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The TÜV SÜD Safety Gauge Food Segment Report is a detailed industry-specific study investigating the awareness, understanding and importance of food safety issues among consumers and businesses.
The research highlights that the majority of consumers expect safer food products and are willing to pay more for them. Yet despite this expectation, it is concerning that almost 1 in 3 food businesses believes that food safety remains a significant industry-wide issue, given the strict requirements for food and its direct health impact.
Based on these findings, there is an opportunity for businesses to increase food safety by adopting a ‘safety at source’ approach. Download the Safety Gauge Food Segment Report to find out how these latest food safety findings impact your business. | <urn:uuid:b7bb9d89-e47a-4cb2-b0c5-33cb3ecfc8fa> | CC-MAIN-2022-33 | https://www.tuvsud.com/ko-kr/resource-centre/stories/safety-gauge-2017-food | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.92592 | 166 | 1.609375 | 2 |
For this binding, you will need some heavy paper or cardboard, a dull-colored yarn
(such as a dreary gray or muted red), and a black candle.
It is best done during a waning moon, or during the Dark Moon.
Draw and cut-out a basic human shape. When you have the shape cut out, draw
features on it to resemble the person you wish to bind.
You can use markers, crayons, pencils... whatever you feel allfortable using.
Form a mental image of the person as you draw his/her features.
Pay attention to details such as clothing and any particular identifiers such as glasses, scars, etc.
Focus your intent as you draw, concentrating on why you need this person to leave you alone.
When you have the figure allpleted, fold it in half length-wise, with the features turned in.
Light the black candle and sit for a few minutes, holding the folded figure.
Gaze at the candle flame and concentrate on the black candle absorbing all the
negativity this person has caused in your life. If you have hatred or anger for this
person, throw it into the candle and ask that it be taken away.
Now, take the yarn and slowly, with much concentration and visualization, wrap it tightly
around the figure, chanting quietly as suits your needs. Name the image as you chant.
For example, if you wish an abusive ex-spouse to leave you alone, so you might chant:
"You are (person's name).
You have no power over me anymore.
You will leave me alone."
Call on any deities you might have, especially those who are protective, and ask their help.
Build the power with your chanting as you wrap the figure over and over.
When the figure is allpletely wrapped, thrust all your power into it.
Know that this person cannot do harm to you or anyone else.
Hold the bound figure over the candle (but not touching the flame!) and say,
"(Person's name), I bind you in the name of the Lord and Lady.
You can not harm me. You can not harm my family.
You can not harm yourself. You are bound by my will; so mote it be!"
Place the bound figure in a safe place -- perhaps your magical cabinet or at the
bottom of a dresser drawer -- and leave it alone. Know that you are safe from the
negative intentions of the person you have bound. It is done. If necessary,
renew the spell at each full cycling of the Moon by taking the bound figure out
and charging it again over a fresh black candle. | <urn:uuid:29c81f77-88c9-4ef4-84e6-da124cb02a95> | CC-MAIN-2022-33 | https://www.whitemagic.ca/spell/Simple-Binding-Ritual.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573876.92/warc/CC-MAIN-20220820012448-20220820042448-00072.warc.gz | en | 0.947952 | 557 | 1.507813 | 2 |
THE HAGUE – The Restitutions Committee has advised Minister of Education, Culture and Science Jet Bussemaker to restitute to the Jewish owner’s heir two paintings that were sold involuntarily during the Second World War. The Minister has accepted the advice.
The advice concerns the paintings Amsterdam Town Hall by Gerrit Berckheyde (NK 1978), on loan to the Amsterdam Museum, and View of a Dutch Harbour with Figures by Adam Willaerts (NK 2729), on loan to Centraal Museum in Utrecht. Both works belong to the Dutch National Art Collection. These pictures are now in the Netherlands Art Property Collection (NK collection), which consists of artworks returned from Germany after the Second World War.
Until the Second World War they were part of the collection of Jewish art lover Sam Bernhard Levie. He sold the Willaerts painting around 12 September 1940 through a Dutch art dealer to W.A. Hofer, who purchased art on behalf of Hermann Göring. On 15 September 1940 Levie sold the Berckheyde painting to a Dutch art dealer, who in turn sold it to a German museum. During the occupation of the Netherlands Levie and his wife were deported by the Nazis and were killed in Sobibor in May 1943.
In accordance with the policy rules that apply to the NK collection, the Restitutions Committee concludes that there was involuntary loss of possession as a result of the Nazi regime. It therefore advises Minister Bussemaker to return the paintings to the original owner’s heir. The Minister has accepted the advice.
About the Restitutions Committee
The Advisory Committee on the Assessment of Restitution Applications for Items of Cultural Value and the Second World War advises about claims to items of cultural value lost during the Nazi period, also referred to as looted art. Since the Restitutions Committee was established in 2002 it has issued advice on 129 cases and has had 142 claims submitted to it. | <urn:uuid:63a4eb7e-d06e-4770-9504-34cbfcc86c48> | CC-MAIN-2022-33 | https://www.restitutiecommissie.nl/en/news/paintings-returned-to-jewish-art-lover-s-heir/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.971342 | 401 | 2.03125 | 2 |
News•February 2, 2017
The EPA Has Started to Remove Obama-era Information
By Brian Kahn
The Environmental Protection Agency’s website has begun to transform under the Trump administration.
A group of researchers have found what are likely the first steps in a major overhaul of a site that’s been closely watched since President Trump’s inauguration on Jan. 20. Federal climate plans created under former President Obama, tribal assistance programs, and references to international cooperation have been stricken from the site.
A mention of carbon pollution as a cause of climate change has also been removed and adaptation has been emphasized, indicating an attempt to separate the cause of climate change from the response. Some of the changes — like removing mentions to programs and task forces that have run their course as well as broken links — are housekeeping, according to an agency statement.
There have been extensive revisions made to the EPA's climate collaboration page, including removing language about carbon pollution.
Click image to enlarge. Credit: EDGI
Putting the web page changes together with Trump's statements dismissing climate change gives a clearer picture of his vision of “America First.” It likely signals that the U.S. will be stepping back from addressing global climate change. And by removing the information, it could give Trump and Scott Pruitt, his nominee to head the EPA, more leeway to decimate funding for programs they see as incompatible with “America First.”
“If the public is unaware of partnerships depending on the EPA, it may be easier to shrink the EPA without raising as much concern,” said Gretchen Gehrke, a data quality manager at Public Lab and a member of the Environmental Data and Governance Initiative (EDGI).
The changes were shared exclusively with Climate Central by EDGI, a group of scientists tracking federal websites and data. They first noticed the changes on Jan. 22 on a page formerly called “Federal Partner Collaboration,” but now dubbed “EPA Adaptation Collaboration.” Researchers spotted further changes on Jan. 26 to climate and water and international cooperation pages. All the pages are subpages of the EPA’s climate change page.
Obama’s legacy is being wiped away. One common theme running through the alterations is removing references to Obama-era projects such as the Climate Action Plan and other federal roadmaps to address climate change. The international partnership page also lost a paragraph affirming the U.S. commitment to the United Nations climate negotiations.
“They’re mostly scrubbing it of anything that has a hint of Obama,” said Gretchen Goldman, the research director for the Center for Science and Democracy at the Union of Concerned Scientists. “The United Nations stuff being removed is also maybe not surprising but definitely not positive.”
Trump campaigned on a promise to revoke much of Obama’s legacy, including on climate change. He’s made good on that promise at the EPA by nominating Pruitt to head the agency. Pruitt dogged the EPA with lawsuits as Oklahoma’s attorney general and has generally sided with oil and gas interests against environmental protections. Erasing mentions of Obama’s executive orders is another move, albeit one that’s a fairly common practice when the presidency changes hands.
“I am actually surprised to say that none of this strikes me as particularly egregious, but perhaps that is because my expectations are so low,” said Jessica Wentz, a fellow at the Sabin Center for Climate Change Law.
An EPA spokesperson said that all the changes were routine and in line with agency guidelines.
Mentions of local commitments and partnerships have been scaled back. The EPA could also be heading toward a pull back from supporting U.S. communities, including some of the poorest in the country. The updated partners page has removed mentions of the Tribal Environmental General Assistance Program.
That program provided $65.5 million to tribes across the U.S. in 2016 to help increase their ability to prepare for and adapt to climate and other environmental changes. The program requested $96.4 million in the 2017 budget to expand its scope of work.
A tribal assistance program has been removed from the EPA's page on climate collaboration.
Click image to enlarge. Credit: EDGI
While the program still has a standalone web page as well as pages on regional EPA office websites, its disappearance from the partnerships page raises some warning flags about the future of the program.
“I am very concerned about tribal rights under the new administration, and would keenly watch information regarding federal-tribal partnerships,” Gehrke said.
The new web page also includes language that “some” state, local and tribal activities are supported by the EPA, further opening the door to cut back funding and partnership activities.
“That combined with what they’ve already said about scrutinizing grants and contracts doesn’t look good,” Goldman said. “It sends a signal to EPA partners to be on high alert.”
International commitments could be in jeopardy. The EPA site is also missing mentions of the United Nations and the Organization for Economic Cooperation and Development. That includes a paragraph on the EPA’s international partnerships page stating that the U.S. is committed to the international community through the United Nations climate talks.
Language on the EPA's international climate partnership page has removed introductory text about the U.S. commitment to the United Nations climate talk process.
Click image to enlarge. Credit: EDGI
The changes follows a pattern seen on the State Department’s website. After the inauguration, a handful of pages on the U.S. commitment to international climate talks and funds were removed.
Trump has pledged to withdraw from the Paris Agreement and he has taken a transactional view of international relations. That could lead to reduced funding for climate efforts in developing countries in particular.
Recently leaked documents published by BuzzFeed News show newly minted Secretary of State Rex Tillerson is even less committed to the Paris Agreement than his on-camera testimony would bely, further underscoring the possibility of the U.S. stepping back from a burgeoning leadership role on climate.
Climate change is being disassociated from carbon pollution. In the process of removing a mention of Obama’s Climate Action Plan, the partnerships page also no longer mentions carbon pollution as a cause of climate change. Removing the commitment to the United Nations process also came with removing a statement linking greenhouse gas emissions to climate change.
Coupled with new language framing climate change as an adaptation issue, the early changes show that the EPA could continue its climate work but with less of a focus on reining in the underlying cause of climate change.
That’s underscored by a report from InsideEPA, an online news service that monitors the agency, showing that the Trump administration could soon start to remove what it’s deemed as “propaganda” from the EPA site. Given Pruitt’s dim views on the link between climate change and carbon pollution, it’s likely that those references will be in jeopardy.
“Highlighting adaptation is good for us in terms of food security, and even national security, but not coupled with a de-emphasis on our responsibility to reduce greenhouse gas emissions and do everything we can to mitigate the potential change,” Gehrke said.
Gehrke and her group will continue to monitor the EPA website as well as other federal climate sites. She said that EDGI monitors around 25,000 web pages across the government using proprietary software that allows them to track changes to the language and code. As more political appointees start their terms at the EPA and other agencies, there will likely be a lot more to monitor for clues about what comes next for climate policy.
Editor's note: Climate Central is collaborating with EDGI to help make its monitoring of federal websites more widely accessible to researchers, the media, and the public.
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The West’s Largest Coal Plant May Close. It’s a Big Deal. | <urn:uuid:39034bbe-2284-4832-a35a-b8cc500169fc> | CC-MAIN-2022-33 | https://www.climatecentral.org/news/epa-climate-web-pages-change-21133?utm_campaign=buffer&utm_content=bufferface8&utm_medium=social&utm_source=twitter.com | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.94975 | 1,702 | 2.484375 | 2 |
back start next
[start] [ 40 ]
Figure 12.33 Trade sigaals geaerated are displayed with both the familiar dots used oa previous charts as well as the actual oscillator plots.
Chart created with TradeStation® 2000i by Omega Research,Inc.
track successive changes in support or resistance, since these numbers are needed to place accurate trailing stops.
To maintain a reasonable amount of order to this process, I suggest you seriously consider a traders checklist similar to the one shown in Figure 12.34. I have created the checklist in an Excel spreadsheet simply for ease of presentation. Although I find this format useful, other formats could obviously be created.
The first column is used to label each trade with its own identification number. The next column records the major trend of the day as described by the Directional Day Filter (DDF) using a +, -, or 0 for an uptrend, downtrend, or a trendless day, respectively.
The next columns are used to register each oscillator signal as it appears on the chart. PI is used to identify a slow Percent R indication for a trade, while the P2 column confirms a Percent R indication for the trade when the faster setting of the indicator gives its signal. The next four columns are used to track first the slow and then the fast setting of each oscillator as they occur.
Figure 12.34 A simple traders checklist will assist the trader ia processiag the iaformatioa aecessary to geaerate a high-probability trade.
When columns through H are completed, then one immediately examines the chart for an appropriate support or resistance point to be used to place a buy or sell stop. This number is recorded under the appropriate column, either I or J.
As the market continues to trade it is entirely possible that a new support or resistance number will be generated such that you will need to make an adjustment in the placement of the appropriate buy or sell stop. Although it is possible to simply replace the price level representing the old stop level with the new one, I would suggest that you simply use the next lower row to record the new point. This is extremely helpful when you go back to study your trades at the end of the day. If several entries and exits are made, which is often the case with this strategy, it is most helpful to have these support and resistance numbers recorded so that you may easily retrace all of your steps for each trade as they actually occurred. The movement of these stops is probably the hardest thing to re-create at the end of the day when you critique your activities of the previous session.
These same support and resistance columns are used to record both the initial placement of a trailing stop and any changes that may be made as the trade progresses and you move this stop to protect your position prior to liquidation.
Also, you may wish to use the next column to record any order numbers, ticket numbers, and so forth associated with each order placed or each cancel and replace order that occurs as things progress. Recording this information can be very valuable should it
PUTTING IT ALL TOGETHER
become necessary to correct any errors made during order placement and fill reports.
The final columns are used to record actual fill and offset prices when you receive them.
1. Combining the Directional Day Filter with dual settings of the popular oscillator indicators is an effective tool for the identification of high-probability trades in the direction of the major trend of the day.
2. Market-defined support and resistance is useful in the actual placement of buy and sell stops.
3. The same support and resistance tools can be used effectively to establish levels for trailing stops to protect a position and eventually exit the market.
4. A structured four-step method of trade generation can be an effective method for creating high-probability trading signals.
5. A simple, effective traders checklist is a useful tool to aid in the organization of each trade.
DIRECTIONAL DAY FILTER BREAKOUT SYSTEM.
In Chapter 10 covering the Directional Day Filter I briefly mentioned a breakout system that makes use of this simple tool for day trading. In this chapter I will cover the design, customization, and implementation of this system in detail.
Although this approach does use the Directional Day Filter as a setup routine, the system we are going to build here is considered to be a completely different trading method than the one developed previously using the four-step approach to enter in the direction of the major trade of the day. Obviously the two systems can be used together. Just be aware that the two approaches are quite different in their methods.
As discussed earlier, the system is a basic system that trades the breakout of the early intraday range as defined by the Directional Day Filter. If the filter is predicting an uptrend for the rest of the day, the system places a buy stop slightly above the intraday range. If the forecast is for a downtrend, the system places a sell stop slightly below the intraday range.
Although the basic system is about as simple as they come, the effective implementation of this idea in actual trading becomes a bit
more complicated. As with any system or trade, you must decide when and where to enter and when and where to exit. The fine-tuning of these critical decisions will ultimately determine the overall profitability of the system.
There are four basic parameters that must be addressed for this to be an effective system. They are:
1. Time of the breakout.
2. Exit strategy.
3. Stop placement.
4. Stock selection.
In Chapter 3, "People, Prices, Personalities, and Probabilities," there was a brief discussion concerning the different manner in which each particular security or commodity contract responds to various trading parameters. Understanding the response of your favorite stock will be absolutely essential to your success with this system. Each issue responds in its own manner to any system, but particularly to this one. There is significant variance in the time of the breakout and the proper exit strategy among the many issues I have tested with various versions of this breakout system. Later in this chapter there are a series of bar graphs displayed that graphically point out the wide variances of stock issues to selected parameters of this system.
As a general rule, the higher-priced, more volatile issues will respond most favorably to this system. Consider that we are, with this system, attempting to capitalize on quick intraday price moves. The item being traded must exhibit significant price swings to generate the type of movements we are looking for. The quieter, lower-priced issues that are usually confined to relatively narrow, less volatile ranges will not exhibit the types of price changes that are necessary for our system to make profitable entries and exits.
Even within the more volatile, higher-priced stock sectors there will be significant differences among issues that affect the placement of entry and exit stops as well as the determination of profit targets.
I will present as many graphs and statistical tables in this section as is practical in an attempt to present readers with a fully functional, basic day trading system that can be implemented with the basic information you find here. This approach will also fully apprise readers of
the absolute necessity of fully understanding the response of every issue to be traded using this strategy. Although I will present statistical tables and graphs on many of the popularly traded issues, it is not practical to cover every issue that could be effectively traded using this technique. Readers carefully walking through the creation of an effective setup for trading several issues in this chapter will gain the experience necessary to develop a similar strategy for an issue or commodity contract of their choice.
I will first demonstrate a method by which anyone could develop such a system without the aid of sophisticated charting or trading software. I will create the system using basic charting observations and a logical step-by-step method. Keep in mind as we walk through this process that although a computerized system is quite helpful in developing such a trading strategy it is entirely possible to do so with a pencil, a lot of paper, and good, black coffee. Chapter 14 will cover the basics of automated system development and testing.
I have selected charts of QLogic Corp. (QLGC) for the security to be used to demonstrate the adaptation of this system. This issue is actively traded, with an average daily volume of 2.65 million shares traded over the last six months of 2000. Its volatility is well suited to this system, its range has been fairly consistent over the testing period, and there have been no recent splits to skew the data. Obviously this is not a recommendation for readers to buy or sell this issue. This is simply the issue I have chosen to demonstrate the process of developing a trading system from the Directional Day Filter data. There are multiple issues that can be effectively traded using this strategy.
STEP ONE: SET BREAKOUT TIME
The first critical issue to address when implementing this system is the timing of the critical breakout. We must determine with the greatest degree of accuracy possible the time of day when the breakout strategy is to be implemented to be the most effective.
The first step is to analyze as much data as possible, testing each practical time frame for the percentage of days during which, after this time frame, a breakout occurred on only one side of the current intraday range.
[start] [ 40 ] | <urn:uuid:645de37e-12c9-42d5-9bc1-0123bc48bc3e> | CC-MAIN-2022-33 | http://eng.yax.su/finlab/ir006/40/index.shtml | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.933456 | 2,245 | 1.75 | 2 |
The title of this post will most likely strike the reader as nonsensical. The canon of Graeco-Roman art, populated with statues of athletes, friezes of battles, a Pompeian fresco or two of dancing fauns, seems to leave no space for abstraction. Most of us think of classical art as uniformly figurative, and we perceive this mimetic tradition as unbroken until the nineteenth century, when experimental figures like J. M. W. Turner begin to display an ever-lesser interest in the minute reproduction of the visually perceptible world.
The likes of Wassily Kandinsky and Kazimir Malevich, it is commonly thought, deal the final blow to the formerly unchallenged tradition of representational art as they start to paint pure abstractions, art bearing no trace of reference to anything recognizable. This straightforward narrative of linear development is challenged in a striking story told by Pliny in his Natural History. In a fascinating anecdote, surprisingly little-known given the extraordinary evidence it presents, Pliny introduces us to the world’s first abstract painting, composed by the celebrated painters Apelles and Protogenes in the fourth century BC.
The story goes as follows. Apelles, the most accomplished painter of all time according to Pliny, once visited the studio of the likewise respected Protogenes, curious to see the works he had so far only heard rumors of. He found nobody there except an old slave and an empty canvas ready for painting. Instead of telling the slave to inform Protogenes of his arrival, Apelles simply drew an exquisitely fine line on the empty canvas and left. When Protogenes returned and examined the line, he instantly knew that Apelles had been there, as only he could have drawn something that perfect.
In reply, Protogenes drew an even finer line in different color upon the previous one and went out again. Soon, Apelles returned and found himself surpassed in Protogenes’ reply. He took up another color and drew an even finer, barely discernible line upon the previous two, leaving no space for anything more delicate to be executed, and left. At this point, Protogenes conceded defeat and went out in search of Apelles to finally make his acquaintance. Left behind in the studio was a piece of abstract art.
So far, there is nothing exceptional in this story. The Natural History is full of such more or less believable anecdotes of artistic dexterity. Pliny, marvelling at the extraordinary verisimilitude in the finest examples of realist painting, relates how horses would neigh when confronted with Apelles’ painting of a horse, and how birds would peck at Zeuxis’ likeness of grapes. Apelles’ Pollock-like technique of throwing a wet sponge at his canvas to create the effect of foam sounds more unorthodox, yet ultimately results in a meticulously realistic reproduction of the recognizable world as well.
Apelles’ and Protogenes’ painting makes no such attempt at mimesis. This would still be nothing surprising in a mere display of artistic skill, and so far the story has not suggested that the painters perceived their competition as anything more. But in a tantalizing twist at the end, Pliny recounts how Apelles and Protogenes thought it appropriate to treat this exercise as a finished work of art, and how it was displayed to an admiring and appreciative public, even only recently at the Imperial palace on the Palatine:
Among the most elaborate works it had all the appearance of a blank space; and yet by that very fact it attracted the notice of everyone, and was held in higher estimation than any other painting there.audio … [tabulam] spatiose nihil aliud continentem quam lineas visum effugientes, inter egregia multorum opera inani similem et eo ipso allicientem omnique opere nobiliorem.
Naturalis Historia 35.36.83
Although the fame of the artists and the virtuosity manifest in the minuteness of the lines must have contributed to the painting’s charm, these features were not of most interest to the ancient audience according to Pliny. It was rather the very emptiness of the painting that was admired, and it was its very blankness that earned it the estimation as the finest piece of art in the exquisite Imperial collection. The abstract composition was clearly perceived as art. The three solitary lines were weighed with reference to the surrounding figurative pieces and chosen as the finest among them. The spectators perceived the abstract, non-representational piece as capable of giving the same kind of aesthetic pleasure as the figurative art they were used to, and they even found the pleasure derived from contemplating this absence of presence in some way superior. For a modern reader, this anecdote conjures up the extraordinary image of ancient Romans crowding around and admiring a minimalist abstract painting, oblivious of the surrounding portraits of gods and goddesses.
Unsurprisingly, the story of Apelles and Protogenes’ experiment did not gain particular traction with early modern artists. Its oddity and simplicity provided little opportunity for opulent classicising compositions and were for a long time overshadowed by tales such as Apelles’ painting and falling in love with Alexander’s mistress Campaspe, subject of numerous renaissance and baroque nudes. One may expect a sudden surge of interest in the anecdote to appear with the emergence of abstract art, yet it does not seem to have resonated with early avantgardists except Guillaume Apollinaire.
In a short 1912 article, Apollinaire writes on the elusiveness of the subject in cubist art and calls this absence of representation ‘pure painting’, providing admirers with ‘artistic sensations due exclusively to the harmony of lights and shades and independent of the subject depicted in the picture’. He finds a precedent of such practice in the piece by Apelles and Protogenes, yet nevertheless calls cubism ‘an entirely new plastic art’, apparently uninterested in tracing continuities and eager to portray the avantgarde as a revolutionary breakthrough.
Apollinaire was right in not ascribing too much weight to Pliny’s story and treating it as nothing more than a fascinating curiosity. The painting by Apelles and Protogenes was an isolated case rather than an example of a flourishing abstract tradition in ancient Greek art. The fame of the artists and the ancient admiration of finesse must have been pivotal in enabling this extraordinary, one-off abstract exhibition.
Yet this does not mean that we should not take the story seriously. Rather, it can serve as a reminder that simplistic, traditionalist narratives often overlook the most fascinating details, in the case of art history negating the variety and diversity of artistic expression. Western artbooks skimp over the striking impressionism of Song Dynasty splashed-ink paintings, preceding Turner’s first works by over half a millennium. Women like Georgiana Houghton and Hilma af Klint painted pure abstractions before Kandinsky and Malevich but still gain little recognition for their work. Just so, visitors to the Imperial palace were capable of enjoying ‘artistic sensations due exclusively to the harmony of lights and shades’ long before the first cubist exhibition.
Alex Tadel is a recent graduate from an MSt in Greek and Latin Languages and Literature at the University of Oxford. Stationed in Ljubljana, Slovenia, she is taking a short break from academia and working as a freelance writer, researcher and tutor. | <urn:uuid:5fcb4248-1964-4d2c-ad50-29aff068415b> | CC-MAIN-2022-33 | https://sententiaeantiquae.com/2020/11/20/ancient-greek-abstract-art/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572221.38/warc/CC-MAIN-20220816060335-20220816090335-00072.warc.gz | en | 0.955868 | 1,573 | 3.140625 | 3 |
Forgiveness is more than just speaking the words. It must be sincere and from the heart. It must be patterned after the forgiveness God has granted to us. It must be accompanied by actions which befit true forgiveness.
Forgiveness involves a kind attitude all animosity and hatred. All bitterness, anger, abandoning – wrath, clamor and evil speaking should be put away (Eph. 4:31). We can hold no grudges. One must deny the impulse to get even and seek to do the forgiven one good.
Forgiveness involves forgetting (Heb. 8:12), but what does it mean to forget? It is impossible for a person to completely obliterate the wrong from his mind. Rather it means to not hold the person accountable for it anymore. When forgiveness is granted that should end the matter. It should never again be dredged up or held against the one who.
has been forgiven.
Forgiveness should be given by the “golden rule” (Matt. 7:12). One should always be willing to forgive– even at repeated offenses. Matthew 18:21-22 has the apostle Peter asking, “Lord, how often shall my brother sin against me, and I forgive him? Up to seven times?’ Jesus said to him, ‘I do not say to you, up to seven times, but up to seventy times seven. | <urn:uuid:595afebd-4196-450b-bdcd-863ad04cee1a> | CC-MAIN-2022-33 | https://grovelandchurchofchrist.com/what-it-means-to-forgive-by-gene-taylor/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.949608 | 290 | 2.703125 | 3 |
The COVID-19 pandemic has seen an increase in rhetoric blaming China for the outbreak of the virus and anti-Asian hate crimes. Some members of DePaul’s Asian Pacific Islander Desi American (APIDA) community have also noticed racism towards their community becoming more rampant — citing instances of hearing COVID-19 referred to as the “Chinese virus” and “kung flu.”
“There has been a lot of hate directed towards APIDA folks during this pandemic and so I feel like now especially, is the time to try to build, strengthen and care for the community,” junior Tuyet Anh Le said.
Because of these sentiments, members of DePaul’s APIDA community are using APIDA Heritage Month, celebrated in May, to promote public awareness of their histories and uplift one another through solidarity. The tradition continues despite stay-at-home orders and COVID-19 safety measures, but it looks different this year — festivities had to transition online.
APIDA Heritage Month is the brainchild of Jeanie Jew, a congressional staffer in the mid-1970s. Jew expressed frustration after witnessing the 1976 U.S. Bicentennial celebrations that lacked recognition of Asian American contributions. Jew then approached Frank Horton, former New York representative, and sought a national observance similar to Black History and Hispanic Heritage Month.
Jew thought of the holiday as a way to solidify and celebrate Asian Americans as members of American society and acknowledge their significant contributions. Five decades later, the APIDA community still draws inspiration from these sentiments and champions similar causes like representation and recognition.
May was specifically chosen to acknowledge two significant events in the history of Asian Americans. On May 7, 1843, the first Japanese immigrants came to the United States, and May 10, 1869, marked the completion of the first transcontinental railroad, which was pioneered by Chinese immigrants.
In 1992, the holiday was expanded from a week to an entire month to commemorate past and current struggles of the APIDA community, pay tribute to activists and trailblazers, and recognize triumphs of fighting for representation across political, academic and entertainment sectors.
DePaul’s APIDA members said this memorialization comes after decades’ worth of labor and hardship – citing alienation caused by the Chinese Exclusion Act of 1882, internment of Japanese Americans during World War II and the ongoing plight of indigenous folks to keep their lands and sovereignties.
Every year, DePaul’s APIDA Heritage Month celebration is themed. Last year, Eva Long, the university’s APIDA Center coordinator, and her team chose “Occupying Space, Reclaiming our APIDA Identity.” This year, the theme is “Amplify.”
“The leadership team of the APIDA Cultural Center [thinks this theme] encompasses the realities, emotions and spirits of the APIDA community at DePaul,” Long said.
Long reveals that she finds the “Amplify” theme fitting particularly because of experiences in the past few months. Long said the APIDA community experienced “two incidents of cultural appropriation” since the beginning of 2020 — making it critical to amplify APIDA voices.
In February, APIDA Sisterhood Uprising (ASU), a student club for APIDA-identifying women, transgender and nonbinary individuals, wrote a petition directed to DePaul’s head of Campus Recreation, who spearheads DePaul Men’s Ultimate Club (DUC). According to the petition, the team had “used a part of Japanese culture as an aesthetic to profit off of [Japanese culture], literally selling the hats [and jerseys] to the general public for $23,” which ASU found appropriative.
Earlier this year, the sporting team showcased its new designs by posting them on its public Instagram account. The design showed the word ‘duck’ in katakana, a Japanese alphabet, to represent its acronym DUC.
To combat these experiences, which they felt to be appropriative, Le mobilized ASU, a club she co-founded with Caroline Yu.
“The culture that the team has ‘bonded’ over and love so much, is the same culture that tore so many Japanese diaspora families apart during World War II internment of Japanese people,” the petition read. “This culture … is currently being erased and taken away from the actual Japanese diaspora.”
A week after releasing the petition and gaining 566 signatures, DUC revoked its merchandise. DUC said in a statement that they decided to revoke the uniforms after seeing the petition.
“We saw that our uniform had hurt and offended the APIDA community at DePaul and that was not our intention,” the statement read. “…We recognize the mistake we made and are grateful to have learned from this experience.”
DUC also sent an apology letter to ASU.
“What the university was not ready for was how the APIDA community disrupted notions of the model-minority myth and organized each other and the greater university community,” Long said. “[We’ve taken] a stance against racism and appropriation and demanded action.”
The global pandemic and this incident didn’t stop the APIDA community from celebrating APIDA Heritage Month. Although they couldn’t physically gather to commemorate their achievements and advocate for their struggles through protests like they had done in past years, they held events via Zoom, like many other DePaul groups.
Long, alongside the Office of Multicultural Student Success, has been planning for months to welcome educators, activists and artists to help kick off the celebration.
Although plans had to change quickly after events were moved online, they still carried on.
“We knew we had to pivot many of our programmings and opportunities of engagement online,” Long said. “[This is] to provide rich virtual events that honor the story, resilience and history of the diasporic APIDA community.”
To support the larger APIDA community, Long and her team also collected a series of free events happening from coast to coast throughout May and shared them with students through their newsletter and social media. This included watching the inaugural PBS docu-series Asian Americans, using Netflix Watch Party to recognize pivotal moments of APIDA representation, sharing meals together like a mukbang and contributing art to a collective zine.
Sophomore Geri Palillo is grateful for the accessibility of these events. Palillo is on the executive board for DePaul’s Asian Cultural Exchange (ACE) and DePaul’s first ever Philippine student association, KALAHI, meaning “of the same lineage” in Filipino. Through these roles, she helps in creating and maintaining spaces for APIDA students to meet and collaborate.
“I try my best to be aware and attend the online events,” Palillo said. “If I can’t go, I’ll share the details for others that may be interested.”
Palillo is used to thinking outside the box to meet remotely. KALAHI hosted a Zoom cooking class where attendees learned how to make the Filipino dish chicken and vegetarian adobo.
Le, a certified supporter of the APIDA Cultural Center, said she felt nostalgic about past events.
“I remember attending all of the different workshops that the center hosted last year including the APIDA Heritage Month: Grace Lee Boggs Brunch,” Le said. “That event was so special and fun because it was a gathering to recognize APIDA students at DePaul and the legacy of Grace Lee Boggs.”
The brunch recognizes the work of Boggs, a Chinese American activist, writer and APIDA icon, primarily known for spending much of her life advocating for civil and labor rights. The brunch is organized to bring members of the DePaul community to celebrate APIDA activists (like Boggs) and initiate conversation about contemporary relevant issues.
Despite being in the stay-at-home order, Long and her team wanted to push through with this annual tradition. This year, like everything else, the brunch took place via Zoom instead of Cortelyou Commons.
Celebrating online hasn’t come without its challenges. As all types of programming transitioned online, Le has found it more taxing to stay plugged in and engaged.
“In my personal experience, it’s been harder doing it over Zoom because I have to put in a lot of social and even physical labor to be in front of a screen for hours,” Le said. “It’s also more awkward because you can barely pick up on social cues and accidentally interrupt people while talking.”
Being an APIDA student leader, Le also finds it harder to disseminate information about her club’s events. Nowadays, she resorts to texting and sending emails, when before she would just bump into her members at the APIDA Cultural Center and invite them in person.
Although there are challenges to celebrating this year, Le appreciates the efforts of the APIDA Cultural Center.
“I think it is cool to see all the programming going on,” Le said. “At least we have the opportunity to engage if we want as compared to being alone in isolation.”
As an effort to contribute, Le hosted DePaul’s most recent CHA(I) Time on May 28 to close off APIDA Heritage Month through a virtual open mic poetry reading.
The center launched CHA(I) Time when remote learning started. The event aims to center human connections and community care while practicing social distancing. The quarter-long series has ranged in events such as a Desi makeup tutorial, learning a K-pop dance choreography, playing an Asian American edition of Quiplash and discussing how to prepare for Ramadan.
Le is proud of her community’s active participation and resilience.
“ASU worked really hard this past quarter in organizing around issues that were impacting our community,” Le said. “We care for and love each other, honor and learn about our histories, hold space for each other and fight for our own community with other communities.”
The fight continues in light of COVID-19.
Mansi Kathuria, senior organizer at Asian Americans Advancing Justice-Chicago, hopes that individuals see an increase in racism as a call to organize and are taking action.
Kathuria added that although Asian American communities are being uniquely impacted by the xenophobia of this particular moment, all low-income individuals, essential workers and communities of color are being devastated by the pandemic.
“The bare minimum is pushing back when you hear anti-Asian and anti-Chinese sentiments,” Kathuria said. “[Be] an active bystander if you notice somebody experiencing anything from a microaggression to a hate crime in public.”
Header Image by Jessica Nalupta, 14 East | <urn:uuid:fd9d9778-bd8d-49e3-bba5-44e048a55de7> | CC-MAIN-2022-33 | https://fourteeneastmag.com/index.php/2020/05/29/celebrating-apida-heritage-month-may-be-more-vital-than-ever/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.95663 | 2,308 | 3.09375 | 3 |
Current Petrol Price Per Litre
Petrol Price in Tamil Nadu : Sales of diesel and petrol increased 6.6%, and 4% respectively in the month of October, over last year as the country celebrated festivals and the economy revived backs to tracks. After the onslaught of the pandemic, the sales of diesel observed first monthly rise. The complete lockdown stalled the demand for diesel; the transportation fuel. When the data is compared to that of September the effect is more dramatic; the rise of the market of diesel is 27.5%, and that of petrol is 8.5%. Tamil Nadu today petrol price is also witnessing the same trend. The state-run leading oil marketing companies provide these statistics.
Cost of petrol in Tamil Nadu today is INR84.62 per liter as on today. As the economy is recovering, the price of jet fuel also witnessed an increase of 13% rise on a month to month basis, but still below 50% compared to last year. Consumer demand increase during the festive season and goods transpiration also enhanced to meet the growing demands. The demand for two-wheelers and cars also started picking up, propelling the fuel price. Petrol price in Tamil Nadu is also increasing aligning with the overall economic improvement. With more economic activities and normalcy returning, demand for fuel is rising. Petrol price in Tamil Nadu is witnessing a surge in the festive season and expected to continue to year-end.
More people prefer private transport than the public one; to avoid contamination of pandemic is also boosting Petrol Price in Tamil Nadu Today. Recovery in demand for petrol and diesel has improved capacity utilization of refineries. The capacity utilization of Indian oil has enhanced 94%, which was below 50% in April.
Refining of Crude Oil
In petroleum refineries crude oil is transformed into petroleum products which can be used as fuel in transportation, generating heat, electricity and building blocks to manufacture chemicals. Petroleum refiners are intricate, expensive factory facilities, where crude oil is broken down into various components, and then selectively reconfigured into new products. Separation, Conversion and Treatment are the three necessary steps of refiningof crude oil. The cost of refining of crude is included in the Petrol rates in Tamil Nadu or Petrol aajkabhav in Tamil Nadu. | <urn:uuid:e1e4697d-e80d-4132-b0d8-3c1c6ba0962b> | CC-MAIN-2022-33 | https://www.mandibhavtoday.com/tamil-nadu-petrol-rate/21/ps | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.954386 | 493 | 1.617188 | 2 |
Capex Verses Opex: Making budgeting easier in uncertain times
Brexit took most people by surprise, but now the news has sunk in, it is time to start thinking about what this means for small business. Shortly after the country voted and the pound sunk, major hardware manufacturers Dell and HP announced price hikes on computer hardware. This trend is set to continue in the New Year. Deciding what to spend money on lies at the heart of success for many businesses and it’s something that IT directors and CFOs everywhere are having to come to grips with.
What do we mean by capex and opex?
Capex stands for capital expenditure and it involves the money you spend on things like buildings, machinery and other facilities. Operational expenditure, or opex, is the money you spend on things like the day to day running costs such as wages, utilities and repairs.
How capex and opex figure in IT support
In the past, Directors favoured capital expenditure when it came to IT infrastructure because they have control of how it is gradually paid off and can keep track of the depreciation over time. It works when you have a clear idea what your company needs for the future and are certain that the outlay is going to be worth it and effective.
With the development of technologies like the cloud, however, more and more CFOs are beginning to take a more operational expenditure approach, opting for managed support and technical consultancy delivered remotely. Seeing IT as opex rather than capex means that you no longer need to invest in the infrastructure but can pay for it on an ongoing basis as you would with any other utility.
The benefit of IT as capex
The one real benefit that comes with buying your own IT infrastructure is that, at some point, you get to own it. The problem nowadays is that technology is changing rapidly and businesses need to keep up with the latest developments if they are going to compete. Seeing IT as a capital expenditure is becoming ‘old fashioned’ particularly for small to medium size businesses looking to expand.
The benefit of IT as opex and managed IT support
The debate over capex and opex in IT is really something of a red herring. The real issue is whether organisations should be investing in IT infrastructure, along with the costs of employing the people to maintain it, or outsourcing it to a third party supplier. It’s a question of money yes, but also a matter of which provides the best service.
The money issue is one of making a substantial payment for installation and maintenance over having your IT supplied on a bespoke basis without taking on site responsibility. What happens when your IT infrastructure suddenly becomes out of date? Is your IT team up to the job? Is it better to have a technical consultancy?
Treating IT as an operational expense has several advantages:
- It can be tailored to your needs.
- You pay a monthly cost that is lower than the overall initial expenditure in having a server installed.
- You get access to the latest technology and security systems.
- It can grow and change as your business grows.
- Capital is freed up because it isn’t earmarked for a big project.
The truth is that technology has now developed to such an extent that IT can be effectively supplied remotely.
The Ratcliff IT team are here to make everything just work for you at a budget you can manage. We take the time to evaluate your business IT infrastructure, tailor provision to your current needs and help your grow more efficiently. | <urn:uuid:d672b0ec-8b7c-40fe-afee-5bff6ad28ed4> | CC-MAIN-2022-33 | https://www.ratcliff.it/news/capex-verses-opex-making-budgeting-easier-uncertain-times | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.969994 | 725 | 1.710938 | 2 |
Being named as a trustee is an important role. Trustees have certain legal duties that they must fulfill, in addition to adhering to the terms of the trust agreement. Even though the trustee has the right to manage trust assets, and the discretion to administer the assets reasonably, the trustee is also bound by certain fiduciary obligations to the trust beneficiaries. A California trust administration attorney can help you review qualifications for a trustee. If you are a trustee, an attorney can answer questions you might have regarding your duties and responsibilities as a trustee.
Duties and Responsibilities of Trustees in California
The trust document itself dictates many of the trustee’s duties and responsibilities. However, trustees are also bound by the duties outlined in the California Probate Code under the Trust Administration section.
Some of the duties and responsibilities outlined in the code include:
- The code requires a trustee to administer the trust in the best interests of the trust beneficiaries.
- A trustee of a revocable trust should follow the written directions of the settlor or someone appointed by the settlor to give the trustee directions. An exception may be if the written directions modify the trust. In that case, the trustee does not need to follow the directions unless they follow the procedures outlined in the trust for modifying the terms of the trust.
- A trustee must treat multiple beneficiaries fairly and impartially when dealing with the beneficiaries and managing the trust property.
- A trustee cannot use or destroy trust property for the trustee’s benefit.
- Trustees cannot require beneficiaries to release the trustee from liability as a condition of making disbursements from the trust.
- A trustee should take reasonable steps to enforce claims that are part of the trust, avoid accepting roles that are adverse to the trust and defend actions that could harm the trust assets.
The most important role of a trustee is to serve as a fiduciary. As a fiduciary, the trustee must always act in the best interest of the trust beneficiaries. That duty typically guides all other duties and responsibilities of the trustee. A trustee should also maintain the trust assets separate and apart from all of his or her other property, and maintain detailed, current, and accurate books and records for the trust. Beneficiaries may request an accounting of the trust assets periodically. The trustee may have a duty to provide the accounting, depending on the terms of the trust and other factors.
Trustees also have a duty not to delegate their responsibilities and duties to another party when the trustee is reasonably able to perform the duties. This requirement does not prohibit a trustee from employing professionals, such as attorneys, accountants, financial advisors or property managers, when necessary to assist with the administration of the trust.
The type of trust can dictate some of the trustee’s duties and responsibilities. A trustee should always read the trust document in full to ensure the trustee understands the duties and responsibilities outlined within the trust document.
Contact a California Estate-Planning Attorney For Help
Trustees may consult with a California estate planning attorney when they have questions regarding their duties and responsibilities. They may retain the services of an attorney when they need assistance with various legal matters that impact the trust. Talk with our California estate planning attorneys today. | <urn:uuid:2922e70e-7854-407f-8635-dd95e6127f69> | CC-MAIN-2022-33 | https://loewlawgroup.com/2019/11/14/what-are-california-trustees-responsible-for/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.946566 | 657 | 1.679688 | 2 |
When analyzing investment decisions, we did not consider in any detail the largest investment decisions that most firms make, i.e., their acquisitions of other firms. Boeing’s largest investment of the last decade was not a new commercial aircraft but its acquisition of McDonnell Douglas in 1996. At the time of the acquisition, Boeing's managers were optimistic about the merger, claiming that it would create substantial value for the stockholders of both firms. What are the principles that govern acquisitions? Should they be judged differently from other investments?
By Prof. Aswath Damodaran | <urn:uuid:5da3b1c1-a967-4261-8e3e-6ac1e70742f6> | CC-MAIN-2022-33 | https://www.performancetrading.it/Documents/AdValuing/AdV_Index.htm | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.96848 | 117 | 1.773438 | 2 |
St. Paul’s Bay
When the layout of the little seaside resort of Clacton on Sea was projected, 150 years ago, no provision was made for a church. By 1874, however, J. H. Page of Thorrowgoods Farm was planning development of his land to the east, as far as Victoria Road; for some time the eastern limit of the Marine Parade. It was in one of these new streets he generously offered a site for the erection of Clacton’s first church. A committee was immediately formed, designs were prepared by G. Gard Pye of Colchester, the architect of some of the town’s earliest buildings, and in August a tender of £88 was accepted.
On 16th June 1875 St. Paul’s was opened for worship, and on 15th August 1878 it was consecrated by the Bishop of St. Albans as Clacton was then in his diocese. It had cost, altogether, £1,250 and was built of concrete; for a time standing alone in the fields. Its dedication no doubt recalled the early association of Clacton with St. Paul’s Cathedral as, in ancient times the kingdom of the East Saxons included London as well as the present county of Essex, and the whole area was in the diocese of London with St. Paul’s as the cathedral church.
The ecclesiastical parish was formed in December 1878 and covered the area likely to be developed. Boundary stones were placed at the north end of Pier Avenue and in Holland Road, opposite Victoria Road but these were later removed although one was later salvaged and preserved in St. Paul’s church. There was repeated criticism, however, that the church was too remote from the town centre, so in 1888 a corrugated iron mission hall was built in the High Street; the hall was destroyed by fire five years later and replaced.
Although enlarged in 1881 the church soon proved too small for the growing town, and even after St. James’s parish was formed in 1907, on the western side of town, it was still inadequate. A new church was proposed and a building fund started but owing to the war and increasing costs it was not until January 1965 that the present St. Paul’s was started.
Designed by G. H. B and Roy Gould the new building proved to be light and attractive, in complete contrast to the old Victorian church. A stone was laid by Sir John Ruggles Brise, H. M. Lord Lieutenant of Essex, on 12th June 1965, and the building was consecrated by the Bishop of Chelmsford on 15th July 1966. | <urn:uuid:f7dc9c96-16a6-4d77-88c8-2b4e7dceff96> | CC-MAIN-2022-33 | https://www.tendringdc.gov.uk/leisure/clacton-150/sign-9-st-paul%E2%80%99s-bay | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.993667 | 557 | 2.40625 | 2 |
On 26 April 2022, the Court of Justice of the EU (CJEU) rendered a ruling in joined cases C-368/20 NW v Landespolizeidirektion Steiermark and C-369/20 NW v Bezirkshauptmannschaft Leibnitz stating that Member States of the European Union (EU) can re-introduce border controls within the Schengen Zone only under strict conditions. The Court has stepped up as a guardian of the Treaties protecting free movement of people without controls at the internal borders of the EU as “one of the major achievements of European integration” (para 65 and 74). At the same time, the Court has left some aspects of the application of these strict new rules unclear, leaving room for the European and national executives to exercise their function and fill in the blanks.
Border controls between Schengen Member States
Six Schengen countries, namely Germany, France, Austria, Denmark, Norway and Sweden, have reintroduced border controls over the past years for national security reasons (see a full list, including those introduced during the Covid-19 pandemic). The Schengen Zone is supposed to be an area without internal borders. Border controls can only exceptionally be re-introduced and even then, such re-introductions should be temporary. The abolishment and re-introduction of border controls are regulated in the Schengen Borders Code (SBC). Austria has had border controls on its southern borders to Hungary and Slovenia de facto continuously since September 2015 (until November 2021 at the time of these proceedings). They have been re-introduced 14 times based on five different articles of the SBC (para 26).
The applicant, an Austrian national, has been subject to border controls at the Austrian border when entering from Slovenia on two occasions, on 29 August and 16 November 2019, and refused to show an identity card or passport when asked by the border guards. Being more than an informed citizen, the applicant, who works otherwise as an EU and international law scholar, asked expressly whether the officers were conducting an identity check or a border control and obtained a confirmation that this was an instance of a border control. The applicant challenged both border controls as well as the imposed fine of 36 Euros before an administrative court, which decided to refer preliminary ruling questions to the Court in Luxembourg on 5 August 2020.
In the public and political debates, the re-introduction of border controls within the Schengen Zone was not meant to target the EU citizens returning from their summer holiday, but rather individuals who are unlikely to bring legal proceedings: third-country nationals who have irregularly crossed the Schengen external borders or alleged criminals who are hiding from the law enforcement. The case has been one of high political salience due to the tension between, on the one hand, the sovereignty arguments invoked by the Member States regarding their national security and, on the other hand, the importance of a Schengen Zone without internal borders in the bigger project of European integration, complementing the EU internal market and citizenship.
The political salience of the case was reflected in the judicial proceedings in Luxembourg (see our previous blog post) and the case was assigned to the Grand Chamber by the CJEU President. In the oral hearings in June 2021, apart from the Austrian government, three other governments presented their views as intervening parties (Germany, France and Denmark). It was clear that, due to the erga omnes effects of preliminary rulings of the CJEU, their respective practices of border controls would also be affected by the judgment.
Strict judicial interpretation of the exceptions to the area without internal borders
In its ruling, the Court clearly sides with the applicant and the European Commission confirming that the SBC should be interpreted as prohibiting border controls such as those in place in Austria. While the Court engages carefully with the arguments of the Member States, it does not cite the Advocate General Opinion (discussed in our previous blogpost) even a single time.
The Court focusses on the first of the three questions referred by the national court, asking whether Article 25(4) SBC allows for the reintroduction of border controls that exceed the maximum total duration of six months. The judgment revolves around three points: 1) which time limits are applicable to the reintroduction of border controls based on Article 25 SBC? 2) what circumstances allow for their reintroduction? 3) Can Member States directly rely on Article 72 TFEU to reintroduce border controls?
An absolute six-month limit
When considering the applicable time limits, the Court sets out by finding that the very wording of Article 25(4) SBC indicates that such limit is six months, as opposed to the two-years limit in Article 29 SBC, and that is it absolute.
Several elements from the legislative context corroborate this conclusion: the system of time limits set out in the SBC is clear and precise. It encompasses the initial reintroduction of border controls, their prolongation in case of a persisting threat, and their total duration which, again, ‘shall not exceed six months’. A legislative gap seems implausible in such a tight system.
