text stringlengths 22 455 | relations listlengths 1 24 | messages listlengths 2 2 |
|---|---|---|
PURPOSE: We studied a case of vortex keratopathy that was associated with the use of atovaquone. | [
{
"ade": "vortex keratopathy",
"drug": "atovaquone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: PURPOSE: We studied a case of... |
We describe a patient who, after receiving his first dose of pregabalin to relieve neuropathic pain, presented with a negative myoclonus. | [
{
"ade": "negative myoclonus",
"drug": "pregabalin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We describe a patient who, af... |
Cis-retinoic acid (RA) may further increase the risk of developing BMTN. | [
{
"ade": "BMTN",
"drug": "Cis-retinoic acid"
},
{
"ade": "BMTN",
"drug": "RA"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Cis-retinoic acid (RA) may fu... |
PURPOSE: Topiramate-induced angle-closure glaucoma (TiACG) is believed to be related to its sulfonamide moiety. | [
{
"ade": "angle-closure glaucoma",
"drug": "Topiramate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: PURPOSE: Topiramate-induced a... |
Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy. | [
{
"ade": "Acute reversible ataxo-myoclonic encephalopathy",
"drug": "flecainide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Acute reversible ataxo-myoclo... |
Intraventricular nafcillin-induced seizures in a neonate. | [
{
"ade": "seizures",
"drug": "nafcillin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Intraventricular nafcillin-in... |
Three days after intravitreal injection of bevacizumab, acute ocular ischemic syndrome occurred. | [
{
"ade": "acute ocular ischemic syndrome",
"drug": "bevacizumab"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Three days after intravitreal... |
The treatment for acidosis and hyperkalaemia should be started as soon as RTA is diagnosed, and the dosage of FK506 should also be reduced if possible. | [
{
"ade": "RTA",
"drug": "FK506"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The treatment for acidosis an... |
Clinicians have been aware of lithium toxicity for many years and traditionally have administered thiazide diuretics for lithium-induced polyuria and nephrogenic diabetes insipidus. | [
{
"ade": "nephrogenic diabetes insipidus",
"drug": "lithium"
},
{
"ade": "lithium toxicity",
"drug": "lithium"
},
{
"ade": "polyuria",
"drug": "lithium"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Clinicians have been aware of... |
Hypo-oestrogenic and anabolic/androgenic side-effects of danazol are well known by the gynaecologist and some of them are present in > 50% of patients being treated for endometriosis. | [
{
"ade": "Hypo-oestrogenic and anabolic/androgenic side-effects",
"drug": "danazol"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Hypo-oestrogenic and anabolic... |
CONCLUSION: We believe this to be the first reported case of rhGH-induced hypercalcemia in an HIV-infected patient. | [
{
"ade": "hypercalcemia",
"drug": "rhGH"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: CONCLUSION: We believe this t... |
Akathisia appeared to be a common side effect of fluoxetine and generally responded well to treatment with the beta-adrenergic antagonist propranolol, dose reduction, or both. | [
{
"ade": "Akathisia",
"drug": "fluoxetine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Akathisia appeared to be a co... |
This is the first report of a catatonic syndrome occurring in a patient receiving disulfiram treatment. | [
{
"ade": "catatonic syndrome",
"drug": "disulfiram"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: This is the first report of a... |
Acute myocardial infarction due to coronary spasm associated with L-thyroxine therapy. | [
{
"ade": "Acute myocardial infarction",
"drug": "L-thyroxine"
},
{
"ade": "coronary spasm",
"drug": "L-thyroxine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Acute myocardial infarction d... |
A 25-year-old woman sought medical attention because of iliocaval manifestations of retroperitoneal fibrosis while she was taking methysergide. | [
{
"ade": "retroperitoneal fibrosis",
"drug": "methysergide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A 25-year-old woman sought me... |
