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MED-1722 | Insulin-like growth factor-1 and childhood cancer risk | Overexpression of growth factors and/or their receptors is a common event in malignancy and provides the underlying mechanisms for one of the hallmarks of cancer, uncontrolled proliferation. Mounting evidence suggests that IGF-1 is involved in the pathogenesis and progression of different types of human cancer such as ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22870112"
} |
MED-1723 | The associations of diet with serum insulin-like growth factor I and its main binding proteins in 292 women meat-eaters, vegetarians, and vegans. | The lower rates of some cancers in Asian countries than in Western countries may be partly because of diet, although the mechanisms are unknown. The aim of this cross-sectional study was to determine whether a plant-based (vegan) diet is associated with a lower circulating level of insulin-like growth factor I (IGF-I) ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/12433724"
} |
MED-1724 | A low-fat, whole-food vegan diet, as well as other strategies that down-regulate IGF-I activity, may slow the human aging process. | A considerable amount of evidence is consistent with the proposition that systemic IGF-I activity acts as pacesetter in the aging process. A reduction in IGF-I activity is the common characteristic of rodents whose maximal lifespan has been increased by a wide range of genetic or dietary measures, including caloric res... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/12699704"
} |
MED-1725 | Integrative assessment of multiple pesticides as risk factors for non-Hodgkin's lymphoma among men | Methods: During the 1980s, the National Cancer Institute conducted three case-control studies of NHL in the midwestern United States. These pooled data were used to examine pesticide exposures in farming as risk factors for NHL in men. The large sample size (n = 3417) allowed analysis of 47 pesticides simultaneously, c... | {
"url": "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1740618/"
} |
MED-1726 | Major Pesticides Are More Toxic to Human Cells Than Their Declared Active Principles | Pesticides are used throughout the world as mixtures called formulations. They contain adjuvants, which are often kept confidential and are called inerts by the manufacturing companies, plus a declared active principle, which is usually tested alone. We tested the toxicity of 9 pesticides, comparing active principles a... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24719846"
} |
MED-1728 | Epidemiologic studies of glyphosate and cancer: a review. | The United States Environmental Protection Agency and other regulatory agencies around the world have registered glyphosate as a broad-spectrum herbicide for use on multiple food and non-food use crops. Glyphosate is widely considered by regulatory authorities and scientific bodies to have no carcinogenic potential, ba... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22683395"
} |
MED-1729 | Birth defects, season of conception, and sex of children born to pesticide applicators living in the Red River Valley of Minnesota, USA. | We previously demonstrated that the frequency of birth defects among children of residents of the Red River Valley (RRV), Minnesota, USA, was significantly higher than in other major agricultural regions of the state during the years 1989-1991, with children born to male pesticide applicators having the highest risk. T... | {
"url": "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241196/"
} |
MED-1730 | Epidemiologic studies of glyphosate and non-cancer health outcomes: a review. | The United States (US) Environmental Protection Agency (EPA) and other regulatory agencies around the world have registered glyphosate as a broad-spectrum herbicide for use on multiple food and non-food use crops. To examine potential health risks in humans, we searched and reviewed the literature to evaluate whether e... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21798302"
} |
MED-1731 | Glyphosate herbicide formulation: a potentially lethal ingestion. | Glyphosate surfactant herbicide (GlySH) toxicity is an uncommon poisoning. We report two fatalities involving suicidal ingestion of this herbicide. Both deaths occurred despite early recognition of the serious nature of the poisoning and aggressive treatment. The deaths in this series are analysed in the context of a r... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/15228468"
} |
MED-1732 | Glyphosate induces human breast cancer cells growth via estrogen receptors. | Glyphosate is an active ingredient of the most widely used herbicide and it is believed to be less toxic than other pesticides. However, several recent studies showed its potential adverse health effects to humans as it may be an endocrine disruptor. This study focuses on the effects of pure glyphosate on estrogen rece... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23756170"
} |
MED-1733 | Rhabdomyolysis from an intramuscular injection of glyphosate-surfactant herbicide. | INTRODUCTION: Glyphosate-surfactant herbicide (GlySH) is widely used as a non-selective herbicide. Most intoxicated cases are from ingestion, inhalation, and skin exposure. Intramuscular injection of GlySH has never been reported. We present a case of GlySH intoxication via intramuscular injection. CASE REPORT: A 42-ye... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/18787996"
