprtase'? | [
"quinolinate phosphoribosyltransferase (sus scrofa)"
] | [
"qprt (homo sapiens)",
"qprtase (mus musculus)",
"quinolinate phosphoribosyltransferase (homo sapiens)",
"qprt (xenopus tropicalis)"
] | Given the context 'Utilizing partial amino acid sequences obtained from highly purified porcine kidney QPRTase, a human isolog was obtained from a human brain cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'qprtase'? | [
"qprt (homo sapiens)",
"quinolinate phosphoribosyltransferase (homo sapiens)"
] | [
"qprtase (mus musculus)",
"qprt (xenopus tropicalis)",
"quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655)",
"qprt (xenopus laevis)"
] | Given the context 'To confirm that the cDNA clone encodes human QPRTase, its functional expression was studied in a bacterial host.', answer the user's query. |
What is the biomedical concept corresponding to 'qprtase'? | [
"quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655)"
] | [
"qprt (homo sapiens)",
"qprtase (mus musculus)",
"quinolinate phosphoribosyltransferase (homo sapiens)",
"qprt (xenopus tropicalis)"
] | Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', answer the user's query. |
What is the biomedical concept corresponding to 'nadc'? | [
"nadc (escherichia coli str. k-12 substr. mg1655)"
] | [
"nadc1 (homo sapiens)",
"nadc-1 (homo sapiens)",
"nadc3 (homo sapiens)",
"nadc1 (rattus norvegicus)"
] | Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', answer the user's query. |
What is the biomedical concept corresponding to 'qprtase'? | [
"qprt (homo sapiens)",
"quinolinate phosphoribosyltransferase (homo sapiens)"
] | [
"qprtase (mus musculus)",
"qprt (xenopus tropicalis)",
"quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655)",
"qprt (xenopus laevis)"
] | Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', answer the user's query. |
What is the biomedical concept corresponding to 'qprtase'? | [
"qprt (homo sapiens)",
"quinolinate phosphoribosyltransferase (homo sapiens)"
] | [
"qprtase (mus musculus)",
"qprt (xenopus tropicalis)",
"quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655)",
"qprt (xenopus laevis)"
] | Given the context 'It is concluded that the cloned cDNA encodes human QPRTase which is functional beyond the phylogenic boundary.', answer the user's query. |
What is the biomedical concept corresponding to 'tm4sf5'? | [
"tm4sf5 (homo sapiens)"
] | [
"tm4sf4 (homo sapiens)",
"tm4sf5 (mus musculus)",
"tm4sf10 (homo sapiens)",
"tm4sf5 (sus scrofa)"
] | Given the context 'Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer.
', answer the user's query. |
What is the biomedical concept corresponding to 'tumour-associated antigen l6'? | [
"taal6 (homo sapiens)",
"h-l6 (homo sapiens)",
"l6 (homo sapiens) (transmembrane 4 l six family member 1 (homo sapiens))"
] | [
"mage family member a6 (homo sapiens)",
"magea6 (homo sapiens) (mage family member a6 (homo sapiens))",
"paraneoplastic antigen-like protein 6a (homo sapiens)",
"ribosomal protein l6 (homo sapiens)"
] | Given the context 'In a previous large-scale screening for differentially expressed genes in pancreatic cancer, a gene was identified that was highly overexpressed in pancreatic cancer encoding a novel putative tetraspan transmembrane protein highly homologous to the tumour-associated antigen L6.', answer the user's query. |
What is the biomedical concept corresponding to 'tm4sf5'? | [
"tm4sf5 (homo sapiens)"
] | [
"tm4sf4 (homo sapiens)",
"tm4sf5 (mus musculus)",
"tm4sf10 (homo sapiens)",
"tm4sf5 (sus scrofa)"
] | Given the context 'Using a radiation hybrid panel the identified human gene named TM4SF5 (transmembrane 4 superfamily member 5) was localized to chromosome 17 in the region 17p13.3.', answer the user's query. |
What is the biomedical concept corresponding to 'transmembrane 4 superfamily member 5'? | [
