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1330940eeadc873bedff039980c0d1e7fbcdff6f
chelpanov received his primary education in mariupol at
chelpanov received his primary education in mariupol at the local parish school, and then studied at the gymnasium alexandrinum (mariupol), graduating in 1883 with a gold medal. after graduating from the gymnasium, he entered the faculty of history and philology of the novorossiysk university in odessa and graduated in...
wikipedia
8fe464f252203b3616509d6956560bd8f56f70b4
georgy ivanovich chelpanov (russian: Георгий Иванович Челпанов; 28
georgy ivanovich chelpanov (russian: Георгий Иванович Челпанов; 28 april 1862 – 13 february 1936) was a russian imperial and soviet psychologist, philosopher and logician.
wikipedia
a9e42b60e768a3a0a75c03e928e566af771cd639
chlorine trifluoride is an interhalogen compound with the
chlorine trifluoride is an interhalogen compound with the formula clf3. it is a colorless, poisonous, corrosive, and extremely reactive gas that condenses to a pale-greenish yellow liquid, the form in which it is most often sold. it is famous for its extreme oxidation properties. the compound is primarily of interest i...
wikipedia
8e40abde44893b0e4ccf3e7fd141fe7a9633644d
exposure to larger amounts of clf, as a
exposure to larger amounts of clf, as a liquid or as a gas, ignites living tissue, resulting in severe chemical and thermal burns. clf reacts violently with water and exposure to the reaction also results in burns. the products of hydrolysis are mainly hydrofluoric acid and hydrochloric acid, which are usually released...
wikipedia
f241e528fb7e6c9386160ff2f7cd40bea9414344
this oxidizing power, surpassing that of oxygen, causes
this oxidizing power, surpassing that of oxygen, causes clf to react vigorously with many other materials often thought of as incombustible and refractory. it ignites sand, asbestos, glass, and even ashes of substances that have already burned in oxygen. in one particular industrial accident, a spill of 900 kg of clf b...
wikipedia
a3bad1dbf7aa9594d3ba3707beff45146532058a
clf is a very strong oxidizer. it is
clf is a very strong oxidizer. it is extremely reactive with most inorganic and organic materials and will combust many otherwise non-flammable materials without any ignition source. these reactions are often violent and in some cases explosive. steel, copper, and nickel are not consumed because a passivation layer of ...
wikipedia
581e888b8b1528c0d5c794eb6d7dcc998c695d5c
under the code name n-stoff ("substance n"), chlorine
under the code name n-stoff ("substance n"), chlorine trifluoride was investigated for military applications by the kaiser wilhelm institute in nazi germany not long before the start of world war ii. tests were made against mock-ups of the maginot line fortifications, and it was found to be an extremely effective incen...
wikipedia
d5338ec353d34ce4b682db1f74b0f2b8a51c6f52
chlorine pentafluoride (clf) has also been investigated as
chlorine pentafluoride (clf) has also been investigated as a potential rocket oxidizer. it offered improved specific impulse over chlorine trifluoride, but with all of the same difficulties in handling. neither compound has been used in any operational rocket propulsion system.
wikipedia
2b86f89fdc12be15e5f26aed8f46c23d2e88751e
it is, of course, extremely toxic, but that's
it is, of course, extremely toxic, but that's the least of the problem. it is hypergolic with every known fuel, and so rapidly hypergolic that no ignition delay has ever been measured. it is also hypergolic with such things as cloth, wood, and test engineers, not to mention asbestos, sand, and water —with which it reac...
wikipedia
d8865e41cc2f8fd9b56a6b3aa370e03a238d5aa1
chlorine trifluoride has been investigated as a high-performance
chlorine trifluoride has been investigated as a high-performance storable oxidizer in rocket propellant systems. handling concerns, however, severely limit its use. the following passage by rocket scientist john d. clark is widely quoted in descriptions of the substance's extremely hazardous nature:
wikipedia
0d4b1e7536e9d4ed832c194a02c6307e02f280fe
in the semiconductor industry, chlorine trifluoride is used
in the semiconductor industry, chlorine trifluoride is used to clean chemical vapour deposition chambers. it can be used to remove semiconductor material from the chamber walls without the need to dismantle the chamber. unlike most of the alternative chemicals used in this role, it does not need to be activated by the ...
wikipedia
f6c92d21122200039e24cd80a49ffa35a67680d8
the molecular geometry of clf is approximately t-shaped,
the molecular geometry of clf is approximately t-shaped, with one short bond (1.598 Å) and two long bonds (1.698 Å). this structure agrees with the prediction of vsepr theory, which predicts lone pairs of electrons as occupying two equatorial positions of a hypothetic trigonal bipyramid. the elongated cl-f axial bonds ...