} |
MED-1736 | Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology. | Glyphosate is a herbicide widely used to kill weeds both in agricultural and non-agricultural landscapes. Its reproductive toxicity is related to the inhibition of a StAR protein and an aromatase enzyme, which causes an in vitro reduction in testosterone and estradiol synthesis. Studies in vivo about this herbicide eff... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/20012598"
} |
MED-1737 | Time- and dose-dependent effects of roundup on human embryonic and placental cells. | Roundup is the major herbicide used worldwide, in particular on genetically modified plants that have been designed to tolerate it. We have tested the toxicity and endocrine disruption potential of Roundup (Bioforce on human embryonic 293 and placental-derived JEG3 cells, but also on normal human placenta and equine te... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/17486286"
} |
MED-1738 | Developmental and reproductive outcomes in humans and animals after glyphosate exposure: a critical analysis. | Glyphosate is the active ingredient of several widely used herbicide formulations. Glyphosate targets the shikimate metabolic pathway, which is found in plants but not in animals. Despite the relative safety of glyphosate, various adverse developmental and reproductive problems have been alleged as a result of exposure... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22202229"
} |
MED-1739 | Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells. | Glyphosate is the primary active constituent of the commercial pesticide Roundup. The present results show that acute Roundup exposure at low doses (36 ppm, 0.036 g/L) for 30 min induces oxidative stress and activates multiple stress-response pathways leading to Sertoli cell death in prepubertal rat testis. The pestici... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23820267"
} |
MED-1740 | Pesticide Roundup provokes cell division dysfunction at the level of CDK1/cyclin B activation. | To assess human health risk from environmental chemicals, we have studied the effect on cell cycle regulation of the widely used glyphosate-containing pesticide Roundup. As a model system we have used sea urchin embryonic first divisions following fertilization, which are appropriate for the study of universal cell cyc... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/11896679"
} |
MED-1741 | Differential Effects of Glyphosate and Roundup on Human Placental Cells and Aromatase | Roundup is a glyphosate-based herbicide used worldwide, including on most genetically modified plants that have been designed to tolerate it. Its residues may thus enter the food chain, and glyphosate is found as a contaminant in rivers. Some agricultural workers using glyphosate have pregnancy problems, but its mechan... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/15929894"
} |
MED-1743 | Compositional differences in soybeans on the market: glyphosate accumulates in Roundup Ready GM soybeans. | This article describes the nutrient and elemental composition, including residues of herbicides and pesticides, of 31 soybean batches from Iowa, USA. The soy samples were grouped into three different categories: (i) genetically modified, glyphosate-tolerant soy (GM-soy); (ii) unmodified soy cultivated using a conventio... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24491722"
} |
MED-1744 | Property rights and genetic engineering: developing nations at risk. | Eighty percent of (commercial) genetically engineered seeds (GES) are designed only to resist herbicides. Letting farmers use more chemicals, they cut labor costs. But developing nations say GES cause food shortages, unemployment, resistant weeds, and extinction of native cultivars when "volunteers" drift nearby. While... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/15727008"
} |
MED-1745 | Chemical composition of glyphosate-tolerant soybean 40-3-2 grown in Europe remains equivalent with that of conventional soybean (Glycine max L.). | The composition of glyphosate-tolerant (Roundup Ready) soybean 40-3-2 was compared with that of conventional soybean grown in Romania in 2005 as part of a comparative safety assessment program. Samples were collected from replicated field trials, and compositional analyses were performed to measure proximates (moisture... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/17608426"
} |
MED-1746 | The impact of altered herbicide residues in transgenic herbicide-resistant crops on standard setting for herbicide residues. | The global area covered with transgenic (genetically modified) crops has rapidly increased since their introduction in the mid-1990s. Most of these crops have been rendered herbicide resistant, for which it can be envisaged that the modification has an impact on the profile and level of herbicide residues within these ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21898904"
} |
MED-1747 | Is there a legacy of the U.S. Public Health Syphilis Study at Tuskegee in HIV/AIDS-related beliefs among heterosexual African-Americans and Latinos? | Knowledge of the US Public Health Syphilis Study at Tuskegee is sometime cited as a principal reason for the relatively low participation rates seen among racial/ethnic minorities, particularly African Americans, in biomedical research. However, only a few studies have actually explored this possibility. We use data fr... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23308036"
