instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'Secondary alcohols and 3 beta-hydroxysteroids were inactive with sigma-ADH or were oxidized with very low efficiency.', select the correct biomedical concept corresponding to 'sigma-adh'. Answer using one of the provided options. | <Options>: A: alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus) (aka alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide)
B: alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh2)
C: alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh3)
D: alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens) (aka alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide)
E: adh1 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh1)
F: None of the above. | D |
<Instruct>: Given the context 'The KM of sigma-ADH for ethanol was 25 mM, and the KM for primary straight chain alcohols decreased substantially as chain length increased.', select the correct biomedical concept corresponding to 'sigma-adh'. Answer using one of the provided options. | <Options>: A: alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus) (aka alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide)
B: alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh3)
C: alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens) (aka alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide)
D: alcohol dehydrogenase adh5 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh5)
E: alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh1)
F: None of the above. | C |
<Instruct>: Given the context 'The KM of sigma-ADH for ethanol was 25 mM, and the KM for primary straight chain alcohols decreased substantially as chain length increased.', select the correct biomedical concept corresponding to 'sigma-adh'. Answer using one of the provided options. | <Options>: A: alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh2)
B: alcohol dehydrogenase 1a (class i), alpha polypeptide (homo sapiens) (aka alcohol dehydrogenase 1a (class i), alpha polypeptide)
C: alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh3)
D: alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (mus musculus) (aka alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide)
E: adh1 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh1)
F: None of the above. | F |
<Instruct>: Given the context 'There are important amino acid differences in the alcohol-binding site between the human class IV (sigma) and human class I (beta) alcohol dehydrogenases that appear to explain the high catalytic efficiency for all-trans-retinol, the high kcat for ethanol, and the low catalytic efficiency for secondary alcohols of sigma-ADH relative to beta 1-ADH.', select the correct biomedical concept corresponding to 'class iv (sigma)'. Answer using one of the provided options. | <Options>: A: sigma5 (mus musculus) (aka adaptor-related protein 5 complex, sigma 1 subunit)
B: sigma1c (homo sapiens) (aka adaptor related protein complex 1 subunit sigma 3)
C: sigma1r (homo sapiens) (aka sigma non-opioid intracellular receptor 1)
D: sigma3a (homo sapiens) (aka adaptor related protein complex 3 subunit sigma 1)
E: sigma1a (homo sapiens) (aka adaptor related protein complex 1 subunit sigma 1)
F: None of the above. | F |
<Instruct>: Given the context 'There are important amino acid differences in the alcohol-binding site between the human class IV (sigma) and human class I (beta) alcohol dehydrogenases that appear to explain the high catalytic efficiency for all-trans-retinol, the high kcat for ethanol, and the low catalytic efficiency for secondary alcohols of sigma-ADH relative to beta 1-ADH.', select the correct biomedical concept corresponding to 'class i (beta) alcohol dehydrogenases'. Answer using one of the provided options. | <Options>: A: alcohol dehydrogenase 4 (class ii), pi polypeptide (homo sapiens) (aka alcohol dehydrogenase 4 (class ii), pi polypeptide)
B: alcohol dehydrogenase 1a (class i), alpha polypeptide (homo sapiens) (aka alcohol dehydrogenase 1a (class i), alpha polypeptide)
C: adh1b (bos taurus) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
D: adh1b (homo sapiens) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
E: alcohol dehydrogenase 1b (class i), beta polypeptide (xenopus tropicalis) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
F: None of the above. | D |
<Instruct>: Given the context 'There are important amino acid differences in the alcohol-binding site between the human class IV (sigma) and human class I (beta) alcohol dehydrogenases that appear to explain the high catalytic efficiency for all-trans-retinol, the high kcat for ethanol, and the low catalytic efficiency for secondary alcohols of sigma-ADH relative to beta 1-ADH.', select the correct biomedical concept corresponding to 'sigma-adh'. Answer using one of the provided options. | <Options>: A: alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh1)
B: alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (mus musculus) (aka alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide)
C: alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens) (aka alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide)
D: alcohol dehydrogenase adh5 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh5)
E: alcohol dehydrogenase 1a (class i), alpha polypeptide (homo sapiens) (aka alcohol dehydrogenase 1a (class i), alpha polypeptide)
F: None of the above. | C |
<Instruct>: Given the context 'There are important amino acid differences in the alcohol-binding site between the human class IV (sigma) and human class I (beta) alcohol dehydrogenases that appear to explain the high catalytic efficiency for all-trans-retinol, the high kcat for ethanol, and the low catalytic efficiency for secondary alcohols of sigma-ADH relative to beta 1-ADH.', select the correct biomedical concept corresponding to 'beta 1-adh'. Answer using one of the provided options. | <Options>: A: alcohol dehydrogenase 1a (class i), alpha polypeptide (homo sapiens) (aka alcohol dehydrogenase 1a (class i), alpha polypeptide)
B: alcohol dehydrogenase 1b (class i), beta polypeptide (xenopus tropicalis) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
C: alcohol dehydrogenase 1b (class i), beta polypeptide (bos taurus) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
D: adh1b (homo sapiens) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
E: adh1b promoter (homo sapiens) (aka adh1b promoter)
F: None of the above. | D |
<Instruct>: Given the context 'For example, modeling the binding of all-trans-retinol in the human beta 1-ADH structure suggested that coordination of retinol to the active-site zinc is hindered by a loop from residues 114 to 120 that is at the entrance to the alcohol-binding site.', select the correct biomedical concept corresponding to 'beta 1-adh'. Answer using one of the provided options. | <Options>: A: alcohol dehydrogenase 1b (class i), beta polypeptide (xenopus tropicalis) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
B: adh1b (bos taurus) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
C: adh1b (homo sapiens) (aka alcohol dehydrogenase 1b (class i), beta polypeptide)
D: adh1b promoter (homo sapiens) (aka adh1b promoter)
E: adh1 (homo sapiens) (aka alcohol dehydrogenase 1a (class i), alpha polypeptide)
F: None of the above. | C |
<Instruct>: Given the context 'The deletion of Gly-117 in human sigma-ADH and a substitution of Leu for the bulky Tyr-110 appear to facilitate retinol access to the active-site zinc.', select the correct biomedical concept corresponding to 'sigma-adh'. Answer using one of the provided options. | <Options>: A: adh1 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh1)
B: adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)) (aka alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide)
C: alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh3)
D: alcohol dehydrogenase 1a (class i), alpha polypeptide (homo sapiens) (aka alcohol dehydrogenase 1a (class i), alpha polypeptide)
E: alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c) (aka alcohol dehydrogenase adh2)
F: None of the above. | B |
<Instruct>: Given the context 'The first 240 nucleotides in the 5' untranslated region of type I acetyl-CoA-carboxylase mRNA replace the first 100 nucleotides of the (G + C)-rich region of the 5' untranslated region of the type II mRNA.', select the correct biomedical concept corresponding to 'type i acetyl-coa-carboxylase'. Answer using one of the provided options. | <Options>: A: acc1 (homo sapiens) (acetyl-coa carboxylase alpha (homo sapiens)) (aka acetyl-coa carboxylase alpha)
B: acc-1 (homo sapiens) (aka bcl2 related protein a1)
C: acetoacetyl-coa synthetase (homo sapiens) (aka acetoacetyl-coa synthetase)
D: acetyl-coa carboxylase 1 (arabidopsis thaliana) (aka acetyl-coa carboxylase 1)
E: acetyl-coa carboxylase beta (homo sapiens) (aka acetyl-coa carboxylase beta)
F: None of the above. | A |