"transmembrane 4 l six family member 5 (homo sapiens)",
"tm4sf5 (homo sapiens)"
] | [
"transmembrane 4 superfamily member 4 (mus musculus)",
"transmembrane 4 superfamily member 5 (mus musculus)",
"transmembrane 4 l six family member 4 (homo sapiens)",
"tetraspanin 4 (homo sapiens)"
] | Given the context 'Using a radiation hybrid panel the identified human gene named TM4SF5 (transmembrane 4 superfamily member 5) was localized to chromosome 17 in the region 17p13.3.', answer the user's query. |
What is the biomedical concept corresponding to 'tm4sf5'? | [
"tm4sf5 (homo sapiens)"
] | [
"tm4sf4 (homo sapiens)",
"tm4sf5 (mus musculus)",
"tm4sf10 (homo sapiens)",
"tm4sf5 (sus scrofa)"
] | Given the context 'The cloned TM4SF5 cDNA has a 32bp 5'-untranslated region (UTR), a 591bp open reading frame (ORF) and a 85bp 3'UTR.', answer the user's query. |
What is the biomedical concept corresponding to 'tm4sf5'? | [
"tm4sf5 (homo sapiens)"
] | [
"tm4sf4 (homo sapiens)",
"tm4sf5 (mus musculus)",
"tm4sf10 (homo sapiens)",
"tm4sf5 (sus scrofa)"
] | Given the context 'The predicted TM4SF5 protein with 197 amino acids contains three NH2-terminal hydrophobic transmembrane regions, followed by an extracellular hydrophilic domain containing two potential N-linked glycosylation sites and a COOH-terminal hydrophobic transmembrane region.', answer the user's query. |
What is the biomedical concept corresponding to 'l6 antigen'? | [
"l6 (homo sapiens) (transmembrane 4 l six family member 1 (homo sapiens))",
"h-l6 (homo sapiens)"
] | [
"l6 (drosophila melanogaster) (lethal (1) l6 (drosophila melanogaster))",
"l6 (homo sapiens) (ribosomal protein l6 (homo sapiens))",
"ribosomal protein l6 (homo sapiens)",
"ribosomal protein l6 pseudogene 6 (homo sapiens)"
] | Given the context 'These structural features are shared by the L6 antigen and a number of related cell surface proteins associated with cell growth.', answer the user's query. |
What is the biomedical concept corresponding to 'tm4sf5'? | [
"tm4sf5 (homo sapiens)"
] | [
"tm4sf4 (homo sapiens)",
"tm4sf5 (mus musculus)",
"tm4sf10 (homo sapiens)",
"tm4sf5 (sus scrofa)"
] | Given the context 'TM4SF5 was overexpressed in pancreatic cancer tissues as compared to both normal pancreas and chronic pancreatitis tissues, and was detected at high levels in other tumour tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'tm4sf5'? | [
"tm4sf5 (homo sapiens)"
] | [
"tm4sf4 (homo sapiens)",
"tm4sf5 (mus musculus)",
"tm4sf10 (homo sapiens)",
"tm4sf5 (sus scrofa)"
] | Given the context 'Although the precise function of TM4SF5 remains to be elucidated it may be useful in a clinical setting for tumour diagnosis and/or therapy.', answer the user's query. |
What is the biomedical concept corresponding to 'l6 antigen'? | [
"l6 (homo sapiens) (transmembrane 4 l six family member 1 (homo sapiens))",
"h-l6 (homo sapiens)"
] | [
"l6 (drosophila melanogaster) (lethal (1) l6 (drosophila melanogaster))",
"l6 (homo sapiens) (ribosomal protein l6 (homo sapiens))",
"ribosomal protein l6 (homo sapiens)",
"ribosomal protein l6 pseudogene 6 (homo sapiens)"
] | Given the context 'This hypothesis is supported by the strong homology to the L6 antigen, which has proved promising in immunological, therapeutic and diagnostic approaches.', answer the user's query. |
What is the biomedical concept corresponding to 'ribosomal protein l14'? | [
"ribosomal protein l14 (homo sapiens)",
"l14 (homo sapiens) (ribosomal protein l14 (homo sapiens))",
"rpl14 (homo sapiens)"
] | [
"l14 (drosophila melanogaster) (ribosomal protein l14 (drosophila melanogaster))",
"mitochondrial ribosomal protein l14 (homo sapiens)",
"60s ribosomal protein l14-like (homo sapiens)",
"ribosomal protein l14 pseudogene (homo sapiens)"
] | Given the context 'Triplet repeat-containing ribosomal protein L14 gene in immortalized human endothelial cell line (t-HUE4).