wikipedia
02241cefb8a1498471de8aab7dfb613d2cd6f1bb
chlorine trifluoride is an interhalogen compound with the
chlorine trifluoride is an interhalogen compound with the formula clf. it is a colorless, poisonous, corrosive, and extremely reactive gas that condenses to a pale-greenish yellow liquid, the form in which it is most often sold (pressurized at room temperature). it is famous for its extreme oxidation properties. the co...
wikipedia
7a127868ee80d3c3425248bba9a5482fb7472770
the 1946 great britain lions tour was a
the 1946 great britain lions tour was a tour by the great britain national rugby league team of australia and new zealand which took place between april and august 1946. the tour involved a schedule of 27 games: 20 in australia including a three-test series against australia for the ashes, and a further 7 in new zealan...
wikipedia
4f1e6f1667263aab387707cb62d552ef2aa16544
all 26 players appeared at some point on
all 26 players appeared at some point on the tour. harry murphy was unlucky and broke a collarbone during the match against group 8 which ruled him out of the rest of the tour having played just the single match. martin ryan also missed most of the tour after being diagnosed with a hernia which required an operation an...
wikipedia
6f5b0ea7b0ea831138a4be164d82adc87b17bdc6
net receipts for the tour were £46,312 (£38,226
net receipts for the tour were £46,312 (£38,226 from the australian matches and £8,085 from the new zealand leg) of which england's share was £27,782 (60%). expenses and allowances to the players and their families amounted to £18,145 leaving a profit of £9,647. of this a third was split between the squad who therefore...
wikipedia
72ef2f9072c71fac51f53284158f0e67da8b300d
the second half coincided with more rain that
the second half coincided with more rain that hampered ball-handling for the rest of the game. england came back with tries by eric batten and ernest ward to equalise. ward then kicked a penalty to put england ahead before new zealand took a winning lead as bruce graham scored a try after catching a clarke penalty atte...
wikipedia
e35429cfe1896649ba77e610322b995acc652445
the sole test match in new zealand was
the sole test match in new zealand was played at a rain-soaked carlaw park in auckland on 10 august 1946. england gave test debuts to three players; joe jones, trevor foster and bryn knowelden while the entire new zealand team were previously uncapped.
wikipedia
0ffe6ac80f2004aad092d33b5ebb7a6b21c5d136
with the ashes already decided the game at
with the ashes already decided the game at sydney cricket ground on 20 july was about pride for both teams and the match was hotly contested from the start. almost a quarter of the game had gone before either side scored and it was australia who took the lead as joe jorgenson kicked a penalty. england equalised with a ...
wikipedia
49ec3e946e11b038933ebe2019d026d412f27788
england came into the game making two changes
england came into the game making two changes from the previous test. prop frank whitcombe was replaced by george curran and eric batten was recalled to the wing. australia made five changes with trevor eather, noel white and clem kennedy being called up into the backs while jim armstrong and noel mulligan came into th...
wikipedia
cbf94a627c1a59d00d9c663a8193c389768e15f6
the attendance was officially recorded as 40,500 but
the attendance was officially recorded as 40,500 but estimates are that the number watching was closed to 60,000 when the gatecrashers and members of the royal national agricultural and industrial association of queensland (owners of the ground) are included.
wikipedia
e2553263270bf9a58eda8a09ade8f4005c796f01
with england starting the second half with a
with england starting the second half with a 5–0 lead, australia had to score first to get back into the game and minutes into the second half they did so as jorgenson put a penalty over to make the score 5–2. shortly afterwards though bassett scored his second try to increase england's lead to six points. australia ca...
wikipedia
108e936f31c58d1017afbdbaaea38d228d6c01de
when the match started it was a closely
when the match started it was a closely contested game for the first quarter before england opened scoring as debutant arthur bassett gained possession from a mccue kick to score a try on the wing. the only other points of the first half were from ernest ward's boot as he scored a penalty from outside the australian 25...
wikipedia
a3a62df7cf3f4c5107ef145c951a7c122dfafa2f
the game was played at the brisbane exhibition
the game was played at the brisbane exhibition ground on 6 july 1946. despite a public transport strike and continuing restrictions on non-essential travel, huge queues had formed outside the ground by early morning and the gates were opened at 7 am, several hours before kick off. by 10 am the ground was full and the g...
wikipedia
c1764929d7cd88df9c78e370ebcb358aadfe9a9c
after the drawn test in sydney, england only
after the drawn test in sydney, england only needed to win the second test to retain the ashes as a tied series would result in the holders keeping the trophy. australia made just one change to their side with loose forward jack hutchinson replacing the injured noel mulligan; the captaincy also changed as ron bailey su...