Sensorineural hearing loss due to quinine therapy for malaria has frequently been mentioned in the literature but has not been a subject of research during the last decades. | [
{
"ade": "Sensorineural hearing loss",
"drug": "quinine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Sensorineural hearing loss du... |
Hepatitis with bridging fibrosis and reversible hepatic insufficiency in a woman with rheumatoid arthritis taking methotrexate. | [
{
"ade": "Hepatitis",
"drug": "methotrexate"
},
{
"ade": "bridging fibrosis",
"drug": "methotrexate"
},
{
"ade": "reversible hepatic insufficiency",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Hepatitis with bridging fibro... |
Two patients are described who developed sensory neuropathy after the ingestion of 30.6 and 114 g metronidazole respectively. | [
{
"ade": "sensory neuropathy",
"drug": "metronidazole"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Two patients are described wh... |
OBJECTIVE: To describe a probable case of transient global amnesia caused by propafenone. | [
{
"ade": "transient global amnesia",
"drug": "propafenone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: OBJECTIVE: To describe a prob... |
We report a patient who developed acute pancreatitis during amiodarone therapy. | [
{
"ade": "acute pancreatitis",
"drug": "amiodarone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We report a patient who devel... |
The dose-limiting toxicity of KW-2149 is pulmonary toxicity. | [
{
"ade": "pulmonary toxicity",
"drug": "KW-2149"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The dose-limiting toxicity of... |
Graves' hyperthyroidism following transient thyrotoxicosis during interferon therapy for chronic hepatitis type C. | [
{
"ade": "transient thyrotoxicosis",
"drug": "interferon"
},
{
"ade": "Graves' hyperthyroidism",
"drug": "interferon"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Graves' hyperthyroidism follo... |
Severe systemic hypersensitivity reaction to ibuprofen occurring after prolonged therapy. | [
{
"ade": "Severe systemic hypersensitivity reaction",
"drug": "ibuprofen"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Severe systemic hypersensitiv... |
Cyclophosphamide pneumonitis. | [
{
"ade": "pneumonitis",
"drug": "Cyclophosphamide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Cyclophosphamide pneumonitis.... |
Paralytic ileus in patients undergoing bortezomib treatment has been reported, although a definite attribution to bortezomib administration has not been established. | [
{
"ade": "Paralytic ileus",
"drug": "bortezomib"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Paralytic ileus in patients u... |
The patient's defects may be due to methimazole teratogenicity or could represent a previously undescribed syndrome affecting ectodermal structures. | [
{
"ade": "teratogenicity",
"drug": "methimazole"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The patient's defects may be ... |
Comparable adverse effects, such as disorientation and temporary amnesia, have been reported in patients in the analogous agent, propranolol. | [
{
"ade": "temporary amnesia",
"drug": "propranolol"
},
{
"ade": "disorientation",
"drug": "propranolol"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Comparable adverse effects, s... |
This is the third report of reversible hepatic decompensation associated with prolonged MTX therapy in patients with rheumatoid arthritis. | [
{
"ade": "hepatic decompensation",
"drug": "MTX"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: This is the third report of r... |
HUS has been reported after several anticancer chemotherapies and most often after mitomycin C-based chemotherapy regimens. | [
{
"ade": "HUS",
"drug": "mitomycin C"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: HUS has been reported after s... |
Codeine intoxication in the neonate. | [
{
"ade": "Codeine intoxication",
"drug": "Codeine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Codeine intoxication in the n... |
Transient hemiparesis caused by phenytoin toxicity. | [
{
"ade": "Transient hemiparesis",
"drug": "phenytoin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Transient hemiparesis caused ... |
The use of beclomethasone diproprionate inhaler complicated by the development of an eosinophilic pneumonia reaction. | [
{
"ade": "eosinophilic pneumonia reaction",