', answer the user's query. |
What is the biomedical concept corresponding to 'ribosomal subunit protein l14'? | [
"ribosomal protein l14 (homo sapiens)",
"l14 (homo sapiens) (ribosomal protein l14 (homo sapiens))",
"rpl14 (homo sapiens)"
] | [
"60s ribosomal protein l14-like (homo sapiens)",
"mitochondrial ribosomal protein l14 (homo sapiens)",
"l14 (drosophila melanogaster) (ribosomal protein l14 (drosophila melanogaster))",
"ribosomal protein l14 (mus musculus)"
] | Given the context 'A cDNA encoding human 60S ribosomal subunit protein L14 (hRL14) was isolated from a human immortal endothelial cell line, t-HUE4.', answer the user's query. |
What is the biomedical concept corresponding to 'hrl14'? | [
"hrl14 (homo sapiens)",
"rl14 (homo sapiens)",
"rpl14 (homo sapiens)"
] | [
"arl14 (homo sapiens)",
"ribosomal protein l24-like (drosophila melanogaster)",
"bcl2l14 (homo sapiens)",
"rpl14l (homo sapiens)"
] | Given the context 'A cDNA encoding human 60S ribosomal subunit protein L14 (hRL14) was isolated from a human immortal endothelial cell line, t-HUE4.', answer the user's query. |
What is the biomedical concept corresponding to 'hrl14'? | [
"hrl14 (homo sapiens)",
"rl14 (homo sapiens)",
"rpl14 (homo sapiens)"
] | [
"arl14 (homo sapiens)",
"ribosomal protein l24-like (drosophila melanogaster)",
"bcl2l14 (homo sapiens)",
"rpl14l (homo sapiens)"
] | Given the context 'A significant identity for hRL14 was observed with rat RL14 (85% identity), with exception of COOH-terminal region, but not with any eukaryote amino acid sequences so far deposited to database.', answer the user's query. |
What is the biomedical concept corresponding to 'hrl14'? | [
"hrl14 (homo sapiens)",
"rl14 (homo sapiens)",
"rpl14 (homo sapiens)"
] | [
"arl14 (homo sapiens)",
"ribosomal protein l24-like (drosophila melanogaster)",
"bcl2l14 (homo sapiens)",
"rpl14l (homo sapiens)"
] | Given the context 'The typical features of ribosomal proteins were observed in hRL14, as seen in nuclear targeting sequences necessary for the transport from cytoplasm to nucleolus, a bZIP like (basic region-leucine zipper) element for the binding to rRNA, and the internal repeat sequences; the pentapeptide QKA(A/S)X.', answer the user's query. |
What is the biomedical concept corresponding to 'd-dopachrome tautomerase'? | [
"d-dopachrome tautomerase (homo sapiens)"
] | [
"dopachrome tautomerase (homo sapiens)",
"d-dopachrome tautomerase (mus musculus)",
"dopachrome tautomerase (mus musculus)",
"d-dopachrome tautomerase (bos taurus)"
] | Given the context 'Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.
