query stringlengths 53 129 | positive listlengths 1 8 | negative listlengths 10 10 | system stringlengths 70 592 |
|---|---|---|---|
What is the biomedical concept corresponding to 'he2'? | [
"he2c (homo sapiens)"
] | [
"he1 (homo sapiens)",
"he4 (homo sapiens)",
"he6 (homo sapiens)",
"he5 (homo sapiens)",
"he3b (homo sapiens)",
"he3a (homo sapiens)",
"heg1 (homo sapiens)",
"he3-alpha (homo sapiens)",
"he3-beta (homo sapiens)",
"he9 (homo sapiens)"
] | Given the context 'Immunohistochemistry and immunofluorescence showed that the predicted HE2 peptide is present in the epididymal epithelium and on the sperm surface, where it adopts a typical antigenic pattern with a subacrosomal equatorial distribution on the sperm head.', answer the user's query. |
What is the biomedical concept corresponding to 'nicotinamide n-methyltransferase'? | [
"nicotinamide n-methyltransferase (homo sapiens)",
"nnmt (homo sapiens)"
] | [
"nicotinamide n-methyltransferase (mus musculus)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nicotinamide n-methyltransferase (rattus norvegicus)",
"nicotinamide n-methyltransferase-like (bos taurus)",
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransfer... | Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', answer the user's query. |
What is the biomedical concept corresponding to 'nicotinamide n-methyltransferase'? | [
"nicotinamide n-methyltransferase (homo sapiens)",
"nnmt (homo sapiens)"
] | [
"nicotinamide n-methyltransferase (mus musculus)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nicotinamide n-methyltransferase (rattus norvegicus)",
"nicotinamide n-methyltransferase-like (bos taurus)",
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransfer... | Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'Human liver NNMT activity has a bimodal frequency distribution, an observation which raises the possibility that this enzyme activity might be regulated by a genetic polymorphism, a polymorphism that could have functional implications for individual differences in drug and xenobiotic toxicity.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'As a first step toward testing that hypothesis, we set out to clone and express a cDNA for human liver NNMT.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'Human liver NNMT was partially purified, photoaffinity-labeled, subjected to limited proteolysis, and partial amino acid sequence information was obtained.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'The polymerase chain reaction was then used to amplify a 550-nucleotide sequence with human liver cDNA as template and primers designed on the basis of the NNMT amino acid sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'The 5'- and 3'-ends of a human liver NNMT cDNA were obtained by use of the rapid amplification of cDNA ends.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'The combined use of these approaches resulted in the isolation of a human liver NNMT cDNA that was 969 nucleotides in length, with a 792-nucleotide open reading frame that encoded a 264-amino acid protein with a calculated molecular mass of 29.6 kDa.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'The human liver NNMT cDNA was transcribed in vitro and translated with a reticulocyte lysate system to yield a protein with a molecular mass of approximately 29 kDa that comigrated during SDS-polyacrylamide gel electrophoresis with photoaffinity-labeled human liver NNMT.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'The human liver NNMT cDNA was transcribed in vitro and translated with a reticulocyte lysate system to yield a protein with a molecular mass of approximately 29 kDa that comigrated during SDS-polyacrylamide gel electrophoresis with photoaffinity-labeled human liver NNMT.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'The NNMT cDNA was also subcloned into the eukaryotic expression vector p91023(B).', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'COS-1 cells transfected with this construct expressed a high level of NNMT enzymatic activity, and the biochemical properties of this activity were similar to those of human liver NNMT.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'COS-1 cells transfected with this construct expressed a high level of NNMT enzymatic activity, and the biochemical properties of this activity were similar to those of human liver NNMT.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'Human liver NNMT and transfected COS-1 cell NNMT had apparent Km values for the two cosubstrates for the reaction, nicotinamide and S-adenosyl-L-methionine, of 0.43 and 0.38 mM and of 1.8 and 2.2 microM, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'Human liver NNMT and transfected COS-1 cell NNMT had apparent Km values for the two cosubstrates for the reaction, nicotinamide and S-adenosyl-L-methionine, of 0.43 and 0.38 mM and of 1.8 and 2.2 microM, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'IC50 values for the inhibition of NNMT by N1-methylnicotinamide were 60 and 30 microns for human liver and COS-1 cell-expressed NNMT, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'IC50 values for the inhibition of NNMT by N1-methylnicotinamide were 60 and 30 microns for human liver and COS-1 cell-expressed NNMT, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'Cloning of a cDNA for human liver NNMT will help make it possible to test the hypothesis that inheritance may play a role in the regulation of individual differences in human liver NNMT activity.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nnms (homo sapiens)",
"nnt (homo sapiens)",
"nicotinamide n-methyltransferase-like (caenorhabditis elegans)",
"nnmt (mus musculus)",
"n-terminal methyltransferase (drosophila melanogaster)",
"nn... | Given the context 'Cloning of a cDNA for human liver NNMT will help make it possible to test the hypothesis that inheritance may play a role in the regulation of individual differences in human liver NNMT activity.', answer the user's query. |
What is the biomedical concept corresponding to 'capl'? | [
"capl (homo sapiens)"
] | [
"capg (homo sapiens) (capping actin protein, gelsolin like (homo sapiens))",
"capn1 (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn1.l (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn4 (xenopus laevis) (calpain, small subunit 1 l hom... | Given the context 'Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY.
', answer the user's query. |
What is the biomedical concept corresponding to 'cacy'? | [
"cacy (homo sapiens)"
] | [
"cact (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cac (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cacy (mus musculus)",
"cactus (drosophila melanogaster) (cacophony (drosophila melanogaster))",
"caca (homo sapiens)",
"cact (drosophila melanogaster) (cacophony (droso... | Given the context 'Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY.