Teleological interpretation leads to the same result. The Court sees the SBC as part of the broader framework balancing free movement of persons, public policy and national security (Article 3(2) TEU, Article 67(2) TFEU, see also Staatssecretaris van Justitie en Veiligheid). The possibility for Member States to reintroduce border controls must therefore be considered an exception. Free movement of persons is one of the ‘main achievements of the European Union’ (para 65) and exceptions to it should be interpreted strictly (recital 27 SBC, see also Kempf and Jipa). A laxer interpretation, allowing border controls based on the same threat to extend beyond six months would result in a potentially unlimited reintroduction, jeopardizing this achievement (para 66).
When is a threat a new threat?
The second point concerns the question of what constitutes a ‘new threat’. This is crucial, because a new threat allows for an ex-novo application of the time limits. The Court remains vague on the specific substantive criteria distinguishing new from persisting threats, possibly granting discretion to the executive in this regard. It does, however, establish that Member States should provide sufficient information on why the circumstances represent a new threat and thus allow for external scrutiny of such a decision when they express the intention to reintroduce or prolong Article 25 border controls (para 81).
National security exceptions in primary EU law
The last point addressed in detail by the Court is the possibility for Member States to directly invoke primary law, namely Article 72 TFEU, to justify a derogation from the SBC. Germany argued that the ‘migration crisis’ constituted a situation unforeseen by the SBC and invoked the national security exceptions enshrined in primary EU law. The Court acknowledges that Member States retain their responsibility to ensure national security but recalls that this should not result in an exemption from compliance with EU law (Ministrstvo za obrambo). The cases in which Member States can rely on primary EU law, including Article 72 TFEU, in order to derogate from secondary EU law must be interpreted strictly (Commission v Hungary). The SBC framework is all but insensitive to the needs of public security, already seeking to balance free movement and public security concerns (para 88). The Court refuses the idea of ‘exceptional exceptions’ that Member States could call upon.
The Court’s final words are of reproach. The Commission, especially, remained silent when Member States notified it of the intention to reintroduce border controls. However, when forced to take a stance in these proceedings, brought by an individual applicant, it deemed such border controls unnecessary and disproportionate (para 91). The SBC confers upon the Commission clear oversight powers (Article 27(4)), which it should exercise by issuing opinions and engaging with Member States politically. A word of caution is also directed at the Member States, which are expected to exchange information, consult each other, and cooperate as provided in Article 27 SCB to ensure that the balance between free movement and public security is maintained. While the Court clearly steps up to enforce the SBC against the Commission’s and the Member State’s reluctance, it also signals what spaces remain open for political actors on both the EU and the national level to intervene. Those include the definition of what constitutes a new threat and the exact criteria for national measures’ proportionality (para 71).
Remaining uncertainties: What next?
At least three uncertainties remain after this ruling of the CJEU:
In principle, all border controls currently in place in the Schengen Area should be perceived as contrary to EU law. As already foreseen by the Court itself (para 82), if we apply the conditions set out by the CJEU based on Articles 25 and 29 SBC, we can expect that the referring court will declare the border controls in force in Austria in 2019 outside of the allowed exceptions. As a preliminary ruling, this case clarifies the interpretation of the exceptions in the SBC for the entire EU. The same reasoning would therefore apply, without much doubt, to all the internal border controls currently in place. In their current practices, Member States have not provided any significant material (studies, statistics or reasoning) to justify the existence of a new threat.
While the situation is relatively clear-cut as a matter of principle, it is unclear how this could be implemented in practice following this ruling. The Commission could feel empowered to take up again its role as guardian of the Treaties and enforce this strict interpretation of the SBC exceptions vis-à-vis Austria and the other Member States. It could be an example of a mutual empowerment of the Commission and the CJEU in EU law enforcement. Otherwise, the ruling could be enforced on a case by case basis before national courts in the respective Member States. We can then also expect that some national courts that have granted a lot of deference to the national executive, such as the French Council of State, would need to adjust their reasoning to integrate the CJEU arguments.
A second uncertainty concerns the legality of new border controls in the future in the Schengen Area. The Austrian, German and Danish authorities have been rather careful in commenting on the consequences of the judgment. The national administrations are exploring the leeway left by the Court’s ruling. And the Court has left quite some margin for the Member States to argue, this time within the parameters of EU law, the proportionality of border controls as well as the existence of a new threat that could justify their re-introduction. These gaps could be filled by the Commission, the national courts or the CJEU in future rulings. An incremental development of a line of case law on the legality of re-introduction seems likely. It remains open whether it will develop along the lines of this judgment and emphasize that the exceptions to the rule of open borders within Schengen have to be interpreted narrowly. The CJEU has probably not said its last word yet.
The third uncertainty concerns the implications of this ruling for other areas of EU law. In its judgment, the Court does not emphasize the special character of the Area Freedom Security and Justice (AFSJ), which has traditionally been a rather intergovernmental policy area. This seems to suggest that its interpretation of Member States’ national security is not particular to this domain of EU law. The Court emphasizes that invoking national security does not give the national governments a carte blanche in terms of EU law (para. 84). National security exceptions are relevant also in other areas of EU law. Data protection law provides a recent prominent example (Quadrature du Net (2020)). Moreover, the Court does not respond to the applicant’s argument about a possible violation of the Citizens’ Rights Directive. The Court emphasizes instead that border controls within Schengen should remain exceptional, “irrespective of the nationality” of the person (para 63). It therefore remains unclear whether a reasoning based on free movement of EU citizens would also be possible.
In the joined cases C-368/20 NW v Landespolizeidirektion Steiermark and C-369/20 NW v Bezirkshauptmannschaft Leibnitz, the Grand Chamber of the CJEU takes a very principled stance on the abolishment of internal border controls within the Schengen Zone. Member States have made clear legal commitments to an area without internal borders, which the Court upholds. In light of those commitments, it interprets the exceptions strictly, confirming the absolute nature of the six-month limit for the reintroduction of border controls. This judgment puts pressure on the EU’s political institutions to end the current discrepancies between law and state practice, by either enforcing or reforming the existing legal framework. | <urn:uuid:dbd67bc4-35f5-4d69-9a0e-bb342bff49d6> | CC-MAIN-2022-33 | https://verfassungsblog.de/schengen-restored/?replytocom=830630 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.934001 | 2,668 | 1.75 | 2 |
Sir Richard Branson leads the charge in race to save rhinos
By Jamie Joseph
South Africa is home to the majority of the remaining surviving rhinos, and was home to me until I immigrated to New Zealand in 2009. But then a couple years ago the call of the wild brought me back, and I have returned to my motherland to join the last stand in the race to save rhinos from extinction.
These magnificent prehistoric animals have roamed planet earth for more than 50 million years, and they are impervious to almost anything but a bullet. Every one of us that wants to see an end to the genocide of such an iconic species has a role to play in Africa’s poaching crisis, no matter what postal code we belong to. My words are my weapon, and every tourist that goes on safari is a deterrent to poachers, and every person on social media that shares stories that matter are another vital drop in the wave of change. And then there is the star power of the celebrity activists.
I work closely with WildAid, global leaders in wildlife parts demand reduction campaigns, and I am a regular contributor to Virgin Unite. Last month WildAid Ambassador Sir Richard Branson hosted a dinner gala in Vietnam, the main consumer market for the illegal rhino horn trade, alongside China.
Photo credit: Wildaid Vietnam
Branson spends a few weeks a year at his eco conscious Ulusaba Game Reserve, which borders Kruger National Park – the dominant battlefield in this war on rhino poaching, and has witnessed firsthand both the beauty and the carnage. Says the environmental entrepreneur, “A little while back I saw a rhino that had been shot and butchered by poachers, and it’s a devastating image that is permanently etched into my mind.”
While in Vietnam The Virgin Group Founder met with some of the nation’s top business leaders as part of WildAid’s Stop Using Rhino Horn campaign, which aims to stamp out the myths of rhino horn’s medicinal benefits, of which there are none, as rhino horn is nothing but keratin – the stuff in your fingernails. Veiled malicious marketing campaigns are driven by criminals and pro rhino horn trade lobbyists, pushing the black market price up to US$100 000 per kilo, more than gold and cocaine. And as ridiculous as it sounds, owning rhino horn is also considered a status symbol among wealthy elite in Vietnam.
In Ho Chi Minh City, Branson hosted an intimate dinner organized by several non-governmental organizations including WildAid, African Wildlife Foundation, Wildlife Conservation Society and CHANGE, and in collaboration with Virgin Unite, Nhip Cau Dau Tu magazine and The Reverie Saigon. During the event, business leaders signed a pledge in which they committed to never buy, use or gift rhino horn.
Says Sir Richard Branson, “Listening to 25 of the country’s leading entrepreneurs around the table, it is promising to hear that the issue has already become part of a national conversation which is bringing shame to a country of 90 million people entering the global market space. The wheels of politics turn slowly, coupled with a lack of interest in conservation, but the younger Vietnamese do not want to be associated with this vile trade, and here lies an opportunity for mobilization.”
Lifting a lesson from history, between 1970 and 1993 the black rhino population was almost completely wiped out in the previous poaching crisis. Taiwan, once the biggest consumer of rhino horn, isn’t even on the map anymore as a result of education, demand reduction campaigns and strict domestic laws.
Photo credit: WildAid Ambassadors Sir Richard Branson and Yao Ming
In addition to reducing consumer demand for rhino horn in Vietnam, the business leaders discussed the importance of persuading South Africa not to push for the legalization of the rhino horn trade, as some have proposed.
Explains the WildAid ambassador, “We need to make conservation and protection of rhinos more valuable than the sale of their horns. Legalising the rhino horn trade would only cause the demand to skyrocket, sending out an immoral message that the product actually works. This legal market would then become a front for the illegal market, and the incessant poaching will drive the tourism industry into disarray, costing Africa millions of jobs in the next decade, and fuelling more poverty and conflict.”
Poachers killed a record 1 215 rhinos in South Africa last year, and nearly 1000 rhinos have already been poached thus far in 2015, as opposed to 13 in 2007.
But back in Africa, apathy and corruption is permeating every level of law enforcement, and often the people put in charge to protect our natural heritage are the ones causing the most harm. Even if we do crush the demand, what happens if a new market emerges a decade from now?
Rhino poaching is exploiting Africans living in poverty – fathers and sons living near wildlife areas are being recruited by global wildlife trafficking syndicates to poach rhinos, risking their lives for very little financial gain. All the while Asian king pins are building empires by gambling on extinction.
My current mission, ‘solving poverty saves wildlife’, presents solutions to Africa’s poaching crisis, and produces a rolling narrative of successful community conservation stories and blueprints that can scale. Over the past few months while travelling through Zimbabwe, Zambia and South Africa, I have seen with my own eyes that when rural Africans are empowered to be guardians of their natural heritage through meaningful employment poaching literally collapses.
As Sir Richard Branson so urgently points out, “There is a real need for the international community to step up and help these African countries build the capacity to effectively monitor and protect animal populations.Education is power, and the only way to educate is by raising awareness. Both in Africa and globally, we need a lot more people to take action and make a positive impact, before it’s too late.”
Photo credit: Jamie Joseph / Saving the Wild
Photo: Thula Thula 24/7 Rhino Security
Photo credit: Jamie Joseph / Saving the Wild
I am currently on assignment at Thula Thula Game Reserve, in Zululand, South Africa. This breathtaking wilderness was founded by Francoise Malby-Anthony and her late husband, maverick conservationist Lawrence Anthony, whose adventures included negotiating with war lords in Garamba National Park in 2006 in a valiant effort to save the last handful of northern white rhinos.
A groundbreaking partnership has been formed between Thula Thula and the neighbouring Zulu chiefs and their communities, who have since gifted 1000 hectares of land and infrastructure, and out of this was born the urgently needed Fundimvelo Thula Thula rhino orphanage. Seed funding was granted by international animal welfare organization Four Paws, and the upkeep of the rhino orphanage is maintained through public donations. Protected by 24/7 armed security, the orphanage is a sanctuary for traumatised calves that have witnessed their mothers being shot and sliced. And with just 20 000 rhinos left in the wild, every individual rhino is vital to ensure that sufficient animals are protected to safeguard the genetic viability of the species.
Baby orphan Impi is now four months, and was discovered by his mother’s side, drenched in her blood and body fluids six days after she was killed. His left hip was severely stiff and his right eye bulged out, possibly a knock from poachers when he tried to intervene. Not having a horn is what saved him from certain death. He’s still not over it, and sometimes cries, but after a few weeks of enduring love, and around the clock care from his human foster mums, he is becoming curious and affectionate.
I watch these little fat buttocked unicorns playing in their back yard, and I have so much gratitude for the people that go to great lengths to keep them safe. In about two years time these orphans will be released back into the wild and I have to believe that by then the rhino poaching crisis will be behind us, because Africa without its amazing animals is an Africa without soul.
The race is on to save the greatest fairytale on earth.
Photo credit: Thula Thula | <urn:uuid:44fbeab2-af40-405c-bb81-1011d749fbf4> | CC-MAIN-2022-33 | https://www.savingthewild.com/news/sir-richard-branson-leads-the-charge-in-race-to-save-rhinos/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.95213 | 1,709 | 1.773438 | 2 |
April 15, 2018 Share 0 Tweet Share 0 Learning to shoot with a flashlight is one of the most useful survival and self-defense skills a person could have. Statistics show that most self-defense shootings and incidents happen in low-light conditions. A flashlight can help you identify the target and be certain of what you’re shooting at. First and foremost, choose a light model based on your needs and preferences. Once you choose a flashlight, you have to learn how to use it for self-defense. There are some important tactics that you can easily implement to ensure your safety. For example, it’s crucial that you always keep it in the same place, on your belt, and inside your home. Don’t mount your light on a weapon Though this could be convenient and useful at times, it’s not always the best idea. You see, if you were to hear a bump or noise in your house, you want to first check what is making the noise. You don’t want to investigate what’s making a noise with a weapon-mounted light. Why? Well, you don’t yet know where the noise came from. What if it’s your child or your pet? I’m sure you don’t want to point your gun at them, or accidentally pull the trigger. For this reason, you should never aim and shoot a gun unless it is absolutely necessary. I strongly suggest you have a flashlight that’s separate from the one that’s mounted to your handgun. Now you’re probably wondering: How do I Shoot While Using a Flashlight? Before reading any further, please note that should you plan to use any type of weapon, that you seek the advice of a professional or expert first. With that said, there are several different techniques you can choose from. Some of them allow you to point a gun along with your light. Others have your light away from your body. The choice of the technique you’d use is up to you and what you’re comfortable with. I suggest not to bring your gun hand and your light hand together until you’ve decided to shoot. However, make sure to train before you do this because our instincts can sometimes play a big role. Be careful If you do decide to use a gun and a flashlight at the same time, I suggest you drop the flashlight before shooting. This will free your support hand that is holding the light and allow you to hold your gun properly. Still, practice doing this because it’s harder than it sounds. Yes, we understand it’s unnatural for people to drop stuff we’re holding, especially in stressful situations. In this case, I suggest you use a survival flashlight because these are usually durable and drop-resistant. Here are some of the best ways to use a light while shooting: FBI Technique This is quite a smart technique that makes sense, and feels more natural. The idea is to keep the light away from your vital areas. A would-be attacker might want to shoot at your light thinking that’s where you are. Hold the light away from your body with your non-shooting hand. This way you can search for your target without really giving away the center of your location. Still, remember that once you do shoot, the muzzle blast will give it away. Also, you might find it hard to shoot with only one hand. The technique may sound easy, but having your arm extended away from your body can mess up your balance and shooting ability to some extent. Neck Index Technique This is not as tiring, and it’s definitely more stable. Simply, hold the flashlight using an icepick grip again, but against your cheek or neck. Is it more stable? Yes. Is it slightly more dangerous? Also, yes, if the would-be attacker decides to shoot at the light. However, this method allows you to transition from searching to shooting. You can shoot with one hand, holding your flashlight in another. If you find you have time, transition to two-handed techniques. Still, holding the light that close to your body will illuminate you just as well as your target. Keep that in mind. The Harries Technique For this technique, lock the backsides of your hands or wrists together. This will apply some pressure to the backside of your shooting hand and provide a somewhat stable shooting platform. This is the type of technique that requires some practice to do quickly. During stress situations, you can easily get confused about which hand goes where. Ideally, you should point the weapon at the target with one hand, and then slip the support hand under your shooting arm. What you can do is also go from a Neck Index technique, check out the target and then transition to the Harries technique. With just a little practice, this is easy to master. Surefire Technique For this, you need a small flashlight with an On button at the tail-end of the handle. Hold the flashlight between the index and middle finger of your shooting hand with the On switch against your palm. Use a two-handed grip to hold the gun but only with the bottom two fingers of the non-shooting hand. The index, middle finger, and thumb should hold the flashlight. Simply squeeze the flashlight against the palm of your hand to turn it on. Some people point the light to the ground, which is actually a fairly good idea. The ground will reflect just enough light to illuminate the area around you. The downside is that the technique is that because it is not easy, it takes time to master. You’ll have to learn to operate the light with only three fingers and use the rest to support the gun. Unless you’re trained to do this, you’ll end up pointing your gun right where you point the flashlight, which is not a good idea. It’s an efficient method but requires training and the ability to shoot within a second. What is the best method? There is no correct answer to this question. In reality, these are all effective, but you’ll have to put in some work to learn how to use them. Some are more complicated than others, but it all comes down to your preference and skills. It’s important you’re careful at all times, regardless of the technique you choose. Whenever there’s low light, shooting guns becomes more dangerous. Admittedly, all these techniques can end badly unless you practice them. Unload your gun and give yourself time to master the techniques safely. Pay attention to your natural tendencies, and what would be the easiest method to use. Also, choose your gun and flashlight carefully since those are what plays the main role. Real-life scenarios may not play out exactly how you practice, but practice does make a great difference. Using a flashlight while shooting means you’d have to hold on to two objects, possibly shoot at a target, and all that while your own life is maybe in danger. Looking for the Right Flashlight? This, too, is a matter of preference. If you can’t make up your mind, I suggest you try a basic tactical flashlight. These models are easy to use, durable and reliable. You may think smaller lights are easier to operate, but those provide less power, which is why I wouldn’t suggest them. Go for a tactical, or even a simple EDC flashlight will do. They are bigger but you’ll quickly get a hold of them with some practice. | <urn:uuid:dc450938-8b7f-4309-aebc-a9f5b1149ebe> | CC-MAIN-2022-33 | https://offthegridguru.com/how-to-shoot-while-using-a-flashlight/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573399.40/warc/CC-MAIN-20220818185216-20220818215216-00072.warc.gz | en | 0.94933 | 1,544 | 2.265625 | 2 |
Turmeric is among those superfoods that has actually taken the all-natural health and wellness globe by storm. While many people may utilize this spice to include taste to curries, health fanatics use turmeric for its lots of purported health and wellness benefits. Just a few of the studied benefits consist of supporting a healthy body immune system, supporting muscle and also joint health and wellness as well as sustaining healthy and balanced cognitive function.Turmeric Curcumin Plus Ingredients
This made me begin to consider how I can begin to experience several of the benefits of turmeric extract Because of turmeric extract’s buzz, you can get your fix of turmeric in numerous forms. I’m a big follower of turmeric’s researched advantages – not its scent or taste. Lathering myself in turmeric soap or having a turmeric-ginger tea wasn’t precisely my favorite in itself, however that’s not way too much of a problem when I learned that supplemented turmeric may really be more reliable than raw turmeric. Hear me out.Turmeric Curcumin Plus Ingredients
Turmeric Plus Reviews
Just how supplemented turmeric beats raw turmeric extract.Turmeric Curcumin Plus Ingredients
There are conditions in which it is far better to take in nutrients through supplements over entire food resources. While uncommon, extracted turmeric extract is among these one-of-a-kind scenarios.
The concentration of curcuminoids can be stronger in supplements compared to raw turmeric extract. While curcumin usually comprises 2 – 8 % of turmeric extract, the curcumin extract in turmeric supplements usually consist of 95% curcuminoids. ¹ Because of the low source of curcumins in turmeric, you will have a hard time to check the wellness benefits of turmeric by merely spraying it on your food.
Moreover, one research showed that cooking turmeric extract may lead to the loss of the curcumin substance. Boiling turmeric for 20 mins was found to be one of the most destructive, suggesting that your turmeric curry or slow chef becomes much less as well as much less advantageous.
Several turmeric supplements likewise consist of some type of peppercorn. The factor for this is curcumin is complicated to absorb on its own. Nonetheless, when paired with peppercorn, there can be a 20-fold increase in bioavailability contrasted to turmeric utilized alone. Some copyrighted types of pepper essence have been particularly established for this objective. Turmeric Curcumin Plus Ingredients
Selecting in between turmeric supplements.
When choosing between turmeric capsules, a worrying number of supplements were made overseas or were Genetically Modified Microorganisms – GMO. I do not understand about you, however I agree to pay added for a supplement that is manufactured in the US and also is non-GMO.
An additional thing I would search for is the presence of organic or non-organic turmeric extract. I understand the process of identifying an active ingredient as natural is pretty rigorous. For a component to be labeled as organic, it needs to be generated without genetic modification or GMOs. Organic turmeric root is a fair bit pricier, which is why it is fairly uncommon to discover a budget-friendly supplement with organic turmeric.
Surprisingly, some turmeric supplements weren’t vegan – I discover this pretty shocking considering the vital components are plant based! This is largely as a result of the capsules being made from gelatin. While I’m not vegan, I can see the benefit of keeping supplements as plant-based as feasible as well as preventing unnecessary damage caused by jelly pills.
There were likewise some encouraging soft gel options, however none of these had natural turmeric and lots of had a long checklist of fillers. Soft gels are in some cases vegan, however usually contain gelatin. If possible, I would go with turmeric supplements in a vegan-friendly vegetable pill.
Considering every one of this, I uncovered VitaPost Turmeric Curcumin Plus. Vegan pleasant, 1500mg of natural turmeric extract, and also a solid concentration of curcumin, make this my turmeric supplement of selection.
VitaPost Turmeric Extract Curcumin Plus is a nutritional supplement including BioPerine and turmeric removes. A big perk is the formula was made to be taken pleasure in by lots of people. It is vegan friendly, gluten cost-free, sugar cost-free and also non-GMO.Turmeric Curcumin Plus Ingredients
Benefits of VitaPost Turmeric Extract Curcumin Plus.Turmeric Curcumin Plus Ingredients
You may be wondering that must take into consideration turmeric supplements. The great aspect of Turmeric Curcumin Plus is that practically anybody can take advantage of supplementing turmeric extract. Everybody can take advantage of antioxidant support in some form as well as turmeric extract is extensively tolerated. That being said, constantly speak with a health care expert prior to taking any type of dietary supplement – that includes this one.
I would certainly be specifically careful if you are expecting. Big amounts of curcumin taken during pregnancy might alter the levels of estrogen in the body. The ramifications for this on pregnancy aren’t worth it in my opinion, nevertheless I am not a doctor and also would certainly suggest consulting yours before making any type of choices.Turmeric Curcumin Plus Ingredients
The Science of Life + The Seasoning of Life.
Ayurveda is just one of the world’s oldest all natural recovery systems. In Sanskrit, Ayurveda indicates “The Science of Life.” Stemming from India, it adheres to the concept of advertising healthiness as opposed to fighting condition.
Turmeric extract has actually been utilized for centuries in Ayurveda practices to promote healthiness. It is thought to have several advantageous homes as well as is frequently recommended as a treatment in a paste form. Possibly the large range of presumed advantages can be linked to modern scientific research’s findings that this root has solid antioxidant buildings.
Something I locate fascinating is that the principle of bioavailability boosting originates from Ayurveda. As a matter of fact, the term ‘bioavailability booster’ was first created by researchers in India, that uncovered and clinically validated piperine as the world’s very first bioavailability enhancer in 1976. ⁶ Piperine is, you thought it, the bioavailability booster that Turmeric Curcumin Plus makes use of.
The formula for VitaPost Turmeric extract Curcumin makes use of several of the methods from Ayurveda that have been medically verified to combine the science of life with the seasoning of life.Turmeric Curcumin Plus Ingredients
Just How does Turmeric extract Curcumin Plus function?
Turmeric Curcumin Plus is a combination of three vital ingredients; natural turmeric extract, curcumin, and also BioPerine (piperine). Allow’s study just how these 3 active ingredients work together to form Turmeric extract Curcumin Plus.
Ingredients. Turmeric Curcumin Plus Ingredients
It would not be right to discuss a turmeric supplement without mentioning the turmeric initial. This golden superfood has been utilized in Ayurveda wellness techniques for thousands of years. Modern medication is only just catching up to the Ayurveda techniques, with many researches showing promising wellness advantages.
The major clinical targets of turmeric are the digestive system organs. Some research studies have actually revealed appealing results when turmeric extract is utilized for the intestinal tracts, bowel, as well as colon.
Turmeric extract is widely known for providing potent antioxidant assistance. While most of turmeric’s benefits can be connected to its curcuminoids, the judgment is still out on whether turmeric or curcumin is better for your health and wellness. Extra study is needed prior to researchers can wrap up whether one is much better than the other. That claimed, I would try to take the closest form to the food (turmeric extract) as feasible. I can see why the Turmeric Curcumin Plus formula consists of 1200mg of organic turmeric and also 100mg of turmeric with 95% curcuminoids.
On that particular note, let’s explore what is so unique about curcumin.
A great deal of the research right into turmeric swiftly disperses to curcuminoids and their advantages. Researches suggest that curcuminoids additionally sustain the immune system, cognitive function, and also joint health.
Curcuminoids are taken into consideration to be natural antioxidants. It is this strong antioxidant effect that can sustain joint and also muscle health and wellness by dealing with free-radicals as well as oxidation.
Much like ginger, curcumin also makes a special appearance around Christmas time. While we wouldn’t suggest exchanging your gingerbread men with turmeric cookies right now, I can definitely see the benefit of supplementing turmeric to sustain the immune system and your body’s antioxidant possibility. This body immune system support likewise better bolsters curcumin’s joint and muscular tissue assistance.
One more encouraging benefit of curcumin is the potential to sustain healthy mind function. Several research studies have linked taking curcumin daily with healthy and balanced cognitive function. The factor for this is believed to be curcumin’s antioxidant capacity. One tiny study showed prospective to support a healthy mindset as well as decrease feelings of tension.
Probably curcumin’s biggest flaw is exactly how difficult it is to soak up on its own. No matter how many tablespoons of curcumin you eat if hardly any of the nutrients are being taken in.
Remember when I discussed that turmeric is ideal fortified with pepper? Well, meet the pepper! BioPerine (known chemically as piperine) is the most well-known black pepper remove. This trademarked remove’s history tells the story of its success, with over two decades of being utilized as a bioavailability enhancer.
When BioPerine is taken with curcumin, there can be a 20-fold rise in bioavailability compared to curcumin alone. That would’ve thought that a black pepper extract could be so powerful?
To understand the power of incorporating these active ingredients, it assists to know a bit regarding how the body soaks up nutrients. Nevertheless, it’s not about what you eat, however what you absorb.
When you eat actual food, you’re not simply consuming solitary nutrients, however instead a whole range of substances (minerals, vitamins, enzymes and also various other rewards). These compounds interact to allow the body to harness the most effective results. When one substance is isolated – like curcumin from turmeric – it is not likely to be utilized by the body similarly. Scientific agreement presently stands that you take advantage of all the parts of the root, just the means nature meant.
There are numerous helpful substances within the turmeric root besides the curcuminoids. This consists of the unstable oils, sesquiterpenes, fragrant components, and also roots. The unpredictable oils have shown possible in supporting turmeric’s immune assistance results. ¹³ In addition, the BioPerine of Turmeric Curcumin Plus unlocks the turmeric’s benefits in a manner that the raw root alone can refrain from doing.
Offering Size and Warns.Turmeric Curcumin Plus Ingredients
Turmeric Curcumin Plus consists of 60 stunning orange capsules in every container, comparable to a one-month supply. Take two daily 20-30 minutes before a meal. I ‘d say the size of the capsules are easy to swallow for most people.
A few minutes after opening the bottle you will be welcomed with a warm turmeric scent. As turmeric has a solid aroma, I ‘d be worried by any kind of turmeric supplements that don’t have a turmeric smell (except for maybe soft gels).
Remember that I am not a signed up diet professional or medical professional. I am just your typical person with the time to examine. Constantly talk with your health care professional before utilizing any type of dietary supplement.Turmeric Curcumin Plus Ingredients
Allow’s reach the root of it.
Completely, Turmeric Curcumin Plus seems like an excellent choice for anyone taking into consideration a turmeric supplement. It’s not the cheapest supplement on the marketplace, however in exchange for being non-GMO, made in the United States, as well as consisting of organic turmeric extract, I would certainly claim it is well worth it.Turmeric Curcumin Plus Ingredients | <urn:uuid:8ad6b5a7-abdf-43f3-9fe4-968ec9de2fcf> | CC-MAIN-2022-33 | https://ordinaryandawesome.com/turmeric-curcumin-plus-ingredients-a-2021-review/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.949236 | 2,637 | 1.773438 | 2 |
[MUST READ] Europe must reduce gas consumption now, warns IEA
Russia/Europe locked in economic war of attrition ($WSJ)
Texas deploys power grid emergency measures ($BBG)¹
Hebei’s efforts to reverse groundwater depletion (trans.)
¹ Power grid managers in Texas and elsewhere have a variety of tools to cope with an imminent emergency caused by insufficient generation, including orders to generators for “maximum generation” (mandating output from individual units above their normal recommended operating levels); “no touch” (prohibiting all but critical maintenance and repairs to enable maximum generation and transmission); “reliability must-run” (requiring and paying units to run regardless of their normal economics); and “system-to-system” mutual aid (requesting maximum imports from neighbouring networks). The isolated nature of the Texas grid restricts STS opportunities for ERCOT but it is frequently used in other networks. On the demand side, grid managers can invoke voluntary demand reduction contracts, issue public appeals for conservation, order voltage reductions (usually in two stages), and in the final resort use forcible disconnection, loading shedding and rotating blackouts.
LONDON temperatures have started to ramp towards a likely record on Monday and Tuesday, as the heat builds over southeast England, with each day’s temperature profile hotter the last:
U.S. CRUDE oil inventories around the NYMEX WTI delivery point at Cushing in Oklahoma stand at just 21.6 million bbl, the lowest seasonal level since 2014 and before that 2008, when front-month WTI prices were at $122 and $170 respectively adjusted for inflation:
IF YOU would like to receive best in energy and my research notes every day, you can add your email to the circulation list here: https://eepurl.com/dxTcl1 | <urn:uuid:528f2cb1-de77-4ef5-a41a-e09f95a558ec> | CC-MAIN-2022-33 | https://jkempenergy.com/2022/07/18/best-in-energy-18-july-2022/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.916273 | 389 | 1.703125 | 2 |
Since December, teenagers across Germany inspired by the 16-year-old Thunberg's climate fight have been marching weekly instead of sitting in classes. (AFP)
Thousands of German youths went on strike from school on Friday, joining Swedish teen activist Greta Thunberg who has taken her protest against climate change to Berlin.
Armed with homemade posters bearing slogans like "It's getting hot in here" or "Our house is on fire" or "You're never too small to make a difference", the teenagers packed into a park in central Berlin to sound the alarm about global warming.
From the park in front of the economy ministry, they were to march to Brandenburg Gate, where Thunberg is due to address the crowd.
Police said they have dispatched 300 officers to the protest which is expected to draw around 15,000 people.
"We're going to continue skipping classes every Friday because we can't keep going like that with the climate. We have to pull the emergency brakes," vowed Franziska Wessel, one of the organisers of the protests in Berlin.
Since December, teenagers across Germany inspired by the 16-year-old Thunberg's climate fight have been marching weekly instead of sitting in classes.
With the protests coming at a time when a government commission recommended that coal be phased out by 2038, the youths have seized on the theme to demand a halt to the polluting fuel by 2030.
The youth engagement has left politicians divided on how to react.
Economy Minister Peter Altmaier has urged students not to skip school saying that demonstrations are not less effective outside class hours.
But Chancellor Angela Merkel has welcomed their fight. | <urn:uuid:56261089-161e-4c49-b0e9-fc91749877a0> | CC-MAIN-2022-33 | https://english.ahram.org.eg/NewsContent/2/9/329064/World/International/Thousands-of-German-teens-join-Thunbergs-climate-f.aspx | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.96884 | 346 | 2.09375 | 2 |
Business Compliance as a service is an important aspect in running and maintaining a legal business. It’s an important part of doing business for most business owners. Many companies are now focused on the law, so understanding what business compliance actually means is crucial to maintaining your company in good standing with the authorities. Business compliance refers to a business following all of the laws and regulations pertaining to their staff, their product, and their treatment toward their customers. There are many different types of business compliance; it all depends on the kind of business that you run and how it operates.
Corporate Compliance refers to following all of the laws,
regulations, and rules meant to protect the public from harm from corporations or businesses. The most common laws that are related to corporate compliance include the Fair Labor Standards Act, Sarbanes Oxley Act, Administrative Procedure Act, and Regulation by Organizing Companies. Each of these laws has specific aspects that differ from one state to another, but the overall message is basically the same. Businesses must follow all laws meant to protect the public, and if they don’t comply, then they could be sued. Some states have additional laws meant to protect whistleblowers, but again, every state is unique. This is why corporate compliance is so extremely important.
One way to ensure that you comply with all applicable laws and regulations is to hire an attorney who specializes in business compliance. While you may feel that you can handle all of the necessary paperwork on your own, you are putting yourself at risk for mistakes and lawsuits. This could set you back financially and put you out of business. If you choose to go this route, make sure you get help from a professional.
There are many aspects to business compliance, and it covers everything from food and drink sales to accounting to sexual harassment. There are even regulations for how businesses interact with their customers, including mandatory anti-harassment policies and a long list of rules for what restaurants must serve and how they must clean up their restaurants. All of these laws were designed to promote good customer service and to ensure that businesses operate according to the rules of the community.
Businesses have to follow all laws and regulations,
but there are some that directly affect them. For instance, food and drink sales are required to be done according to the health department guidelines, but it doesn’t matter if you are compliant or not. If you are found to be selling alcohol, it can result in criminal charges and fines. Likewise, if you are found to be not following food hygiene regulations, this can lead to criminal charges as well.
When you talk about the health benefits of business compliance, you have to understand the differences between health and safety regulations. Health and safety regulations aren’t only about preventing food and water from being contaminated but also protecting employees from harmful chemicals and toxins on the job. Many health and safety regulations also apply to workers’ compensation and workers’ compensation benefits. Businesses have to follow these regulations in order to stay in compliance with the law, but small businesses don’t have to worry about things like workers compensation claims and health benefits. These regulations are for large corporations and other large businesses, not for small businesses that are considered family businesses. Therefore, compliance with regulations doesn’t have anything to do with health and safety, but is rather about business operations.
- In addition to the health benefits, business owners need to follow compliance laws in order to keep their businesses operating and profitable.
- Some regulations can require businesses to install alarms and video surveillance, for instance.
Others might require businesses to post signs in all their windows notifying customers that they are smoking inside.
- Business compliance officers will often visit businesses before any new regulations are to be put into place in order to ensure they comply with the new laws.
Businesses need to make sure they are fully compliant with any regulations and not simply adhere to the minimum standards set by the government and state agencies. There are many regulations to follow and without following and complying with all regulations a business owner can find their business shut down. Businesses can avoid shutdowns by taking a proactive approach to regulation compliance. They need to be proactive and work with state agencies, county and local governments, as well as OSHA, to make sure their business is operating in accordance with the law. Businesses can also avoid fines by making sure they inform each other and their employees of their company’s regulations. | <urn:uuid:b748498c-44d2-4f9c-b589-9e9fa2635567> | CC-MAIN-2022-33 | https://www.rapidchargenetwork.com/electric-cars/health-and-safety-compliance-for-small-businesses/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.975368 | 902 | 2.625 | 3 |
This is the start of Agriculture Safety Week in Canada. The week is a reminder to farmers to make sure that they are practicing safe farming protocols. As Micah Quinn explains, a farmer from Mossleigh in Southern Alberta says new farming technology allows his farm to stay safe.
After graduating from Mount Royal University in Calgary with a Broadcasting Diploma, Micah made the trek down to Lethbridge to work for Bridge City News. He has previously worked at City TV Calgary on the Breakfast Television morning show. He looks forward to connecting with this community, and reaching a new audience. Micah has a passion for interviewing and finding out why people think the way they do. You’ll often find him pursuing local feature stories and hard news. | <urn:uuid:8c3edcc3-3f3f-4332-8346-a924cb963be3> | CC-MAIN-2022-33 | https://bridgecitynews.ca/local-farmer-talks-agriculture-safety-week/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.966013 | 152 | 1.546875 | 2 |
Mikayla Viny, Ava Binder
The transgender community in Thailand varies greatly from that in the United States. In Thailand, they recognize a third gender, which is termed “Kathoey”. This term was originally used to describe gays or feminine males, but now it is widely used to specifically describe male-to-female (MTF) transgender people. Over the past decade, Kathoey has been recognized constitutionally in hopes that introducing an additional gender identity will help reduce discrimination throughout the country of Thailand. While there has been a raise in awareness about this topic, people in Thailand who identify as Kathoey still face many societal barriers that many transgender people in the United States also encounter on a normal basis.
In Thailand, there is an impression that the Kathoey are pretty well accepted. They are seen everywhere and seem to live just like anyone else in the society. Unlike the United States, there is not a lot of violence against the transgender community there. However, the Kathoey do have a difficult time when it comes to the professional workplace. “First of all in Thailand, we’re pretty well-accepted, we can walk in the street and we don’t have to fear that someone’s going to shoot you in the head. At the same time, the most difficult thing is at a professional level, that people don’t accept people like us,” said Jenisa Limpanilchart, a businessperson in Thailand, to CNN. No matter their educational level, background, or experience, many companies do not want to hire them and there is no legal procedure in place that deals with how to handle this type of discrimination. These type of issues also occur regularly in the US.
Since 2015, there has been a lot of discussion about the third gender in Thailand in relation to political and social issues. The biggest controversy with this is Thailand’s army draft. Every year, Thai men who are 21 years old must either volunteer themselves to serve in Thailand’s army for six months or take their chances in a lottery. This lottery is when a man either gets a black ticket which allows them to go home, and if they get a red ticket, it means that they must serve for at least two years. This draft is particularly troublesome for transgender people because some kathoey believe that since they were born male, is it their duty to be a Thai soldier. Furthermore, people who identify as kathoey are put at risk of stress and humiliation during the draft itself. It becomes an issue of human rights more than anything else. Many transgender women who are drafted fear that they will be undressed, stared at, and publicly embarrassed, making the whole process far more difficult. As for the army draft, exemptions can be made under certain circumstances. These include when someone is physically or mentally incapable of serving in the army, or for transgender women, if they can prove that they are not identifying as female to be exempt from serving in Thailand’s army. This further explains how even though kathoey in Thailand are widely acknowledged, they still face typical transphobia and discrimination on a regular basis.
While it does seem as if the Kathoey in Thailand are much more widely accepted than the transgender community in the United States, that is not always the case. While the Kathoey still live as normal members of the society and are tolerated, they face a fair amount of discrimination. It is difficult for them to get hired by companies, and even if they do get hired they still face many challenges in the workplace. On top of that, there are issues with the army draft system in Thailand. Some citizens believe that since the Kathoey were born male they should be forced to participate in the draft, but others believe that this causes too much humiliation and they should not be forced to potentially serve in the army. These are similar issues to the ones that the transgender community faces in the US. Certainly none of these issues of discrimination are going to be solved overnight, but steps are being taken to do so, such as the push to include a third gender in the Thailand constitution and government documents.
Lefevre, A. (2016). Thailand Makes HUGE Move For Its LGBT Community. Retrieved 2018, from https://www.huffingtonpost.com/2015/01/15/thailand-third-gender-_n_6476582.html
Park, M., & Dhitavat, K. (2015). Thailand’s new constitution may recognize third gender. Retrieved from https://www.cnn.com/2015/01/16/world/third-gender-thailand/index.html
Reuters. (2017). Nightmare looms for transgender women at Thailand’s army draft. Retrieved 2018, from https://www.nbcnews.com/feature/nbc-out/nightmare-looms-transgender-women-thailand-s-army-draft-n743921
Szreder, J. (2017). Ladyboys: The third gender in Thailand. Retrieved from https://www.theblondtravels.com/ladyboys-third-gender-thailand/
Winter, S. (2010). Why are there so many kathoey in Thailand? Retrieved 2018, from http://www.transgenderasia.org/paper_why_are_there_so_many_kathoey.htm | <urn:uuid:7020853d-8391-4275-be39-acda34dfd592> | CC-MAIN-2022-33 | https://maytermthailand.org/author/mikaylaviny/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573399.40/warc/CC-MAIN-20220818185216-20220818215216-00072.warc.gz | en | 0.960998 | 1,133 | 2.3125 | 2 |
I have two questions for you: Are you a self-learner? Then how do you stay up to date? What should you focus on if you’re a beginner, or if you’re more advanced?
And here is my second question: Are you working in biomedicine? And if you do, are you using Bayesian tools? Then how do you get your co-workers more used to posterior distributions than p-values? In other words, how do you change behaviors in a large organization?
In this episode, Eric Ma will answer all these questions and even tell us his favorite modeling techniques, which problems he encountered with these models, and how he solved them. He’ll also share with us the software-engineering workflow he uses at Novartis to share his work with colleagues.
Eric is a data scientist at the Novartis Institutes for Biomedical Research, where he focuses on Bayesian statistical methods to make medicines for patients. Eric is also a prolific open source developer: he led the development of pyjanitor, an API for cleaning data in Python, and nxviz, a visualization package for NetworkX. He also contributes to PyMC3, matplotlib and bokeh.
This is « Learning Bayesian Statistics », episode 5, recorded October 21, 2019.
Our theme music is « Good Bayesian », by Baba Brinkman (feat MC Lars and Mega Ran). Check out his awesome work at https://bababrinkman.com/ !
Links from the show:
- Eric’s website: https://ericmjl.github.io/
- Eric on Twitter: https://twitter.com/ericmjl
- Bayesian analysis recipes: https://github.com/ericmjl/bayesian-analysis-recipes
- Bayesian deep learning demystified: https://github.com/ericmjl/bayesian-deep-learning-demystified
- Causality repo: https://github.com/ericmjl/causality
- Pyjanitor – Convenient data cleaning routines for repetitive tasks: https://pyjanitor.readthedocs.io/
- PyMC3 – Probabilistic Programming in Python: https://docs.pymc.io/
- Panel – A high-level app and dashboarding solution for Python: https://panel.pyviz.org/
- Nxviz – Visualization Package for NetworkX: https://nxviz.readthedocs.io/en/latest/ | <urn:uuid:cb66bab9-bd26-476b-bde3-8263707c210b> | CC-MAIN-2022-33 | https://learnbayesstats.com/episode/5-how-to-use-bayes-in-the-biomedical-industry-with-eric-ma/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.878243 | 543 | 1.726563 | 2 |
Two components make up the ODU signature: the word mark and the logo. The word mark is rendered in the Beaufort Bold font (caps and small caps). The crown is a fresh expression of the qualities of prestige and leadership.
When presented in full color, the signature employs the school colors PMS 540 (blue) and PMS 430 (gray). When presented in a single color, 100% black or 100% PMS 540 is used to maintain the dimension of the signature. When reversed, the background must be a dark value so that the signature is clearly read - 100% black or PMS 540 is preferred.
ODU Full-Color Signature
ODU One-Color Signature
ODU One-Color Reverse Signature
ODU Full-Color "ODU" Signature
Keep the ODU signatures clearly visible. It is important to maintain a sufficient amount of space around the signature to ensure that it is distinct and easily identifiable. As a general guideline, the space around the signature should be the same as the height of the logo and "OLD DOMINION", or in the case of the ODU signature-the height of the logo and "ODU". No graphics, type or illustrations should appear in this clear space.
To ensure that the signature is legible, it's width should be no smaller than 1.75" for the full signature and for the "ODU" signature, no smaller than ".625".
Acceptable Signature Backgrounds
Legibility is paramount in the usage of the ODU signature. Therefore it should always be clearly visible against a background. All versions of the signature must appear on a white or very light (a color no darker than the look of a 10% screen of black) colored background. The reversed signature should be used on black, PMS 540 or suitable dark backgrounds. When placed on a photographic background, the area of the photograph where the signature is placed must be light or dark, not overly textured, or complex.
Incorrect Usage of Signature
To maintain the integrity of the ODU signatures they must be used within the guidelines outlined in this manual. Below are several examples of incorrect usage.
When resizing the signature, do not distort it. In Word and PowerPoint particularly, only drag on the corners of the logo to resize correctly.
Using logo mark or word mark only
Do not separate the word mark from the full logo.
Altering the opacity
The ODU signature should be used at 100% opacity.
Altering the color
Use only the approved options for the ODU signature. | <urn:uuid:3f1add67-2fd1-49f1-b092-afb40ff4f99e> | CC-MAIN-2022-33 | https://www.odu.edu/facultystaff/communication/toolkit/identity-standards/logo.html/facultystaff/communication/toolkit/identity-standards/logo | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.849331 | 538 | 1.78125 | 2 |
FROM THEN... TO NOW.
Elizabeth Farms began as The Elizabeth Furnace Plantation in the 18th century. Furnace founder and original owner of the property John Jacob Huber transformed the property to accommodate the furnace and ironwork industry during the colonial-era. In 1752 Hubers daughter, Elizabeth, married a German employee of her father, Heinrich Wilhelm Stiegel. By 1757 Stiegel had bought the Elizabeth plantation and renamed it the Elizabeth Furnace after his wife, and the daughter of its founder. With financial backing of Philadelphia investors, Stiegel constructed many of the historic buildings the plantation held.
Elizabeth Furnace was later acquired by the Coleman family when Stiegel and his extravagant taste landed him in debtors prison in Philadelphia by the early 1770’s. Creditors eventually leased the furnace to a young iron master name Robert Coleman. Coleman managed the furnace with enough skill he was able to eventually earn enough to purchase the property before his 7 year lease expired. The mansion Coleman built in 1788 remains standing today on the property off of Rt 501.
Since the recent sale of the property in October 2021 this historic farm which has been functioning as a successful Christmas tree farm for the past 30 years will continue on its path to expand to weddings, corporate events, agritourism & many other family friendly seasonal activities!
We are proud to announce a new adventure at The Barns at Elizabeth Farms as the brand new owners showcase their passion for creating a wholesome family friendly environment while sharing this beautiful historic property with you throughout the entire year! | <urn:uuid:4691d37c-e15b-4877-9e3c-6b156fe20892> | CC-MAIN-2022-33 | https://www.thebarnsatelizabethfarms.com/the-farm | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.967576 | 325 | 1.84375 | 2 |
Pulsed Light Treatment of Vascular Lesions
The human body is rife with many types of skin irregularities, some of which are mild and inconspicuous, while others are more complex and severe. Birthmarks, also known as vascular lesions in medical terms, are a typical anomaly that people encounter. The condition is caused by a skin or tissue anomaly that, in most cases, has no medical consequences.
Vascular lesions, such as Haemangiomas, pose no health risk. At most, people with this anomaly may just require cosmetic therapy. Otherwise, there is no need for medical treatment. However, the need for treatment becomes critical when severe lesion conditions, like venous and vascular malformations, develop in the body.
Types of Vascular Lesions
Three major types of vascular lesions exist — vascular malformations, Haemangiomas, and Pyogenic Granulomas. On the surface, these anomalies look alike. Yet, their causative factors and medical treatment processes differ.
Most pieces of medical evidence point to the notion that vascular malformations are largely the result of genetics, while the other two are thought to be caused by toxic exposures.
As the name implies, vascular malformations centre on anomalies in the blood vessel formations. The affected vessels affect blood flow due to the presence of lesions. As a result, there is discolouration of skin tissues in such regions. Vascular malformations are grouped into the following:
- Lymphatic malformations
- Venous malformations
- Arteriovenous malformations
- Capillary malformations
These abnormalities have exclusive attributes and diagnoses, making each treatment strategy unique.
This is a frequent kind of lesion in children. They emerge pinkish-red (bright red for superficial haemangiomas) on the skin surface in the early stages following birth, before darkening with time. Haemangiomas vary in size and thickness depending on the severity of the lesion. It is, nevertheless, noncancerous.
Even then, if left untreated, the afflicted region may develop complications such as infection, bleeding, and ulceration (a malady that results in permanent scarring). Haemangiomas might take anywhere from 6 to 12 months to grow, and then stabilize. It diminishes and disappears after that, typically leaving behind fatty tissue or skin.
Depending on the afflicted area, severe instances of this condition might be catastrophic. For example, if it forms around the eyelid or the ear canals, affected children may experience permanent vision loss or hearing loss. To avoid such serious side effects, this abnormality would necessitate proactive medical treatment.
Like haemangiomas, pyogenic granulomas are noncancerous and appear as red polyp like or ulcerating lumps. They appear as a result of tissue injury and grow quickly, particularly in places like the fingers and lips. When agitated, pyogenic granulomas can cause bleeding. Pregnant women and children are the people who are most impacted by this condition.
