query stringlengths 52 186 | positive listlengths 1 10 | negative listlengths 1 10 | system stringlengths 49 1.02k |
|---|---|---|---|
What is the biomedical concept corresponding to 'phenylmethylsulfonyl fluoride'? | [
"phenylmethylsulfonyl fluoride",
"fluoride, phenylmethylsulfonyl",
"benzenemethanesulfonyl fluoride",
"phenylmethanesulfonyl fluoride",
"fluoride, benzenemethanesulfonyl",
"fluoride, phenylmethanesulfonyl"
] | [
"p-toluenesulfonyl fluoride",
"para-toluenesulfonyl fluoride",
"phenylmethane sulfonyl fluoride",
"phenylmethylsulfonyl-trypsin",
"methanesulfonyl fluoride",
"benzenesulfonyl fluoride, 4-(2-aminoethyl)-",
"4-methylbenzenesulfonyl fluoride",
"4-toluenesulfonyl fluoride",
"sulfonyl fluoride",
"1-ben... | Given the context 'Total cellular protein was isolated using ice-cold lysis buffer (1× PBS, 10 mM phenylmethylsulfonyl fluoride (PMSF), 10 mM leupeptine, 10 mM aprotinin and 1% Triton X-100).', answer the user's query. |
What is the biomedical concept corresponding to 'pmsf'? | [
"phenylmethylsulfonyl fluoride",
"fluoride, phenylmethylsulfonyl",
"phenylmethanesulfonyl fluoride"
] | [
"4-pmsf",
"n-benzenesulfonyl-(s)-phenylalanine",
"phenylmethylsulfonyl-trypsin",
"n-(p-toluenesulfonyl)-(s)-phenylalanine",
"phenylmethane sulfonyl fluoride",
"n-(phenylsulfonyl)glycine",
"o,o-dimethyl s-(phenylmethyl) ester phosphorothioic acid",
"fluorobis(phenylsulfonyl)methane",
"1-fluoro-bis(ph... | Given the context 'Total cellular protein was isolated using ice-cold lysis buffer (1× PBS, 10 mM phenylmethylsulfonyl fluoride (PMSF), 10 mM leupeptine, 10 mM aprotinin and 1% Triton X-100).', answer the user's query. |
What is the biomedical concept corresponding to 'leupeptine'? | [
"leupeptin",
"leupeptin, (s)-isomer",
"leupeptin, monoacetate, (s)-isomer"
] | [
"leupeptins",
"cyla (leupeptin)",
"leupeptin acid",
"leupeptin acid, sulfate",
"beta-chloroalanyl-beta-chloroalanine",
"lysine suprofen",
"n-(2-carboxybenzoyl)leucine",
"beta-chloroalanine",
"lysinomethylalanine",
"l-lysine, 2-(4-chlorophenoxy)-2-methylpropanoate"
] | Given the context 'Total cellular protein was isolated using ice-cold lysis buffer (1× PBS, 10 mM phenylmethylsulfonyl fluoride (PMSF), 10 mM leupeptine, 10 mM aprotinin and 1% Triton X-100).', answer the user's query. |
What is the biomedical concept corresponding to 'triton x-100'? | [
"triton x-100",
"triton x 100",
"triton x100",
"triton x305",
"triton x 305",
"triton x-45",
"triton x45",
"triton x 45",
"triton x-305"
] | [
"triton a 20",
"triton x-114",
"triton n 101",
"triton df 16",
"triton n-101",
"triton x-165",
"triton-x-165",
"tx-100",
"triton df-16",
"tn detergent"
] | Given the context 'Total cellular protein was isolated using ice-cold lysis buffer (1× PBS, 10 mM phenylmethylsulfonyl fluoride (PMSF), 10 mM leupeptine, 10 mM aprotinin and 1% Triton X-100).', answer the user's query. |
What is the biomedical concept corresponding to 'sds'? | [
"sodium dodecyl sulfate",
"dodecyl sulfate, sodium",
"sulfate, sodium dodecyl"
] | [
"sdds",
"dhssp",
"dsgss",
"dasdss",
"sdtsb",
"dsahs",
"dsspd",
"ts-hds",
"sdval",
"hddsm"
] | Given the context 'Twenty-five micrograms of protein was loaded on 12% SDS–PAGE gel followed by transfer to nitrocellulose membrane PROTRAN (Perkin-Elmer Life Sciences, Boston, USA).', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Stimulation of cells with increasing concentrations of LPS (0–10 μg/ml) resulted in a dose–response accumulation of cytokines in the cell culture media of RAW 264.7-apoE3 and -apoE4 cells (Fig. 1).', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'In the cases of IL1β and MIP1α (Fig. 1A and B), there was a tendency for apoE4 expressing cells to secrete higher levels of cytokines at the majority of LPS concentrations tested, although the inter-group differences did not reach statistical significance (Fig.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'In contrast apoE4-macrophages produced 99%, 62%, 54%, and 83% more TNFα than E3 cells when stimulated at 0.1, 0.4, 0.8, and 10 μg/ml LPS (Fig. 1D).', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Furthermore, when IL10, an anti-inflammatory cytokine, was measured in the culture media, it was observed that apoE4-cells secreted lower concentrations of the cytokine, at all three LPS concentrations tested, with the differences reaching significance at the higher LPS concentrations (0.8 and 10 μg/... |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Furthermore, when IL10, an anti-inflammatory cytokine, was measured in the culture media, it was observed that apoE4-cells secreted lower concentrations of the cytokine, at all three LPS concentrations tested, with the differences reaching significance at the higher LPS concentrations (0.8 and 10 μg/... |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Following stimulation for 6 h at different LPS concentrations, NF-κB activity augmented in both cell lines.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'In apoE3 expressing macrophages, NF-κB activity increased ∼2.5-fold (P < 0.005) at a concentration of 0.01 μg/ml, with no further increase evident with increasing concentrations of LPS.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'In E4 cells, a higher activation of NF-κB (∼4.2-fold change, P < 0.005) was evident in cells stimulated with 0.01 μg/ml LPS, with a maximum ∼5-fold increase relative to apoE3 controls evident following stimulation with 0.1 μg/ml LPS (Fig.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'In E4 cells, a higher activation of NF-κB (∼4.2-fold change, P < 0.005) was evident in cells stimulated with 0.01 μg/ml LPS, with a maximum ∼5-fold increase relative to apoE3 controls evident following stimulation with 0.1 μg/ml LPS (Fig.