query stringclasses 190 values | positive listlengths 1 5 | negative listlengths 4 4 | system stringlengths 69 2.19k |
|---|---|---|---|
What is the biomedical concept corresponding to 'rat'? | [
"rats (rattus norvegicus) (rattus norvegicus)",
"rat (rattus norvegicus) (rattus norvegicus)",
"rattus norvegicus (rats (rattus norvegicus))",
"norway rat (rattus norvegicus)",
"brown rat (rattus norvegicus)"
] | [
"rats (rattus) (rattus)",
"rat (rattus) (rattus)",
"house rat (rattus rattus)",
"mus rattus (rattus rattus)"
] | Given the context 'Antibodies used for analysis of surface markers included: FITC-conjugated rat anti-mouse CD45R/B220 (RA3-6B2, BD Pharmingen San Diego, CA) for B cells; FITC-conjugated rat anti-mouse CD8α (53-6.7) and CD4 (GK1.5, BD Pharmingen, San Diego, CA) for CD8+ or CD4+ cells, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'mouse'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mouse (mus <genus>)",
"mice (mus <genus>) (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Antibodies used for analysis of surface markers included: FITC-conjugated rat anti-mouse CD45R/B220 (RA3-6B2, BD Pharmingen San Diego, CA) for B cells; FITC-conjugated rat anti-mouse CD8α (53-6.7) and CD4 (GK1.5, BD Pharmingen, San Diego, CA) for CD8+ or CD4+ cells, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'mouse'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mouse (mus <genus>)",
"mice (mus <genus>) (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Samples evaluated for CD4+ and CD8α+ cells were also incubated with biotin-conjugated hamster anti-mouse CD3e (145-2C11) monoclonal antibody (BD Pharmingen, San Diego, CA) and subsequently with streptavidin APC Cy7.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Antibody assays
Immunoglobulin subclass IgG1 and IgG2a titers in mice were determined by a whole bacterial cell ELISA performed in 96-well, Immulon 2 HB, round-bottom plates (Dynex Technologies).', answer the user's query. |
What is the biomedical concept corresponding to 'b. mallei'? | [
"malleomyces mallei (burkholderia mallei)",
"burkholderia mallei (actinobacillus mallei)",
"loefferella mallei (burkholderia mallei)",
"actinobacillus mallei (burkholderia mallei)",
"bacillus mallei (burkholderia mallei)"
] | [
"erysiphe malloti",
"mucilaginibacter mallensis",
"inocybe subg. mallocybe (mallocybe)",
"bartonella melophagi (candidatus bartonella melophagi)"
] | Given the context 'B. mallei antigen was diluted in 0.1 M carbonate buffer (pH 9.5) and 50 μl of diluted cells placed into wells.', answer the user's query. |
What is the biomedical concept corresponding to 'bovine'? | [
"bovine (bos taurus)",
"cow (bos taurus) (bos taurus)",
"bos bovis (bos taurus)",
"domestic cattle (bos taurus)",
"domestic cow (bos taurus)"
] | [
"cattle (bos)",
"bos (cattle)",
"bovidae",
"bos taurus indicus (bos indicus)"
] | Given the context 'The plates were washed with washing solution (1× PBS, 0.05% Tween 20), and incubated with 100 μl of blocking solution (1× PBS, 1% bovine serum albumin, 0.05% Tween 20) for 1 h at 37°C.', answer the user's query. |
What is the biomedical concept corresponding to 'mouse'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mouse (mus <genus>)",
"mice (mus <genus>) (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Dilutions of mouse sera were made with blocking solution in duplicate and plates were incubated for 1 h at 37°C.', answer the user's query. |
What is the biomedical concept corresponding to 'horseradish'? | [
"horseradish (armoracia rusticana)"
] | [
"horseradish tree (moringa oleifera)",
"rachis",
"horseradish tree family (moringaceae)",
"rasbora vulgaris"
] | Given the context 'Following incubation, plates were washed and 50 μl of anti-Ig-horseradish peroxidase subclass conjugate, diluted accordingly to manufacturer's instructions (Southern Biotechnology Associates, Inc.', answer the user's query. |
What is the biomedical concept corresponding to 'yeast'? | [
"saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883)",
"saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (saccharomyces cerevisiae)",
"baker's yeast (saccharomyces cerevisiae)",
"mycoderma cerevisiae (saccharomyces cerevisiae)",
"brewer's yeast (saccharomyces ce... | [
"true yeasts (saccharomycotina)",
"saccharomyces cerevisiae or paradoxus (saccharomyces cf. cerevisiae/paradoxus)",
"saccharomyces lactis (kluyveromyces lactis)",
"saccharomyces albicans (candida albicans)"
] | Given the context 'Mapping irradiation hybrids to cosmid and yeast artificial chromosome libraries by direct hybridization of Alu-PCR products.
