text stringlengths 22 455 | relations listlengths 1 24 | messages listlengths 2 2 |
|---|---|---|
We describe 3 elderly patients with moderate to severe ataxia that occurred while they were taking propafenone. | [
{
"ade": "ataxia",
"drug": "propafenone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We describe 3 elderly patient... |
After other potential causes of liver toxicity were excluded, TMP-SMX was determined to be the cause of his acute liver toxicity. | [
{
"ade": "acute liver toxicity",
"drug": "TMP-SMX"
},
{
"ade": "liver toxicity",
"drug": "TMP-SMX"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: After other potential causes ... |
To our knowledge, four cases of interstitial pneumonitis associated with fludarabine have been reported in medical literature. | [
{
"ade": "interstitial pneumonitis",
"drug": "fludarabine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: To our knowledge, four cases ... |
A fatal case of pancytopenia due to levomepromazine. | [
{
"ade": "fatal case of pancytopenia",
"drug": "levomepromazine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A fatal case of pancytopenia ... |
Early peritoneal dialysis has not previously been reported for lisinopril induced multiorgan failure. | [
{
"ade": "multiorgan failure",
"drug": "lisinopril"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Early peritoneal dialysis has... |
Possible pathophysiological mechanisms which may have been operative in this case include: a direct central nervous system (CNS) toxic effect of valproic acid; a paradoxical epileptogenic effect secondary to the drug; and an indirect CNS toxic effect mediated through valproic acid-induced hyperammonemia. | [
{
"ade": "hyperammonemia",
"drug": "valproic acid"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Possible pathophysiological m... |
Three years later, treatment with ampicillin caused another episode of cholestatic hepatitis with cholestasis and duct paucity on rebiopsy. | [
{
"ade": "duct paucity",
"drug": "ampicillin"
},
{
"ade": "cholestasis",
"drug": "ampicillin"
},
{
"ade": "cholestatic hepatitis",
"drug": "ampicillin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Three years later, treatment ... |
Herpes simplex esophagitis in a renal transplant patient treated with cyclosporine A: a case report. | [
{
"ade": "Herpes simplex esophagitis",
"drug": "cyclosporine A"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Herpes simplex esophagitis in... |
Nitrendipine is an experimental calcium channel blocking agent that also appears to cause the side effect of drug-induced gingival hyperplasia. | [
{
"ade": "gingival hyperplasia",
"drug": "Nitrendipine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Nitrendipine is an experiment... |
His fever resolved, but he developed symptoms consistent with those of chloroquine toxicity. | [
{
"ade": "chloroquine toxicity",
"drug": "chloroquine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: His fever resolved, but he de... |
A 70-year-old man was admitted to our hospital because of dyspnea after taking an antihistaminic agent (homochlorcyclizine hydrochloride) for itching. | [
{
"ade": "dyspnea",
"drug": "homochlorcyclizine hydrochloride"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A 70-year-old man was admitte... |
Fixed drug eruption to rofecoxib. | [
{
"ade": "Fixed drug eruption",
"drug": "rofecoxib"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Fixed drug eruption to rofeco... |
Iatrogenic hypercalcemia due to vitamin D3 ointment (1,24(OH)2D3) combined with thiazide diuretics in a case of psoriasis. | [
{
"ade": "hypercalcemia",
"drug": "thiazide"
},
{
"ade": "hypercalcemia",
"drug": "1,24(OH)2D3"
},
{
"ade": "hypercalcemia",
"drug": "vitamin D3"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Iatrogenic hypercalcemia due ... |
Bromide intoxication secondary to pyridostigmine bromide therapy. | [
{
"ade": "Bromide intoxication",
"drug": "pyridostigmine bromide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Bromide intoxication secondar... |
A 67-year-old man developed diarrhea shortly after a 10-day course of oral ampicillin. | [
{
"ade": "diarrhea",
"drug": "ampicillin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A 67-year-old man developed d... |
Pleuropulmonary changes during treatment of Parkinson's disease with a long-acting ergot derivative, cabergoline. | [
{
"ade": "Pleuropulmonary changes",
"drug": "cabergoline"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Pleuropulmonary changes durin... |
Symptoms and endoscopic lesions quickly regressed within 1 week of meloxicam withdrawal. | [
{
"ade": "endoscopic lesions",
"drug": "meloxicam"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Symptoms and endoscopic lesio... |