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Comparable differences between genotypes on NF-κB activity were observed at 12 and 24 h, with a time-dependent accumulation of alkaline phosphatase in the cell culture media evident after LPS (0.1 μg/ml) stimulation, with 100%, 64%, and 48% differences between genotypes evident at 6, 12, and 24 h, re... |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Western blotting analysis showed higher HO-1 protein concentrations in apoE4 macrophages in both untreated (controls) and LPS (1 μg/ml) treated cells (Fig. 4B).', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'The gene expression profiles were consistent with protein levels, with control and LPS stimulated cells expressing apoE4, producing 235% and 180% higher HO-1 mRNA relative to apoE3-macrophages (Fig. 4A).', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'In addition, LPS, a Toll-like receptor 4 (TLR 4) ligand that triggers cytokine expression by activation of a signalling cascade, was applied to investigate innate immune response, given that it is a commonly used approach, and that TLR4 activation is regarded to be relevant in the pathogenesis of ath... |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Following LPS stimulation, higher mRNA levels of the pro-inflammatory cytokines TNFα and, IL1β, and the chemokine, MIP1α, with a trend towards lower levels of the anti-inflammatory cytokine IL10 were evident in the apoE4 cell line.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '[14] determined that apoE4 mice showed elevated systemic and brain pro-inflammatory cytokines following intravenous administration of LPS, and Ophir et al.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '[12] demonstrated that the expression of inflammation genes was higher and more prolongated in the brains of apoE4 following intracerebroventricular injection of LPS.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'NF-κB is a redox sensitive transcription factor, and therefore it was hypothesised that the increased oxidative stress observed in the apoE4 macrophages could contribute to a higher cytokine production by enhancing the activation of NF-κB. Here, we demonstrate through a reporter gene assay, that the ... |
What is the biomedical concept corresponding to 'biliverdin'? | [
"biliverdin",
"biliverdine",
"ix, biliverdin",
"biliverdin ix",
"alpha, biliverdin ix",
"ix alpha, biliverdin",
"biliverdin ix alpha"
] | [
"mesobiliverdin",
"mesobiliverdin ix",
"biliverdin xiiia",
"biliverdin xiiia dme",
"biliverdin ix beta dimethyl ester",
"biliverdin ix alpha dimethyl ester",
"biliverdin ix gamma dimethyl ester",
"(hydroxymethyl)bilane",
"biliverdin ix delta dimethyl ester",
"biliverdin xiiig"
] | Given the context 'HO-1 catalyses the rate limiting reaction in the degradation of heme, to yield biliverdin (with radical scavenging properties), carbon monoxide (a vascular modulator), and iron', answer the user's query. |
What is the biomedical concept corresponding to 'carbon monoxide'? | [
"carbon monoxide",
"monoxide, carbon",
"co (carbon monoxide)"
] | [
"nitrogen monoxide",
"monoxide, nitrogen",
"dioxide, carbon",
"carbon dioxide",
"carbon dioxide ion",
"carbon dioxide, mixt. with nitrogen and oxygen",
"dioxide, nitrogen",
"nitrogen dioxide",
"carbon suboxide",
"isoprene monoxide"
] | Given the context 'HO-1 catalyses the rate limiting reaction in the degradation of heme, to yield biliverdin (with radical scavenging properties), carbon monoxide (a vascular modulator), and iron', answer the user's query. |
What is the biomedical concept corresponding to 'iron'? | [
"iron"
] | [
"irone",
"iron, dietary",
"irones",
"dietary iron",
"iron(v)",
"mol-iron",
"iron(iv)",
"ferrous oxide",
"feg iron",
"ferrous compounds"
] | Given the context 'HO-1 catalyses the rate limiting reaction in the degradation of heme, to yield biliverdin (with radical scavenging properties), carbon monoxide (a vascular modulator), and iron', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'ApoE4-macrophages demonstrated increased levels of HO-1 under baseline conditions, and a stronger up-regulation of HO-1 at the mRNA and protein levels following LPS application.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Cytokine production in RAW 264.7-apoE3 and -apoE4 following stimulation with increasing concentrations of LPS (0–10 μg/ml) for 4 h. Supernatants were collected for ELISA analysis 20 h later.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '∗P < 0.05, ∗∗P < 0.01, comparing E3- vs. E4-cells at each LPS concentration.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'Cytokine mRNA levels measured using reverse transcription real-time PCR in RAW 264.7-apoE3 and -apoE4 following stimulation with LPS (1 μg/ml) for 6 h or 1 h (TNFα).', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, comparing E3- vs. E4-cells at each LPS concentration.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '(A) NF-κB activity detected with alkaline phosphatase reporter gene assay in RAW 264.7-apoE3 and -apoE4 following stimulation with increasing concentrations of LPS (0–1 μg/ml) for 6 h. (B) NF-κB activity following stimulation with LPS (0.1 μg/ml) for 6, 12, and 24 h. Results are calculated as chemilu... |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '(A) NF-κB activity detected with alkaline phosphatase reporter gene assay in RAW 264.7-apoE3 and -apoE4 following stimulation with increasing concentrations of LPS (0–1 μg/ml) for 6 h. (B) NF-κB activity following stimulation with LPS (0.1 μg/ml) for 6, 12, and 24 h. Results are calculated as chemilu... |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '∗P < 0.05, ∗∗P < 0. 01, ∗∗∗P < 0.001 comparing E3- vs. E4-cells at each LPS concentration; (C) control non-stimulated cells.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '(A) HO-1 mRNA levels detected with reverse transcription real-time PCR following stimulation with LPS (1 μg/ml) for 24 h. Results are calculated with the 2−ΔΔCt method and data is expressed as mean ± SEM of four independent experiments performed in duplicate.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context '∗P < 0.05, ∗∗∗P < 0.001, comparing E3- vs. E4-cells at each LPS concentration.', answer the user's query. |
What is the biomedical concept corresponding to 'lps'? | [
"lipopolysaccharides",
"lipopolysaccharide"
] | [
"lipopolysaccharide a",
"lipopolysaccharides, deacylated",
"lps-9",
"deacylated lipopolysaccharides",
"lps 9",
"lps receptor",
"lipopolysaccharide b",
"proteus lipopolysaccharide",
"lps-asd",
"endotoxin"