', answer the user's query. |
What is the biomedical concept corresponding to 'capl'? | [
"capl (homo sapiens)"
] | [
"capg (homo sapiens) (capping actin protein, gelsolin like (homo sapiens))",
"capn1 (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn1.l (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn4 (xenopus laevis) (calpain, small subunit 1 l hom... | Given the context 'The S100 proteins CAPL and CACY are expressed in a tissue- and cell-specific manner and have been reported to be associated with the metastatic phenotype of tumor cells.', answer the user's query. |
What is the biomedical concept corresponding to 'cacy'? | [
"cacy (homo sapiens)"
] | [
"cact (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cac (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cacy (mus musculus)",
"cactus (drosophila melanogaster) (cacophony (drosophila melanogaster))",
"caca (homo sapiens)",
"cact (drosophila melanogaster) (cacophony (droso... | Given the context 'The S100 proteins CAPL and CACY are expressed in a tissue- and cell-specific manner and have been reported to be associated with the metastatic phenotype of tumor cells.', answer the user's query. |
What is the biomedical concept corresponding to 'capl'? | [
"capl (homo sapiens)"
] | [
"capg (homo sapiens) (capping actin protein, gelsolin like (homo sapiens))",
"capn1 (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn1.l (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn4 (xenopus laevis) (calpain, small subunit 1 l hom... | Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', answer the user's query. |
What is the biomedical concept corresponding to 'cacy'? | [
"cacy (homo sapiens)"
] | [
"cact (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cac (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cacy (mus musculus)",
"cactus (drosophila melanogaster) (cacophony (drosophila melanogaster))",
"caca (homo sapiens)",
"cact (drosophila melanogaster) (cacophony (droso... | Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', answer the user's query. |
What is the biomedical concept corresponding to 'cacy'? | [
"cacy (homo sapiens)"
] | [
"cact (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cac (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cacy (mus musculus)",
"cactus (drosophila melanogaster) (cacophony (drosophila melanogaster))",
"caca (homo sapiens)",
"cact (drosophila melanogaster) (cacophony (droso... | Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', answer the user's query. |
What is the biomedical concept corresponding to 'capl'? | [
"capl (homo sapiens)"
] | [
"capg (homo sapiens) (capping actin protein, gelsolin like (homo sapiens))",
"capn1 (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn1.l (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn4 (xenopus laevis) (calpain, small subunit 1 l hom... | Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', answer the user's query. |
What is the biomedical concept corresponding to 'cacy'? | [
"cacy (homo sapiens)"
] | [
"cact (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cac (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cacy (mus musculus)",
"cactus (drosophila melanogaster) (cacophony (drosophila melanogaster))",
"caca (homo sapiens)",
"cact (drosophila melanogaster) (cacophony (droso... | Given the context 'Conformational changes in the Tyr microenvironment of CACY indicate that Ca2+ binding induces a shift of Tyr to a less polar environment.', answer the user's query. |
What is the biomedical concept corresponding to 'capl'? | [
"capl (homo sapiens)"
] | [
"capg (homo sapiens) (capping actin protein, gelsolin like (homo sapiens))",
"capn1 (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn1.l (xenopus laevis) (calpain 1, (mu/i) large subunit l homeolog (xenopus laevis))",
"capn4 (xenopus laevis) (calpain, small subunit 1 l hom... | Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'cacy'? | [
"cacy (homo sapiens)"
] | [
"cact (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cac (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cacy (mus musculus)",
"cactus (drosophila melanogaster) (cacophony (drosophila melanogaster))",
"caca (homo sapiens)",
"cact (drosophila melanogaster) (cacophony (droso... | Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'cacy'? | [
"cacy (homo sapiens)"
] | [
"cact (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cac (drosophila melanogaster) (cactus (drosophila melanogaster))",
"cacy (mus musculus)",
"cactus (drosophila melanogaster) (cacophony (drosophila melanogaster))",
"caca (homo sapiens)",
"cact (drosophila melanogaster) (cacophony (droso... | Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'x-arrestin'? | [
"arrestin 3 (homo sapiens)"
] | [
"arrestin 1 (drosophila melanogaster)",
"arr (drosophila melanogaster) (arrestin 1 (drosophila melanogaster))",
"arrestin (xenopus laevis) (arrestin beta 1 s homeolog (xenopus laevis))",
"beta-arrestin (drosophila melanogaster)",
"arrestin (xenopus laevis) (arrestin beta 1 l homeolog (xenopus laevis))",
"... | Given the context 'X-arrestin: a new retinal arrestin mapping to the X chromosome.
', answer the user's query. |
What is the biomedical concept corresponding to 'x-arrestin'? | [
"arrestin 3 (homo sapiens)"
] | [
"arrestin 1 (drosophila melanogaster)",
"arr (drosophila melanogaster) (arrestin 1 (drosophila melanogaster))",
"arrestin (xenopus laevis) (arrestin beta 1 s homeolog (xenopus laevis))",
"beta-arrestin (drosophila melanogaster)",
"arrestin (xenopus laevis) (arrestin beta 1 l homeolog (xenopus laevis))",
"... | Given the context 'Chromosomal mapping localized this new arrestin gene to the proximal long arm of the X chromosome, hence it was named X-arrestin.', answer the user's query. |
What is the biomedical concept corresponding to '140-kda subunit of rfc'? | [
"rfc40 (homo sapiens) (replication factor c subunit 1 (homo sapiens))",
"rfc1 (homo sapiens) (replication factor c subunit 1 (homo sapiens))",
"replication factor c subunit 1 (homo sapiens)"
] | [
"140kda (mus musculus) (replication factor c (activator 1) 1 (mus musculus))",
"rf-c 140 (drosophila melanogaster)",
"rfc140 (drosophila melanogaster)",
"rfc40 (homo sapiens) (replication factor c subunit 2 (homo sapiens))",
"rfb30 (homo sapiens)",
"rfc2 (homo sapiens)",
"rfc (drosophila melanogaster) (... | Given the context 'Regions of similarity were also seen between the amino acid sequences of the 140-kDa subunit of RFC, poly(ADP-ribose) polymerase, and bacterial DNA ligases--possibly representing a conserved structural feature of these proteins that bind similar DNA substrates.', answer the user's query. |
What is the biomedical concept corresponding to 'efp'? | [
"efp (homo sapiens)"
] | [
"efp1 (homo sapiens)",
"ef1 (drosophila melanogaster)",
"efr (drosophila melanogaster)",
"efl1 (homo sapiens) (elongation factor like gtpase 1 (homo sapiens))",
"efw1 (drosophila melanogaster)",
"ef (drosophila melanogaster) (elfin (drosophila melanogaster))",
"efl1 (mus musculus) (elongation factor lik... | Given the context 'It has a RING finger motif present in a family of apparent DNA-binding proteins and is designated estrogen-responsive finger protein (efp).', answer the user's query. |
What is the biomedical concept corresponding to 'efp'? | [
"efp (homo sapiens)"
] | [
"efp1 (homo sapiens)",
"ef1 (drosophila melanogaster)",
"efr (drosophila melanogaster)",
"efl1 (homo sapiens) (elongation factor like gtpase 1 (homo sapiens))",
"efw1 (drosophila melanogaster)",
"ef (drosophila melanogaster) (elfin (drosophila melanogaster))",
"efl1 (mus musculus) (elongation factor lik... | Given the context 'efp cDNA contains a consensus estrogen-responsive element at the 3' untranslated region that can act as a downstream estrogen-dependent enhancer.', answer the user's query. |
What is the biomedical concept corresponding to 'efp'? | [
"efp (homo sapiens)"
] | [
"efp1 (homo sapiens)",
"ef1 (drosophila melanogaster)",
"efr (drosophila melanogaster)",
"efl1 (homo sapiens) (elongation factor like gtpase 1 (homo sapiens))",
"efw1 (drosophila melanogaster)",
"ef (drosophila melanogaster) (elfin (drosophila melanogaster))",
"efl1 (mus musculus) (elongation factor lik... | Given the context 'Moreover, efp is regulated by estrogen as demonstrated at both the mRNA and the protein level in ER-positive cells derived from mammary gland.', answer the user's query. |
What is the biomedical concept corresponding to 'efp'? | [
"efp (homo sapiens)"
] | [
"efp1 (homo sapiens)",
"ef1 (drosophila melanogaster)",
"efr (drosophila melanogaster)",
"efl1 (homo sapiens) (elongation factor like gtpase 1 (homo sapiens))",
"efw1 (drosophila melanogaster)",
"ef (drosophila melanogaster) (elfin (drosophila melanogaster))",
"efl1 (mus musculus) (elongation factor lik... | Given the context 'These data suggest that efp may represent an estrogen-responsive transcription factor that mediates phenotypic expression of the diverse estrogen action.', answer the user's query. |
What is the biomedical concept corresponding to 'lon protease'? | [
"lon protease (escherichia coli str. k-12 substr. mg1655)"
] | [
"lon protease (drosophila melanogaster)",
"lon (drosophila melanogaster) (lon protease (drosophila melanogaster))",
"lon protease homolog, mitochondrial (caenorhabditis elegans)",
"lonp (homo sapiens) (lon peptidase 1, mitochondrial (homo sapiens))",
"lon peptidase 1, mitochondrial (homo sapiens)",
"lon-2... | Given the context 'A human mitochondrial ATP-dependent protease that is highly homologous to bacterial Lon protease.