D-Dopachrome tautomerase converts 2-carboxy-2,3-dihydroindole-5,6-quinone (D-dopachrome) into 5,6-dihydroxyindole.', answer the user's query. |
What is the biomedical concept corresponding to 'd-dopachrome tautomerase'? | [
"d-dopachrome tautomerase (homo sapiens)"
] | [
"dopachrome tautomerase (homo sapiens)",
"d-dopachrome tautomerase (mus musculus)",
"dopachrome tautomerase (mus musculus)",
"d-dopachrome tautomerase (bos taurus)"
] | Given the context 'Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.
D-Dopachrome tautomerase converts 2-carboxy-2,3-dihydroindole-5,6-quinone (D-dopachrome) into 5,6-dihydroxyindole.', answer the user's query. |
What is the biomedical concept corresponding to 'macrophage migration inhibitory factor'? | [
"macrophage migration inhibitory factor (homo sapiens)",
"mif (homo sapiens) (macrophage migration inhibitory factor (homo sapiens))",
"mmif (homo sapiens)",
"gif (homo sapiens) (macrophage migration inhibitory factor (homo sapiens))"
] | [
"macrophage migration inhibitory factor (xenopus tropicalis)",
"macrophage migration inhibitory factor (glycosylation-inhibiting factor) (mus musculus)",
"migration and invasion inhibitory protein (homo sapiens)",
"macrophage migration inhibitory factor (caenorhabditis elegans)"
] | Given the context 'This protein has an amino acid sequence that is highly homologous with that of macrophage migration inhibitory factor (MIF), which has the potential to catalyze D-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid and is an important cytokine for T-lymphocyte activation.', answer the user's query. |
What is the biomedical concept corresponding to 'mif'? | [
"mif (homo sapiens) (macrophage migration inhibitory factor (homo sapiens))",
"macrophage migration inhibitory factor (homo sapiens)",
"mmif (homo sapiens)",
"gif (homo sapiens) (macrophage migration inhibitory factor (homo sapiens))"
] | [
"mif1 (homo sapiens)",
"mif-2 (homo sapiens)",
"mif (mus musculus)",
"macrophage migration inhibitory factor (glycosylation-inhibiting factor) (mus musculus)"
] | Given the context 'This protein has an amino acid sequence that is highly homologous with that of macrophage migration inhibitory factor (MIF), which has the potential to catalyze D-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid and is an important cytokine for T-lymphocyte activation.', answer the user's query. |
What is the biomedical concept corresponding to 'd-dopachrome tautomerase'? | [
"d-dopachrome tautomerase (homo sapiens)"
] | [
"dopachrome tautomerase (homo sapiens)",
"d-dopachrome tautomerase (mus musculus)",
"dopachrome tautomerase (mus musculus)",
"d-dopachrome tautomerase (bos taurus)"
] | Given the context 'We isolated and sequenced a 566 bp-long cDNA encoding human D-dopachrome tautomerase.', answer the user's query. |
What is the biomedical concept corresponding to 'd-dopachrome tautomerase'? | [
"d-dopachrome tautomerase (homo sapiens)"
] | [
"dopachrome tautomerase (homo sapiens)",
"d-dopachrome tautomerase (mus musculus)",
"dopachrome tautomerase (mus musculus)",
"d-dopachrome tautomerase (bos taurus)"
] | Given the context 'Northern blot analysis demonstrated that mRNA of D-dopachrome tautomerase is expressed in a large amount in the liver, and to lesser extent in other organs, including the heart, lung and pancreas.', answer the user's query. |
What is the biomedical concept corresponding to 'd-dopachrome tautomerase'? | [
"d-dopachrome tautomerase (homo sapiens)"
] | [
"dopachrome tautomerase (homo sapiens)",
"d-dopachrome tautomerase (mus musculus)",
"dopachrome tautomerase (mus musculus)",
"d-dopachrome tautomerase (bos taurus)"
] | Given the context 'After purification of D-dopachrome tautomerase expressed in E. coli, we confirmed that the recombinant protein catalyzes the conversion of D-dopachrome to 5,6-dihydroxyindole.', answer the user's query. |
What is the biomedical concept corresponding to 'd-dopachrome tautomerase'? | [
"d-dopachrome tautomerase (homo sapiens)"
] | [
"dopachrome tautomerase (homo sapiens)",
"d-dopachrome tautomerase (mus musculus)",
"dopachrome tautomerase (mus musculus)",
"d-dopachrome tautomerase (bos taurus)"
] | Given the context 'Although the precise pathophysiological function of D-dopachrome tautomerase remains to be elucidated, the present results could contribute to further understanding of isomerase activity in relation to the immune response.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'Isolation of full-length cDNA of mouse PAX4 gene and identification of its human homologue.
', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'Recent genetic studies have suggested that PAX4, a member of the paired box (PAX) gene family, is involved in the mechanism regulating the fate of pancreatic islet endocrine progenitor cells.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'Murine PAX4 was originally identified by genomic screening and, to date, only a partial sequence of PAX4 has been reported.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'Murine PAX4 was originally identified by genomic screening and, to date, only a partial sequence of PAX4 has been reported.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'In this study, we cloned the full-length cDNA of mouse PAX4 by RACE (rapid amplification of cDNA ends) using RNA from MIN6 cells, a mouse insulinoma cell line.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'The deduced mouse PAX4 protein was 349 amino acids and had the predicted molecular weight of 38 kDa.', answer the user's query. |
What is the biomedical concept corresponding to 'pax6'? | [
"pax6 (homo sapiens)",
"paired box 6 (homo sapiens)"
] | [
"pax6 (xenopus laevis) (paired box 6 s homeolog (xenopus laevis))",
"paired box protein 6 homolog (gallus gallus)",
"pax6/eye (drosophila melanogaster)",
"paired box protein 6 homolog (caenorhabditis elegans)"
] | Given the context 'Two DNA binding motifs, a 128-amino acid paired domain and a 61-amino acid paired-type homeodomain exhibit the highest amino acid homology with PAX6 (71.2%, 65.0%, respectively), another member of the PAX gene family.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'However, the sequence of the C-terminal segment of PAX4 diverged and showed no significant homology with any other known PAX genes.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'As to the genomic DNA, the coding region of the mouse PAX4 gene spanned approximately 5.5 kb and was composed of 10 exons.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)"
] | [
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)",
"pax4 (xenopus tropicalis)",
"pax-4 (xenopus tropicalis)"
] | Given the context 'In the public DNA database, a human cosmid (g1572c264), which was localized on human chromosome 7q31.3, was found to contain a gene homologous to PAX4.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'The nucleotide and protein sequence homologies between mouse PAX4 and its human homologue were 83.1% and 80.0%, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'adp-ribosylation factor 5'? | [
"arf5 (homo sapiens)",
"arf gtpase 5 (homo sapiens)"
] | [
"adp-ribosylation factor-like 5 (drosophila melanogaster)",
"adp-ribosylation factor-like protein 5 (caenorhabditis elegans)",
"adp ribosylation factor 5 (sus scrofa)",
"adp-ribosyltransferase 5 (homo sapiens)"
] | Given the context 'Interestingly, the ARP5 (ADP-ribosylation factor 5) gene was also found in the same cosmid g1572c264, suggesting the ARP5 gene to be adjacent to the human PAX4 homologue.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)"
] | [
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)",
"pax4 (xenopus tropicalis)",