] | Given the context 'HO-1 levels as determined by Western blotting in relation to α-tubulin in RAW 264.7-apoE3 and -apoE4 under baseline conditions (control) and following stimulation with LPS (1 μg/ml) for 24 h.', answer the user's query. |
What is the biomedical concept corresponding to 'quaternary ammonium'? | [
"ammonium compounds, quaternary",
"ammonium compound, quaternary",
"quaternary ammonium compound",
"compound, quaternary ammonium",
"quaternary ammonium compounds"
] | [
"ammonium compounds",
"ammonium",
"quaternary bisammonium salt",
"ammonium compounds, trimethyl",
"trimethyl ammonium compounds",
"nh3 compound",
"chloride, ammonium",
"nitrogen compounds",
"hydroxide, ammonium",
"compounds, nitrogen"
] | Given the context 'Reduction of quaternary ammonium-induced ocular surface toxicity by emulsions: an in vivo study in rabbits', answer the user's query. |
What is the biomedical concept corresponding to 'quaternary ammonium compounds'? | [
"quaternary ammonium compounds",
"compound, quaternary ammonium",
"quaternary ammonium compound",
"ammonium compounds, quaternary",
"ammonium compound, quaternary"
] | [
"ammonium compounds",
"trimethyl ammonium compounds",
"nitrogen compounds",
"ammonium compounds, trimethyl",
"compounds, nitrogen",
"bis-trimethyl-ammonium compounds",
"quaternary bisammonium salt",
"bis trimethyl ammonium compounds",
"nh3 compound",
"benzyl ammonium compounds"
] | Given the context 'To evaluate and compare the toxicological profiles of two quaternary ammonium compounds (QAC), benzalkonium chloride (BAK), and cetalkonium chloride (CKC), in standard solution or cationic emulsion formulations in rabbit eyes using newly developed in vivo and ex vivo experimental approaches.', answer... |
What is the biomedical concept corresponding to 'benzalkonium chloride'? | [
"benzalkonium chloride",
"chloride, benzalkonium",
"benzalkonium",
"compounds, benzalkonium",
"benzalkonium compounds",
"alkyldimethylbenzylammonium chloride",
"chloride, alkyldimethylbenzylammonium"
] | [
"dimethylcocobenzalkonium chloride",
"cetalkonium chloride",
"benzethonium chloride",
"methylbenzethonium chloride",
"chloride, benzethonium",
"dibenzyldimethylammonium chloride",
"tyrothricin, benzalkonium chloride, benzocaine",
"(2-(n-benziloyl-n-methylamino)ethyl)diethylmethylammonium chloride",
... | Given the context 'To evaluate and compare the toxicological profiles of two quaternary ammonium compounds (QAC), benzalkonium chloride (BAK), and cetalkonium chloride (CKC), in standard solution or cationic emulsion formulations in rabbit eyes using newly developed in vivo and ex vivo experimental approaches.', answer... |
What is the biomedical concept corresponding to 'cetalkonium chloride'? | [
"cetalkonium chloride",
"cetyldimethylbenzylammonium chloride",
"benzyldimethyl-n-hexadecylammonium chloride"
] | [
"cetyltrimethylammonium chloride",
"cetrimonium chloride",
"cethyltrimethylammonium chloride",
"chloride, benzalkonium",
"benzalkonium chloride",
"dihexadecyldimethylammonium chloride",
"1-hexadecyltrimethylammonium chloride",
"hexadecyltrimethylammoniumchloride",
"methacryloxylethyl cetyl dimethyl ... | Given the context 'To evaluate and compare the toxicological profiles of two quaternary ammonium compounds (QAC), benzalkonium chloride (BAK), and cetalkonium chloride (CKC), in standard solution or cationic emulsion formulations in rabbit eyes using newly developed in vivo and ex vivo experimental approaches.', answer... |
What is the biomedical concept corresponding to 'dutp'? | [
"deoxy-utp",
"deoxyuridine triphosphate",
"2'-deoxyuridine 5'-triphosphate"
] | [
"imido-dutp",
"pyr-dutp",
"dump (2'-deoxyuridylic acid)",
"arginyl dutp",
"ru-dutp",
"5-propenyl-dutp",
"mt-dutp",
"n3rd-dutp",
"e-5-propenyl-dutp",
"2',3'-dideoxyuridine 5'-monophosphate"
] | Given the context 'Standard immunohistology in cryosections was also examined for cluster of differentiation (CD) 45+ infiltrating and terminal deoxynucleotidyl transferase-mediated dUTP-nick end labeling (TUNEL)+ apoptotic cells.', answer the user's query. |
What is the biomedical concept corresponding to 'quaternary ammonium'? | [
"ammonium compounds, quaternary",
"ammonium compound, quaternary",
"quaternary ammonium compound",
"compound, quaternary ammonium",
"quaternary ammonium compounds"
] | [
"ammonium compounds",
"ammonium",
"quaternary bisammonium salt",
"ammonium compounds, trimethyl",
"trimethyl ammonium compounds",
"nh3 compound",
"chloride, ammonium",
"nitrogen compounds",
"hydroxide, ammonium",
"compounds, nitrogen"
] | Given the context 'The acute administration of 15 instillations at 5 min intervals was a rapid and efficient model to assess quaternary ammonium toxicity profiles.', answer the user's query. |
What is the biomedical concept corresponding to 'oil'? | [
"oils"
] | [
"dietary oil",
"oil, dietary",
"dietary oils",
"plant oil",
"oils, dietary",
"vegetable oil",
"oil, plant",
"vegetable oils",
"plant oils",
"oil, vegetable"
] | Given the context 'During the past few years, several oil-in-water emulsions have been introduced on the market for the treatment of dry eye syndrome and are used as tear substitutes or vehicles for active compounds.', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'During the past few years, several oil-in-water emulsions have been introduced on the market for the treatment of dry eye syndrome and are used as tear substitutes or vehicles for active compounds.', answer the user's query. |
What is the biomedical concept corresponding to 'oil'? | [
"oils"
] | [
"dietary oil",
"oil, dietary",
"dietary oils",
"plant oil",
"oils, dietary",
"vegetable oil",
"oil, plant",
"vegetable oils",
"plant oils",
"oil, vegetable"
] | Given the context 'These oil-in-water emulsions can be visualized as tiny oil droplets suspended within an aqueous phase, and they are particularly suitable for dry eye syndromes because of the oil supplementation to the tear film.', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'These oil-in-water emulsions can be visualized as tiny oil droplets suspended within an aqueous phase, and they are particularly suitable for dry eye syndromes because of the oil supplementation to the tear film.', answer the user's query. |
What is the biomedical concept corresponding to 'oil'? | [
"oils"
] | [
"dietary oil",
"oil, dietary",
"dietary oils",