<Instruct>: Given the context 'Human mu opiate receptor.', select the correct biomedical concept corresponding to 'mu opiate receptor'. Answer using one of the provided options. | <Options>: A: opioid receptor mu 1 (homo sapiens) (aka opioid receptor mu 1)
B: opioid related nociceptin receptor 1 (rattus norvegicus) (aka opioid related nociceptin receptor 1)
C: opr (mus musculus) (aka zinc finger protein of the cerebellum 5)
D: opioid receptor, mu 1 (mus musculus) (aka opioid receptor, mu 1)
E: opioid related nociceptin receptor 1 (homo sapiens) (aka opioid related nociceptin receptor 1)
F: None of the above. | A |
<Instruct>: Given the context 'A human mu opiate receptor cDNA has been identified from a cerebral cortical cDNA library using sequences from the rat mu opiate receptor cDNA.', select the correct biomedical concept corresponding to 'mu opiate receptor'. Answer using one of the provided options. | <Options>: A: opioid related nociceptin receptor 1 (rattus norvegicus) (aka opioid related nociceptin receptor 1)
B: opioid receptor mu 1 (homo sapiens) (aka opioid receptor mu 1)
C: opr (mus musculus) (aka zinc finger protein of the cerebellum 5)
D: oprm1 (mus musculus) (aka opioid receptor, mu 1)
E: opioid related nociceptin receptor 1 (homo sapiens) (aka opioid related nociceptin receptor 1)
F: None of the above. | B |
<Instruct>: Given the context 'A human mu opiate receptor cDNA has been identified from a cerebral cortical cDNA library using sequences from the rat mu opiate receptor cDNA.', select the correct biomedical concept corresponding to 'mu opiate receptor'. Answer using one of the provided options. | <Options>: A: opioid receptor-like 1 (mus musculus) (aka opioid receptor-like 1)
B: opr (mus musculus) (aka zinc finger protein of the cerebellum 5)
C: opioid related nociceptin receptor 1 (rattus norvegicus) (aka opioid related nociceptin receptor 1)
D: opioid related nociceptin receptor 1 (homo sapiens) (aka opioid related nociceptin receptor 1)
E: opioid growth factor receptor (mus musculus) (aka opioid growth factor receptor)
F: None of the above. | C |
<Instruct>: Given the context 'A human mu opiate receptor cDNA has been identified from a cerebral cortical cDNA library using sequences from the rat mu opiate receptor cDNA.', select the correct biomedical concept corresponding to 'mu opiate receptor'. Answer using one of the provided options. | <Options>: A: opioid receptor mu 1 (homo sapiens) (aka opioid receptor mu 1)
B: opioid receptor, mu 1 (mus musculus) (aka opioid receptor, mu 1)
C: opr (mus musculus) (aka zinc finger protein of the cerebellum 5)
D: opioid receptor-like 1 (mus musculus) (aka opioid receptor-like 1)
E: opioid receptor, mu 1 (rattus norvegicus) (aka opioid receptor, mu 1)
F: None of the above. | F |
<Instruct>: Given the context 'The human mu opiate receptor (h mu OR1) shares 95% amino acid identity with the rat sequence.', select the correct biomedical concept corresponding to 'mu opiate receptor'. Answer using one of the provided options. | <Options>: A: opioid receptor, mu 1 (rattus norvegicus) (aka opioid receptor, mu 1)
B: opioid receptor mu 1 (homo sapiens) (aka opioid receptor mu 1)
C: nop (mus musculus) (opioid receptor-like 1 (mus musculus)) (aka opioid receptor-like 1)
D: oprm1 (mus musculus) (aka opioid receptor, mu 1)
E: opioid growth factor receptor (mus musculus) (aka opioid growth factor receptor)
F: None of the above. | B |
<Instruct>: Given the context 'The human mu opiate receptor (h mu OR1) shares 95% amino acid identity with the rat sequence.', select the correct biomedical concept corresponding to 'h mu or1'. Answer using one of the provided options. | <Options>: A: or10h1 (mus musculus) (aka olfactory receptor family 10 subfamily h member 1)
B: or51h1 (mus musculus) (aka olfactory receptor family 51 subfamily h member 1)
C: m-or-1 (homo sapiens) (aka opioid receptor mu 1)
D: or1m1 (mus musculus) (aka olfactory receptor family 1 subfamily m member 1)
E: or1n1 (mus musculus) (aka olfactory receptor family 1 subfamily n member 1)
F: None of the above. | C |
<Instruct>: Given the context 'The expressed mu OR1 recognized tested opiate drugs and opioid peptides in a sodium- and GTP-sensitive fashion with affinities virtually identical to those displayed by the rat mu opiate receptor.', select the correct biomedical concept corresponding to 'mu or1'. Answer using one of the provided options. | <Options>: A: or1n1 (mus musculus) (aka olfactory receptor family 1 subfamily n member 1)
B: or1r1 (mus musculus) (aka olfactory receptor family 1 subfamily jrmember 1)
C: or-1 (mus musculus) (aka nuclear receptor subfamily 1, group h, member 2)
D: orm-1 (mus musculus) (aka orosomucoid 1)
E: or1a1 (mus musculus) (aka olfactory receptor family 1 subfamily a member 1)
F: None of the above. | F |
<Instruct>: Given the context 'The expressed mu OR1 recognized tested opiate drugs and opioid peptides in a sodium- and GTP-sensitive fashion with affinities virtually identical to those displayed by the rat mu opiate receptor.', select the correct biomedical concept corresponding to 'mu opiate receptor'. Answer using one of the provided options. | <Options>: A: opr (mus musculus) (aka zinc finger protein of the cerebellum 5)
B: opioid related nociceptin receptor 1 (homo sapiens) (aka opioid related nociceptin receptor 1)
C: opioid related nociceptin receptor 1 (rattus norvegicus) (aka opioid related nociceptin receptor 1)
D: opioid receptor, mu 1 (mus musculus) (aka opioid receptor, mu 1)
E: opioid receptor-like 1 (mus musculus) (aka opioid receptor-like 1)
F: None of the above. | C |
<Instruct>: Given the context 'Effects on cyclic AMP are similar to those noted for the rat mu opiate receptor.', select the correct biomedical concept corresponding to 'mu opiate receptor'. Answer using one of the provided options. | <Options>: A: opr (mus musculus) (aka zinc finger protein of the cerebellum 5)
B: opioid receptor mu 1 (homo sapiens) (aka opioid receptor mu 1)
C: opioid related nociceptin receptor 1 (rattus norvegicus) (aka opioid related nociceptin receptor 1)
D: nop (mus musculus) (opioid receptor-like 1 (mus musculus)) (aka opioid receptor-like 1)
E: opioid growth factor receptor (mus musculus) (aka opioid growth factor receptor)
F: None of the above. | C |
<Instruct>: Given the context 'An 18 kb genomic clone hybridizing with the h mu OR1 cDNA contains 63 and 489 bp exonic sequences flanked by splice donor/acceptor sequences.', select the correct biomedical concept corresponding to 'h mu or1'. Answer using one of the provided options. | <Options>: A: m-or-1 (homo sapiens) (aka opioid receptor mu 1)
B: or10h1 (mus musculus) (aka olfactory receptor family 10 subfamily h member 1)
C: or1m1 (homo sapiens) (aka olfactory receptor family 1 subfamily m member 1)
D: m-or-1 (mus musculus) (aka opioid receptor, mu 1)
E: or-1 (mus musculus) (aka nuclear receptor subfamily 1, group h, member 2)
F: None of the above. | A |
<Instruct>: Given the context 'Human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild-type and Cys129 mutant enzymes.
', select the correct biomedical concept corresponding to 'cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme a synthase'. Answer using one of the provided options. | <Options>: A: 3-hydroxy-3-methylglutaryl-coenzyme a synthase, related sequence 1 (mus musculus) (aka 3-hydroxy-3-methylglutaryl-coenzyme a synthase, related sequence 1)
B: 3-hydroxy-3-methylglutaryl-coenzyme a synthase 2 (mus musculus) (aka 3-hydroxy-3-methylglutaryl-coenzyme a synthase 2)
C: 3-oxoacyl-acp synthase, mitochondrial (homo sapiens) (aka 3-oxoacyl-acp synthase, mitochondrial)
D: 3-hydroxy-3-methylglutaryl-coenzyme a synthase 1 (soluble) pseudogene (homo sapiens) (aka 3-hydroxy-3-methylglutaryl-coenzyme a synthase 1 (soluble) pseudogene)
E: 3-hydroxy-3-methylglutaryl-coa synthase 1 (homo sapiens) (aka 3-hydroxy-3-methylglutaryl-coa synthase 1)
F: None of the above. | E |
<Instruct>: Given the context 'A cDNA for the human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase (EC 4.1.3.5) was subcloned and expressed from a T7-based vector in Escherichia coli.', select the correct biomedical concept corresponding to 'cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme a (hmg-coa) synthase'. Answer using one of the provided options. | <Options>: A: hmgcs (homo sapiens) (aka 3-hydroxy-3-methylglutaryl-coa synthase 1)
B: 3-hydroxy-3-methylglutaryl-coa lyase (homo sapiens) (aka 3-hydroxy-3-methylglutaryl-coa lyase)
C: 3-hydroxy-3-methylglutaryl-coenzyme a synthase 1 (mus musculus) (aka 3-hydroxy-3-methylglutaryl-coenzyme a synthase 1)
D: 3-oxoacyl-acp synthase, mitochondrial (homo sapiens) (aka 3-oxoacyl-acp synthase, mitochondrial)
E: 3-hydroxy-3-methylglutaryl-coa synthase 2 (homo sapiens) (aka 3-hydroxy-3-methylglutaryl-coa synthase 2)
F: None of the above. | A |
<Instruct>: Given the context 'Association between atopy and variants of the beta subunit of the high-affinity immunoglobulin E receptor.