Mineral oil, a hydrocarbon, may not elicit a normal protective cough reflex and may impair mucociliary transport. | [
{
"ade": "impair mucociliary transport",
"drug": "Mineral oil"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Mineral oil, a hydrocarbon, m... |
IFNalpha-induced recurrence of Graves' disease ten years after thyroidectomy in chronic viral hepatitis C. | [
{
"ade": "Graves' disease",
"drug": "IFNalpha"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: IFNalpha-induced recurrence o... |
The three reported cases demonstrate that troglitazone is an idiosyncratic hepatotoxin that can lead to irreversible liver injury. | [
{
"ade": "irreversible liver injury",
"drug": "troglitazone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The three reported cases demo... |
SLE receded after withdrawal of carbamazepine and treatment with anti-inflammatory drugs. | [
{
"ade": "SLE",
"drug": "carbamazepine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: SLE receded after withdrawal ... |
Conventional and diffusion-weighted MRI findings of methotrexate related sub-acute neurotoxicity. | [
{
"ade": "sub-acute neurotoxicity",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Conventional and diffusion-we... |
Elevated serum triglycerides with clozapine resolved with risperidone in four patients. | [
{
"ade": "Elevated serum triglycerides",
"drug": "clozapine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Elevated serum triglycerides ... |
Thrombocytosis associated with enoxaparin: A very rare cause in newborns. | [
{
"ade": "Thrombocytosis",
"drug": "enoxaparin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Thrombocytosis associated wit... |
The aim of this paper is to report the case of rosaceiform eruption induced by erlotinib in an 81-year-old-man and to discuss the pathogenetic role of Demodex folliculorum mites, found in the present patient, using skin scraping. | [
{
"ade": "rosaceiform eruption",
"drug": "erlotinib"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The aim of this paper is to r... |
PURPOSE: The occurrence of myoclonus associated with continuous i.v. infusion of dobutamine in a patient with end-stage renal disease (ESRD) is described. | [
{
"ade": "myoclonus",
"drug": "dobutamine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: PURPOSE: The occurrence of my... |
We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period. | [
{
"ade": "non-Hodgkin lymphoma",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We report one case of non-Hod... |
After taking cholestyramine II sachets twice daily for two months she presented with lethargy, confusion and drowsiness. | [
{
"ade": "lethargy",
"drug": "cholestyramine II"
},
{
"ade": "confusion",
"drug": "cholestyramine II"
},
{
"ade": "drowsiness",
"drug": "cholestyramine II"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: After taking cholestyramine I... |
Based on the clinical status of the patient, it was suspected that several conditions contributed to the abnormal hypersensitivity to warfarin. | [
{
"ade": "abnormal hypersensitivity",
"drug": "warfarin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Based on the clinical status ... |
Flecainide is a rare cause of hypersensitivity pneumonitis, and few cases have been reported. | [
{
"ade": "hypersensitivity pneumonitis",
"drug": "Flecainide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Flecainide is a rare cause of... |
We hypothesize that capecitabine-induced headache is vascular in nature. | [
{
"ade": "headache",
"drug": "capecitabine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We hypothesize that capecitab... |
Our findings suggest that significant progression of marrow reticulin fibrosis during imatinib therapy can be an indicator for a return or progression of CML and, in some patients with CML, imatinib may promote cytogenetic clonal evolution, resulting in a poor response to treatment. | [
{
"ade": "progression of marrow reticulin fibrosis",
"drug": "imatinib"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Our findings suggest that sig... |
The case of a bipolar patient who developed thyrotoxicosis with severe exophthalmos while on lithium therapy is described. | [
{
"ade": "thyrotoxicosis",
"drug": "lithium"
},
{
"ade": "severe exophthalmos",
"drug": "lithium"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The case of a bipolar patient... |
A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy. | [
{
"ade": "hepatitis",
"drug": "dapsone"
},
{
"ade": "lymphadenopathy",
"drug": "dapsone"
},
{
"ade": "vomiting",
"drug": "dapsone"
},
{
"ade": "nausea",
"drug": "dapsone"
},
{
"ade": "leukopenia",
"drug": "dapsone"
},
{