', answer the user's query. |
What is the biomedical concept corresponding to 'lon protease'? | [
"lonp (homo sapiens) (lon peptidase 1, mitochondrial (homo sapiens))",
"lon peptidase 1, mitochondrial (homo sapiens)",
"lon (homo sapiens)",
"lonp1 (homo sapiens)"
] | [
"lon protease (drosophila melanogaster)",
"lon (drosophila melanogaster) (lon protease (drosophila melanogaster))",
"lon protease homolog, mitochondrial (caenorhabditis elegans)",
"lon protease (escherichia coli str. k-12 substr. mg1655)",
"lon-2 (caenorhabditis elegans)",
"lonp (homo sapiens) (lon peptid... | Given the context 'A single species of mRNA was found for this Lon protease in all human tissues examined.', answer the user's query. |
What is the biomedical concept corresponding to 'lon protease'? | [
"lonp (homo sapiens) (lon peptidase 1, mitochondrial (homo sapiens))",
"lon peptidase 1, mitochondrial (homo sapiens)",
"lon (homo sapiens)",
"lonp1 (homo sapiens)"
] | [
"lon protease (drosophila melanogaster)",
"lon (drosophila melanogaster) (lon protease (drosophila melanogaster))",
"lon protease homolog, mitochondrial (caenorhabditis elegans)",
"lon protease (escherichia coli str. k-12 substr. mg1655)",
"lon-2 (caenorhabditis elegans)",
"lonp (homo sapiens) (lon peptid... | Given the context 'Immunofluorescence microscopy suggested a predominantly mitochondrial localization for the Lon protease in cultured human cells.', answer the user's query. |
What is the biomedical concept corresponding to 'lon protease'? | [
"lon protease (escherichia coli str. k-12 substr. mg1655)"
] | [
"lon protease (drosophila melanogaster)",
"lon (drosophila melanogaster) (lon protease (drosophila melanogaster))",
"lon protease homolog, mitochondrial (caenorhabditis elegans)",
"lonp (homo sapiens) (lon peptidase 1, mitochondrial (homo sapiens))",
"lon peptidase 1, mitochondrial (homo sapiens)",
"lon-2... | Given the context 'A truncated LON gene, in which translation was initiated at Met118 of the coding sequence, was expressed in Escherichia coli and produced a protease that degraded alpha-casein in vitro in an ATP-dependent manner and had other properties similar to E. coli Lon protease.', answer the user's query. |
What is the biomedical concept corresponding to 'nac'? | [
"nacp (homo sapiens)"
] | [
"naca (homo sapiens)",
"beta-naca (homo sapiens)",
"nac (drosophila melanogaster) (neuronally altered carbohydrate (drosophila melanogaster))",
"nac-2 (homo sapiens)",
"nac-1 (homo sapiens)",
"nacb (homo sapiens)",
"nac-alpha (drosophila melanogaster)",
"alpha-nac (drosophila melanogaster)",
"nac (d... | Given the context 'We tentatively named this 35-amino acid peptide NAC (non-A beta component of AD amyloid) and its precursor NACP.', answer the user's query. |
What is the biomedical concept corresponding to 'non-a beta component of ad amyloid'? | [
"synuclein alpha (homo sapiens)"
] | [
"abeta (homo sapiens)",
"aaa (homo sapiens) (amyloid beta precursor protein (homo sapiens))",
"amyloid beta precursor protein (homo sapiens)",
"pn-ii (homo sapiens) (amyloid beta precursor protein (homo sapiens))",
"abeta (mus musculus) (amyloid beta precursor protein (mus musculus))",
"synuclein, beta (r... | Given the context 'We tentatively named this 35-amino acid peptide NAC (non-A beta component of AD amyloid) and its precursor NACP.', answer the user's query. |
What is the biomedical concept corresponding to 'nacp'? | [
"nacp (homo sapiens)"
] | [
"nac-alpha (drosophila melanogaster)",
"nac (drosophila melanogaster) (nascent polypeptide associated complex protein alpha subunit (drosophila melanogaster))",
"naca (oryctolagus cuniculus) (nascent polypeptide associated complex subunit alpha (oryctolagus cuniculus))",
"nacap1 (homo sapiens)",
"nac-1 (hom... | Given the context 'We tentatively named this 35-amino acid peptide NAC (non-A beta component of AD amyloid) and its precursor NACP.', answer the user's query. |
What is the biomedical concept corresponding to 'nac'? | [
"nacp (homo sapiens)"
] | [
"naca (homo sapiens)",
"beta-naca (homo sapiens)",
"nac (drosophila melanogaster) (neuronally altered carbohydrate (drosophila melanogaster))",
"nac-2 (homo sapiens)",
"nac-1 (homo sapiens)",
"nacb (homo sapiens)",
"nac-alpha (drosophila melanogaster)",
"alpha-nac (drosophila melanogaster)",
"nac (d... | Given the context 'NAC is the second component, after A beta, identified chemically in the purified AD amyloid preparation.', answer the user's query. |
What is the biomedical concept corresponding to 'nac'? | [
"nacp (homo sapiens)"
] | [
"naca (homo sapiens)",
"beta-naca (homo sapiens)",
"nac (drosophila melanogaster) (neuronally altered carbohydrate (drosophila melanogaster))",
"nac-2 (homo sapiens)",
"nac-1 (homo sapiens)",
"nacb (homo sapiens)",
"nac-alpha (drosophila melanogaster)",
"alpha-nac (drosophila melanogaster)",
"nac (d... | Given the context 'Secondary structure predictions indicate that the NAC peptide sequence has a strong tendency to form beta-structures consistent with its association with amyloid.', answer the user's query. |
What is the biomedical concept corresponding to 'nacp'? | [
"nacp (homo sapiens)"
] | [
"nac-alpha (drosophila melanogaster)",
"nac (drosophila melanogaster) (nascent polypeptide associated complex protein alpha subunit (drosophila melanogaster))",
"naca (oryctolagus cuniculus) (nascent polypeptide associated complex subunit alpha (oryctolagus cuniculus))",
"nacap1 (homo sapiens)",
"nac-1 (hom... | Given the context 'NACP is detected as a M(r) 19,000 protein in the cytosolic fraction of brain homogenates and comigrates on immunoblots with NACP synthesized in Escherichia coli from NACP cDNA.', answer the user's query. |
What is the biomedical concept corresponding to 'nacp'? | [
"nacp (homo sapiens)"
] | [
"nac-alpha (drosophila melanogaster)",
"nac (drosophila melanogaster) (nascent polypeptide associated complex protein alpha subunit (drosophila melanogaster))",
"naca (oryctolagus cuniculus) (nascent polypeptide associated complex subunit alpha (oryctolagus cuniculus))",
"nacap1 (homo sapiens)",
"nac-1 (hom... | Given the context 'NACP is detected as a M(r) 19,000 protein in the cytosolic fraction of brain homogenates and comigrates on immunoblots with NACP synthesized in Escherichia coli from NACP cDNA.', answer the user's query. |