', select the correct biomedical concept corresponding to 'beta subunit of the high-affinity immunoglobulin e receptor'. Answer using one of the provided options. | <Options>: A: cd79b molecule (bos taurus) (aka cd79b molecule)
B: endothelin receptor type b (homo sapiens) (aka endothelin receptor type b)
C: estrogen related receptor beta (bos taurus) (aka estrogen related receptor beta)
D: cd99b (homo sapiens) (aka cd99 molecule like 2)
E: er-beta (homo sapiens) (aka estrogen receptor 2)
F: None of the above. | F |
<Instruct>: Given the context 'The beta-subunit of the high-affinity IgE receptor (Fc epsilon RI-beta) on chromosome 11 is maternally linked to atopy, the state of enhanced IgE responsiveness underlying allergic asthma and rhinitis.', select the correct biomedical concept corresponding to 'beta-subunit of the high-affinity ige receptor'. Answer using one of the provided options. | <Options>: A: igb (homo sapiens) (aka cd79b molecule)
B: cd179b (homo sapiens) (aka immunoglobulin lambda like polypeptide 1)
C: cd99b (homo sapiens) (aka cd99 molecule like 2)
D: cd79b (bos taurus) (aka cd79b molecule)
E: cd1b (homo sapiens) (aka cd1b molecule)
F: None of the above. | F |
<Instruct>: Given the context 'The beta-subunit of the high-affinity IgE receptor (Fc epsilon RI-beta) on chromosome 11 is maternally linked to atopy, the state of enhanced IgE responsiveness underlying allergic asthma and rhinitis.', select the correct biomedical concept corresponding to 'beta-subunit of the high-affinity ige receptor'. Answer using one of the provided options. | <Options>: A: cd179b (homo sapiens) (aka immunoglobulin lambda like polypeptide 1)
B: cd79b (bos taurus) (aka cd79b molecule)
C: cd1b (homo sapiens) (aka cd1b molecule)
D: cd99b (homo sapiens) (aka cd99 molecule like 2)
E: igb (homo sapiens) (aka cd79b molecule)
F: None of the above. | F |
<Instruct>: Given the context 'The beta-subunit of the high-affinity IgE receptor (Fc epsilon RI-beta) on chromosome 11 is maternally linked to atopy, the state of enhanced IgE responsiveness underlying allergic asthma and rhinitis.', select the correct biomedical concept corresponding to 'fc epsilon ri-beta'. Answer using one of the provided options. | <Options>: A: cd64b (homo sapiens) (aka fc gamma receptor ib, pseudogene)
B: fc epsilon receptor ii (homo sapiens) (aka fc epsilon receptor ii)
C: fcgammariia (homo sapiens) (aka fc gamma receptor iia)
D: fcgammariic (homo sapiens) (aka fc gamma receptor iic (gene/pseudogene))
E: fc gamma receptor iib (homo sapiens) (aka fc gamma receptor iib)
F: None of the above. | F |
<Instruct>: Given the context 'We have identified a common variant of Fc epsilon RI-beta, lle181Leu within the 4th transmembrane domain.', select the correct biomedical concept corresponding to 'fc epsilon ri-beta'. Answer using one of the provided options. | <Options>: A: fcriiib (homo sapiens) (aka fc gamma receptor iiib)
B: fcgriib (homo sapiens) (aka fc gamma receptor iib)
C: fcgammariia (homo sapiens) (aka fc gamma receptor iia)
D: cd64b (homo sapiens) (aka fc gamma receptor ib, pseudogene)
E: fc epsilon receptor ii (homo sapiens) (aka fc epsilon receptor ii)
F: None of the above. | F |
<Instruct>: Given the context 'Our data indicate that Fc epsilon RI-beta, subject to maternal modification, may be the atopy-causing locus on chromosome 11q.', select the correct biomedical concept corresponding to 'fc epsilon ri-beta'. Answer using one of the provided options. | <Options>: A: fcriiib (homo sapiens) (aka fc gamma receptor iiib)
B: fc epsilon receptor ii (homo sapiens) (aka fc epsilon receptor ii)
C: fcgammariia (homo sapiens) (aka fc gamma receptor iia)
D: cd64b (homo sapiens) (aka fc gamma receptor ib, pseudogene)
E: fcgriib (homo sapiens) (aka fc gamma receptor iib)
F: None of the above. | F |
<Instruct>: Given the context 'Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism.
', select the correct biomedical concept corresponding to 'thyrotropin receptor'. Answer using one of the provided options. | <Options>: A: tshr (homo sapiens) (aka thyroid stimulating hormone receptor)
B: thyrotropin releasing hormone receptor (rattus norvegicus) (aka thyrotropin releasing hormone receptor)
C: thyroid stimulating hormone receptor (rattus norvegicus) (aka thyroid stimulating hormone receptor)
D: thyrotropin releasing hormone receptor (homo sapiens) (aka thyrotropin releasing hormone receptor)
E: thyrotropin-releasing hormone receptor (bos taurus) (aka thyrotropin-releasing hormone receptor)
F: None of the above. | A |
<Instruct>: Given the context 'The thyrotropin receptor (TSHR), a member of the large family of G protein-coupled receptors, controls both the function and growth of thyroid cells via stimulation of adenylyl cyclase.', select the correct biomedical concept corresponding to 'thyrotropin receptor'. Answer using one of the provided options. | <Options>: A: thyrotropin releasing hormone receptor (bos taurus) (aka thyrotropin releasing hormone receptor)
B: thyrotropin-releasing hormone receptor (bos taurus) (aka thyrotropin-releasing hormone receptor)
C: thyrotropin releasing hormone receptor (rattus norvegicus) (aka thyrotropin releasing hormone receptor)
D: thyrotropin releasing hormone receptor (gallus gallus) (aka thyrotropin releasing hormone receptor)
E: thyroid stimulating hormone receptor (homo sapiens) (aka thyroid stimulating hormone receptor)
F: None of the above. | E |
<Instruct>: Given the context 'The thyrotropin receptor (TSHR), a member of the large family of G protein-coupled receptors, controls both the function and growth of thyroid cells via stimulation of adenylyl cyclase.', select the correct biomedical concept corresponding to 'tshr'. Answer using one of the provided options. | <Options>: A: thyrotropin releasing hormone receptor (bos taurus) (aka thyrotropin releasing hormone receptor)
B: tshb (homo sapiens) (aka thyroid stimulating hormone subunit beta)
C: thyrotropin-releasing hormone receptor (bos taurus) (aka thyrotropin-releasing hormone receptor)
D: tshr (homo sapiens) (aka thyroid stimulating hormone receptor)
E: tshr (bos taurus) (aka thyroid stimulating hormone receptor)
F: None of the above. | D |
<Instruct>: Given the context 'We report two different mutations in the TSHR gene of affected members of two large pedigrees with non-autoimmune autosomal dominant hyperthyroidism (toxic thyroid hyperplasia), that involve residues in the third (Val509Ala) and seventh (Cys672Tyr) transmembrane segments.', select the correct biomedical concept corresponding to 'tshr'. Answer using one of the provided options. | <Options>: A: tshr (bos taurus) (aka thyroid stimulating hormone receptor)
B: ghrhr (homo sapiens) (aka growth hormone releasing hormone receptor)
C: tshr (homo sapiens) (aka thyroid stimulating hormone receptor)
D: tshr (rattus norvegicus) (aka thyroid stimulating hormone receptor)
E: tshb (homo sapiens) (aka thyroid stimulating hormone subunit beta)
F: None of the above. | C |
<Instruct>: Given the context 'X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene.