"ade": "fever",
"drug": "dap... | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A dapsone hypersensitivity sy... |
Although vasculitis has been reported in the course of hairy cell leukaemia, it has only rarely been reported as the consequence of cladribine treatment. | [
{
"ade": "vasculitis",
"drug": "cladribine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Although vasculitis has been ... |
FK506, which began to be administered 12 days earlier, rose to a level of 44 ng/mL (normal range, 10-20 ng/mL) 1 day before neurologic abnormalities began. | [
{
"ade": "neurologic abnormalities",
"drug": "FK506"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: FK506, which began to be admi... |
Vincristine induced cranial polyneuropathy. | [
{
"ade": "cranial polyneuropathy",
"drug": "Vincristine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Vincristine induced cranial p... |
The other patient developed transient intraoperative hypertension immediately after inadvertent submucosal injection of concentrated epinephrine. | [
{
"ade": "transient intraoperative hypertension",
"drug": "epinephrine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The other patient developed t... |
The association between heparin and priapism is often recognized; abnormal platelet aggregation could play a role in the pathogenesis of this side effect. | [
{
"ade": "priapism",
"drug": "heparin"
},
{
"ade": "abnormal platelet aggregation",
"drug": "heparin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The association between hepar... |
A 55-yr-old man developed prolonged jaundice and sicca complex after a course of thiabendazole therapy. | [
{
"ade": "sicca complex",
"drug": "thiabendazole"
},
{
"ade": "prolonged jaundice",
"drug": "thiabendazole"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A 55-yr-old man developed pro... |
Bulbar and pseudobulbar palsy complicating therapy with high-dose cytosine arabinoside in children with leukemia. | [
{
"ade": "Bulbar",
"drug": "cytosine arabinoside"
},
{
"ade": "pseudobulbar palsy",
"drug": "cytosine arabinoside"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Bulbar and pseudobulbar palsy... |
Hepatotoxicity of paracetamol enhanced by ingestion of alcohol: report of two cases. | [
{
"ade": "Hepatotoxicity",
"drug": "paracetamol"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Hepatotoxicity of paracetamol... |
Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis. | [
{
"ade": "Diffuse alveolar hemorrhage",
"drug": "leflunomide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Diffuse alveolar hemorrhage a... |
De novo absence status of late onset following withdrawal of lorazepam: a case report. | [
{
"ade": "De novo absence status",
"drug": "lorazepam"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: De novo absence status of lat... |
Hepatotoxicity after high-dose methylprednisolone for demyelinating disease. | [
{
"ade": "Hepatotoxicity",
"drug": "methylprednisolone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Hepatotoxicity after high-dos... |
Fulminant hepatic failure is a rare complication of disulfiram treatment for alcoholism. | [
{
"ade": "Fulminant hepatic failure",
"drug": "disulfiram"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Fulminant hepatic failure is ... |
We now present four cases of RSDS in kidney transplant recipients treated with tacrolimus. | [
{
"ade": "RSDS",
"drug": "tacrolimus"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We now present four cases of ... |
Ciprofloxacin-induced renal insufficiency in cystic fibrosis. | [
{
"ade": "renal insufficiency",
"drug": "Ciprofloxacin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Ciprofloxacin-induced renal i... |
Reinstitution of penicillamine treatment caused a recurrence thus proving a causal relationship between penicillamine and the described nail-changes. | [
{
"ade": "nail-changes",
"drug": "penicillamine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Reinstitution of penicillamin... |
Two cases of hypothyroidism in patients with chronic hepatitis C treated with recombinant alpha interferon are reported. | [
{
"ade": "hypothyroidism",
"drug": "recombinant alpha interferon"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Two cases of hypothyroidism i... |
Niacin causes a reversible toxic cystoid maculopathy that occurs in approximately 0.67% of patients taking high doses of the drug. | [
{
"ade": "reversible toxic cystoid maculopathy",
"drug": "Niacin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Niacin causes a reversible to... |
Docetaxel induced Meibomian duct inflammation and blockage is the likely cause of this presentation in a patient with no history of eyelid masses in the past. | [