"drug": "beclomethasone diproprionate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The use of beclomethasone dip... |
This report describes the first case of insulin-induced cardiac failure in a patient without underlying heart disease. | [
{
"ade": "cardiac failure",
"drug": "insulin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: This report describes the fir... |
Clinical, spectroscopic, and imaging abnormalities resolved with discontinuation of metronidazole. | [
{
"ade": "Clinical, spectroscopic, and imaging abnormalities",
"drug": "metronidazole"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Clinical, spectroscopic, and ... |
Mucosal pigmentation after oral lichen planus treatment with topical tacrolimus. | [
{
"ade": "Mucosal pigmentation",
"drug": "tacrolimus"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Mucosal pigmentation after or... |
We describe a 15-year-old female patient diagnosed with acute lymphoblastic leukemia presenting with status epilepticus after receiving intrathecal methotrexate. | [
{
"ade": "acute lymphoblastic leukemia",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We describe a 15-year-old fem... |
Captopril-induced lichen planus pemphigoides with pemphigus-like features. | [
{
"ade": "lichen planus pemphigoides",
"drug": "Captopril"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Captopril-induced lichen plan... |
Although they had complex medical problems, the high serum concentrations of ampicillin at the time of seizures without their recurrence after discontinuing the antibiotic suggest that the seizures were related to the ampicillin therapy. | [
{
"ade": "seizures",
"drug": "ampicillin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Although they had complex med... |
Quetiapine and obsessive-compulsive symptoms (OCS): case report and review of atypical antipsychotic-induced OCS. | [
{
"ade": "obsessive-compulsive symptoms",
"drug": "Quetiapine"
},
{
"ade": "OCS",
"drug": "Quetiapine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Quetiapine and obsessive-comp... |
In this report, we describe a patient receiving lenalidomide in whom dyspnea, fever, hypoxia, and diffuse pulmonary infiltrates developed. | [
{
"ade": "dyspnea",
"drug": "lenalidomide"
},
{
"ade": "hypoxia",
"drug": "lenalidomide"
},
{
"ade": "fever",
"drug": "lenalidomide"
},
{
"ade": "diffuse pulmonary infiltrates",
"drug": "lenalidomide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: In this report, we describe a... |
DISCUSSION: Colchicine, the most important drug in treatment of FMF, can cause myopathy in patients with impaired renal and hepatic function. | [
{
"ade": "myopathy",
"drug": "Colchicine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: DISCUSSION: Colchicine, the m... |
Radiation recall related to gemcitabine has been reported in lung and breast cancer. | [
{
"ade": "Radiation recall",
"drug": "gemcitabine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Radiation recall related to g... |
Asthma and urticaria during disodium cromoglycate treatment. | [
{
"ade": "urticaria",
"drug": "disodium cromoglycate"
},
{
"ade": "Asthma",
"drug": "disodium cromoglycate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Asthma and urticaria during d... |
We report a case of amiodarone-induced thyrotoxicosis of protracted duration, unresponsive to conventional thionamide therapy, with therapy limited by severe adverse drug reactions. | [
{
"ade": "thyrotoxicosis",
"drug": "amiodarone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We report a case of amiodaron... |
CONCLUSIONS: Symptoms and pathologic changes of colitis are associated with exposure to rofecoxib. | [
{
"ade": "colitis",
"drug": "rofecoxib"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: CONCLUSIONS: Symptoms and pat... |
A 51-year-old man developed type 1 diabetes mellitus following 24 weeks of treatment with recombinant alpha-2b peginterferon plus ribavirin for chronic hepatitis C. | [
{
"ade": "type 1 diabetes mellitus",
"drug": "ribavirin"
},
{
"ade": "type 1 diabetes mellitus",
"drug": "alpha-2b peginterferon"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A 51-year-old man developed t... |
