OpenPhase / README.md
kevinhyj
docs: update PhaseFlow GitHub link
6ca66db
|
Raw
History Blame Contribute Delete
2.59 kB
metadata
pretty_name: OpenPhase
license: other
viewer: false
tags:
  - protein
  - peptide
  - liquid-liquid-phase-separation
  - disordered-protein-regions
  - tabular

OpenPhase

PhaseFlow: sequence data to phase-behaviour learning

This repository groups three PhaseFlow research-data packages:

Package Task Primary data
llps/ Protein-level LLPS learning Canonical proteins, training units, fixed training plans, and evaluation inputs.
dpr/ Driving phase-separation region supervision Protein records, region supervision, training schedules, and evaluation inputs.
peptide/ Short-peptide 4×4 PSSI phase-diagram modelling The verified PhaseFlow input table and its preprocessing script.

Related resources

Resource Link Role
PhaseFlow code github.com/GENTEL-lab/PhaseFlow Installation, inference scripts, configurations, and documentation
Unified checkpoint GENTEL-Lab/PhaseFlow Combined peptide, full-protein, and DPR runtime weights
Online demo phaseflow.bio Interactive PhaseFlow usage

Open access

All data and accompanying preprocessing materials in this repository are fully open source and freely available to the community. We warmly welcome their use in research, benchmarking, method development, and reproducible studies. Please cite the relevant PhaseFlow work and retain appropriate source attribution when using or redistributing the data.

Benchmark inputs remain physically separated and must not be used for training, feature selection, threshold tuning, or checkpoint selection.

Integrity

Each package contains metadata/file_inventory.csv. Verify all listed files before use; the inventory intentionally excludes itself to avoid a self-referential checksum.

import csv
import hashlib
from pathlib import Path

package = Path("llps")
with (package / "metadata/file_inventory.csv").open(newline="") as handle:
    for item in csv.DictReader(handle):
        digest = hashlib.sha256((package / item["path"]).read_bytes()).hexdigest()
        assert digest == item["sha256"], item["path"]

Responsible use

These data are research resources, not clinical or diagnostic tools. Sequence labels and benchmark annotations require independent validation and must be interpreted under the documented evidence and coordinate conventions.