Treating Vascular with Pulsed Light
Intensive pulsed light (IPL) is effective in treating the three types of vascular lesions discussed in this guide, and even more. How does the IPL device or system work? It produces a specific amount of light energy (IPL beam) that affects the targeted capillaries or blood vessels directly without damaging the surrounding skin.
The heat energy generated by the IPL device is absorbed by these blood vessels, spanning a predetermined target range, generally 1 - 3 cm of the skin. During the procedure, their walls become irreversibly fused, removing the lesion permanently. The doctor can modify the IPL system to reach specific depths depending on the severity of the condition.
As a result, the technique can address areas that would otherwise be inaccessible to treatment. A typical IPL treatment takes anywhere between 15 - 30 minutes. Each treatment is unique based on:
- The characteristics of vascular lesion
- Its localization, and then
- Its spread
Since this treatment is non-invasive, patients do not require general or local anaesthetics. They'll simply feel a mild tingling or warmth in the treatment area.
Identifying Ideal Candidates for Treatment
The doctor will conduct a prognosis to establish the type of lesion present before beginning intense pulsed light treatment. A review of the patient’s medical history will be required as part of the prognosis to determine the duration of the lesion development, skin type, previous skin treatments, and any other skin conditions present. After reviewing the patient’s overall medical condition, the doctor can devise an optimal skin treatment technique for vascular lesions.
Ideal Number of IPL Procedures Required
For mild benign lesions, patients only need one treatment session to get the desired result. However, if the condition severe that it affects specific areas in the body, then there would be a need for multiple sessions.
Once treated, the treatment area usually doesn’t experience vascular lesions, especially if the patient adheres to post-treatment instructions.
Pre-and Post-IPL Treatment Care for Vascular Lesions
Before undergoing IPL treatment for vascular lesions, a patient must take note of the following skin care guidelines:
- Apply numbing cream within 30 - 90 minutes before treatment
- Avoid suntanning
- Avoid medications that may trigger haemorrhage, including blood thinners (heparin and warfarin), vitamin E, ibuprofen, aspirin, fish oil supplements, ginkgo and ginseng
The patient will experience little to no discomfort following therapy. However, minor side effects such as flushing or inflammation may occur, which disappears within a day. The full effects of this IPL technique might be seen right away or during the next two weeks.
Applying a prescribed ointment to the treatment area would be required for post-treatment care. What's more? Within a couple of weeks, the patient should avoid direct sunlight and any other conditions that might trigger blood vessel dilation. These would include:
- Strenuous activities, including exercises
- Solarium, and
Additionally, the patient needs to apply sunscreen to the skin as a form of protection against direct sunlight. Such products should ideally have an SPF of 30 or higher; this is because the skin is oversensitive at this point and the blood vessels may most likely dilate.
Vascular lesions are frequent skin abnormalities that affect millions of individuals across the world. Most of these people had desired to get rid of them for a long time but had no access to the appropriate skin treatment technologies to do so with minimal or no adverse effects.
However, technological advancements in the medical field have remedied this problem, since techniques such as intense pulsed light (IPL) skincare system enables quick and effective treatments. Anyone with any sort of vascular lesion can have it removed immediately, without any downtime. | <urn:uuid:c2f11b1d-d4a0-4d24-be03-f709366609a4> | CC-MAIN-2022-33 | https://www.stephilareine.com/2021/07/pulsed-light-treatment-of-vascular-lesions.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571692.3/warc/CC-MAIN-20220812105810-20220812135810-00072.warc.gz | en | 0.918385 | 1,470 | 3.15625 | 3 |
Tapped-out pipelines cause gas shortage in Mexico
MEXICO CITY (AP) — Motorists lined up for a fourth straight day at gas stations in western Mexico Tuesday as the government continued to restrict pipeline deliveries to combat illegal fuel taps.
With pipelines riddled with illegal taps drilled by fuel thieves, the administration of President Andres Manuel Lopez Obrador has switched to shipping fuel by tanker truck in a few western and central states. But there aren’t enough trucks for the task.
Lopez Obrador said fuel theft gangs have grown so bold — and have so many connections inside refineries — that they’ve been stealing gasoline and diesel directly from plants.
Lopez Obrador said soldiers dispatched to guard depots and refineries found a 2-mile (3 kilometer) long hose leading from one refinery to a tank outside.
Authorities said Monday that attempts to re-open a key pipeline were abandoned after the duct was found to be leaking fuel at numerous points.
Gov. Enrique Alfaro of the western state of Jalisco said officials of the government-owned oil company, Petroleos Mexicanos, or Pemex, had briefly tried to resume shipments through a pipeline to a refinery in the neighboring state of Guanajuato, “but the pipeline was so damaged that re-opening it was impossible.”
Pemex released a statement later Tuesday urging patience from Mexicans and calling on them to avoid “panic purchases” because there is enough fuel to meet demand across the country.
It said the shortages are being caused by “a logistical adjustment” as measures are taken to prevent fuel theft. The statement said that supply would be restored “in the short term” but did not give an exact time.
Patience was running thin in some cities where insufficient amounts of gasoline arrived by tanker truck and many stations have closed.
People lined up with jugs in hand to buy small amounts of gasoline and some stations limited purchases to 2.5 to 5 gallons (10 to 20 liters) or less.
The long lines have reportedly begun to encourage small-scale reselling of gasoline by private individuals, something that could foment exactly the kind of fuel-theft rings Lopez Obrador is trying to combat.
The head of the Mexican Employers’ Federation told the newspaper La Jornada that the fuel shortages “could foment illegal activities” because people may be willing to pay resellers more.
The opposition National Action Party said 84 percent of gas stations were closed in Guanajuato, a state it governs, and claimed the figure reached 90 percent in the state of Michoacan.
“To fight fuel theft, they had the bright idea of shutting down pipelines,” the party said in a statement. “By that logic, to combat thefts from ATM machines, you should close all the automatic tellers. It is absurd.”
Lopez Obrador said fuel theft costs the government $3 billion per year and the gangs are so sophisticated that they have established an alternative, clandestine and illegal distribution network with their own depots.
Lopez Obrador said some gangs had actually built warehouses over pipeline rights of way to drill illegal taps into the ducts. At big construction projects, the gangs would set up sales points to supply stolen diesel to heavy equipment operators.
Lopez Obrador said the during his strategy of deploying military personnel to guard distribution depots and refineries and to shut down tapped pipelines has already led to a decline in thefts during his first month in office. | <urn:uuid:33f3ae8e-b109-4ef6-8ab8-db3899bfcb68> | CC-MAIN-2022-33 | https://apnews.com/f9dd9df53ec74def94d33d09a4a57570 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.968919 | 739 | 1.992188 | 2 |
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Read the material about Primitivism in traditional Western Art and consider questions of “The Other” Who do you consider “we” and who do you refer to as “they?” Do the “We’s” and the “They’s” ever change? Does the artworld reinforce a separation or does it currently bring blur boundaries and differences?
Can the body be used as an art form without “othering” the model? Is the connection of the nude female with the wild and primitive something that still occurs in popular imagery.
If you have not heard it, listen to Chimamanda Adiche “Danger of a Single Story” on Ted Talks. What are the single stories in Art History? Are there examples of how art can show multiple viewpoints?
Research Mona Hatoum,Halim Al Karim Shirin Neshat, or Sanja Ivekovic with material found under ARTISTS or from your own searches and observe your own reactions.
Do concepts of “the Other” influence the way you view art or does art change your ideas about “the other?” | <urn:uuid:677bfbc4-4146-49fd-a162-72a098baf3aa> | CC-MAIN-2022-33 | https://firstgrader.net/buy-essay-online-4038/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.930612 | 313 | 3.28125 | 3 |
“Easter” Activity Sheet for your word work center. Great Literacy Center or sponge activity! Also, makes a great addition to your substitute file!
Three different activity sheets – pick the version you want your students to use!
In this Spy-A-Word activity, students make words out of the letters in “Easter”. They cut out the letters to form words. Then, they write the words in the blanks and color the page.
1. 3 Different Activity Sheets to choose from
2. “I Can” Sign for Center
3. Cut out letters in upper and lowercase
4. Answer Key showing possible words that can be made with these letters.
Making their own words is a great center activity! | <urn:uuid:25811976-8beb-4675-aecb-f4a3004df11c> | CC-MAIN-2022-33 | https://www.madebyteachers.com/products/easter-bunny-word-activity-word-work-center/?add-to-cart=122109 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.870655 | 165 | 3.40625 | 3 |
It’s the most wonderful time of the year! Christmas trees, wreaths, candles, strings of lights, stockings, and presents litter your home. During such a joyous season you should be celebrating with loved ones. Unfortunately it’s also the time of year when fire-related injuries and deaths soar. According to the National Fire Protection Association, 30% of home fires and 38% of home fire deaths occur in December, January, and February. From 2004-2008 an average of 260 home fires each year started with Christmas trees and an average of 150 home fires per year were caused by holiday decorations. There’s also an increase in injuries caused by falling off ladders while decorating and tripping over extension cords. Follow these safety guidelines and celebrate a stress-free holiday.
♦ First, test all smoke alarms. They can save your life if anything goes wrong.
♦ To avoid open flame hazards, try using battery-powered candles. If you choose traditional candles, make sure they’re never left unattended or placed in an area where they may be knocked over.
♦ Live trees embody the spirit of Christmas, but they can pose fire hazards. Make sure you purchase a fresh one and keep the stand filled with water to prevent it from drying out. And find a place to recycle your tree right after the holidays as it will dry out more and more the longer it’s up.
♦ If you decide to buy an artificial tree, make sure it’s labeled “fire-resistant.”
♦ Keep all decorations, especially trees, at least three feet away from heat sources.
♦ Not only are LED lights energy-efficient, but they’re also cool to the touch, unlike incandescent bulbs. They’re also more durable, making them much safer to use for decoration.
♦ When decorating the outside of your home, make sure all decorations and extension cords are marked for outdoor use.
♦ Before and after hanging lights, make sure none have been damaged either in storage or while they were out. If so, toss them so you don’t accidentally use them next year.
♦ Turn off all lights when leaving the house or going to sleep. This will prevent overheating.
♦ Overheating can also occur if you overload an electrical outlet, so keep in mind how much you’ll be plugging in and be sure to purchase a surge protector.
♦ We all love the holiday season, but try not to keep your decorations up for too long. They’re typically meant for temporary use and aren’t made to withstand extended periods of time exposed to weather and other damaging elements.
♦ All light strings and extension cords should be kept dry, both while they’re out and in storage.
♦ If you need to use a ladder, make sure it’s wooden or fiberglass as metal ones conduct electricity.
♦ No wires or cords should be pinched in doors or windows or run under heavy furniture and rugs.
♦And many decorations can be harmful to young children:
◊ Light strings and garland are strangulation hazards
◊ Avoid using sharp or breakable decorations and ornaments in case a child gets hold of one
◊ Make sure any small (“mouth-sized”) decorations are kept out of reach | <urn:uuid:1f34b27e-3c50-4997-9364-99355b1db10d> | CC-MAIN-2022-33 | https://www.nickleelectrical.com/18-holiday-decorating-tips-to-keep-safe/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.937334 | 695 | 2.984375 | 3 |
A new article out of Ning Yan’s lab has been published in the International Journal of Biological Macromolecules about functionalized lignin nanoparticles written by Hetian, Fangeng Chen, Wenxiang Zhu and Ning Yan.
Click here to view the full article for free until June 16, 2022.
There is a strong interest in developing environmentally friendly synthesis approaches for making polyurethane elastomers (PUE) with desirable mechanical performance and flame retardancy suitable for a variety of applications. Hence, in this study, a novel nano functionalized lignin nanoparticle (Nano-FL) containing nitrogen (N) and phosphorus (P) moieties was developed via mild grafting reactions combined with the ultrasound method. The Nano-FL incorporated in the PUE acted as both crosslinking agents and flame retardants. The novel Nano-FL showed good compatibility and dispersibility in the PUE matrix, thereby overcoming the weakening effect of adding traditional lignin flame retardants on the mechanical properties of the PUE materials. PUE/Nano-FL exhibited strong tensile properties. Compared with control neat PUE, with 10 wt% of Nano-FL addition, the PUE attained a limiting oxygen index as high as 29.8% and it also passed the UL-94 V-0 rating. Furthermore, Cone Calorimetry Test (CCT) showed that the addition of Nano-FL not only reduced the heat release rate and the total heat release but also decreased the total smoke production rate during combustion. The char residues of PUEs with Nano-FL showed a high oxidation resistance with dense and continuous structural morphologies. The combined barrier and quenching effects of the char layer provided excellent flame retardancy performance. The novel Nano-FL developed in this study showed excellent promises as green functional additives for enhancing mechanical, thermal and flame retardancy performance of a wide range of polymers. | <urn:uuid:63bf19fc-d5d9-4d09-97ec-cca589a8ade8> | CC-MAIN-2022-33 | https://ningyanlab.com/2022/04/28/new-article-functionalized-lignin-nanoparticles-for-producing-mechanically-strong-and-tough-flame-retardant-polyurethane-elastomers/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.916357 | 397 | 1.835938 | 2 |
I am very proud as the Headteacher of St Michael’s Catholic Primary to introduce you to our wonderful school. The opportunity to educate children is a privilege and one we take very seriously.
St Michael’s School offers a curriculum for all children which engages and helps children to know more and remember more.
Children, staff, Governors and parents work extremely hard to ensure St Michael’s is a happy, safe and supportive environment.
To learn more about our curriculum please look at our curriculum page. Our curriculum develops well rounded citizens with a clear understanding of values such as love, responsibility and friendship.
‘St Michael’s is a warm and welcoming school where everyone shares the headteacher’s clear vision. The mission statement, ‘Finding Christ in each other radiates throughout the whole school community’ – Diocesan Inspector
‘We have noticed a real positive change in our children’s development since joining St Michael’s’ – Parent
‘St Michael’s has brought out the best in my child and its wonderful to see them so happy’ – Parent
The views of our children are listened to through the many pupil voice groups we have in school.
‘Pupils make an outstanding contribution to the life of the school from their time in reception, as part of a ‘family group’, through to year six. They appreciate the outstanding personal support and care shown by the staff.’ – Diocesan Inspector
Our staff dedicate their time to provide the children in their care with the best possible academic education. However, we work equally hard to bring out all those hidden God-given gifts and talents in each and every child, to teach them good values by which to live by, to prepare them for the fast changing world in which they live. We consider our children as individuals. who are facing future challenges and ultimately leave us secondary school ready having enjoyed and embraced their learning experiences along the way.
If you are looking for a school for your child and are considering St Michael’s please give us a call and we can organise a visit to our lovely school. There is a dedicated page on our website that will give you information about starting school here at St Michael’s, please take a look. If you have any questions, please feel free to give us a ring.
Mrs J Bruton
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The European Parliament is challenging the national power monopolies
Members of the European Parliament have gained great influence in trade policy, thereby challenging the national monopolies of power. Often, they are perceived as a disturbing element in international negotiations.
The United States and the EU have been negotiating the Free Trade agreement TTIP since 2013, but have faced loud opposition from "disturbing elements" in the European Parliament. Here illustrated with the two Italian MEPs Marco Affronte and Laura Agea from the euroskeptical party group EFDD. Photo: European Union, 2015
- Guri Rosén is an expert on the European Parliament, EU external trade policy, and EU foreign and security policy.
- Rosén currently conducts research on the use of secrecy in EU trade policy and EU foreign policy.
Traditionally only technocrats and members of governments have played a role in international negotiations, explains Guri Rosén, post doctor at ARENA Centre for European Studies at the University of Oslo. Elected Members of the European Parliament (MEPs) were essentially excluded from trade policy and foreign policy. But since the Treaty of Lisbon came into force in 2009, the power of the European Parliament has significantly increased, partly because the MEPs participated in the formulation of the EU Constitution.
In her research, Rosén analyzes what kind of influence MEPs have got and how they are handling their new and extended role.
– The move towards involving the European Parliament more directly in policy making, had to do with ideas of democratization, rights and legitimacy. In the years after the Treaty of Lisbon, the European Parliament has become a much clearer voice of the citizens of the EU, says Rosén.
According to Rosén, the Treaty of Lisbon represented a small revolution in trade policy: It gave the European Parliament veto power over international trade deals, and decision making authority over trade legislation in general. It also put an obligation upon the technocrats in the European Commission to report regularly about the progress in international trade negotiations to the European Parliament.
The TTIP controversy
As a consequence of the greater involvement of the European Parliament in trade negotiations, other interests and values were emphasized, also those not directly related to the trade itself, such as sustainable development, human rights and digital security.
– How do the technocrats react to this?
– In order to interact with the MEPs, the technocrats have seen the need to use a somewhat different language. While the MEPs want to discuss politics, sustainable development and human rights; the technocrats focus on technical details, such as the effects of licensing processes and increased tariffs.
The greater involvement and visibility of the MEPs is clearly demonstrated in the negotiations on Transatlantic Trade and Investment Partnership (TTIP), according to Rosén. Especially in Germany, the TTIP was high on the agenda: There were a lot of protests, organized by NGOs and civil society organizations, which undoubtedly affected some MEPs and led them to oppose parts of the agreement, especially the controversial dispute settlement mechanism.
Lack of support from voters
Through her research, Rosén has found that the MEPs are increasingly challenging the power of national governments.
– MEPs claim their right to exert influence over trade deals, which is something qualitatively new, at least in a European context. How many times have Members of Stortinget, the Parliament in Norway, been involved in trade deals? she asks rhetorically.
– The EU is regularly criticized for its democratic deficit. Is the increasing influence of the MEPs part of a move towards greater democratization?
– Potentially yes. The Parliament is the only popularly elected body in the EU, and its role is to make sure that questions important to “regular people” are taken into account in trade deals. Because they are in regular contact with the EU Commission and have access to information, they are also able to follow trade policies more closely than before. Nevertheless, the European Parliament still faces a lot of democratic problems. While its power increases, support from voters decreases. A lack of public awareness around their efforts and achievements, undermines the contact with citizens.
The European Parliament as a disturbance
Reaching a trade agreement often takes several years. Most of them are already settled when presented to the Parliament, also in Norway, and there is always a risk that the national MPs may reject a trade deal which may have taken years to reach.
As such, Parliament Members are often seen as a kind of disturbing element in the finalization of a negotiation processes that were more than complicated enough already. Because of the risk of a veto, the MEPs are often included much earlier in the negotiations, such as in the TTIP negotiations, which may explain why the veto right is very rarely used. It is also in the interest of the European Parliament to avoid tensions around EU’s trade policy.
– Many MEPs would like the EU to involve in more trade deals. And this is a matter of trust and how responsible the EU wants to be seen as a trading partner, Rosén explains.
As such, MEPs are torn between the idea of promoting, not derailing, international negotiations, and still responding to the criticisms from civil society against trade deals.
– Talking at cross purposes
In the last few years, several extensive trade deals have come about, such as CETA (EU and Canada), TISA (EU, Norway and 21 other countries) and TTIP (EU and the US). These deals are challenging national sovereignty in a whole new way.
– Considering how much is at stake with these trade deals, shouldn’t one expect more political struggles on an earlier stage?
– Yes! These are enormous and decisive trade deals. Their size and complexity is something totally new, both when it comes to regulations – the so-called non-tariff barriers to trade – and the development of rules. The investor-state dispute settlement sparked enormous outrage and really put TTIP and trade politics on the agenda. Part of it has to do with the idea of dealing with American companies. Seeing how big and powerful they are, a lot of people fear that they may completely run over national governments.
The European Parliament is put under a lot of pressure from both the civil society and the business sector. While the opponents of the trade deals are emphasizing the principles, how the deals give preference to big business at the cost of national freedom; the supporters, on the other hand, use practical arguments, how the deals will be profitable and economically sound.
– The different actors keep talking at cross purposes, which precludes a real public debate, says Rosén.
A culture of secrecy?
In the beginning of the TTIP negotiations, it was mainly the interests of national and multinational companies that were taken into account, while civil society organizations were excluded.
Representatives from civil society were later included in the process, serving as an advisory panel to the commission after every round of negotiations. This panel is now a formal expert group.
– There is a danger that the Commission uses this expert group merely as a tactic, in order to silence various interests groups and avoid claims that the processes are excluding and undemocratic.
While greater transparency around trade negotiations is highly welcomed, it may also reveal the interests of the EU and thereby affect the negotiations, says Rosén. She also points out that many MEPs are shaped by the culture of secrecy, in which they have privileged access to information.
– MEPs have several times argued that secrecy is necessary to protect the interests and the security of the EU. Although this may be right, a lack of transparency always has to be thoroughly grounded and reflected upon. The people deserve to know why trade negotiations are given priority over democratic values. The NGOs and the civil society have to keep up the pressure to make sure the doors remain open, Rosén says. | <urn:uuid:156a84d1-568c-4ccb-b09f-3a69a45849be> | CC-MAIN-2022-33 | https://www.sv.uio.no/arena/english/research/news-and-events/news/2010-2020/2019/rosen-guri-ep-trade-policy.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.966251 | 1,599 | 2.203125 | 2 |
Smith, KJ and Blizzard, L and McNaughton, SA and Gall, SL and Dwyer, T and Venn, AJ, Takeaway food consumption and cardio-metabolic risk factors in young adults, European Journal of Clinical Nutrition, 66 pp. 577-584. ISSN 1476-5640 (2012) [Refereed Article]
© 2011 Nature Publishing Group
Background/objectives: Takeaway food consumption is positively associated with adiposity. Little is known about the associations with other cardio-metabolic risk factors. This study aimed to determine whether takeaway food consumption is associated with fasting glucose, insulin, lipids, homeostasis model assessment (HOMA) and blood pressure.
Subjects/methods: A national sample of 1896, 2636 year olds completed a questionnaire on socio-demographics, takeaway food consumption, physical activity and sedentary behaviour. Waist circumference and blood pressure were measured, and a fasting blood sample was taken. For this analysis, takeaway food consumption was dichotomised to once a week or less and twice a week or more. Linear regression was used to calculate differences in the adjusted mean values for fasting lipids, glucose, insulin, HOMA and blood pressure. Models were adjusted for age, employment status, leisure time physical activity and TV viewing.
Results: Compared with women who ate takeaway once a week or less, women who ate takeaway twice a week or more had significantly higher adjusted mean fasting glucose (4.82 vs 4.88 mmol/l, respectively; P = 0.045), higher HOMA scores (1.27 vs 1.40, respectively, P = 0.034) and tended to have a higher mean fasting insulin (5.95 vs 6.45 mU/l, respectively, P = 0.054). Similar associations were observed for men for fasting insulin and HOMA score, but the differences were not statistically significant. For both women and men adjustment for waist circumference attenuated the associations.
Conclusion: Consuming takeaway food at least twice a week was associated with cardio-metabolic risk factors in women but less so in men. The effect of takeaway food consumption was attenuated when adjusted for obesity.
|Item Type:||Refereed Article|
|Keywords:||takeaway food, cardio-metabolic risk, abdominal obesity, insulin, lipids|
|Research Division:||Health Sciences|
|Research Field:||Epidemiology not elsewhere classified|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Smith, KJ (Dr Kylie Smith)|
|UTAS Author:||Blizzard, L (Professor Leigh Blizzard)|
|UTAS Author:||Gall, SL (Associate Professor Seana Gall)|
|UTAS Author:||Venn, AJ (Professor Alison Venn)|
|Year Published:||2012 (online first 2011)|
|Web of Science® Times Cited:||37|
|Deposited By:||Menzies Institute for Medical Research|
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Montenegro is a regular European country. Tourism is a major source of income. For this reason Montenegro continues in its effort to simplify entry for foreigners year on year. Most visitors can spend a limited time here without a visa. For example, Russian citizens can continue their stay in Montenegro without a visa for 30 days. When the time limit is about to expire, it is simply a matter of exiting Montenegro to neighboring Bosnia and Herzegovina or Albania with subsequent re entry on the same day, the 30-day term then starts anew. Therefore leaving for just a few hours effectively allows you to stay in Montenegro for an unlimited time.
You can only exceed this 30-day grace period without leaving Montenegro if you have a tourist visa or a work permit (‘boravok’) in advance.
Neighboring countries vary in their entrance policies for Montenegro yearly. The current situation largely depends on the Balkan countries’ ongoing initiatives to affiliate with or join various international organisations and alliances.
Croatia -Montenegro border
Croatia officially entered the EU as a full-fledged member in 2012. You can now only enter Croatia with a Croatian visa or an open Schengen multiple entry visa. Croatia has not entered the Schengen Agreement yet, but it already recognises Schengen visas.
You can apply for a Croatian visa at any Croatian embassy. The documents required are almost identical to a Schengen visa application.
Foreign citizens staying in Montenegro on a long-term tourist visa or a work permit (‘boravak’) can apply for a Croatian visa in Montenegro via one of the Croatian consulates.
Croatian consulate in Kotor:
Stari Grad, Trg od oruzja bb, the building near the main gates.
Consul general – Božo Vodopija
Croatian consulate in Podgorica:
Ul. Vlada Četkoviča, 2
Consul – Petar Turčinovič
Be careful visiting Croatia in a car with Montenegrin registration plates. Remember, that only recently, during the 1990’s, Croatia had been in a bitter armed conflict against Serbia and Montenegro. Croatians who live in border regions up to Dubrovnik and Makarska can be hostile. Their displeasure usually manifests in unfriendly looks, but sometimes tires are slashed and windscreens shattered. However, Croatians are quite welcoming towards foreigners, including Russian language speakers. For your own safety and that of your car near Croatian border, displaying a note saying “RENT-A-CAR“. I am a tourist’ in large print under your front and rear windscreens. This simple measure has been tried and tested by local expats.
Bosnia and Herzegovina
From 2013 all Russian citizens need to enter Bosnia and Herzegovina is an international passport.
Before that a travellers also had to have a tourist visa, but this requirement has been lifted recently. Please note that visa-free period in Bosnia and Herzegovina is limited to 30 consecutive days.
Serbia -Montenegro border
One does not need any documents other than an international passport to enter Serbia. This applies all year round.
Russia actively disapproved of Kosovo’s separation from Serbia, so Serbia opened its borders on an ex parte basis as a gesture of gratitude and to ensure friendly relations.
Besides, the border between Serbia and Montenegro – friendliest Balkan countries – has simplified the procedures for crossing in both directions. It is easier to cross the Serbian-Montenegrin border than any of other Montenegrin borders.
Kosovo -Montenegro border
The country is relatively young and some of its institutions have still not reached maturity. Many state agencies are still developing and not fully established in their everyday activities. Legislative fundamentals are also being developed. The same applies to border crossing regulations. So far, there is no single uniform standard.
To enter Kosovo at the moment citizens of Russia, Belarus and the Ukraine need to obtain a visa in advance in their home countries. If you have a valid Schengen multi-entry visa, this is sufficient to cross the border with Kosovo.
Albania -Montenegro border
Entrance to Albania does not require a visa from June 10 to September 30. The exact timetable may vary yearly. You need only your passport to cross the border.
During the rest of the year (for Belarusian citizens all year round) one needs a visa to cross the Albanian border. The visa should be obtained in advance in the country of residence. In practice though, a valid Schengen visa will be enough. Albania is not on the list of the countries which signed Schengen agreement and its consulates cannot grant Schengen visas, but Albania wants to become a part of EU just like its neighbours, so exceptions are quite often made on the border.
A tourist who wants to go to Italy must have a valid Schengen visa obtained in advance in the country of residence. This is a core requirement. The only exception used to be a cruise tour “Bar-Bari-Bar” for citizens of Russia, Belarus and the Ukraine. This cruise stopped in 2013.
Montenegro has a sea border with Italy, but it is easy to get to Italy by car too. All year round a cruise ship goes from the Montenegrin city Bar to Italian city Bari. More details are available on the relevant page of our website.
It is impossible to come for a holiday in Montenegro and buy or obtain a Schengen visa in a more simplified way, despite rumours on the Internet. You can only apply for a Schengen visa in Montenegro if you live and work there with a tourist or business visa. In this case, the standard requirements for documents apply.
Italian embassy in Podgorica:
Ul. Džordža Vašingtona, 83
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A PET study of brain 5-HT 2 receptors and their correlation with platelet 5-HT 2 receptors in healthy humans
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RATIONALE: Platelets share many properties with brain serotonergic neurons such as active 5-hydroxytryptamine (5-HT) transport, 5-HT2 receptors, and mitochondrial monoamine oxidase. OBJECTIVES: We measured brain 5-HT2 receptors and platelet 5-HT2 receptors in healthy volunteers to determine if there was any correlation between the two measures. METHODS: Ten healthy volunteers with no lifetime history of psychiatric illness or family history in first-degree relatives were recruited. 5-HT2 receptor binding was determined for each subject with positron emission tomography and [18F]setoperone scan in the brain and with 3H-LSD binding in platelets. RESULTS: We found no significant correlation between 5-HT2 binding potential (BP) in platelets (Bmax/Kd) and a semiquantitative estimate of 5-HT2 BP in frontal, parietal, and temporal cortical regions. SPM voxel based analysis also showed no significant correlation between the 5-HT2 BP in platelets and in the brains of the study subjects. CONCLUSIONS: Brain 5-HT2 receptor binding was not significantly correlated to platelet 3H-LSD binding in healthy subjects. This raises questions about the validity of generalizing findings from platelet studies to 5-HT neurons in the brain.
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Maintaining family communications
Every year, thousands of children flee conflict and poverty in the Central American countries of Guatemala, El Salvador, and Honduras to seek safety and reunite with family in the United States.
The migration routes through Mexico often leave them vulnerable to violence and exploitation by gangs and traffickers.
Manuel was living with his mother in Honduras when he was threatened by a gang. He could either join or die. He left his hometown behind with just a backpack containing a few personal items, including contact information for his mother.
While traveling on La Bestia, a dangerous train often used by migrants to transit Mexico, he was robbed and lost all the information he had for maintaining communication with his family.
Upon arrival in the United States, he was detained at a shelter for unaccompanied children. While all the minors were given the opportunity to call home and let their loved ones know their whereabouts and wellbeing, Manuel was unable to do so, until the Red Cross stepped in.
Through the Restoring Family Links program, volunteers with the American Red Cross sat down with Manuel and gathered information about his mother. He drew a map identifying his home in relation to the local school and Red Cross. By using this map, the Honduran Red Cross was able to find his mother who provided her contact information as well as the information for Manuel’s aunt in the United States.
All migrants in the region face problems concerning safety and communication. The difficulties faced along migratory routes in tandem with the detention and deportation practices of nations in the region often put migrants’ lives in danger and limit the means by which they can communicate with family.
The Red Cross is dedicated to meeting the humanitarian needs of these individuals. Along the US-Mexico border, the Mexico Red Cross works to meet the basic medical needs of returned migrants, checking blood pressure and glucose levels, providing first aid, and treating dehydration. Throughout Mexico, the Red Cross uses mobile clinics to offer medical treatment and phone calls for those in transit.
Through partnerships with other humanitarian organizations aiding migrants, the American Red Cross is also at work along the US-Mexico border and along migratory routes in the US to help migrants maintain family communication and provide basic first aid.
Roberto benefited from this service after he was separated from the group he was traveling with. He wandered the desert for four days until he stumbled upon a camp where he could rest, receive basic medical treatment and contact his family.
His experience in the desert had such a terrifying effect that he was unsure of whether to continue his journey or to turn himself in and return to his family in Mexico. Through the phone service, he was able to call his family to ask their advice on the situation. Manuel expressed his gratitude for this service. “Being able to talk with my family made this difficult decision much easier. I feel comforted knowing the Red Cross can help me.” | <urn:uuid:a2093526-9b5d-4a84-b213-8956e111de8a> | CC-MAIN-2022-33 | https://ifrc-media.org/interactive/maintaining-family-communications/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.980045 | 586 | 3.1875 | 3 |
Blockchain technology, the infrastructure that supports the online crypto market still has a lot of potential to unpack.
2021 has kicked off to an action-packed start with cryptocurrency prices reaching record highs, sending digital markets into overdrive. According to crypto news, on Saturday 13th 2021, at 07:25 a.m. ET, the Bitcoin price reached a record high of $60, 415.34 according to San Francisco based digital currency exchange company Coinbase. Nothing seems to be stopping the digital currency which is up 963% over the last 12 months with a value surpassing $1 trillion for the second time this year.
Bitcoin and the many other digital currencies were developed using blockchain technology which uses distributed ledger technology that records information in a decentralized system. This technology facilitates a public ledger that cannot be manipulated and is accessible to all users. Blockchain ledgers provide a very secure mechanism for storing data as they cannot be modified retroactively and for privacy purposes, can be used anonymously.
One of the fundamental advantages of blockchain technology is the ability to cut out any intermediaries from the transaction. The fact that blockchain acts as a decentralized ledger for all transactions in a network means that individuals within these networks are responsible for confirming the transactions. This results in there being no need for a trusted third-party institution.
While blockchain has serious potential for high-powered applications in payment transactions, supply chain management and security, it is still a developing technology with a long journey ahead before it realizes such aspirations.
There are four main components on which blockchain is developed:
- Each participant in the network has concurrent access to view the data as it is stored within a distributed ledger.
- The integrity and security of the information is protected as a result of cryptographic safeguards.
- Adjustments can be confirmed directly between participants which replaces the need for an intermediary to authorize transactions.
- It incorporates smart contracts which allows automatic enforcement of the expected behavior of an asset or transaction embedded in the blockchain.
The above-mentioned conceptual designs create the opportunity to move away from traditional intermediaries. Additional benefits to blockchain technology includes increased security and transparency with a greater ability to track and manage transactions. The benefits will inevitably reduce costs and create additional security for companies that employ blockchain technology.
Blockchain and Real World Applications
The first to assume blockchain technology were of course organizations within the financial services industry with two specific areas of focus; the crypto market and infrastructure. The implementation of cryptocurrencies includes payment transactions, wallets and digital currency exchange.
Blockchain technology has the ability to provide solutions for infrastructure problems by replacing outdated systems and networks for trading and exchange transactions. This updated infrastructure could reduce costs, fraud and risk that is intrinsic to traditional transaction authentication and the management of ledgers and registries.
Blockchains can also remove repetition, source code management problems and communication delays which are all inherent in traditional banking systems as each transaction is only processed once in an individual shared electronic ledger.
Blockchain: Risks and Threats
While the future of blockchain technology looks bright, we must still remember that new technologies bring new risks and various complications that require working solutions. Blockchain is still a developing technology and therefore needs to be fully tested before it can be scaled for more extensive use in other industries.
Indeed, blockchain technology has its own, unique security measures. There are still however certain risk factors if the infrastructure, hardware and software systems around blockchain technology have significant weaknesses.
Substandard systems which have been improperly designed leave the blockchain exposed to cybercrimes and hacking. Privacy of information and risks associated with personal identity is still a notable concern. Users of public blockchains are generally identified with an alias and as transactions are encrypted, no private information is distributed. This anonymity has both positive and negative consequences; it protects users’ identities but also creates a safe haven for cybercrime and other criminal behavior to perpetuate.
Recovering Stolen Crypto
Cryptocurrency intelligence reporting has developed significantly over the last few years thanks to the rise in bitcoin scams and other cybercrimes. Several software programs and investigative techniques now have the ability to trace numerous types of cryptocurrency including Bitcoin, Ethereum, Ripple and Litecoin to name a few.
Victims of cyber fraud and crypto scams are typically unfamiliar with cryptosecurity and the prevalence of online crime and cybertheft. Blockchain analysis and digital currency investigation services provide victims with the information needed as a first step to recovering their funds.
Before recovery efforts begin, transaction IDs of transactions are required. These IDs allow investigators to track transactions and determine exactly where the digital coins are moving. Although it is possible to proceed with an investigation without these IDs, having a record will help advance the investigation and help minimize any possible complications.
With most blockchains, a transaction ID is the distinctive series of letters and numbers which represent a ledger of the movement of digital currencies from one address to the next. This is also commonly referred to as the transaction hash which specifies the date, time, sending and receiving addresses, transaction amounts and other critical information.
To provide further insight into the incident, supporting information and documentation will assist in the investigator’s understanding of the movements of the funds. Important information to include are all transaction IDs, where the crypto currency was sent from, where you believe cryptocurrencies were being sent and all available information on the scam and cybercriminals involved in the transaction.
The final step in your crypto recovery after dealing with a fake cryptocurrency exchange is to contact a well established and trusted investigation firm. MyChargeBack is an American fund recovery company which provides a number of services to assist individuals affected by cryptocurrency fraud. Recovery solutions include in depth investigation and analysis, assistance with providing evidence to law enforcement and filing a case and presenting evidence in court.
MyChargeBack provides free consultations. Chargeback and other fund recovery programs contracted thereafter are subject to retainers, fees and/or commissions depending on the individual case history and the type of service selected. MyChargeBack does not offer any financial investments or advice. | <urn:uuid:9d903b11-63d1-47c8-9f3a-51c642a79c1b> | CC-MAIN-2022-33 | https://www.fxstreet.com/education/crypto-markets-blockchain-trends-technologies-risks-and-recovery-options-in-2021-202103261018 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.940227 | 1,213 | 2.421875 | 2 |
Book Recommendations for 6th Grade by 6th Grade Boy
HI! My name is Josh and I’m 11 years young. I just happened to come across your website as I was searching for some books. I looked over a few of your lists and I found some very interesting books! I thought that I could send in some recommendations, but I found most of mine on one of your lists! I saw The Mysterious Benedict Society on a list which is my all-time favorite books! I’ve also read Savvy, which is my 3rd favorite book. So here are a few books that I just want to recommend.
The 1st book is The Candymakers by Wendy Mass. It’s about 4 kids that are competing in an annual competition to launch a candy out into stores across the world. The book is filled with mystery and suspense. I would definitely recommend this to any child from 5th to 8th grade. Another book that I’d recommend, is The Name of this Book is Secret by Pseudomys (can’t spell first name) Bosch/ Rafael (forget the last name. The thing I loved the most about that book was the narration. I also liked the books The Genius Files by Dan Gutman and The Westing Game by Ellen Raskin.
Thank you for letting me share! Please respond!
I would love to post on your list. Can you give me your 10 favorite books in the order of how much you like them? Ask your mom if I can post it. I would use your email as the intro about you and would not use your last name for internet safety reasons. I like your book choices by the way. The Candymakers is great!
Thank you! She said yes. Here they are in order:
1. The Mysterious Benedict Society by Trenton Lee Stewart*
2. The Candymakers by Wendy Mass*
3. Savvy by Ingrid Law*
4. The Name of This Book is Secret by Pseudonymous Bosch*
5. The Westing Game by Ellen Raskin
6. The Genius Files: Never Say Genius by Dan Gutman
7. The Girl Who Could Fly by Victoria Forester
8. The 39 Clues series by Rick Riordan
9. How to Survive Middle School by Donna Gephart (I think there might be a few books with that title)
10. Diary of a Wimpy Kid series by Jeff Kinney*
I wanted to suggest more chapter books for you to try. You gave me 10 so I want to return the favor.
There is a new Mysterious Benedict Society coming out! My 6th grade daughter and I are very excited about it!
The Extraordinary Education of Nicholas Benedict (The Mysterious Benedict Society) by Trenton Lee Stewart
I thought Cosmic by Frank Cottrell Boyce was a little like The Candymakers. You might really like it.
I’ve always loved Mudville by Kurtis Scaletta
The Case of the Deadly Desperados by Caroline Lawrence is also right up your alley. It’s a Western action-adventure set in 1862 but it has a comic book non-reality feel and the 12-year-old lead character, P.K. Pinkerton is very subtlely autistic.
Time Snatchers by Richard Unger. My 6th grade daughter likes most of the books on your list. She read this book that was meant for me first and gave it a thumbs-up as a thrilling action-adventure.
Dead End in Norvelt by Jack Gantos. The winner of the 2012 Newbery Award, it’s a small town quirky mystery novel. I think you might like it! I did!
Holes by Louis Sachar. I’m assuming you’ve read this but if not, my daughter recommends it for you. | <urn:uuid:2f7ee81b-c613-44d4-aee0-829db7d55798> | CC-MAIN-2022-33 | https://www.pragmaticmom.com/2012/04/6th-grade-boy-shares-10-favorite-books/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.967387 | 826 | 1.703125 | 2 |
Pie or Doughnuts?
Pie charts are one of the most common and easily understood graph types. They are used to plot relative percentages among categories of a given variable. The circular “pie” is the whole — the total value of all categories — and each category is a “slice” whose percentage of that whole is proportional to the length of its projected arc.
Doughnut charts (aka “Donut” charts) are an extension of pie charts. The doughnut chart allows the presenter to combine the information of multiple “pies” into a single graphic, thus producing gains in both economy of space and of ease with which the viewer can spot trends over time. On the other hand, multiple pie charts may be preferable when the presenter needs to draw attention to relative proportions, as the ring structure of the doughnut chart emphasizes the outer plots and de-emphasizes the inner plots.
Fresh Doughnuts, Refreshed Pie
Doughnut charts are one of several new plot types added for Origin 2020. Considerable effort went into making Origin’s doughnut chart highly customizable. In the process, Origin’s familiar pie charts got an overhaul and gained a whole slew of customizable new properties. In this blog post, we’ll showcase a handful of the new pie and doughnut charts and highlight some key customization options.
Previously, Origin shipped with two built-in pie chart templates — the 2D Black & White Pie Chart and the 3D Color Pie Chart. The two were cousins: You could create a 2D B&W Pie Chart from a 3D Color Pie Chart or vice versa, using the controls in Plot Details . I mention this because the old 2D B&W Pie Chart is out for Origin 2020 and is replaced by a 2D Color Pie Chart. If you liked the old 2D B&W chart with hatch patterns, you can easily recreate that template by customizing the new 2D Color Pie and saving it to your User Files Folder with a new name (e.g. “2DBWPie.otpu”).
As mentioned, there are many new properties and several new pie chart templates for Origin 2020. You’ll find them in the menu under Plot: 2D Basic, alongside the new doughnut charts. Here are some examples that you can find in the Learning Center (press F11):
Pie of Pie, Bar of Pie, and Doughnut of Pie
- Combine Wedges by Percentage, by Value or Custom (you pick manually).
- Show Combined as Pie, as Column or as Doughnut.
Pie with Different Radius
- Increment Radius using data values in a worksheet column of your choice.
Doughnut with Total
- Set Wedges Total by Percent or Value and specify the quantity that will equal the whole (as the following example shows, it does not have to be 100%).
- Plot Remainder as Wedge and specify the color to represent the remainder.
- Labels tab, Format = Categories.
- Format = Decimal: 1000 and Decimal Places = 1.
Note: This graph uses 2 X columns of categorical data — one with the major categories (inner ring), the other with subcategories (outer ring). Constructing this plot requires a little extra effort. To see how it is made, press F11 in Origin 2020 and look for it by searching Graph Samples > All Plot Types for keyword = “2020”.
So, this is a broad rundown of the new doughnut and updated pie charts, for Origin 2020. Please look for these plots and more when Origin 2020 is released in the Fall of 2019.
Thank you for reading! | <urn:uuid:4966c24b-503d-4260-9b83-3679c2ac914a> | CC-MAIN-2022-33 | https://blog.originlab.com/pie-and-doughnut-charts-in-origin-2020 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.886948 | 771 | 3.21875 | 3 |
OTTAWA, ON (January 18, 2020): In an effort to improve Canada’s approach to the opportunities and challenges in the Indo-Pacific region, the Macdonald-Laurier Institute is launching a dedicated “Canada and the Indo-Pacific Initiative.”
This important new project will be led by Senior Fellow and Director of MLI’s Indo-Pacific Program, Jonathan Berkshire Miller.
“The true litmus test for the rules-based order will be its ability to evolve and withstand the challenges in the Indo-Pacific in the coming years,” explains Miller. “The COVID-19 crisis has only heightened these challenges and proven the need for Canada to develop a robust, comprehensive, and multipronged approach to the region.”
Up until this point, successive governments have failed to lay out a clear strategy for how Canada can develop a robust role in the Indo-Pacific. Yet the world’s future will likely be shaped in this crucial region.
On one hand, the Indo-Pacific contains four of the world’s five largest economies and over half of global GDP. On the other, it also plays host to some of the most significant challenges to the rules-based international order, including managing China’s rise, North Korea’s nuclear weapons program, tensions between India and Pakistan, conflicts over freedom of the seas, and much, much more.
According to Miller, the threats and opportunities emanating from the region present Ottawa with a compelling need to engage the region more substantively. “Through stronger collaboration with allies and partners, there is an opportunity to transform Canada’s role from one of a fair-weather partner to that of a regional power engaged on key economic, trade, security, and defence issues.”
MLI has long been the leading voice in Canada on rethinking how we engage partners like Japan, India, and Australia, as well as how we manage challenges from actors like China. In 2020 alone, MLI dedicated our annual dinner to the Indo-Pacific, hosted a webinar on the subject, released multiple papers and other publications, and was Canada’s most active voice in the national media on these issues.
“It is time for Canada to emerge as a Pacific nation, with Indo-Pacific interests across a range of security and prosperity issues that will hold major consequences in the lives of Canadians,” said Shuvaloy Majumdar, founder and program director of MLI’s Centre for Advancing Canada’s Interests Abroad. “Jonathan’s leadership on our Indo-Pacific Initiative will curate, elevate and advance a kind of collaboration that Canadian foreign policy has yet to benefit from.”
By further expanding our work into a dedicated initiative, MLI seeks to provide even greater guidance and clarity for policy-makers in search of a coherent approach to the region.
“The need for this initiative is self-evident,” argues Miller. “The future of Canada’s security, prosperity, and place in the rules-based global order will all be determined in the Indo-Pacific region. Canadians deserve answers as to how our government plans on proceeding, and MLI’s work will provide a framework for policy-makers as they navigate these issues.”
To learn more about this initiative, check out the full project page here. Furthermore, media are invited to contact:
Communications and Digital Media Manager | <urn:uuid:0ccdbddb-0c4c-4ed4-af9e-4b91489cc052> | CC-MAIN-2022-33 | https://macdonaldlaurier.ca/macdonald-laurier-institute-launches-canada-indo-pacific-initiative/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.925779 | 746 | 1.601563 | 2 |
First off there was the Aussie flu, followed by the French flu - and now the Japanese flu has made it these shores.
But how can you make heads or tail of them? What is the difference? And which one is worse?
Here, we have delved into the three to separate fact from fiction:
What is Aussie flu?
Experts in Ireland revealed on December 31 "less than 10 people" have died from the so-called 'Aussie flu' outbreak .
Doctors are now warning children - particularly those aged between five and 14 - could be most at risk.
Public health officials are urging people who are eligible for the free flu vaccination should "get it without delay".
Symptoms of Aussie flu:
- Sore throat and cough
- Muscle ache
- Runny nose and sneezing
Symptoms of Aussie flu are similar to those caused by normal flu, but they are more severe.
People should recover from normal flu within a week so, although the cough and fatigue may last longer.
So if you are still really ill after seven days, it is a good indication of something more serious.
Aussie flu can lead to pneumonia and other potentially fatal complications.
This year's flu vaccine has been developed to tackle the main strains which are circulating this season, including H3N2.
A number of strains of the virus, but particularly H3N2, led to Australia's worst flu season for nearly a decade.
The arrival of so-called Aussie flu comes as NHS England urged hospitals to defer pre-planned operations and routine outpatient appointments until the end of the month.
A subtype of influenza A, the bug mainly affects older people, those with long-term health conditions, pregnant women and children.
As flu viruses are constantly mutating, vaccines to protect against the disease have to change each season.
People are asked to take particular caution to spreading germs by washing their hands more often, covering their mouths and noses when they cough, and cleaning surfaces.
Dr Jillian Johnston told the BBC: "Getting the free flu vaccine is the single most important thing you can do to help protect yourself against flu.
"With high levels of flu activity in Australia during their winter, and the potential for similar here, it is more important than ever that everyone who is eligible gets vaccinated.
"We are fortunate to have a more comprehensive flu vaccination programme than Australia or England, but the benefits can only be realised if a high proportion of the groups who can get the vaccine actually take up the offer."
What is Japanese flu?
‘Japanese’ flu which is contracted and spread particularly by children has caused experts to urge parents to take up free jabs.
Yamagata flu is less severe but more contagious than Aussie flu.
Experts say this is because very young children are ‘super shedders’, meaning they excrete more of the virus because their immune systems can’t distinguish between what makes them ill and what will kill them.
As a result, children produce a stronger ‘transmission’ of the flu.
Unlike H3N2, protection against Yamagata is not included in the vaccine for over-65s or vulnerable patients, such as those with diabetes or respiratory disease.
Yamagata is a category ‘B’ strain of flu. Complications are less common and most people will recover within a week.
This means it’s less serious than Aussie strain, which is a category ‘A’.
And French flu?
Health workers are being urged to have the jab as the epidemic from across the Channel threatens to hit the UK.
Worryingly, figures show as few as one in three workers have been vaccinated at some hospitals.
NHS trusts are failing to get medical workers to have flu jabs amid the warnings that the French epidemic could spread to Britain.
The paper reports: “It comes amid a deepening NHS winter crisis, with 24 hospital trusts declaring ‘black alerts’ last week, as pressures threatened to overwhelm them, and thousands of patients stuck in ambulances outside hospitals as flu rates soar.”