What is the biomedical concept corresponding to 'nacp'? | [
"nacp (homo sapiens)"
] | [
"nac-alpha (drosophila melanogaster)",
"nac (drosophila melanogaster) (nascent polypeptide associated complex protein alpha subunit (drosophila melanogaster))",
"naca (oryctolagus cuniculus) (nascent polypeptide associated complex subunit alpha (oryctolagus cuniculus))",
"nacap1 (homo sapiens)",
"nac-1 (hom... | Given the context 'NACP is detected as a M(r) 19,000 protein in the cytosolic fraction of brain homogenates and comigrates on immunoblots with NACP synthesized in Escherichia coli from NACP cDNA.', answer the user's query. |
What is the biomedical concept corresponding to 'nacp'? | [
"nacp (homo sapiens)"
] | [
"nac-alpha (drosophila melanogaster)",
"nac (drosophila melanogaster) (nascent polypeptide associated complex protein alpha subunit (drosophila melanogaster))",
"naca (oryctolagus cuniculus) (nascent polypeptide associated complex subunit alpha (oryctolagus cuniculus))",
"nacap1 (homo sapiens)",
"nac-1 (hom... | Given the context 'NACP mRNA is expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver, suggesting its ubiquitous and brain-specific functions.', answer the user's query. |
What is the biomedical concept corresponding to 'nacp'? | [
"nacp (homo sapiens)"
] | [
"nac-alpha (drosophila melanogaster)",
"nac (drosophila melanogaster) (nascent polypeptide associated complex protein alpha subunit (drosophila melanogaster))",
"naca (oryctolagus cuniculus) (nascent polypeptide associated complex subunit alpha (oryctolagus cuniculus))",
"nacap1 (homo sapiens)",
"nac-1 (hom... | Given the context 'The availability of the cDNA encoding full-length NACP should help to elucidate the mechanisms of amyloidosis in AD.', answer the user's query. |
What is the biomedical concept corresponding to 'nrf1'? | [
"nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))",
"nrf-1 (homo sapiens)"
] | [
"nrf-1 (drosophila melanogaster)",
"nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))",
"nrf1 (mus musculus) (nuclear respiratory factor 1 (mus musculus))",
"nrf1 (mus musculus) (nuclear factor, erythroid derived 2,-like 1 (mus musculus))",
"nrf (homo sapiens)",
"nrf-2 (homo sapiens)",
"... | Given the context 'Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast.
', answer the user's query. |
What is the biomedical concept corresponding to 'nrf1'? | [
"nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))",
"nrf-1 (homo sapiens)"
] | [
"nrf-1 (drosophila melanogaster)",
"nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))",
"nrf1 (mus musculus) (nuclear respiratory factor 1 (mus musculus))",
"nrf1 (mus musculus) (nuclear factor, erythroid derived 2,-like 1 (mus musculus))",
"nrf (homo sapiens)",
"nrf-2 (homo sapiens)",
"... | Given the context 'We have devised a complementation assay in yeast to clone mammalian transcriptional activators and have used it to identify a human basic leucine-zipper transcription factor that we have designated Nrf1 for NF-E2-related factor 1.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-e2-related factor 1'? | [
"nfe2l1 (homo sapiens)",
"nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))",
"nfe2 like bzip transcription factor 1 (homo sapiens)"
] | [
"nf-e2 (homo sapiens)",
"nfe2 (homo sapiens)",
"nf-e2 (xenopus laevis) (nfe2 like bzip transcription factor 2 s homeolog (xenopus laevis))",
"nuclear factor, erythroid derived 2,-like 1 (mus musculus)",
"nf-e2 (xenopus tropicalis) (nuclear factor, erythroid 2 (xenopus tropicalis))",
"nuclear factor, eryth... | Given the context 'We have devised a complementation assay in yeast to clone mammalian transcriptional activators and have used it to identify a human basic leucine-zipper transcription factor that we have designated Nrf1 for NF-E2-related factor 1.', answer the user's query. |
What is the biomedical concept corresponding to 'nrf1'? | [
"nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))",
"nrf-1 (homo sapiens)"
] | [
"nrf-1 (drosophila melanogaster)",
"nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))",
"nrf1 (mus musculus) (nuclear respiratory factor 1 (mus musculus))",
"nrf1 (mus musculus) (nuclear factor, erythroid derived 2,-like 1 (mus musculus))",
"nrf (homo sapiens)",
"nrf-2 (homo sapiens)",
"... | Given the context 'Nrf1 potentially encodes a 742-aa protein and displays marked homology to the mouse and human NF-E2 transcription factors.', answer the user's query. |
What is the biomedical concept corresponding to 'nrf1'? | [
"nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))",
"nrf-1 (homo sapiens)"
] | [
"nrf-1 (drosophila melanogaster)",
"nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))",
"nrf1 (mus musculus) (nuclear respiratory factor 1 (mus musculus))",
"nrf1 (mus musculus) (nuclear factor, erythroid derived 2,-like 1 (mus musculus))",
"nrf (homo sapiens)",
"nrf-2 (homo sapiens)",
"... | Given the context 'Nrf1 activates transcription via NF-E2 binding sites in yeast cells.', answer the user's query. |
What is the biomedical concept corresponding to 'nrf1'? | [
"nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))",
"nrf-1 (homo sapiens)"
] | [
"nrf-1 (drosophila melanogaster)",
"nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))",
"nrf1 (mus musculus) (nuclear respiratory factor 1 (mus musculus))",
"nrf1 (mus musculus) (nuclear factor, erythroid derived 2,-like 1 (mus musculus))",
"nrf (homo sapiens)",
"nrf-2 (homo sapiens)",
"... | Given the context 'The ubiquitous expression pattern of Nrf1 and the range of promoters containing the NF-E2 binding motif suggest that this gene may play a role in the regulation of heme synthesis and ferritin genes.', answer the user's query. |
What is the biomedical concept corresponding to 'beta-subunit of rod phosphodiesterase'? | [
"pdeb (homo sapiens)",
"pde6b (homo sapiens)",
"phosphodiesterase 6b (homo sapiens)"
] | [
"phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide (mus musculus)",
"rd (mus musculus) (phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide (mus musculus))",
"rod cgmp-specific 3',5'-cyclic phosphodiesterase subunit beta-like (xenopus laevis)",
"phosphodiesterase 1b (homo sapiens)",
"pde1b (... | Given the context 'Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa.