', select the correct biomedical concept corresponding to 'l1'. Answer using one of the provided options. | <Options>: A: l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster)) (aka lethal (1) l1)
B: cell adhesion molecule l1-like (xenopus tropicalis) (aka cell adhesion molecule l1-like)
C: adhesion g protein-coupled receptor l1 (homo sapiens) (aka adhesion g protein-coupled receptor l1)
D: cyclin l1 (homo sapiens) (aka cyclin l1)
E: l1 cell adhesion molecule (homo sapiens) (aka l1 cell adhesion molecule)
F: None of the above. | E |
<Instruct>: Given the context 'We have previously shown that X-linked hydrocephalus is caused by mutations in the gene for neural cell adhesion molecule L1 (L1CAM), an axonal glycoprotein involved in neuronal migration and differentiation.', select the correct biomedical concept corresponding to 'neural cell adhesion molecule l1'. Answer using one of the provided options. | <Options>: A: cell adhesion molecule l1 like (homo sapiens) (aka cell adhesion molecule l1 like)
B: n-cam-l1 (mus musculus) (aka l1 cell adhesion molecule)
C: l1 cell adhesion molecule (homo sapiens) (aka l1 cell adhesion molecule)
D: cell adhesion molecule l1-like (rattus norvegicus) (aka cell adhesion molecule l1-like)
E: neural cell adhesion molecule 1 (homo sapiens) (aka neural cell adhesion molecule 1)
F: None of the above. | C |
<Instruct>: Given the context 'We have previously shown that X-linked hydrocephalus is caused by mutations in the gene for neural cell adhesion molecule L1 (L1CAM), an axonal glycoprotein involved in neuronal migration and differentiation.', select the correct biomedical concept corresponding to 'l1cam'. Answer using one of the provided options. | <Options>: A: l1cam (gallus gallus) (aka l1 cell adhesion molecule)
B: l1 cell adhesion molecule (homo sapiens) (aka l1 cell adhesion molecule)
C: l1cam (mus musculus) (aka l1 cell adhesion molecule)
D: cell adhesion molecule l1 like (homo sapiens) (aka cell adhesion molecule l1 like)
E: None of the above. | B |
<Instruct>: Given the context 'We have previously shown that X-linked hydrocephalus is caused by mutations in the gene for neural cell adhesion molecule L1 (L1CAM), an axonal glycoprotein involved in neuronal migration and differentiation.', select the correct biomedical concept corresponding to 'l1cam'. Answer using one of the provided options. | <Options>: A: l1cam (gallus gallus) (aka l1 cell adhesion molecule)
B: n-cam-l1 (mus musculus) (aka l1 cell adhesion molecule)
C: cell adhesion molecule l1 like (homo sapiens) (aka cell adhesion molecule l1 like)
D: None of the above. | D |
<Instruct>: Given the context 'Here we report mutations of the L1 gene in MASA syndrome and SPG1, in addition to HSAS families.', select the correct biomedical concept corresponding to 'l1'. Answer using one of the provided options. | <Options>: A: cell adhesion molecule l1-like (xenopus tropicalis) (aka cell adhesion molecule l1-like)
B: adhesion g protein-coupled receptor l1 (homo sapiens) (aka adhesion g protein-coupled receptor l1)
C: cyclin l1 (homo sapiens) (aka cyclin l1)
D: l1 cell adhesion molecule (homo sapiens) (aka l1 cell adhesion molecule)
E: l1.1 (mus musculus) (aka skull morphology 1)
F: None of the above. | D |
<Instruct>: Given the context 'Two of the HSAS mutations would abolish cell surface expression of L1 and represent the first functional null mutations in this disorder.', select the correct biomedical concept corresponding to 'l1'. Answer using one of the provided options. | <Options>: A: adhesion g protein-coupled receptor l1 (homo sapiens) (aka adhesion g protein-coupled receptor l1)
B: l1 cell adhesion molecule (homo sapiens) (aka l1 cell adhesion molecule)
C: l1 (drosophila melanogaster) (retroactive (drosophila melanogaster)) (aka retroactive)
D: l1 cell adhesion molecule (xenopus tropicalis) (aka l1 cell adhesion molecule)
E: cell adhesion molecule l1-like (xenopus tropicalis) (aka cell adhesion molecule l1-like)
F: None of the above. | B |
<Instruct>: Given the context 'Our results indicate that these three syndromes from part of a clinical spectrum resulting from a heterogeneous group of mutations in the L1 gene.', select the correct biomedical concept corresponding to 'l1'. Answer using one of the provided options. | <Options>: A: l1 cell adhesion molecule (xenopus tropicalis) (aka l1 cell adhesion molecule)
B: l1 cell adhesion molecule (homo sapiens) (aka l1 cell adhesion molecule)
C: l1 (drosophila melanogaster) (retroactive (drosophila melanogaster)) (aka retroactive)
D: lethal (1) l1 (drosophila melanogaster) (aka lethal (1) l1)
E: cell adhesion molecule l1-like (xenopus tropicalis) (aka cell adhesion molecule l1-like)
F: None of the above. | B |
<Instruct>: Given the context 'Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zeta.
Bradykinin exerts a broad spectrum of cellular effects on different tissues.', select the correct biomedical concept corresponding to 'bradykinin'. Answer using one of the provided options. | <Options>: A: bradykinin receptor b1 (homo sapiens) (aka bradykinin receptor b1)
B: kininogen 1 (bos taurus) (aka kininogen 1)
C: bradykinin (xenopus tropicalis) (aka bradykinin receptor b2)
D: bk (homo sapiens) (aka kininogen 1)
E: bradykinin (xenopus laevis) (bradykinin receptor b2 s homeolog (xenopus laevis)) (aka bradykinin receptor b2 s homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zeta.
Bradykinin exerts a broad spectrum of cellular effects on different tissues.', select the correct biomedical concept corresponding to 'bradykinin'. Answer using one of the provided options. | <Options>: A: bk (homo sapiens) (aka kininogen 1)
B: kallikrein 1 (bos taurus) (aka kallikrein 1)
C: kallikrein (homo sapiens) (aka kallikrein related peptidase 4)
D: bradykinin receptor b2 (homo sapiens) (aka bradykinin receptor b2)
E: kallikrein b1 (bos taurus) (aka kallikrein b1)
F: None of the above. | A |
<Instruct>: Given the context 'It is believed that these effects are predominantly mediated by the recently cloned B2 receptor.', select the correct biomedical concept corresponding to 'b2 receptor'. Answer using one of the provided options. | <Options>: A: bkb1r (homo sapiens) (aka bradykinin receptor b1)
B: bb2r (homo sapiens) (aka gastrin releasing peptide receptor)
C: adrb2 (homo sapiens) (aka adrenoceptor beta 2)
D: blr2 (homo sapiens) (aka c-c motif chemokine receptor 7)
E: bdkrb2 (homo sapiens) (aka bradykinin receptor b2)
F: None of the above. | E |
<Instruct>: Given the context 'Involvement of protein kinase C (PKC) was suggested and activation of the classical PKC isoforms alpha and beta was recently demonstrated.', select the correct biomedical concept corresponding to 'pkc isoforms alpha'. Answer using one of the provided options. | <Options>: A: protein kinase c, alpha (xenopus tropicalis) (aka protein kinase c, alpha)
B: protein kinase c iota (homo sapiens) (aka protein kinase c iota)
C: pkc-alpha (homo sapiens) (aka protein kinase c alpha)
D: prkaa (homo sapiens) (aka protein kinase amp-activated catalytic subunit alpha 2)
E: prkaca (homo sapiens) (protein kinase camp-activated catalytic subunit alpha (homo sapiens)) (aka protein kinase camp-activated catalytic subunit alpha)
F: None of the above. | C |
<Instruct>: Given the context 'The aim of the present study was to investigate whether the B2 receptor also activates new (delta, epsilon) and atypical (zeta) PKC isoforms.', select the correct biomedical concept corresponding to 'b2 receptor'. Answer using one of the provided options. | <Options>: A: blr2 (homo sapiens) (aka c-c motif chemokine receptor 7)
B: adrb2r (homo sapiens) (aka adrenoceptor beta 2)
C: bkb1r (homo sapiens) (aka bradykinin receptor b1)
D: bdkrb2 (homo sapiens) (aka bradykinin receptor b2)
E: bb2r (homo sapiens) (aka gastrin releasing peptide receptor)
F: None of the above. | D |
<Instruct>: Given the context 'To investigate this, chinese hamster ovary (CHO) cells, stably transfected with human B2 receptor, were used.', select the correct biomedical concept corresponding to 'b2 receptor'. Answer using one of the provided options. | <Options>: A: bb2r (homo sapiens) (aka gastrin releasing peptide receptor)
B: b2ar (homo sapiens) (aka adrenoceptor beta 2)
C: bkr2 (homo sapiens) (aka bradykinin receptor b2)
D: blr2 (homo sapiens) (aka c-c motif chemokine receptor 7)
E: bkb1r (homo sapiens) (aka bradykinin receptor b1)
F: None of the above. | C |