wikipedia
7bdb839a486b76272d430f89789a469cfe7e201b
after the game kitching said he had pushed
after the game kitching said he had pushed jorgenson away and claimed he had been bitten. jorgenson denied he had bitten kitching and the judicial committee of the new south wales rugby league agreed dismissing kitching's claim without hearing from jorgenson and cautioning kitching for punching. with this kitching and ...
wikipedia
324b75eaf0f60cec0f95e9d6b316701fb0017c55
in the second half, with england disorganised after
in the second half, with england disorganised after kitching's dismissal, australia fought back and brought the score to 6–5 with a try by centre ron bailey. england extended struck back as risman kicked a penalty but with ten minutes left australia equalised as winger lionel cooper scored a try. in the closing minutes...
wikipedia
a76709e3470b44f7a985cd4995f91e5b2d602136
the game kicked off as scheduled and england
the game kicked off as scheduled and england took an early lead as stand-off willie horne scored a try in only the third minute after picking up a wayward australian pass close to the australian line. risman missed the conversion, the first of several misses in his kicking game during the match. australian captain joe ...
wikipedia
f7b1ccb6433b55bc6608bccb88158c4439c8c816
the first test was played at sydney cricket
the first test was played at sydney cricket ground on 17 june 1946. queues to get into the ground started the previous evening and by 7:30 am on the morning of the test the australian authorities felt it necessary to open the gates to the ground several hours early and by 11:30 am the ground was full.
wikipedia
e722058258ecc26dbbe22f35ac0080bdc28590f6
the third test was the final match of
the third test was the final match of the australian leg of the tour. to transfer to new zealand it had been arranged for the team to fly, the size of the aircraft involved made it necessary for the party to travel by three separate flights from rose bay water airport on 22, 23 and 24 july.
wikipedia
1e4b26d3a247f6e214c52d96a65f683860c78627
prior to leaving fremantle the squad played an
prior to leaving fremantle the squad played an exhibition match, fulfilling a commitment made to the captain of the indomitable during the voyage; splitting into two teams, mccue's "reds" beat risman's "blues" 24–5. a collection for naval charities raised £44 to which the rfl added £10/10.
wikipedia
ffaeb13f44e78e5420f4c3395518aaec3de49b8d
the squad sailed from devonport on 3 april
the squad sailed from devonport on 3 april 1946 and arrived in fremantle on 30 april. indomitable was supposed to continue to sydney but for operational reasons the voyage was curtailed at fremantle. the team as well as a large number of navy personnel and returning australian and new zealand soldiers were disembarked ...
wikipedia
7e04424fc7120d487f0dccf89b37179bd35fcb20
the tour was also the first with an
the tour was also the first with an official press presence. three british news reporters, ernest crawthorne of the manchester evening news, alfred drewery of the yorkshire post and eddie waring of the sunday pictorial all accompanied the team on the voyage and around australia and new zealand. once in australia they w...
wikipedia
9ee4815bbdba2026d7de270dfe8e8cc325a66467
following the announcement of the squad the rugby
following the announcement of the squad the rugby football league (rfl) entered into discussions with the war office over leave of absence for white, phillips and ernie ward as all three were still serving soldiers. initially the war office refused permission for white and phillips, but following representations to the...
wikipedia
f6eba8f949fc5b00b5340679b9a5f4beacb0afc0
the team manager was w. poppleton of bramley
the team manager was w. poppleton of bramley and w. gabbatt of barrow was the business manager. w. crockford of hull kingston rovers represented the rugby football league council, although he was not officially a member of the squad management and was paying his own way.
wikipedia
3e9a93eba97e59ad3660cf1d526b22690d9aa315
on previous tours it had been the practice
on previous tours it had been the practice for every playing position to be duplicated in player selection to cover for injuries but this practice was not followed for this tour, with 15 backs and only 11 forwards selected, including five centres and only three prop-forwards. the 26 man squad was announced in march 194...
wikipedia
683262c7c7a1b514fff90c067931bb2e3c65433b
travel to and from new zealand was also
travel to and from new zealand was also an issue. again the shortage of commercial shipping was the problem and in june the new zealand leg of the tour was in jeopardy because of the unavailability of a ship back to britain until the end of august. arrangements were made for some of the squad to fly to auckland from sy...
wikipedia
cc9780903232018fdd3573b9f3218d61899777e4
the issue of transport to australia almost resulted
the issue of transport to australia almost resulted in the tour being cancelled; the travel arrangements were the responsibility of the australian authorities who were unable to find passage on a commercial ship. as late as the beginning of march 1946 there was a likelihood that the tour would not go ahead. eventually ...