A case of skeletal fluorosis induced by prolonged treatment with niflumic acid, a fast-acting non-steroid antiinflammatory agent, is reported in a 35-year-old woman suffering from rheumatoid arthritis and treated, in addition, with corticosteroids. | [
{
"ade": "skeletal fluorosis",
"drug": "niflumic acid"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A case of skeletal fluorosis ... |
Subsequently, he developed hyperglycemia (fasting blood glucose 138 mg/dL) that resolved when olanzapine was stopped and recurred (fasting blood glucose 150 mg/dL) after 2 days of rechallenge with olanzapine 2.5 mg twice daily. | [
{
"ade": "hyperglycemia",
"drug": "olanzapine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Subsequently, he developed hy... |
The clinical course suggests that caffeine, which is present in oolong tea, was mainly responsible for the rhabdomyolysis as well as the delirium, although severe hyponatremia has been reported to cause rhabdomyolysis on rare occasions. | [
{
"ade": "hyponatremia",
"drug": "caffeine"
},
{
"ade": "delirium",
"drug": "caffeine"
},
{
"ade": "rhabdomyolysis",
"drug": "caffeine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The clinical course suggests ... |
Can propofol precipitate pancreatitis in patients with Cushing's syndrome? | [
{
"ade": "pancreatitis",
"drug": "propofol"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Can propofol precipitate panc... |
OBSERVATIONS: A 48-year-old woman presented with disfiguring facial edema 10 weeks after she began antiviral therapy with peginterferon alfa-2a and ribavirin for chronic hepatitis C infection. | [
{
"ade": "disfiguring facial edema",
"drug": "ribavirin"
},
{
"ade": "disfiguring facial edema",
"drug": "peginterferon alfa-2a"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: OBSERVATIONS: A 48-year-old w... |
Reye-like syndrome following treatment with the pantothenic acid antagonist, calcium hopantenate. | [
{
"ade": "Reye-like syndrome",
"drug": "calcium hopantenate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Reye-like syndrome following ... |
This article describes the case of a 25-year-old man found dead at home who had been prescribed olanzapine for schizophrenia. | [
{
"ade": "dead",
"drug": "olanzapine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: This article describes the ca... |
Case 1, a 62-year-old woman, developed bilateral optic neuritis with decreased sensation of vibration and increased deep tendon reflex in the lower extremities after a seven-month use of recombinant interferon alpha-2a for chronic active hepatitis C. | [
{
"ade": "decreased sensation of vibration",
"drug": "recombinant interferon alpha-2a"
},
{
"ade": "bilateral optic neuritis",
"drug": "recombinant interferon alpha-2a"
},
{
"ade": "increased deep tendon reflex",
"drug": "recombinant interferon alpha-2a"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Case 1, a 62-year-old woman, ... |
Extensive forearm deep venous thrombosis following a severe infliximab infusion reaction. | [
{
"ade": "Extensive forearm deep venous thrombosis",
"drug": "infliximab"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Extensive forearm deep venous... |
Metronidazole neuropathy. | [
{
"ade": "neuropathy",
"drug": "Metronidazole"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Metronidazole neuropathy.",
... |
Diffusion-weighted MRI correlates of subacute methotrexate-related neurotoxicity. | [
{
"ade": "neurotoxicity",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Diffusion-weighted MRI correl... |
We report the case histories of identical twin brothers who developed concordant acute lymphoblastic leukemia at the age of 4 years and who later developed leukoencephalopathy and hydrocephalus related to central nervous system prophylaxis by, in the first case intrathecally administered methotrexate and, in the second... | [
{
"ade": "leukoencephalopathy",
"drug": "methotrexate"
},
{
"ade": "hydrocephalus",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We report the case histories ... |
Propecia-associated bilateral cataract. | [
{
"ade": "bilateral cataract",
"drug": "Propecia"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Propecia-associated bilateral... |
Subcutaneous IL-2 is safe and well tolerated, with a mortality rate <3%. | [
{
"ade": "mortality rate <3",
"drug": "IL-2"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Subcutaneous IL-2 is safe and... |