{
"ade": "Meibomian duct inflammation and blockage",
"drug": "Docetaxel"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Docetaxel induced Meibomian d... |
The hypercalcemia responded to discontinuation of rhGH and a single dose of intravenous pamidronate disodium and has not recurred in 8 months of follow-up. | [
{
"ade": "hypercalcemia",
"drug": "rhGH"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The hypercalcemia responded t... |
Disseminated muscular cysticercosis with myositis induced by praziquantel therapy. | [
{
"ade": "myositis",
"drug": "praziquantel"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Disseminated muscular cystice... |
Colchicine-induced myopathy in renal failure. | [
{
"ade": "myopathy",
"drug": "Colchicine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Colchicine-induced myopathy i... |
Ifosfamide-induced nonconvulsive status epilepticus. | [
{
"ade": "nonconvulsive status epilepticus",
"drug": "Ifosfamide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Ifosfamide-induced nonconvuls... |
The photosensitivity is still present 3 years after the withdrawal of quinine. | [
{
"ade": "photosensitivity",
"drug": "quinine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The photosensitivity is still... |
To date, only three cases of seizures associated with amphotericin B have been reported in the literature, but healthcare providers should be aware of the potential for this rare adverse effect. | [
{
"ade": "seizures",
"drug": "amphotericin B"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: To date, only three cases of ... |
Reversal of ergotamine-induced arteriospasm by mechanical intra-arterial dilatation. | [
{
"ade": "arteriospasm",
"drug": "ergotamine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Reversal of ergotamine-induce... |
RESULTS: A clinical diagnosis of fixed drug eruption owing to use of the PDE5 inhibitor tadalafil (Cialis) was made. | [
{
"ade": "fixed drug eruption",
"drug": "tadalafil"
},
{
"ade": "fixed drug eruption",
"drug": "Cialis"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: RESULTS: A clinical diagnosis... |
Stupor from lamotrigine toxicity. | [
{
"ade": "Stupor",
"drug": "lamotrigine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Stupor from lamotrigine toxic... |
Carbamazepine-induced tics. | [
{
"ade": "tics",
"drug": "Carbamazepine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Carbamazepine-induced tics.",... |
The capacity of zuclopenthixol to induce priapism is thought to be due to its antagonist activity on alpha-adrenergic receptors. | [
{
"ade": "priapism",
"drug": "zuclopenthixol"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The capacity of zuclopenthixo... |
Triiodothyronine-induced thyrotoxicosis in ophthalmic Graves disease. | [
{
"ade": "thyrotoxicosis",
"drug": "Triiodothyronine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Triiodothyronine-induced thyr... |
The spectrum of renal lesions occurring during antituberculous therapy, particularly in association with rifampin, may be wider than previously suspected. | [
{
"ade": "renal lesions",
"drug": "rifampin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The spectrum of renal lesions... |
Successful desensitization to high-dose methotrexate after systemic anaphylaxis. | [
{
"ade": "systemic anaphylaxis",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Successful desensitization to... |
Succinylcholine-induced hyperkalemia in a patient with mucositis secondary to chemotherapy. | [
{
"ade": "hyperkalemia",
"drug": "Succinylcholine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Succinylcholine-induced hyper... |
Angioedema, a rare side effect of carbamazepine, involves vascular leakage in dermis and subcutis mediated by immunoglobulin E and/or bradykinins. | [
{
"ade": "Angioedema",
"drug": "carbamazepine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Angioedema, a rare side effec... |
This case is remarkable since 1) ECM developed after subcutaneous and not after intramuscular injection, 2) the injection was given by the patient himself, and 3) glatiramer acetate can induce skin necrosis as a side effect. | [
{
"ade": "skin necrosis",
"drug": "glatiramer acetate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: This case is remarkable since... |
In two patients clozapine was reinstated after risperidone was discontinued; serum triglyceride levels increased. | [
{
"ade": "serum triglyceride levels increased",
"drug": "clozapine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: In two patients clozapine was... |
We recommend the cautious use of ketorolac in patients with underlying illnesses where NSAID-induced ototoxicity could result in adverse otologic consequences. | [