"pax-4 (xenopus tropicalis)"
] | Given the context 'Interestingly, the ARP5 (ADP-ribosylation factor 5) gene was also found in the same cosmid g1572c264, suggesting the ARP5 gene to be adjacent to the human PAX4 homologue.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax-4 (mus musculus)",
"pax4 (mus musculus)"
] | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)",
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)"
] | Given the context 'The results of this study, i.e. isolation of the full-length cDNA sequence of PAX4 and identification of the homologous human gene, will facilitate further functional and genetic studies of the PAX4 gene.', answer the user's query. |
What is the biomedical concept corresponding to 'pax4'? | [
"pax4 (homo sapiens)",
"paired box 4 (homo sapiens)"
] | [
"paired box protein pax-4 (xenopus laevis)",
"paired box 4 (xenopus tropicalis)",
"pax4 (xenopus tropicalis)",
"pax-4 (xenopus tropicalis)"
] | Given the context 'The results of this study, i.e. isolation of the full-length cDNA sequence of PAX4 and identification of the homologous human gene, will facilitate further functional and genetic studies of the PAX4 gene.', answer the user's query. |
What is the biomedical concept corresponding to 'gsta3'? | [
"gsta3 (homo sapiens)",
"gsta3-3 (homo sapiens)",
"glutathione s-transferase alpha 3 (homo sapiens)"
] | [
"gsta3 (gallus gallus)",
"gstm3 (homo sapiens)",
"gst-iii (homo sapiens)",
"gst-3 (homo sapiens)"
] | Given the context 'Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.
', answer the user's query. |
What is the biomedical concept corresponding to 'gsta4'? | [
"gsta4 (homo sapiens)",
"gsta4-4 (homo sapiens)"
] | [
"gst4 (homo sapiens)",
"gsta4p (homo sapiens)",
"gstt4 (homo sapiens)",
"gstm4 (homo sapiens)"
] | Given the context 'Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.
', answer the user's query. |
What is the biomedical concept corresponding to 'gsta4-4'? | [
"gsta4-4 (homo sapiens)",
"gsta4 (homo sapiens)"
] | [
"gsta4p (homo sapiens)",
"gstm4-4 (homo sapiens)",
"gsta4-4 (xenopus tropicalis)",
"gsta4-4 (xenopus laevis)"
] | Given the context 'Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.
', answer the user's query. |
What is the biomedical concept corresponding to 'gsta3'? | [
"gsta3 (homo sapiens)",
"gsta3-3 (homo sapiens)",
"glutathione s-transferase alpha 3 (homo sapiens)"
] | [
"gsta3 (gallus gallus)",
"gstm3 (homo sapiens)",
"gst-iii (homo sapiens)",
"gst-3 (homo sapiens)"
] | Given the context 'An incomplete transcript of the previously described GSTA3 gene was identified in a cDNA library derived from 8-9 week placenta.', answer the user's query. |
What is the biomedical concept corresponding to 'gsta3'? | [
"gsta3 (homo sapiens)",
"gsta3-3 (homo sapiens)",
"glutathione s-transferase alpha 3 (homo sapiens)"
] | [
"gsta3 (gallus gallus)",
"gstm3 (homo sapiens)",
"gst-iii (homo sapiens)",
"gst-3 (homo sapiens)"
] | Given the context 'This indicates that the GSTA3 gene is functional and is possibly under specific developmental regulation.', answer the user's query. |