', answer the user's query. |
What is the biomedical concept corresponding to 'beta-subunit of rod cgmp phosphodiesterase'? | [
"gmp-pdebeta (homo sapiens)",
"pdeb (homo sapiens)",
"pde6b (homo sapiens)"
] | [
"rod cgmp-specific 3',5'-cyclic phosphodiesterase subunit beta-like (xenopus laevis)",
"phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide (mus musculus)",
"rd (mus musculus) (phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide (mus musculus))",
"pde1b (homo sapiens)",
"phosphodiesterase 6b, ... | Given the context 'We have found four mutations in the human gene encoding the beta-subunit of rod cGMP phosphodiesterase (PDE beta) that cosegregate with autosomal recessive retinitis pigmentosa, a degenerative disease of photoreceptors.', answer the user's query. |
What is the biomedical concept corresponding to 'pde beta'? | [
"pdeb (homo sapiens)",
"pde6b (homo sapiens)"
] | [
"pde1b (homo sapiens)",
"pde3b (homo sapiens)",
"pde1b (mus musculus)",
"phosphodiesterase 1b (homo sapiens)",
"pde7b (homo sapiens)",
"pdeii (drosophila melanogaster)",
"pde8b (homo sapiens)",
"pde1b.l (xenopus laevis) (phosphodiesterase 1b l homeolog (xenopus laevis))",
"pde4b (homo sapiens)",
"... | Given the context 'We have found four mutations in the human gene encoding the beta-subunit of rod cGMP phosphodiesterase (PDE beta) that cosegregate with autosomal recessive retinitis pigmentosa, a degenerative disease of photoreceptors.', answer the user's query. |
What is the biomedical concept corresponding to 'pde beta'? | [
"pdeb (homo sapiens)",
"pde6b (homo sapiens)"
] | [
"pde1b (homo sapiens)",
"pde3b (homo sapiens)",
"pde1b (mus musculus)",
"phosphodiesterase 1b (homo sapiens)",
"pde7b (homo sapiens)",
"pdeii (drosophila melanogaster)",
"pde8b (homo sapiens)",
"pde1b.l (xenopus laevis) (phosphodiesterase 1b l homeolog (xenopus laevis))",
"pde4b (homo sapiens)",
"... | Given the context 'PDE beta is the second member of the phototransduction cascade besides rhodopsin that is absent or altered as a cause of retinitis pigmentosa, suggesting that other members of this pathway may be defective in other forms of this disease.', answer the user's query. |
What is the biomedical concept corresponding to 'rhodopsin'? | [
"rhodopsin (homo sapiens)",
"rho (homo sapiens) (rhodopsin (homo sapiens))"
] | [
"rhodopsin (drosophila melanogaster)",
"rhodopsin-1 (drosophila melanogaster)",
"retinal pigment epithelium-derived rhodopsin homolog (homo sapiens)",
"retinal pigment epithelium-derived rhodopsin homolog (xenopus tropicalis)",
"rh (drosophila melanogaster) (rhodopsin 3 (drosophila melanogaster))",
"rho (... | Given the context 'PDE beta is the second member of the phototransduction cascade besides rhodopsin that is absent or altered as a cause of retinitis pigmentosa, suggesting that other members of this pathway may be defective in other forms of this disease.', answer the user's query. |
What is the biomedical concept corresponding to 'c-rel'? | [
"c-rel (homo sapiens)",
"rel proto-oncogene, nf-kb subunit (homo sapiens)"
] | [
"c-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog s homeolog (xenopus laevis))",
"c-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog l homeolog (xenopus laevis))",
"v-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog s ho... | Given the context 'Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization.
', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappa bp50'? | [
"nfkb-p50 (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nfkb-p105 (homo sapiens)"
] | [
"nfkb-p50 (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 s homeolog (xenopus laevis))",
"nfkb-p50 (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog (xenopus laevis))",
"p50 (mus musculus) (nuclear factor of kappa light polyp... | Given the context 'Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization.
', answer the user's query. |
What is the biomedical concept corresponding to 'lyt-10'? | [
"lyt-10 (homo sapiens)",
"lyt10 (homo sapiens)"
] | [
"ly-10 (mus musculus)",
"ly9 (homo sapiens)",
"ly108 (homo sapiens)",
"nkat-10 (homo sapiens)",
"ly110 (homo sapiens)",
"ly-3 (homo sapiens)",
"lyt-10 (xenopus tropicalis)",
"lyl1 (homo sapiens)",
"ly-2 (drosophila melanogaster)",
"lyf-1 (homo sapiens)"
] | Given the context 'Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization.
', answer the user's query. |
What is the biomedical concept corresponding to 'c-rel'? | [
"c-rel (homo sapiens)",
"rel proto-oncogene, nf-kb subunit (homo sapiens)"
] | [
"c-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog s homeolog (xenopus laevis))",
"c-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog l homeolog (xenopus laevis))",
"v-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog s ho... | Given the context 'We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the transcription factors c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappa bp50'? | [
"nfkb-p50 (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nfkb-p105 (homo sapiens)"
] | [
"nfkb-p50 (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 s homeolog (xenopus laevis))",
"nfkb-p50 (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog (xenopus laevis))",
"p50 (mus musculus) (nuclear factor of kappa light polyp... | Given the context 'We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the transcription factors c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10.', answer the user's query. |
What is the biomedical concept corresponding to 'lyt-10'? | [
"lyt-10 (homo sapiens)",
"lyt10 (homo sapiens)"
] | [
"ly-10 (mus musculus)",
"ly9 (homo sapiens)",
"ly108 (homo sapiens)",
"nkat-10 (homo sapiens)",
"ly110 (homo sapiens)",
"ly-3 (homo sapiens)",
"lyt-10 (xenopus tropicalis)",
"lyl1 (homo sapiens)",
"ly-2 (drosophila melanogaster)",
"lyf-1 (homo sapiens)"
] | Given the context 'We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the transcription factors c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10.', answer the user's query. |
What is the biomedical concept corresponding to 'c-rel'? | [
"c-rel (homo sapiens)",
"rel proto-oncogene, nf-kb subunit (homo sapiens)"
] | [
"c-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog s homeolog (xenopus laevis))",
"c-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog l homeolog (xenopus laevis))",
"v-rel (xenopus laevis) (v-rel avian reticuloendotheliosis viral oncogene homolog s ho... | Given the context 'The previously published assignments of c-rel and NF-kappa Bp50 have been refined to specific bands.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappa bp50'? | [
"nfkb-p50 (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nfkb-p105 (homo sapiens)"
] | [
"nfkb-p50 (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 s homeolog (xenopus laevis))",
"nfkb-p50 (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog (xenopus laevis))",
"p50 (mus musculus) (nuclear factor of kappa light polyp... | Given the context 'The previously published assignments of c-rel and NF-kappa Bp50 have been refined to specific bands.', answer the user's query. |
What is the biomedical concept corresponding to 'lyt-10'? | [
"lyt-10 (homo sapiens)",
"lyt10 (homo sapiens)"
] | [
"ly-10 (mus musculus)",
"ly9 (homo sapiens)",
"ly108 (homo sapiens)",
"nkat-10 (homo sapiens)",
"ly110 (homo sapiens)",
"ly-3 (homo sapiens)",
"lyt-10 (xenopus tropicalis)",
"lyl1 (homo sapiens)",
"ly-2 (drosophila melanogaster)",
"lyf-1 (homo sapiens)"
] | Given the context 'The map position of lyt-10, inferred from its isolation from a t(10;14)(q24;q32) translocation, has been confirmed.', answer the user's query. |
What is the biomedical concept corresponding to 'valyl-trna synthetase'? | [
"valyl-trna synthetase 1 (homo sapiens)",
"vars2 (homo sapiens) (valyl-trna synthetase 1 (homo sapiens))"
] | [
"valyl-trna synthetase (drosophila melanogaster)",
"vrs (drosophila melanogaster) (valyl-trna synthetase (drosophila melanogaster))",
"valyl-trna synthetase, mitochondrial (drosophila melanogaster)",
"valyl-trna synthetase 1 (mus musculus)",
"valyl-trna synthetase 1 (xenopus tropicalis)",
"valyl-trna synt... | Given the context 'Cloning, sequencing and expression of a cDNA encoding mammalian valyl-tRNA synthetase.