It has been reported that around one quarter of NHS staff will contract flu during an average winter period.
The Sunday Telegraph reports that figures suggest around half will not show symptoms, which means they could remain in work and spread infections.
Warnings come after a study by Imperial College London which found every 10 per cent increase in NHS vaccination rates was linked with a 10 per cent fall in sickness absence.
What is the difference between flu and a cold?
The symptoms may be similar to a common cold, but flu tends to be more severe.
Flu tends to come on in a few hours, makes you feel exhausted and affects more than the nose and throat alone.
It can also lead to much more serious complications like pneumonia.
How can you protect yourself?
Flu is spread by germs from coughs and sneezes, which can live on hands and surfaces for 24 hours.
The flu vaccine is the best protection we have, though flu strains change so it needs to be done every year.
The flu jab is offered free to adults at risk, over-65s, pregnant women and children at risk aged six months to two years old, and a spray is offered to children up to four.
You can have the jab at your GP and some pharmacies - and it's still not too late to do so. Even though it's best to get vaccinated as soon as the flu vaccine is available, getting the vaccine later can still be helpful.
Even as late as January, there are still a few months left in the flu season, so it's still a good idea to get protected.
Serious side effects of the vaccine are rare.
Anyone can help prevent the virus from spreading by washing their hands regularly, covering their mouth and nose with tissues or a sleeve when they cough or sneeze, and cleaning surfaces they suspect are infected.
How can you treat flu?
Flu usually clears up by itself after around a week, but there are ways you can recover more quickly.
Rest, sleep, keeping warm, taking paracetamol or ibuprofen and drinking lots of water are all recommended.
GPs do not prescribe antibiotics as they will not relieve symptoms or help recovery.
You can seek advice most easily from a pharmacist, and are encouraged not to call 999 or go to A&E unless you develop sudden chest pain, have trouble breathing or start coughing blood.
Patients are advised to only go to their GP if their symptoms fail to improve after seven days, they are a child, over 65, pregnant or have a long-term medical condition or weakened immune system.
What are the experts saying?
Experts have warned that this year's strain of Aussie flu could be more dangerous than the 1968 flu pandemic that killed more than a million worldwide.
Public health expert Professor Robert Dingwall, of Nottingham Trent University, previously told BT.com it's "almost inevitable" that Aussie flu will strike Britain this winter.
He warned: "The reports from Australia suggest the UK might be in for the worst winter flu season for many years."
Professor Dingwall told the Daily Express that it could be the most serious outbreak of the virus since the pandemic 50 years ago.
But Public Health England said that it was not yet known whether the UK would be hit as hard as Australia. | <urn:uuid:5f469361-bf7f-4cc1-8aca-c5e928833fa4> | CC-MAIN-2022-33 | https://www.nottinghampost.com/news/health/what-you-need-know-foreign-1039612 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.970751 | 1,565 | 3.390625 | 3 |
Sinter Print and Concept Laser are two additive metal manufacturing units that are members of the ADAPT (Alliance for the Development of Adaptive Processing Technologies). There are various levels of membership to this consortium based out of Colorado and dedicated to the development of additive manufacturing technologies.
The levels of membership include the Tier 2, where these units can access the ADAPT database, and Tiers 3 and up, where they can access and direct the center’s research activities. Reaction Systems is a member company which creates new products and processes and turns them into commercial products. It recently won a contract extension from ADAPT for their latest project.
Reaction Systems, Colorado, was developing a hypersonic jet engine part for a Phase II Small Business Innovation Research (SBIR) project in association with the Air Force Research Laboratory (AFRL). They needed expert specialized additive manufacturing aid; which required developing a prototype of the part. ADAPT, and its additive materials characterization center guided Reaction Systems in the right direction.
Real-time additive manufacturing monitoring costs are skyrocketing, smaller units like Reaction Systems, are unable to cope with the expense. With ADAPT consortium, these manufacturers have access to the knowledge, resources, expertise, and peer organizations support which makes it feasible for units like Reaction Systems and Faustson to use the emerging additive manufacturing technology to complete their ventures.
The 3D printed prototype of Reaction Systems earned a certification with the support of ADAPT. The Reaction Systems SBIR project contract, worth $750,000, has been extended further for two years. Most of Reaction Systems’ work is done through the SBIR program. For example, the company devised a method of eradicating carbon deposits, to improve the performance of rocket engines. This has been possible due to the aid and guidance of ADAPT. | <urn:uuid:e1bb7190-6bba-4b26-8778-7990ff9cde53> | CC-MAIN-2022-33 | https://www.think3d.in/reaction-systems-project-gets-new-lease-of-life-thanks-to-adapt-initiative/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573876.92/warc/CC-MAIN-20220820012448-20220820042448-00072.warc.gz | en | 0.939247 | 385 | 1.960938 | 2 |
Xanax (also know by the generic name alprazolam) is a drug used to treat anxiety and panic disorder. Known for its ability to produce a calming, sedative effect, it is also highly addictive. Although prescription use can lead to dependence, it is even more dangerous when bought and used illicitly (“on the street”). If you have questions about Xanax, The National Rehab Hotline at 866-210-1303 can help 24 hours a day, seven days a week. Whether you need the names of local rehab centers, want to know what the warning signs of dependence are, or just need somebody to talk to, our staff members offer nonjudgmental support and guidance. Your calls are free and confidential.
What Does a Xanax Hotline Do?
Our hotline answers all kinds of questions about mental health and addiction, and Xanax use is a common topic. Like other addictive drugs, it disrupts the lives of its users and the people around them. When overwhelming feelings and cravings make it hard to know which way to turn, caring staff members can steer you in the right direction and suggest options for the recovery process.
Sometimes, it’s enough just to know you aren’t alone and help is available. The earlier the diagnosis and treatment, though, the greater the chances of success. If you’re ready to start the road to recovery, the hotline is a good place to start.
If you or someone else is experiencing the following symptoms, get help from a medical professional first, such as by calling 911, before calling the hotline:
• Extreme sleepiness or exhaustion
• Slurred speech or confusion
• Shallow breathing or slow heart rate
• Lack of coordination
• Dilated pupils
• Pale, cold skin
• Blurred vision
What Questions Do Helpline Operators Ask?
The role of a Xanax hotline is to help people who are battling Xanax dependence or addiction. Helpline workers know callers are anxious, and they’re trained to get to the core of the matter without causing further distress. They ask questions like these to get the information they need to assist a caller:
1. Is the person taking the drug a danger to himself or others? Is this an emergency?
2. What drug is being taken and for how long?
3. Are there other disorders, such as depression, bipolar disorder, a personality disorder, or PTSD, that complicate Xanax use?
4. Is the individual willing to enter a rehab center?
5. Is this the first time for treatment?
The more honest the answers to these questions are, the more help the hotline can provide.
What Questions Should Callers Ask?
Callers should be free to ask for information without being afraid of getting in trouble. Helpline staff usually stick to subjects they know well, including topics like these:
1. What are the dangers of Xanax addiction?
2. What treatments are available? Are they inpatient or outpatient? Are there local support groups?
3. What styles of talk therapy does rehab include? Does it include family therapy?
4. Where are treatment centers located?
5. Does insurance pay for rehab and detox?
6. Are other kinds of treatment options available?
7. Does the rehab facility treat co-occurring disorders?
8. Does the program include ongoing support after rehab?
Callers are usually stressed when they call for help, and it’s hard to remember all the information given to them. Having a pen and paper nearby to jot notes can prevent confusion later. It also helps to have a list of questions handy when the call starts.
What Makes Xanax So Dangerous?
Xanax belongs to a classification of sedatives called benzodiazepines, which includes several other drugs such as Valium. Doctors prescribe the drug to relieve generalized anxiety, panic disorder, insomnia, and stress. Although it is a highly effective muscle relaxant, it can have a rebound effect, causing symptoms to return with greater intensity after stopping the medication.
Common side effects include relaxation, euphoric highs, mood swings, forgetfulness, impulsiveness, and a lack of interest in sex. Physical effects include dry mouth, dizziness, fatigue, lack of concentration, nausea, vomiting, slurred speech, seizures, shortness of breath, erectile dysfunction, poor coordination, and tremors.
Xanax impairs the ability to drive and increases the risk of traffic accidents. It also makes falls and broken bones more likely.
Do I have a problem with Xanax?
If you become dependent on a drug, you need to increase the amount to get the same effect. You build up a tolerance and go through physical and mental withdrawal symptoms if you stop. If you’re addicted, you can no longer stop taking the drug even when it hurts you to continue. Addictions don’t always include physical dependence, but it’s common.
Patients who take prescription Xanax as recommended may still build up a dependence on the drug. Doctors usually advise patients to taper off the dose before stopping entirely.
What Are the Signs of Xanax Addiction?
As tolerance to Xanax develops, individuals taking a prescription require higher doses to get therapeutic benefits and avoid withdrawal symptoms. This can lead to intoxication and cravings even in patients who are taking it as prescribed. Watch for the following signs of Xanax addiction:
• Blurry vision
• Extreme drowsiness
• Difficulty in walking, lack of coordination, slurred speech
• Inability to stop or lower the dose
• Lies to get pills from doctors or acquaintances
• Compulsive purchase or use of Xanax
• Purchases of Xanax illicitly on the street
• Behavior that puts self and others at risk while intoxicated by Xanax
What Are Xanax Withdrawal Symptoms?
Xanax withdrawal symptoms usually get worse the longer the drug is taken. They can include the following mental and physical symptoms:
• Inability to concentrate
• Sleep problems
• Restlessness or anxiety
• Muscle spasms
• Rapid heart rate
• Fast, shallow breathing
• Convulsions (seizures)
• Depression and mood (anxiety, bipolar) disorders, or worsening of such problems that the person already has.
• Feelings of disassociation
• Panic attacks
What Causes Addiction?
Whether it’s a prescription or recreational use, the first dose of a drug is often by choice, but the path to dependence varies for each individual. Addiction changes the brain’s reward center in ways that are hard to repair.
When you participate in pleasurable activities, such as having a good meal or going to a ballgame, you feel good and look forward to doing them again. That’s because these activities trigger small bursts of dopamine in the brain. When you use alcohol or drugs to get high, however, the brain releases large surges of dopamine. Every time you get a rush, it takes more to get the same effect, and the substance use is no longer the thrill it was in the beginning. If you don’t use it, though, you have unpleasant withdrawal symptoms. It becomes necessary to use just to feel normal and avoid discomfort.
Substance use also affects the way the prefrontal cortex (a part of the brain) manages “executive functioning” skills (the ability to do everyday activities like get dressed, clean house, or run errands), and the brain no longer alerts the person to the consequences of impulsive behavior. Some drugs are more addictive than others, and that also plays a role in addiction. People metabolize alcohol and drugs differently, depending on factors like gender, age, and weight.
As the body gets used to the substance, it learns to process it more efficiently, and it needs larger amounts. One way of explaining addiction is saying that the cravings hijack the brain’s reward system, causing risky behavior and poor decision-making.
Do Interventions Work?
Approaching someone who has a Xanax problem is never easy, and it helps to be prepared. First, keep in mind that addiction changes the brain and makes it physically and mentally difficult to control behavior. It’s important to know the warning signs of use and overdose, check out treatment options, and make notes of incidents you notice that are related to the drug. Finally, think about the most effective way to share your fears and offer support. Interventions can be successful, but they may backfire if the person who has the addiction feels shamed or controlled.
Start by setting up a meeting with loved ones who can express their concerns and wanted outcomes without getting angry or frustrated. It’s usually a good idea to involve an addiction specialist, therapist, or counselor who knows how to set the tone of an intervention. If someone wants to be there but has trouble staying calm, consider asking for a letter that you can read in the meeting.
Be ready to act quickly if the individual agrees to get help, but also have a plan for what you’ll do if the intervention doesn’t work out. If that happens, family members may want to look for a support group for support and guidance. Another option is setting up a doctor’s appointment for the person with the addiction and asking for medical advice.
The next step is detox and medical management of withdrawal symptoms. Because withdrawal from Xanax is so intense, it usually takes place in a hospital or rehab center. Less severe cases of dependence may only require gradually reducing the dose or replacing it with a less addictive one while tapering the Xanax dosage.
Xanax Facts and Statistics
One danger of illicit Xanax is that its ingredients and strength are unknown, and sometimes they’re downright unsafe. In February 2021, a South Carolina newspaper reported multiple deaths and overdoses caused by fake Xanax. The fatalities included a man who used the dark web to buy supplies and find buyers for the fake pills, shipping them through the U.S. post office.
Even legally prescribed Xanax can cause harm. The following statistics indicate the scope of the problem:
1. Between 1996 and 2013, the number of people using Xanax and other benzodiazepines grew from 8 million to 14 million.
2. Doctors know it’s risky to prescribe painkillers and sedatives, but the number of combined prescriptions increased by 200% between 2001 and 2013.
3. Deaths from benzodiazepines increased by 400% between 2002 and 2015.
4. Between 2010 and 2014, over 3 in 10 opioid deaths also involved the use of benzodiazepines.
5. Overdose deaths are 10 times more likely to occur when benzodiazepines and painkillers are taken together.
6. Benzodiazepines can cause withdrawal symptoms for months or even years after the last dose.
7. Abruptly stopping benzodiazepines can cause convulsions (seizures) or sudden death.
8. Fake Xanax can contain fentanyl, an opioid that increases the risk of death by stopping your breathing.
9. In one study, 95% of hospital admissions for benzodiazepine also included other drugs.
10. Between 1990 and 2017, benzodiazepine overdose deaths among women increased by 830%.
Researchers are searching for better ways to avoid deaths from overdose, an effort that includes better public health education and training for consumers and professionals. In some states, government officials have put time limits on Xanax prescriptions to prevent overdose and addiction.
Get Help Now
Xanax addiction often occurs with other mental disorders, such as depression and PTSD, making it more difficult to treat both illnesses. However, treating both increases the odds of a successful recovery and lowers the risk of relapse. That’s why it’s important to find a treatment facility that uses an integrated approach to treat co-occurring disorders. If you’re ready to take the first step to recovery, The National Rehab Hotline can help you find resources for Xanax addiction treatment near you. Call us today at 866-210-1303. | <urn:uuid:c9dfd472-0189-4df8-b6c5-50a6731870ba> | CC-MAIN-2022-33 | https://nationalrehabhotline.org/benzodiazepines-addiction/xanax/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.928947 | 2,556 | 1.882813 | 2 |
Chocolate is not just easy on your taste buds; it may help keep you sharp mentally, too. Researchers in Italy have found that the flavanols in cocoa may improve mild cognitive impairment, the memory loss that often precedes dementia or Alzheimer’s disease.
Study participants drinking cocoa drinks with higher concentrations of flavanols had significantly higher overall cognitive scores compared to those whose drinks had a lower flavanol concentration.
The researchers didn't hand out candy bars. They assigned 90 older persons with mild cognitive impairment to drink 990 (high), 520 (intermediate), or 45 (low) milligrams of a dairy-based cocoa flavanol drink every day for 8 weeks. During the study, participants did not consume other sources of flavanols. The investigators used standard neuropsychological tests to evaluate cognitive function.
Scores significantly improved in the ability to relate visual stimuli to motor responses, working memory, task-switching, and verbal memory among those drinking the high- and intermediate-concentration flavanol drinks. Study participants drinking cocoa drinks with higher concentrations of flavanols had significantly higher overall cognitive scores compared to those whose drinks had a lower flavanol concentration. .
“I was somewhat surprised because it was a relatively small sample and, using well-established psychological tests. They found some pretty strong evidence that flavanols improve cognitive functioning,” Rachel Johnson, the Robert L. Bickford, Jr. Green and Gold Professor of Nutrition and a professor of medicine at the University of Vermont, told TheDoctor.
Johnson, who was not involved in the current study, says that she thinks the next step is repeating this study with larger samples and more diverse populations, and trying to determine just how flavanols work.
The Italian team suggest that flavanols may protect brain cells from injury, improving their metabolism, and their interaction with the molecular structure responsible for memory. Flavanols may also act indirectly by improving blood flow in the brain.
Foods that are rich in flavanols, such as tea, grapes, and red wine in moderation, are healthy foods. “I think it is certainly worth a try to fit these foods into a healthy diet,” says Johnson.
The study was published in the journal Hypertension. | <urn:uuid:659672ec-64b0-4c0f-b834-247300f3ce1c> | CC-MAIN-2022-33 | https://www.thedoctorwillseeyounow.com/content/aging/art3791.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.956858 | 465 | 2.8125 | 3 |
Researchers looked at more than 700 different baby foods.
Promotional claims on baby food products can be “misleading” and might “confuse” parents, academics have said.
Researchers said many baby food products have “healthy halo” promotional messaging on packs which might make parents believe that products are actually healthier than they are.
For instance some products labelled “vegetable tastes” actually have a higher proportion of fruit which are naturally more sugary.
Meanwhile claims of “no added sugar” may make parents believe that products are free from sugar.
Researchers from the University of Glasgow said that current UK legislation does not specifically regulate promotional messages used on commercial baby foods (CBFs) so they wanted to “understand the extent to which the baby food industry uses promotional claims on CBFs sold in the UK”.
They examined 724 baby products sold in Asda, Aldi, Lidl, Tesco, Sainsburys, Waitrose, Morrisons and Amazon between June and September 2020.
Their study, published in the Archives of Disease in Childhood, found that more than 6,200 promotional claims were made across the products including marketing messages, composition and nutrient detail and health claims.
Each baby food product has an average of nine promotional claims with one having 17 promotional claims on a single pack, the new study found.
“Promotional claims on CBF packaging are extensively used which could mislead parents,” they wrote.
Experts highlighted phrases such as: “The Government advises that you don’t need to wean your little one until they are six months. Every baby is different!” on products aimed at parents of babies aged four months and older.
Almost three quarters (72%) of products deemed to be snacks had promotional messages about baby-led weaning on them.
The authors wrote: “The ferocious use of marketing claims on CBFs reported here is in agreement with a WHO (World Health Organisation) report concluding the marketing of CBFs to be commonand pervasive.
“This is concerning since the availability of highly processed baby snacks is a rising trend and we found that dry foods (fingers foods and cereals) have a high number of health claims.
“Dry finger foods are given as snacks, however snacking is not recommended in this age group.
“Thus, the promotion of snacking habits as early as 6–12 months should be restricted because of negative implications for obesity.”
They added that phrases such as ‘first tastes’ or ‘vegetable tastes’ and/or nutrient claims such as ‘no added sugar’ could “mislead parents into perceiving that CBFs are free from sugars and get children accustomed to sweet tastes”.
And the term vegetable tastes “suggests foods are made of vegetables when in reality the ingredient contribution might be a combination of fruit and vegetables with a predominantly sweet taste”.
They warned that promoting baby foods which have a high amount of sugar could be “detrimental” as food preferences are often formed in early life.
Meanwhile the term ‘organic’ is used regularly and could influence parental trust, they added.
The authors wrote: “Promotional claims on CBF packaging are extensively used and, for the most part, unregulated. CBFs are promoted using ’healthy halo’ connotations that might confuse parents.
“Regulations on their use should be implemented to avoid inappropriate marketing.” | <urn:uuid:a3bc4b09-151f-4273-b300-22ffd9b9b546> | CC-MAIN-2022-33 | http://ruf.s33.xrea.com/promotional-claims-on-baby-products-misleading-parents-study/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.957266 | 737 | 2.34375 | 2 |
The article examines the impact of the COWID-19 pandemic on the financial system. The consequences and problems in some main areas of accounting are substantiated. The author notes that the impact of COVID-19 has led to a significant deterioration in economic conditions for many companies and increased economic uncertainty for others, and thus may be an event that may lead to a decrease in utility.
The COVID-19 outbreak and the risks associated with it have a material impact on companies’ accounting and financial reporting. At the same time, the impact is not limited to companies in the most vulnerable industries, as the impact on the economy is significant, and a high degree of uncertainty significantly complicates forecasting the future.
There are recommendations for further research and use in practice of specialists in accounting, control and taxation. | <urn:uuid:12d748d2-fbd1-40f5-b449-944b1541083d> | CC-MAIN-2022-33 | https://armgpublishing.sumdu.edu.ua/2020/07/14/prem-lal-joshi-member-of-the-editorial-board-of-financial-markets-institutions-and-risks-journal-wrote-an-article-about-covid-19-pandemic-and-financial-reporting-issues-and-challe/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.955707 | 164 | 1.835938 | 2 |
It’s called Slim Rice, but is not made with any kind of rice.
It’s made of water and konjac root.
There have been other rice-substitution products made since.
What is Slim Rice?
Slim Rice is a brand made by the British company Eat Water promising to be a zero-carb, gluten-free substitute for basmati rice to help you lose weight by suppressing your appetite. It is made only of water and konjac root. Eat Water also makes substitute spaghetti and penne.
Cooking with Slim Rice
Slim Rice comes ready cooked, so you do not have to wait for it to boil. It’s packed in water.
Open the pouch into a strainer.
Don’t use a colander, since the holes will be too big for rice-sized pieces.
Rinse well with cold water to remove the smell. You can then heat in a microwave for one minute or heat in a pan for one to three minutes.
By itself, Slim Rice is practically tasteless.
It does absorb flavors from other foods, making it a low-calorie and gluten-free addition to a stir-fry, curry, soup, risotto, or just about any other dish where the rice is completely soaked by a broth or sauce.
Advantages of Slim Rice
One advantage to Slim Rice is that it cooks quickly. You don’t have to wait around for 20 or 30 minutes for it to boil.
Slim Rice even cooks faster than bags of ready-cooked frozen rice that you heat up in a microwave.
Another advantage is that it is much lower in calories than regular basmati rice.
A 3.5 ounce (100 gram) serving of basmati rice is 350 calories. A comparable serving of Slim Rice is only 7.7 calories.
Diabetics are always concerned about spikes in their blood sugar levels after they eat.
Since Slim Rice is low in calories and carbohydrate-free, there is relatively little to cause any rise in blood sugar.
What you add to the rice could still cause a rise in blood sugar.
Slim Rice is supposed to help curb snacking, which could lead to spikes in blood sugar.
Arguably, the main advantage of Slim Rice is that it fills you up.
This is because konjac root quickly absorbs water and swells up. Once it’s in your stomach, it swells out to fill you up.
This is how Slim Rice and its sister product Slim Pasta got its name. “Slimming” is the UK word for “dieting.”
It’s not named because the rice is thinner than ordinary rice.
Uses of Konjac Root and Choking Hazards
The only other ingredient than water in Slim Rice is the root of the konjac plant (Amorphophallus Konjac).
This is a plant that grows in Asia. Unlike many other kinds of edible roots like potatoes or yams, konjac does not contain any carbohydrates.
It does contain fiber, which makes it the main ingredient in the dietary fiber supplement glucomannan, also known as konjac glucomannan or KGM.
It’s used for constipation, diabetes and high cholesterol.
It’s been used in Traditional Chinese Medicine (TCM) mainly by making the powdered root into a gel.
It’s been used to treat everything from coughs to tumors.
However, there haven’t been a lot of clinical studies showing if these treatments are effective.
Studies that have shown KGM is effective in these areas:
- Reduce phlegm production.
- Lower cholesterol in the plasma.
- Improves the body’s ability to metabolize carbohydrates.
- Makes you have bowel movements regularly.
Konjac root powder being used as food is nothing new.
It’s been used by food manufacturing companies for years as a thickener, since it does not have any taste to clash with the other ingredients.
It’s also used as flour, tofu, gelatin, candy, drinks, shirataki rice and shirataki noodles.
They are also sometimes used to make the “bubbles” in bubble tea, but usually the bubbles are made with tapioca.
Unfortunately, solid capsules or pills made of konjac root and some candies have been a choking hazard.
Some candies and noodles made of konjac root have been banned in some countries.
However, Slim Rice has not been banned and has not proven to be a choking hazard.
Any kind of rice, no matter what it is made of, can be a choking hazard for children under one year old.
Problems with Slim Rice
Besides it’s lack of taste and unusual smell when you open up a packet, Slim Rice has come under fire by nutritionists for its almost complete lack of nutrients. Slim Rice is 97% water.
The National Obesity Forum states that you don’t do your body any good by eating heavily processed diet foods, since you are not eating the nutrients you need to stay healthy.
They recommend that instead of Slim Rice, eat a small portion of brown rice or whole-wheat pasta.
Since brown rice and whole-wheat pasta has a taste, you need to use less sauce or other ingredients that you need to make Slim Rice somewhat edible.
Brown rice contains not only carbs, fiber and fat, but protein and three kinds of B vitamins.
Whole-wheat pasta contains carbs, protein, zinc, magnesium and iron.
Frequently Asked Questions About What is Slim Rice
Does Slim Rice Taste Like Rice?
Slim Rice does not have much of a taste at all since it’s mostly made of water. It is chewier than rice.
What Does Slim Rice Smell Like?
When you open up a packet of Slim Rice or Slim Pasta, it usually smells like rubber or starch. Slim Rice needs to have the water in the packet drained. Then, rinse well in cold water to remove the smell.
Is Slim Rice Good for Weight Loss?
Slim Rice can keep you feeling fuller for longer, so you can curb snacking. However, you still need to diet and exercise in order to lose weight.
The Least You Need to Know
Slim Rice gets is supposed to be a basmati rice substitute for dieters.
It’s made of 97% water and konjac root. Many people complain that it has no taste at all, and has a peculiar texture.
Nutritionists claim that Slim Rice does not provide any healthy nutrients.
Although water is good for you, it’s not good to have a diet mostly consisting of water. | <urn:uuid:cd81a041-c8cb-4776-aff4-d9a8aeb5bfba> | CC-MAIN-2022-33 | https://foodandfizz.com/what-is-slim-rice/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.944989 | 1,434 | 1.773438 | 2 |
Synthesis ofwater-compatibleimprintedpolymersof in situ produced fructosazineand2,5-deoxyfructosazine
Fructosazine and 2,5-deoxyfructosazine are two natural chemicals with various applications as flavoring agents in food and tobacco industry; the 2,5-deoxyfructosazine has also anti-diabetic and anti-inflammatory activities. In order to quantify these compounds in natural samples such as plant or food, we have developed a selective technique based on a water-compatible molecularly imprinted polymer (MIP). MIPs are prepared with a covalent approach from 2,5-deoxyfructosazine as template formed in situ by the self-condensation of glucosamine with vinylphenyl boronic acid, taken as catalyst and covalent monomer during the pre-complexation step. Acrylamide and polyethylene glycol diacrylate are used as supplementary non-covalent functional monomer and cross-linker, respectively. For the first time, a highly cross-linked but highly polar imprinted polymer of fructosazine and deoxyfructosazine is obtained as a solid material and not a gel. Amount of monomers is optimized to obtain high selectivity for both molecules. Results show that the MIPs prepared have a significant imprinting effect with a resulting imprinting factor of 3 for both templates. Molecularly imprinted solid-phase extraction is then performed and could be used in routine analysis to extract 2,5-deoxyfructosazine and fructosazine from soy sauce. | <urn:uuid:45dbadc6-650c-4ed9-89a6-5396251c99c5> | CC-MAIN-2022-33 | https://chemaxon.com/publication/synthesis-ofwater-compatibleimprintedpolymersof-in-situ-produced-fructosazineand25-deoxyfructosazine | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.935043 | 338 | 1.648438 | 2 |
- The 1st renewable energy auction of Colombia is to be held in October 2019 as per the revised schedule issued by the government
- Along with solar, other participating technologies in the auction are wind, geothermal, small hydro and wave energies
- Projects with 5 MW of capacity or more will be eligible to compete under the auction and winning projects will be required to supply specific amount of electricity during 3 separate blocks of time
- Interested bidders will submit their offer of specific amount of electricity to the UPME which will then compile offers and determine maximum capacity to be auctioned
Colombia plans to hold its first full-fledged renewable energy auction in late October 2019, announced its Ministry of Mines and Energy. The heartening news comes after the government scrapped the previous auction in February 2019 citing antitrust rules, after the 500 MW tender was oversubscribed receiving 1.5 GW of bids (see No Winners In Colombia RE Auction).
Solar is one of the participating technologies along with wind, geothermal, small hydro and wave energies. Renewable energy projects with 5 MW and more capacity will be eligible to enter the competition and should be able to supply specific amounts of clean power during 3 separate blocks of time.
Market intelligence firm Enerdata says the 15-year power purchase agreements (PPA) determine that buyers will pay for the amount of electricity contracted and not for its withdrawal.
It further adds that the Energy Mining Planning Unit (UPME) of the South American nation will compile offers from generators and announce the maximum capacity to be auctioned and setting a minimum limit to be purchased. Ahead of the auction, a maximum price will be fixed.
Names of shortlisted candidates will be published by September 24, 2019 and winners announced on October 22, 2019.
Details of the auction timeline and other specifics are available on the website of the UPME.
In the previous auction terms launched in January 2019, the country offered 1,183,000 MWh of clean energy deployment annually for which it finally received 1.5 GW worth of bids (see Colombia Gets 1.5 GW Bids For First RE Tender).
In March 2019, Wind Energy and Electric Vehicle Review reported that Colombia’s Energy and Gas Regulatory Commission and XM Company Market Experts auctioned 1,398 MW of renewables under its Reliability Charge Auction with a validity period of 2022-23 with solar securing 238 MW (see 1.39 GW Wind/Solar Awarded In Colombian Auction). | <urn:uuid:6bd649c7-e885-40f6-af8c-e7689a06efb4> | CC-MAIN-2022-33 | https://taiyangnews.info/markets/colombias-1st-re-auction-scheduled-for-oct-2019/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.953063 | 504 | 1.742188 | 2 |
Advancing health equity is one of the five strategic objectives the CMS Innovation Center (CMMI) outlined in its Strategy Refresh back in November 2021. It’s no surprise that health equity is becoming an increasingly important goal at CMMI as the Biden administration has made health equity a major priority since day one.
However, CMMI has its work cut out for itself. According to a July 2022 report, implicit bias is pervasive in at least three payment models, which signals challenges if CMMI is serious about advancing equity.
Implicit bias is an involuntary bias that a person is unaware of. Often times, negative attitudes and stereotypes can play a powerful role in shaping implicit bias, or “unconscious prejudice.” Two top CMMI officials authored the report on implicit bias to analyze how implicit bias may be impacting beneficiary groups in payment models.
In its analysis, CMMI only reviewed three models: the Comprehensive Care for Joint Replacement (CJR) Model, Kidney Care Choices (KCC) Model, and Million Hearts® Cardiovascular Risk Reduction Model. CMMI selected these models because they represent a microcosm of CMMI models that vary by mandatory/voluntary status, financial methodology, and risk stratification.
Overall, the report found that use of certain risk-assessment and screening tools, provider tools, and payment design and risk-adjustment algorithms has led to the exclusion of some beneficiaries from these models. Here are some key findings:
- The CJR Model tests bundled payment plans for participating providers that perform knee and hip replacements. The report found beneficiaries receiving joint replacements were “less medically complex” than those receiving joint replacements at the same hospitals before model participation began. The report also found that beneficiaries in the model are less likely to be dual-eligible, which indicates a lower socio-economic status. It is also worth noting that Black Americans are likely to receive knee and hip replacements than White Americans.
- The KCC Model encourages nephrologists, dialysis facilities, and end-stage renal disease (ESRD) practices to focus on the total care of their patients and incentivizes kidney transplants for chronic kidney disease beneficiaries. The analysis found that the model’s medical eligibility criteria may have inadvertently excluded Black American beneficiaries, despite the fact that Black Americans are over three times more likely to have ESRD.
- The Million Hearts Model provides financial incentives for practices to lower 10-year cardiovascular disease risk for the 30% of high-risk Medicare beneficiaries. The evaluation found that despite being developed specifically for Black and White populations, the risk calculator used to predict risk scores underestimated risk among patients in other racial and ethnic groups that do not identify as White or Black as well as patients in lower-income households.
CMMI acknowledged that its findings are “troubling” and underscore a need for a “more systematic evaluation of implicit bias in current and new models.” As a next step, CMMI says it is working on a “step-by-step guide” to detect and address bias in current models and prevent bias from forming in future one.
While it’s encouraging to see CMMI has a plan to address implicit bias, the revelation that unconscious prejudice is prevalent in three key payment models only adds to the list of challenges CMMI needs to address. According to an August 2021 report, only a handful of CMMI’s 40-plus models have met the center’s statutorily required goal of reducing costs or improving quality. In addition to the Biden administration’s emphasis on health equity, the report’s findings likely catalyzed CMMI to lay out its strategic refresh in November 2021, which makes reducing costs and improving quality its “overarching goal.” On top of CMMI’s difficultly of meeting its statutory obligations, the center now faces the challenge of addressing implicit bias, which may also be prevalent in additional payment models.
All in all, CMMI’s issues with reigning in costs, boosting quality, and stopping implicit bias could signal larger structural problems within the center. Of note, CMMI’s problems are not lost on lawmakers, in May 2022, Sen. Cory Booker (D-NJ) and Rep. Terri Sewell (D-AL) introduced bicameral legislation to require the center to work with experts on health equity when developing and reviewing payment models.
At least CMMI has acknowledged its challenges and is laying out plans to address them, including its strategic refresh and a forthcoming “step-by-step guide” on tackling implicit bias. However, CMMI won’t be able to solve its problems overnight, and the center has a long way to go if it not only wants to achieve its statutory goals of bringing down costs and enhancing quality, but also take on new priorities like improving health equity. | <urn:uuid:7815dccf-adf4-4840-9618-0c7170e3957b> | CC-MAIN-2022-33 | https://chamberhill.com/tag/implicit-bias/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.948329 | 997 | 1.914063 | 2 |
A One Affordable Plumbing has been happily serving the Robin Glen-Indiantown, Michigan city for years. Our service technicians are experts in the complete series of pipes solutions. Whether you or a person in your family wants pipes solutions, the friendly as well as experienced staff of 24 hr Emergency Plumbers will certainly make sure that you are totally notified as well as comfortable with any kind of treatment or service that you choose.
Swimming Pool PlumbingThe pipes network is the pillar of your pool. The quality of your pools absolutely depends on their plumbing foundations. Pool Pipes consists of the pipes as well as fixtures for the distribution and also disposal of swimming pool water.
Swimming pool Plumbing responsible for the working of all the departments of your pools, such as swimming pool filtration, pool cleaning, chlorination systems, falls, pool/spa home heating, health club jets/air, skimmers, aerators, car water-levelers, drains/returns.
Swimming Pool Plumbing mainly includes the flitting of pumps, pipes runs, car water levelers, filters, gas heating systems, as well as chlorinators. Your pumps are the resource of water for your pools.
Your plumbing runs price depend upon the size of your pipes runs; more the size, even more you'll be paying. Your swimming pool run foundations hold the main secret in getting the very best swimming pools. have to set up best possible ways to obtain reliable outcomes.
The Auto Water Levelers (AWLs) of your pools are used the pipes that are used to fill your pools. Usually, 3/4" PVC connections are used to connect AWLs. When the water level dips listed below a particular degree, automobile Water Levelers are the devices that check the water degree of your pools and instantly fill up your swimming pools.
You could put your heating units the locations best fitting to your pools, yet your heating units had to be at least 4 feet from any type of home line. According to the U.S. state codes, the exhaust duct of the heater device should be 4 feet from any type of residential property line. The unit itself could be within the 4 foot limit, however not the exhaust duct.
gobble the leaves and also various other particles floating at the surface area of the water of your swimming pools. Skimmers are mounted right at the water lines so that at normal degrees, the swimming pool water has to do with halfway up their mouths. The remainder of the debris calms down to the bottom where your swimming pool vacs could suck it up. The main drains are linked to the bottom of the skimmers. The drains are mainly utilized to offer sufficient water from the pool for purification. Usually 2" PVC are utilized in all skimmer pipes. These include the runs from the tools to the skimmers and from the skimmers to the main drains.
The pipes that return filtered water back to the pool are called returns. The water "drew" from the swimming pool through the pool vac and/or the skimmer/main drains experiences the filter as well as returns the swimming pool equally distributed with these return pipes. Nowadays, knotted returns are run by a lot of pool plumbers to offer also water circulation distribution; this is called an Anti-Vortex drain.
Pool Pipes solutions are offered by several professional swimming pool companies. There are a variety of specialist swimming pool firms operating throughout the states. Some companies additionally do use their solutions in bundles that normally consist of HP Hayward Pumps, Sand, DE, or Cartridge Filtration Solutions, Swimming pool Vac Cleansing Systems, 15' Plumbing Runs, Car Water Levelers, and also Requirement Chlorination Systems.
Swimming Pool Pipes consists of the pipelines and components for the distribution and disposal of pool water.
The Automobile Water Levelers (AWLs) of your pools are tapped into the pipes that are used to load your pools. Vehicle Water Levelers are the gadgets that keep an eye on the water degree of your swimming pools and also instantly load up your swimming pools when the water degree dips below a specific level.
The water "sucked" from the swimming pool using the pool vac and/or the skimmer/main drains goes via the filter and returns the pool equally distributed through these return pipelines. Swimming Swimming pool Pipes services are used by several professional pool companies.
Water Heater Installation Near Robin Glen-Indiantown, Michigan
How To Hire A Plumbermany people require a plumbing professional for their existing pipelines when something breaks. This typically happens at a bothersome time as well as frequently necessitates an emergency phone call to deal with the problem swiftly. Costs for this could be high so there are several things consider before working with one.
repair, hire a plumber that focuses on fixing. It is always important to obtain multiple bids on your job, however in an emergency situation this could not be possible. Ask just what the expenses will certainly be in advance, including any after hrs or emergency service fees. works with a hourly basis, figure out in advance just how the time is computed as well as keep an eye on the amount of time spent.
Talk about the range of job with the plumbing technician so you are familiar with the kind of work that requires to be done and also exactly how it might impact existing systems. If you really feel a plumber is boosting the extent of work unnecessarily, do not pick them for your job.
Plumbing professionals should be accredited so ensure you have their license number as well as validate it. If the plumbing is bidding on the project, there should be one rate for the whole work. If a plumbing functions by the hour, the hourly rate must be clearly identified along with any type of additional costs.
Working with a plumber for brand-new construction enables you to take a little bit more time in the employing procedure. Examine references as well as interview plumbings. Request recommendations from trusted resources.
If you need a plumbing technician in an emergency scenario; nonetheless, you will have to get information a lot a lot more swiftly. You might not have time to check around before picking a plumbing.
If you are looking for repair work, employ a plumbing that specializes in repair. If the plumbing technician works on a hourly basis, discover out up front exactly how the time is computed and keep track of the amount of time invested.
Review the scope of work with the plumbing so you are acquainted with the type of work that needs to be done as well as just how it could influence existing systems. If you feel a plumbing is raising the scope of work needlessly, do not pick them for your job. If a plumbing professional functions by the hour, the per hour rate needs to be plainly determined along with any extra fees.
24 hour Emergency Plumber Services in Robin Glen-Indiantown, Michigan | <urn:uuid:619d205f-5fce-4e10-afa6-d13146e90933> | CC-MAIN-2022-33 | https://www.aoneaffordableplumbing.com/water-heater-installation-robin-glen-indiantown-mi/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.959531 | 1,433 | 1.5 | 2 |
By Adrian Lomax
The guard stood in the middle of the seg unit, counting, 26 of the 40 cells had the 3x12 inch Plexiglas windows in the cell doors covered with paper form the inside. The 5:00 PM count approached, and the guard knew that if the prisoners kept their windows covered so that they couldn't be seen, the Lieutenant would order the guards to suit up in riot gear to forcibly enter each of the 26 cells to remove the window covering.
The turnkey walked back to the control booth, shaking his head. Five hours and 26 "cell extractions" later, the second shift guards were tired and mad. They put in a lot of work that day.
The whole ordeal could have been averted had the sergeant not decided to cancel use of the segregation law library that evening, apparently for no reason other than to avoid the work involved in escorting prisoners to and from the small room containing law books. In protest 26 of the seg unit's prisoners decided to "make 'em suit up."
From November to June, I as confined in the disciplinary segregation unit at Wisconsin's Racine Correctional Institution. During that period the prisoners there engaged in numerous collective protest actions in response to mistreatment by the guards. The convicts' weapon was their won solidarity combined with the laziness of prison guards. Turnkeys don't mind suiting up on one inmate, but when they have to perform 15 or 20 cell extractions during one shift, they think twice the next time they consider doing something likely to cause the prisoners to revolt.
The convicts' tactics involved mass flooding of cells, refusing to return meal trays, throwing meal trays off the tier, and the trusty covering of cell windows. On two occasions the full complement of prisoners in the outside recreation cages refused to come inside.
The guards frequently sprayed prisoners with mace and other chemical irritants during cell extractions. In those cases prisoners would try to yank the gas masks off the faces of as many guards as possible when guards entered the cell, exposing them to the chemical agents.
After each cell extraction, guards put the prisoner in a shower stall, allowing him to wash off the chemical agents, removed all property from the cell, cleaned up the chemicals, then put the prisoner back in the cell on "strip cell" status, with no property, no clothing, and no sheets, towels, or blankets. Under Wisconsin law, strip cell status may last no more than three days, but in practice it often lasts longer because it's difficult to get the guards to return one's property. On some occasions, guards' refusal to return prisoners property after three days in strip cell status set off a new round of protest.
At one point prisoners began refusing to stick their hands out to be cuffed while they were in the shower stalls following a cell extraction, bringing a forcible extraction from the shower stalls. Guards responded by refusing to remove handcuffs and leg irons while the prisoners were in the showers. Turnkeys would cut prisoners' clothes off with scissors, put them in the shower stalls in restraints, and remove the restraints only after the prisoners were returned to their cells.
Something that's common in segregation units is guards who act like macho tough guys, continually disparaging prisoners, confident that, since they work in seg, not prisoner will ever be able to lay hands on them. At Racine, Lieutenant Ron Molnar is the archetype of that character. Walking around with his chest stuck out, scowling and shouting insults at convicts, Molnar appears to believe he's John Wayne.
Shortly before I was transferred from Racine, a prisoner named Ervie Gray refused to come in from the recreation cage. Molnar got five guards suited up in riot gear to "extract" Gray. When the goon squad came out of the building, Gray climbed the chain link fence, braving the razor wire, and climbed to the ceiling of the seg building.
After being sprayed with chemical agents, Gray eventually decided to come down. When he started climbing down the fence, however, Gray didn't climb down the side that would have left him inside the rec. cage. Instead, Gray climbed down the side of the fence that put him in the common area, along with Molnar and the other guards.
Upon seeing Gray climbing down the outside of the fence, tough guy Molnar immediately ran into one of the rec. cages and pulled the door shut behind him! Even with five guards standing by in riot gear, Molnar wanted to take no chances on Gray getting hold of him.
I'm now confined in the seg unit of the Green Bay Correctional Institution. There isn't the same kind of solidarity among the prisoners here, so collective protests aren't the order of the day. But that's subject to change.
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Already a subscriber? Login | <urn:uuid:27cef816-2c5d-4452-8ac8-9aa2084ffdac> | CC-MAIN-2022-33 | https://www.prisonlegalnews.org/news/1993/nov/15/report-from-the-hole/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573876.92/warc/CC-MAIN-20220820012448-20220820042448-00072.warc.gz | en | 0.971151 | 1,025 | 1.953125 | 2 |
The Different Types of Semi-Trucks & Trailers
If you’re considering a career as a truck driver, you might be surprised to find out how many types of trucks and trailers there are — and corresponding types of trucking jobs.
1. Flat Roof Sleeper
This type of truck has a sleeping compartment for drivers and is larger and more expensive than other semi trucks. Compared to mid-roof and raised-roof sleeper trucks, flat roof sleeper trucks have the least amount of headspace.
2. Mid-Roof Sleeper
These units may have a bed, storage compartments, and even a TV. Mid-roof sleeper trucks have a rounded and slightly higher roof than flat-roof sleeper trucks. Drivers have extra room to rest in the truck during breaks.
3. Raised-Roof Sleeper
The roomiest of the roof sleeper trucks, the raised-roof sleeper may have a side-storage tower and an additional 12-18 inches of space, compared to mid-roofs.
4. Day Cab
Day cabs are used to deliver loads during the day for routes that require no more than one day of travel. The trucks are typically smaller and less-expensive, compared to other semi-trucks. They have less space for drivers and fewer axles.
5. Slope-Nosed Truck
These trucks have a short, rounded front and are able to haul heavy loads and longer trailers. Slope-nosed trucks are better able to endure bumpy roads.
6. Conventional Nose Truck
This type of truck is less common today, due to its low fuel mileage. However, they were designed for easy access to the diesel engine.
Types of Trailers for Semi-Trucks
Semi trucks may be outfitted with the following trailers:
- Box or dry van trucks
- Dry bulk cargo trucks
- Dump or tipper commercial trucks
- Flatbed trucks
- Lowboy semi-trailers
- Refrigerator and reefer semi-trucks
- Tanker or fuel trucks
How To Choose The Right Truck
If you’re considering purchasing a truck, be sure to consider what kinds of jobs you’d like to do — one-day deliveries or longer ones? What geographical areas will you be driving in? If you plan on driving through mountainous regions, you’ll need a semi-truck with extra gears to prevent an accident. Other factors to consider include horsepower, transmission type, fuel efficiency, and resale value. | <urn:uuid:1f5e5472-1d97-4f4c-962b-c5d4d069a130> | CC-MAIN-2022-33 | https://www.americatruckdriving.com/the-different-types-of-semi-trucks-trailers/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.946092 | 537 | 1.703125 | 2 |
The CEO says by the middle of next year, 1m Teslas will be on the road that are fully capable of driving themselves
SAN FRANCISCO • Tesla Inc’s calling used to be bringing affordable electric cars to the masses. Elon Musk is now ripping up the script, vowing to pair self-driving technology with a sharing service that will make it crazy for consumers to buy other cars.
The CEO said by the middle of next year, one million Teslas will be on the road that are fully capable of driving themselves. During an hours-long investor day presentation focused on autonomy, Musk said customers will be able to put their cars onto a shared network of robotaxis, which will be able to get around without a human inside.
Even for Musk, 47, who’s never shied away from outlandish predictions, the timeline is hugely ambitious. Alphabet Inc’s Waymo, widely thought to be a leader in the autonomous space, has shied away from letting its autonomous vehicles roam without safety drivers. But with Tesla facing mounting concerns about demand for its electric cars, the CEO said both the company and its customers will reap major monetary benefits once self-driving robotaxis are ready for prime time.
“The fundamental message that consumers should be taking today is that it’s financially insane to buy anything other than a Tesla,” Musk said on Monday at Tesla’s headquarters in Palo Alto, California. “It will be like owning a horse in three years.”
The catch for Tesla investors is that all this is going to be costly in the near term. When asked how much autonomous technology is costing Tesla, Musk responded: “It’s basically our entire expense structure.”
Whereas Tesla has said in the past that it expects to be cashflow positive in every quarter beyond the first three months of this year, Musk now said the goal is to be cashflow neutral, while it’s building up a fleet of self-driving vehicles that will make their way into the robotaxi service.
“Between now and when the robotaxis are fully deployed throughout the world, the sensible thing for us is to maximise the number of autonomous units made and drive the company toward cashflow neutral,” Musk said. “Once the robotaxi fleet is active, I would expect to be extremely cashflow positive.”
On Monday, Tesla shares ended the day down 3.8% at US$262.75 (RM1,085). While they briefly rose as much as 0.4% in late trading, they ended the post-market session little changed. The stock has declined 21% this year.
For years, the promise of Tesla hinged on bringing a US$35,000 Model 3 sedan to the mass market. Earlier this month, Tesla made it impossible for customers to order that version of the Model 3 online. Customers who choose to lease a Model 3 aren’t going to be able to buy the car at the end, as leased cars will be ultimately used in the company’s network.
When one analyst told Musk that it sounded like Tesla was making a massive balance-sheet commitment to autonomy and asked about the company’s financing strategy, the CEO dropped a hint that a fundraising may be in the offing.
“It would be difficult to talk about financing rounds in this venue,” he said. “I think we’ll make the right moves. I think we’ll make the moves you think we should make.”
Roughly 100 analysts and investors attended Tesla’s event in person and took Model 3 test drives afterward.
“It was a curated route, and it did a great job,” said analyst Gene Munster of Loup Ventures. “It showed me that Tesla has made a lot of progress. If you were there in person, it was hard not to drink the Kool-Aid. They’ll capitalise on this to raise money, and that de-risks the business.” — Bloomberg | <urn:uuid:1ed29310-7bab-442b-a727-07d82e8a1409> | CC-MAIN-2022-33 | https://themalaysianreserve.com/2019/04/24/musk-makes-self-driving-technology-teslas-costly-new-calling/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.961452 | 853 | 1.726563 | 2 |
Advanced Nursing studies at any good Australian campus demands exquisite research skills to complete numerous Nursing assignment tasks with originality and stout academic proficiency. Only the best content based on ethical nursing practices and accurate citations and that too when submitted within the deadline; will fetch you a high distinction.
You are not alone in this though. That is exactly what a nursing student feels like amid all assignment pressures. Trust us! We would be raking in riches by now if we could get a dime every time when a student says, “Can you Do My Nursing Assignment for me” or “Can I pay someone to write my Nursing Research Proposal?