What is the biomedical concept corresponding to 'gsta4'? | [
"gsta4 (homo sapiens)",
"gsta4-4 (homo sapiens)"
] | [
"gst4 (homo sapiens)",
"gsta4p (homo sapiens)",
"gstt4 (homo sapiens)",
"gstm4 (homo sapiens)"
] | Given the context 'A second cDNA, termed GSTA4, was identified in a brain cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'gsta4-4'? | [
"gsta4-4 (homo sapiens)",
"gsta4 (homo sapiens)"
] | [
"gsta4p (homo sapiens)",
"gstm4-4 (homo sapiens)",
"gsta4-4 (xenopus tropicalis)",
"gsta4-4 (xenopus laevis)"
] | Given the context 'The encoded GSTA4-4 enzyme was expressed in Escherichia coli and was found to be immunologically distinct from GSTA1-1 and to have high activity with alk-2-enals.', answer the user's query. |
What is the biomedical concept corresponding to 'gsta1-1'? | [
"gsta1 (homo sapiens)",
"glutathione s-transferase alpha 1 (homo sapiens)"
] | [
"gst1-1 (homo sapiens)",
"gstm1a-1a (homo sapiens)",
"gsta1-1 (sus scrofa)",
"gsta1-1 (xenopus laevis) (glutathione s-transferase alpha 1 s homeolog (xenopus laevis))"
] | Given the context 'The encoded GSTA4-4 enzyme was expressed in Escherichia coli and was found to be immunologically distinct from GSTA1-1 and to have high activity with alk-2-enals.', answer the user's query. |
What is the biomedical concept corresponding to 'gsta4-4'? | [
"gsta4-4 (homo sapiens)",
"gsta4 (homo sapiens)"
] | [
"gsta4p (homo sapiens)",
"gstm4-4 (homo sapiens)",
"gsta4-4 (xenopus tropicalis)",
"gsta4-4 (xenopus laevis)"
] | Given the context 'Although GSTA4-4 appears to be functionally similar to the mouse GST5.7 and rat GST8-8 Alpha class enzymes, sequence comparisons and phylogenetic analysis suggest that GSTA4-4 may be a member of a distinct Alpha class subgroup.', answer the user's query. |
What is the biomedical concept corresponding to 'gst5.7'? | [
"gst5.7 (mus musculus)"
] | [
"gst-5 (homo sapiens)",
"gst5 (homo sapiens)",
"gsta5 (homo sapiens)",
"gstm5-5 (homo sapiens)"
] | Given the context 'Although GSTA4-4 appears to be functionally similar to the mouse GST5.7 and rat GST8-8 Alpha class enzymes, sequence comparisons and phylogenetic analysis suggest that GSTA4-4 may be a member of a distinct Alpha class subgroup.', answer the user's query. |
What is the biomedical concept corresponding to 'gsta4-4'? | [
"gsta4-4 (homo sapiens)",
"gsta4 (homo sapiens)"
] | [
"gsta4p (homo sapiens)",
"gstm4-4 (homo sapiens)",
"gsta4-4 (xenopus tropicalis)",
"gsta4-4 (xenopus laevis)"
] | Given the context 'Although GSTA4-4 appears to be functionally similar to the mouse GST5.7 and rat GST8-8 Alpha class enzymes, sequence comparisons and phylogenetic analysis suggest that GSTA4-4 may be a member of a distinct Alpha class subgroup.', answer the user's query. |
What is the biomedical concept corresponding to 'actinin-4'? | [
"actinin-4 (homo sapiens)",
"actinin alpha 4 (homo sapiens)",
"actn4 (homo sapiens)"
] | [
"actin;actin-4 (caenorhabditis elegans)",
"actn4 (mus musculus)",
"actinin alpha 4 (mus musculus)",
"actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis))"
] | Given the context 'Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion.