{
"ade": "ototoxicity",
"drug": "ketorolac"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We recommend the cautious use... |
Children receiving zonisamide should be monitored for oligohidrosis and the development of neurological symptoms associated with an elevation of body temperature. | [
{
"ade": "neurological symptoms",
"drug": "zonisamide"
},
{
"ade": "oligohidrosis",
"drug": "zonisamide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Children receiving zonisamide... |
Administration of intrathecal Ara-C in the same dose over longer intervals within 3-5 days between consecutive doses resulted in mild, transient neurological symptoms (paresthesias) in only one of 30 patients so treated. | [
{
"ade": "paresthesias",
"drug": "Ara-C"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Administration of intrathecal... |
It is well-recognized that flucloxacillin may occasionally result in fatal hepatic injury. | [
{
"ade": "fatal hepatic injury",
"drug": "flucloxacillin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: It is well-recognized that fl... |
Upper tract urothelial malignancy after cyclophosphamide therapy: a case report and literature review. | [
{
"ade": "Upper tract urothelial malignancy",
"drug": "cyclophosphamide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Upper tract urothelial malign... |
Hypoglycemia can be a serious side effect of etanercept in patients already on antidiabetic medications known to cause hypoglycemia, such as sulfonylureas, meglitinides, and insulin. | [
{
"ade": "hypoglycemia",
"drug": "insulin"
},
{
"ade": "hypoglycemia",
"drug": "etanercept"
},
{
"ade": "Hypoglycemia",
"drug": "etanercept"
},
{
"ade": "hypoglycemia",
"drug": "meglitinides"
},
{
"ade": "hypoglycemia",
"drug": "sulfonylureas"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Hypoglycemia can be a serious... |
Nicotinic acid-induced fulminant hepatic failure. | [
{
"ade": "fulminant hepatic failure",
"drug": "Nicotinic acid"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Nicotinic acid-induced fulmin... |
We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following systemic chemotherapy with cisplatin (CDDP) and vindesine (VDS). | [
{
"ade": "syndrome of inappropriate secretion of antidiuretic hormone",
"drug": "cisplatin"
},
{
"ade": "SIADH",
"drug": "vindesine"
},
{
"ade": "syndrome of inappropriate secretion of antidiuretic hormone",
"drug": "CDDP"
},
{
"ade": "SIADH",
"drug": "CDDP"
},
{
... | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We report a patient with pulm... |
Hepatic reactions to cyclofenil. | [
{
"ade": "Hepatic reactions",
"drug": "cyclofenil"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Hepatic reactions to cyclofen... |
Physicians should be aware that indinavir nephrolithiasis may cause papillary necrosis. | [
{
"ade": "nephrolithiasis",
"drug": "indinavir"
},
{
"ade": "papillary necrosis",
"drug": "indinavir"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Physicians should be aware th... |
Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects. | [
{
"ade": "psychiatric side effects",
"drug": "interferon alpha"
},
{
"ade": "psychiatric side effects",
"drug": "IFN-alpha"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Treatment of chronic hepatiti... |
Anaphylactic reaction to bacitracin ointment. | [
{
"ade": "Anaphylactic reaction",
"drug": "bacitracin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Anaphylactic reaction to baci... |
Flecainide overdose can rapidly result in profound cardiovascular collapse, and is associated with a relatively high mortality. | [
{
"ade": "cardiovascular collapse",
"drug": "Flecainide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Flecainide overdose can rapid... |
D-penicillamine induced crescentic glomerulonephritis: report and review of the literature. | [
{
"ade": "crescentic glomerulonephritis",
"drug": "D-penicillamine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: D-penicillamine induced cresc... |
Fever caused by the use of furosemide was proved; the fever resolved after discontinuation of this medication and recurred after its reintroduction. | [
{
"ade": "Fever",
"drug": "furosemide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Fever caused by the use of fu... |
While undergoing treatment with albendazole, he developed worsening diarrhea with abdominal pain and fever. | [
{
"ade": "abdominal pain",
"drug": "albendazole"
},
{
"ade": "worsening diarrhea",
"drug": "albendazole"
},
{
"ade": "fever",
"drug": "albendazole"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: While undergoing treatment wi... |