Hire the best and most affordable Nursing Assignment Experts at My Assignment Services.
Nursing as a subject that deals in encompassing of comprehensive health promotions, prevention of diseases, and taking holistic care of people who are physically and mentally ill. It also incorporates promotions and advocacy for a safe surrounding to help the community thrive. Our Nursing assignment help experts, who provide academic assistance through guided sessions, have enabled many students to gain an in-depth understanding of the nursing policies to manage the community healthcare system efficiently. According to many nursing assignment experts, nursing is a profession that focuses on helping improve the holistic wellness of a society or a community. That is why nursing is an important subject in the eyes of every university and online nursing assignment help experts who provide academic assistance through guided learning sessions as well. The below info graphic talks about the components present in nursing.
Nursing Course Overview by Nursing Assignment Writers
Our Australian nursing assignment help experts who provide academic assistance through guided learning sessions say that Nursing as a subject offers several opportunities to discover the theoretical and practical concepts of health and disease within the community. If you have undertaken Nursing for your higher studies, you will be able to develop a comprehensive range of skills that include critical thinking, rational decision making, and effective communication. You will be able to develop your skills by usage and application of simulators, clinical sets of equipment and audio-visual aids, etcetera. Undertaking a nursing assignment help through guided sessions, students learn more about their subject as it requires an in-depth analysis of the entire subject and its scope.
Our nursing assignment helper who provides academic assistance through guided sessions, regards Nursing as a vast subject that involves learning a lot of theoretical concepts and training of practical skills. Nursing is important because it is concerned with the general welfare of the community as a whole. This is the reason why prominent universities worldwide put special emphasis on nursing assignments, making several students reach out to “do my nursing assignment” search queries online. The course is usually devised in such a way that students are able to grasp the entire subject thoroughly. However, the same is not always the case with nursing assignments. Nursing assignments are an important part of the nursing curriculum and because nursing is such a vast subject, the assignments are often complex and lengthy. Hence, students prefer to get their assignments done by nursing assignment writing services experts.
Students prefer taking nursing assignment help online through guided sessions from subject matter experts because they don’t want to spend too much time writing down these assignments. Students are often burdened with multiple projects, exam preparation and at times doing part-time jobs to ease off their student debt, therefore, they are often unable to complete their assignments on time.
A stellar nursing assignment writer understands the university requirements and the marking rubric to deliver impeccable assignments free from grammatical errors, typographical errors and plagiarism. That is why we encourage you to go for the best assignment help in Australia through guided sessions.
There are many topics inside the syllabus, which our online nursing assignment help experts who provide academic assistance through guided learning sessions are well aware of. As a nurse, you need to perform various tasks depending on the area you specialise in. The following info graphic explains the responsibilities of a nurse.
Nursing Assignment Topics
As discussed earlier, nursing is a complex and vast subject. It is continuously growing with upgrades in medical science and medical instrumentations & technology. There are a number of students who get stuck with their assignment and searches “is there someone who can write my nursing assignment?”. They can take help from My Assignment Services.
- Nursing Ethics: It is a branch of ethics that specifically deals with medical ethics and principles like beneficence, maleficence, and reverence for autonomy. If you are confused in any topic and need help with nursing assignment, we have tutoring services for you as well.
- Mental Health: It involves providing care to patients with mental health issues.
- Behavioural Health Nursing : This deals specifically with human behaviour, personality and emotions.
- Maternal and New Born Nursing Medico-legal It involves the study of various regulations, laws and policies mandated by nursing regulating authority of a country. Only the best nursing assignment help experts who provide academic assistance through guided learning sessions can guide you in this topic.
- Pharmacology This deals with the understanding of the effects of different drugs and how it affects the human body along with its side-effects.
- Physiology It deals with the scientific study of bodily mechanisms and its co-relation with the life system. Nursing assignment mostly include concepts from this topic/section.
All these different specialisations come with their own set of assignments that focus on bringing out a student’s understanding of nursing as a subject, its applications and the responsibilities that come with it. However, students often get confused on what exactly is required from them during nursing assignment writing. My Assignment Services has a dedicated team of nursing and public health experts who are capable enough to provide the best nursing assignment help in Australia through guided sessions, who have been practically trained as nurses and have a flair for writing university assignments such as dissertations, essays, thesis, case study, research proposal etcetera.
According to our nursing assignment help professionals, the main objective of a nursing course is to prepare holistic nurses who
- Showcase reflection in their practice
- Have completely developed clinical reasoning skills
- Can confidently practice nursing in different environments
Now, that we know the objectives of Nursing course curriculum, let’s take a look at the learning outcomes expected by universities. Our online nursing assignment help experts who provide academic assistance through guided learning sessions, explains the university requirements from a student with the help of a given info-graphic.
Nursing Learning Outcomes
- Meet the requirements for registration as general nurses with the Nursing and Midwifery Board of Australia.
- Deliver nursing care as safe and therapeutic practitioners based on justifiable decisions derived from clinical reasoning and the best available evidence, taking account of the broader contexts of health and health care.
- Critically reflect on their practice.
- Base their nursing practice on a holistic understanding of a person's health status within their social context.
- Practice with an understanding of knowledge from supporting psycho-social and science disciplines.
- Apply the principles and processes Of nursing Inquiry
- Engage in research activities that promote and improve nursing practice and the profession.
- Adapt their nursing practice to the requirements of any situation. individual or Group.
Nursing Assignment Challenges
We have already discussed in brief as to why students face difficulties in writing nursing assignments and scoring high distinction in them. The main challenges faced by students are as below:
- Lack of Time: Time is an important factor when it comes to scoring high distinction in your assignments. Students are always well-read on their subject and the topics. However, the submission time-frame for assignments are quite stringent, therefore, most students are unable to give time to bring out the best in their assignments. That is why there are nursing assignment writing services to help you in every sphere in achieving your dream. Moreover, students receive multiple assignments at once and are not able to give ample attention to any one of them, therefore, compromising on the quality of all their assignments. My Assignment Services has a team of academic writers with decades of experience in providing the highest quality of assignments well within the submission date. If you require online nursing assignment help services through guided sessions and if you want it in a day, you can completely trust us to do a stellar job.
- Incoherent Understanding of University Requirements and Marking Rubric: University Nursing assignments can be of different types. For instance, dissertation, thesis, case study, essays etcetera are all part of nursing but have completely different guidelines from each other. Students are often perplexed with the complexity of these guidelines and are unable to match the university’s expectation. That makes them getting help with nursing assignment experts because it saves their time so that they can go and carry their other activities. Also, another factor that is equally responsible for lower grades in nursing assignment is understanding the Marking Rubric. An assignment can have several questions and several sub-questions. Universities allot marks to these questions in respect to their weightage and importance. Students often fail to grasp the marking rubric comprehensively. This leads to the student spending more time on a relatively insignificant portion of the assignment, rather than completing those with considerable weightage in terms of marks. Our online assignment nursing help experts, at My Assignment Services, are well versed with marking rubric and in comprehending the university guidelines. They have been providing nursing assignment help through guided sessions to students from prominent universities, in Australia and across the globe, for nearly a decade. They understand which section should be given time and effort for research according to the marking rubric. This ensures consistency and gets you good grades.
- Procrastination : University students are burdened with examination preparation, part-time jobs, socio-cultural events, and extra-curricular activities. Nursing assignment are an important part of this routine, however, they are also long, complex and time taking. This is why students tend to procrastinate writing assignments on their own. Next time when you think of “who can do my assignment”, think of My Assignment Services. Our team of native Australian academic writers love to leave aside their day-to-day activities, and will definitely provide you help with nursing assignments in order to write assignments. Their flair for writing compliments their passion for assisting students in achieving high distinction.
Looking for Nursing Assignment Help?
If you are looking for online professional nursing assignment helper through guided sessions, look no further! Students pursuing nursing courses in Sydney, Melbourne, and Perth regularly avail of our nursing assignment help through guided sessions. Although, our nursing assignment experts provide academic writing to students from all over the globe, being native Australian writers gives them an edge over other experts. They understand the laws and regulations of Nursing in Australia and have written their own assignments at one point of time. They are also well-versed with the University requirements and the marking rubric, which makes us the best nursing assignment help service provider through guided sessions. While attempting nursing assignment, not considering the marking rubric is an amateur mistake. Our experts write the assignments according to the marks assigned to each question and sub-questions. This ensures that the assignment is precise, relevant and achieves full marks in all the sections.
Why consider My Assignment Services for your Nursing Assignments?
It is very difficult to stand out from the masses when it comes to providing academic writing services. We know have many competitions in the market. But who will emerge as the best nursing assignment help provider through guided sessions, has set of qualities that stands out against the crowd. Therefore, we understand that every assignment is priceless as it determines and impacts a student’s future career prospects. We also understand how much trust students put on us when they buy online nursing assignment help through guided sessions from us. This is why we approach the assignments head on, utilising our best resources according to the requirements of the assignments. Here is what makes us different;
Ph.D. Holder Assignment Experts
To deliver exceptionally well written high-quality assignments, academic writers with experience, knowledge and flair for writing is preferred everywhere. We set our bar high by involving only the highest qualification holder who is specialised in their respective subjects to provide the students with nursing assignment help through guided sessions. All our experts are either Ph.D. holders, or are pursuing their Ph.D. from prominent universities in Australia. These nursing assignment academic experts have years of theoretical knowledge and practical skills that come with on-job training. They understand every assignment comprehensively and leave no stones unturned while writing your assignment.
Dedicated Quality Analyst Team
Once our subject matter expert has completed your assignment, it passes through our dedicated team of Quality Analysts. Unlike other nursing assignment services online, our quality analysts utilise plagiarism checker tools like Turnitin to ensure that not even one percent of the text is plagiarised. They read the assignments word by word to eliminate the minutest of typographical or grammatical errors. Moreover, they have a quality checklist that is matched against every assignment to see whether the academic expert has followed required university guidelines like indentation, formatting, structure, and punctuations. Once your assignment passes our Quality Analyst team, you can be assured when you go for our plagiarism free nursing assignment help services through guided sessions.
On-time or Before Time Delivery
Online nursing assignment service are often unreliable. Assignments need to be submitted on time, failing which, it attracts penalties in terms of marks deduction. Also, some universities have their web portal for assignment submission. This portal is automated and closes immediately after the submission time has passed. Students are often hesitant in taking online nursing assignment help writing service through guided sessions because they fear that they won’t be able to submit the assignments on time. My Assignment Services, since its inception, has never missed a single deadline. We are proud of our nursing assignment experts, who take every stringent deadline as a challenge and are always able to deliver the assignments without compromising on the quality.
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Students often have tight budgets and are already burdened with student-debts and education loans. We understand this perfectly well, and this is why we provide customized nursing assignments at reasonable prices. If you are looking for an affordable solution for nursing assignment service that does not compromise on the quality and relevancy of your assignments, you can trust My Assignment Services.
Get quality nursing assignment help through guided sessions and achieve high distinction every time when you take assistance from My Assignment Services. We are one of the most prominent and leading services that provide the best nursing assignment help in Australia through guided sessions. | <urn:uuid:d4006d76-8744-4904-a0f9-2b11c3410536> | CC-MAIN-2022-33 | http://www.assignmenthelpera.com/nursing-assignment-help | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.962729 | 3,122 | 1.8125 | 2 |
Keywords : otitis media
CLINICO-MICROBIOLOGY OF CHOLESTEATOMA OBTAINED DURING MASTOID SURGERY IN PATIENTS WITH CHRONIC SUPPURATIVE OTITIS MEDIA
Basrah Journal of Surgery,
2021, Volume 27, Issue 1, Pages 36-40
Abstract Chronic Otitis Media (COM) is a long standing inflammation of the middle ear and mastoid, it is a common health problem. The evidence of microbiology in COM in different studies showed variable frequencies, but little studies showed the role of fungal colonization. This study aimed to identify the microbiology of cholesteatomatous COM concentrating on clarification of fungal colonization. A prospective study was done in otolaryngology department of Basrah Teaching Hospital from June 2018 till July 2019. This study was carried on a randomly collected data of 25 patients diagnosed as COM by a specific designed questionnaire including history and examination. The specimen was collected during mastoid surgery which included any cholesteatoma in the middle ear and mastoid and sent for bacteriological and mycological examination. Statistical study was done by using SPSS v.23 Bacteria were isolated in 84% of the cases in which Pseudomonas aeruginosa was the commonest one (33.3%). Fungi were isolated in 28% cases, in which the Aspergillosis was the commonest (19.3%). There is no recognizable pattern of significant association between the fungi and the reported complications or the stage of the disease. In conclusion, there is significant percentage of fungal colonization in COM with cholesteatoma so it may has a role in inflammatory response of perimatrix, but there is no clear mechanism of this interaction, so may need larger sample and longer duration of study with postoperative follow-up and trail of combined antibiotic-antimycotic treatment. Key words: clinical,microbiology, cholesteatoma, mastoid surgery, otitis media.
Basrah Journal of Surgery,
2019, Volume 25, Issue 2, Pages 70-75
Otitis media with effusion (OME) is a chronic accumulation of fluid within the middle ear cleft and sometimes the mastoid air cells system. The disease is more common among children. Surgical management is cost effective and carry complications from anaesthesia and surgical intervention. The condition can be resolved with high percentage by using mucopeptide breaking agent N-acetylcysteine
The aim of this study is to evaluate the effect of N-acetylcysteine on the resolution of otitis media with effusion in children.
Fifty seven children (107 ears) aged between 4-15 years with OME were included in this study. Patients underwent a thorough otorhinolaryngological examination and were divided into two groups; in the study group of 30 patients, N-acetylcysteine was administered, and the control group of 27 patients did not receive this treatment.
Patient were followed-up at attendance, one month, two months and three months later with microscopical ear examination, tympanometric and pure tone audiometric examination.
Patients were 39 males (68.4%) and 18 females(31.6%), 50 of them were with bilateral and 7 with unilateral disease. Following the treatment, there was improvement in the hearing loss as air bone gap was decreased. This improvement was statically significant in comparing the study and control groups (P value= 0.022). Number of ears with type A tympanogram increased to a rate of 74%, 71% in the right and left ears respectively in the study group. This rate was statically significant in comparing with the control group (P value=0.014).
In conclusion, N-acetylcysteine is effective in the treatment of children with OME as well as that N-acetylcysteine has minimal side effect and can be used safely in patients who are medically unfit for general anaesthesia | <urn:uuid:1a9010da-b8ef-4eaa-9497-1259f8ba0822> | CC-MAIN-2022-33 | https://bjsrg.uobasrah.edu.iq/?_action=article&kw=67620&_kw=otitis+media | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.953726 | 868 | 2.078125 | 2 |
Head office of Town Planning Department is situated at Jaipur and headed by Chief town Planner. It has 6 Zonal offices at Divisional Headquarters except Bhartatpur (Ajmer, Bikaner, Kota, Jaipur, Jodhpur, Udaipur) and 2 Regional offices at Alwar and Bharatpur. Zonal offices are headed by Senior Town Planner and Regional Offices are headed by Deputy Town Planner. In addition to above, 25 Districts have been covered by District Town Planning units. Additionally, department has a unit under Chief Town Planner (NCR) to coordinate and undertake planning and coordinating projects in Rajasthan Sub-Region of NCR.
Organization structure chart is placed annexure ‘A.’
Interface with Urban Local Bodies/Public
The master plans/sector plans prepared by this department are used by Urban Local Bodies to undertake development of the town through schemes/ projects besides giving permission to individuals, developers, builders, etc. for physical development. The department does not have any public dealing directly, however, the master plans prepared by it affects every citizen of the town. Any permission being given by the Local Body, Development Authority or UIT is in the context of these master plans and therefore, every case related to land development considers these documents for approval. The master plans/sector plans etc. give proposed land use due to which everyone wants to know the land use assigned to his khasra nos./land Flow of information like maps/schemes/etc. takes place between Zonal Offices/UIT’s/Development Authorities/Director Local Bodies/RHB in internet for faster clearance. The department also receives change in land use cases of individual applicants through ULBs. In this manner there is a indirect interface with the public. | <urn:uuid:286cf33e-5596-4222-a0bf-6e8d2eb41997> | CC-MAIN-2022-33 | https://urban.rajasthan.gov.in/content/raj/udh/ctp/en/about-us/organisational-structure-.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.95213 | 391 | 1.734375 | 2 |
Weight Bearing is a series of photographic images that utilises self-portraiture and humour to depict internalised emotions felt by the PI when she suffered from an undiagnosed disordered eating as a teenager. The images utilise constructed and self-portrait photographic methods to explore the topic of disordered eating using surrealist visuals. Each image in the series represents a contemporary reflection on a situation that occurred 30 years prior during the disordered eating phase. The 8 situations are recreated to depict the scenes in which they originally take place and employ props that depict the extreme thoughts that exist within the mind of someone who is suffering from disordered eating.
- Eating disorders
- mental health and wellbeing | <urn:uuid:8469006c-0503-4494-adaa-6c589d5acfe6> | CC-MAIN-2022-33 | https://pure.northampton.ac.uk/en/publications/weight-bearing | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573399.40/warc/CC-MAIN-20220818185216-20220818215216-00072.warc.gz | en | 0.960124 | 160 | 1.65625 | 2 |
The US Geological Survey recently released findings that show, as many people have suspected, that the process known as fracking is directly related to the incredible increase of earthquake incidence in the United States.
According to the study, the amount of earthquakes has increased dramatically over the past few years.
Between the years 1973–2008, there was an average of 21 earthquakes of magnitude three and larger in the central and eastern United States.
This rate jumped to an average of 99 M3+ earthquakes per year in 2009–2013, and the rate continues to rise. In 2014, alone, there were 659 M3 and larger earthquakes .
Most of these earthquakes are in the magnitude 3–4 range, large enough to have been felt by many people, yet small enough to rarely cause damage.
There were reports of damage from some of the larger events, including the M5.6 Prague, Oklahoma earthquake and the M5.3 Trinidad, Colorado earthquake.
This increase in earthquakes prompts two important questions:
- Are they natural, or man-made?
- What should be done in the future as we address the causes and consequences of these events to reduce associated risks?
A team of USGS scientists led by Bill Ellsworth analyzed changes in the rate of earthquake occurrence using large USGS databases of earthquakes recorded since 1970. The increase in seismicity has been found to coincide with the injection of wastewater in deep disposal wells in several locations, including Colorado, Texas,Arkansas, Oklahoma and Ohio.
Much of this wastewater is a byproduct of oil and gas production and is routinely disposed of by injection into wells specifically designed and approved for this purpose.
Hydraulic fracturing, commonly known as “fracking,” does not appear to be linked to the increased rate of magnitude 3 and larger earthquakes.
Although wastewater injection has not yet been linked to large earthquakes (M6+), scientists cannot eliminate the possibility. It does appear that wastewater disposal induced the M5.3 Raton Basin, Colorado earthquake in 2011 as well as the M5.6 quake that struck Prague, Oklahoma in 2011, leading to a few injuries and damage to more than a dozen homes.
Current and Future Research
The USGS is coordinating with other federal agencies, including the EPA and Department of Energy, to better understand the occurrence of induced seismicity through both internal research and by funding university-based research with a focus on injection-induced earthquakes from wastewater disposal technologies.
For instance, USGS and its university partners have deployed seismometers at sites of known or possible injection-induced earthquakes in Arkansas, Colorado, Ohio, Oklahoma and Texas.
The USGS is also monitoring seismicity associated with a geologic carbon dioxide sequestration pilot project at Decatur, Illinois, and is working with industry, academia and other government agencies to study seismicity associated with geothermal energy development and production in California and Nevada.
Evidence from some case histories suggests that the magnitude of the largest earthquake tends to increase as the total volume of injected wastewater increases. Injection pressure and rate of injection may also be factors. More research is needed to determine answers to these important questions. | <urn:uuid:6c3db8ac-f86b-44b0-9800-67baa120bed5> | CC-MAIN-2022-33 | https://csglobe.com/government-confirms-increased-earthquake-activity-related-to-fracking/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.968375 | 648 | 3.46875 | 3 |
Increasing good work
Putting people over profit
Global inequality has doubled in the last decade. Precarious work is on the rise, millions work for less than they can live on and we’re still 100 years away from closing the gender pay gap. Investor demand for profit has driven this inequality – they have a role to play in providing the solution.
Covid-19 shone a spotlight on these global challenges - society is waking up to the injustice playing out within workforces around the world. Everyone deserves a fair wage for a fair day’s work. Ending poverty pay and addressing insecure work is no longer just a social and moral imperative. It's good for business too.
Role of the financial system
80 per cent of employers believe a Living Wage has enhanced the quality of work of staff, while 25 per cent saw a reduction in staff turnover.
16 per cent of temporary or part-time workers in the EU and UK were at risk of poverty in 2017 – three times more than standard employees.
Investors and companies relying on insecure work are at increased risk of reputational damage, industrial action and new regulations demanding more disclosure.
25-year-olds on zero-hour contracts are 41 per cent less likely to report good physical health, and one-and-a-half times more likely to report mental health issues. Good quality, secure work coincides with increased productivity, reduced absenteeism and sick leave.
Good Work themes
The shape of work is changing. There has been an increase in insecure contracts – including casual, temporary agency or labour hire, like gig workers and zero-hour contracts. These workers lack rights and protection. We engage with investors to help them push companies to improve workforce practices.
You can’t manage what you don’t measure. Key to driving up workplace standards is clear, comparable data on workforces and company policies and practices. The Workforce Disclosure Initiative (WDI) aims to provide investors with the data needed to drive up standards at the companies they invest in.
Everyone deserves a fair wage for a fair day’s work. This means a wage that meets their basic needs – and those of their families. Yet, today, many workers in the UK and globally work for less than a real Living Wage. We bring together a coalition of investors to urge the FTSE350 to commit to paying a real Living Wage.
Diversity & Inclusion
Businesses do not operate in a vacuum - so structural inequalities and systematic biases in society are reproduced within the workplace. If companies do not take active steps to improve diversity and inclusion, these inequalities will only increase.
Unlocking the power of investors
We benchmark and engage with investors to harness the power of investment for social and environmental progress.Find out more
Reforming the rules
We work with policy makers and regulators to drive the uptake of responsible investment across the UK and globally.Find out more
Building a movement
We educate and empower individuals on how they can use their money to build the future they want.Find out more
Good Work Coalition
It is more vital than ever that we invest in workforces - and there's growing evidence that companies that look after their employees will outperform those that don't. Investors will be key to this, and our investor coalition aims to engage companies to push for better working practices.
Workforce Disclosure Initiative
The Workforce Disclosure Initiative (WDI) aims to improve corporate transparency and accountability on workforce issues, provide companies and investors with comprehensive and comparable data and help increase the provision of good jobs worldwide. | <urn:uuid:e7ac5bf1-e113-4acd-921e-c6b13dff5986> | CC-MAIN-2022-33 | https://shareaction.org/global-issues/good-work?token=rsviN7acauoQpJPcZP2UMRd7x8F9Ufme | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.938534 | 745 | 1.710938 | 2 |
KANAZAWALOW PROFILE HYDRAULIC TORQUE WRENCH (LOW SERIES)
KANAZAWASQUARE DRIVE HYDRAULIC TORQUE WRENCH (IBT SERIES)
Fasten Bolts Easily With a Hydraulic Torque Wrench
Hydraulic torque wrenches are tools used to apply a specific torque level (Nm) to any type of industrial fasteners, such as a nut or bolt. It is often employed when the tightness of such fasteners are crucial to the proper functioning of the equipment or part of the equipment. It is used for various industrial uses in Singapore and overseas.
Industrial Uses of Hydraulic Torque Wrench
A hydraulic torque wrench is used to apply larger torques with far more precision and accuracy. The tool is often used in shipyards as well as in the assembly of heavy machinery, owing to the nature of the equipment and its heavy-duty functions. This type of wrench is typically employed when a lot of pressure is required to apply a torque to the fastener.
There are two types of hydraulic torque wrenches – low profile and square drive – that are used accordingly based on the size of the application area. Our hydraulic torque wrenches are sourced from Kanazawa and suitable for bolts of various sizes under different working conditions.
Due to the high pressure generated through hydraulic means, safe use of the hydraulic torque wrench is essential. Apart from using the safety gear, users are advised to perform safety checks on the wrench before use. Ensure that the pressure gauge is in good working condition as it is crucial to measure the amount of pressure applied when the hydraulic torque wrench is used to carry out the task. Too much pressure beyond the operating limit can cause leakage of hydraulic fluid and cause potential chemical hazards. | <urn:uuid:605367d6-256f-46c0-9923-5a5a4faa03bd> | CC-MAIN-2022-33 | https://allinton.com.sg/product-category/hydraulic-torque-wrench/?filter_brands=kanazawa | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.927154 | 383 | 1.726563 | 2 |
You’re buying a car, you’re lending a friend some money, you’re negotiating a contract with a supplier – they’re promising lots of great things but are you being naïve?
Anyone who has read my work or been on one of my courses will know I’m a firm believer of the win-win approach to negotiation. But, of course, it has an in-built flaw – what do you do if you are dealing with someone who you can’t trust?
You’d never play win-win with a crocodile, would you? Well, you might but don’t expect them to return any favours, its just not on their agenda.
So trust is a critical part of the equation.
And in recent times, trust has become a major area of scientific interest. Whether we are talking about game theory, anthropology, psychology, economics or biology, lots of cross-field work has been done to explore the nature of this invisible force that holds our society together.
A great book called “The Moral Molecule” by Professor Paul Zak, one of the founders of the field of neuro-economics, looks at the chemical oxytocin, sometimes known as “the bonding chemical” and perhaps best known as the factor that makes the mother bond with her new-born baby. Oxytocin, it turns out, is the biological substrate for trust.
What can we learn from lobsters?
Lobsters, we know, have a very hard and knobbly shell to protect them. There is one problem: it stops them having sex. It’s a bit like humans trying to have sex whilst wearing a deep-sea diving suit. It’s not easy. Apparently.
Now, if you’ve seen my video on lobsters you’ll know that, to get around this, the female sheds her shell when she is ready to reproduce. However, this has its own problem – now she is vulnerable and is no longer protected. And we all know unprotected sex can have all kinds of consequences. For female lobsters, unprotected sex might, at worst, mean being eaten by her lover. Doesn’t usually happen with humans; does, though, with lobsters.
So how does the safe-sex-minded lobster get around this? Well, she uses chemical weapons: she sprays a pheromone into the male lobsters cave which makes him less aggressive. She can now get out of her shell and do the do, safe in the knowledge he won’t attack her before she grows another shell.
Wouldn’t it be great if humans had a chemical that made other people become less aggressive so we could trust them more in important situations? Well, we do. The chemical female lobsters use is the lobster version of oxytocin.
And what can we learn from prairie voles?
Prairie voles are small American rodents, they are monogamous and the males are very caring for their partner. Meadow voles are very close cousins but one of the few differences is that the males are far less loyal and tend to sleep around like, erm, rabbits.
It turns out that meadow voles have far less oxytocin receptors in their make-up than do prairie voles which explains the difference in behaviour. How do we know it is down to this? Well, inject meadow voles with oxytocin and the caddish studs suddenly become all caring and cuddly, sticking with their partner even when all sorts of tasty, up-for-it female meadow voles are paraded in front of them.
Girls, you’re interested now, aren’t you?!
But can it help you in your negotiation?
And from crustaceans to rodents to humans, it so happens that what works with lobsters and voles, works with humans too, bonding mother to baby and lover to lover.
But can it help you in your negotiation? Yes, it can. Using classic economists’ tools such as the Prisoners’ Dilemma, the Trust Game and the Ultimatum Game, it has been shown that higher oxytocin levels will make the individual more co-operative and more generous.
Let’s take the Trust Game. In this, Person A is given $10 and is told they can give some of that to Person B. Anything they give will gets tripled in value and Person B can then decide to keep it all or give some back. Person A has to trust Person B’s generosity.
Zak’s experiments showed a direct correlation between their levels of oxytocin and both their trust and their generosity. That is, Persons A gave more money when sprayed with oxytocin and Persons B, when sprayed, returned more too. Importantly, it doesn’t turn people into gullible fools: Persons A would not give more if they were told Person B was untrustable or a computer-based random number generator.
With the Ultimatum Game, a similar construct to the Trust Game, Zak showed generosity increased by 80% under the influence of oxytocin.
Beyond negotiation it has some impressive effects too, by the way. It makes us happier and live longer. Higher levels of the chemical stimulate serotonin and dopamine production, which are the feelgood chemicals. And when Zak performed blood-tests on centenarians, he found significantly higher background levels than normal. He also claims it is the basis of economic wealth. His earlier work as an economist identified trust as one of the key critieria for a prosperous community (trust allows trade which leads to prosperity) and trust has oxytocin as its chemical basis.
It makes you richer, happier and healthier? Hmm, where can I buy this thing?!
What inhibits oxytocin?
So if it’s such a great thing, what causes its levels to go up or down and is there anything we can do to increase it in our negotiating counterparty?
Firstly, some things have a negative impact. Stress and competitiveness have both been shown to reduce oxytocin levels since they increase testosterone levels. Testosterone is an oxytocin inhibitor, so anything which boosts this will impair trust.
As does studying economics! Robert Frank, Professor of Economics at Cornell, conducted studies on students of economic faculties across the United States. He found 1st years were overwhelmingly trusting, 4th years not very at all. He repeated the experiments on students of other courses and was unable to find a similar effect. (Zak and Frank suggests this is because the concept of self-interest is so core to the subject as currently taught). Lesson: don’t trust an economics graduate!
How can we make people more trustable?
But if you want to increase levels of oxytocin in someone else, it turns out that one of the simplest ways is to act trustingly towards them. When a Person B was shown trust they returned 50% more than when simply given money randomly by a computer. What’s more it was a linear correlation. The more money given (ie, the more they were trusted), the higher the oxytocin surge in the recipient.
Touch also works. As does anything that engenders connection or empathy. Rapportful chat, a moving story, friendly games, gossip, dance, having friendly people around, having pets around – they have all been shown in different studies to raise oxytocin levels. As has identification with an in-group. They may not all be possible in your deal but the more of this kind of thing, the better.
You can even do it through diet: chocolate, red wine, fatty foods, capsicums, comfort foods all have an effect. Or language: Nobel laureate Vernon Smith showed that if you used the word “partner” rather than “opponent”, trust levels doubled. In fact, anything that increases the ‘us-ness’ of it, emphasising collaboration and shared goals, has a big impact on oxytocin levels.
Now, breast-feeding and orgasms are two of the most powerful mechanisms found but I am guessing that they’re probably not appropriate in your negotiations.
Be the example
So, let’s go back to our opening question: Can you trust people? The answer is: It depends! Whoa, see the swerve!
But there is good news, you can increase someone’s trustworthiness and there are known mechanisms for doing so. And it’s actually very simple – be the example of the behaviour you want to see. If you want them to be comfortable with you, be comfortable with them; if you want them to be trustable, be trustable; if you want them to be rapportful, be rapportful.
There is bad news, too, though. It puts the onus back on us! Ouch! | <urn:uuid:252bb6a6-eb7f-40ae-b4cd-c67d92dcafe7> | CC-MAIN-2022-33 | https://www.negotiation-mastery.com/the-science-of-trust/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.965239 | 1,864 | 2.125 | 2 |
The question of whether a company needs to keep a company register, or as it is also know, at set of statutory books and records is frequently asked by those setting up a company.
The law requires that every company maintain a set of statutory books and a company register is by far the commonest means of meeting this obligation. They are relatively simple to complete and store and most company registers are capable of housing the statutory transactions of for numerous years.
From a practical point of view, the requirement to maintain a set of company registers and statutory books is in most cases obsolete. The idea behind the legal obligations is that the public have a right to be able to inspect a company’s documents on demand. For the registration of the company, you should have the information about the ventajas fiscales andorra for successful business. The fulfillment of the obligations is necessary to increase the money in the bank account. The demand of the business is rising among the customers for online business.
In reality, only in exceptional circumstances would a request for an inspection of a company registers be made. Those usually occur when a commercially trading company is in the process of being purchased and as part of an Accountant’s due diligence work, the statutory books are audited.
Most other compulsions to view information about a UK company are usually satisfied by downloading statutory filing documents from Companies House for a nominal charge.
This is frequently more convenient than arranging an appointment at a company’ registered office or sail address and then not have the facility to take copies for future analysis.
Given that random requests to view a company’s register are rarely initiated, it could be concluded that it is unnecessary to obtain and keep a company statutory register. Whilst it might be tempting to follow this path it would plainly contravene the current laws as they stand and therefore would be ill-advised.
Company registers are relatively inexpensive and need not present a cumbersome task for the company secretary to maintain. If course it is always the preferred option to comply with the law and avoid any resultant fees levied thought non-compliance. | <urn:uuid:66f499bb-9aae-4984-a51d-06d07c5a0a5f> | CC-MAIN-2022-33 | https://getcambox.com/do-i-need-a-company-register-check-the-requirement/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.951834 | 426 | 1.609375 | 2 |
An old ritual of pre-Roman origin, and with its roots firmly set in an ancient fertility festival dedicated to the goddess Ceres, the Festa dos Tabuleiros is one of the most colourful and traditional events in Portugal’s cultural calendar.
This very rare spectacle takes place once every four years in Tomar, a historic town conveniently located deep in the heart of central Portugal. The Order of the Templars was founded here in 1119 and its star attraction, the Convent of Christ, was built over a period of six hundred years.
Other must-see sights in Tomar include the late-15th century Gothic church of São João Baptista on the town’s main square (don’t miss the magnificent Last Supper painted by Gregório Lopes in the early 16th century) and a small Jewish museum housed in a 15th-century synagogue.
The Tabuleiros Festival was co-opted in the 14th century by the Brotherhood of the Holy Spirit – the latter founded by Queen Isabel as a means of gathering donations for the poor (Queen Isabel was later canonised as Saint Elizabeth of Portugal).
The event’s key moment is without doubt the Tabuleiros Parade in which young women dressed in pure white parade around the streets carrying on their heads tabuleiros (platters) of bread that are often as tall as they are. Their headdresses are bread loaves fixed by a bamboo frame decorated in red, yellow and purple paper flowers.
These tabuleiros consist of some thirty loaves of bread in all threaded onto rods attached to wicker baskets decorated with paper flowers, leaves and stalks of wheat, occasionally topped by a dove. The bounty was symbolically offered to the Holy Spirit as represented by the dove, the symbol of universal fraternity espoused by the Brotherhood.
Behind the girls and their escorts, priests carry silver crowns on black cushions followed by a marching band and a herd of bullocks with gilded horns and coloured wreaths. The parade also features horse and chariot cavalcades proudly parading along Tomar’s streets gaily paved with flower tapestries on religious and medieval motifs.
The Festa dos Tabuleiros, which literally translates as the Feast of the Trays, is one of southern Europe’s most lavish harvest festivals and a true cultural showpiece deep in the heart of Portugal’s hinterland.
The next one is due to take place in July 2023 (global pandemics permitting), but if you’re planning to visit you must book early because rooms are very scarce throughout the entire duration of the festival.
And once the Tabuleiros festivities are over, you’ll want to explore the region and discover some of the other principal towns and villages, such as the pretty whitewashed town of Constância 20 km south-east of Tomar which marks the point where the Tagus and Zêzere rivers meet.
Also worth seeing is the Castle of Almourel situated on an island in the Tagus, a short drive east of Constância. This fairy-tale fortress of Disney-like proportions was built on the foundations of a primitive Lusitanian castro and is one of Portugal’s most strikingly scenic fortresses.
Need more inspiration for your next visit? Why not listen to or download the Portugal Travel Show, the podcast for people planning a trip to sunny Portugal… | <urn:uuid:dc4d8ad3-9020-47fa-9d7f-bca359ca08c7> | CC-MAIN-2022-33 | https://portugaltravelguide.com/festa-dos-tabuleiros/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.952979 | 721 | 2.359375 | 2 |
Are you looking to buy a home? Do you know how much you can afford to pay each month for a mortgage payment? Did you know that your mortgage payment includes more than just the amount you’re financing for your mortgage loan?
There are actually 4 elements that make up your monthly mortgage payment. These elements are called PITI.
- Principal – the amount of your payment that goes toward repaying the principal of your loan, in other words, the dollar amount you borrowed for your loan.
- Interest – the amount of your payment that goes toward repaying the interest on your loan. The interest is the amount you are charged for borrowing the money to buy your home. Interest rates can change daily based on how well the economy is doing.
- Taxes – the amount of your payment that goes into your escrow account to pay your property taxes. When you’re buying a home, the seller may list the amount of taxes owed annually on the property. Or, you can get this information from the local property tax assessor’s office. To determine what you will owe monthly for your taxes, divide the annual amount by 12. This monthly amount is what will be added to your monthly mortgage payment to cover your tax payment. When your taxes are due, your lender will pay them for you from the funds they have collected in your escrow account. However, it’s important you understand that your property taxes can go up (or down) over the years.
- Insurance – the amount of your payment that goes toward paying your homeowner’s insurance. It’s important that you carry property insurance on your home to protect yourself in case of loss. It’s best that you insure your home based on its replacement value – the cost to rebuild your exact home. Several factors go into determining the cost of your premiums, such as the age of the home, the size, the materials used in construction (i.e., brick, wood, concrete) and where it is located. Once you receive the annual amount for your homeowner’s insurance from your insurance agent, divide the amount by 12 to determine how much this will increase your monthly mortgage payment. Like your taxes, your insurance premiums can change over time, too – usually by going up.
Another factor beyond PITI which may play a role into determining if you can afford a certain home is the homeowners’ association dues. These are annual or monthly fees that the housing community requires you to pay to cover shared community costs, such as lawn care, street lighting, or maintenance on community amenities like a swimming pool, clubhouse or playground.
Obviously, it’s important to consider all four elements – Principal, Interest, Taxes and Insurance (and homeowners’ association dues) – when determining how much you can afford for a home.
If you looking to buy a new home, Grandview Lending can help you find the right mortgage loan for your needs. Contact us today! | <urn:uuid:228c92c5-c520-42e4-8df6-3ff4eed5d475> | CC-MAIN-2022-33 | https://grandviewlending.com/understanding-your-mortgage-payment-piti/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.961852 | 607 | 2.59375 | 3 |
The main town in the area, it has a rich history steeped in shipbuilding and seafaring. Greenock grew from a fishing community to become the site of the first dock on the Clyde in 1711 and is most famous for ships, steam, sugar and being the birth place of James Watt.
Today it is a large town offering a range of facilities for visitors to the area. It is the largest cruise port in the country welcoming over 85,000 passengers a year.
There is a lot of discover and explore, find out what’s on and where to go through the pages on this website. | <urn:uuid:31c71ef1-b9e6-4c79-9f37-f49ef2474cd7> | CC-MAIN-2022-33 | http://discoverinverclyde.com/location/greenock/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.963417 | 125 | 1.835938 | 2 |
The Australian senate this week passed new laws that will require businesses and government agencies to notify the Privacy Commissioner and customers if they have experienced a data breach. A copy of the Bill can be found at the following link: http://www.austlii.edu.au/au/legis/cth/bill/padbb2016356/
A data breach arises where there has been unauthorised access to, or unauthorised disclosure of, personal information about one or more individuals, or where such information is lost in circumstances that are likely to give rise to unauthorised access or unauthorised disclosure.
As to the level of harm that would bring a data breach within the scope of the new legislation: A data breach is an eligible data breach where a reasonable person would conclude that there is a likely risk of serious harm to any of the affected individuals as a result of the unauthorised access or unauthorised disclosure.
The level at which the notification regime would be triggered was the subject of much debate in Australia. As the Explanatory Memorandum for the legislation stated ( see: http://parlinfo.aph.gov.au/parlInfo/download/legislation/ems/r5747_ems_ed12b5bb-d3b3-4a6a-9536-53bb459a00df/upload_pdf/6000003.pdf;fileType=application%2Fpdf )
“It would not be appropriate for minor breaches to be notified, because of the administrative burden that may place on entities, the risk of ‘notification fatigue’ on the part of individuals, and the lack of utility where notification does not facilitate harm mitigation.”
The Memorandum goes on to explore “serious harm”:
“Serious harm, in this context, could include serious physical, psychological, emotional, economic and financial harm, as well as serious harm to reputation and other forms of serious harm that a reasonable person in the entity’s position would identify as a possible outcome of the data breach. Though individuals may be distressed or otherwise upset at an unauthorised access to or unauthorised disclosure or loss of their personal information, this would not itself be sufficient to require notification unless a reasonable person in the entity’s position would consider that the likely consequences for those individuals would constitute a form of serious harm.”
If an organisation has taken remedial action after a breach that results in a situation where it’s unlikely the incident will result in serious harm to affected individuals, it won’t be required to report the incident.
- Organisations may need to get legal advice to assist in making judgments as to a “likely risk of serious harm” under the new provisions in circumstances where they have been subject to a data breach.
Under the new laws organisations must notify the Privacy Commissioner and affected customers “as soon as practicable” after becoming aware that a data breach has occurred.
- Organisations should seek advice on the content and communication strategy for notifications to the Privacy Commissioner and affected customers.
The new laws will commence on a date to be fixed over the next twelve months.
Small business exception
Australian privacy legislation has a small business exception – that practically exempts many Australian businesses from the need to comply with these laws. The laws cover most Australian Government agencies and all private sector and not-for-profit organisations with an annual turnover of more than AU$3 million.
Consequences of breach of the new legislation:
Initially the Privacy Commissioner can issue a written direction requiring an organisation to notify of the breach if they discover it has occurred.
The Commissioner may otherwise investigate any interference with the privacy of an individual, whether as a result of a complaint or on his own initiative. After investigating, the Commissioner may make a determination requiring the organisation to take certain steps. The Commissioner may commence court proceedings to enforce the determination.
The Privacy Commissioner may apply to the Federal Court or Federal Circuit Court for a civil penalty order against an organisation of up to $1.8 million where it finds a serious or repeated interference with privacy. | <urn:uuid:9c86e9d1-6251-4bde-814c-0b904980198f> | CC-MAIN-2022-33 | https://www.lexology.com/library/detail.aspx?g=39a3e741-dacb-4f01-a200-9a5cad56d0c6 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573399.40/warc/CC-MAIN-20220818185216-20220818215216-00072.warc.gz | en | 0.923993 | 852 | 2.15625 | 2 |
“I must have flowers,
— Claude Monet
“Happiness radiates like the fragrance from a flower and draws all good things towards you.” — Maharishi Mahesh Yogi
As if Annecy’s Vieille Ville, or old town, isn’t charming enough with its “Venice of France” river and canals meandering between historic buildings and a crisscross of bridges, the town and its residents add beauty on top of beauty with artwork and flowers wherever they can. We found the city decorated with floral sculptures and carvings, such as this eye-catching pink beauty with petals that moved slowly upward as if an opening blossom on the town’s center plaza.
The Palais de l’ile, situated on an islet right in the middle of the Thiou River canal, was decorated with its own plant sculpture. Once a residence of the Lords of Annecy, the 17th century palace later became a prison and then, among other functions, a home for veterans. It serves today as a museum, showcasing Annecy heritage and architecture exhibitions.
“The magic of the street is the mingling of the errand and the epiphany.”
― Rebecca Solnit
“People from a planet without flowers would think we must be mad with joy the whole time to have such things about us.” — Iris Murdoch
“If you know the art of finding some things in a quite empty street, then you know the art of happiness!” — Mehmet Murat ildan
“In a simple street you can find the whole world: You can find joy and sorrow; you can find good and evil, silence and noise; you can find all the comedies and all the tragedies! An ordinary simple street is the mirror of the whole world!” ― Mehmet Murat ildan
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Next post, a cruise around the picturesque Lac d’Annecy before departure for home.
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- Meeting report
- Open Access
Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report
Malaria Journal volume 15, Article number: 476 (2016)
Placental malaria caused by Plasmodium falciparum infection constitutes a major health problem manifesting as severe disease and anaemia in the mother, impaired fetal development, low birth weight or spontaneous abortion. Prevention of placental malaria currently relies on two key strategies that are losing efficacy due to spread of resistance: long-lasting insecticide-treated nets and intermittent preventive treatment during pregnancy. A placental malaria vaccine would be an attractive, cost-effective complement to the existing control tools. Two placental malaria vaccine candidates are currently in Phase Ia/b clinical trials. During two workshops hosted by the European Vaccine Initiative, one in Paris in April 2014 and the other in Brussels in November 2014, the main actors in placental malaria vaccine research discussed the harmonization of clinical development plans and of the immunoassays with a goal to define standards that will allow comparative assessment of different placental malaria vaccine candidates. The recommendations of these workshops should guide researchers and clinicians in the further development of placental malaria vaccines.
People living in malaria endemic areas gradually develop immunity to clinical manifestations of Plasmodium falciparum infection, and severe malaria is unlikely above 5 years of age in areas of stable transmission . However, during their first pregnancy, women become susceptible to placental malaria regardless of previous exposure to the parasite. Over 50 million women living in endemic areas are exposed every year to the risk of developing malaria during pregnancy. Placental malaria can have serious consequences for both mother and child [2, 3] and is estimated to cause between 75,000 and 200,000 infant deaths every year .
The currently recommended preventive strategies to reduce the risk of placental malaria are based on the use of insecticide-treated bed nets and the intermittent administration of anti-malarial drugs. Unfortunately, these approaches are now reaching their limits, becoming progressively less effective due to the emergence of drug and insecticide resistance in the parasite and its vector, respectively. Women in endemic areas urgently need novel interventional methods. In areas of stable transmission, the prevalence and severity of placental malaria diminish with successive pregnancies [5, 6] demonstrating that immunity is acquired as a result of natural infection, and supporting the prospects for a vaccine that protects pregnant women and their children from the dire consequences of placental malaria [7, 8].
Infected erythrocytes isolated from placentas of women (iRBCPM) present a unique adhesive phenotype. iRBCPM do not bind to the common receptors used by the parasite to adhere to the microvascular endothelium [9, 10], but rather bind to the glycosaminoglycan chondroitin sulphate A (CSA). Chondroitin sulphate proteoglycans are present in the placental intervillous space by the end of the third month of gestation , when uteroplacental circulation is fully established, thus offering a potential anchor point for iRBCPM. VAR2CSA, which is expressed on the surface of iRBCPM, has been identified as the parasite-derived protein mediating the adhesion to placental CSA [12–15]. VAR2CSA is a high molecular weight protein, with a 300 kDa extracellular region organized in 6 Duffy-binding like (DBL) domains and cysteine-rich interdomain (ID) regions (CIDR). Recent studies have shown that a single CSA-binding site is formed by a higher-order domain organization involving multiple VAR2CSA domains [16, 17] and that the N-terminal region plays a major role in CSA adhesion [18, 19], with the minimal binding domain located in ID1-DBL2-ID2 .
The European Vaccine Initiative (EVI) and its partners have been instrumental in mobilizing funds for the development of a vaccine against placental malaria, through the PRIMALVAC (Institut National de la Santé et de la Recherche Médicale, Inserm, France) and PAMCPH (University of Copenhagen, UCPH, Denmark) projects funded by the German Federal Ministry of Education and Research through Kreditanstalt für Wiederaufbau, the Irish Aid and the Danish National Advanced Technology Foundation as well as the PlacMalVac (University of Copenhagen, Denmark) project funded under European Commission Seventh Framework Programme (FP7). Both, the PRIMALVAC and PAMCPH/PlacMalVac projects currently have VAR2CSA-based vaccine candidates in Phase Ia/b clinical trials.
Although the two vaccine candidates are based on the same protein VAR2CSA, the selected antigens encompass different VAR2CSA regions and sequences with potentially distinct antigenic properties that might complement each other in terms of immunogenic potency and protective efficacy. While the PRIMALVAC project has selected DBL1X–DBL2X, a 105-kDa domain of VAR2CSA from the P. falciparum strain 3D7 expressed as a recombinant protein in Escherichia coli (PRIMVAC), the PAMCPH/PlacMalVac projects focus on ID1-DBL2X-ID2a, a 73-kDa derivative of VAR2CSA from the P. falciparum strain FCR3, produced as a recombinant protein in Drosophila melanogaster Schneider-2 (S2) cells (PAMVAC). Both candidates entered clinical testing in May 2016. Each vaccine candidate will be assessed in a staggered Phase Ia/b clinical trial where the Phase Ia stage will start in malaria naïve populations in Europe, followed by Phase Ib stage targeting malaria endemic populations in Africa.
Aims of the workshops
In order to facilitate the harmonization of the clinical development of placental malaria vaccine candidates, EVI organized joint workshops on the 24th of April 2014 at the Institut Pasteur, Paris, France and on the 19th of November 2014 in Brussels, Belgium.
The aim of the first workshop was to bring together the researchers involved in the PRIMALVAC, PAMCPH and PlacMalVac projects, including those implicated in the clinical trials in Europe and in Africa, as well as a panel of worldwide experts to establish the preferred product characteristics for a placental malaria vaccine, and to refine the clinical development plan and the design of the Phase I clinical trials. The second workshop aimed at initiating collaboration between the PRIMALVAC and PAMCPH/PlacMalVac teams to develop harmonized functional immunoassays that would allow comparison of preliminary immunogenicity analyses of the two placental malaria vaccine candidates under development. The outcomes of the workshops are summarized in this report.