wikipedia
d68fe1328ee2d9f6561ffd442e5e28a4dff7cd42
in september 1945 the australian minister for external
in september 1945 the australian minister for external affairs, h. v. evatt issued an invitation to the rugby football league (rfl) to send a team to australia during the summer of 1946. the rfl were at first unsure about accepting due to the state of the game in britain after the war but after consulting with the club...
wikipedia
223ab6ebf9bd2b9020d8220f1ef9a65531e60038
despite being a british team – 11 of
despite being a british team – 11 of the squad were welsh – the team played, and were often referred to by both the press at home and away, as england. the team became known by the nickname the indomitables due to their travelling to australia on-board the aircraft carrier hms indomitable.
wikipedia
b3d6a5caa91b136544b64c7b2a1cc909072f1b27
captained by gus risman, the lions returned home
captained by gus risman, the lions returned home having won 21, drawn 1 and lost 5 of their games. the team lost the test match against new zealand but in winning the ashes against australia 2–0 (with one match drawn) they became the only great britain team to date to be unbeaten in a test series against australia in a...
wikipedia
2699e22dc2fabb0ac769ea5392ac6879010d2245
the 1946 great britain lions tour was a
the 1946 great britain lions tour was a tour by the great britain national rugby league team of australia and new zealand which took place between april and august 1946. the tour involved a schedule of 27 games: 20 in australia including a three-test series against australia for the ashes, and a further 7 in new zealan...
wikipedia
d4709da11cc49e4be079cb3f662ba11eb502dbc0
the 2019–20 season was lori fc's second season
the 2019–20 season was lori fc's second season in the armenian premier league, and they will also participate in the armenian cup. they finished the season in 5th position and reached the quarterfinals of the armenian cup where they were knocked out by urartu.
wikipedia
1caede52d0a248abfe0b26f515638c7077dabba4
on 10 july, lori announced that 17 of
on 10 july, lori announced that 17 of the players and staff had tested positive for covid-19, and as a result the whole club was now isolating, as a result their lat game of the season, scheduled for 14 july against ararat yerevan was cancelled with the points not being awarded to either team.
wikipedia
956d8cbcc67694d4d02d152ead801286bc3ee425
on 2 june 2020, lori announced that manager
on 2 june 2020, lori announced that manager david campaña and his assistants francisco compan, jorge gomez, agustin perez and enrique gil had all left the club as their contracts could not be extended due to travel restrictions in returning to armenia due to the covid-19 pandemic. later the same day, armen sanamyan was...
wikipedia
a55fab29bbd0b76d74f6f1666191452577543179
the 2019–20 season was lori fc 's second
the 2019–20 season was lori fc 's second season in the armenian premier league, and they will also participate in the armenian cup. they finished the season in 5th position and reached the quarterfinals of the armenian cup where they were knocked out by urartu.
wikipedia
565a11a680661f8d91df629bd10998dfc2cd5c78
radim bičánek is a czech former professional ice
radim bičánek is a czech former professional ice hockey defenceman who played in the national hockey league (nhl). he was drafted in the second round, 27th overall, by the ottawa senators in the 1993 nhl entry draft.
wikipedia
ada4fdef32078d594e02fef3fb3c4ab7446dc869
during the 2004–05 nhl lockout, bičánek returned to
during the 2004–05 nhl lockout, bičánek returned to the czech republic to play for hc jme znojemští orli. after five seasons in znojmo he moved to hc kometa brno.
wikipedia
423271fbd3949cbf7e46d873bf10186d65a86e65
after appearing sparingly for the senators during the
after appearing sparingly for the senators during the 1997–98 and 1998–99 seasons, bičánek was traded to the chicago blackhawks on march 12, 1999, in exchange for a pick in the 1999 nhl entry draft. the blackhawks left him unprotected for the 2000 nhl expansion draft, allowing him to be selected by the columbus blue ja...
wikipedia
756e94149e685983eba7cfab51a6f687dd9b1f41
after playing two seasons in the ontario hockey
after playing two seasons in the ontario hockey league for the belleville bulls, bičánek made his national hockey league debut with the senators in the 1994–95 season, appearing in six games. he went on to spend the entire 1995–96 season with the senators' american hockey league affiliate, the prince edward island sena...
wikipedia
17069a4092ef3f8efb595c17d34f91b2a938a4ff
radim bičánek (born january 18, 1975) is a
radim bičánek (born january 18, 1975) is a czech former professional ice hockey defenceman who played in the national hockey league (nhl). he was drafted in the second round, 27th overall, by the ottawa senators in the 1993 nhl entry draft.