', answer the user's query. |
What is the biomedical concept corresponding to 'valyl-trna synthetase'? | [
"valyl-trna synthetase 1 (rattus norvegicus)"
] | [
"valyl-trna synthetase (drosophila melanogaster)",
"valyl-trna synthetase 1 (homo sapiens)",
"vrs (drosophila melanogaster) (valyl-trna synthetase (drosophila melanogaster))",
"valyl-trna synthetase, mitochondrial (drosophila melanogaster)",
"valyl-trna synthetase 1 (mus musculus)",
"valyl-trna synthetase... | Given the context 'A fragment of the cDNA encoding a rat valyl-tRNA synthetase (TrsVal)-like protein was cloned from a rat cDNA library in lambda gt11 using an oligodeoxyribonucleotide (oligo) probe.', answer the user's query. |
What is the biomedical concept corresponding to 'calmodulin-like protein clp'? | [
"clp (homo sapiens) (calmodulin like 3 (homo sapiens))",
"calmodulin like 3 (homo sapiens)"
] | [
"calmodulin like 4 (homo sapiens)",
"calml2 (homo sapiens) (calmodulin 1 (homo sapiens))",
"calmodulin-like protein;ef-hand domain-containing protein (caenorhabditis elegans)",
"calmodulin like 5 (homo sapiens)",
"calmodulin like 6 (homo sapiens)",
"cal (drosophila melanogaster) (calmodulin (drosophila me... | Given the context 'Localization of the intronless gene coding for calmodulin-like protein CLP to human chromosome 10p13-ter.
', answer the user's query. |
What is the biomedical concept corresponding to 'calmodulin-like protein'? | [
"calmodulin like 3 (homo sapiens)"
] | [
"calmodulin (drosophila melanogaster)",
"cam (drosophila melanogaster) (calmodulin (drosophila melanogaster))",
"calmodulin 1 (homo sapiens)",
"cam (homo sapiens) (calmodulin 1 (homo sapiens))",
"calml2 (homo sapiens) (calmodulin 1 (homo sapiens))",
"cal (drosophila melanogaster) (calmodulin (drosophila m... | Given the context 'The functional intronless gene coding for a calmodulin-like protein (CLP) has been localized to human chromosome 10p13-ter.', answer the user's query. |
What is the biomedical concept corresponding to 'cytochrome p-450 family 4'? | [
"cytochrome p450 family 4 subfamily f member 3 (homo sapiens)",
"cyp4f (homo sapiens)"
] | [
"cytochrome p450 family 4 subfamily f member 8 (homo sapiens)",
"cytochrome p450 family 4 subfamily f member 12 (homo sapiens)",
"cytochrome p450 family 4 subfamily f member 2 (homo sapiens)",
"p1-450 (homo sapiens)",
"4p1 (drosophila melanogaster) (cytochrome p450 4p1 (drosophila melanogaster))",
"cytoch... | Given the context 'A novel form of cytochrome P-450 family 4 in human polymorphonuclear leukocytes.', answer the user's query. |
What is the biomedical concept corresponding to 'leukotriene b4 omega-hydroxylase'? | [
"ltb4h (homo sapiens)",
"cyp4f (homo sapiens)",
"cyp4f3 (homo sapiens)"
] | [
"arachidonate 5-lipoxygenase (homo sapiens)",
"leukotriene-b(4) omega-hydroxylase 2-like (bos taurus)",
"leukotriene c4 synthase (homo sapiens)",
"arachidonate 15-lipoxygenase type b (homo sapiens)",
"12-lox (homo sapiens) (arachidonate 15-lipoxygenase (homo sapiens))",
"leukotriene a4 hydrolase (homo sap... | Given the context 'cDNA cloning and expression of leukotriene B4 omega-hydroxylase.
', answer the user's query. |
What is the biomedical concept corresponding to 'leukotriene b4 (ltb4) omega-hydroxylase'? | [
"cyp4f (homo sapiens)",
"ltb4h (homo sapiens)",
"cyp4f3 (homo sapiens)"
] | [
"arachidonate 5-lipoxygenase (homo sapiens)",
"leukotriene-b(4) omega-hydroxylase 2-like (bos taurus)",
"cyp4a11 (homo sapiens)",
"cytochrome p450 family 4 subfamily f member 12 (homo sapiens)",
"12-lox (homo sapiens) (arachidonate 15-lipoxygenase (homo sapiens))",
"cytochrome p450 714a1-like (glycine max... | Given the context 'Isolation of cDNA clones for human leukotriene B4 (LTB4) omega-hydroxylase clearly demonstrates that the hydroxylase is a member of the cytochrome P-450 (CYP) superfamily.', answer the user's query. |
What is the biomedical concept corresponding to 'ltb4 omega-hydroxylase'? | [
"ltb4h (homo sapiens)",
"cyp4f (homo sapiens)",
"cyp4f3 (homo sapiens)"
] | [
"arachidonate 5-lipoxygenase (homo sapiens)",
"cyp4a11 (homo sapiens)",
"cyp4f2 (homo sapiens)",
"cytochrome p450, family 4, subfamily f, polypeptide 5 (rattus norvegicus)",
"cyp4e4 (drosophila melanogaster)",
"leukotriene-b(4) omega-hydroxylase 2-like (bos taurus)",
"arachidonate 15-lipoxygenase type b... | Given the context 'The microsomes from yeast cells transfected with an expression vector pAAH5 carrying isolated cDNA catalyzed the omega-hydroxylation of LTB4 with a Km value of 0.71 microM, and its activity was significantly inhibited by carbon monoxide and by antisera against CYP4A4, consistent with the properties previously reported with LTB4 omega-hydroxylase in human polymorphonuclear leukocytes.', answer the user's query. |
What is the biomedical concept corresponding to 'ltb4 omega-hydroxylase'? | [
"ltb4h (homo sapiens)",
"cyp4f (homo sapiens)",
"cyp4f3 (homo sapiens)"
] | [
"arachidonate 5-lipoxygenase (homo sapiens)",
"cyp4a11 (homo sapiens)",
"cyp4f2 (homo sapiens)",
"cytochrome p450, family 4, subfamily f, polypeptide 5 (rattus norvegicus)",
"cyp4e4 (drosophila melanogaster)",
"leukotriene-b(4) omega-hydroxylase 2-like (bos taurus)",
"arachidonate 15-lipoxygenase type b... | Given the context 'The amino acid sequence of LTB4 omega-hydroxylase (P-450LTB omega) shows 31-44% similarity to those of CYP4A, CYP4B, and CYP4C, whereas less than 25% similarity was observed with any of the other P-450 families.', answer the user's query. |
What is the biomedical concept corresponding to 'catalytic subunit of human dna polymerase epsilon'? | [
"dna polymerase epsilon, catalytic subunit (homo sapiens)"
] | [
"dna polymerase epsilon catalytic subunit (caenorhabditis elegans)",
"polymerase (dna directed), epsilon (mus musculus)",
"dna polymerase epsilon 2, accessory subunit (homo sapiens)",
"dna polymerase epsilon subunit 1 (drosophila melanogaster)",
"dna polymerase epsilon 3, accessory subunit (homo sapiens)",
... | Given the context 'Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase epsilon.