Design of the Phase Ia/b clinical trials
Preferred product characteristics
In order to drive the vaccine development strategy, preferred product characteristics need to be defined, including target population, indications, route of administration, vaccination schedules, and the clinical data required to assess the safety and perform a preliminary efficacy analysis. The panel agreed that VAR2CSA-based vaccine candidates will be indicated to prevent the complications of placental P. falciparum malaria in pregnant women, aiming to protect both the mother and the fetus. In early clinical development, the vaccine candidates should be administered to women from P. falciparum malaria endemic areas prior to their first pregnancy.
Owing to its simplicity and the expectation that malaria exposure during pregnancy will naturally boost protective responses, workshop attendees agreed that a single intramuscular immunization will be an ultimate goal, but at this early stage of development the need to assess the immune response profile supports a three dose regimen, potentially with a booster to ensure longevity of the protective immune response elicited by the vaccine. Because malaria prevalence has decreased in many communities, the impact of boosting by natural infection should be factored into vaccination schedules and efficacy analyses. Furthermore, the age at the time of vaccination will be influenced by possible coordination or combination with other vaccines, e.g. vaccines against human papilloma virus (HPV), tetanus, rubella or booster of a future marketed paediatric malaria vaccine in young girls. The clinical development plan should document the absence of immunological or clinical interference with any co-administered vaccines.
The clinical development of placental malaria vaccines should follow the clinical section of the World Health Organization’s “Guidelines on the quality, safety and efficacy of recombinant malaria vaccines targeting the pre-erythrocytic and blood stages of P. falciparum” . However, those guidelines are general and do not take into consideration the effects on the fetus and neonate, which should be included in the endpoints for evaluating the placental malaria vaccine candidates.
The endpoints and the case definition should include all episodes of malaria that meet the case definition, (1) clinical malaria is the presence of fever, defined as an axillary temperature of ≥37.5 °C, and (2) parasitological diagnosis based on a parasite density threshold quantified by microscopy with defined and accurate specificity and sensitivity. Severe malaria, co-morbidities, and efficacy against infection are further defined in the guidelines, and should also be considered. Given that the most common presentation during pregnancy is of infection without overt clinical symptoms, it is likely that efficacy against placental infection and children birth weight will be prioritized endpoints.
Target groups and administration
The vaccine is indicated for the prevention of the complications of P. falciparum placental malaria in pregnant women, and will offer protection to the mother and fetus.
The intended population is nulligravid females in areas with endemic P. falciparum malaria. Pregnant women are specifically excluded. Therefore, the vaccine will protect pregnant women, but will be administered before first pregnancy.
The dose regimen
The vaccine will be administered in three intramuscular doses.
The potential for co-administration
The vaccine will ideally be co-administered as a package for young girls with vaccines against HPV, tetanus and/or rubella, also potentially future marketed paediatric malaria vaccine.
Safety and efficacy
The safety and reactogenicity should be comparable to recommended vaccines in immunization programmes in the endemic countries. There is not yet an accepted protection rate for a placental malaria vaccine, but the goal is that the placental malaria vaccine will reduce the incidence of placental malaria outcomes such as low birthweight to a similar degree as naturally acquired immunity in multigravidae. The duration of protection is very important as the time to pregnancy after vaccination could be several years; the period during which naturally occurring boosting occurs should be an endpoint for evaluation.
Clinical development plan
The aim of this workshop was to establish at least an outline of a clinical development plan. The clinical development plans for both projects were considered in three stages, namely Phase I clinical trials assessing the safety and immunogenicity in healthy adult populations. After meeting critical safety and immunogenicity endpoints discussed above, a series of Phase II clinical trials will enroll an exclusively nulligravid adolescent/adult endemic population and assess additional immunological endpoints and preliminary efficacy markers. These clinical trials will involve a significantly larger population. If the vaccine candidate shows promising safety, immunogenicity and efficacy results then it can be moved to Phase III clinical trials involving a larger nulligravid endemic target population.
The panel agreed that the fast track strategy designed by EVI and its partners could be applied to Phase I clinical trials and even later Phase clinical trials to accelerate clinical development. This fast track strategy allows for Phase I clinical trials to be reduced to one single staggered Phase Ia/Ib clinical trial where the Phase Ia stage of the clinical trial starts in healthy adult males and females from a malaria non-endemic population, and the Phase Ib stage is restricted to the targeted healthy nulligravid endemic population. As Phase IIa challenge studies are not feasible for the evaluation of the efficacy of placental malaria vaccine candidates, the fast track strategy will allow a fast transition to the target population. The age range of the nulligravid subjects in an endemic region will span from the national age of majority in the country hosting the clinical trial to the upper age limit of 35 years, with the expectation that few nulligravid women will be older than this in the target population.
The Phase II clinical trials will include assessment of dosage, formulation, age group de-escalation, and interaction with other vaccines. Depending on the results, additional Phase I or even pre-clinical studies may be required.
In terms of the safety requirements for transition from the Phase I stage in non-endemic region (Phase Ia) to the Phase I stage in endemic region (Phase Ib) of the first clinical trial, there should be no serious adverse events definitely related to the vaccine candidate, and serious adverse events possibly related to the vaccine candidate or grade 3 adverse events lasting for more than 48 h should be reviewed by the independent safety monitoring board appointed for the clinical trial with recommendation made to the sponsor. The phase Ib data will be evaluated for both safety and immunogenicity, and the threshold criterion for further clinical development requires at least 60 % seroconversion against the vaccine candidate antigen in the target population. The major outcomes on the clinical development plan are depicted in Table 1.
Design of the Phase Ia/b clinical trials
Based on the recognized need to have harmonized clinical trials that would allow comparison of the Inserm and UCPH vaccine candidates, the rationale for the design of the Phase Ia/b clinical trials was discussed.
The panel agreed the clinical trials will be randomized and double blinded if possible, with due consideration of the technical and logistic constraints at the trial sites. The vaccine antigen dosage was discussed. It was anticipated from previous malaria clinical trials results with recombinant antigens in adult populations that the appropriate dosage will be around 50 µg per dose. The vaccine antigen will be mixed with the selected adjuvant. The adjuvants will include aluminium hydroxide as reference adjuvant as it is widely used in approved vaccines and easily available. The other adjuvant will be a novel adjuvant that is expected to provide better immunogenicity. The Phase Ia clinical trial stage in Europe will comprise two dosage groups, one given 20 µg of the vaccine antigen (n = 2–3) and the other given 50 µg (n = 6–10), in both cases with aluminium hydroxide and/or a novel adjuvant. The Phase Ib stage of the clinical trial will proceed if safety thresholds in the European arms are met and will also comprise two dosage groups, one at 50 µg and one at 100 µg (each n = 6–10) in both cases with aluminium hydroxide and/or the novel adjuvant. The Phase Ib clinical trial stage in Africa will also include a saline placebo group. Saline placebo was chosen instead of HPV vaccine as the dosage schedule selected (0, 1 and 2 months) is not appropriate for the HPV vaccine. However, HPV vaccine offered to all subjects enrolled in the Phase Ib after completion of the clinical trial would be an appropriate benefit to participants.
Potential inclusion/non-inclusion criteria were defined. The main inclusion criteria for Phase Ia stage in Europe will be healthy adult females willing to practice contraception and adult males. The main inclusion criteria in Africa will be healthy nulligravid female adults living in malaria endemic areas willing to practice contraception for the duration of the vaccinations and a defined follow-up period. The main non-inclusion criteria include pregnancy, concurrent infection with malaria, known HIV-positive status and known carriers of Hepatitis B (HBV) or Hepatitis C (HCV). The subjects will be followed for six months after the last dose to assess vaccine safety as per regulatory guidelines and to gather the appropriate immunological and (if possible based on assay development standards) functional data on the performance of the vaccine candidate. As pregnancy outcome in malaria endemic areas could be informative on preliminary efficacy of the vaccine, the protocol and the subject informed consent form should mention that pregnancy outcome information occurring after trial completion could be disclosed to the vaccine trial unit, contingent on the subject’s agreement. The primary endpoint of the Phase Ia/Ib clinical trial was confirmed as safety and a minimal 60 % seroconversion to meet the go criterion for further clinical development (i.e. to proceed with Phase II b clinical trial). The major outcomes on the design of the Phase Ia/Ib trials are depicted in Table 2.
The parallel conduct of two clinical trials with two different VAR2CSA-based vaccine candidates represents a unique opportunity to better understand the immunological processes by which protection against placental malaria can be achieved, particularly humoral immune responses that play the central role during the erythrocytic stage of the infection. The harmonization of the relevant immunoassays across the concurrent placental malaria vaccine projects is thus fundamental to predict and compare the efficacy of the different vaccines and to define go/no go criteria for the design and development of Phase II clinical trials.
In high P. falciparum transmission settings, women gradually acquire immunity to placental malaria following successive pregnancies and primigravid women are at higher risk of developing placental malaria with more severe adverse consequences than multigravid women. This progressive protection has been associated with the acquisition of antibodies able to recognize the surface of iRBCPM [10, 23, 24] and more specifically the parasite-derived protein VAR2CSA [13, 25]. Furthermore, antibodies blocking the adhesion of placenta-derived P. falciparum infected erythrocytes to CSA have been shown to reduce the prevalence of placental malaria and have also been linked to improved pregnancy outcomes . Of major importance, antibodies from multigravid women are able to block the interactions between CSA and iRBCPM originating from different parts of the world, demonstrating the existence of a strain-transcending effective immune response to placental malaria and suggesting a relative conservation of the parasite-derived CSA ligand(s) .
While safety is the primary objective for both Phase Ia/Ib clinical trials, each team has also defined clinical trial secondary and exploratory objectives to evaluate both the immunogenicity of the respective vaccines and the functionality of antibody responses. The analysis of the humoral immune response, the amplitude (the level of vaccine-induced antibodies), is a secondary objective common to both teams. The common exploratory objectives are the assessment of the quality of the immune response, measured as functional inhibition activity of the antibodies, and the assessment of cytokine production by immune cells after ex vivo stimulation with the respective vaccine antigens.
The implementation of common standard operating procedures, reagents, reference standards, equipment and exchange of material/expertise by the UCPH and Inserm teams will be coordinated and supported by EVI. This is advantageous to both teams and to the entire placental malaria vaccine community, as it will establish benchmarks for the immunoassays and contribute to the reliability of the data. One key issue was the selection of assays to be used to quantify immunogenicity, to evaluate preliminary efficacy, and to produce the most reliable data for go/no-go decision-making during later stages of the clinical development.
In order to standardize the immunoassays used in the clinical trials, both teams agreed on using reference standards consisting of pools of sera/plasma isolated from (1) multigravid women living in malaria endemic areas and highly reactive towards VAR2CSA variants (positive pool) and (2) women never exposed to Plasmodium, thus presenting no or very low reactivity against VAR2CSA (negative pool). Questions were raised regarding the size and conditioning of the different pools, their maximal storage duration and the number of clinical trials for which they could be used as reference standards. Based on the panel consensus, Inserm and UCPH teams will estimate the amount needed for their Phase Ia/Ib clinical trials, with an expectation that the pools will be expanded for future related Phase II clinical trials. Of note, groups other than Inserm and UCPH could also benefit from established reference standards for their own vaccine development processes. The UMR216 unit of the Institut de recherche pour le développement (IRD), based in Paris, will assemble the positive pool consisting of sera from multigravid Beninese women whereas the negative pool from unexposed women will be provided by the Bichat Hospital (France).
Antibody levels by ELISA
Assessment of the vaccine-induced VAR2CSA-specific total IgG levels by ELISA is a secondary objective common to both projects. In addition to the evaluation of the amplitude of the humoral immune response elicited by vaccination, levels of VAR2CSA-specific total IgGs will also define the percentage vaccines who seroconvert, a criterion to proceed to a Phase II clinical trial. The advantages of the ELISA are its robustness and its amenability to automation, standardization and harmonization and easy transfer of protocols/standard operating procedures (SOPs) between different laboratories. ELISA has been extensively used by both teams in pre-clinical studies and was proven as adequate to detect naturally acquired human antibodies directed towards VAR2CSA-based proteins, such as the ones comprising the current vaccine candidates [27, 28].
Harmonization of the ELISA is essential in order to generate reliable and comparable data. Careful standardisation will be performed using the common reference standards and exchange of SOPs. Common blood sampling time-points will be used, at baseline (before any vaccination), 1 month after each immunization (three immunizations are scheduled at 1 month intervals), and 4 and 7 months after the last immunization. While vaccine-induced VAR2CSA-specific total IgG levels in malaria-naive subjects should be straightforward to assess, workshop attendees discussed the interfering effect of background reactivity in volunteers from malaria endemic areas. Naturally acquired antibodies directed to other, non-pregnancy related PfEMP1 variants, might cross-react with the immunizing antigens, and thereby mask the specific ELISA signal induced by vaccination. In light of this possibility, ELISA data will be interpreted with extreme care in order to draw appropriate conclusions.
A major limitation of the ELISA is nevertheless its inability to determine if the detected antibodies are functionally active and contribute to protection against placental malaria. ELISA must therefore be complemented by other techniques to properly address this issue.
Antibody inhibitory activity by CSA-binding inhibition assays
In order to facilitate the comparison of the vaccine candidates, both teams agreed to unify some functional assays. Of major importance, the CSA-binding inhibition assay (BIA) allows a qualitative analysis of the functional antibody response elicited by the vaccine candidate. The BIA assesses the capability of immune sera (more specifically of the IgG component) to block the interactions between placental type P. falciparum-infected erythrocytes and CSA.
The UCPH and Inserm teams routinely perform the well-established Petri dish BIA method as well as a high throughput technique based on the use of 96-well microtitre plates . In both approaches, CSA is coated on a plastic substrate as a platform for binding of infected erythrocytes, and BIA with sera or other inhibitors are performed under static conditions (Fig. 1). Even though the more relevant ex vivo placental perfusion model performed under flow conditions is available in both laboratories, this methodology is not yet designed for processing numerous samples and is difficult to implement under field conditions . The vaccine teams, therefore, agreed to use the Petri dish BIA method as a common reference technique to allow comparison of results between the studies. Each team will run their own 96-well microtitre plate methods in parallel as they offer the possibility to run many replicates thus increasing the statistical power of the data sets. Furthermore, the comparative analysis of both methods might allow the design/optimization and validation of a high throughput BIA that could be used in future clinical trials, such as Phase II clinical trials, when the number of samples to be processed might exceed the capacities of the classical Petri dish assay. UCPH and Inserm agreed on sharing SOPs for both types of BIA.
The choice of the P. falciparum strains to be used in the BIA has been extensively discussed between the members of the different projects. The PRIMALVAC and PAMCPH/PlacMalVac have designed their vaccines based on the 3D7-VAR2CSA and FCR3-VAR2CSA parasite strain sequences, respectively. It was obvious that both 3D7 and FCR3 strains expressing VAR2CSA should be included in the BIA. FCR3 and 3D7 [32, 33] are two well-characterized, fully sequenced, laboratory adapted cloned parasites lines. Erythrocytes infected by either FCR3 (also known as IT4) or NF54 (parental clone of 3D7) are easy to select for VAR2CSA surface expression by panning on CSA . In order to further assess the cross-inhibitory capability of antibodies generated following vaccination, a third in vitro adapted cloned parasite line, 7G8, that originates from a different part of the world (Brazil) will be included in BIA.
Fresh placental parasite isolates will also be incorporated in this analysis, as they represent parasite populations from the field sites and geographical areas where the vaccine will be implemented. Workshop attendees agreed that three fresh parasite isolates will be sufficient to extend the parasite panel used in the BIA.
For a selected subject, activity in a pre-immune sample appears be the most appropriate negative control for this type of assay. As with ELISA measurements, the investigators expect minimal background in the European samples by BIA, but inhibitory background may be present in some pre-immune samples from Africa due to existing immune responses to malarial antigens, potentially interfering with quantification of vaccine-induced responses. Aware of this possibility, both teams will interpret the generated BIA data in light of pre-existing activity.
Antibody reactivity to the surface of placental-type infected erythrocytes by flow cytometry
While antibodies that inhibit binding of placental type P. falciparum-infected erythrocytes to CSA appear to be a primary protective feature, assessing the reactivity of antibodies to the native VAR2CSA expressed at the infected red blood cell surface is also informative. Indeed, the antibody levels determined by ELISA rely on the use of recombinant proteins as target antigens and might not fully reflect reactivity to native VAR2CSA. Such analyses will also allow assessments of cross-recognition of different native VAR2CSA variants from parasites of different geographical origins. Furthermore, opsonization of infected erythrocytes could potentially trigger a variety of immune effecter mechanisms such as opsonic phagocytosis, antibody-dependent cellular cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC). Even though the relative importance of such mechanisms in protection against placental malaria is still unclear, the generated data will be useful to better understand the complexity of immune processes taking place during P. falciparum infection in pregnancy.
Both teams agreed to perform a flow cytometry-based analysis of cell surface reactivity of vaccine-induced VAR2CSA-specific IgGs to placental-type infected erythrocytes. Ideally the panel of parasite lines to be included in this type of analysis should be consistent with that used for the binding inhibition assays. Despite the use of common SOPs and due to unavoidable differences in the flow cytometry equipment, slight variations between each team’s results are anticipated.
Cell-mediated immune response
While titers of circulating vaccine antigen-specific antibodies are a robust indicator of immunogenicity and induction of humoral immune responses, this type of measurement should ideally be complemented by the assessment of cell-mediated immune responses. Enzyme-linked immunospot (ELISpot) assays are now widely used to monitor adaptive immune responses in humans and permit a quantitative as well as a qualitative analysis of T cells . In a T cell ELISpot assay, each spot represents a cytokine secreting cell allowing the determination of the frequency of T cells responding to a stimulatory antigen. The PRIMALVAC team is planning to perform T cell ELISpot to quantify cytokine-producing T cells after stimulation with the vaccinating antigen DBL1X–DBL2X. Meanwhile, the supernatant of stimulated peripheral blood mononuclear cells (PBMCs) cultures will be used for the quantification of a larger panel of cytokines using a flow cytometry-based multiplex assay. Protocols will be shared by the teams as part of the harmonization process.
Kinetics and breadth of the immune response
In terms of longitudinal assessment, a possible approach would be to follow women for at least 6 months after the last vaccine boost, and ideally until the first pregnancy. An ongoing baseline study in Benin is suggesting that as many as 25 % of women could become pregnant within 12 months after enrollment, and that 30–40 % of them are likely to be infected with P. falciparum during pregnancy. Therefore a careful design and sufficient additional funds for the follow-up studies for both clinical trials (PRIMALVAC and PlacMalVac) will be required to study the natural boosting effects. To study the breadth of the immune response, the B cell memory immune response will either be assessed using a B cell ELISpot assay or by performing B cell phenotyping as exploratory endpoints. A summary of the immunoassays to be performed in each of the projects is provided in Tables 3 and 4.
Discussion and conclusion
Currently, treatment and prevention of placental malaria relies on the use of long-lasting insecticide-impregnated nets and sulfadoxine–pyrimethamine (SP)-based IPTp strategies. Resistance of parasites to drugs and of mosquitoes to insecticides, are increasingly compromising the effectiveness of these tools. In addition, placental malaria is very often sub-clinical, with parasitaemia at very low (sub-microscopic) levels, such that pregnant women often remain unaware of their infection and do not seek treatment. At their first antenatal visit, and therefore their first SP dose, many pregnant women have already sustained infections and suffered sequelae of placental malaria. Further, SP is contraindicated in the first weeks and months of pregnancy due to potentially serious clinical consequences for the fetus. Looking forward, the costs and logistical challenges of mass drug administration to pregnant women cannot be ignored and new methods for malaria control during pregnancy urgently need to be explored.
A malaria vaccine that rapidly controls blood-stage infection and prevents sequelae would be an excellent tool to protect women against placental malaria. GlaxoSmithKline’s RTS,S/AS01 (Mosquirix™) by far the most advanced malaria vaccine, has been developed for administration to children. RTS,S/AS01 provides about 36 % protection against blood-stage infections and clinical malaria over 1 year to children aged 5–17 months at first immunization but vaccine efficacy fell to less than 5 % from the fourth year [36–39]. The protection is short-lived, waning over some months as antibody levels rapidly decline after vaccination. Even if RTS,S/AS01 were developed for pregnant women, it only confers partial protection in children and perhaps less in adults, so its potential activity against placental malaria is uncertain. Additional tools are required to combat placental malaria. Vaccines designed specifically for placental malaria are attractive because they could lead to reductions both in disease incidence and severity.
The two placental malaria vaccine candidates, PAMVAC and PRIMVAC adjuvanted with Alhydrogel (Brenntag, Denmark), GLA-SE or GLA-LSQ (IDRI, USA) entered Phase Ia/b clinical trials in May 2016 (NCT02647489, NCT02658253). To allow comparison of the clinical trial results and to enable informed decision making for further development, two workshops were conducted by EVI with the aim of standardizing and harmonizing the clinical development plans and the immunoassays for assessing responses to the two placental malaria vaccine candidates. The workshop on clinical development defined the main preferred product characteristics, the clinical development plan and in more detail the design of the Phase Ia/b clinical trials. The second workshop on immunoassay harmonization targeted the definition of reference reagents and standards to be used to evaluate vaccine candidate performance. Harmonized ELISA will be performed to assess antibody levels generated by vaccination and the criterion for transition to Phase II requires at least 60 % seroconversion against the vaccine candidate antigen in the target population. Exploratory objectives include the analyses of the (1) antibody inhibitory activity in CSA-binding inhibition assays, (2) antibody reactivity to the surface of placental-type infected erythrocytes by flow cytometry, (3) cell-mediated immune response, and (4) kinetics and breadth of the immune response.
The results of the Phase Ia/b clinical trials for the two vaccine candidates will be used to further refine and optimize the Phase IIb clinical trial design. Evaluation criteria for Phase IIb efficacy testing will be set according to the Phase Ia/b clinical trial results, the results of on-going baseline study in Benin, planned anti-malarial drug trials to evaluate different drug regimens in placental malaria, as well as results of studies performed by NIH in collaboration with the EVI, Inserm and UCPH teams to validate an Aotus monkey placental malaria model. In Phase II clinical trials, pregnant women will be followed as recommended by the respective Ministries of Health, and blood samples for immunological analyses will be collected at each antenatal visit and at delivery. Evaluation criteria will take into account maternal disease and birth outcomes. Rather than proceeding directly to large Phase IIb efficacy trials upon satisfactory safety and immunogenicity results in the Phase Ia/b clinical trials, a Phase Ib–IIb bridging clinical trial without an efficacy endpoint might be considered to optimize vaccine dosage. This would allow studies of (1) the longevity of the induced antibody response, (2) the need for a booster immunization, (3) the extent to which a long-lasting antibody response targets different VAR2CSA antigenic variants, (4) the duration of the memory response that can be boosted by infection; and (5) the utility of a prime-boost or association regimen in eliciting a broader immune response in vaccinated women after natural infection.
In summary, the development of placental malaria vaccines will require continuous collaboration, standardization and harmonization among the teams to allow the further development of the most suitable and best performing vaccine candidate.
antibody-dependent cellular cytotoxicity
binding inhibition assay
complement dependent cytotoxicity
cysteine-rich interdomain region
chondroitin sulfate A
enzyme linked immuno-sorbent assay
European Vaccine Initiative
glucopyranosyl lipid A-stable emulsion
glucopyranosyl lipid adjuvant-liposome-QS-21 formulation
human hepatitis B virus
human hepatitis C virus
human immunodeficiency virus
human papilloma virus
Institut National de la Santé et de la Recherche Médicale
intermittent preventive treatment during pregnancy
- iRBCPM :
infected red blood cells placental malaria (PM) phenotype
Institut de recherche pour le développement
National Institutes of Health
peripheral blood mononuclear cells
Plasmodium falciparum erythrocyte membrane protein 1
GSK’s malaria vaccine candidate RTS,S adjuvanted with AS01 (also known as Mosquirix™)
Drosophila melanogaster Schneider-2 cells
standard operating procedure
University of Copenhagen
World Health Organization
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Clausen TM, Christoffersen S, Dahlback M, Langkilde AE, Jensen KE, Resende M, et al. Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria. J Biol Chem. 2012;287:23332–45.
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Gamain B, Trimnell AR, Scheidig C, Scherf A, Miller LH, Smith JD. Identification of multiple chondroitin sulfate A (CSA)-binding domains in the var2CSA gene transcribed in CSA-binding parasites. J Infect Dis. 2005;191:1010–3.
Duffy PE, Fried M. Antibodies that inhibit Plasmodium falciparum adhesion to chondroitin sulfate A are associated with increased birth weight and the gestational age of newborns. Infect Immun. 2003;71:6620–3.
Dechavanne S, Srivastava A, Gangnard S, Nunes-Silva S, Dechavanne C, Fievet N, et al. Parity-dependent recognition of DBL1X-3X suggests an important role of the VAR2CSA high-affinity CSA-binding region in the development of the humoral response against placental malaria. Infect Immun. 2015;83:2466–74.
Fried M, Avril M, Chaturvedi R, Fernandez P, Lograsso J, Narum D, et al. Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria. Infect Immun. 2013;81:487–95.
Saveria T, Duffy PE, Fried M. Evaluation of pregnancy malaria vaccine candidates: the binding inhibition assay. Methods Mol Biol. 2015;1325:231–9.
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Pehrson C, Mathiesen L, Heno KK, Salanti A, Resende M, Dzikowski R, et al. Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria. Malar J. 2016;15:292.
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AC and NKV contributed to the drafting of the report. All authors attended the workshops and revised the manuscript. All authors read and approved the final manuscript.
Scientific Oversight Committee Clinical development WS: Adrian J.F. Luty, Institut de recherche pour le développement (IRD), France; Alister Craig, Liverpool School of Tropical Medicine, UK; Odile Launay, Centre d’Investigation Clinique (CIC) Cochin-Pasteur, France; Patrick Duffy, National Institute of Allergy and Infectious Diseases/National Institutes of Health, USA.
Scientific Oversight Committee Immunoassay WS: Patrick Duffy, National Institute of Allergy and Infectious Diseases/National Institutes of Health; Carole Long, National Institute of Allergy and Infectious Diseases/National Institutes of Health; James Robertson, Independent advisor, previously at the National Institute for Biological Standards and Control (NIBSC).
The authors would like to thank all workshop participants for their discussions during the workshop and Thor G. Theander and Nathalie Imbault for critically reviewing of the manuscript and Marilou Tétard for providing Fig. 1.
The authors declare that they have no competing interests.
Availability of data and material
The original workshop reports are available upon request through the European Vaccine Initiative via email@example.com.
Main financial support for the workshop was provided by the German Federal Ministry of Education and Research (BMBF) through KfW and the Irish Aid. Support was also provided by the EU Seventh Framework Programme under Grant Agreement No 304815 (PlacMalVac) and the Danish National Advanced Technology Foundation.
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Cite this article
Chêne, A., Houard, S., Nielsen, M.A. et al. Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report. Malar J 15, 476 (2016). https://doi.org/10.1186/s12936-016-1527-8
- Placental malaria
- Vaccine development
- Clinical trial | <urn:uuid:ac9e7bdf-e167-4ba5-8e6e-10e93767ecc9> | CC-MAIN-2022-33 | https://malariajournal.biomedcentral.com/articles/10.1186/s12936-016-1527-8 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.890901 | 10,793 | 2.421875 | 2 |
عنوان مقاله [English]
In the present study, the effect of different levels of dietary nucleotides (Vanazhen) as a food attractant on the growth rate and feeding rate of Persian sturgeon (Acipenser persicus) were studied. Fish with an average weight of 42/37 ± 2/12 g and mean length of 23/67 ± 0/61 cm were divided to 4 treatments with different levels of nucleotides in the diet (0, 0/25, 0/35 and 0/50%) with three replications containing 12 fish per tank. After 10 weeks feeding, survival, growth and feeding indices such as weight gain, specific growth rate, condition index, feed conversion and feed efficiency ratio were examined and the significance of them were analyzed using One-way ANOVA analysis software Spss 18. The best results in terms of weight and length compared to the weight gain, feed conversion ratio, specific growth rate and feed efficiency ratio from treatment 2 (0/35% of the nucleotides). This study showed that adding nucleotides to increase food intake, reduce food losses and thus increase the growth rate of sturgeon. | <urn:uuid:5d53ea5c-c7b3-4b27-93b3-dc1c407e528d> | CC-MAIN-2022-33 | https://www.aejournal.ir/article_96652.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.927272 | 311 | 2.703125 | 3 |
When NATO talks about Crimea, in the vast majority of cases the people of Crimea go unmentioned. Here, a parliamentarian and a political scientist from the Russian peninsula have their say. They comment on NATO’s plan to “take care” of the Black Sea region even more.
The NATO leadership accuses Russia of growing militarily stronger in Crimea. The alliance must react to this and show even more presence in the Black Sea region, NATO Secretary General Jens Stoltenberg said recently. At the same time, he called on NATO member states to continue spending money on armaments. Measures to strengthen the military alliance are to be presented at the 2021 annual summit.
In an interview with RIA Novosti, Yefim Fix, vice chairman of the regional parliament of the Republic of Crimea, responded that Russia was solely concerned with protecting its borders. NATO, meanwhile, was doing everything it could to build up risks and dangers along foreign borders, he said.
“Russia secures its borders on its own territory. At the same time, NATO, led by the U.S., is not missing any opportunity to deploy its own forces as close as possible to Russia’s borders What security policy decisions Russia makes in the process is an internal Russian matter. NATO has to keep its nose out of it,” the parliamentarian said. Otherwise, what NATO is doing could also be seen as “preparing a military attack on Russian territory,” the politician adds.The political scientist also attributes Jens Stoltenberg’s announcement regarding the Black Sea region to the change of power in Washington: “It is almost certain that Joe Biden will exert a stronger influence on Eastern Europe. This includes stronger military cooperation with Ukraine and Georgia – with the aim of pressing Russia further. A futile plan, by the way.”
The Republic of Crimea has been a Russian region again since March 2014. At that time, a good 96 percent of all voters in Crimea voted in a referendum to unite the peninsula with Russia. Before that, a violent power coup had taken place in the Ukrainian capital Kiev. The Russian leadership stated several times that the people of Crimea had voted in favor of unification with Russia in a democratic process in accordance with international law and the United Nations statute. According to the Russian president, this “conclusively settles” the Crimean issue. (RN)
by Xavier Cuesta – European Correspondent | <urn:uuid:90e18b49-d9a8-4ead-853f-f918d434d061> | CC-MAIN-2022-33 | https://iuvmpress.news/nato-has-to-stay-out-of-this/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.963039 | 499 | 1.820313 | 2 |
In this Great Game Victory Day special, V and Matt break down the ugly fact that WW2 was never truly won in 1945 as many have been falsely led to believe. The reason for this ugly fact is simply that the prime movers behind the rise of fascism during the 1920s-1930s not only went unpunished in Nuremberg, but continue to exert a vast influence on the Trans Atlantic community to this day.
Or watch on Bitchute here
Matthew Ehret is the Editor-in-Chief of the Canadian Patriot Review , and Senior Fellow at the American University in Moscow. He is author of the ‘Untold History of Canada’ book series and Clash of the Two Americas trilogy. In 2019 he co-founded the Montreal-based Rising Tide Foundation . | <urn:uuid:3bd35c51-f110-4fe9-a314-6164fe12acf7> | CC-MAIN-2022-33 | https://canadianpatriot.org/2022/05/10/the-great-game-this-week-the-ugly-truth-of-ww2-and-the-roots-of-the-great-reset/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573876.92/warc/CC-MAIN-20220820012448-20220820042448-00072.warc.gz | en | 0.966194 | 160 | 1.679688 | 2 |
Within two and a half weeks of each other late last year, three big-name pharmaceutical companies—Pfizer (working with BioNTech), Moderna, and AstraZeneca—produced viable COVID-19 vaccine candidates. When it was reported that the Pfizer vaccine had to be kept at a frigid -70 °C, many experts predicted its difficult storage requirements would pose a distribution challenge that inevitably could lead to waste.
Another area of concern lies in the food industry where the United States has been established as the global leader in food waste. It’s been reported that Americans discard nearly 40 million tons of food every year. That’s 80 billion pounds of food which equates to 30-40 percent of the country’s food supply. And while personal food waste is a leading contributor to these disturbing numbers, approximately 12 percent of all food waste occurs during distribution when room temperature changes often take place.
Both the pharmaceutical and food & beverage industries are part of what’s known as cold chain logistics. Temperature-sensitive products like chemicals, meat, plants, drugs and vaccines require temperature-controlled environments from production to consumption and every step in between. Temperature consistency ensures the quality of these products as they move through their respective supply chains. Unfortunately, ensuring temperature consistency is often challenging.
The good news is that determining whether consistent temperatures have been effectively maintained is much easier today due to advancements in the cold chain itself as well evolving technology and tracking capabilities.
Temperature monitoring can save the pharmaceutical and food & beverage industries thousands of dollars per year in lost or spoiled goods. With a temperature monitoring system in place, distribution fleets can keep an accurate record of temperatures within trucks in order to prevent lost loads and maintain high quality customer service.
Wirelessly Monitor Up To Four Refrigerated Zones At A Time
Advantage Asset Tracking’s Temperature Monitoring ELD add-in, Advantage TempTrac, has been specifically engineered to help meet today’s demanding temperature-sensitive delivery requirements by allowing drivers to customize temperature ranges based on the type of load they are hauling. Whether it be fresh produce, frozen goods, or high-value assets such as pharmaceuticals, Advantage TempTrac ensures accurate, reliable and safe deliveries by displaying current and historical temperatures in the Geotab Drive ELD app with visual and audible alerts if the temperature goes outside of the temperature range for the type of load their hauling.
Compliance Made Easy
Our solution can facilitate Food Safety Modernization Act (FSMA) compliance as it monitors up to four zones simultaneously, and can be operated either as a stand-alone solution or seamlessly integrated through Geotab’s GO Device. From there, integration into the MyGeotab fleet tracking system allows fleet managers to monitor vehicle location and cargo temperature from one convenient platform.
How It Works
Advantage TempTrac uses four simple components to create one complete temperature monitoring solution. Once installed, monitoring temperature is as simple as it is effective. The diagram below indicates a typical setup on a reefer truck.
Cold chain compliant (US FSMA, EU EN12830)
Real-time monitoring of temperature inside the trailer, every 4 seconds
Immediate SMS or email alerts for over and under temperature changes
Track temperatures through the life of a shipment and trend temperatures over time
Wirelessly monitor up to 4 zones in real time (additional sensors sold separately)
Real-time monitoring removes the need for manual temperature inspection
Prevent spoilage of temperature sensitive loads
Reduce liability and number of rejected goods due to spoilage
Improved visibility on high value shipments through fleet tracking
To learn more about how Advantage Asset Tracking’s temperature monitoring system can help your fleet, reach out for a demo today.
In the U.S., ELDs are now mandatory for most commercial motor vehicle drivers to manage records of duty status (RODs), with Canada not far behind in needing to observe this requirement. The government mandates are intended to create a safer work environment for drivers. Naturally, any new implementation will yield questions from its users. Here are the most-asked questions on ELD compliance to help you save time:
1. How do you edit the HOS status Logs in Geotab Drive and MyGeotab?
In the Geotab Drive Mobile App, you can easily record HOS status and perform vehicle inspections using a phone or tablet.
If you need to edit your HOS status log:
Go to the dashboard and click HOS > Logs
Then tap the log you need to edit.
To select the appropriate status select the Pencil icon.
Add an annotation and hit Save.
Keep in mind, automatic HOS logs can be annotated, but not edited. For more information, and a full breakdown of instructions, read: How to edit HOS status logs in Geotab Drive.
Fleet managers can also edit HOS Status Logs from MyGeotab.
Go to Activity > HOS > Duty Status Logs
Select the driver and date period.
Tap Apply Changes.
Click the duty status that needs editing.
Select the appropriate status from the Status dropdown list.
Add an annotation and hit Save.
A pending edit has been created, and will show in yellow until accepted by the driver.
2. How does a driver log into the Geotab Drive App?
Logging into the Geotab Drive App is simple.
First, enter your username and password and select Log in. The system will synchronize your data before loading the main interface.
Select your vehicle. You can review recently driven vehicles in the Suggested Vehicles tab, or search by vehicle name, VIN, or license plate in the Find Vehicles box. (This step is skipped when connected to IOX-USB). If you do not know which vehicle you will be driving, click No Vehicle.
The next screen in an Assets screen. Select trailers by clicking the + icon next to Trailers, then select a trailer from the list. To add a new trailer, type its name into the Find Trailers box and then click Add. When you are finished selecting trailers click Continue.
To add a new shipment, tap the + icon next to Shipments, and then enter the shipment details, then hit Add. When you are finished selecting shipments click Continue. Remove any assets by clicking the X icon.
Hit Save and Continue once you are done selecting assets.
For a step-by-step walkthrough of these steps and further settings, such as how to add annotations, complete DVIR inspection, or how to view pending Log edits, watch the video below.
3. How do you pull an IFTA report?
Users can easily pull an International Fuel Tax Agreement (IFTA) mileage report from MyGeotab. After logging in, go to Activity and then scroll down to the IFTA Report option.
4. How do you apply Personal Conveyance?
In Geotab Drive, you can find Personal Conveyance by going through HOS > View Exemptions on the dashboard. If you do not see Personal Conveyance within View Exemptions, please reach out to an administrator to enable this feature.
Of course, we are ready to help anyone new to ELDs make a smooth and easy transition.
Contact us today at (888) 680-5833 or email@example.com.
Join Us for Our Very First Happy Magic Hour!
Help us fight off the winter blues with an hour of family-friendly fun with Comedy Magician, Erick Olson! This free virtual event will take place on Thursday, March 11th @4:30pm EST.
As seen on America’s Got Talent, Erick Olson is a cross between Jay Leno and David Copperfield with amazing magic, comedy, visual gags and quick one-liners. Erick’s action packed show is fantastically entertaining and will keep you hooked all throughout.
Advantage Asset Tracking wants you to get a great laugh and big cheer right before the weekend. If you like magic, Erick’s show will leave you scratching your head and asking “How did he do that?”
This free event will take place LIVE on Thursday, March 11th @4:30pm EST.
Click HERE TO REGISTER for the event.
We have been posting a number of blogs on the electrification of fleets across industries with an emphasis on the heavy-duty fleet sector. Without a doubt, the electrification in transportation is an inevitability and with reason: not only does it lead to technological advances that increase efficiency but it also offers an essential response to environmental and sustainability concerns.
We covered both the barriers and benefits of the electrification of heavy-duty fleets in our last blog post (link to Blog Post C). Now we turn our attention to the implications of adding electric models to heavy diesel industries, among other updates on the advancement of heavy-duty fleet electrification.
Air Quality and Health
Much of the air pollution in lower-income communities comes from the diesel trucks that move products to and from nearby industrial areas. Diesel emissions are also a major source of nitrogen dioxide which prevents these areas from achieving air quality levels necessary for good public health. The state of California estimates that their new electric truck mandate could prevent 900 premature deaths in these communities and deliver $9 million in public health benefits.
Impact to Grid
Electrification of the heavy-duty sector presents unique challenges and opportunities compared to light-duty EVs. With considerably larger batteries and higher charging rates, if left unmanaged, charging heavy-duty vehicles could have negative impacts on the grid. However, implementing smart charging systems can reduce these impacts. Mechanisms such as off-peak electricity demand charging, dynamic controlled charging and vehicle-to-grid (V2G) could all help to mitigate the impact of electric trucks (eTrucks) and electric buses (eBuses) on peak demand and reduce electricity generation capacity needs.
Oil Demand and GHG Emissions
Even though trucks represent less than 5% of the global vehicle stock, their high fuel consumption and mileage means that they are responsible for over a third of global diesel demand and 3% of total global energy demand. The electrification of these trucks would therefore have a significant impact on overall diesel and oil demand. Across all vehicle weights, it is estimated that EVs will displace 4.3 million barrels of oil per day by 2030. GHG emissions are closely related to fuel consumption, and medium- and heavy-duty trucks are responsible for a sizable share of total GHG emissions. As diesel drivetrains give way to electric, the resulting fall in GHG emissions will be considerable.
Government interventions to accelerate the transition of heavy-duty transport to electric
California is the first state to approve specific legislation to accelerate a large-scale transition of zero-emission medium- and heavy-duty vehicles. The Advanced Clean Trucks (ACT) Regulation was passed by the California Air Resources Board to help the state meet its mandates to reduce air pollutants, in order to protect public health and meet climate change targets.
The regulation requires that manufacturers who certify Class 2b-8 chassis or complete vehicles with combustion engines would be required to sell zero-emission trucks as an increasing percentage of their annual California sales from 2024 to 2035.
Seven other states and the District of Columbia have signed a statement of intent to pursue a similar medium- and heavy-duty zero emission vehicle initiative.
The importance of varied EV model support for complete fleet management
As fleet and sustainability managers make their long-term plans for fleet electrification, it’s vital to select a fleet management platform that can support the greatest range of makes / models, and that has the capabilities to accommodate the most new EVs as they come to market.
Geotab has been independently ranked as the number one commercial telematics vendor for two years running. And with support for over 100 electric vehicles, it’s the strongest telematics provider in the EV space.
It’s likely that managers will initially have to operate a fleet consisting of both electric and conventional vehicles. The fleet management platform must therefore be able to work with all drivetrains, so that performance data such as mpg and mpg-e can be directly compared. The platform also needs to be able to collect electric-only data such as battery state of charge, to ensure optimal performance and maximum ROI during the transition to an all-electric fleet.
Our Geotab fleet management platform offers the widest make / model support of all EVs, from light- to heavy-duty, to support your fleet today and into tomorrow.
In a recent blog post we talked about the five electric commercial truck companies we are watching in 2021. Today we will go deeper into the latest trends we are seeing in the heavy-duty fleet category. Although this segment of the commercial vehicle market is still young, the world’s largest manufacturers have made it clear that they see electrification as an increasingly important piece of the freight transportation industry.
Just in the past few years, we have started to see an increase in market share of electric trucks (eTrucks) and electric buses (eBuses). Most of the major Original Equipment Manufacturers (OEMs) and several start-ups are preparing to launch their respective battery electric or fuel-cell/battery models in 2021/22, and the electric bus market is already well established in the U.S. With the early adoption of EVs, fleet and sustainability managers can get ahead of stringent emission regulations, which will make it inevitable that transit agencies, school districts and logistics companies deploy cleaner fleets.
Barriers (and Benefits) to Electrification in the Heavy-duty Sector
With such new technology, naturally there will be challenges to adoption. We note the most obvious ones below. We also highlight some of the benefits to adopting electrification in the heavy-duty sector as these certainly will offset the barriers through further technological advances and challenges being addressed.
One of the greatest challenges facing heavy-duty electric vehicles is range. Trucks are intended to haul heavy trailers and loads, which are demanding tasks that contribute to quick battery drain. Load weight is another consideration in the heavy-duty sector. The benefits of eTrucks will certainly depend on load weight as a factor, as it can potentially result in higher electricity consumption and shorter range capability. Load capacity claims from OEMs suggest that they will be capable of matching today’s load standards, but they will require real-world data to prove this out.
In order to counter the issue of range, manufacturers currently have to use larger, or more, batteries. The larger the battery capacity, the longer it takes to charge. Most eTrucks will take well over two hours to fully recharge on the fastest available charging systems, and some vehicles will have to plug in overnight to fully recharge a drained battery.
For a given GCWR (gross combined weight rating), electric trucks can’t carry as large a payload as their diesel counterparts, because their tractor weighs significantly more. This can leave the trucks with a several thousand pound shortfall in carrying capacity. This results in logistics companies needing more eTrucks to do the same amount of work as their conventional alternatives.
Now let’s look at the benefits of an electrified heavy-duty sector:
A feature that’s unique to eTrucks is instant torque, or the ability to deliver peak torque at zero RPM. This enables electric trucks to tow and haul a large payload at much lower speeds than their conventional counterparts.
Reduced maintenance requirements
Although pure electric vehicles require some scheduled maintenance for their electrical systems, this is minimal compared to that required for their ICE counterparts. This is because a pure electric vehicle has far fewer moving parts than a combustion engine, and no oil or transmission fluids to replace. Brake systems also last longer than for conventional vehicles, thanks to their regenerative braking systems.
Environmental noise reduction
While rolling noise remains a constant when comparing electric heavy-duty vehicles with their ICE counterparts, the propulsion noise is considerably lower without a combustion engine. This makes the biggest impact when vehicles operate at low speeds, as they most frequently do in urban areas, where noise pollution is the greatest concern.
Reduced Total Cost of Ownership (TCO)
In the U.S. long haul market, McKinsey predicts that medium- and heavy-duty trucks will reach TCO parity with diesel in the early 2030s. In urban operations, light-duty trucks and eBuses will have achieved parity by 2025, and medium-duty trucks pre 2030.
In our next blog post, we will cover the implications of adding more electric models to heavy diesel industries and the importance of EV model supports for successful fleet management transitions. | <urn:uuid:63e50539-20db-4a7c-a0cd-35b24470a217> | CC-MAIN-2022-33 | https://www.advantageone.tech/2021/02/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573876.92/warc/CC-MAIN-20220820012448-20220820042448-00072.warc.gz | en | 0.931987 | 3,536 | 2.421875 | 2 |
As you were. The United Kingdom remains united, with Scots rejecting independence by an unexpectedly large margin of 55% to 45%. The “No” (to independence) campaign prevailed in 28 of Scotland’s 32 local council areas.
“There can be no disputes, no re-runs,” said British prime minister David Cameron. “Now the debate has been settled for a generation.”
Less than half of Scots agree. In a post-referendum survey by the pollster Lord Ashcroft, 43% of voters said they believed that the question of whether Scotland should be independent or remain a part of the UK will remain settled “for the next generation” (24%) or “forever” (19%). A somewhat larger group, 48%, said that the independence issue has been put to bed for the next ten years, at most.
The referendum allowed 16- and 17-year-olds to vote for the first time, and they chose “Yes” by a huge margin, according to Lord Ashcroft’s poll. But older voters were just as enthusiastically opposed to independence, which proved decisive:
On the question of whether Scotland will make another run at independence in the near future, the views of younger voters carry more weight—and two-thirds of 16- and 17-year-olds think that the independence issue will only remain settled for a decade or less. This could set Scotland up for a “neverendum” scenario—a term coined to describe Quebec’s ongoing flirtation with secession from Canada despite two failed votes on independence, in 1980 and 1995.
Alex Salmond, head of the Scottish National Party and leader of the pro-independence campaign, announced his resignation today. He thanked the 1.6 million voters who backed independence, and expressed some skepticism about the British government’s promise to give Scotland more powers. “For Scotland, the campaign continues and the dream shall never die,” he said. | <urn:uuid:28f537c8-e5cb-4a63-a649-da0720104f2f> | CC-MAIN-2022-33 | https://qz.com/268508/for-voters-on-the-losing-side-scotlands-no-is-more-like-no-for-now/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.962273 | 414 | 2.578125 | 3 |
Doctors successfully transplanted the heart of a pig into a patient suffering from chronic heart disease to save his life. 3 days just after an extraordinarily experimental procedure, the Maryland hospital where David Bennett was just being operated on stated on Monday that he is doing fine. Although it would be too early to say if the procedure will succeed, it's an important step forward in the years' goal to one-day employ organs of animals for life-saving surgeries.
Man Gets Genetically Modified Pig Heart In A World-first Transplant
The very first successful transplantation of a genetically altered porcine heart into a human patient was revealed recently by the University of Maryland Medical Center (UMMC) and the University of Maryland School of Medicine (UMSOM). Following the historic operation on 7th January 2022, to save his life, the patient of a heart transplant, a 57-year-old male, is doing well.
For the very first time, a genetically altered animal heart was capable of functioning like just a human heart without being rejected by the body. The recipient, David Bennett, will be closely examined over the coming days to see if the transplantation has saved his life.
"It Was either do this transplant or die," says the patient. I wish to live. Bennett remarked just before the operation, "I realize it's a shot in the dark, but it's my final resort." For the previous several weeks, he had been bedridden and hospitalized. "I can't wait to get out of bed once I've recovered."
The United States Food and Drug Administration (FDA) does not permit porcine heart transplants; nonetheless, the Food and Drug Administration approved the procedure throughout this case for "considerate use" because the patient had no other choices.
This medical development might aid healthcare providers in resolving the situation of organ shortage that prevents thousands of people from receiving life-saving heart surgery every year. Approximately 20% of people on the waiting list for heart transplants die while waiting for a transplant or grow too ill to be viable targets candidates for the complicated surgery.
A donor's heart is usually matched to the patient's body size and blood type. Patients who have had a heart transplant should take drugs to keep their immune systems from the rejection of the new organ. Immunosuppressives are medications that prevent the heart transplant from being rejected by reducing the body's natural immunological reaction to unwanted material. These medications, nonetheless, could have adverse effects, such as infections or an elevated chance of certain tumors. | <urn:uuid:0229af16-1c5b-4fa6-aed4-58d4d3941c68> | CC-MAIN-2022-33 | https://www.thatviralfeed.com/man-gets-genetically-modified-pig-heart-in-a-world-first-transplant/98672/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.956495 | 514 | 2.3125 | 2 |
Why Global Health Photography?