"plant oil",
"oils, dietary",
"vegetable oil",
"oil, plant",
"vegetable oils",
"plant oils",
"oil, vegetable"
] | Given the context 'These oil-in-water emulsions can be visualized as tiny oil droplets suspended within an aqueous phase, and they are particularly suitable for dry eye syndromes because of the oil supplementation to the tear film.', answer the user's query. |
What is the biomedical concept corresponding to 'oil'? | [
"oils"
] | [
"dietary oil",
"oil, dietary",
"dietary oils",
"plant oil",
"oils, dietary",
"vegetable oil",
"oil, plant",
"vegetable oils",
"plant oils",
"oil, vegetable"
] | Given the context 'These oil-in-water emulsions can be visualized as tiny oil droplets suspended within an aqueous phase, and they are particularly suitable for dry eye syndromes because of the oil supplementation to the tear film.', answer the user's query. |
What is the biomedical concept corresponding to 'oil'? | [
"oils"
] | [
"dietary oil",
"oil, dietary",
"dietary oils",
"plant oil",
"oils, dietary",
"vegetable oil",
"oil, plant",
"vegetable oils",
"plant oils",
"oil, vegetable"
] | Given the context 'Oil-in-water emulsions can be charged positively (for example, the surface of the tiny droplets becomes cationic) by adding quaternary ammonium compounds (QACs) as cationic agents.', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'Oil-in-water emulsions can be charged positively (for example, the surface of the tiny droplets becomes cationic) by adding quaternary ammonium compounds (QACs) as cationic agents.', answer the user's query. |
What is the biomedical concept corresponding to 'quaternary ammonium compounds'? | [
"quaternary ammonium compounds",
"compound, quaternary ammonium",
"quaternary ammonium compound",
"ammonium compounds, quaternary",
"ammonium compound, quaternary"
] | [
"ammonium compounds",
"trimethyl ammonium compounds",
"nitrogen compounds",
"ammonium compounds, trimethyl",
"compounds, nitrogen",
"bis-trimethyl-ammonium compounds",
"quaternary bisammonium salt",
"bis trimethyl ammonium compounds",
"nh3 compound",
"benzyl ammonium compounds"
] | Given the context 'Oil-in-water emulsions can be charged positively (for example, the surface of the tiny droplets becomes cationic) by adding quaternary ammonium compounds (QACs) as cationic agents.', answer the user's query. |
What is the biomedical concept corresponding to 'benzalkonium chloride'? | [
"benzalkonium chloride",
"chloride, benzalkonium",
"benzalkonium",
"compounds, benzalkonium",
"benzalkonium compounds",
"alkyldimethylbenzylammonium chloride",
"chloride, alkyldimethylbenzylammonium"
] | [
"dimethylcocobenzalkonium chloride",
"cetalkonium chloride",
"benzethonium chloride",
"methylbenzethonium chloride",
"chloride, benzethonium",
"dibenzyldimethylammonium chloride",
"tyrothricin, benzalkonium chloride, benzocaine",
"(2-(n-benziloyl-n-methylamino)ethyl)diethylmethylammonium chloride",
... | Given the context 'As the most commonly used preservative, benzalkonium chloride (BAK), has shown its high level of toxicity in vitro and ex vivo by stimulating epithelial cell death, acting as pro-inflammatory or pro-apoptotic mediators, inducing oxidative stress, and significantly altering the precorneal mucins.', an... |
What is the biomedical concept corresponding to 'oil'? | [
"oils"
] | [
"dietary oil",
"oil, dietary",
"dietary oils",
"plant oil",
"oils, dietary",
"vegetable oil",
"oil, plant",
"vegetable oils",
"plant oils",
"oil, vegetable"
] | Given the context 'Indeed, several papers have reported that the efficacy of different preservatives including BAK is attenuated when incorporated within an oil-in-water emulsion.', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'Indeed, several papers have reported that the efficacy of different preservatives including BAK is attenuated when incorporated within an oil-in-water emulsion.', answer the user's query. |
What is the biomedical concept corresponding to 'alkylbenzyldimethyl ammonium chlorides'? | [
"alkyldimethylbenzylammonium chloride",
"chloride, alkyldimethylbenzylammonium"
] | [
"quaternary ammonium compounds, benzylcoco alkyldimethyl, chlorides",
"quaternary ammonium compounds, benzyl-c10-18-alkyldimethyl, chlorides",
"benzyl((dodecylcarbamoyl)methyl)dimethylammonium chloride",
"dodecyldimethylbenzylammonium chloride",
"diallyldimethylammonium chloride",
"cetyldimethylbenzylammo... | Given the context 'BAK is composed of a mixture of alkylbenzyldimethyl ammonium chlorides bearing various alkyl chain lengths, each one with a different water solubility and water-octanol partition coefficient.', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'BAK is composed of a mixture of alkylbenzyldimethyl ammonium chlorides bearing various alkyl chain lengths, each one with a different water solubility and water-octanol partition coefficient.', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'BAK is composed of a mixture of alkylbenzyldimethyl ammonium chlorides bearing various alkyl chain lengths, each one with a different water solubility and water-octanol partition coefficient.', answer the user's query. |
What is the biomedical concept corresponding to 'octanol'? | [
"octanols",
"alcohols, octyl",
"octyl alcohols"
] | [
"n octanol",
"n-octanol",
"1 octanol",
"alcohol, n-octyl",
"1-octanol",
"2-octanol",
"n-octyl alcohol",
"n octyl alcohol",
"2-octanol, (r)-isomer",
"octoxynol"
] | Given the context 'BAK is composed of a mixture of alkylbenzyldimethyl ammonium chlorides bearing various alkyl chain lengths, each one with a different water solubility and water-octanol partition coefficient.', answer the user's query. |
What is the biomedical concept corresponding to 'cetalkonium chloride'? | [
"cetalkonium chloride",
"cetyldimethylbenzylammonium chloride",
"benzyldimethyl-n-hexadecylammonium chloride"
] | [
"cetyltrimethylammonium chloride",
"cetrimonium chloride",
"cethyltrimethylammonium chloride",
"chloride, benzalkonium",
"benzalkonium chloride",
"dihexadecyldimethylammonium chloride",
"1-hexadecyltrimethylammonium chloride",
"hexadecyltrimethylammoniumchloride",
"methacryloxylethyl cetyl dimethyl ... | Given the context 'We suggested the use of lipophilic cetalkonium chloride (CKC), one of the longest alkyl-chain BAK components, as a cationic agent in ophthalmic emulsions.', answer the user's query. |