<Instruct>: Given the context 'Stimulation of the cells with bradykinin resulted in a rapid (30-60 s) translocation of the PKC isoforms alpha, epsilon, and zeta.', select the correct biomedical concept corresponding to 'bradykinin'. Answer using one of the provided options. | <Options>: A: kininogen 1 (bos taurus) (aka kininogen 1)
B: kallikrein b1 (bos taurus) (aka kallikrein b1)
C: kallikrein 1 (bos taurus) (aka kallikrein 1)
D: bk (homo sapiens) (aka kininogen 1)
E: kallikrein b1 (homo sapiens) (aka kallikrein b1)
F: None of the above. | D |
<Instruct>: Given the context 'Stimulation of the cells with bradykinin resulted in a rapid (30-60 s) translocation of the PKC isoforms alpha, epsilon, and zeta.', select the correct biomedical concept corresponding to 'bradykinin'. Answer using one of the provided options. | <Options>: A: kallikrein (homo sapiens) (aka kallikrein related peptidase 4)
B: bradykinin receptor b2 (homo sapiens) (aka bradykinin receptor b2)
C: kallikrein b1 (bos taurus) (aka kallikrein b1)
D: kallikrein b1 (homo sapiens) (aka kallikrein b1)
E: bradykinin (xenopus tropicalis) (aka bradykinin receptor b2)
F: None of the above. | F |
<Instruct>: Given the context 'Translocation of PKC delta was not detected.', select the correct biomedical concept corresponding to 'pkc delta'. Answer using one of the provided options. | <Options>: A: pkcd (drosophila melanogaster) (aka protein kinase c delta)
B: pkcd (homo sapiens) (aka protein kinase c delta)
C: protein kinase c delta (xenopus tropicalis) (aka protein kinase c delta)
D: protein kinase c delta (bos taurus) (aka protein kinase c delta)
E: None of the above. | B |
<Instruct>: Given the context 'The effect of bradykinin was reduced by simultaneous addition of the receptor antagonist HOE 140, a bradykinin-related decapeptide.', select the correct biomedical concept corresponding to 'bradykinin'. Answer using one of the provided options. | <Options>: A: kallikrein b1 (homo sapiens) (aka kallikrein b1)
B: bk (homo sapiens) (aka kininogen 1)
C: bradykinin receptor b2 (homo sapiens) (aka bradykinin receptor b2)
D: kallikrein (homo sapiens) (aka kallikrein related peptidase 4)
E: kininogen 1 (bos taurus) (aka kininogen 1)
F: None of the above. | B |
<Instruct>: Given the context 'The effect of bradykinin was reduced by simultaneous addition of the receptor antagonist HOE 140, a bradykinin-related decapeptide.', select the correct biomedical concept corresponding to 'bradykinin'. Answer using one of the provided options. | <Options>: A: kallikrein b1 (bos taurus) (aka kallikrein b1)
B: bradykinin (xenopus tropicalis) (aka bradykinin receptor b2)
C: bk (homo sapiens) (aka kininogen 1)
D: bradykinin (xenopus laevis) (bradykinin receptor b2 s homeolog (xenopus laevis)) (aka bradykinin receptor b2 s homeolog)
E: kallikrein b1 (homo sapiens) (aka kallikrein b1)
F: None of the above. | C |
<Instruct>: Given the context 'The data show that the B2 receptor in this cell model is able to activate, in addition to the classical PKC isoform alpha, the new PKC isoform epsilon and the atypical PKC isoform zeta.', select the correct biomedical concept corresponding to 'b2 receptor'. Answer using one of the provided options. | <Options>: A: bkr2 (homo sapiens) (aka bradykinin receptor b2)
B: bkb1r (homo sapiens) (aka bradykinin receptor b1)
C: bb2r (homo sapiens) (aka gastrin releasing peptide receptor)
D: blr2 (homo sapiens) (aka c-c motif chemokine receptor 7)
E: b2ar (homo sapiens) (aka adrenoceptor beta 2)
F: None of the above. | A |
<Instruct>: Given the context 'The data show that the B2 receptor in this cell model is able to activate, in addition to the classical PKC isoform alpha, the new PKC isoform epsilon and the atypical PKC isoform zeta.', select the correct biomedical concept corresponding to 'pkc isoform alpha'. Answer using one of the provided options. | <Options>: A: prkaa (homo sapiens) (aka protein kinase amp-activated catalytic subunit alpha 2)
B: pkn-alpha (homo sapiens) (aka protein kinase n1)
C: protein kinase c, alpha (xenopus tropicalis) (aka protein kinase c, alpha)
D: prkaca (homo sapiens) (protein kinase camp-activated catalytic subunit alpha (homo sapiens)) (aka protein kinase camp-activated catalytic subunit alpha)
E: pkcalpha (homo sapiens) (aka protein kinase c alpha)
F: None of the above. | E |
<Instruct>: Given the context 'The data show that the B2 receptor in this cell model is able to activate, in addition to the classical PKC isoform alpha, the new PKC isoform epsilon and the atypical PKC isoform zeta.', select the correct biomedical concept corresponding to 'pkc isoform epsilon'. Answer using one of the provided options. | <Options>: A: pkce (homo sapiens) (aka protein kinase c epsilon)
B: protein kinase c, epsilon (rattus norvegicus) (aka protein kinase c, epsilon)
C: protein kinase c epsilon (bos taurus) (aka protein kinase c epsilon)
D: protein kinase c epsilon (sus scrofa) (aka protein kinase c epsilon)
E: protein kinase c, epsilon (mus musculus) (aka protein kinase c, epsilon)
F: None of the above. | A |
<Instruct>: Given the context 'The data show that the B2 receptor in this cell model is able to activate, in addition to the classical PKC isoform alpha, the new PKC isoform epsilon and the atypical PKC isoform zeta.', select the correct biomedical concept corresponding to 'pkc isoform zeta'. Answer using one of the provided options. | <Options>: A: pkc-zeta (homo sapiens) (aka protein kinase c zeta)
B: protein kinase c, zeta (rattus norvegicus) (aka protein kinase c, zeta)
C: pkc-zeta (xenopus laevis) (protein kinase c zeta l homeolog (xenopus laevis)) (aka protein kinase c zeta l homeolog)
D: protein kinase c, zeta (mus musculus) (aka protein kinase c, zeta)
E: protein kinase c zeta (xenopus tropicalis) (aka protein kinase c zeta)
F: None of the above. | A |
<Instruct>: Given the context 'In this cell system similar results on PKC alpha, epsilon, and zeta were observed, suggesting that all three PKC isoforms are involved in signal transduction of the B2 receptor.', select the correct biomedical concept corresponding to 'b2 receptor'. Answer using one of the provided options. | <Options>: A: b2r (homo sapiens) (aka bradykinin receptor b2)
B: bb2r (homo sapiens) (aka gastrin releasing peptide receptor)
C: bkb1r (homo sapiens) (aka bradykinin receptor b1)
D: b2ar (homo sapiens) (aka adrenoceptor beta 2)
E: blr2 (homo sapiens) (aka c-c motif chemokine receptor 7)
F: None of the above. | A |
<Instruct>: Given the context 'Protein structure of fetal antigen 1 (FA1).', select the correct biomedical concept corresponding to 'fetal antigen 1'. Answer using one of the provided options. | <Options>: A: mage family member f1 (homo sapiens) (aka mage family member f1)
B: atrial fibrillation, familial 1 (homo sapiens) (aka atrial fibrillation, familial 1)
C: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
D: fet1 (homo sapiens) (aka dopamine receptor d3)
E: fetal and adult testis expressed 1 (homo sapiens) (aka fetal and adult testis expressed 1)
F: None of the above. | F |
<Instruct>: Given the context 'Protein structure of fetal antigen 1 (FA1).', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
B: fa1 (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
C: faf (homo sapiens) (fa complementation group f (homo sapiens)) (aka fa complementation group f)
D: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
E: fa complementation group i (homo sapiens) (aka fa complementation group i)
F: None of the above. | F |
<Instruct>: Given the context 'Protein structure of fetal antigen 1 (FA1).', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: faf1 (homo sapiens) (aka fas associated factor 1)
B: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
C: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
D: fa (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
E: fa complementation group i (homo sapiens) (aka fa complementation group i)
F: None of the above. | F |
<Instruct>: Given the context 'A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2.
', select the correct biomedical concept corresponding to 'dlk'. Answer using one of the provided options. | <Options>: A: dlk-1 (homo sapiens) (aka delta like non-canonical notch ligand 1)
B: dlk/zpk (drosophila melanogaster) (aka wallenda)
C: dlg (drosophila melanogaster) (discs large 1 (drosophila melanogaster)) (aka discs large 1)
D: dlk (drosophila melanogaster) (leucokinin (drosophila melanogaster)) (aka leucokinin)
E: dlk2 (homo sapiens) (aka delta like non-canonical notch ligand 2)
F: None of the above. | A |
<Instruct>: Given the context 'A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2.