} |
MED-1748 | Complete Genes May Pass from Food to Human Blood | Our bloodstream is considered to be an environment well separated from the outside world and the digestive tract. According to the standard paradigm large macromolecules consumed with food cannot pass directly to the circulatory system. During digestion proteins and DNA are thought to be degraded into small constituent... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23936105"
} |
MED-1749 | Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada. | Pesticides associated to genetically modified foods (PAGMF), are engineered to tolerate herbicides such as glyphosate (GLYP) and gluphosinate (GLUF) or insecticides such as the bacterial toxin bacillus thuringiensis (Bt). The aim of this study was to evaluate the correlation between maternal and fetal exposure, and to ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21338670"
} |
MED-1750 | Clinical, Agricultural, and Evolutionary Biology of Myostatin: A Comparative Review | The discovery of myostatin and our introduction to the “Mighty Mouse” over a decade ago spurred both basic and applied research and impacted popular culture as well. The myostatin-null genotype produces “double muscling” in mice and livestock and was recently described in a child. The field’s rapid growth is by no mean... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/18591260"
} |
MED-1751 | Commercial conspiracy theories: a pilot study | There are many ways to categorise conspiracy theories. In the present study, we examined individual and demographic predictors of beliefs in commercial conspiracy theories among a British sample of over 300 women and men. Results showed many people were cynical and sceptical with regard to advertising tricks, as well a... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23818886"
} |
MED-1752 | Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. | The transforming growth factor-beta (TGF-beta) superfamily encompasses a large group of growth and differentiation factors playing important roles in regulating embryonic development and in maintaining tissue homeostasis in adult animals. Using degenerate polymerase chain reaction, we have identified a new murine TGF-b... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/9139826"
} |
MED-1753 | The current state of GMO governance: are we ready for GM animals? | Given the history of GMO conflict and debate, the GM animal future is dependent on the response of the regulatory landscape and its associated range of interest groups at national, regional and international levels. Focusing on the EU and the USA, this article examines the likely form of that multi-level response, the ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22361646"
} |
MED-1754 | Recursive Fury: Conspiracist Ideation in the Blogosphere in Response to Research on Conspiracist Ideation | Conspiracist ideation has been repeatedly implicated in the rejection of scientific propositions, although empirical evidence to date has been sparse. A recent study involving visitors to climate blogs found that conspiracist ideation was associated with the rejection of climate science and the rejection of other scien... | {
"url": "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600613/#!po=1.16279"
} |
MED-1755 | Occurrence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus in Turkey and Broiler Barns and Contamination of Air and Soil Surfaces in Their Vicinity | The emission of microorganisms, especially resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA), from poultry farms is of public interest, and its occurrence and relevance are controversially discussed. So far, there are limited data on this issue. In this study, we investigated the occurrence ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23417001"
} |
MED-1757 | Longitudinal Study of the Contamination of Air and of Soil Surfaces in the Vicinity of Pig Barns by Livestock-Associated Methicillin-Resistant Staphylococcus aureus | During 1 year, samples were taken on 4 days, one sample in each season, from pigs, the floor, and the air inside pig barns and from the ambient air and soil at different distances outside six commercial livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA)-positive pig barns in the north and east o... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22685139"
} |
MED-1759 | Livestock-associated methicillin-resistant Staphylococcus aureus responsible for human colonization and infection in an area of Italy with high density of pig farming | Background Livestock-Associated MRSA (LA-MRSA) belonging to ST398 lineage, common among pigs and other animals, emerged in Central and Northern Europe, becoming a new risk factor for MRSA among farm workers. Strains belonging to ST398 can be responsible for human colonization and infection, mainly in areas with high li... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23731504"
} |
MED-1760 | Effects of fast food branding on young children's taste preferences. | OBJECTIVE: To examine the effects of cumulative, real-world marketing and brand exposures on young children by testing the influence of branding from a heavily marketed source on taste preferences. DESIGN: Experimental study. Children tasted 5 pairs of identical foods and beverages in packaging from McDonald's and matc... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/17679662"