What is the biomedical concept corresponding to 'ketamine'? | [
"ketamine",
"ketamine hydrochloride",
"ketalar",
"ketaset",
"cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)-",
"2-(2-chlorophenyl)-2-(methylamino)cyclohexanone",
"ketanest"
] | [
"(-)-ketamine",
"l-ketamine",
"s-ketamine",
"ketesse",
"deschloro-n-ethyl-ketamine",
"ketenimine",
"(s)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone",
"ketac cem",
"ketaset plus",
"ketac-glaze"
] | Given the context 'A mixture of ketamine (35 mg/kg; Imalgène 500; Merial, Lyon, France) and xylazine (5 mg/kg; Bayer, Puteaux, France) was used to anesthetize the animals.', answer the user's query. |
What is the biomedical concept corresponding to 'xylazine'? | [
"xylazine",
"xylazine hydrochloride",
"xylazine monohydrochloride",
"xylazine phosphate (1:1)",
"xylazin",
"xylaxine"
] | [
"xylinan",
"xylure",
"xylamine",
"xylamit",
"xylazole",
"xyloneural",
"xylocitin",
"xylamon",
"xylon",
"2,6-xylidine hydrochloride"
] | Given the context 'A mixture of ketamine (35 mg/kg; Imalgène 500; Merial, Lyon, France) and xylazine (5 mg/kg; Bayer, Puteaux, France) was used to anesthetize the animals.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclosporine a'? | [
"cyclosporine a",
"cyclosporine",
"cyclosporin a",
"cyclosporin",
"ciclosporin"
] | [
"cyclosporines",
"cyclosporine h",
"cyclosporine g",
"cyclosporine a acetate",
"cyclosporin c",
"cyclosporins",
"cyclosporin f",
"cyclosporin h",
"cyclosporin d",
"cyclosporin a, 2-(o-(2-hydroxyethyl)-d-serine)-"
] | Given the context 'We compared 0.02% BAK to 0.002% CKC since these two QAC concentrations confer equivalent positive charge to the emulsion surface (zeta potential around 20 mV), and similarly enhanced ocular delivery could be obtained with cyclosporine A (CsA)-emulsions containing 0.002% CKC or 0.02% BAK (data not sho... |
What is the biomedical concept corresponding to 'csa'? | [
"cyclosporine a",
"cyclosporine",
"cyclosporin a",
"cyclosporin",
"csa neoral",
"csa-neoral",
"ciclosporin"
] | [
"cyclosporines",
"cyclosporins",
"csh cyclosporin",
"cyclosporin c",
"cyclosporin f",
"cyclosporin a, 2-(o-(2-hydroxyethyl)-d-serine)-",
"meala-csa",
"cyclosporin h",
"cyclosporin g",
"cyclosporin o"
] | Given the context 'We compared 0.02% BAK to 0.002% CKC since these two QAC concentrations confer equivalent positive charge to the emulsion surface (zeta potential around 20 mV), and similarly enhanced ocular delivery could be obtained with cyclosporine A (CsA)-emulsions containing 0.002% CKC or 0.02% BAK (data not sho... |
What is the biomedical concept corresponding to 'paraformaldehyde'? | [
"paraformaldehyde",
"paraform"
] | [
"formalin",
"formaldehyde",
"formaldehydeaminal",
"formaldehyde, mixt. with ethanol",
"formaldehydesulfoxylate",
"oxyfluoride",
"fluoroform",
"formaldehyde hydrazone",
"2,2,2-trifluoroethyl formate",
"formaldehyde bisulfite"
] | Given the context 'Two nitrocellulose membranes (Millipore, Bedford, MA) were applied to the superior bulbar conjunctiva and then dipped into tubes containing 1.5 ml of cold PBS with 4% paraformaldehyde (PFA) for future cresyl violet cytology, and two Supor®-membrane (Gelman Sciences, Ann Arbor, MI) were dipped immedia... |
What is the biomedical concept corresponding to 'cresyl violet'? | [
"cresyl violet",
"cresyl violet, monoperchlorate",
"cresyl violet, mononitrate",
"cresyl violet nitrate",
"cresyl violet acetate"
] | [
"cresyl fast violet",
"methyl violet",
"violet, methyl",
"dyecycle violet",
"methylene violet",
"blue patent violet",
"pyrocatechol violet",
"patent blue violet",
"c.i. basic violet 2 monohydrochloride",
"fast red violet"
] | Given the context 'Two nitrocellulose membranes (Millipore, Bedford, MA) were applied to the superior bulbar conjunctiva and then dipped into tubes containing 1.5 ml of cold PBS with 4% paraformaldehyde (PFA) for future cresyl violet cytology, and two Supor®-membrane (Gelman Sciences, Ann Arbor, MI) were dipped immedia... |
What is the biomedical concept corresponding to 'cresyl violet'? | [
"cresyl violet",
"cresyl violet, monoperchlorate",
"cresyl violet, mononitrate",
"cresyl violet nitrate",
"cresyl violet acetate"
] | [
"cresyl fast violet",
"methyl violet",
"violet, methyl",
"dyecycle violet",
"methylene violet",
"blue patent violet",
"pyrocatechol violet",
"patent blue violet",
"c.i. basic violet 2 monohydrochloride",
"fast red violet"
] | Given the context 'Cresyl violet staining of conjunctival impression cytology and morphological evaluation', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'The membranes dipped in 4% PFA were washed in distilled water, dehydrated into ethanol, and stained by cresyl violet solution (1%, number 5235, Merck, Fontenay-sous-Bois, France) for 30 min.', answer the user's query. |
What is the biomedical concept corresponding to 'ethanol'? | [
"ethanol",
"ethyl alcohol",
"alcohol, grain",
"alcohol, ethyl",
"absolute alcohol",
"grain alcohol",
"alcohol, absolute"
] | [
"alcohols",
"elf alcohol",
"alcohol, sugar",
"sugar alcohol",
"fatty alcohol",
"alcohol, fatty",
"ethanol, ion(1-)",
"alcohol, wood",
"alcohol, rubbing",
"wood alcohol"
] | Given the context 'The membranes dipped in 4% PFA were washed in distilled water, dehydrated into ethanol, and stained by cresyl violet solution (1%, number 5235, Merck, Fontenay-sous-Bois, France) for 30 min.', answer the user's query. |
What is the biomedical concept corresponding to 'cresyl violet'? | [
"cresyl violet",
"cresyl violet, monoperchlorate",
"cresyl violet, mononitrate",
"cresyl violet nitrate",
"cresyl violet acetate"
] | [
"cresyl fast violet",
"methyl violet",
"violet, methyl",
"dyecycle violet",
"methylene violet",
"blue patent violet",
"pyrocatechol violet",
"patent blue violet",
"c.i. basic violet 2 monohydrochloride",
"fast red violet"
] | Given the context 'The membranes dipped in 4% PFA were washed in distilled water, dehydrated into ethanol, and stained by cresyl violet solution (1%, number 5235, Merck, Fontenay-sous-Bois, France) for 30 min.', answer the user's query. |
What is the biomedical concept corresponding to 'propidium iodide'? | [