', select the correct biomedical concept corresponding to 'pg2'. Answer using one of the provided options. | <Options>: A: pgk2 (homo sapiens) (phosphoglycerate kinase 1, pseudogene 2 (homo sapiens)) (aka phosphoglycerate kinase 1, pseudogene 2)
B: pg2 (mus musculus) (aka delta like non-canonical notch ligand 1)
C: polygalacturonase pg2 (glycine max) (aka polygalacturonase pg2)
D: pg2 (homo sapiens) (aka delta like non-canonical notch ligand 1)
E: phosphoglycerate kinase 2 (homo sapiens) (aka phosphoglycerate kinase 2)
F: None of the above. | D |
<Instruct>: Given the context 'The present paper describes the primary structure, glycosylation and tissue localization of fetal antigen 1 (FA1) isolated from second-trimester human amniotic fluid.', select the correct biomedical concept corresponding to 'fetal antigen 1'. Answer using one of the provided options. | <Options>: A: fetal and adult testis expressed 1 (homo sapiens) (aka fetal and adult testis expressed 1)
B: fet1 (homo sapiens) (aka dopamine receptor d3)
C: mage family member f1 (homo sapiens) (aka mage family member f1)
D: fam1a (homo sapiens) (aka metallophosphoesterase domain containing 1)
E: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
F: None of the above. | F |
<Instruct>: Given the context 'The present paper describes the primary structure, glycosylation and tissue localization of fetal antigen 1 (FA1) isolated from second-trimester human amniotic fluid.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fa complementation group f (homo sapiens) (aka fa complementation group f)
B: faf1 (homo sapiens) (aka fas associated factor 1)
C: fa (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
D: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
E: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
F: None of the above. | F |
<Instruct>: Given the context 'FA1 is a single-chained, heterogeneous glycoprotein of 225-262 amino acid residues.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fa complementation group i (homo sapiens) (aka fa complementation group i)
B: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
C: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
D: faf1 (homo sapiens) (aka fas associated factor 1)
E: faf (homo sapiens) (fa complementation group f (homo sapiens)) (aka fa complementation group f)
F: None of the above. | F |
<Instruct>: Given the context 'FA1 has six well conserved epidermal-growth-factor motifs and contains up to ten O-glycosylation and N-glycosylation sites, six of which are differentially glycosylated.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
B: faf1 (homo sapiens) (aka fas associated factor 1)
C: faf (homo sapiens) (fa complementation group f (homo sapiens)) (aka fa complementation group f)
D: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
E: fah (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
F: None of the above. | F |
<Instruct>: Given the context 'Alignment to the translated sequences of Mus. musculus dlk and human dlk revealed 86% and 99% identity, respectively, to a 259-amino-acid residue overlap, and this high similarity extends with minor corrections to the human adrenal-specific mRNA, pG2 as well.', select the correct biomedical concept corresponding to 'dlk'. Answer using one of the provided options. | <Options>: A: dlk (drosophila melanogaster) (leucokinin (drosophila melanogaster)) (aka leucokinin)
B: dlk2 (homo sapiens) (aka delta like non-canonical notch ligand 2)
C: dlg (drosophila melanogaster) (discs large 2 (drosophila melanogaster)) (aka discs large 2)
D: dlk1 (homo sapiens) (aka delta like non-canonical notch ligand 1)
E: dlk/zpk (drosophila melanogaster) (aka wallenda)
F: None of the above. | D |
<Instruct>: Given the context 'Alignment to the translated sequences of Mus. musculus dlk and human dlk revealed 86% and 99% identity, respectively, to a 259-amino-acid residue overlap, and this high similarity extends with minor corrections to the human adrenal-specific mRNA, pG2 as well.', select the correct biomedical concept corresponding to 'dlk'. Answer using one of the provided options. | <Options>: A: dlk-2 (homo sapiens) (aka delta like non-canonical notch ligand 2)
B: dlk1 (homo sapiens) (aka delta like non-canonical notch ligand 1)
C: dlk (drosophila melanogaster) (leucokinin (drosophila melanogaster)) (aka leucokinin)
D: dlak (drosophila melanogaster) (aka i-kappab kinase beta)
E: dlg (drosophila melanogaster) (discs large 2 (drosophila melanogaster)) (aka discs large 2)
F: None of the above. | B |
<Instruct>: Given the context 'Alignment to the translated sequences of Mus. musculus dlk and human dlk revealed 86% and 99% identity, respectively, to a 259-amino-acid residue overlap, and this high similarity extends with minor corrections to the human adrenal-specific mRNA, pG2 as well.', select the correct biomedical concept corresponding to 'pg2'. Answer using one of the provided options. | <Options>: A: pgk2 (homo sapiens) (phosphoglycerate kinase 1, pseudogene 2 (homo sapiens)) (aka phosphoglycerate kinase 1, pseudogene 2)
B: phosphoglycerate kinase 2 (homo sapiens) (aka phosphoglycerate kinase 2)
C: pgap2 (homo sapiens) (aka post-gpi attachment to proteins 2)
D: pg2 (homo sapiens) (aka delta like non-canonical notch ligand 1)
E: pgm2 (homo sapiens) (aka phosphoglucomutase 2)
F: None of the above. | D |
<Instruct>: Given the context 'Immunohistochemical analysis demonstrated the presence of FA1 in 10 out of 14 lung tumors containing neuroendocrine elements, and in the placental villi where FA1 was exclusively seen in stromal cells in close contact to the vascular structure.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
B: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
C: fa (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
D: faf1 (homo sapiens) (aka fas associated factor 1)
E: faf (homo sapiens) (fa complementation group f (homo sapiens)) (aka fa complementation group f)
F: None of the above. | F |
<Instruct>: Given the context 'Immunohistochemical analysis demonstrated the presence of FA1 in 10 out of 14 lung tumors containing neuroendocrine elements, and in the placental villi where FA1 was exclusively seen in stromal cells in close contact to the vascular structure.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fa (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
B: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
C: fa complementation group i (homo sapiens) (aka fa complementation group i)
D: faf1 (homo sapiens) (aka fas associated factor 1)
E: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
F: None of the above. | F |
<Instruct>: Given the context 'Immunohistochemical analysis demonstrated the presence of FA1 in 10 out of 14 lung tumors containing neuroendocrine elements, and in the placental villi where FA1 was exclusively seen in stromal cells in close contact to the vascular structure.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: faf1 (homo sapiens) (aka fas associated factor 1)
B: fa complementation group i (homo sapiens) (aka fa complementation group i)
C: faf (homo sapiens) (fa complementation group f (homo sapiens)) (aka fa complementation group f)
D: fah (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
E: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
F: None of the above. | F |
<Instruct>: Given the context 'In the pancreas, FA1 co-localized with insulin in the insulin secretory granules of the beta cells within the islets of Langerhans.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
B: fa complementation group f (homo sapiens) (aka fa complementation group f)
C: faf1 (homo sapiens) (aka fas associated factor 1)
D: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
E: fa1 (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
F: None of the above. | F |
<Instruct>: Given the context 'Our findings suggest that FA1 is synthesized as a membrane anchored protein and released into the circulation after enzymic cleavage, and that circulating FA1 represents the post-translationally modified gene product of human dlk which, in turn, is identical to human adrenal-specific mRNA pG2.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fa complementation group i (homo sapiens) (aka fa complementation group i)
B: fa complementation group f (homo sapiens) (aka fa complementation group f)
C: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
D: faf1 (homo sapiens) (aka fas associated factor 1)
E: fa-1 (homo sapiens) (aka small nuclear ribonucleoprotein 13)
F: None of the above. | F |
<Instruct>: Given the context 'Our findings suggest that FA1 is synthesized as a membrane anchored protein and released into the circulation after enzymic cleavage, and that circulating FA1 represents the post-translationally modified gene product of human dlk which, in turn, is identical to human adrenal-specific mRNA pG2.', select the correct biomedical concept corresponding to 'fa1'. Answer using one of the provided options. | <Options>: A: fah (homo sapiens) (fa complementation group a (homo sapiens)) (aka fa complementation group a)
B: fa complementation group f (homo sapiens) (aka fa complementation group f)
C: faf1 (homo sapiens) (aka fas associated factor 1)
D: fah1 (homo sapiens) (aka fatty acid 2-hydroxylase)
E: fa complementation group i (homo sapiens) (aka fa complementation group i)
F: None of the above. | F |
<Instruct>: Given the context 'Our findings suggest that FA1 is synthesized as a membrane anchored protein and released into the circulation after enzymic cleavage, and that circulating FA1 represents the post-translationally modified gene product of human dlk which, in turn, is identical to human adrenal-specific mRNA pG2.', select the correct biomedical concept corresponding to 'dlk'. Answer using one of the provided options. | <Options>: A: dlk (drosophila melanogaster) (leucokinin (drosophila melanogaster)) (aka leucokinin)
B: dlg (drosophila melanogaster) (discs large 2 (drosophila melanogaster)) (aka discs large 2)
C: dlk2 (homo sapiens) (aka delta like non-canonical notch ligand 2)
D: dlak (drosophila melanogaster) (aka i-kappab kinase beta)
E: dlk-1 (homo sapiens) (aka delta like non-canonical notch ligand 1)
F: None of the above. | E |
<Instruct>: Given the context 'Our findings suggest that FA1 is synthesized as a membrane anchored protein and released into the circulation after enzymic cleavage, and that circulating FA1 represents the post-translationally modified gene product of human dlk which, in turn, is identical to human adrenal-specific mRNA pG2.', select the correct biomedical concept corresponding to 'pg2'. Answer using one of the provided options. | <Options>: A: phosphoglycerate kinase 2 (homo sapiens) (aka phosphoglycerate kinase 2)
B: pg2 (homo sapiens) (aka delta like non-canonical notch ligand 1)
C: pgm2 (homo sapiens) (aka phosphoglucomutase 2)
D: pg2 (mus musculus) (aka delta like non-canonical notch ligand 1)
E: pgdp2 (homo sapiens) (aka phosphogluconate dehydrogenase pseudogene 2)
F: None of the above. | B |
<Instruct>: Given the context 'Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen.