STUDY DESIGN: Case reports are presented of three premature infants (mean gestational age 27 weeks) cared for in the intensive care nursery in whom clinically significant septal hypertrophy and left ventricular outflow tract obstruction developed during dexamethasone treatment for bronchopulmonary dysplasia. | [
{
"ade": "septal hypertrophy",
"drug": "dexamethasone"
},
{
"ade": "left ventricular outflow tract obstruction",
"drug": "dexamethasone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: STUDY DESIGN: Case reports ar... |
Adrenal suppression in a fetus due to administration of methylprednisolone has hitherto been rarely published. | [
{
"ade": "Adrenal suppression in a fetus",
"drug": "methylprednisolone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Adrenal suppression in a fetu... |
CONCLUSION: Significant ocular complications such as an irreversible decrease of visual acuity may develop in patients treated with pegylated interferon. | [
{
"ade": "ocular complications",
"drug": "pegylated interferon"
},
{
"ade": "irreversible decrease of visual acuity",
"drug": "pegylated interferon"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: CONCLUSION: Significant ocula... |
OBJECTIVE: To present a single case of zuclopenthixol-induced priapism and a literature review. | [
{
"ade": "priapism",
"drug": "zuclopenthixol"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: OBJECTIVE: To present a singl... |
We describe a patient who had a systemic allergic contact dermatitis to 8-MOP develop during her second course of PUVA treatment for psoriasis. | [
{
"ade": "systemic allergic contact dermatitis",
"drug": "8-MOP"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We describe a patient who had... |
Vitiligo associated with alpha-interferon in a patient with chronic active hepatitis C. | [
{
"ade": "Vitiligo",
"drug": "alpha-interferon"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Vitiligo associated with alph... |
The risk of cardiac decompensation in infants with supraventricular tachycardia and congestive cardiac failure should be kept in mind prior to administration of verapamil. | [
{
"ade": "cardiac decompensation",
"drug": "verapamil"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The risk of cardiac decompens... |
On day 7 of linezolid treatment, the patient developed severe pruritus, macular rash, facial edema, eosinophilia, marked increase in serum creatinine level, and mild hepatitis. | [
{
"ade": "facial edema",
"drug": "linezolid"
},
{
"ade": "marked increase in serum creatinine level",
"drug": "linezolid"
},
{
"ade": "eosinophilia",
"drug": "linezolid"
},
{
"ade": "severe pruritus",
"drug": "linezolid"
},
{
"ade": "mild hepatitis",
"drug": "... | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: On day 7 of linezolid treatme... |
Delayed neurotoxicity of intraventricular interleukin-2: a case report. | [
{
"ade": "neurotoxicity",
"drug": "interleukin-2"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Delayed neurotoxicity of intr... |
The second patient, who developed cholestasis after receiving trimethoprim-sulfamethoxazole, had marked duct paucity in the liver biopsy. | [
{
"ade": "duct paucity",
"drug": "trimethoprim-sulfamethoxazole"
},
{
"ade": "cholestasis",
"drug": "trimethoprim-sulfamethoxazole"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The second patient, who devel... |
Ten hours after the second methotrexate injection, the patient experienced a diffuse pruritic papular eruption located mainly on the limbs. | [
{
"ade": "diffuse pruritic papular eruption",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Ten hours after the second me... |
An association of granulocytopenia, eosinophilia, skin reaction and hepatitis during propylthiouracil (PTU) therapy for thyrotoxicosis in a 47 year old black female is reported. | [
{
"ade": "hepatitis",
"drug": "PTU"
},
{
"ade": "eosinophilia",
"drug": "propylthiouracil"
},
{
"ade": "hepatitis",
"drug": "propylthiouracil"
},
{
"ade": "granulocytopenia",
"drug": "PTU"
},
{
"ade": "skin reaction",
"drug": "propylthiouracil"
},
{
"a... | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: An association of granulocyto... |
Prolongation of the QT interval and ventricular tachyarrhymias have been described in patients on amiodarone therapy. | [
{
"ade": "Prolongation of the QT interval",
"drug": "amiodarone"
},
{
"ade": "ventricular tachyarrhymias",
"drug": "amiodarone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Prolongation of the QT interv... |
We report a case of Ritalin-associated cataract and glaucoma. | [
{
"ade": "cataract",
"drug": "Ritalin"
},
{
"ade": "glaucoma",
"drug": "Ritalin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We report a case of Ritalin-a... |
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