"propidium iodide",
"iodide, propidium",
"propidium diiodide",
"diiodide, propidium",
"propidium"
] | [
"propidium monoazide",
"monoazido-propidium",
"diazido-propidium",
"pima (potassium iodide)",
"phosphon iodide",
"3-iodopropyltris(4-dimethylaminophenyl)phosphonium iodide",
"phospholine iodide",
"prolonium iodide",
"laurylpyridinium iodide",
"platinous iodide"
] | Given the context 'Soon after the FCM analysis, we stained the cell suspension with propidium iodide (PI 0.5 µg/ml; Sigma Chemical Company, St. Louis, MO).', answer the user's query. |
What is the biomedical concept corresponding to 'pentobarbital'? | [
"pentobarbital",
"pentobarbital sodium",
"monosodium salt pentobarbital",
"pentobarbitone",
"pentobarbital, monosodium salt",
"nembutal"
] | [
"1-(beta-d-glucopyranosyl)pentobarbital",
"1-(glucopyranosyl)pentobarbital, (s-(r*,r*))-isomer",
"1-(glucopyranosyl)pentobarbital, (r-(r*,s*))-isomer",
"1-(glucopyranosyl)pentobarbital, (r-(r*,r*))-isomer",
"methobarbitone",
"1-glu-pentobarbital",
"secbutobarbitone",
"novamobarb",
"1-(glucopyranosyl... | Given the context 'Two rabbits in each group were euthanized with a lethal dose of pentobarbital at D1.', answer the user's query. |
What is the biomedical concept corresponding to 'dutp'? | [
"deoxy-utp",
"deoxyuridine triphosphate",
"2'-deoxyuridine 5'-triphosphate"
] | [
"imido-dutp",
"pyr-dutp",
"dump (2'-deoxyuridylic acid)",
"arginyl dutp",
"ru-dutp",
"5-propenyl-dutp",
"mt-dutp",
"n3rd-dutp",
"e-5-propenyl-dutp",
"2',3'-dideoxyuridine 5'-monophosphate"
] | Given the context 'To detect apoptotic cells, a terminal deoxynucleotidyl transferase-mediated dUTP-nick end labeling (TUNEL) assay (Roche Diagnostics, Meylan, France) was used.', answer the user's query. |
What is the biomedical concept corresponding to 'cresyl violet'? | [
"cresyl violet",
"cresyl violet, monoperchlorate",
"cresyl violet, mononitrate",
"cresyl violet nitrate",
"cresyl violet acetate"
] | [
"cresyl fast violet",
"methyl violet",
"violet, methyl",
"dyecycle violet",
"methylene violet",
"blue patent violet",
"pyrocatechol violet",
"patent blue violet",
"c.i. basic violet 2 monohydrochloride",
"fast red violet"
] | Given the context 'Conjunctival impression cytology stained by cresyl violet at D1.', answer the user's query. |
What is the biomedical concept corresponding to 'cresyl violet'? | [
"cresyl violet",
"cresyl violet, monoperchlorate",
"cresyl violet, mononitrate",
"cresyl violet nitrate",
"cresyl violet acetate"
] | [
"cresyl fast violet",
"methyl violet",
"violet, methyl",
"dyecycle violet",
"methylene violet",
"blue patent violet",
"pyrocatechol violet",
"patent blue violet",
"c.i. basic violet 2 monohydrochloride",
"fast red violet"
] | Given the context 'The lesions observed in conjunctival IC after cresyl violet staining are summarized in Table 2.', answer the user's query. |
What is the biomedical concept corresponding to 'cresyl violet'? | [
"cresyl violet",
"cresyl violet, monoperchlorate",
"cresyl violet, mononitrate",
"cresyl violet nitrate",
"cresyl violet acetate"
] | [
"cresyl fast violet",
"methyl violet",
"violet, methyl",
"dyecycle violet",
"methylene violet",
"blue patent violet",
"pyrocatechol violet",
"patent blue violet",
"c.i. basic violet 2 monohydrochloride",
"fast red violet"
] | Given the context 'Description of cresyl violet conjunctival impression cytology results at D1 following repeated applications of quaternary ammonium compound emulsions and solutions', answer the user's query. |
What is the biomedical concept corresponding to 'quaternary ammonium compound'? | [
"quaternary ammonium compound",
"compound, quaternary ammonium",
"quaternary ammonium compounds",
"ammonium compound, quaternary",
"ammonium compounds, quaternary"
] | [
"ammonium compounds",
"trimethyl ammonium compounds",
"quaternary bisammonium salt",
"ammonium compounds, trimethyl",
"nitrogen compounds",
"bis-trimethyl-ammonium compounds",
"compounds, nitrogen",
"bis trimethyl ammonium compounds",
"quinolinium compounds",
"nh3 compound"
] | Given the context 'Description of cresyl violet conjunctival impression cytology results at D1 following repeated applications of quaternary ammonium compound emulsions and solutions', answer the user's query. |
What is the biomedical concept corresponding to 'propidium iodide'? | [
"propidium iodide",
"iodide, propidium",
"propidium diiodide",
"diiodide, propidium",
"propidium"
] | [
"propidium monoazide",
"monoazido-propidium",
"diazido-propidium",
"pima (potassium iodide)",
"phosphon iodide",
"3-iodopropyltris(4-dimethylaminophenyl)phosphonium iodide",
"phospholine iodide",
"prolonium iodide",
"laurylpyridinium iodide",
"platinous iodide"
] | Given the context 'Positive cells for RLA-DR (green, B) and TNFR1 (green, D) were viewed after propidium iodide staining (red) and cytospin centrifugation.', answer the user's query. |
What is the biomedical concept corresponding to 'dutp'? | [
"deoxy-utp",
"deoxyuridine triphosphate",
"2'-deoxyuridine 5'-triphosphate"
] | [
"imido-dutp",
"pyr-dutp",
"dump (2'-deoxyuridylic acid)",
"arginyl dutp",
"ru-dutp",
"5-propenyl-dutp",
"mt-dutp",
"n3rd-dutp",
"e-5-propenyl-dutp",
"2',3'-dideoxyuridine 5'-monophosphate"
] | Given the context 'Immunostaining of CD45 and terminal deoxynucleotidyl transferase-mediated dUTP-nick end labeling markers in cryosections', answer the user's query. |
What is the biomedical concept corresponding to 'propidium iodide'? | [
"propidium iodide",
"iodide, propidium",
"propidium diiodide",
"diiodide, propidium",
"propidium"
] | [
"propidium monoazide",
"monoazido-propidium",
"diazido-propidium",
"pima (potassium iodide)",
"phosphon iodide",
"3-iodopropyltris(4-dimethylaminophenyl)phosphonium iodide",
"phospholine iodide",
"prolonium iodide",
"laurylpyridinium iodide",
"platinous iodide"
] | Given the context 'Nuclei were stained in red with propidium iodide.', answer the user's query. |
What is the biomedical concept corresponding to 'amphotericin b'? | [
"amphotericin b",
"amphotericin"
] | [
"amphotericin a",
"n-methyl-d-glucamine amphotericin b",
"amphotericin b aglycone",
"amphotericin b, n-(((3-(dimethylamino)propyl)amino)(ethylamino)methylene)-",
"amphotericin b, 5,8,9-trideoxy-7,10-dihydroxy-5-oxo-",