', select the correct biomedical concept corresponding to 'dna helicase ii'. Answer using one of the provided options. | <Options>: A: dnah2 (homo sapiens) (aka dynein axonemal heavy chain 2)
B: dbp2 (homo sapiens) (aka deah-box helicase 16)
C: damage specific dna binding protein 2 (homo sapiens) (aka damage specific dna binding protein 2)
D: chd2 (homo sapiens) (chromodomain helicase dna binding protein 2 (homo sapiens)) (aka chromodomain helicase dna binding protein 2)
E: dna replication helicase/nuclease 2 (homo sapiens) (aka dna replication helicase/nuclease 2)
F: None of the above. | F |
<Instruct>: Given the context 'Human DNA helicase II (HDH II) is a novel ATP-dependent DNA unwinding enzyme, purified to apparent homogeneity from HeLa cells, which (i) unwinds exclusively DNA duplexes, (ii) prefers partially unwound substrates and (iii) proceeds in the 3' to 5' direction on the bound strand.', select the correct biomedical concept corresponding to 'dna helicase ii'. Answer using one of the provided options. | <Options>: A: dnah2 (homo sapiens) (aka dynein axonemal heavy chain 2)
B: dna helicase ii (escherichia coli str. k-12 substr. mg1655) (aka dna helicase ii)
C: chromodomain helicase dna binding protein 2 (homo sapiens) (aka chromodomain helicase dna binding protein 2)
D: dna helicase b (homo sapiens) (aka dna helicase b)
E: dnase2 (homo sapiens) (aka deoxyribonuclease 2, lysosomal)
F: None of the above. | F |
<Instruct>: Given the context 'Human DNA helicase II (HDH II) is a novel ATP-dependent DNA unwinding enzyme, purified to apparent homogeneity from HeLa cells, which (i) unwinds exclusively DNA duplexes, (ii) prefers partially unwound substrates and (iii) proceeds in the 3' to 5' direction on the bound strand.', select the correct biomedical concept corresponding to 'hdh ii'. Answer using one of the provided options. | <Options>: A: cphd2 (homo sapiens) (aka prop paired-like homeobox 1)
B: d2h (homo sapiens) (aka solute carrier family 3 member 1)
C: hyd2 (homo sapiens) (aka hypodontia 2 (autosomal recessive))
D: hd2 (homo sapiens) (aka histone deacetylase 2)
E: dcoh2 (homo sapiens) (aka pterin-4 alpha-carbinolamine dehydratase 2)
F: None of the above. | F |
<Instruct>: Given the context 'HDH II is a heterodimer of 72 and 87 kDa polypeptides.', select the correct biomedical concept corresponding to 'hdh ii'. Answer using one of the provided options. | <Options>: A: dnah2 (homo sapiens) (aka dynein axonemal heavy chain 2)
B: hd2 (homo sapiens) (aka histone deacetylase 2)
C: d2h (homo sapiens) (aka solute carrier family 3 member 1)
D: phd2 (homo sapiens) (aka egl-9 family hypoxia inducible factor 1)
E: cphd2 (homo sapiens) (aka prop paired-like homeobox 1)
F: None of the above. | F |
<Instruct>: Given the context 'HDH II is a heterodimer of 72 and 87 kDa polypeptides.', select the correct biomedical concept corresponding to 'hdh ii'. Answer using one of the provided options. | <Options>: A: dcoh2 (homo sapiens) (aka pterin-4 alpha-carbinolamine dehydratase 2)
B: hdhd2 (homo sapiens) (aka haloacid dehalogenase like hydrolase domain containing 2)
C: d2h (homo sapiens) (aka solute carrier family 3 member 1)
D: phd2 (homo sapiens) (aka egl-9 family hypoxia inducible factor 1)
E: hd2 (homo sapiens) (aka histone deacetylase 2)
F: None of the above. | F |
<Instruct>: Given the context 'HDH II is a heterodimer of 72 and 87 kDa polypeptides.', select the correct biomedical concept corresponding to 'heterodimer of 72 and 87 kda polypeptides'. Answer using one of the provided options. | <Options>: A: signal recognition particle 72kda (xenopus tropicalis) (aka signal recognition particle 72kda)
B: hst17287 (homo sapiens) (aka aquaporin 9)
C: fap87 (homo sapiens) (aka ankyrin 2)
D: signal recognition particle 72 (homo sapiens) (aka signal recognition particle 72)
E: rpsap72 (homo sapiens) (aka ribosomal protein sa pseudogene 72)
F: None of the above. | F |
<Instruct>: Given the context 'The antibodies raised in rabbit against either polypeptide can remove from the solution all the activities of HDH II.', select the correct biomedical concept corresponding to 'hdh ii'. Answer using one of the provided options. | <Options>: A: dcoh2 (homo sapiens) (aka pterin-4 alpha-carbinolamine dehydratase 2)
B: hdhd2 (homo sapiens) (aka haloacid dehalogenase like hydrolase domain containing 2)
C: d2h (homo sapiens) (aka solute carrier family 3 member 1)
D: dnah2 (homo sapiens) (aka dynein axonemal heavy chain 2)
E: phd2 (homo sapiens) (aka egl-9 family hypoxia inducible factor 1)
F: None of the above. | F |
<Instruct>: Given the context 'Microsequencing of the separate polypeptides of HDH II and cross-reaction with specific antibodies showed that this enzyme is identical to Ku, an autoantigen recognized by the sera of scleroderma and lupus erythematosus patients, which binds specifically to duplex DNA ends and is regulator of a DNA-dependent protein kinase.', select the correct biomedical concept corresponding to 'hdh ii'. Answer using one of the provided options. | <Options>: A: cphd2 (homo sapiens) (aka prop paired-like homeobox 1)
B: phd2 (homo sapiens) (aka egl-9 family hypoxia inducible factor 1)
C: hdhd2 (homo sapiens) (aka haloacid dehalogenase like hydrolase domain containing 2)
D: hdhd2b (homo sapiens) (aka phospholysine phosphohistidine inorganic pyrophosphate phosphatase)
E: hd2 (homo sapiens) (aka histone deacetylase 2)
F: None of the above. | F |
<Instruct>: Given the context 'Recombinant HDH II/Ku protein expressed in and purified from Escherichia coli cells showed DNA binding and helicase activities indistinguishable from those of the isolated protein.', select the correct biomedical concept corresponding to 'hdh ii/ku'. Answer using one of the provided options. | <Options>: A: kud (homo sapiens) (aka transmembrane protein 258)
B: kub1 (homo sapiens) (aka clusterin)
C: ku70/ku80 (drosophila melanogaster) (aka inverted repeat-binding protein)
D: kub2 (homo sapiens) (aka x-ray repair cross complementing 5)
E: ku70 (homo sapiens) (aka x-ray repair cross complementing 6)
F: None of the above. | D |
<Instruct>: Given the context 'The exclusively nuclear location of HDH II/Ku antigen, its highly specific affinity for double-stranded DNA, its abundance and its newly demonstrated ability to unwind exclusively DNA duplexes, point to an additional, if still unclear, role for this molecule in DNA metabolism.', select the correct biomedical concept corresponding to 'hdh ii/ku'. Answer using one of the provided options. | <Options>: A: atp-dependent dna helicase 2 subunit ku70 (glycine max) (aka atp-dependent dna helicase 2 subunit ku70)
B: kub1 (homo sapiens) (aka clusterin)
C: kub3 (homo sapiens) (aka atp23 metallopeptidase and atp synthase assembly factor homolog)
D: kub2 (homo sapiens) (aka x-ray repair cross complementing 5)
E: atp-dependent dna helicase 2 subunit ku80 (glycine max) (aka atp-dependent dna helicase 2 subunit ku80)
F: None of the above. | D |
<Instruct>: Given the context 'A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization.