} |
MED-1761 | Marketing fast food: impact of fast food restaurants in children's hospitals. | OBJECTIVES: The objectives of this study were (1) to determine fast food restaurant prevalence in hospitals with pediatric residencies and (2) to evaluate how hospital environment affects purchase and perception of fast food. METHODS: We first surveyed pediatric residency programs regarding fast food restaurants in the... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/17142511"
} |
MED-1762 | Meat intake and reproductive parameters among young men | Background In the United States, anabolic sex steroids are administered to cattle for growth promotion. There is concern regarding the reproductive consequences of this practice for men who eat beef. We investigated whether meat consumption was associated with semen quality parameters and reproductive hormone levels in... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24681577"
} |
MED-1763 | The sensitivity of the child to sex steroids: possible impact of exogenous estrogens. | The current trends of increasing incidences of testis, breast and prostate cancers are poorly understood, although it is assumed that sex hormones play a role. Disrupted sex hormone action is also believed to be involved in the increased occurrence of genital abnormalities among newborn boys and precocious puberty in g... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/16672247"
} |
MED-1764 | Lipid Concentrations and Semen Quality: The LIFE Study | The decline in sperm count rates over the last 50 years appears to parallel the rising prevalence of obesity. As lipids levels are strongly associated with obesity, high lipids levels or hyperlipidemia may thus play an important role in the decline in fertility in addition to other environmental or lifestyle factors. T... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24596332"
} |
MED-1765 | Effects of simvastatin and pravastatin on gonadal function in male hypercholesterolemic patients. | Inhibition of cholesterol biosynthesis by hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase inhibitors could, in theory, adversely affect male gonadal function because cholesterol is a precursor of steroid hormones. The objective of this randomized double-blind trial was to compare the effects of simvastatin, prava... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/10647074"
} |
MED-1766 | Lipids and testicular function. | We studied 19 male patients with primary hyperlipoproteinaemia, a control group of 28 healthy men and 44 infertile males before any treatment was undertaken. Spermiogram, seminal biochemical studies, measurements of plasma hormone levels and lipid determinations were carried out. Most hyperlipoproteinaemic patients sho... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/2613482"
} |
MED-1768 | Is milk responsible for male reproductive disorders? | The role of environmental compounds with estrogenic activity in the development of male reproductive disorders has been a source of great concern. Among the routes of human exposure to estrogens, we are particularly concerned about cows' milk, which contains considerable amounts of estrogens. The major sources of anima... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/11601881"
} |
MED-1770 | Possible health impact of animal oestrogens in food. | Oestrogens govern reproductive functions in vertebrates, and are present in all animal tissues. The theoretical maximum daily intake (TMDI) of oestradiol-17beta by consumption of cattle meat is calculated to be 4.3 ng. Following the use of oestradiol-containing growth-promoting agents, TMDI is increased by a factor of ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/11392381"
} |
MED-1771 | Some observations on human semen analysis. | Semen analysis of 66 unmarried medical students in the age group of 17-21 years was carried out. A higher liquefaction time pH, motility, lower sperm count and abnormal forms were observed compared to reported values. Liquefaction time, pH and sperm count was found significantly different in non-vegetarians and vegetar... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/35465"
} |
MED-1773 | Dairy food intake in relation to semen quality and reproductive hormone levels among physically active young men | STUDY QUESTION Is increased consumption of dairy foods associated with lower semen quality? SUMMARY ANSWER We found that intake of full-fat dairy was inversely related to sperm motility and morphology. These associations were driven primarily by intake of cheese and were independent of overall dietary patterns. WHAT IS... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23670169"
} |
MED-1774 | A national survey of persistent, bioaccumulative, and toxic (PBT) pollutants in the United States milk supply. | This study measured 21 persistent, bioaccumulative, and toxic (PBT) pollutants in the US milk supply. Since milk fat is likely to be among the highest dietary sources of exposure to PBTs, it is important to understand their levels in this food. Nationwide samples were collected from 45 dairy plants in July of 2000 and ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/12743612"