wikipedia
374b7d25075489e3352b6767bb8c02dc4436fc0f
andré clarindo dos santos is a brazilian former
andré clarindo dos santos is a brazilian former professional footballer who played as a left-back, but was also utilised as an attacking midfielder or left winger. on 15 june 2009, he made his first international appearance as a substitute in a match against egypt. santos participated and helped brazil capture the 2009...
wikipedia
c043a88e9ed57d5797cfa8a223531d020ad289a1
on 21 may 2009, he was called up
on 21 may 2009, he was called up for the first time to the brazil national team for 2010 fifa world cup qualification and the 2009 fifa confederations cup in south africa. on 15 june 2009, he made his first international appearance as a substitute in a match against egypt. he then started the following four games as br...
wikipedia
31b8bd4da69a44b50ea29e880953b68ed69c3147
on 29 september 2014, santos joined indian super
on 29 september 2014, santos joined indian super league side fc goa. santos had a very successful season with goa, as he led them to the semi-finals. as goa's key player, he scored 4 goals and provided 3 assists in the tournament.
wikipedia
6ba1dac8f3b0864740f286a2402ff6ac76dd84c4
on 20 july 2014, santos was attacked by
on 20 july 2014, santos was attacked by a flamengo fan following his poor performance in their 4–0 loss against internacional. the loss meant flamengo had accumulated 7 points in 11 games and the incident left santos in hospital.
wikipedia
a4407ec077c14ea155b77f99116e873ba21e0592
on 10 february 2013, santos moved to porto
on 10 february 2013, santos moved to porto alegre after signing a one-year loan deal (with the option for arsenal to recall him after 6 months) with grêmio. he was contracted with the club to play in the libertadores.
wikipedia
32329ab73229bdfd9d192c6bb7485b96e9e39392
on 13 may, he scored the equalising goal
on 13 may, he scored the equalising goal against west bromwich albion, levelling the score at 2–2. arsenal went on to win the match 3–2 thanks to a laurent koscielny winner.
wikipedia
2d8487a4ebc9c5202188ce419f330cd354f36f4f
he made his debut for the gunners on
he made his debut for the gunners on 13 september, coming on as an 86th-minute substitute for gervinho in a 1–1 draw away to borussia dortmund in the uefa champions league. on 28 september, he scored his first goal for arsenal in the 2–1 win over olympiacos in the uefa champions league.
wikipedia
11f3e8fe17d074488ba055da3f91f27ae1e67b36
santos later said that he was not deserting
santos later said that he was not deserting a sinking ship by leaving fenerbahçe, insisting he loved playing for them. "i am leaving fenerbahçe from front door", santos told reporters at istanbul airport on 31 august. "i love the country, istanbul and turkish people. i can come back here at the latter stages of my care...
wikipedia
3ed5496c004b5926f14e0d435a6caf430866e444
he scored a total of 10 goals in
he scored a total of 10 goals in 52 league appearances for the football club. he scored 5 goals in 25 appearances in the turkish super league in the 2010–11 season, making him the top scoring left back in turkey. on 29 august 2011, arsenal agreed a €7m fee for the transfer of santos.
wikipedia
ebcf8b4f878f35790642df65af851a4c27d72121
in 2008, santos moved to corinthians, with figueirense
in 2008, santos moved to corinthians, with figueirense retaining 50% economic rights for the future transfer fee. the deal was partially financed by dis esporte, to which corinthians later sold 22.5% of the rights. along with dentinho and renato, for r$ 5.4 million total fee. corinthians also sold 40% rights to turbo s...
wikipedia
f5cad248f1e49aaa8ee1a38c44248e621ec199e1
andré clarindo dos santos (born 8 march 1983)
andré clarindo dos santos (born 8 march 1983) is a brazilian former professional footballer who played as a left-back, but was also utilised as an attacking midfielder or left winger. on 15 june 2009, he made his first international appearance as a substitute in a match against egypt. santos participated and helped bra...
wikipedia
b361cb950a20fb36070346d8773bf11f959cb499
leevi meriläinen is a finnish professional ice hockey
leevi meriläinen is a finnish professional ice hockey goaltender for the belleville senators in the american hockey league (ahl) as a prospect to the ottawa senators of the national hockey league (nhl). meriläinen previously played with the oulun kärpät of the top-tier finnish liiga and major junior hockey with the ont...
wikipedia
82a604c3555d6d7132c30420093b65448f5498d0
meriläinen was invited to ottawa's training camp in
meriläinen was invited to ottawa's training camp in 2023. however, he did not make the team and was assigned to ottawa's echl affiliate, the allen americans, to start the 2023–24 season. meriläinen was re-assigned to belleville on 28 october. with the return of søgaard from the nhl, meriläinen was re-assigned to allen ...