', answer the user's query. |
What is the biomedical concept corresponding to 'yeast'? | [
"saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883)",
"saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (saccharomyces cerevisiae)",
"baker's yeast (saccharomyces cerevisiae)",
"mycoderma cerevisiae (saccharomyces cerevisiae)",
"brewer's yeast (saccharomyces ce... | [
"true yeasts (saccharomycotina)",
"saccharomyces cerevisiae or paradoxus (saccharomyces cf. cerevisiae/paradoxus)",
"saccharomyces lactis (kluyveromyces lactis)",
"saccharomyces albicans (candida albicans)"
] | Given the context 'Abstract
A direct hybridization protocol is described for screening cosmid and yeast artificial chromosome libraries with pools of Alu-PCR products from somatic cell or irradiation hybrids.', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'A series of human X chromosome irradiation hybrids were mapped by this method, using a cosmid reference library for comparisons between overlapping hybrids to identify interesting clones for further analysis.', answer the user's query. |
What is the biomedical concept corresponding to 'yeast'? | [
"saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883)",
"saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (saccharomyces cerevisiae)",
"baker's yeast (saccharomyces cerevisiae)",
"mycoderma cerevisiae (saccharomyces cerevisiae)",
"brewer's yeast (saccharomyces ce... | [
"true yeasts (saccharomycotina)",
"saccharomyces cerevisiae or paradoxus (saccharomyces cf. cerevisiae/paradoxus)",
"saccharomyces lactis (kluyveromyces lactis)",
"saccharomyces albicans (candida albicans)"
] | Given the context 'Images
Nucleic Acids Research, Vol. 19, No. 12 3315
Mapping irradiation hybrids to cosmid and yeast artificial chromosome libraries by direct hybridization of Alu-PCR products
Anthony P.Monaco*, Veronica M.S.Lam2, Gunther Zehetner, Gregory G.Lennon, Christal Douglas, Dean Nizetic, Peter N.Goodfellow1 and Hans Lehrach
Genome Analysis Laboratory and 'Molecular Human Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK and 2Department of Biochemistry, Li Shu Fan Building, Sassoon Road, University of Hong Kong, Hong Kong
Received March 12, 1991; Revised and Accepted May 16, 1991
', answer the user's query. |
What is the biomedical concept corresponding to 'yeast'? | [
"saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883)",
"saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (saccharomyces cerevisiae)",
"baker's yeast (saccharomyces cerevisiae)",
"mycoderma cerevisiae (saccharomyces cerevisiae)",
"brewer's yeast (saccharomyces ce... | [
"true yeasts (saccharomycotina)",
"saccharomyces cerevisiae or paradoxus (saccharomyces cf. cerevisiae/paradoxus)",
"saccharomyces lactis (kluyveromyces lactis)",
"saccharomyces albicans (candida albicans)"
] | Given the context 'ABSTRACT
A direct hybridization protocol is described for screening cosmid and yeast artificial chromosome libraries with pools of Alu-PCR products from somatic cell or irradiation hybrids.', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'A series of human X chromosome irradiation hybrids were mapped by this method, using a cosmid reference library for comparisons between overlapping hybrids to identify interesting clones for further analysis.
', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'INTRODUCTION
The generation of human DNA probes specific for individual chromosomes and subregions of chromosomes has been advanced with Alu-sequence primed polymerase chain reaction amplification (Alu-PCR, 1-3).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'This method specifically amplifies sequences between Alu repeats from human DNA in somatic cell hybrids and yeast artificial chromosomes (YACs, 4).', answer the user's query. |
What is the biomedical concept corresponding to 'yeast'? | [
"saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883)",
"saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (saccharomyces cerevisiae)",
"baker's yeast (saccharomyces cerevisiae)",
"mycoderma cerevisiae (saccharomyces cerevisiae)",
"brewer's yeast (saccharomyces ce... | [
"true yeasts (saccharomycotina)",
"saccharomyces cerevisiae or paradoxus (saccharomyces cf. cerevisiae/paradoxus)",
"saccharomyces lactis (kluyveromyces lactis)",
"saccharomyces albicans (candida albicans)"
] | Given the context 'This method specifically amplifies sequences between Alu repeats from human DNA in somatic cell hybrids and yeast artificial chromosomes (YACs, 4).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'Two new human specific Alu primers were used to generate DNA probes from a series of irradiation-reduced hybrids containing multiple human X chromosome fragments of 1-2000 kb on a hamster chromosome background (5; P.N.G., unpublished).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'Two new human specific Alu primers were used to generate DNA probes from a series of irradiation-reduced hybrids containing multiple human X chromosome fragments of 1-2000 kb on a hamster chromosome background (5; P.N.G., unpublished).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'The Alu-PCR products were hybridized as a pool of probes to X-specific cosmid and YAC libraries, after
competitive reassociation with an excess of human DNA to both the library filters and radioactively labelled Alu-PCR products.', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'METHODS
Two human Alu sequence primers were generated which were shown to be human specific; 3144 from the 3' end of Alu: 5'-GAGCGAGACTCCGTCTCAAA-3' and 2729 from the 5' end of Alu: 5'-GTGGATCACCTGAGGTCAGGAGTTC-3'.', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'METHODS
Two human Alu sequence primers were generated which were shown to be human specific; 3144 from the 3' end of Alu: 5'-GAGCGAGACTCCGTCTCAAA-3' and 2729 from the 5' end of Alu: 5'-GTGGATCACCTGAGGTCAGGAGTTC-3'.', answer the user's query. |
What is the biomedical concept corresponding to 'chinese hamster'? | [
"chinese hamster (cricetulus griseus)",
"chinese hamsters (cricetulus griseus)"
] | [
"common hamster (cricetus cricetus)",
"golden hamster (mesocricetus auratus)",
"syrian hamster (mesocricetus auratus)",
"syrian golden hamster (mesocricetus auratus)"
] | Given the context 'Chinese hamster DNA and no DNA PCR reactions were done to control for non-human products (data not shown).
', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'Chinese hamster DNA and no DNA PCR reactions were done to control for non-human products (data not shown).
', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'The radioactively labelled pool of fragments was prehybridized with 37.5 ,^g of total human DNA and 12.5 tsg of hamster DNA immobilized on a cellulose support matrix, prepared as previously described (7).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'I I
Figur 2a and 2b: Hybridization of Alu-PCR products generated with Alu primer 3144 from irradiation hybrid 48 to duplicate copies of 22 x22cm filters containing 9216 human X chromosome cosmids (8).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'Figure 1: A schematic diagram of the human X chromosome alongside the approximate cytogenetic location of fragments identified in nine irradiation hybrids (numbers across the top).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'The human X fragments were identified by hybridization of 27 known DNA markers (indicated by a black line; P.N.G, unpublished) or by cosmids in common with unique X chromosome probes in the reference library database (open boxes and Table 1).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'denatured and sheared total human DNA in 50% formamide, 4XSSC, 0.05 M sodium phosphate pH 7.2, 0.001 M EDTA, 10% dextran sulphate, 1.0% SDS, 50 isg/ml denatured salmon sperm DNA and OxDenhardt's solution.', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'The radioactively labelled Alu-PCR products were denatured and added to fresh
hybridization solution without human DNA competitor at 1 x 106
cpm/ml and hybridized at 42?C for 16 hours.', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'For each hybridization, two sets of duplicate cosmid filters were used from the ICRF reference library system (8), each containing 9216 flow-sorted human X chromosome cosmid clones or approximately 2 chromosome equivalents on a 22 x 22 cm filter (9).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'RESULTS
A panel of 195 X chromosome irradiation hybrids was constructed (50,000 rads) and characterized by DNA hybridization using 27 X chromosome markers and flourescence in situ hybridization using total human DNA as probe (Benham et al., 1989; P.N.G., unpublished).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'All nine hybrids were used in PCR reactions with 3'-Alu primer 3144 and two were used with 5'-Alu
Figure 3: Hybridization of Alu-PCR products generated with Alu primer 3144 from irradiation hybrid 54 to a filter containing 420 YAC clones from the human X chromosome.', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'Example hybridizations to a human X chromosome cosmid filter in Fig 2 shows the intensity and reliability of positive clones identified on duplicate filters with Alu-PCR products from the same irradiation hybrid (48) and the independence of clones identified with Alu-PCR products from a different hybrid (54).', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'Fig 3 shows a single positive YAC clone after hybridization of Alu-PCR products from irradiation hybrid 54 to a filter containing about 420 YAC clones specific for the human X chromosome.
', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'Since only 27 probes from the X chromosome were used to initially characterize the hybrids and the length of individual human fragments in the irradiation hybrids is about 1000-5000 kb, many regions could have been undetected in the original analysis.', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'However, since the exact length of the human DNA fragments for each hybrid and the spacing of Alu-PCR products along the chromosome is not known, it is difficult to directly correlate the number of target cosmids to the DNA content of the hybrids.
', answer the user's query. |
What is the biomedical concept corresponding to 'human'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"kingdom",
"genus"
] | Given the context 'The dissection of a total genomic YAC library by this method may be more efficient than generating chromosome specific YAC libraries from somatic cell hybrids (usually a haploid human chromosome on a diploid or greater rodent background) or flow-sorted chromosomes, because of the low transformation efficiency of yeast.
', answer the user's query. |
What is the biomedical concept corresponding to 'yeast'? | [
"saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883)",
"saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (saccharomyces cerevisiae)",
"baker's yeast (saccharomyces cerevisiae)",
"mycoderma cerevisiae (saccharomyces cerevisiae)",
"brewer's yeast (saccharomyces ce... | [
"true yeasts (saccharomycotina)",
"saccharomyces cerevisiae or paradoxus (saccharomyces cf. cerevisiae/paradoxus)",
"saccharomyces lactis (kluyveromyces lactis)",
"saccharomyces albicans (candida albicans)"
] | Given the context 'The dissection of a total genomic YAC library by this method may be more efficient than generating chromosome specific YAC libraries from somatic cell hybrids (usually a haploid human chromosome on a diploid or greater rodent background) or flow-sorted chromosomes, because of the low transformation efficiency of yeast.
', answer the user's query. |
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