Spontaneous hemothorax following anticoagulation with low-molecular-weight heparin. | [
{
"ade": "Spontaneous hemothorax",
"drug": "heparin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Spontaneous hemothorax follow... |
Colchicine-induced rhabdomyolysis. | [
{
"ade": "rhabdomyolysis",
"drug": "Colchicine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Colchicine-induced rhabdomyol... |
To date, eight cases of TEN and one of SJS related to lamotrigine administration have been reported in the literature. | [
{
"ade": "TEN",
"drug": "lamotrigine"
},
{
"ade": "SJS",
"drug": "lamotrigine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: To date, eight cases of TEN a... |
Arrhythmias and cardiac arrest have been reported during amphotericin B administration but no effective technique has been described to prevent them. | [
{
"ade": "Arrhythmias",
"drug": "amphotericin B"
},
{
"ade": "cardiac arrest",
"drug": "amphotericin B"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Arrhythmias and cardiac arres... |
A patient with the Wolff-Parkinson-White syndrome presented with incessant orthodromic atrioventricular tachycardia following initiation of procainamide therapy. | [
{
"ade": "incessant orthodromic atrioventricular tachycardia",
"drug": "procainamide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A patient with the Wolff-Park... |
Life-threatening alterations in heart rate after the use of adenosine in atrial flutter. | [
{
"ade": "alterations in heart rate",
"drug": "adenosine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Life-threatening alterations ... |
The authors suggest that risperidone may increase affect in patients with schizophrenia and that some patients, especially those with anxiety, may have difficulty managing the increase. | [
{
"ade": "increase affect",
"drug": "risperidone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The authors suggest that risp... |
After extensive neurological 'work up', we realized that the anisocoria was related to the transdermal scopolamine patch that we had prescribed for weaning off the opioid. | [
{
"ade": "anisocoria",
"drug": "scopolamine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: After extensive neurological ... |
Patients with vitamin B12 deficiency are exceedingly sensitive to neurologic deterioration following nitrous oxide anesthesia. | [
{
"ade": "neurologic deterioration",
"drug": "nitrous oxide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Patients with vitamin B12 def... |
We report a case of interstitial pulmonary disease that occurred together with lymphocytic colitis during treatment with ticlopidine. | [
{
"ade": "interstitial pulmonary disease",
"drug": "ticlopidine"
},
{
"ade": "lymphocytic colitis",
"drug": "ticlopidine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We report a case of interstit... |
A woman 38-year-old, suffering for about ten years from multiple sclerosis and treated with repeated therapy cycles of intrathecal Depo-Medrol, developed a spastic paraparesis at the lower limbs. | [
{
"ade": "spastic paraparesis at the lower limbs",
"drug": "Depo-Medrol"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A woman 38-year-old, sufferin... |
After cessation of amantadine, the edema resolved, and the endothelial cell densities were <or=600/mm. | [
{
"ade": "edema",
"drug": "amantadine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: After cessation of amantadine... |
We describe a patient with androgen-independent prostate cancer in whom PSA continued to decrease for a period of 15 months after flutamide withdrawal. | [
{
"ade": "PSA continued to decrease",
"drug": "flutamide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: We describe a patient with an... |
After four months, while receiving RH, he developed painful bilateral gynaecomastia. | [
{
"ade": "bilateral gynaecomastia",
"drug": "RH"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: After four months, while rece... |
Since tamoxifen therapy can induce endometrial disorders, surveillance schemes of women taking tamoxifen have been recommended. | [
{
"ade": "endometrial disorders",
"drug": "tamoxifen"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Since tamoxifen therapy can i... |