"amphotericin b methyl ester",
"amphotericin b, compd. with 1-deoxy-1-(methylamino)-d-... | Given the context 'Amphotericin B emulsion was found to be better tolerated than the commercial solution of Fungizone® in rabbits.', answer the user's query. |
What is the biomedical concept corresponding to 'fungizone'? | [
"fungizone",
"amphotericin"
] | [
"fungistat",
"fungiqual",
"fungitrol",
"fungifos",
"fungicidin",
"fungimycin",
"fungichromin",
"fungerin",
"mycilan",
"mycospor"
] | Given the context 'Amphotericin B emulsion was found to be better tolerated than the commercial solution of Fungizone® in rabbits.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclosporine'? | [
"cyclosporine",
"cyclosporine a",
"cyclosporin",
"cyclosporin a",
"ciclosporin"
] | [
"cyclosporines",
"cyclosporine h",
"cyclosporine g",
"cyclosporins",
"cyclosporin c",
"csh cyclosporin",
"cyclosporin f",
"cyclosporin o",
"cyclosporin h",
"cyclosporin-like substance"
] | Given the context 'Several clinical studies of emulsion-based eye drops of artificial tears or cyclosporine showed good overall safety, efficacy, and comfort in normal subjects and dry eye patients.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclosporine a'? | [
"cyclosporine a",
"cyclosporine",
"cyclosporin a",
"cyclosporin",
"ciclosporin"
] | [
"cyclosporines",
"cyclosporine h",
"cyclosporine g",
"cyclosporine a acetate",
"cyclosporin c",
"cyclosporins",
"cyclosporin f",
"cyclosporin h",
"cyclosporin d",
"cyclosporin a, 2-(o-(2-hydroxyethyl)-d-serine)-"
] | Given the context 'Formulation of cyclosporine A in a cationic emulsion results in significantly improved (11 fold) corneal and conjunctival delivery in rabbits compared to olive oil.', answer the user's query. |
What is the biomedical concept corresponding to 'indomethacin'? | [
"indomethacin",
"indometacin",
"indomethacin hydrochloride",
"1h-indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-",
"indocin",
"indocid"
] | [
"indomethacin-im",
"indomethacin imidazole",
"no-indomethacin",
"indomethacin carboxymethyl ester",
"indomethacin ethyl ester",
"indomethacin morpholinylamide",
"1h-indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-(dimethylamino)-2-methyl-",
"indomethacin triethylene ester",
"(des-4-chlorobenzoyl)indomet... | Given the context 'Compared with the anionic emulsion, indomethacin in cationic emulsion provided significantly higher drug levels in the aqueous humor and sclera or retina, and submicron cationic lipid emulsion enhanced the ocular bioavailability of cyclosporine A.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclosporine a'? | [
"cyclosporine a",
"cyclosporine",
"cyclosporin a",
"cyclosporin",
"ciclosporin"
] | [
"cyclosporines",
"cyclosporine h",
"cyclosporine g",
"cyclosporine a acetate",
"cyclosporin c",
"cyclosporins",
"cyclosporin f",
"cyclosporin h",
"cyclosporin d",
"cyclosporin a, 2-(o-(2-hydroxyethyl)-d-serine)-"
] | Given the context 'Compared with the anionic emulsion, indomethacin in cationic emulsion provided significantly higher drug levels in the aqueous humor and sclera or retina, and submicron cationic lipid emulsion enhanced the ocular bioavailability of cyclosporine A.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclosporine'? | [
"cyclosporine",
"cyclosporine a",
"cyclosporin",
"cyclosporin a",
"ciclosporin"
] | [
"cyclosporines",
"cyclosporine h",
"cyclosporine g",
"cyclosporins",
"cyclosporin c",
"csh cyclosporin",
"cyclosporin f",
"cyclosporin o",
"cyclosporin h",
"cyclosporin-like substance"
] | Given the context 'BAK cationic emulsion of cyclosporine significantly improved the penetration of cyclosporine over a negatively charged emulsion.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclosporine'? | [
"cyclosporine",
"cyclosporine a",
"cyclosporin",
"cyclosporin a",
"ciclosporin"
] | [
"cyclosporines",
"cyclosporine h",
"cyclosporine g",
"cyclosporins",
"cyclosporin c",
"csh cyclosporin",
"cyclosporin f",
"cyclosporin o",
"cyclosporin h",
"cyclosporin-like substance"
] | Given the context 'BAK cationic emulsion of cyclosporine significantly improved the penetration of cyclosporine over a negatively charged emulsion.', answer the user's query. |
What is the biomedical concept corresponding to 'quaternary ammonium compounds'? | [
"quaternary ammonium compounds",
"compound, quaternary ammonium",
"quaternary ammonium compound",
"ammonium compounds, quaternary",
"ammonium compound, quaternary"
] | [
"ammonium compounds",
"trimethyl ammonium compounds",
"nitrogen compounds",
"ammonium compounds, trimethyl",
"compounds, nitrogen",
"bis-trimethyl-ammonium compounds",
"quaternary bisammonium salt",
"bis trimethyl ammonium compounds",
"nh3 compound",
"benzyl ammonium compounds"
] | Given the context 'A high level infiltration of CD45+ inflammatory cells and TUNEL+ apoptotic cells was found in the limbus and conjunctiva, especially in quaternary ammonium compounds solution-receiving eyes compared to quaternary ammonium compounds emulsion-instilled eyes.', answer the user's query. |
What is the biomedical concept corresponding to 'quaternary ammonium compounds'? | [
"quaternary ammonium compounds",
"compound, quaternary ammonium",
"quaternary ammonium compound",
"ammonium compounds, quaternary",
"ammonium compound, quaternary"
] | [
"ammonium compounds",
"trimethyl ammonium compounds",
"nitrogen compounds",
"ammonium compounds, trimethyl",
"compounds, nitrogen",
"bis-trimethyl-ammonium compounds",
"quaternary bisammonium salt",
"bis trimethyl ammonium compounds",
"nh3 compound",
"benzyl ammonium compounds"
] | Given the context 'A high level infiltration of CD45+ inflammatory cells and TUNEL+ apoptotic cells was found in the limbus and conjunctiva, especially in quaternary ammonium compounds solution-receiving eyes compared to quaternary ammonium compounds emulsion-instilled eyes.', answer the user's query. |
What is the biomedical concept corresponding to 'octanol'? | [
"octanols",
"alcohols, octyl",
"octyl alcohols"
] | [
"n octanol",
"n-octanol",
"1 octanol",
"alcohol, n-octyl",
"1-octanol",
"2-octanol",
"n-octyl alcohol",
"n octyl alcohol",
"2-octanol, (r)-isomer",
"octoxynol"