wikipedia
605fa67dde4e842356a266d3995163e36fe3bd57
following the conclusion of oulun kärpät's season, meriläinen
following the conclusion of oulun kärpät's season, meriläinen returned to north america to join ottawa's american hockey league (ahl) affiliate, the belleville senators. he played his first game on 2 april 2023 with belleville against the toronto marlies, posting a 41-save shutout. following the game he was recalled by...
wikipedia
276eee7afe2aa592d97de323c61c3ee1f31d11e9
during the 2022–23 liiga season, meriläinen rejoined oulun
during the 2022–23 liiga season, meriläinen rejoined oulun kärpät and established himself as the starter, having a terrific year with the team. he posted a 2.02 goals against average and a.918 save percentage while setting the league record for most shutouts by a rookie with eight. however, he was injured towards the e...
wikipedia
9ee5f9ce8843a296f9de02ecfc87e69c6bb2b1f2
the senators asked meriläinen if he would join
the senators asked meriläinen if he would join the ontario hockey league (ohl)'s kingston frontenacs for one season. the frontenacs had selected meriläinen in the canadian hockey league 's import draft. he agreed and joined the frontenacs for the 2021–22 ohl season. he experienced mixed results with the frontenacs beco...
wikipedia
245c877f33fc042bb6b52422a7139c1e02d6d8da
meriläinen joined oulun kärpät of finland's top-tier liiga
meriläinen joined oulun kärpät of finland's top-tier liiga as a young player, rising quickly within the team's development ranks. he was with kärpät's under-20 team playing in 22 games and registering.934 save percentage in the 2020–21 season in finland. following his season in finland, he was selected by the ottawa se...
wikipedia
4370641f4039337db33c43669b411fcd53a5b10b
leevi meriläinen (born 13 august 2002) is a
leevi meriläinen (born 13 august 2002) is a finnish professional ice hockey goaltender for the belleville senators in the american hockey league (ahl) as a prospect to the ottawa senators of the national hockey league (nhl). meriläinen previously played with the oulun kärpät of the top-tier finnish liiga and major juni...
wikipedia
349ec2c8b4e5a984dbcc357961b9913a7a2a6bf0
the 2008–09 national division three north was the
the 2008–09 national division three north was the tenth and last season of the fourth division (north) of the english domestic rugby union competition using the name national division three north. the division was set to be re-branded national league 2 north for the following season due to an rfu reshuffle of the entir...
wikipedia
483613c6ac366bfa0394ae5d71a0cb1cb0c3a147
the 2008–09 national division three north was the
lington mowden park who were relegated despite finishing runners up the previous season. darlington mowden park would drop down to the newly named national league 3 north. the second relegated team, halifax, were initial supposed to join darlington mowden park in that division but due to financial difficulties the club...
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72b742bf1cb2b66defa01e900c59430e2280bf8d
nuneaton made it an instant return to the
nuneaton made it an instant return to the (newly named) 2009–10 national league 1 winning the league title and promotion ahead of nearest rivals caldy who finished 9 points behind without the consolation of the usual north-south playoff. at the opposite end of the table halifax suffered their second consecutive relegat...
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e22608c8a961f7fcdf690d1dca7b412f61cbeaec
the 2008–09 national division three north was the
the 2008–09 national division three north was the tenth and last season (twenty-second overall) of the fourth division (north) of the english domestic rugby union competition using the name national division three north. the division was set to be re-branded national league 2 north for the following season due to an rf...
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dd6337aab58de49d55c5800c45ab4531ad3e9755
sodium channel protein type 5 subunit alpha, also
sodium channel protein type 5 subunit alpha, also known as nav1.5 is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. nav1.5 is found primarily in cardiac muscle, where it mediates the fast influx of na+-ions (ina) across the cell membrane, resulting in the fast depolarizati...
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83e06ee503bc13878107eada16833c98d3e63d84
the cardiac sodium channel na 1.5 has long
the cardiac sodium channel na 1.5 has long been a common target in the pharmacologic treatment of arrhythmic events. classically, sodium channel blockers that block the peak sodium current are classified as class i anti-arrhythmic agents and further subdivided in class ia, ib and ic, depending on their ability to chang...
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25d869f2f351e4fb94e2ac373dea57955b5c2944
genetic variations in scn5a, i.e. single nucleotide polymorphisms
genetic variations in scn5a, i.e. single nucleotide polymorphisms (snps) have been described in both coding and non-coding regions of the gene. these variations are typically present at relatively high frequencies within the general population. genome wide association studies (gwas) have used this type of common geneti...