Reversible methotrexate-associated lymphoproliferative disorder resembling advanced gastric cancer in a patient with rheumatoid arthritis. | [
{
"ade": "lymphoproliferative disorder",
"drug": "methotrexate"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Reversible methotrexate-assoc... |
Myotonia associated with sarcoidosis: marked exacerbation with pravastatin. | [
{
"ade": "Myotonia",
"drug": "pravastatin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Myotonia associated with sarc... |
The present observation suggests, that a batch of different testing doses, including lower testing doses may help to differentiate between an allergic type of contact dermatitis and an irritant type of reaction after treatment with calcipotriol. | [
{
"ade": "irritant type of reaction",
"drug": "calcipotriol"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The present observation sugge... |
Purple glove syndrome, named for its distinctive purple discoloration and swelling of the hands in the distribution of a glove, is an uncommon complication of intravenous phenytoin administration through small dorsal veins of the hands. | [
{
"ade": "purple discoloration",
"drug": "phenytoin"
},
{
"ade": "swelling of the hands",
"drug": "phenytoin"
},
{
"ade": "Purple glove syndrome",
"drug": "phenytoin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Purple glove syndrome, named ... |
Intravenous sodium bicarbonate appears to be indicated prophylactically in combating the associated metabolic acidosis due to absorbed formic acid. | [
{
"ade": "metabolic acidosis",
"drug": "formic acid"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Intravenous sodium bicarbonat... |
Significant clinical improvement of the porphyria followed withdrawal of the diphenylhydantoin. | [
{
"ade": "porphyria",
"drug": "diphenylhydantoin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Significant clinical improvem... |
It is thought that the clinico-pathological features and chronology of this case bore the hallmarks of the so-called "3-week sulphasalazine syndrome", a rare, but often fatal, immunoallergic reaction to sulphasalazine. | [
{
"ade": "sulphasalazine syndrome",
"drug": "sulphasalazine"
},
{
"ade": "fatal",
"drug": "sulphasalazine"
},
{
"ade": "immunoallergic reaction",
"drug": "sulphasalazine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: It is thought that the clinic... |
Diarrhoea, T-CD4+ lymphopenia and bilateral patchy pulmonary infiltrates developed in a male 60 yrs of age, who was treated with oxaliplatinum and 5-fluorouracil for unresectable rectum carcinoma. | [
{
"ade": "Diarrhoea",
"drug": "oxaliplatinum"
},
{
"ade": "Diarrhoea",
"drug": "5-fluorouracil"
},
{
"ade": "T-CD4+ lymphopenia",
"drug": "5-fluorouracil"
},
{
"ade": "T-CD4+ lymphopenia",
"drug": "oxaliplatinum"
},
{
"ade": "bilateral patchy pulmonary infiltrates... | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Diarrhoea, T-CD4+ lymphopenia... |
Baclofen withdrawal: a cause of prolonged fever in the intensive care unit. | [
{
"ade": "fever",
"drug": "Baclofen"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Baclofen withdrawal: a cause ... |
CONCLUSION: The administration of tissue plasminogen activator was responsible for the large extent of hemorrhage and should be considered in the differential diagnosis of hemorrhagic choroidal detachment. | [
{
"ade": "hemorrhagic choroidal detachment",
"drug": "tissue plasminogen activator"
},
{
"ade": "hemorrhage",
"drug": "tissue plasminogen activator"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: CONCLUSION: The administratio... |
Idiosyncratic factors involving vasopressin receptor affinity and distribution, vasopressin-associated vasodilation in some vascular beds, and the effect of vasopressin on the renin-angiotensin system may further contribute to impaired tissue perfusion. | [
{
"ade": "impaired tissue perfusion",
"drug": "vasopressin"
},
{
"ade": "vasodilation",
"drug": "vasopressin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Idiosyncratic factors involvi... |
Fatal intravascular autoimmune hemolytic anemia after fludarabine treatment for chronic lymphocytic leukemia. | [
{
"ade": "Fatal intravascular autoimmune hemolytic anemia",
"drug": "fludarabine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Fatal intravascular autoimmun... |