', answer the user's query. |
What is the biomedical concept corresponding to 'catalytic polypeptide of human dna polymerase epsilon'? | [
"dna polymerase epsilon, catalytic subunit (homo sapiens)"
] | [
"dna polymerase epsilon catalytic subunit (caenorhabditis elegans)",
"polymerase (dna directed), epsilon (mus musculus)",
"dna polymerase epsilon 2, accessory subunit (homo sapiens)",
"dna polymerase epsilon subunit 1 (drosophila melanogaster)",
"dna polymerase epsilon subunit 2 (drosophila melanogaster)",
... | Given the context 'The cDNA encoding the catalytic polypeptide of human DNA polymerase epsilon was cloned.', answer the user's query. |
What is the biomedical concept corresponding to 'beta-subunit of the human electron-transfer flavoprotein'? | [
"electron transfer flavoprotein subunit beta (homo sapiens)",
"madd (homo sapiens) (electron transfer flavoprotein subunit beta (homo sapiens))",
"etfb (homo sapiens)"
] | [
"electron transfer flavoprotein beta subunit (drosophila melanogaster)",
"electron transferring flavoprotein, beta polypeptide (mus musculus)",
"electron transfer flavoprotein subunit beta (xenopus tropicalis)",
"electron transfer flavoprotein subunit alpha (homo sapiens)",
"electron transfer flavoprotein s... | Given the context 'cDNA cloning and mitochondrial import of the beta-subunit of the human electron-transfer flavoprotein.
', answer the user's query. |
What is the biomedical concept corresponding to 'beta-subunit of human electron-transferring flavoprotein'? | [
"electron transfer flavoprotein subunit beta (homo sapiens)",
"madd (homo sapiens) (electron transfer flavoprotein subunit beta (homo sapiens))",
"etfb (homo sapiens)"
] | [
"electron transfer flavoprotein beta subunit (drosophila melanogaster)",
"electron transferring flavoprotein, beta polypeptide (mus musculus)",
"electron transfer flavoprotein subunit beta (xenopus tropicalis)",
"electron transfer flavoprotein subunit alpha (homo sapiens)",
"electron transfer flavoprotein s... | Given the context 'We have isolated a cDNA clone which encodes the entire beta-subunit of human electron-transferring flavoprotein (ETF) by screening an expression library from human liver using polyclonal antibodies against porcine ETF.', answer the user's query. |
What is the biomedical concept corresponding to 'beta-etf'? | [
"etfb (homo sapiens)"
] | [
"etf (homo sapiens)",
"etf (drosophila melanogaster)",
"etfb (drosophila melanogaster)",
"etf1 (homo sapiens)",
"etfrf1 (homo sapiens)",
"etf3a (homo sapiens)",
"elf 1 beta (drosophila melanogaster)",
"et-b (homo sapiens)",
"et-2 (homo sapiens)",
"ecgf-beta (homo sapiens)"
] | Given the context 'This cDNA encodes a protein of 255 amino-acid residues with a predicted molecular mass of 27,877 Da which shows a high degree of similarity with partial amino-acid sequences obtained from both rat liver and Paracoccus denitrificans beta-ETF.', answer the user's query. |
What is the biomedical concept corresponding to 'beta-etf'? | [
"etfb (homo sapiens)"
] | [
"etf (homo sapiens)",
"etf (drosophila melanogaster)",
"etfb (drosophila melanogaster)",
"etf1 (homo sapiens)",
"etfrf1 (homo sapiens)",
"etf3a (homo sapiens)",
"elf 1 beta (drosophila melanogaster)",
"et-b (homo sapiens)",
"et-2 (homo sapiens)",
"ecgf-beta (homo sapiens)"
] | Given the context 'Northern-blot analysis shows that the human beta-ETF mRNA is approximately 1 kb in size and is abundant in liver, heart and skeletal muscle.', answer the user's query. |
What is the biomedical concept corresponding to 'beta-etf'? | [
"etfb (homo sapiens)"
] | [
"etf (homo sapiens)",
"etf (drosophila melanogaster)",
"etfb (drosophila melanogaster)",
"etf1 (homo sapiens)",
"etfrf1 (homo sapiens)",
"etf3a (homo sapiens)",
"elf 1 beta (drosophila melanogaster)",
"et-b (homo sapiens)",
"et-2 (homo sapiens)",
"ecgf-beta (homo sapiens)"
] | Given the context 'Incubation with intact mitochondria indicates that the cDNA-encoded beta-ETF polypeptide contains the information necessary to reach the mitochondrial matrix.', answer the user's query. |
What is the biomedical concept corresponding to 'beta-etf'? | [
"etfb (homo sapiens)"
] | [
"etf (homo sapiens)",
"etf (drosophila melanogaster)",
"etfb (drosophila melanogaster)",
"etf1 (homo sapiens)",
"etfrf1 (homo sapiens)",
"etf3a (homo sapiens)",
"elf 1 beta (drosophila melanogaster)",
"et-b (homo sapiens)",
"et-2 (homo sapiens)",
"ecgf-beta (homo sapiens)"
] | Given the context 'These data are in agreement with previous experiments suggesting that beta-ETF, unlike the majority of nuclear-encoded mitochondrial matrix proteins, does not have a cleavable leader peptide.', answer the user's query. |
What is the biomedical concept corresponding to 'beta-etf'? | [
"etfb (homo sapiens)"
] | [
"etf (homo sapiens)",
"etf (drosophila melanogaster)",
"etfb (drosophila melanogaster)",
"etf1 (homo sapiens)",
"etfrf1 (homo sapiens)",
"etf3a (homo sapiens)",
"elf 1 beta (drosophila melanogaster)",
"et-b (homo sapiens)",
"et-2 (homo sapiens)",
"ecgf-beta (homo sapiens)"
] | Given the context 'Interestingly, the sequence analysis of beta-ETF protein identifies a 26.3% identity with the Fix A gene product of the nitrogen-fixing bacterium Azorhizobium caulinodans.', answer the user's query. |
What is the biomedical concept corresponding to 'fkbp12'? | [
"fkbp-12 (homo sapiens)",
"fkbp12 (homo sapiens) (fkbp prolyl isomerase 1a (homo sapiens))",
"fkbp1 (homo sapiens)"
] | [
"fkbp12 (drosophila melanogaster)",
"fk506-binding protein 12kd (drosophila melanogaster)",
"fkbp12.6 (homo sapiens)",
"fkbp11 (homo sapiens)",
"fkbp12 (xenopus laevis) (fkbp prolyl isomerase 1a s homeolog (xenopus laevis))",
"fkbp10 (homo sapiens)",
"fkbp prolyl isomerase 11 (homo sapiens)",
"fkbp13 ... | Given the context 'Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.