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0f34d8679e0c4c45ea80e15eb0d9209813078081
scn5a mutations are believed to be found in
scn5a mutations are believed to be found in a disproportionate number of people who have irritable bowel syndrome, particularly the constipation-predominant variant (ibs-c). the resulting defect leads to disruption in bowel function, by affecting the nav1.5 channel, in smooth muscle of the colon and pacemaker cells. re...
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ff4ae89c9d853a14a99b8c0514eca487fe2be068
mutations resulting in a gain-of-function are causal for
mutations resulting in a gain-of-function are causal for long qt syndrome type 3 and are also more recently implicated in multifocal ectopic purkinje-related premature contractions (meppc) some gain-of-function mutations are also associated with af and dcm. gain-of-function of na 1.5 is generally reflected by an increa...
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62f7e0f89e5def122a2259d7ecce20b3041280ae
to date, loss-of-function mutations have been associated with
to date, loss-of-function mutations have been associated with brugada syndrome (brs), progressive cardiac conduction disease (lev-lenègre disease), dilated cardiomyopathy (dcm), sick sinus syndrome, and atrial fibrillation.
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a7e42a138070491674796c0baa2c9d84922efbf7
mutations in scn5a, which could result in a
mutations in scn5a, which could result in a loss and/or a gain-of-function of the channel, are associated with a spectrum of cardiac diseases. pathogenic mutations generally exhibit an autosomal dominant inheritance pattern, although compound heterozygote forms of scn5a mutations are also described. also, mutations may...
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7a52b733ca41e035e4b21e5c3083f003a4fa287b
apart from the beta-subunits, other proteins, such as
apart from the beta-subunits, other proteins, such as calmodulin, calmodulin kinase ii δc, ankyrin-g and plakophilin-2, are known to interact and modulate function of na 1.5. some of these have also been linked to genetic and acquired cardiac diseases.
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016e71447051b31859e9fa8bf83b9fac0a986621
trafficking, function and structure of na 1.5 can
trafficking, function and structure of na 1.5 can be affected by the many protein interaction partners that have been identified to date (for an extensive review, see abriel et al. 2010). of these, the 4 sodium channel beta-subunits, encoded by the genes scn1b, scn2b, scn3b and scn4b, form an important category. in gen...
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d94765c0374d8dfb5a16a32f4e5e2d7b3406febd
na 1.5 channels predominantly mediate the sodium current
na 1.5 channels predominantly mediate the sodium current (i) in cardiac cells. i is responsible for the fast upstroke of the action potential, and as such plays a crucial role in impulse propagation through the heart. the conformational state of the channel, which is both voltage and time-dependent, determines whether ...
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48cebc5e84f251d95fd0b2b3a01c178b3dc30ee2
na 1.5 is a large transmembrane protein with
na 1.5 is a large transmembrane protein with 4 repetitive transmembrane domains (di-div), containing 6 transmembrane spanning sections each (s1-s6). the pore region of the channels, through which na+-ions flow, are formed by the segments s5 and s6 of the 4 domains. voltage sensing is mediated by the remaining segments,...
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0dd7f38a7dac1a899806eeb4c4d80e530fa4ca57
more than 10 different splice isoforms have been
more than 10 different splice isoforms have been described for scn5a, of which several harbour different functional properties. in the heart, two isoforms are mainly expressed (ratio 1:2), of which the least predominant one contains an extra glutamine at position 1077 (1077q). moreover, different isoforms are expressed...
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56878ef8f5bdb5252a81ca278db1c7cef8bd6872
scn5a is mainly expressed in the heart, where
scn5a is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. in contrast, expression is low in the sinoatrial node and atrioventricular node. within the heart, a transmural expression gradient from subendocardium to subsepicardium is present, with higher expression o...
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c34ffc44b94c265791e48c5e464b8edbb906831c
scn5a is a highly conserved gene located on
scn5a is a highly conserved gene located on human chromosome 3, where it spans more than 100 kb. the gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5' untranslated region (5’utr) and exon 28 the 3' untranslated region (3’utr) of the rna. scn5a is part of a family of 10 genes that encode differen...
wikipedia
b9061a37d60731aef59dafeedd8f8f978aba0e53
sodium channel protein type 5 subunit alpha, also
sodium channel protein type 5 subunit alpha, also known as na 1.5 is an integral membrane protein and tetrodotoxin -resistant voltage-gated sodium channel subunit. na 1.5 is found primarily in cardiac muscle, where it mediates the fast influx of na -ions (i) across the cell membrane, resulting in the fast depolarizatio...
wikipedia
74194eacc0aa7852c73c658b6f1e7f390d406719
he is an emeritus tutorial fellow in mathematics
he is an emeritus tutorial fellow in mathematics at wadham college, oxford. having taught at wadham since 1986, hodges was elected a fellow in 2007, and was appointed dean of wadham college from the start of the 2011/2012 academic year.