As our world becomes increasingly connected, there is a growing realization that public health challenges are global. Disease doesn’t respect international borders. Poverty doesn’t simply diminish the lives of citizens of underdeveloped nations. In a globally connected world, poverty and disease and underdevelopment threaten us all.
The global health revolution is fueled by that fundamental realization. Global public health needs are being defined and prioritized, resources are being acquired and dedicated, and lives are being reclaimed and restored.
Public Health: An Immense Challenge Ahead
But the challenges are immense. Improving lives on this vast scale takes tremendous amounts of time, money and persuasive skill. Stakeholders need to be informed. Impact statements prepared and approved. Presentations made, capital raised.
In short, compelling stories need to be told and retold, until that politician, that software developer, that banker, that grant administrator, that senator, that global health care researcher, that individual donor — until all of them are nodding their collective heads, gathering together, targeting the challenges, and saving lives.
Global Health Photo was founded for this purpose:
To provide private and public sector organizations with the documentary photographic resources necessary to communicate complex, large-scale stories in support of the global health revolution.
- Neglected Tropical Diseases (NTDs)
- Non-communicable diseases (NCDs)
- Maternal, newborn and child health (MNCH)
- Family planning and reproductive health (FP/RH)
- Water, sanitation and hygiene | <urn:uuid:f7cdb4c7-c7bf-440a-8510-692440348ce9> | CC-MAIN-2022-33 | https://www.globalhealthphoto.com/rationale/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573399.40/warc/CC-MAIN-20220818185216-20220818215216-00072.warc.gz | en | 0.921849 | 336 | 2.375 | 2 |
History shows that a growing centralization of power and economic decline can accelerate emigration. Canada is witnessing both.
In democracies, we tend to think of elections as the most profound statement we make as Citizens when it comes to the direction of the nation.
And while that is largely true, there is another way people send a message about the policies of those in power:
And when we look around the world, we can see that inflows and outflows of people from a country are based on two main factors:
First, there is the immigration policy of a country.
Second is the level of freedom and potential economic prosperity within a country.
For example, while the United States receives a large number of immigrants (both legal and illegal) every year, that number would be far higher if the US government set a higher threshold, since there is high demand among people around the world to be in America.
Similarly, many people try to leave parts of Africa and the Middle East in order to get to Europe, where standards of living are much higher, and human rights/property rights are more protected.
Most dramatically, we can see people fleeing in Ukraine in order to escape war, and to avoid being put under the governance of the authoritarian Russian government.
When given the option, people flee to where they can be free and where their chance to gain prosperity is higher.
Immigration brings many positives, as countries like Canada and the United States have learned. Of course, no country can let in an unlimited amount of people, and there are downsides when immigration levels exceed the capacity of a country to manage, leading to both economic difficulty and division.
That said, the fact that there is such high demand for the ability to live in this country is a complement to the kind of nation we’ve built over Canada’s history.
When people ‘vote with their feet’ by leaving one country for another, it says a lot about both nations.
And it’s why some recent trends in Canada are cause for significant concern.
Two recent stories by Better Dwelling delve into the statistics to reveal that emigration in Q4 of 2021 reached levels not seen since the 1970s, and that a rising number of new Canadians are considering leaving this country.
For 2021, emigration reached the highest level since 2016. However, as noted by Better Dwelling, the highlight number is emigration in the 4th quarter of 2022:
“Canadians are packing up and leaving at a fast rate, during a traditionally slow period. Statistics Canada (Stat Can) data shows emigration, the act of leaving permanently, jumped in 2021. The past year showed modest gains, rising to the highest level in half a decade. The fourth quarter is what sticks out though, showing a sudden acceleration. Canada saw the largest Q4 volumes of residents leaving since the 1970s.
Canadians left the country at a swift pace in a quarter they usually don’t plan a move. Stat Can estimates 16,901 emigrants in Q4 2021, up 215% from a year before. Annual growth doesn’t mean much, due to the outbreak’s base-effect. Don’t let the distortion allow you to dismiss the whole trend though.
Looking at the longer term, this was a huge fourth quarter. The Q4 2021 emigration was still 55.7% higher than the 5-year median for the quarter prior to 2020. It also happens to be the biggest Q4 for people leaving since 1974.”
In addition to those who have already left, many are considering leaving:
Recent immigrants considering emigration
As Better Dwelling notes, “Canada’s general population underestimates the impact high living costs have on immigration. Less than a third (31%) feel a high cost of living would prevent immigrants from staying in Canada. New Canadians feel very different, with the majority (64%) feeling a high cost of living is an issue. A bit at odds with the investment thesis on immigration maintaining high levels, despite the cost of living.”
Many are now considering leaving:
“A lot of new Canadians are considering leaving the country within two years. The survey found 22% of new Canadians are considering leaving within two years. Another 21% were neutral, and undecided on how they currently feel. The remaining 57% said it was unlikely they’ll move. A majority is unlikely to move, but this is still a significant outflow. If those immigrating to Canada face similar issues driving people to leave, eventually immigrants just move to wherever those leaving head.
“Canada is a nation of immigrants — and one of the stories we tell ourselves is that we are welcoming to new immigrants, wherever they may be from,” says ICC CEO Daniel Bernhard. “But while this may be generally true, new survey data points to the fact that many new Canadians are having a crisis of confidence in Canada — and that should be ringing alarm bells all over Ottawa.””
Creeping authoritarianism & economic stagnation
So, what has changed in this country that is driving more people to consider leaving?
Given that a desire for freedom and economic progress are the driving force behind many who seek to come live here, it stands to reason that when those things start to erode there will be an increase in those who want to leave.
And when we look at the policies of the Liberal government, we can see how the state is becoming larger and more powerful, while our economy stagnates.
During the pandemic, the Liberal government imposed some of the more draconian measures seen in ‘free nations,’ and even now continues to impose restrictions on unvaccinated individuals.
Legislation like Bill C-11 would expand the control of government over the internet, and shows the ongoing hostility of the Trudeau government to free and open debate.
Combine that with an economic policy that is based on tax increases, inflationary measures, increased regulations, and mentality hostile to business, and it’s no surprise that Canada no longer feels as free and prosperous as it once did.
Another issue facing Canada is that due to our weather we have to offer something more, when compared to countries like the United States or Australia.
Canada can be a beacon of hope and opportunity to many around the world, but only if we are a country that respects individual rights and freedoms, limits the power of government, and frees people to innovate, create, build businesses, and achieve their dreams.
Clearly, that’s not the course our nation is on right now, and unless that changes we can expect more and more people to seek their future elsewhere.
Photo – YouTube | <urn:uuid:be9f68a5-da0e-4aea-866b-6a818d331c28> | CC-MAIN-2022-33 | https://spencerfernando.com/2022/03/29/canadians-voting-with-their-feet-as-emigration-surges-more-new-canadians-think-of-leaving/?mc_cid=dbdc3eee96&mc_eid=9e81ba242d | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.962159 | 1,396 | 2.578125 | 3 |
The 10-Year Treasury Yield dropped almost 4/10% recently – so why didn’t mortgage rates drop that much?
The 10-Year Treasury yield (interest rate) is a reflection of what it costs the government to borrow money and is perhaps the most influential interest rate/yield in the world.
Hence, when the 10-Year yield drops, the media will widely report that rates are falling, which prompts borrowers to think that mortgage rates are falling.
This happened recently as the 10-Year yield dropped from almost 1.7% in late November to almost 1.3% in early December.
Plummeting 10-Year yields sparked “RATES ARE FALLING” headlines but mortgage rates barely moved.
Hence, it is important to note that while mortgage rates usually move in unison with 10-Year rates, they do not always do so.
In the “olden days” (the 1990s) when we had to call up the “Bond Market Hotline” on the telephone to see what rates were doing, a 4/10% drop in the 10-Year Treasury could have resulted in as much as a 1% drop in mortgage rates. But… not so much in today’s volatile, unusual, and much more manipulated market.
What Are “Interest Rates?” Do They All Move In Unison?
Last year, I wrote a blog called What Are Interest Rates? Do They All Move In Unison?
In that blog, I discuss the differences between the (1) 10-Year Treasury Yields; (2) The Prime Rate; (3) The Fed Funds Rate; (4) Mortgage-Backed Security Yields; and (5) Average Mortgage Rates.
I also explain how there is no “one mortgage rate” that market-watchers follow and how all the rates do not always move in unison. I highly recommend revisiting that blog and/or sharing it with clients.
No “One Interest Rate” For Borrowers Too
As a quick aside, we often tell individual borrowers that there is “no one interest rate” for them as well.
This is because there are as many as twelve factors that impact an individual borrower’s rate, as I explain in this blog – 12 Factors That Impact A Borrower’s Rate (another blog I strongly suggest revisiting or sharing with clients).
Founder/Broker | JVM Lending
(855) 855-4491 | DRE# 1197176, NMLS# 310167 | <urn:uuid:8dd73439-c328-4f00-a55b-8dc943d4b08d> | CC-MAIN-2022-33 | https://www.jvmlending.com/blog/mortgage-rates-do-not-equal-10-year-treasury-rates/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.950393 | 553 | 2.078125 | 2 |
Delhiites breathed the cleanest air after almost a year with the Air Quality Index (AQI) settling at Satisfactory Level “83” on Friday as reported by an official of Central Pollution Control Board (CPCB). Monsoon hit Delhi last week and swept away the dust and pollution improving the air quality. The areas of NCR, such as Gurugram, Faridabad, Noida and Ghaziabad, also reported ‘satisfactory’ air quality.
Monsoon has arrived early this time in North India and knocked the doors of Delhi with light rain on Monday and Tuesday, followed by heavier showers on Wednesday and Thursday. The rains brought relief to Delhiites from searing heat as well as drastically dropped air quality.
There was a plunge in the air quality in mid-June because of massive sandstorms blowing from Rajasthan, Haryana and Punjab which resulted in AQI levels dropping beyond “severe.” This brought into the light that emergency level pollution has become a summer-problem too, and is not only restrained to winter smog.
The AQI has different levels depending on the values – 0-50 is considered ‘good’, 51-100 comes under ‘satisfactory’, 101-200 is deemed ‘moderate’, 201-300 is termed ‘poor’, 301-400 is ‘very poor’ and 401-500 falls in ‘severe’.
“The air quality is expected to further ameliorate on Saturday and in the coming days. The monsoon winds have cleaned the dusty air and brought the air quality to the satisfactory level,” said Gufran Beig, a scientist at the Air Quality and Weather Forecasting and Research Institute (SAFAR).
He further stated that the Delhi might witness the air quality touching level ‘good’ in the forthcoming days. | <urn:uuid:c4ad326d-23e1-4045-9f29-0798fda9a552> | CC-MAIN-2022-33 | https://www.aqi.in/blog/delhi-breathed-cleanest-air-after-a-year/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.942503 | 398 | 1.828125 | 2 |
A combination of glass-ionomer and composite resin, these fillings are a mixture of glass, an organic acid, and resin polymer that harden when light cured (the light activates a catalyst in the cement that causes it to cure in seconds). PEX-based materials do not contain Bisphenol A and are the least cytotoxic material available. firstname.lastname@example.org There are many challenges for the physical properties of the ideal dental restorative material. Other materials can be selected when restoring teeth where moisture control techniques are not effective. The gels used for micro-abrasion are composed of phosphoric acid. Some abrasive materials are used in the form of paste and others as Polishing Strips. Dental Implant Materials The vast majority of dental implants used today are made of pure titanium or a titanium alloy. Titanium Nanotechnology is aimed at the fabrication of nanoparticles, nanospheres, nanorods, nanotubes, nanofibers, dendrimers, and dendritic copolymers, each with unique properties which find applications on dental materials. Types of Restorative dental materials a) Direct restorative materials: Used intraorally. Compomers are essentially made up of filler, dimethacrylate monomer, difunctional resin, photo-activator and initiator, and hydrophilic monomers. In some circumstances, less tooth structure can be removed compared to preparation for other dental materials such as amalgam and many of the indirect methods of restoration. , Zinc oxide eugenol is usually used as a temporary filling/luting agent due to its low compressive strength and thus easily removed or as a lining for amalgam as it is incompatible with composites resins. , It is supplied as a two paste system. While you are surely well-familiar with the form of zirconia used be jewelers, the experts in dental labs use zirconium oxide combined with two types of metals, hafnium and yttrium, to produce dental implants. They are brittle and are not always recommended for molar fillings. Titanium dental implant materials - Made from metal, Titanium is regarded as the most common type of dental implant materials. Tin and amalgam were also popular due to lower cost, but were held in lower regard. Because of the vast aesthetic possibilities they offer, the ceramic restorations have become the material of choice in fixed prosthetics (Crowns and Bridges). For years, they have been considered the benchmark of restorative dental materials. ... Not valid for previous or ongoing work and cannot be combined with other discounts or dental discount programs. These fillings are sometimes sensitive to cold for a couple of weeks. For internal bleaching, for example a tooth having darkened after a root treatment, carbamide peroxide is also used. The Swedish government banned the use of mercury amalgam in June 2009. The metal used can be an alloy of base metals such as cobalt and Chromium, high Noble/ Noble metal alloy such as palladium, silver and gold. They are interim materials which may have therapeutic properties. Improvements in the beauty, strength, and durability of materials like porcelain and zirconium have made cosmetic restorations more natural and lifelike than some of the best materials in use just 10 or 15 years ago. There are many different types of dental products, and their characteristics vary according to their intended purpose. In USA, the U.S. Food and Drug Administration is the regulatory body for dental products. In 1969, Zirconium oxide was first used for medical purposes. Most people can tolerate titanium or an alloy well, without developing any sort of allergic reaction to the metal. Our chart makes it easy to compare dentures and helps you learn more today! In addition it is an electrical and thermal insulator while also releasing fluoride rendering it bacteriostatic, furthermore it being radio-opaque makes it an excellent lining material. Gold fillings are sometimes quite expensive; yet, they do last a very long time—which can mean gold restorations are less costly and painful in the long run. Generally, resin modified glass-ionomer cements can achieve a better aesthetic result than conventional glass ionomers, but not as good as pure composites. Handle. It is also radio-opaque allowing fillings to be visible by X-rays. Recent advances in dental porcelains and consumer focus on aesthetic results have caused demand for gold fillings to drop in favor of advanced composites and porcelain veneers and crowns. Bone filling with artificial bone grafts has made considerable progress and has largely replaced heterogeneous transplants (no longer used) and homogenous transplants (still occasionally used). This research and testing institution are accredited to perform several test procedures for dental products. Today this material is the first choice in conservative restorative dentistry, thanks to the important progress made for pulp protection and in the adhesive techniques. This material is used in removable prosthetics for framework and clasps. Impression Materials. Its mechanical properties and longevity has made it a first choice for many years. It is used in implantology due to its antiallergic qualities. Examples include: Dental cements are used most often to bond indirect restorations such as crowns to the natural tooth surface. Art portion working cast 4. It is used to make the artificial gingiva in removable dentures. Most dentists tell patients their dental crowns will last from 5 – 15 years, even though many remain functional significantly longer. Although they are tooth-colored, glass ionomers vary in translucency. The chemistry of the setting reaction for direct restorative materials is designed to be more biologically compatible. Ideally, filling materials should match the surrounding tooth structure in shade, translucency, and texture. New generations: The aim is tissue regeneration and use of biomaterial in the form of a powder or solution is to induce local tissue repair. However, one of the advantages of GI compared to other restorative materials is that they can be placed in cavities without any need for bonding agents (4). However eugenol may have an effect on resin based filling materials as it interferes with the polymerization and occasionally causes discoloration, thus caution should be taken when using both in tandem. Teeth can be filled with gold; porcelain; silver amalgam (which consists of mercury mixed with silver, tin, zinc, and copper); or tooth-colored, plastic and glass materials called composite resin fillings. , Polycarboxylate cement have decent compressive strength to resists amalgam condensation and are acidic but less acidic then phosphate cements due to it having a higher molecular weight and polyacrylic acid being a weaker acid than phosphoric acid. The primary reason of the addition of filler is to decrease the proportion of resin and increase the mechanical strength besides improving the material's appearance. Because indirect dental restorations are fabricated on these casts or die replicas, it is essential that the particular gypsum product be carefully manipulated to ensure an accurate restoration. Amalgam does not adhere to tooth structure without the aid of cements or use of techniques which lock in the filling, using the same principles as a dovetail joint. They come in a powder and liquid which are mixed on a pad or in compules which are for single usage and light cured with a LED light curing unit. Examples include: Dental impressions are negative imprints of teeth and oral soft tissues from which a positive representation can be cast. Steel (chrome-cobalt) Provisional Materials. Different types of impression materials are available. amalgam, composite resin, glass ionomer, temporary restorative materials,tooth whitening products, gold alloy, ceramic castings. Its drawback is that it is extremely hard and can sometimes fracture. Bis-GMA based resins contain Bisphenol A, a known endocrine disrupter chemical, and may contribute to the development of breast cancer. The cost is similar to composite resin. What types of dental instruments are more often referred to by number than by name? As with other composite materials, a dental composite typically consists of a resin -based oligomer matrix, such as a bisphenol A-glycidyl methacrylate (BISGMA), urethane dimethacrylate (UDMA) or semi-crystalline polyceram (PEX), … These two properties are essential because patients have varying soft-tissue undercuts (shallow or deep undercuts). A temporary dressing is a dental filling which is not intended to last in the long term. Its unaesthetic aspect is also a shortcoming. Bonding Agents. Lead fillings were used in the 18th century, but became unpopular in the 19th century because of their softness. There are many uses of Zirconium oxide, but today there are only three types of Zirconia, containing ceramic, used in dental applications: Yttrium cation-doped tetragonal zirconia polycrystals Magnesium cation-doped partially stabilized zirconia The bond of composite resin to tooth, is especially affected by moisture contamination and cleanliness of the prepared surface. Their aim is to prolong the vitality of the tooth when this seems possible (Calcium hydroxide). Indirect restorations are ones where the tooth or teeth to receive the restoration are first prepared, then a dental impression is taken and sent to a dental technician who fabricates the restoration according to the dentist's prescription. Most modern composite resins are light-cured photopolymers, meaning that they harden with light exposure. One survey of dental practices in the mid-19th century catalogued dental fillings found in the remains of seven Confederate soldiers from the U.S. Civil War; they were made of: Acrylics are used in the fabrication of dentures, artificial teeth, impression trays, maxillofacial / orthodontic appliances and temporary (provisional) restorations, however they can not be used as tooth filling materials because they can lead to pulpitis and periodontitis as they may generate heat and acids during (setting) curing, and in addition they shrink. 5 Main Types When you need a crown, you immediately start thinking about the types of dental crowns and cost. , GIs are usually used as a lining material for composite resins or as luting agents for orthodontic bands. They are biocompatible with the dental pulp to some extent. These are related to personal cavity risk and factors like grinding teeth (bruxism).. This is because today there are many different types of crowns that vary depending on materials, cost, procedures, and patients’ needs. , Fillings have a finite lifespan; composites appear to have a higher failure rate than amalgam over five to seven years. Still, they are generally considered good materials to use for root caries and for sealants. The bone grafts are made of a micro porous ceramic, which is biocompatible (Bio-Oss). In addition, GI is bacteriostatic due to its fluoride release from un-reacted glass cores. Impressions are used in the dental surgery to produce accurate (varying degrees of accuracy) negative reproductions of the patients’ teeth, surrounding tissues and dental arches. B. METAL PARTIAL DENTURES This denture has a metal base, usually made from an alloy containing cobalt and chrome. Setting takes place by a combination of both an acid based reaction and chemically activated polymerization, light cured versions contain a photo-initiator usually camphorquinone and an amide. Everyday masticatory forces and conditions must be withstood without material fatigue. Amalgam is still used extensively in many parts of the world because of its cost effectiveness, superior strength and longevity. The main reasons for failure are cavities that occur around the filling and fracture of the real tooth. Generally, composite fillings are used to fill a carious lesion involving highly visible areas (such as the central incisors or any other teeth that can be seen when smiling) or when conservation of tooth structure is a top priority. These include myriad neural defects, mainly caused by impaired neurotransmitter processing.. Dental restorative materials are used to replace tooth structure loss, usually due to dental caries (dental cavities), but also tooth wear and dental trauma. Unfortunately it has given poor results in implantology and cannot be recommended in this field. It is usually supplied as a power containing Zinc Oxide and a liquid containing aqueous Polyacrylic acid. Due to the known toxicity of the element mercury, there is some controversy about the use of amalgams. This helps to offset the blatant appearance of an all-gold crown. There is also a material that contains glass particles and is known as glass ionomer. • Silver—gives it strength • Tin—gives it workability and strength • Copper—gives it strength and low corrosion • Zinc—suppresses oxidation They are not subject to shrinkage and microleakage, as the bonding mechanism is an acid-base reaction and not a polymerization reaction. On other occasions, such materials may be used for cosmetic purposes to alter the appearance of an individual's teeth. According to American Civil War-era dental handbooks from the mid-19th century, since the early 19th century metallic fillings had been used, made of lead, gold, tin, platinum, silver, aluminum, or amalgam. The main types of crowns used in dentistry include: 1. Compomers have high staining susceptibility. Dental products are specially fabricated materials, designed for use in dentistry. Dental crowns and dental bridges are closely linked. Grey gold is usually chosen because it is less visible. The aesthetic fillings exist since a long time, but the recent development of composite resins (by 3M) made a great impact in dentistry. The _____ _____ is the portion of a dental instrument that is used on the tooth surface or for mixing dental materials. The Teeth. These are used to optimize the aesthetics of yellowed front teeth. Requisite physical properties include low thermal conductivity and expansion, resistance to different categories of forces and wear such as attrition and abrasion, and resistance to chemical erosion. Research has shown that, while amalgam use is controversial and may increase mercury levels in the human body, these levels are below safety threshold levels established by the WHO and the EPA. They also form a strong bond with dentine and enamel allowing it to form a coronal seal. Its great characteristic was discovered in 1950. The material is classified as ceramic and mimics closely the color and appearance of teeth. Zirconium is mainly used for the framework of fixed prosthetics. Crowns: Common Materials Used for Making Dental Crowns. Dental CAD/CAM Materials. A common use of temporary dressing occurs if root canal therapy is carried out over more than one appointment. It is usually cured by light. However, it has been demonstrated that the extremely low levels of bis-GMA released by composite restorations do not cause a significant increase in markers of renal injury, when compared to amalgam restorations. In an attempt to improve the mechanical properties of the conventional GI, resin-modified ionomers have been marketed. While the incorporation of silver achieved this, cermets have poorer aesthetics, appearing metallic rather than white. in dentistry, dental silver amalgam, resin composites, dental cements and bone replacement materials. Particular products and drugs are used for root treatments. Different dental clinics recommend different types of dental fillings.The types of dental fillings used are meant to prevent the tooth from further decay and breakage, and also to create a comfortable sensation as the patient chews food. In dentistry gold is found in the form of gold alloys. These crowns are very durable, but there are some drawbacks. Heat and byproducts generated cannot damage the tooth or patient, since the reaction needs to take place while in contact with the tooth during restoration. Titanium is an extremely strong and durable metal that provides excellent stability to implanted teeth. The ideal restorative material would be identical to natural tooth structure in strength, adherence, and appearance. Glass ionomer can be placed in cavities without any need for bonding agents . [medical citation needed], Gold fillings have excellent durability, wear well, and do not cause excessive wear to the opposing teeth, but they do conduct heat and cold, which can be irritating. Working End. However, due to its low compressive strength it is unable to withstand amalgam packing thus a strong cement base material should be placed above it to counter this. Dental Composite is a Synthetic Resin which has gained popularity as a restorative material as it is insoluble (saliva and other fluids), aesthetic, insensitive to dehydration, easy to manipulate and reasonably inexpensive. :91–92, Tooth colored dental composite materials are either used as direct filling or as construction material of an indirect inlay. You can see a comparison of Venus Diamond and Estelite Omega here . Elasticity- Elastic impression materials are used in patients with deep undercuts as it must be flexible enough to reach the end-point of the undercut. They can then be polished to achieve maximum aesthetic results. That is, there is no added risk of renal or endocrine injury in choosing composite restorations over amalgams. Cermets also have a similar compressive strength, flexural strength, and solubility as glass ionomer cements, some of the main limiting factors for both materials. The resorbable membranes used for guided osseous regeneration are now the choice of technique in oral surgery. Dental composite resin. It is not uncommon for a gold crown to last 30 years. Clinical studies have shown cermets perform poorly. Rigidity- Inelastic (rigid) impression materials are used with patients with shallow undercuts. There are many functions to dental lining materials, some of which are listed below: Calcium Hydroxide has a relatively low compressive strength and a viscous consistency making them difficult to apply to cavities in thick sections, a common technique used to overcome this issue would be to apply a thin sub-lining of a calcium hydroxide lining and then building up with zinc phosphate prior to amalgam condensation. These exhibit shrinkage in a dry environment at temperature higher than 50C, which is similar to the behavior of dentin. Due to its relatively weaker mechanical properties, Compomers are unfit for stress-bearing restorations but can be used in the deciduous dentition where lower loads are anticipated. The teeth of a denture are typically made from various types of resin or porcelain. :91–92 Porcelain materials can be strengthened by soaking fired material in molten salt to allow exchange of sodium and potassium ions on the surface as this successfully create compressive stresses on the outer layer, by controlling cooling after firing, and by the use of pure alumina inserts, a core of alumina or alumina powder, as they act as crack stoppers and are highly compatible to porcelain. The teeth of dentures are made of acrylic resin or ceramics. For dental fillings, see, Resin modified glass-ionomer cement (RMGIC), Evaluation and regulation of dental materials, CS1 maint: DOI inactive as of September 2020 (, "Recent advances in pulp capping materials: an overview", "Dental cavity liners for Class I and Class II resin-based composite restorations", "When and why you should use a liner/base", "Calcium hydroxide liners: a literature review", "Influence of radiopaque fillers on physicochemical properties of a model epoxy resin-based root canal sealer", WHO - Mercury in Health Care :Amalgam is a mixture of mercury and a metal alloy, "Sweden will ban the use of mercury on 1 juni 2009", "Genetic polymorphisms of catechol-O-methyltransferase modify the neurobehavioral effects of mercury in children", "A review of glass ionomer restorations in the primary dentition", "Retention loss of resin based fissure sealants - a valid predictor for clinical outcome? Commonly used as luting agents or as cavity base materials, however they tend to be rubbery during its setting reaction and adhere to stainless steel instruments thus most operators would prefer not to use them in deep cavities. Novel dental materials make their appearance in the market and often a dentist is confused about the right choice. For day use, derivatives of hydrogen peroxide are used. Note that root canaled (endodontically) treated teeth have AFR's between 2% and 12%. Academy of Dental Materials members click here to register for free access to Dental Materials online. After drilling the caries out of the tooth, the dentist applies a thin layer (approximately 1/2mm) to the base of the tooth, followed by light curing. Desirable Properties – Several properties are required of a material to be used for making casts, models, or dies. The cavity preparation of a glass ionomer filling is the same as a composite resin. Zinc oxide eugenol can be used as linings in deep cavities without causing harm to the pulp, due to its obtundant effect on the pulp as well as its bactericidal properties due to Zinc. They are used in prosthodontics (to make dentures), orthodontics, restorative dentistry, dental implantology and oral and maxillofacial surgery. These bioactive materials release chemical agents in the form of dissolved ions or growth factors such as bone morphogenic protein, which stimulates activate cells. However, it is very expensive due to the advanced technology it requires. Fixed dental restorations include two classes of prosthetic constructions: dental crowns and dental bridges.Their main characteristic is they are permanently fixed on natural teeth, posts or dental implants and do not have to be removed for cleaning.. (GICs do not undergo great dimensional changes in a moist environment in response to heat or cold and it appears heating results only in water movement within the structure of the material. It is mainly used for posterior reconstructions. a) Indirect restorative materials: Used extra orally. This was before lead poisoning was understood. Dental operators require materials that are easy to manipulate and shape, where the chemistry of any reactions that need to occur are predictable or controllable. Dental bridges can be fabricated in metal-ceramic combination or can be all porcelain or all metal. Teeth can be filled with gold; porcelain; silver amalgam (which consists of mercury mixed with silver, tin, zinc, and copper); or tooth-colored, plastic, and materials called composite resin fillings. Compomers themselves cannot adhere to the tooth tissue due to the presence of resin which can make it shrink on polymerisation. Porcelain fillings are hard, but can cause wear on opposing teeth. Specialty materials for Endodontics or Periodontics. Steel (chrome-cobalt) This material is used in removable prosthetics for framework and clasps. These are available in blocks for use with CAD-CAM systems. Formed indirectly over a cast or models. Its drawback is that it is extremely hard and can sometimes fracture. Equal length of 2 pastes are dispensed into a paper pad and mixed.. Today, several dental filling materials are available. However, there are certain subpopulations who, due to inherited genetic variabilities, exhibit sensitivity to mercury levels lower than these threshold levels. Generates a relatively high pH environment around area surrounding the cement due to calcium hydroxide leaking out thus making it bactericidal. Dental products are specially fabricated materials, designed for use in dentistry. This article is about types of dental restorative materials. The dental prosthesis or false teeth are medical treatments for people who are missing one or all of their teeth. Therefore, it’s important for you to differentiate the various types of tooth fillings and to understand what your options are when it comes to tooth fillings. Clinically, this material was initially used as a biomaterial to replace the lost osseous tissues in the human body. A Comparison of Dental Crown Materials Dentistry now offers more choices than ever before when it comes to restorative materials for teeth. fabricate restorations / prosthetic devices directly on the teeth or tissues. Crowns are used for restoring teeth that have been damaged or diseased, and essentially they protect and extend the functionality of your challenged teeth, or to cap implants. Uptake of oral fluid causes them to show staining soon after placement. Lining GI contains glass of smaller particle sizes in comparison to its adhesive restorative mix to allow formation of a thinner film. Anesthetics. These Dental Abrasive material particles coat the surface of the burs and act on the tooth or restorative materials by rotation of the bur using a hand piece. Whitening Materials. It is also used for permanent sealing of crowns and bridges as is very well tolerated. , It has the strongest compressive and tensile strength out of all the linings, thus it can withstand amalgam condensation in high stress bearing areas such as class II cavities. The goal of research and development in restorative materials is to develop the ideal restorative material. The purpose of this is to protect the dentinal tubules and the sensitive pulp, forming a barrier-like structure. This makes the tooth slightly more vulnerable to microleakage and recurrent decay. This is why its use has become very limited in todays dentistry. On mixing a chelate compounds are formed. Also commonly named “filling”, the amalgam is a sealant made of small particles of silver, tin and copper allied with mercury. The type of filling (restorative) material used has a minor effect on how long they last. All these disadvantages led to the decline in the use of this restorative material. Calcium silicate-based liners have become alternatives to calcium hydroxide and a preferred material among practitioners for its bioactive and sealing properties; the material triggers a biological response and results in formation of bonding with the tissue. , Nano-ceramic particles embedded in a resin matrix, are less brittle and therefore less likely to crack, or chip, than all-ceramic indirect fillings; they absorb the shock of chewing more like natural teeth, and more like resin or gold fillings, than do ceramic fillings; and at the same time more resistant to wear than all-resin indirect fillings. The portion of a dental instrument that the operator grasps is the _____. Compomers release fluoride at low level, so they cannot act as a fluoride reservoir. Like an acrylic partial, the material used for the gums is a pink acrylic and the replacement teeth are enamel-colored resin. :136–137. It is also radio-opaque and acts as a good thermal and electrical insulation. The concept of using "smart" materials in dentistry has attracted a lot of attention in recent years. The fillings do not wear as well as composite resin fillings. This is because composite resins bind to enamel (and dentin too, although not as well) via a micromechanical bond. , The reaction is an acid-base reaction between silicate glass powder and polyacrylic acid. •Type I : Impression material rarely used Non-elastic impression material • Type II Model of plaster used for 1.dignostic cast 2.articulation of stone cast 3. It holds up better than glass ionomer, but not as well as composite resin, and is not recommended for biting surfaces of adult teeth, or when control of moisture cannot be achieved.. There are many different types of dental products, and their characteristics vary according to their intended purpose. These fillings are a mixture of glass and an organic acid. This page was last edited on 19 October 2020, at 17:29. How well people keep their teeth clean and avoid cavities is probably a more important factor than the material chosen for the restoration.. Because of the vast aesthetic possibilities they offer, the ceramic restorations have become the material of choice in fixed prosthetics (Crowns and Bridges). Upon mixing of the material components, there is no light cure needed to harden the material once placed in the cavity preparation. Microleakage can be minimized or eliminated by utilizing proper handling techniques and appropriate material selection. Composite is also used to seal permanently crowns and bridges. Although glass ionomers can be used to achieve an aesthetic result, their aesthetic potential does not measure up to that provided by composite resins. , It is usually supplied as 2 pastes, a glycol salicylate and another paste containing Zinc Oxide with Calcium Hydroxide. Below are the common types of dental implant materials used in making dental implants today. Two major benefits of this type of denture are: Conventional glass ionomers are chemically set via an acid-base reaction. Conventional glass-ionomer (GI) cements have a large number of applications in dentistry. The MTA (Mineral Trioxide Aggregate) is a very biocompatible material that has been used successfully since several years, particularly in endodontics involving apical resection. Amalgam is a metallic filling material composed from a mixture of mercury (from 43% to 54%) and powdered alloy made mostly of silver, tin, zinc and copper, commonly called the amalgam alloy. Gold foil was the most popular and preferred filling material during the Civil War. If the vitality of the tooth cannot be preserved, the pulp chamber and the root canals will be disinfected and hermetically sealed. Technique, accuracy, taste, ease of manipulation, cost, dimensional stability a… After the initial set, glass ionomers still need time to fully set and harden. It can also be used in rare cases of metal allergy with removable prosthetics. The lower layers of the crown are gold, while the final layer is made with porcelain. This material is used for temporary fillings of deciduous teeth. Commonly used as pulp capping agents and lining materials for silicate and resin-based filling materials. A pellet was rolled slightly larger than the cavity, condensed into place with instruments, then shaped and polished in the patient's mouth. It also has a unique effect of initiating calcification and stimulating the formation of secondary dentine due to an irritation effect of the pulp tissues by the cement. Here are some of the categories of dental materials: Dental Composites. Some variations are also radiopaque which makes it good for X ray cavity detection. GICs are usually weak after setting and are not stable in water; however, they become stronger with the progression of reactions and become more resistant to moisture. This cavity lining is often used with a high strength base to provide strength, rigidity and thermal insulation. Composite resin fillings (also called white fillings) are a mixture of powdered glass and plastic resin, and can be made to resemble the appearance of the natural tooth. The composite is inserted into the cavity and hardened with a polymerisation lamp. Dental Materials publishes original research, review articles, and short communications. Top dental composite picks If you had to pick one and only one composite to have in your office, your best bet would be a hybrid like Venus Diamond . , Care has to be taken in handling such material as it has a strong bond with stainless steel instruments once it sets.. Its main flaw however is the fact that it contains mercury (admittedly in a stable form). Service Offering ( MD lists , AD HD , HP ), Why choose a dentist who is a member of the “AMDG”, Dentofacial imagery and radiation protection, Treatment abroad at very attractive prices. Although compomers have better mechanical and aesthetic properties than RMGIC, they have few disadvantages which limit their applications. Composite resins experience a very small amount of shrinkage upon curing, causing the material to pull away from the walls of the cavity preparation. The Nordic Institute of Dental Materials (NIOM) evaluates dental materials in the Nordic countries. :91–92 They are hard and rigid thus able to resist abrasion forces, are brittle due to surface irregularities, porosities, tendency to undergo static fatigue, and is good aesthetically as it mimics appearance of natural teeth due to various levels of shades. The latter was traditionally the preferred material because it was stronger and more durable, according to David L. Baker, DDS.Porcelain is still used in some instances and has a number of advantages: Some dental restorative materials such as acrylic monomers in resin-based materials and, Lining materials serve as an insulating layer to the tooth pulp from sudden changes in temperature when the patient, Additionally, lining materials are electrically insulating, preventing corrosion by, Alkaline nature promotes anti-bacterial atmosphere, Low thermal conductivity can provide thermal insulation, Soluble to oral fluids thus restricted to dentine coverage only, Viscous consistency making it difficult to apply to cavities in thick sections\, Low compressive strength need a second layer of strong cement base above it, Compatible with most restorative materials, Hard to handle due to strong bond with stainless steel instruments, Rubbery during setting reaction thus hard to manipulate in deep cavities, Can be used as a temporary filling or lining as it is easy to remove even after set, Lowest compressive and tensile strength of all linings only can be used on areas with small or non stress, Incompatible with resin composites due to polymerization interference, Very high compressive and tensile strength, Very adhesive to enamel and dentine thus don't need a bonding agent, Good compatibility with restorative materials. It is an ideal material because of its harmlessness, precision, and rigidity, which is essential for important prosthetic realisations. The filling was usually left "high", with final condensation—"tamping down"—occurring while the patient chewed food. Structure. The disinfectants will be active (for example corticoids) but the permanent seal of the canals will be done with an inert substance (for example gutta- percha). It is a type of CADCAM ceramic used in dentistry for the last 20 years, popular due to its biologic compatibility and its aesthetic properties. This ultimately limits the strength of the materials, since harder materials need more energy to manipulate. Another layer might be applied if the cavity is very large and deep. Flasking procedure for acrylic denture 43. In Europe, dental materials are classified as medical devices according to the Medical Devices Directive. [medical citation needed]. The most common types of bonded porcelain crowns are made with gold. There must also be good bonding strength to the tooth. Although cosmetically superior to amalgam fillings, composite resin fillings are usually more expensive. View a simple chart with the different types of dentures from Aspen Dental. Today, several dental filling materials are available. However, the metallic colour is not aesthetically pleasing and tooth coloured alternatives are continually emerging with increasingly comparable properties. Dental cermets, also known as silver cermets, were created to improve the wear resistance and hardness of glass ionomer cements (mentioned above) through the addition of silver. It has its own setting reaction. The most important disadvantage is lack of adequate strength and toughness. The majority of clinical studies indicate the annual failure rates (AFRs) are between 1% and 3% with tooth colored fillings on back teeth. GI is used as a lining material as it is very compatible with most restorative materials, insulates thermally and electrically and adheres to enamel and dentine. Dental crowns are a very popular choice for dental restorations. Here is a list of Abrasive materials … Dental crown, dental bridge. In order to obtain an accurate impression, a suitable property of impression material must be used. There are two categories of gold fillings, cast gold fillings (gold inlays and onlays) made with 14 or 18 kt gold, and gold foil made with pure 24 kt gold that is burnished layer by layer. Another combination of composite resin and glass ionomer technology, with focus lying towards the composite resin end of the spectrum. Glass ionomers are about as expensive as composite resin. Radiopacity in dental materials is an important property that allows for distinguishing restorations from teeth and surrounding structures, assessing the absorption of materials into bone structure, and detecting cement dissolution or other failures that could cause harm to the patient. With new developments, dentists and patients have a variety of ceramic materials to choose from to get a stronger, more reliable, and more aesthetically-pleasing crown than ever before. Direct restorations are ones which are placed directly into a cavity on a tooth, and shaped to fit. For night use, they consist of “carbamide peroxide” gels. ", "Longevity of posterior composite restorations: a systematic review and meta-analysis", https://www.youtube.com/watch?v=-keGMbCHC2A, https://en.wikipedia.org/w/index.php?title=Dental_material&oldid=984351445, CS1 maint: DOI inactive as of September 2020, Articles with unsourced statements from January 2018, Articles with unsourced statements from February 2020, Creative Commons Attribution-ShareAlike License. Dental Bridges Benefits Materials Used And Types What material is used for dental bridges? In between each visit, the pulp canal system must be protected from contamination from the oral cavity, and a temporary filling is placed in the access cavity. , Zinc oxide eugenol has the lowest compressive and tensile strength in relative to the rest of the liners thus this lining should be limited to small or non stress bearing areas such as Class V cavities. As a result, any bonding attempted will be disrupted at this stage. This material is used in ways similar to the use of composite resin fillings. By Dr. George Ghidrai. Impression materials are designed to be liquid or semi-solid when first mixed, then set hard in a few minutes, leaving imprints of oral structures. The reaction consists of an acid base reaction with Zinc oxide reacting with the acid groups in polyacid to form a reaction product of unreacted zinc oxide cores bound by a salt matrix with polyacrylic acid chains cross linking with zinc ions. Compomers are not adhesive, therefore they require bonding materials. These dentures are fitted into place using different strategies and materials. Common dental impression materials include: Historically these products were used as impression materials: Dental lining materials are used during restorations of large cavities, and are placed between the remaining tooth structure and the restoration material. As conservation of tooth structure is a key ingredient in tooth preservation, many dentists prefer placing materials like composite instead of amalgam fillings whenever possible. These particular individuals may experience adverse effects caused by amalgam restoration. Zirconia has several advantages over titanium. Lining materials protect the weak tooth from post-operative hypersensitivity, reducing patient discomfort and allowing the tooth to heal at a faster rate after the procedure. • Type III Dental stone used for making 1.full or partial denture model 2.orthodontic model 3. , Below is a summary of the advantages and disadvantages of dental cermets.. They can help you speak better and chew your food with ease along with giving you your smile back. Casts (positive reproductions) are created from dental impressions and are used to fabricate various dental prostheses. The properties of an ideal filling material can be divided into four categories: physical properties, biocompatibility, aesthetics and application. Light activated versions are also available which contains polymersation activators, hydroexyethyl methacrylate, dimethacrylate which when light activated will result in a light activated polymerization reaction of a modified methacrylate monomer. What Type of Dental Crown Should I Choose? The principal aim of Dental Materials is to promote rapid communication of scientific information between academia, industry, and the dental practitioner. Dental Material Dental materials include such items as resin composites, cements, glass ionomers, ceramics, noble and base metals, amalgam alloys, gypsum materials, casting investments, dental waxes, impression materials, denture base resins, and other materials used in restorative procedures. 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Fabiola Chavarria recently participated in and graduated from the HCT program in 2021. She is from the community of Troilo, one of two communities ViviendasLeón works in, in Nicaragua. She is currently producing vegetables, work that previously had been accessible only to men.
The inequality gaps and the difficult situation in which Fabiola Chavarria lived, a 28-year-old peasant woman motivated her and other women like her, to organize and participate in the training cycle of the HCT Human Capacity Training program, which ViviendasLeón provides in the communities of Sutiava. The program provides tools to improve their living conditions and better manage their lives, through the work they carry out in their humble communities.
Last year ten new families completed HCT, and today they join many other women who are protagonists of the Family Farming Program. They were taught technical skills in the workshop recently organized by our agricultural technician Camilo Melendez, called: "Importance of Small Family Farms, building sustainable livelihoods", whose objective was to provide knowledge and training in the use and good management of vegetable gardens, pest management, germination and farming innovation for a better quality and quantity of vegetables and fruits produced.
This activity was carried out in Camilo’s agro-ecological farm, located outside of León. This workshop is one of many planned activities for women like Fabiola who are studying to improve their technical knowledge of farming, and affirming the right of rural women to receive technical training and support to become farmers, improve their production of vegetables, the use of the land and small-scale diversified production systems, and improve the quality of crops while encouraging the marketing of the harvest produced.
During the course, a tour of the agro-ecological farm was carried out where the women were able to see examples of other low-cost project initiatives, including a Tilapia fish pond hatchery, a black Iguana hatchery, and a Dragon fruit plantation, and new production techniques for cucumber, chiltoma and tomato.
During the training these new farmers shared their experiences, anecdotes and reflections of the work they have been doing in their farms. They mentioned use of methods and techniques for pest control, preparation of seedlings, and types of crops they harvest.
Fabiola Chavarria commented:
“When I started to participate in the HCT training process, I was a very shy woman with self-esteem problems.” Today Fabiola Chavarria is experiencing some positive changes and has overcome many obstacles. As she says, "for example, in our country Nicaragua, women have had few opportunities to work in the fields." | <urn:uuid:dad889da-ff1f-480e-9698-8c1727a51743> | CC-MAIN-2022-33 | https://viviendasleon.org/updates/2022/rural-women-modernize-farming | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.968471 | 555 | 2.265625 | 2 |
Who Do You Think You Are?: Season 6 Episode 5Andrew Denton
Broadcaster Andrew Denton investigates his family history. A generation ago Andrew’s family anglicised their name from Ditkofsky to Denton, a decision taken to keep members safe at a time of entrenched racial intolerance. Andrew’s father, author Kit Denton, walked away from his Jewish ancestry when he married a Catholic woman and became a proud atheist. For these reasons Andrew’s knowledge of his Jewish roots until now has been scant. On the trail of his ancestors, Andrew’s journey takes him to London and Belarus. He is excited by the prospect of meeting descendants of his great grandfather who fathered twelve children. He finds none - instead the horrors of the Holocaust crash down on Denton as he investigates his family history, meeting with the last survivor of the Treblinka extermination camp, Samuel Willenberg, who has since passed away. | <urn:uuid:8b55e05c-7f17-49f4-bb2f-ee1c6b858b0a> | CC-MAIN-2022-33 | https://www.sbs.com.au/ondemand/video/288133699949/who-do-you-think-you-are-s6-ep5-andrew-denton | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.97373 | 193 | 1.78125 | 2 |
Would you trade your identity for a bag of marbles?
‘A Bag of Marbles’ adapts Joseph Joffo’s memoir and his escape from the Nazis
A Bag of Marbles
Directed by Christian Duguay
Adapted screenplay by Christian Duguay and Benoît Guichard
Based on the novel by Joseph Joffo
Starring Dorian Le Clech, Batyste Fleurial, Patrick Bruel, Elsa Zylberstein
Jewish brothers Joseph and Maurice and their family are on the run within a Nazi-occupied France. The film is based on Joseph Joffo’s powerful memoir about Joseph and Maurice’s separation from their family and their escape from the Nazis that hunt them down. Multiple times, the family is reunited, only to be forced to separate just after arriving; later, the brothers are captured by the Nazis, held at gunpoint, and slapped in the face for not admitting they are Jewish. “Are you Jewish?” The insistent answer: “No.”
Joseph and Maurice both go off on a journey. This is a cycle of escapades; the parents reveal that this was not the first time the family had to escape when we hear about the pogroms in Russia. The brothers’ journey is long, as it seems that over the next few years, the Nazis occupy more and more of France. Fewer people can be trusted. Yet we witness moments of kindness, the first from a lucky meeting with a priest who continues to help them, and an interesting one with a Jewish doctor working for the Nazis.
The narrative plays with irony of the need to deny one’s identity in order to save it, but the most powerful moment is its ending. Joseph ends up working for a bookstore owner who is an anti-Semite, but after France is freed, the townspeople revel in this freedom and begin to attack the bookstore owner and his family. Joseph, who was forced to deny his identity throughout the entire film, finally stands up and announces “I am Jewish!” to the terrified bookstore owner. Their eyes meet; he unknowingly had been protecting a Jewish boy the whole time — the one that he hated has now saved his life.
This is a story about trading one’s identity for survival. The symbolic gesture of trading your Jewish identity for survival comes early on as Joseph exchanges his yellow star for a bag of marbles that eventually is left behind. Each time the brothers leave a city marks a breaking of promises, a shred of dignity and innocence remains before them. What Joseph grips onto most tightly is the blue, beaten-up marble that is his. He clenches it tightly during his bout of meningitis. Survival is paramount, and, clenching onto the precious blue marble, Joseph holds out hope that there is a reason to keep living.
With less powerful or clever writing, the film could easily have felt too lengthy with the numerous long moments not directly involved with the Nazis, but this is a film about livelihoods, not just an escape. We move from a barber shop fashioning the appearance of others to a youth working facility where Joseph and Maurice fashion their identities as Algerian Catholics. They aren’t always running; sometimes the journey also involves selling cigarettes in Nice or playing in a field of grass.