', answer the user's query. |
What is the biomedical concept corresponding to 'fkbp12'? | [
"fkbp-12 (homo sapiens)",
"fkbp12 (homo sapiens) (fkbp prolyl isomerase 1a (homo sapiens))",
"fkbp1 (homo sapiens)"
] | [
"fkbp12 (drosophila melanogaster)",
"fk506-binding protein 12kd (drosophila melanogaster)",
"fkbp12.6 (homo sapiens)",
"fkbp11 (homo sapiens)",
"fkbp12 (xenopus laevis) (fkbp prolyl isomerase 1a s homeolog (xenopus laevis))",
"fkbp10 (homo sapiens)",
"fkbp prolyl isomerase 11 (homo sapiens)",
"fkbp13 ... | Given the context 'CaN is the target of the immunosuppressive drugs cyclosporin A and FK506, which inhibit CaN after forming complexes with cytoplasmic binding proteins (cyclophilin and FKBP12, respectively).', answer the user's query. |
What is the biomedical concept corresponding to 'fkbp12'? | [
"fkbp-12 (homo sapiens)",
"fkbp12 (homo sapiens) (fkbp prolyl isomerase 1a (homo sapiens))",
"fkbp1 (homo sapiens)"
] | [
"fkbp12 (drosophila melanogaster)",
"fk506-binding protein 12kd (drosophila melanogaster)",
"fkbp12.6 (homo sapiens)",
"fkbp11 (homo sapiens)",
"fkbp12 (xenopus laevis) (fkbp prolyl isomerase 1a s homeolog (xenopus laevis))",
"fkbp10 (homo sapiens)",
"fkbp prolyl isomerase 11 (homo sapiens)",
"fkbp13 ... | Given the context 'We report here the crystal structures of full-length human CaN at 2.1 A resolution and of the complex of human CaN with FKBP12-FK506 at 3.5 A resolution.', answer the user's query. |
What is the biomedical concept corresponding to 'fkbp12'? | [
"fkbp-12 (homo sapiens)",
"fkbp12 (homo sapiens) (fkbp prolyl isomerase 1a (homo sapiens))",
"fkbp1 (homo sapiens)"
] | [
"fkbp12 (drosophila melanogaster)",
"fk506-binding protein 12kd (drosophila melanogaster)",
"fkbp12.6 (homo sapiens)",
"fkbp11 (homo sapiens)",
"fkbp12 (xenopus laevis) (fkbp prolyl isomerase 1a s homeolog (xenopus laevis))",
"fkbp10 (homo sapiens)",
"fkbp prolyl isomerase 11 (homo sapiens)",
"fkbp13 ... | Given the context 'In the FKBP12-FK506-CaN complex, the auto-inhibitory element is displaced from the active site.', answer the user's query. |
What is the biomedical concept corresponding to 'fkbp12'? | [
"fkbp-12 (homo sapiens)",
"fkbp12 (homo sapiens) (fkbp prolyl isomerase 1a (homo sapiens))",
"fkbp1 (homo sapiens)"
] | [
"fkbp12 (drosophila melanogaster)",
"fk506-binding protein 12kd (drosophila melanogaster)",
"fkbp12.6 (homo sapiens)",
"fkbp11 (homo sapiens)",
"fkbp12 (xenopus laevis) (fkbp prolyl isomerase 1a s homeolog (xenopus laevis))",
"fkbp10 (homo sapiens)",
"fkbp prolyl isomerase 11 (homo sapiens)",
"fkbp13 ... | Given the context 'The site of binding of FKBP12-FK506 appears to be shared by other non-competitive inhibitors of calcineurin, including a natural anchoring protein.', answer the user's query. |
What is the biomedical concept corresponding to 'hcc-1'? | [
"hcc-1 (homo sapiens)",
"hcc-3 (homo sapiens)",
"hcc-1/hcc-3 (homo sapiens)"
] | [
"hccs-1 (homo sapiens)",
"hcc-8 (homo sapiens)",
"hcc2 (homo sapiens)",
"hcc3 (homo sapiens)",
"hcca1 (homo sapiens)",
"hcc5 (homo sapiens)",
"hcc1 (drosophila melanogaster)",
"hcc8 (homo sapiens)",
"hccs-5 (homo sapiens)",
"hccs1 (homo sapiens)"
] | Given the context 'HCC-1, a novel chemokine from human plasma.
', answer the user's query. |
What is the biomedical concept corresponding to 'hcc-1'? | [
"hcc-1 (homo sapiens)",
"hcc-3 (homo sapiens)",
"hcc-1/hcc-3 (homo sapiens)"
] | [
"hccs-1 (homo sapiens)",
"hcc-8 (homo sapiens)",
"hcc2 (homo sapiens)",
"hcc3 (homo sapiens)",
"hcca1 (homo sapiens)",
"hcc5 (homo sapiens)",
"hcc1 (drosophila melanogaster)",
"hcc8 (homo sapiens)",
"hccs-5 (homo sapiens)",
"hccs1 (homo sapiens)"
] | Given the context 'A novel CC chemokine, HCC-1, was isolated from the hemofiltrate of patients with chronic renal failure.', answer the user's query. |
What is the biomedical concept corresponding to 'hcc-1'? | [
"hcc-1 (homo sapiens)",
"hcc-3 (homo sapiens)",
"hcc-1/hcc-3 (homo sapiens)"
] | [
"hccs-1 (homo sapiens)",
"hcc-8 (homo sapiens)",
"hcc2 (homo sapiens)",
"hcc3 (homo sapiens)",
"hcca1 (homo sapiens)",
"hcc5 (homo sapiens)",
"hcc1 (drosophila melanogaster)",
"hcc8 (homo sapiens)",
"hccs-5 (homo sapiens)",
"hccs1 (homo sapiens)"
] | Given the context 'HCC-1 has a relative molecular mass of 8,673 and consists of 74 amino acids including four cysteines linked to disulfide bonds.', answer the user's query. |
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