] | Given the context 'The lipophilicity of CKC partition is almost 100-fold more important in octanol than in water, which is four to five times higher than BAK.', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'The lipophilicity of CKC partition is almost 100-fold more important in octanol than in water, which is four to five times higher than BAK.', answer the user's query. |
What is the biomedical concept corresponding to 'water'? | [
"water",
"hydrogen oxide"
] | [
"water, mineral",
"mineral water",
"water, drinking",
"drinking water",
"mineral waters",
"water, heavy",
"waters, mineral",
"water, bottled",
"vapor, water",
"carbonated water"
] | Given the context 'Compared to BAK, CKC distributed even more preferentially into the oil phase (allowing reduced cationic agent content) with a lesser amount dissolved in the water phase and free for possible toxic damage.', answer the user's query. |
What is the biomedical concept corresponding to 'oligosaccharide'? | [
"oligosaccharide",
"oligosaccharides"
] | [
"glycan",
"disaccharide",
"glycans",
"lipid-linked oligosaccharides",
"disaccharides",
"phospho-oligosaccharide",
"monosaccharide",
"polysaccharopeptide",
"polysaccharide",
"branched-chain oligosaccharides"
] | Given the context 'This study investigated the influence of integrin expression as well as the oligosaccharide structure of surface N-glycoproteins on cell behavior of two primary uveal (92–1 and Mel202) and two primary cutaneous (FM55P and IGR-39) melanoma cell lines.', answer the user's query. |
What is the biomedical concept corresponding to 'β1–6 branched n-oligosaccharides'? | [
"oligosaccharides"
] | [
"branched-chain oligosaccharides",
"oligosaccharides, branched-chain",
"glcnac branched hexasaccharide",
"beta-glycan",
"poly-beta-(1,6)-n-acetylglucosamine",
"man6glcnac2",
"beta-n-acetylglucosamine",
"beta n acetylglucosamine",
"desialylated oligosaccharides",
"n-acetylglucosamine trimer"
] | Given the context 'Cell surface β1–6 branched N-oligosaccharides were measured by their specific binding to PHA-L followed by flow cytometry, and the fibronectin receptors bearing β1–6 GlcNAc branched N-linked glycans were identified.', answer the user's query. |
What is the biomedical concept corresponding to 'β1–6 glcnac'? | [
"beta-n-acetylglucosamine",
"beta n acetylglucosamine"
] | [
"glcnac-1-6-glcnac",
"galnac-1-6-glcnac",
"glcnacbeta1-6galnac",
"glcnacbeta1-4-glcnac",
"galactofuranosyl-1-6-n-acetylglucosamine",
"man6glcnac2",
"beta-galactose(1-6)-n-acetylgalactosamine",
"(glcnac)2",
"(glcnac)7",
"n-acetylglucosaminyl beta(1-6)n-acetylgalactosamine"
] | Given the context 'Cell surface β1–6 branched N-oligosaccharides were measured by their specific binding to PHA-L followed by flow cytometry, and the fibronectin receptors bearing β1–6 GlcNAc branched N-linked glycans were identified.', answer the user's query. |
What is the biomedical concept corresponding to 'n-linked glycans'? | [
"glycans",
"glycan"
] | [
"beta-n-acetylglucosamine",
"n-acetylglucosamine",
"n acetylglucosamine",
"beta n acetylglucosamine",
"di-n-acetylglucosamine",
"n acetyl d galactosamine",
"poly-n-acetylglucosamine",
"beta-glycan",
"n-acetyllactosamine",
"n-acetylmannosamine"
] | Given the context 'Cell surface β1–6 branched N-oligosaccharides were measured by their specific binding to PHA-L followed by flow cytometry, and the fibronectin receptors bearing β1–6 GlcNAc branched N-linked glycans were identified.', answer the user's query. |
What is the biomedical concept corresponding to 'n-acetylglucosamine'? | [
"n-acetylglucosamine",
"n acetylglucosamine",
"acetylglucosamine",
"beta-n-acetylglucosamine",
"n acetyl glucosamine",
"n-acetyl glucosamine",
"n-acetyl-d-glucosamine",
"beta n acetylglucosamine",
"n acetyl d glucosamine",
"n-acetyl-beta-d-glucosamine"
] | [
"n-acetyllactosamine",
"n-acetyltalosamine",
"n-acetyl-d-galactosamine",
"n acetyl d galactosamine",
"1-deoxy-n-acetylglucosamine",
"n-acetylmannosamine",
"n-acetylsucrosamine",
"n-acetyl-d-mannosamine"
] | Given the context 'In addition, the transcript of GnT-V (the enzyme that catalyzes the addition of N-acetylglucosamine to the core mannose of di- and tri-antennary N-glycans through a β1–6 linkage) was analyzed by semiquantitative RT–PCR.', answer the user's query. |
What is the biomedical concept corresponding to 'mannose'? | [
"mannose",
"d-mannose",
"d mannose",
"mannopyranose",
"mannopyranoside"
] | [
"alpha-methyl-d-mannose",
"mannosamine",
"mannose-mannose-mannose",
"mannosamine, (d)-isomer",
"mannoside",
"d-mannosamine",
"4-o-(beta-d-mannopyranosyl)-d-mannose",
"mannan",
"penta-b-alpha-d-mannopyranose",
"mannosides"
] | Given the context 'In addition, the transcript of GnT-V (the enzyme that catalyzes the addition of N-acetylglucosamine to the core mannose of di- and tri-antennary N-glycans through a β1–6 linkage) was analyzed by semiquantitative RT–PCR.', answer the user's query. |
What is the biomedical concept corresponding to 'n-glycans'? | [
"glycans",
"glycan"
] | [
"n-acetylglucosamine",
"n acetylglucosamine",
"beta-n-acetylglucosamine",
"beta n acetylglucosamine",
"poly-n-acetylglucosamine",
"n-acetylmannosamine",
"n-acetyllactosamine",
"n acetyl d galactosamine",
"n-acetylsucrosamine",
"di-n-acetylglucosamine"
] | Given the context 'In addition, the transcript of GnT-V (the enzyme that catalyzes the addition of N-acetylglucosamine to the core mannose of di- and tri-antennary N-glycans through a β1–6 linkage) was analyzed by semiquantitative RT–PCR.', answer the user's query. |
What is the biomedical concept corresponding to 'β1–6 branched n-oligosaccharides'? | [
"oligosaccharides"
] | [
"branched-chain oligosaccharides",
"oligosaccharides, branched-chain",
"glcnac branched hexasaccharide",
"beta-glycan",
"poly-beta-(1,6)-n-acetylglucosamine",
"man6glcnac2",
"beta-n-acetylglucosamine",
"beta n acetylglucosamine",
"desialylated oligosaccharides",
"n-acetylglucosamine trimer"
] | Given the context 'Semiquantitative RT–PCR analysis showed that the tested cells did not differ in mRNA levels of β1–6 –N-acetylglucosaminyltransferase V. However, FACS analysis showed that 92–1, Mel202 and IGR-39 cells expressed significantly higher amounts of β1–6 branched N-oligosaccharides on the cell surface than ... |
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