The aesthetic language of the film reflects this: the lush background of France’s cities and greenery, coupled with the emotive orchestration, the French poeticism and meditative tone take over the film. Joseph, the precocious younger brother, lets us in on his thoughts of his developing philosophy on living and why he chooses to live. We watch him grow up from the “crybaby” (as his brother calls him) who lost his blue marble to one who refused to let go of his life. For, even in times of crisis, happiness can exist, and that is what they seek. | <urn:uuid:853c31df-7a1e-4269-bbc1-75dca6cc1362> | CC-MAIN-2022-33 | https://thetech.com/2018/04/19/a-bag-of-marbles-movie-review | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.971585 | 832 | 1.796875 | 2 |
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Integrated Vehicle Health Management: Essential Reading
- Progress In Technology
- ISBN 978-0-7680-8074-2
Published September 25, 2013 by SAE International in United States
- 240 pages
Integrated Vehicle Health Management (IVHM) is a relatively new subject, with its roots back in the space sector of the early 1990s. Although many of the papers written around that time did not refer to it as IVHM, the fundamental principles of considering an integrated end-to-end system to monitor the overall health of the asset were clearly visible. As the subject of Integrated Vehicle Health Management (IVHM) and its associated technologies have grown up, businesses are making the transformation from selling a product to selling a service. This can be viewed as a positive disruption, as a relatively small technology breakthrough is being brought to market for a large business benefit. The sequence “sense—acquire—transfer—analyze—act “ feeds the information (processed data) on the asset’s health into the Operations or Management control center. Here, decisions can be made on maintenance actions with knowledge of the supply chain status, MRO loading, etc., provided by Maintenance and Logistics systems. Undoubtedly, a much more efficient and economical modus operandi. This book brings together a collection of twenty –two SAE International Technical papers on this very theme, organized according to specific areas of interest: • Engines • Airframes • Electrical Power Systems • Supporting Systems • Architecture They were selected by Dr. Ian K. Jennions, Director of IVHM Center at Cranfield University, in the UK. Dr. Jennions was also the editor of three other books on Integrated Vehicle Health Management, published by SAE International: • IVHM: Perspectives on an Emerging Field • IVHM: Business Case Theory and Practice • IVHM: The Technology | <urn:uuid:58022b77-25b4-43c4-a79b-7798c308ee81> | CC-MAIN-2022-33 | https://saemobilus.sae.org/content/PT-162 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.944422 | 423 | 1.5625 | 2 |
Posted: February 16th, 2021
Your research paper may be written on one of the following topics:
I encourage you to ask yourself the following questions as you decide on a topic. Do I find this topic interesting? Although simple, this question is essential. Your personal interest about an issue or topic can and will make a big difference when you are researching and writing your paper. Is the topic personally or professionally rewarding? Will the research project answer questions about problems at work or provide you with a vehicle for professional advancement? Projects on work-related issues often result in visibility or frameworks for discussion with fellow professionals.
The paper should contain the following sections:
I. The Introduction
Describe why you chose this particular topic. Why do you think that it is an important issue in management responsibilities and practices?
II. The Review of the Literature
The Review of the Literature involves locating, reviewing, and evaluating resources that provide both background material and information on related studies. You must include a minimum of 8-10 sources in the review with the majority of sources being journals and periodicals rather than books. You may not use websites as sources in the review; however you will be using search engines, such as EBSCO, to locate appropriate sources. Amberton has many online sources which you can locate via the library tab on Amberton University’s website.
As you review your sources, look for the major subtopics of the material and organize your literature under these various subtopics. It is important to organize your literature review in the sequence best ordered for a logical flow of the information. An article-by-article presentation, stringing them together, is much less appealing than a review organized by subtopics.
All material paraphrased, summarized or directly quoted from another source must include documentation within the paragraph. Directly quoted material should also include quotation marks. Failure to properly document imposes severe grade penalty, as it is considered plagiarism. Most paragraphs in your review should contain a citation as you are reviewing what other researchers and authors are saying about your topic. When including your opinions or experiences within the review, make it clear that you are doing so. If you are unfamiliar with APA documentation, consider visiting the QEP tutorial located in your class portal or the following websites:
The concluding section of your paper should include your opinions and personal experiences about the issues raised. How will you use the information for personal or professional development? What advice would you give other professionals based on both your experiences and on the literature?
Your Reference List is an alphabetical listing of your sources by author’s last name. If the source does not list an author, I prefer that you cite by the title of the article and then list by title of the article alphabetically in the reference list. With articles downloaded from EBSCO as well as some other sources, you will have the original citation. Use that original citation both within the paper and in the reference list. With other search engines, you will not necessarily have the original volume, issue, or pages, although you will have the date and the journal in which the article appeared. In that case, the complete web address should appear in the reference citation. When checking the sources cited within your literature review, I should be able to match them exactly to the reference section of your paper. Check this before submitting the assignment.
This assignment is generally 10-12 pages in length and APA format is required. If you require information about how to cite using APA, please refer to: www.apastyle.org
Place an order in 3 easy steps. Takes less than 5 mins. | <urn:uuid:7847b316-29f9-40cb-8832-8a12843a410b> | CC-MAIN-2022-33 | https://professionalsessays.com/2021/02/16/management-responsibilities-practice-operations-management-homework-help/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.943755 | 755 | 2.375 | 2 |
HAMDEN -- — The blue-shirted sheriffs were a familiar sight, as was the "court in session" sign and, of course, the procession of black- robed justices.
But a table by the metal detector revealed that this was no ordinary meeting of the state Supreme Court. Splayed on the table, with tags newly attached, was an evidence room's worth of pen knives, pepper sprays, assorted eating utensils and other sharp or potentially dangerous items seized, temporarily, from spectators.
The crowd wasn't bent on revolution; the justices held court Tuesday in an auditorium at the Quinnipiac College School of Law, where students apparently are better armed than most visitors to the court's quarters in Hartford.
Five members of the court -- Chief Justice Ellen Ash Peters and Associate Justice David M. Borden were not on the panel -- were at the law school as part of an outreach program to bring the court's workings to law students. During the afternoon session, the justices heard arguments on whether military recruiters should be barred from the University of Connecticut Law School because the armed forces discriminate against homosexuals.
A group of students sued UConn, and 15 months ago a Superior Court judge issued a permanent injunction barring military recruitment at the school, saying the military's policy of excluding openly gay people violates Connecticut's 1991 Gay Rights Act. That law bars discrimination based on sexual orientation and explicitly prohibits the use of state facilities "in furtherance of any discrimination."
As hundreds of students watched, an assistant attorney general and a lawyer for the Connecticut Civil Liberties Union argued the matter to Associate Justices Joette Katz, Robert I. Berdon, Robert J. Callahan, Flemming L. Norcott Jr. and Richard N. Palmer. As is often the case at the Supreme Court, much of the lawyers' efforts were devoted to divining the intent of the legislature when it wrote several laws regarding the rights and obligations of campus recruiters.
Assistant Attorney General Paul M. Shapiro said military recruiters should be permitted at UConn under a 1984 law that requires state- run schools to provide the same on- campus recruiting opportunities to the military as are offered to nonmilitary recruiters.
But Berdon challenged Shapiro, asking whether a private employer that discriminated against gays would be treated any differently than the military. Shapiro acknowledged that the private company would be barred from recruiting, but said the military has never been subject to the same anti-discrimination rules as other employers. The military, for example, is not subject to all federal laws prohibiting discrimination on the basis of age, gender and physical disability. The military can deny a person with disabilities from taking part in combat, for instance.
Norcott asked Shapiro if he believed the legislature intended to promote anti-discrimination laws, but make an exception for the military, a position he said would be similar to saying that anti-discrimination is "almost" the public policy of the state.
"I didn't read Brown v. Board of Education to say `almost.' Maybe it did," Norcott said, referring to the landmark U.S. Supreme Court school-desegregation case.
Shapiro responded that the public policy of the state is reflected in all of the laws approved by the legislature. He noted that the Gay Rights Act specifically exempts the Reserve Officer Training Corps program, and said recruiting was not mentioned only because it was already given special protection by the 1984 law.
But CCLU attorney Philip Tegeler disagreed, saying recruiting is not mentioned in the Gay Rights Act because the legislature did not intend to exclude military recruiters from the law.
"They considered the military and they chose to exempt only ROTC," Tegeler said.
Tegeler said the court must interpret the military recruiting law and the anti-discrimination law in a way that the two statutes do not conflict. He said the only reasonable interpretation was that the legislature, in passing both laws, intended to prohibit all employers, including the military, from recruiting on college campuses if they discriminate against homosexuals. | <urn:uuid:07749516-7d13-412d-a86a-1519f0112b77> | CC-MAIN-2022-33 | https://www.courant.com/news/connecticut/hc-xpm-1995-10-25-9510250357-story.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.96425 | 824 | 1.617188 | 2 |
Teaching children about money and budgeting are some of the most difficult lessons for me to teach them. Not only are these topics extremely diverse and complex, but children are fairly impetuous creatures and want everything right away.
Seeing down the road into the future is also a very difficult concept for them to grasp, since their idea of the future is what is for dinner that night. Even with these obstacles in our way, as parents, there are still a few ways to make teaching them the concept of budgeting easier.
1. The Basics
As with every lesson we teach our children, starting with the basics is the best way to begin. Children’s brains process information differently than adults do. So, if we want anything to have long lasting power for them, the information needs to be more simplistic and broken down into smaller chunks.
Starting children out with a simple piggy bank (although it doesn’t have to be an actual pig!) is one of the easiest first steps to implement. Since children are very visual learners, this gives them something to physically see and touch to begin the teaching process. They can put every little bit of change they receive, or find, into it.
Some great first lessons to teach are:
- What each coin looks like
- How much each piece is worth
- How many of them it takes to make $1.00
Once they have that down, next on the list is to teach them how much things REALLY cost. This requires knowing what the tax rates are in your city and state so that you can teach them how to calculate the sales tax.
A good way to do this is to take them shopping with you and have them pick out something they want. This doesn’t mean you are planning to buy this item (let’s say a pink flamingo pool float, for arguments sake), but you want it for educational purposes.
Let’s say your child has $10.00 with them and sees that the pink flamingo pool float costs $9.99. Most children automatically assume they have enough money to buy the toy. But, they don’t understand about sales tax yet.
This is where you, in all of your infinite financial wisdom, come in!
The sales tax where we are is 7.25%. If we whip out a calculator and do the math with them in the store, they will quickly see that they cannot afford the flamingo pool float just yet. This is because that $9.99 price tag, really becomes $10.71 when we include tax. They still need another $.71 in order to get this pool float.
Now, if you happen to live in one of the few states that don’t have a sales tax (GO YOU!), then this lesson doesn’t apply as heavily. But, it should still be taught, in case they ever travel anywhere outside of your home base, which they probably will.
2. Saving Up
Once they understand how much they actually need to purchase the thing they want, then they need to learn how to save. Saving can be a very difficult thing for a lot of children, because they want everything RIGHT NOW.
Starting with smaller goals for saving can help keep them on track for their larger goals. I have found that the visual aspect of keeping physical money in a piggy bank helps them see just how far they have come. Having them take out all of their money once a week and count it, is another good way to assist them with seeing just how much further they have to go until their goal is reached.
This usually lights a fire under their butts to earn more money that week so they can finally buy the thing they have been eyeballing. Seeing and touching money is a great motivating factor for kids!Seeing and touching money is a great motivating factor for kids! Click To Tweet
Once they have this basic saving skill grasped, then it’s a good idea to move on to teaching them how to budget for even bigger things. Some of these bigger things could be a car, college, a 2-year trek around the world, retirement, etc. These are not small items and they usually come with much larger price tags than that pink flamingo pool float we were using as an example. This is the point where the piggy bank is no longer the best method for saving.
In order to save for these bigger items, they need to move their money to a high yield savings account. The rates vary, but they will be able to save more, faster, simply due to the magic of compounding.
Here is a great example of how compounding works with $100.00. If this is all they have to put in and the high yield savings rate is 2.4%, then at the end of one year they will have $102.43 in that account. This may not sound like much, but they just made an extra $2.43 without doing anything. Imagine what they could do if they invested this money in something like Stockpile instead and got the average 7% rate of return!
3. Working for the Money
Now that they are really motivated to earn more money, getting them to work for it is the next step. Getting children to do chores around the house can be a difficult task sometimes, depending upon the child. But, when they have the motivating factor of a thing they want, they have a tendency to be much more excited to do chores.
I like to give the children a list of ALL the things that need to be done, both inside and outside the house. Then they each write down the chores they would prefer to do and how much they think each job is worth. Now, this is the interesting, and fun, part! What I, as the adult, and what they, as the children, think the chores are worth are usually very different numbers.
So we usually end up in a little bit of negotiation to come to a more realistic number. This is not only teaching children about working for money, but also just how much things are worth in today’s economy. So I wouldn’t suggest paying your children much more, if anything, than what the current market rate is for certain basic chores.
But learning the art of negotiation, and what they think their time is worth, are important life lessons.
Overall, teaching children to budget can be as easy or as difficult as you make it. But giving them the building blocks now can help ensure their long term financial literacy, and hopefully, success. To do so, keep these skills in mind:
- Teach them the basics regarding what money is and how much it is worth (Plus sales tax)
- Learning how to save is crucial (Plus compounding magic)
- Teach them how to earn money (Plus the art of negotiation)
Once they have these down, you can move on to more complicated financial lessons.
What are some ways you have successfully taught your children about budgeting and money? | <urn:uuid:30f2c698-84de-422b-b570-978ee65fd896> | CC-MAIN-2022-33 | https://everythingfinanceblog.com/26284/teach-your-children-about-budgeting.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.975607 | 1,454 | 3.28125 | 3 |
Lobster Diver Survives Being Swallowed and Spat Out by Whale20 June, 2022
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An experienced lobster diver survived being caught in a humpback whale’s mouth near Provincetown, Massachusetts on Friday morning.
Michael Packard was searching for lobsters on the ocean floor on his second dive of the day, approximately 45 feet below the surface, when he said he felt a bump and then he was in total darkness.
“All of a sudden, I felt this huge shove, and the next thing I knew it was completely black,” Mr Packard told WBZ-TV, following his release from the Cape Cod Hospital.
At first the 45-year-old thought that he was in the mouth of a great white shark, which are common in the area. But when he realised that he hadn’t suffered any obvious wounds from sharp teeth, he determined that he was in the mouth of a whale.
“I realised – oh my God, I’m in a whale’s mouth and he’s trying to swallow me.”
“And I thought to myself OK, this is it, I’m gonna die”.
Mr Packard said that his thoughts then went to his wife and sons, whom he feared he would never see again.
He estimates that he was in the whale’s mouth for 30 to 40 seconds. Mr Packard was able to continue to breathe, as he had his regulator in his mouth, but could feel the whale “squeezing with the muscles in his mouth” the whole time.
Mr Packard told CBSN Boston: “It was happening so fast, my only thought was how to get out of that mouth, and I realized, there was no overcoming of a beast of that size. He was going to do with me what he wanted to do.”
Luckily, fate was on Mr Packard’s side. He said he could tell that the whale didn’t like having him in its mouth.
“All of a sudden he went up to the surface. He just erupted and started shaking his head, and I just got thrown in the air and landed in the water and I was free.”
He added: “I just floated there. I couldn’t believe I got out of that.”
Josiah Mayo, a crewman from Mr Packard’s boat, saw the whale burst to the surface and spit out Mr Packard. Mr Mayo retrieved Mr Packard from the water before calling the shore by radio, and speedily returning to the Provincetown Pier.
An ambulance met Mr Packard at the pier and took him to Cape Cod Hospital; he was released Friday afternoon, having sustained some bruising and soft tissue damage to his legs whilst in the whale’s mouth.
Jooke Robbins, the director of Humpback Whale Studies at the Centre for Coastal Studies in Provincetown told The Cape Cod Times that what happened to Mr Packard was most likely an accident, caused by a somewhat clumsy, juvenile whale.
She said that as humpback whales feed, their mouths open and billow out in a parachute-like manner, obstructing their vision, which is likely what led to Mr Packard becoming trapped in the whale’s mouth. She added that humpback whales are not known to be aggressive, especially towards humans.
Incidents of humpback whales injuring swimmers and divers are exceedingly rare, if not nonexistent, Ms Robbins said. Adding: “It is not something I have heard happening before”.
Source: The Independent
Share with a friend | <urn:uuid:83241b75-c7e2-4433-9391-7df107a88ba4> | CC-MAIN-2022-33 | https://dearborn.org/preview/lobster-diver-survives-being-swallowed-and-spat-out-by-whale-8324 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.98713 | 770 | 1.632813 | 2 |
The interface allows for surface loading and geometries to be drawn in three dimensions. The output looks nice with contours of settlement and 3-dimensional views of increased stress in a given layer, and plots of settlement over time.
A couple of early notes based on their product data sheet and other online information:
- The layout of the problem may be in 3D as are the computation of increase in stress at depth due to surface loads. But the but the calculation of displacements and porewater pressures is performed in one dimension.
- Stress distribution can be calculated based on Boussinesq theory or 2:1 method.
- The materials can be modeled as linearly elastic, nonlinearly elastic, Janbu, or with time-dependent (consolidation) properties.
- Accounts for primary consolidation and secondary compression
- Can model wick drains to speed up consolidation settlement
- Ability to evaluate staged construction and groundwater conditions
Visit Rockscience’s website for more info and documentation. | <urn:uuid:bef6c97f-4f02-4d68-a83a-12dfdb712bd9> | CC-MAIN-2022-33 | https://geoprac.net/2007/09/rockscience-releases-settle3d-software/?shared=email&msg=fail | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.910578 | 207 | 2.78125 | 3 |
Yesterday we heard the tragic news of the passing of one our favourite characters, actors and what felt like a family member to some. My father and I had just sat down and ordered a nice meal to end a good day when we saw the news. We were both shocked and quiet for a while but then simultaneously raised our glasses and toasted. We toasted to a beautiful trilogy, beautiful memories at starwars celebration past July and to countless amazing moments we experienced with Carrie Fisher.
At a young age Carrie quickly became a household name as she took on the role of Princess Leia in the original Star Wars Trilogy. She was one of the first strong female characters presented to young girls at the time. I cannot imagine completely what that must have been like but I can speak of the impact she and her portrayal of Leia made on me at a young age. Growing up with both the originals and prequels I had both Princess Leia and Padme to look up to. Both were strong female figures with political ideologies and a strong sense of purpose that was already cemented in them before we meet them both in A New Hope and The Phantom Menace. Princess Leia stood for what was right, just and honourable. She alongside other strong female figures throughout my life showed me it was important and right to stand up for what you believe in, to stand up for others and to want to make a difference no matter how small or big.
For me however Carrie Fisher continued to be a source of inspiration after the release of the films. She has always been very open to us fans about everything going on in her personal life. As I am sure we are all aware it hasn’t always been the easiest path for her and she has made mistakes in the past. However she was always so open and upfront about them and shared them with us. She spoke out about mental health and attempted to break the bad stigma that surrounds the topic. She seemed to always also embrace that part of her and did not try to hide it from the whole word. The way the whole Star Wars family took her in and were all so accepting is a big reason as to why I am so proud to be part of it. We are a big open community and I truly believe we always made Carrie feel accepted not for who we wanted her to be but for who she was.
I have struggled with mental problems myself and so to see someone be so open about it definitely helped me open up with my family and friends about my own problems. This is one of the best things I could have done, and I also have her alongside others to thank for it. She also showed me it was not something to have to be embarrassed about or something I had to kill within me. I started to learn to accept myself for who I am and that that also included my quirkiness and some of my ticks. She showed to many that not everything is perfect and that it shouldn’t be. We all loved her for being imperfect and through this I think we helped her accept herself the way she helped us accept ourselves.
Past July I had the amazing experience of going to Star Wars Celebration 2016 in London. Both Carrie and Mark Hamill were present alongside many others. Knowing now that I was part of the last Celebration with Carrie definitely makes the experience even more magical. It was great to see the support she had from all the fans and how much she always gave back during all her interviews. It seemed she was one of the few genuine ‘celebrities’. She spoke her mind and whatever would come to it which sometimes got her into trouble but really just made us love her more. She was witty, smart and warm hearted.
Of course I can only speak of how I perceived her through interviews and I did not know her personally, but she always seemed genuine.
It is a true loss for her family, friends and the Star Wars community. She will be dearly missed and never forgotten. I look forward to seeing her appear on our screens one last time in episode 8 (maybe also in 9). We will then sadly have to say goodbye to Princess Leia however we can always find her in the Original Trilogy, The Force Awakens and inside our hearts.
Carrie Fisher 21/10/1956 – 27/12/2016 | <urn:uuid:1ac5c11f-f627-4428-8c32-d287fbe610d1> | CC-MAIN-2022-33 | https://clonecorridor.com/2016/12/28/carrie-fisher-a-princess-story/?like_comment=3814&_wpnonce=6cbbae8f29 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.991379 | 871 | 1.59375 | 2 |
What Are The Benefits Of Using Our Services?
Best Apps for College Students to Train the Brain
Training your brain for success is a process and not a one-time deal. It is a day-to-day progress that you can learn through different techniques and brain-stimulating activities. Engaging your brain to function more, develops its ability to adapt, change, and to work to your advantage especially for a college student.tutors umbrella com reviews
Eating the right food is not your only ticket to a healthy brain. Keeping the brain healthy requires techniques that will help sharpen your thinking skills. Improve your processing speed and reaction time, be better in planning and decision making, while improving your memory with brain games and brain training apps.
Best Brain Training Apps for College Students
What are the highly-recommend apps that can help train your brain, and at the same time improve your grades in the university? We have selected the best ones according to college students.
CogniFit Brain Fitnessget someone to do your homework
Improving your cognitive skills is essential to boost memory and to improve your capability to learn and solve problems. As a student, you will be faced with plenty of ideas to learn and problems to resolve, academically, and in life, to get through college. The CogniFit Brain Fitness App is a great tool that can be used to enhance your concentration through different games designed and developed by neuroscientists.
The app features a progress tracker that can give you insights about the overall health of your brain. You can play alone or challenge your friends and family via the competitive player feature of the app. Before trying out the games, the app will require you to take a simple quiz that will determine the level of difficulty suitable for your profile. Spend at least 20 minutes twice or thrice a week playing the app to see a gradual improvement in your thinking skills.
Free subscription comes with four games while the full version is available at $13 a month of $120 annually. It is currently available via iOS.
Luminosity is one of the most popular brain-stimulating apps available in both Android and iOS. It is another application dedicated to improving your brain’s cognitive skills. The app features games that are focused in developing the five areas of cognitive education; problem-solving, speed, flexibility, attention, and memory. Games are played against the clock and change from time to time so users get to enjoy new challenges even with frequent use.
Developers of the games suggest using the game at least once a day to improve your mental skills and to track your progress and performance, compared to other users. It is customizable and can be adjusted according to your personal goals. Creating custom experiences is also possible in the app, allowing you to be more proficient in cognitive skills that you want to focus on. You can replay your daily mind work out or proceed to the next recommended brain game as you please.
The free version has limited access but is already good enough to start with. You can upgrade to enjoy the full version for $15 a month or $80 a year.
Brain Fitness Pro
If you are looking to improve your memory or increase your focus, the Brain Fitness Pro mobile application is recommended for you. The app features memory training exercises that enhance your focus while improving your problem-solving skills. Your memory is also developed and trained as you go over the games and activities featured in the app.
The developers of the game believe that intensive brain workouts can generally improve the cognitive skills of a person that is very beneficial as you age. Intensive memory training keeps the brain working in top shape and it can be very helpful in the long run. Several enjoyable mini-games are featured in the area such as Memory, Reflexes, Dynamic Vision, Addition, Pattern Memory, and Color Judge that were developed specifically to engage the brain to function to keep it healthy and working on its best level.
The app is available for free but with limited access. The full version is available for less than $5 a month both in Android and iOS.
Brain stimulating games and applications are beneficial in keeping the brains sharp, even with age. They are proven to help in keeping memory skills in top shape, even as we age. At best, brain games and apps can improve your performance. The more you practice and enhance a specific cognitive skill, the better you will be in that area. As you level up and improve your scores, you’ll feel smarter and more confident too. Brain games are also a productive way to kill time and to entertain yourself in between class lectures and school activities. So yes, it’s definitely something you should try for yourself.
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Real Customer Reviews | <urn:uuid:7be8f5a7-e324-4948-a69c-a860666ae6ca> | CC-MAIN-2022-33 | https://paysomeonetodo.com/best-apps-for-college-students-to-train-the-brain | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.95778 | 976 | 2.125 | 2 |
Jennifer is a writer from Ohio. She was diagnosed with a BRCA 1 mutation, and hopes sharing her experiences will help other women.
Understanding BRCA Mutations
What Are BRCA Mutations?
BRCA mutation are, quite simply, mutations of the BRCA genes. The BRCA1 and BRCA2 genes are tumor-suppressor genes. When working correctly, these genes repair DNA damage that could lead to cancers, including breast and ovarian cancer in women. Everyone has these genes. When there is a deleterious (harmful) mutation present, these genes can’t do their job, and you are left with a significantly increased risk of breast cancer and ovarian cancer throughout their lives, as the mutation prevents the body from fixing damaged DNA and suppressing tumors like it should. Basically, I am just like the X-Men, but my mutant power is the exact opposite of healing factor.
How Are BRCA Mutations Inherited?
BRCA mutations can be inherited from either parent. The BRCA1 gene is located on chromosome 17 and the BRCA2 gene is located on chromosome 13 (i.e. they have nothing to do with the sex chromosomes. If a medical professional tries to tell you that only your mother’s side of the family matters with regard to BRCA mutations or breast cancer risk, they probably shouldn’t be in the medical field. This is basic biology). If one parent has a BRCA mutation, each child (daughters or sons) has a 50% chance of also having the same mutation.
How to Get Tested
If you have a strong family history of breast cancer and/or ovarian cancer, or if one of your close relatives has a documented BRCA mutation, you can make an appointment with your primary care doctor to get a referral to a genetic counselor. The genetic counselor will then go over your family history with you and put in an order for the appropriate blood test if it is recommended for you.
I Have a Mutation, What Now?
After you get your BRCA test results back, you will be referred to a doctor that specializes in BRCA positive patients. Make your appointment for a consultation and exam. At this appointment, your doctor will discuss surveillance and possible preventative options with you. They will likely recommend that you have breast cancer screenings every six months. The exact recommendations your doctor makes for you may depend on the exact mutation you have, as well as your current age, whether you have already had cancer, and possibly other health factors.
I am supposed to have an MRI and mammogram alternating every six months (so one of each per year). Your doctor may also suggest you consider risk-reducing surgeries, including prophylactic mastectomy and prophylactic salpingo-oophorectomy (removal of fallopian tubes and ovaries). Some women choose to have surgery to virtually eliminate the risk of cancer, but this is an extremely personal decision. Many women choose to stick with regular screenings, rather than the preventative surgeries. I am sticking to surveillance and will discuss the oophorectomy with my doctor when I am closer to the appropriate age to consider that surgery (35-40). I will not be choosing the preventative mastectomy option.
The most important thing to do upon finding out you have a deleterious BRCA mutation is to keep up on regular screenings. Your chance of beating breast cancer is much, much higher if it is caught in the earliest stages. For high risk women, including those with BRCA 1 or BRCA 2 mutations, your doctor will likely recommend regular breast MRIs and mammograms (depending on your age). Unfortunately, there aren’t yet any reliable ways to screen for ovarian cancer.
You will likely be instructed to start having an annual breast MRI earlier than mammograms. MRI can detect tumors in dense breast tissue more accurately than mammogram, so it is better for younger women. It also doesn’t use any radiation, unlike mammograms. A contrast dye is injected into your arm during this test. The machine is loud, and you have to stay super still, but it’s not the most unpleasant medical test you will every have to go through.
Mammography is better at detecting microcalcifications than MRI, so you will also need to have regular mammograms as well. For women with BRCA mutations, you will likely need to start having mammographs at age 30, about 10 years earlier than average-risk women.
Ovarian Cancer Screening
There isn’t a reliable method of screening for ovarian cancer. There is a blood test that can be used to screen for it, called the CA-125 blood test, but my doctor said that it doesn’t detect it early enough for the test to work (I may seek a second opinion on this). Currently, the best option for preventing ovarian cancer is apparently risk-reducing surgery. (I did see some information on an ultrasound to screen for ovarian cancer while researching this article. I will ask my doctor about that at my next appointment).
Some women choose to have a prophylactic mastectomy upon learning that they are BRCA mutation positive. This means that your breast tissue is surgically removed to nearly eliminate the risk of developing breast cancer in the future. If your insurance allows you to have this surgery, they are also required to cover reconstruction procedures until you are completely satisfied with the results. Some women choose to forgo reconstruction after having the surgery as well. Discuss prophylactic mastectomy with your doctor to decide if it is right for you if you are BRCA positive.
Several years ago, BRCA 1 and 2 mutations were in the news headlines when Angelina Jolie found out that she had a BRCA1 mutation, and then decided to undergo a preventative mastectomy with reconstruction. Since this happened, many more women have been rushing to their doctors demanding to be tested for BRCA mutations, and those who tested positive may feel pressured to make the same medical choices as Angelina Jolie. Don’t feel like you have to make certain choices just because a celebrity did. What was right for a mega-rich celebrity might not necessarily be right for you, a regular person.
Read More From Patientslounge
I have decided against going this route for prevention. For me personally, I feel like surveillance is a better option. In some online communities for BRCA positive women, there does seem to be a lot of pressure to do the preventative surgery, but it isn’t the right choice for everyone.
BRCA positive women are encouraged to consider having their fallopian tubes and ovaries removed upon completion of childbearing, or around ages 35-40. This is a much more important preventative surgery, as there are no reliable ways to detect ovarian cancer early enough right now.
There are considerable side effects to this, so you be sure to discuss it with your doctor before making any decisions. It will cause you to experience menopause symptoms much earlier than you naturally would if you decide to undergo this option to prevent ovarian cancer.
Reproductive Intervention Options
If a woman with a BRCA mutation does want to have children, childbearing must be completed prior to having an oophroectomy. There may be options to have eggs frozen for later use, however. (Whether having children naturally when you know there is a 50% chance of them having a BRCA mutation is another ethical quandary entirely.)
If you do want to have children after learning of your BRCA mutation, it is possible to do invitro-fertilization, and have the resulting embryos screened for the mutation before implantation. Only the embryos that are free from the genetic defect will be implanted, assuring you that your children won’t have your BRCA mutation.
If you have a BRCA mutation and wish to have children in the future, ask your doctor for more information about these options. I’m personally not interested in becoming pregnant and had already made that decision before discovering my BRCA mutation.
If you find out that you have BRCA mutation after you have already had children, you should make sure to educate your children about BRCA mutations and encourage them to get tested for it after they turn 18.
- FORCE: Facing Our Risk of Cancer Empowered
FORCE is the only national nonprofit organization devoted to hereditary breast and ovarian cancer. Our mission includes support, education, advocacy, awareness, and research.
- Bright Pink | Breast and Ovarian Health Organization
Bright Pink is the only national non-profit focused on the prevention and early detection of breast and ovarian cancer in young women.
- Sharsheret - A Jewish Breast Cancer Organization
Sharsheret is a Jewish breast cancer organization that helps women and their families face breast cancer. Click here to learn more about our non-profit.
There is Hope
Learning that you have a BRCA mutation is a terrifying experience. As scary as knowing that you have a high risk of developing cancer can be, it is much better to know so that you can take steps to catch it at earlier stages or potentially prevent it. It is important to work with your doctor to determine the best course of action for managing your breast and ovarian cancer risk if you have a BRCA 1 or BRCA 2 mutation. There are also a number of organizations and online resources that can help you to navigate all of the medical decisions you will be faced with and to connect with other women facing the same thing.
This content is accurate and true to the best of the author’s knowledge and does not substitute for diagnosis, prognosis, treatment, prescription, and/or dietary advice from a licensed health professional. Drugs, supplements, and natural remedies may have dangerous side effects. If pregnant or nursing, consult with a qualified provider on an individual basis. Seek immediate help if you are experiencing a medical emergency.
© 2019 Jennifer Wilber
Kathy Burton from Florida on February 05, 2019:
Very informative and thought provoking article. Thanks for researching and sharing. Wish you all the best
Pamela Oglesby from Sunny Florida on February 04, 2019:
This is excellent informaton about the BRAC genes. I am more concerned about ovarian cancer for people as I think you can detect a lump in your breast more easily. I wrote an article about ovarian cancer after a friend of mine died from this disease, and the symtoms are not as easily recognized. Thanks for the excellent information. | <urn:uuid:16dcafc6-2e06-46d1-931f-cab3738cac8f> | CC-MAIN-2022-33 | https://patientslounge.com/conditions/I-Have-a-BRCA-Mutation-Whats-Next | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.955391 | 2,244 | 2.578125 | 3 |
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Why reagent grade enzymes for analytical chemistry?
SELECTIVITY Enzymes are able to find their substrate in complex mixtures
SPECIFICITY Enzymes only react with their substrate in the presence of other compounds
SENSITIVITY Enzymes find even the tiniest amount of their substrate in a scarce sample
SAFETY Enzymes react in gentle conditions, are non-toxic, and environmentally benign
WHAT ARE REAGENT GRADE ENZYMES? HOW DO THEY WORK? Learn More | <urn:uuid:cf14c6e2-5950-4cd9-b492-1b335796c9a6> | CC-MAIN-2022-33 | https://nitrate.com/analytical-enzyme-applications/agriculture | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571246.56/warc/CC-MAIN-20220811073058-20220811103058-00272.warc.gz | en | 0.896554 | 520 | 1.8125 | 2 |
As the digital economy is booming, a lot of changes will take place in our society in the near future.
We all have a crucial decision to make about what role we want to have in this future.
There are two kinds of people in the digital world; Consumers and Producers.
Consumers will only use the Internet and digital services to consume stuff. They watch Netflix, porn, memes, cat videos, and so on…
Producers are the few people who look for an opportunity to gain knowledge, start businesses, and build multiple streams of income.
The majority of people will only ever be Consumers and be fed by all the things that the Producers create. They will become a digital underclass.
Producers, on the other hand, are the ones who will truly understand the potential in the digital world and use it to create wealth and prosperity.
I’ve made my choice on what type of person I want to be, it’s time for you to make the same!
Check out this exclusive new webinar where my mentor Stuart shows the same strategies that he taught me and that I used to build up my online business with, something that made me a Producer.
Have a great day! | <urn:uuid:9bc471af-033b-49c8-8cb9-2f0a60988a6e> | CC-MAIN-2022-33 | https://ultimatelifesource.com/hologram-shorts/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.937775 | 254 | 1.585938 | 2 |
What should we pay attention to when buying a trackless train?
The trackless train is a kind of sightseeing train that gets rid of the restriction of the track. This advantage makes it more useful, and it is easier to adapt to various complex site environments, so it is very popular in the market. So what should users pay attention to when buying trackless trains?
1. Venue requirements
Why should we consider venue needs first? Before purchasing, it is necessary to fully investigate the current situation of the site, the flow of people, road conditions and other basic conditions, and then plan the driving route. The driving route must choose a road with good conditions, suitable slopes and no potential safety hazards.
2. Product positioning
According to the site survey of Article 1, we select the required products. If the road is wide and the flow is large, we should choose a large or medium-sized trackless train for a large number of passengers, otherwise, choose a small-sized train. If the slope is large, a fuel-type trackless train with independent brakes is a good choice.
3. Product quality
The safety of product quality has many aspects, such as production safety, material safety, structural safety of amusement equipment, safety of amusement equipment maintenance, safety of amusement equipment service life and other aspects. The safety of children’s amusement equipment is the primary condition for purchasing amusement equipment. Purchasing an amusement equipment with hidden safety hazards will not only cause the equipment to stop working, but also affect the normal operation of the amusement park. The important issue is the personal safety of tourists. If a safety accident is caused by the insecurity of children’s amusement equipment, the consequences are even more unimaginable. Therefore, the safety of children’s amusement equipment is the top priority. | <urn:uuid:2b1acb10-6998-407e-967b-0d9a1f0885ed> | CC-MAIN-2022-33 | https://www.jskidsrides.com/news/dinis-blog/what-should-we-pay-attention-to-when-buying-a-trackless-train | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.938227 | 369 | 1.6875 | 2 |
APP1: -BRING MUSIC TO YOU: Music/Video App using Flutter framework.
Task1: Flutter App Dovelopment
- create flutter app.
- Use function to make it more creative(Use assets *audios and *videos).
- It will play the music and videos using these kind of assets.
- Its has also the facility to play the music through the internet using Network function.
- We have use button for the music player features.
Flutter — a simple and high-performance framework based on Dart language, provides high performance by rendering the UI directly in the operating system’s canvas rather than through native framework.
Flutter also offers many ready to use widgets (UI) to create a modern application. These widgets are optimized for mobile environment and designing the application using widgets is as simple as designing HTML.
Now I will show, steps for creating the app:
The flutter SDK doesn’t have the support for playing audio I searched for the packages in pub.dev (package website for flutter). I found “Assests” package for playing local or network audios.
Step 1: update the pubspec.yaml file with required dependencies. PLEASE CHECK THE FOLLOWING IMAGE:
Step 2: There is a file in lib folder main.dart which will be the entry point of the app. For enabling the hot reload functionality in flutter I have used the Stateless widget.
Step 3: Return type of the main.dart file will be material app.
Now for the music player.
I have build the music player that runs the music locally and from the network in the same screen. You can use Tab Functionality that comes with flutter.
For using the asset package first make the assets folder in the directory where the project is saved(like assets folder below the android folder on the left side).
Then after creating the folder, update in the pubspec.yaml file that you are going to use the audio or video from this folder.
In order to play the audio locally we have to make ab object of AssetsAudioPlayer() class.
Then using different functions of AssetsAudioPlayer() class and associating them with different RaisedButtons we can create the different music player buttons for play, pause, stop.
Now for playing the music online AssetsAudioPlayer() class has audio.Network(‘url’) function defining.
Thankyou for your interest . | <urn:uuid:e47b6530-c94d-49db-ad84-e07dd509f8ce> | CC-MAIN-2022-33 | https://himanshusilswal.medium.com/bring-music-to-you-music-video-app-using-flutter-framework-a85af477697d?source=post_internal_links---------0---------------------------- | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.880707 | 518 | 2.171875 | 2 |
Usually the ideal keeps going are the ones where exactly we do not unhinge ourselves with the help of beats and even audiobooks or perhaps podcasts. Let’s face it, you will find functions if I truly get pleasure from a relaxing schedule including a excellent podcast nevertheless I dislike becoming including I might depend on earphones that will run. As well as clothing they’re not safe to with in the best place. Although how does one complete made the effort without them? Properly, start together with your brain. It’s rather an appealing concept. Frequently by myself mental performance is way more entertaining when compared with virtually any playlist or simply podcast. And then joining your downline may be too. There are truly basically no recommendations here. However , Consider the good offer you 6 ways you can stay kept amused relating to every run.
Squeak, drone, and just all-around never like everyday life for the entire to begin with 2-3 miles. Look at That i said that had been not hard. Just simply kidding. Jogging is hard the best very few cientos just before we in our groove. As a result solely set off in it as well as tell your own self simply how much you will draw being ball carrier, an individual, as well as in your everyday living for general. You shouldn’t position something back. Bring about is without a doubt that when you entirely push your body nuts by way of roman mile 3, everyone wide open your mind in place for quite a few great very creative electricity to get started sweeping all over stat mi 4. Plus you should tell the truth – everyone believes most things quite extremely creative not to mention enjoyable exists due to getting thoroughly nuts. Quite possibly jogging itself, correct?
State hello there for you to each of the existing along with non-living things you pass. Go searching you. There are tons from tiny insects working with you may possibly in no way realize while you’re playing music. Any of them are usually not so very little both, so maybe usually do not declare hello there in their mind away loud. Furthermore nevertheless in the year in addition to summer season you will likely view loads of “during the past living” wildlife (I’m hesitating upon expressing gone pertaining to fear of harmful anyone.) Just like, anyone know: “Hello possum, When i consider which you are at the time surviving yet again you have been not any longer, I believe gloomy meant for you. Just what a circle. A cir of life.” And in which case you feel the disappointment in addition to run-cry with regard to 15 seconds. I once were end where exactly Used to a new 15-second cry out for almost every once-alive puppy I exceeded roadside. Call your current emotions. That must be running’s all about.
Face up anybody you’re resentful with. You happen to be altogether only plus have occasion to deal with hence now could be enjoyable to help you “tell” another person you’ll be angry within precisely how you feel and how i feel. Certainly, you may have to produce each of their typical reactions to boot of which years up definitely exposing the way YOU experience the truth and also the reasons why have not nevertheless experienced it. You are individuals tell you “walking is without a doubt my treatment method?” Very well, this is real treatment method you can apply with the help of your family while you’re running. It truly does work, strive it.
Which means that naturally, if you can uncover your head and also accessibility your mad, comical, awesomeness throughout your family you should have a blast performing with no headsets! | <urn:uuid:6aaf2924-45ab-4c9e-aebf-b6bae90c8865> | CC-MAIN-2022-33 | https://www.jamboobanqueteria.com.br/2019/08/8-procedures-to-assist-you-to-continue-to-be/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00272.warc.gz | en | 0.96154 | 766 | 1.539063 | 2 |
Changes in gene expression suggest possible therapies to prevent and treat COVID-19 based on dexamethasone, calcitriol (vitamin D) and tocopherol (vitamin E) that disrupt the inflammatory “vicious circle” in COVID-19
Amsterdam NL – The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs). Yet it leads to widely diverse clinical symptoms, suggesting multiple pathogenic mechanisms. Writing in Restorative Neurology and Neuroscience, investigators describe how excessive activation of AhRs via the IDO1-kynurenine-AhR signaling pathway, which is used by many pathogens to establish infection, leads to “Systemic AhR Activation Syndrome” (SAAS). The authors also hypothesize that therapies targeting downregulation of AhRs and IDO1 genes should decrease severity of infection.
SAAS underlies inflammation, thromboembolism, and fibrosis that may lead to severe disease and death from COVID-19. When corona virus (CoV) infection persists, it activates IDO1 by massively releasing cytokines. This in turn perpetuates the already extensive viral activation of AhRs, and the self-limiting control mechanisms of the host immune response may derail, triggering the cytokine storm underlying the most severe symptoms of COVID-19.
“The SARS-CoV-19 virus is a living example of viral simplicity complicated by extreme target complexity,” explains lead author Waldemar A. Turski, MD, PhD, Department of Experimental and Clinical Pharmacology, Medical University in Lublin, Poland. “Direct activation of AhRs by CoVs may lead to diverse sets of phenotypic disease pictures, depending on time after infection, overall state of health, hormonal balance, age, gender, comorbidities, but also diet and environmental factors modulating AhRs.”
The authors demonstrate that CoVs are perfect viruses leaving nothing to chance and show how difficult it is to stop them after cell invasion. They describe how many of the features and symptoms of COVID-19 may be dependent on AhR activation, including thromboembolism, fibrosis, multiple organ injury, and brain damage. They also explore how environmental factors, such as urban dust and diesel fumes, may activate AhRs and make humans more prone to pathogens, including CoV. However, physical exercise plays a positive role in IDO1 function and downregulates AhRs.
The investigators hypothesize that when AhRs remain activated and clinical symptoms are mild, eliminating factors known to increase AhR activation or implementing factors known to suppress AhR activation should decrease the severity of infection. When the disease is fully established and symptoms are severe, IDO1 is believed to be continuously activated in addition to the CoV activation of AhRs. “Such a vicious cycle can only be efficiently interrupted by simultaneous downregulation of both AhR and IDO1. There is currently, however, no licensed medication specifically and simultaneously downregulating the activity of both AhR and IDO1,” notes co-author Les Turski, MD, PhD, German Center for Neurodegenerative Diseases, Bonn, Germany.
Co-author Artur Wnorowski, PhD, Department of Biopharmacy, Faculty of Pharmacy, Medical University in Lublin, Poland, undertook an intriguing challenge that yielded surprising results. “I analyzed major databases to identify chemicals that downregulate both AhR and IDO1, or AhR gene expression. I selected 596 molecules and an in-depth analysis of 23,526 experiments involving these molecules identified either a single molecule that repeatedly reduced AhR and IDO1 or AhR gene expression in human cells.”
The molecules were dexamethasone for AhR and IDO1, and calcitriol, the active form of vitamin D, which is also known to inhibit the spread of other viral infections, for the AhR gene. Likewise, tocopherol, a form of Vitamin E, might downregulate IDO1 and is known to play a positive role in response to viral infections and inflammation in aging. The authors call for epidemiological studies and prospective trials to determine if calcitriol and tocopherol supplementation should be recommended for the prevention of SARS-CoV-2 infections.
AhR activation in CoV-infected cells. CoV activate AhR by means of AhR-activating ligand independent of IDO1. Upon activation AhR translocates to the nucleus to bind to genomic DNA and to generate downstream effectors such as AhRR, CYPs, TiPARP, and cytokines. IDO1 is induced by inflammatory factors, such as TNFα and interleukins 6 (IL-6) and 1β (IL-1β). AhR also enhances its own activity through activation of IDO1-AhR-IDO1 positive feedback loop prolonging the effects of AhR activation by other pathways. Activation of IDO1 in immune cells leads to release of kynurenine, a tryptophan metabolite, which is an endogenous ligand activating AhR. Exogenous ligands binding to AhR are dioxins such as TCDD.
“Our concept is based on 40 years of research experience with the metabolism of tryptophan. Activation of IDO1 in immune cells leads to release of kynurenine, a tryptophan metabolite, activates AhR. IDO1 was the clue that brought us to the AhR-IDO1 axis concept and exposed the role that AhR may play in the pathogenesis of COVID-19,” says Dr. Waldemar Turski.
The Editor-in-Chief of Restorative Neurology and Neuroscience, Professor Bernhard Sabel from the University of Magdeburg, Germany, in recognition of novelty of the authors’ vision says: “The turning point defined by the authors’ concepts requires critical review of our habits, our relationships with the environment, and our education and research in the context of AhR modulation. We seem to be at the very beginning of novel discovery pathways and only see the very tip of an iceberg of unknown size that may critically affect our future.”
Because the authors are reporting on changes in gene expression only, their hypotheses need to be tested before claiming that there are benefits of any therapy in modulating the SARs-CoV-2 infection. Randomized controlled trials and large observational studies are needed.
Full text of the article is also available to credentialed journalists upon request. Contact Diana Murray at (+1 718-640-5678 or firstname.lastname@example.org). Journalists wishing to reach the authors should contact Sabine Hoffmann, Head of Communications and Press Spokeswoman of the German Center for Neurodegenerative Diseases in Bonn, Germany (+49 228 43302-260 or email@example.com).
About Restorative Neurology and Neuroscience
An interdisciplinary journal under the editorial leadership of Bernhard Sabel, PhD, Restorative Neurology and Neuroscience (RNN) publishes papers relating the plasticity and response of the nervous system to accidental or experimental injuries and their interventions, transplantation, neurodegenerative disorders and experimental strategies to improve regeneration or functional recovery and rehabilitation. Experimental and clinical research papers adopting fresh conceptual approaches are encouraged. The overriding criteria for publication are novelty, significant experimental or clinical relevance and interest to a multidisciplinary audience. iospress.com/journal/restorative-neurology-and-neuroscience
RNN Editorial Office
Prof. Dr. Bernhard Sabel
Institut für Medizinische Psychologie
Otto-v.-Guericke Universität Magdeburg
Tel: +49 391 672 1800
About IOS Press
IOS Press is headquartered in Amsterdam with satellite offices in the USA, Germany, India and China and serves the information needs of scientific and medical communities worldwide. IOS Press now publishes more than 80 international peer-reviewed journals and about 75 book titles each year on subjects ranging from computer science, artificial intelligence, and engineering to medicine, neuroscience, and cancer research. iospress.com | <urn:uuid:a5af4769-e05e-456a-9223-8f1a6ac415d2> | CC-MAIN-2022-33 | https://www.iospress.com/news/how-upregulation-of-a-single-gene-by-sars-cov-2-can-result-in-a-cytokine-storm | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570871.10/warc/CC-MAIN-20220808183040-20220808213040-00272.warc.gz | en | 0.899462 | 1,774 | 2.78125 | 3 |
Elisa Satjukow (Leipzig): Contested Heritage. The war in Kosovo and the NATO intervention in 1999
It’s war in Europe again, and while we watch the events in Ukraine, another European war is largely forgotten. Thirty years ago, the breakup of the former Yugoslavia began.
Bloody conflicts in Bosnia, Croatia and Kosovo not only claimed countless lives, they also drove hundreds of thousands of people to flee. In the face of the Srebrenica massacre and the scale of violence against civilians, NATO decided to intervene in the Bosnian war in 1995. Just four years later a new military intervention by NATO should bring an end to the violence in the Kosovo war. To this day, the transatlantic allies 78-day military campaign, which violated international law, is considered controversial. While the bombing often appears in European discussions about EU and NATO accession of the Western Balkan states only as a historical footnote of the Kosovo conflict, the situation in Kosovo and Serbia is quite different. Here, the commemoration of the events of 1998/1999 – albeit focusing on quite different aspects in each case – occupies a central place in national cultures of remembrance. The Albanian population of Kosovo remembers the military intervention primarily as support for the struggle for national independence. In Serbia, on the other hand, the event stands for an illegal attack on a sovereign state; the Kosovo war and the NATO intervention are largely treated as disparate events. In her lecture, Elisa Satjukow uses the example of the NATO bombing of Serbia and Kosovo in 1999 to illuminate the ambivalences of military interventions from the perspective of the people affected by the war. Using the example of the culture of remembrance – especially in the form of memorial days and monuments – she sheds light on the controversial legacy of this almost forgotten war in Europe.
Dr. Elisa Satjukow is a research assistant at the Department of East and Southeast European History. Previously, she was a fellow in the PhD program “Trajectories of Change” of the ZEIT-Stiftung and in 2019 she published her PhD thesis “The Other Side of Intervention. A Serbian Experiential History of the 1999 NATO Bombing” (transcript 2020). She studied Eastern and Southeastern European history, general and comparative literature, and Russian studies in Leipzig, Belgrade, and Volograd. In addition to her academic work, she was project manager at the Kompetenzzentrum Mittel- und Osteuropa in Leipzig and coordinator of the International MitOst Festival. Her focus is on the intertwined history of Eastern and Southeastern Europe from the 19th to the 21st century, especially everyday life, gender, transformation and knowledge history, memory cultures, postcolonial studies as well as theories and methods of historical studies.
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