', answer the user's query. |
What is the biomedical concept corresponding to 'actinin-4'? | [
"actinin-4 (homo sapiens)",
"actinin alpha 4 (homo sapiens)",
"actn4 (homo sapiens)"
] | [
"actin;actin-4 (caenorhabditis elegans)",
"actn4 (mus musculus)",
"actinin alpha 4 (mus musculus)",
"actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis))"
] | Given the context 'This isoform (designated actinin-4) was concentrated in the cytoplasm where cells were sharply extended and in cells migrating and located at the edge of cell clusters, but was absent from focal adhesion plaques or adherens junctions, where the classic isoform (actinin-1) was concentrated.', answer the user's query. |
What is the biomedical concept corresponding to 'actinin-1'? | [
"actinin alpha 1 (homo sapiens)",
"actn1 (homo sapiens)"
] | [
"actinin-4 (homo sapiens)",
"alpha-actinin, sarcomeric (caenorhabditis elegans)",
"actinin (xenopus laevis) (actinin alpha 1 s homeolog (xenopus laevis))",
"actinin (xenopus laevis) (actinin alpha 1 l homeolog (xenopus laevis))"
] | Given the context 'This isoform (designated actinin-4) was concentrated in the cytoplasm where cells were sharply extended and in cells migrating and located at the edge of cell clusters, but was absent from focal adhesion plaques or adherens junctions, where the classic isoform (actinin-1) was concentrated.', answer the user's query. |
What is the biomedical concept corresponding to 'actinin-4'? | [
"actinin-4 (homo sapiens)",
"actinin alpha 4 (homo sapiens)",
"actn4 (homo sapiens)"
] | [
"actin;actin-4 (caenorhabditis elegans)",
"actn4 (mus musculus)",
"actinin alpha 4 (mus musculus)",
"actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis))"
] | Given the context 'Actinin-4 shifted steadily from the cytoplasm to the nucleus upon inhibition of phosphatidylinositol 3 kinase or actin depolymerization.', answer the user's query. |
What is the biomedical concept corresponding to 'actinin-4'? | [
"actinin-4 (homo sapiens)",
"actinin alpha 4 (homo sapiens)",
"actn4 (homo sapiens)"
] | [
"actin;actin-4 (caenorhabditis elegans)",
"actn4 (mus musculus)",
"actinin alpha 4 (mus musculus)",
"actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis))"
] | Given the context 'The cytoplasmic localization of actinin-4 was closely associated with an infiltrative histological phenotype and correlated significantly with a poorer prognosis in 61 cases of breast cancer.', answer the user's query. |
What is the biomedical concept corresponding to 'actinin-4'? | [
"actinin-4 (homo sapiens)",
"actinin alpha 4 (homo sapiens)",
"actn4 (homo sapiens)"
] | [
"actin;actin-4 (caenorhabditis elegans)",
"actn4 (mus musculus)",
"actinin alpha 4 (mus musculus)",
"actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis))"
] | Given the context 'These findings suggest that cytoplasmic actinin-4 regulates the actin cytoskeleton and increases cellular motility and that its inactivation by transfer to the nucleus abolishes the metastatic potential of human cancers.', answer the user's query. |
What is the biomedical concept corresponding to 'hla-g class i'? | [
"major histocompatibility complex, class i, g (homo sapiens)",
"hla-g (homo sapiens)",
"mhc-g (homo sapiens)"
] | [
"major histocompatibility complex, class i, c (homo sapiens)",
"major histocompatibility complex, class i, e (homo sapiens)",
"major histocompatibility complex, class i, a (homo sapiens)",
"major histocompatibility complex, class i, f (homo sapiens)"
] | Given the context 'Considering the well established role of nonclassical HLA-G class I molecules in inhibiting natural killer (NK) cell function, the consequence of abnormal HLA-G expression in malignant cells should be the escape of tumors from immunosurveillance.', answer the user's query. |
What is the biomedical concept corresponding to 'hla-g1'? | [
"major histocompatibility complex, class i, g (homo sapiens)",
"hla-g (homo sapiens)"
] | [
"hla-z1 (homo sapiens)",
"hla-hb1 (homo sapiens)",
"major histocompatibility complex, class i, e (homo sapiens)",
"hla-h (homo sapiens) (major histocompatibility complex, class i, h (pseudogene) (homo sapiens))"
] | Given the context 'Our analysis of three melanoma cell lines and ex vivo biopsy demonstrated that (i) IGR and M74 human melanoma cell lines exhibit a high level of HLA-G transcription with differential HLA-G isoform transcription and protein expression patterns, (ii) a higher level of HLA-G transcription ex vivo is detected in a skin melanoma metastasis biopsy compared with a healthy skin fragment from the same individual, and (iii) HLA-G protein isoforms other than membrane-bound HLA-G1 protect IGR from NK lysis.', answer the user's query. |
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