', select the correct biomedical concept corresponding to 'cytokine (ik)'. Answer using one of the provided options. | <Options>: A: ik cytokine (oryctolagus cuniculus) (aka ik cytokine)
B: ik cytokine (homo sapiens) (aka ik cytokine)
C: ik cytokine l homeolog (xenopus laevis) (aka ik cytokine l homeolog)
D: ik cytokine (mus musculus) (aka ik cytokine)
E: interferon kappa (homo sapiens) (aka interferon kappa)
F: None of the above. | B |
<Instruct>: Given the context 'We have purified a cytokine (IK factor, 19 kDa) secreted by the leukemic cell line K562 and several cancer cells, which inhibits HLA Class II antigen induction by IFN-gamma.', select the correct biomedical concept corresponding to 'ik factor'. Answer using one of the provided options. | <Options>: A: iklf (mus musculus) (aka kruppel-like transcription factor 5)
B: ik cytokine (homo sapiens) (aka ik cytokine)
C: ik-1 (xenopus tropicalis) (aka ikaros family zinc finger 1)
D: ikzf1 (homo sapiens) (aka ikaros family zinc finger 1)
E: ik1 (xenopus laevis) (ikaros family zinc finger 1 s homeolog (xenopus laevis)) (aka ikaros family zinc finger 1 s homeolog)
F: None of the above. | B |
<Instruct>: Given the context 'We have purified a cytokine (IK factor, 19 kDa) secreted by the leukemic cell line K562 and several cancer cells, which inhibits HLA Class II antigen induction by IFN-gamma.', select the correct biomedical concept corresponding to 'ifn-gamma'. Answer using one of the provided options. | <Options>: A: interferon gamma (gallus gallus) (aka interferon gamma)
B: ifn-gamma (gallus gallus) (aka interferon)
C: interferon gamma (homo sapiens) (aka interferon gamma)
D: interleukin 36 gamma (homo sapiens) (aka interleukin 36 gamma)
E: interferon gamma (oryctolagus cuniculus) (aka interferon gamma)
F: None of the above. | C |
<Instruct>: Given the context 'We produced specific mAbs which antagonize the biological effect of IK in colon carcinoma Colo 205 cells induced to express HLA-DR molecules by IFN-gamma.', select the correct biomedical concept corresponding to 'ik'. Answer using one of the provided options. | <Options>: A: ik (bos taurus) (aka ik cytokine)
B: ik (drosophila melanogaster) (aka i-kappab kinase beta)
C: ik (homo sapiens) (ik cytokine (homo sapiens)) (aka ik cytokine)
D: ik (mus musculus) (aka ik cytokine)
E: ikki (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit epsilon)
F: None of the above. | C |
<Instruct>: Given the context 'We produced specific mAbs which antagonize the biological effect of IK in colon carcinoma Colo 205 cells induced to express HLA-DR molecules by IFN-gamma.', select the correct biomedical concept corresponding to 'ifn-gamma'. Answer using one of the provided options. | <Options>: A: interferon gamma (xenopus tropicalis) (aka interferon gamma)
B: interferon gamma (homo sapiens) (aka interferon gamma)
C: gmf-gamma (homo sapiens) (aka glia maturation factor gamma)
D: interferon gamma (gallus gallus) (aka interferon gamma)
E: cd3-gammaamma (homo sapiens) (aka cd3 gamma subunit of t-cell receptor complex)
F: None of the above. | B |
<Instruct>: Given the context 'We produced specific mAbs which antagonize the biological effect of IK in colon carcinoma Colo 205 cells induced to express HLA-DR molecules by IFN-gamma.', select the correct biomedical concept corresponding to 'ifn-gamma'. Answer using one of the provided options. | <Options>: A: interferon gamma (mus musculus) (aka interferon gamma)
B: interferon gamma (sus scrofa) (aka interferon gamma)
C: gmf-gamma (homo sapiens) (aka glia maturation factor gamma)
D: cd3-gammaamma (homo sapiens) (aka cd3 gamma subunit of t-cell receptor complex)
E: interleukin 36 gamma (homo sapiens) (aka interleukin 36 gamma)
F: None of the above. | F |
<Instruct>: Given the context 'Moreover, in Colo 205, HLA-DR can also be induced by the protein synthesis inhibitor Cycloheximide (0.1 micrograms ml-1); and addition of IK factor almost completely abolishes HLA class II expression.', select the correct biomedical concept corresponding to 'ik factor'. Answer using one of the provided options. | <Options>: A: iklf (homo sapiens) (aka klf transcription factor 5)
B: ik1 (xenopus laevis) (ikaros family zinc finger 1 s homeolog (xenopus laevis)) (aka ikaros family zinc finger 1 s homeolog)
C: iklf (mus musculus) (aka kruppel-like transcription factor 5)
D: ikzf1 (homo sapiens) (aka ikaros family zinc finger 1)
E: ik (homo sapiens) (ik cytokine (homo sapiens)) (aka ik cytokine)
F: None of the above. | E |
<Instruct>: Given the context 'IK gene localization shows that it maps on chromosome 2p15-p14.', select the correct biomedical concept corresponding to 'ik'. Answer using one of the provided options. | <Options>: A: ik1 (xenopus laevis) (ikaros family zinc finger 1 l homeolog (xenopus laevis)) (aka ikaros family zinc finger 1 l homeolog)
B: ik cytokine (homo sapiens) (aka ik cytokine)
C: ik (bos taurus) (aka ik cytokine)
D: ik (drosophila melanogaster) (aka i-kappab kinase beta)
E: ik (mus musculus) (aka ik cytokine)
F: None of the above. | B |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx (mus musculus) (aka bmx non-receptor tyrosine kinase)
B: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
C: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
D: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
E: bmh (xenopus tropicalis) (aka bleomycin hydrolase)
F: None of the above. | B |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'btk'. Answer using one of the provided options. | <Options>: A: blk proto-oncogene, src family tyrosine kinase (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
B: bruton tyrosine kinase (xenopus tropicalis) (aka bruton tyrosine kinase)
C: bruton tyrosine kinase (bos taurus) (aka bruton tyrosine kinase)
D: bruton tyrosine kinase (homo sapiens) (aka bruton tyrosine kinase)
E: blk (homo sapiens) (aka blk proto-oncogene, src family tyrosine kinase)
F: None of the above. | D |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'itk'. Answer using one of the provided options. | <Options>: A: itk (homo sapiens) (aka il2 inducible t cell kinase)
B: itk (danio rerio) (aka il2 inducible t cell kinase)
C: integrin linked kinase (homo sapiens) (aka integrin linked kinase)
D: itk (bos taurus) (aka il2 inducible t cell kinase)
E: ibtk (homo sapiens) (aka inhibitor of bruton tyrosine kinase)
F: None of the above. | A |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'tec'. Answer using one of the provided options. | <Options>: A: tec protein tyrosine kinase (homo sapiens) (aka tec protein tyrosine kinase)
B: tec (sus scrofa) (aka tec protein tyrosine kinase)
C: tec (xenopus laevis) (tec protein tyrosine kinase l homeolog (xenopus laevis)) (aka tec protein tyrosine kinase l homeolog)
D: tec (homo sapiens) (transient erythroblastopenia of childhood (homo sapiens)) (aka transient erythroblastopenia of childhood)
E: teck (xenopus tropicalis) (aka c-c motif chemokine ligand 25)
F: None of the above. | A |
<Instruct>: Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', select the correct biomedical concept corresponding to 'txk'. Answer using one of the provided options. | <Options>: A: txk (homo sapiens) (aka txk tyrosine kinase)
B: txk (mus musculus) (aka txk tyrosine kinase)
C: txk (danio rerio) (aka txk tyrosine kinase)
D: txk tyrosine kinase (sus scrofa) (aka txk tyrosine kinase)
E: txk tyrosine kinase (bos taurus) (aka txk tyrosine kinase)
F: None of the above. | A |
<Instruct>: Given the context 'The Bmx sequence was identified and cloned during our search for novel tyrosine kinase genes expressed in human bone marrow cells.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
B: mbx (homo sapiens) (aka diencephalon/mesencephalon homeobox 1)
C: bmh (xenopus tropicalis) (aka bleomycin hydrolase)
D: bmnx (mus musculus) (aka body mass index)
E: bmx non-receptor tyrosine kinase (homo sapiens) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', select the correct biomedical concept corresponding to 'bmx'. Answer using one of the provided options. | <Options>: A: bmx (rattus norvegicus) (aka bmx non-receptor tyrosine kinase)
B: bmx (gallus gallus) (aka bmx non-receptor tyrosine kinase)
C: bmx (homo sapiens) (aka bmx non-receptor tyrosine kinase)
D: bmx (mus musculus) (aka bmx non-receptor tyrosine kinase)
E: bmx (bos taurus) (aka bmx non-receptor tyrosine kinase)
F: None of the above. | C |
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