One patient was an 80-year-old woman who was admitted for Staphylococcus aureus knee arthritis after several intraarticular injections of sodium hyaluronate and corticosteroids. | [
{
"ade": "Staphylococcus aureus knee arthritis",
"drug": "sodium hyaluronate"
},
{
"ade": "Staphylococcus aureus knee arthritis",
"drug": "corticosteroids"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: One patient was an 80-year-ol... |
High-grade endometrial stromal sarcoma after tamoxifen therapy for breast cancer. | [
{
"ade": "High-grade endometrial stromal sarcoma",
"drug": "tamoxifen"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: High-grade endometrial stroma... |
Psychotic disorder associated with isoniazid. | [
{
"ade": "Psychotic disorder",
"drug": "isoniazid"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Psychotic disorder associated... |
However, a recent post-marketing survey in Japan revealed that interstitial pneumonia occurred in 4 among approximately 2 000 Japanese patients treated with sorafenib. | [
{
"ade": "interstitial pneumonia",
"drug": "sorafenib"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: However, a recent post-market... |
Toxicity related to chloroquine treatment of resistant vivax malaria. | [
{
"ade": "Toxicity",
"drug": "chloroquine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Toxicity related to chloroqui... |
A 10-year-old boy with osteosarcoma and normal renal function manifested laboratory evidence of impending renal toxicity and extreme elevation of aspartate aminotrasferase and alanine aminotransferase within 2 hours after the completion of a 4-hour infusion of high-dose methotrexate (MTX) (12 g/m2), and went on to deve... | [
{
"ade": "acute renal failure",
"drug": "MTX"
},
{
"ade": "acute renal failure",
"drug": "methotrexate"
},
{
"ade": "elevation of aspartate aminotrasferase",
"drug": "methotrexate"
},
{
"ade": "elevation of aspartate aminotrasferase",
"drug": "MTX"
},
{
"ade": "re... | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: A 10-year-old boy with osteos... |
OBJECTIVE: To describe a case of cefazolin-induced leukopenia in a critically ill patient who developed this adverse reaction upon rechallenge with cefoxitin. | [
{
"ade": "leukopenia",
"drug": "cefazolin"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: OBJECTIVE: To describe a case... |
Delayed hypersensitivity to flurbiprofen. | [
{
"ade": "Delayed hypersensitivity",
"drug": "flurbiprofen"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Delayed hypersensitivity to f... |
However, recurrent staphylococcus aureus sepsis developed during CyA therapy. | [
{
"ade": "staphylococcus aureus sepsis",
"drug": "CyA"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: However, recurrent staphyloco... |
The probable proarrhythmic action of amiodarone, although rare, is reviewed along with a discussion of the novel use of intravenous magnesium sulfate therapy. | [
{
"ade": "proarrhythmic",
"drug": "amiodarone"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: The probable proarrhythmic ac... |
This is the first report of acute kidney injury due to zonisamide-induced DRESS/DIHS. | [
{
"ade": "DRESS",
"drug": "zonisamide"
},
{
"ade": "DIHS",
"drug": "zonisamide"
},
{
"ade": "acute kidney injury",
"drug": "zonisamide"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: This is the first report of a... |
Slow acetylator genotypes as a possible risk factor for infectious mononucleosis-like syndrome induced by salazosulfapyridine. | [
{
"ade": "infectious mononucleosis-like syndrome",
"drug": "salazosulfapyridine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Slow acetylator genotypes as ... |
Thrombotic thrombocytopenic purpura (TTP) developed in a patient with seropositive rheumatoid arthritis (RA) after 2 1/2 months of treatment with penicillamine. | [
{
"ade": "TTP",
"drug": "penicillamine"
},
{
"ade": "Thrombotic thrombocytopenic purpura",
"drug": "penicillamine"
}
] | [
{
"content": "Extract all the adverse drug effects(ADE) for each of the drugs in the TEXT\n and output them in a list of JSON as 'RELATIONS: ['ade': '*extract adverse effect here*', 'drug': '*extract drug name here*']' for all of the drugs in the TEXT. ### TEXT: Thrombotic thrombocytopenic p... |
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