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c0b7cd6b12f7c854844ecd0854b0846436163fa4
alan turing: the enigma formed the basis of
alan turing: the enigma formed the basis of hugh whitemore 's 1986 stage play breaking the code, which was adapted for television in 1996, with derek jacobi as turing. the book was later made into the 2014 film the imitation game directed by morten tyldum, starring benedict cumberbatch as alan turing. the script for th...
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5a5d48ae3d1d701eb9d90f4ef29c059dd3ca177d
hodges is best known as the author of
hodges is best known as the author of alan turing: the enigma, his biography of the british computer pioneer and codebreaker alan turing. the book was critically acclaimed when it was first published in 1983, with donald michie in new scientist calling it "marvellous and faithful". in june 2002 it was chosen by michael...
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19c98e981bdfe9a408e1bd1aeb71b7699b334e5c
andrew philip hodges (/ ˈ h ɒ dʒ
andrew philip hodges (/ ˈ h ɒ dʒ ɪ z / hoj -iz; born 1949) is a british mathematician, author and emeritus senior research fellow at wadham college, oxford.
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ff0a6e375c397e6863d59023e3e3329bacf6b480
magnetic 2d materials or magnetic van der waals
magnetic 2d materials or magnetic van der waals materials are two-dimensional materials that display ordered magnetic properties such as antiferromagnetism or ferromagnetism. after the discovery of graphene in 2004, the family of 2d materials has grown rapidly. there have since been reports of several related materials...
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8a94a794df1d2213c8ab5b8799ff4a6cccf6d7aa
magnetic 2d materials can be used as a
magnetic 2d materials can be used as a part of van der waals heterostructures. they are layered materials consisting of different 2d materials held together by van der waals forces. one example of such structure is a thin insulating/semiconducting layer between layers of 2d magnetic material, producing a magnetic tunne...
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5bb578247564dc7f8e70ed7004523ed3ed4a13e2
to the data. the critical exponents depend on
to the data. the critical exponents depend on the system and its dimensionality, as demonstrated in table 1. therefore, an abrupt change in any of the critical exponents indicates a transition between two models. furthermore, the curie temperature can be measured as a function of number of layers (n {\displaystyle n})....
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5cf43d81802ac41ac43c26b06fbeec237736d120
magnetic properties of two-dimensional materials are usually measured
magnetic properties of two-dimensional materials are usually measured using raman spectroscopy, magneto-optic kerr effect, magnetic circular dichroism or anomalous hall effect techniques. the dimensionality of the system can be determined by measuring the scaling behaviour of magnetization (m {\displaystyle m}), suscep...
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0f837fe2d16a12bf98c4ff8d8d69e49aa193acca
where j {\displaystyle j} is the exchange coupling
where j {\displaystyle j} is the exchange coupling between spins s i {\displaystyle \mathbf {s} _{i}} and s j {\displaystyle \mathbf {s} _{j}}, and a {\displaystyle a} and Λ {\displaystyle \lambda } are on-site and inter-site magnetic anisotropies, respectively. setting a → ± ∞ {\displaystyle a\rightarrow \pm \infty } ...
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c831b173f8a34d7098df59239dc8f18e8c2d0fb5
the 2d ising model describes the behavior of
the 2d ising model describes the behavior of feps, cri. and fe gete, while cr ge te and mnps behaves like isotropic heisenberg model. the intrinsic anisotropy in cri and fe gete is caused by strong spin–orbit coupling, allowing them to remain magnetic down to a monolayer, while cr ge te has only exhibit magnetism as a ...
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927aed4d5f57f5f41e00a7ba85ef7dba5aad5c5a
for 2d systems, the transition temperature depends on
for 2d systems, the transition temperature depends on the spin dimensionality (n {\displaystyle n}). in system with n = 1 {\displaystyle n=1}, the planar spins can be oriented either in or out of plane. a spin dimensionality of two means that the spins are free to point in any direction parallel to the plane. a system ...
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a2e7d25cbc0cee73e5a1f3aed949ef1bfd00ee30
magnetic materials have their (spins) aligned over a
magnetic materials have their (spins) aligned over a macroscopic length scale. alignment of the spins is typically driven by exchange interaction between neighboring spins. while at absolute zero (t = 0 {\displaystyle t=0}) the alignment can always exist, thermal fluctuations misalign magnetic moments at temperatures a...
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