} |
MED-1775 | Comparison of individual antioxidants of sperm and seminal plasma in fertile and infertile men. | OBJECTIVE: To measure individual antioxidants in sperm and seminal plasma from fertile and infertile men to determine if any particular antioxidant is reduced in infertile men. DESIGN: Semen samples were prepared by a discontinuous Percoll gradient to separate sperm and seminal plasma, and the antioxidant concentration... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/8986699"
} |
MED-1776 | Semen quality trends in French regions are consistent with a global change in environmental exposure. | A retrospective study carried out recently in a large sample of men, close to the general population, has reported a significant and strong decline in sperm concentration and morphology in the whole of France between 1989 and 2005. We studied these trends within each region of France. Data were obtained from the Fivnat... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24567426"
} |
MED-1777 | Shedding Light on the Controversy Surrounding the Temporal Decline in Human Sperm Counts: A Systematic Review | We systematically examined the evidence of declining sperm counts and the hypothesis that an increased exposure to environmental pollutants is responsible for such decline. Search engines, including PUBMED, MEDLINE, EMBASE, BIOSIS, and Cochrane library, were used to identify epidemiologic studies published from 1985 to... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24672311"
} |
MED-1778 | Dairy intake and semen quality among men attending a fertility clinic | Objective To examine the relationship between dairy food intake and semen parameters Design Longitudinal study Setting Men attending academic medical center fertility clinic in Boston, MA Patients 155 men Interventions None Main Outcome Measures total sperm count, sperm concentration, progressive motility, and morpholo... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24636397"
} |
MED-1779 | The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility. | The imbalance between reactive oxygen species (ROS) production and total antioxidant capacity (TAC) in seminal fluid indicates oxidative stress and is correlated with male infertility. A composite ROS-TAC score may be more strongly correlated with infertility than ROS or TAC alone. We measured ROS, TAC, and ROS-TAC sco... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/10548626"
} |
MED-1780 | What has happened to human fertility? | Semen quality appears to have declined in recent decades in some populations, e.g. north-western Europe. At the same time, couple fertility may have increased. Hypotheses are suggested for this apparent inconsistency. Alongside the deterioration of spermatogenesis there is clear evidence of an increase in other related... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/19933234"
} |
MED-1781 | High dietary intake of saturated fat is associated with reduced semen quality among 701 young Danish men from the general population. | BACKGROUND: Saturated fat intake has been associated with both cardiovascular disease and cancer risk, and a newly published study found an association between saturated fat intake and a lower sperm concentration in infertile men. OBJECTIVE: The objective was to examine the association between dietary fat intake and se... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23269819"
} |
MED-1782 | Antioxidants to reduce sperm DNA fragmentation: an unexpected adverse effect. | Reactive oxygen species (ROS) have a negative impact on sperm DNA, leading to the formation of oxidative products such as 8-oxo-7,8-dihydroxyguanosine. This compound causes fragmentation and, thus, has a mutagenic effect. Patient treatment with oral antioxidant vitamins is, therefore, standard practice for male inferti... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/17425820"
} |
MED-1783 | SEMEN QUALITY IN RELATION TO ANTIOXIDANT INTAKE IN A HEALTHY MALE POPULATION | Objective To assess the relationship between dietary antioxidant intake and semen quality in young healthy males Design Cross-sectional study Setting University and college campuses in the Rochester, New York, area Patients 189 university-aged men Interventions None Main Outcome Measures Semen volume, total sperm count... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24094424"
} |
MED-1784 | Association between sperm quality, oxidative stress, and seminal antioxidant activity. | OBJECTIVES: To determine seminal antioxidant capacity, oxidative stress markers, and their association with semen quality as oxidative stress is considered to be a major etiological factor in male infertility. SUBJECTS AND METHODS: Semen samples were obtained from 138 men and categorized on the basis of sperm count, mo... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21145315"
} |
MED-1785 | Walnuts improve semen quality in men consuming a Western-style diet: randomized control dietary intervention trial. | We tested the hypothesis that 75 g of whole-shelled walnuts/day added to the Western-style diet of healthy young men would beneficially affect semen quality. A randomized, parallel two-group dietary intervention trial with single-blind masking of outcome assessors was conducted with 117 healthy men, age 21-35 yr old, w... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22895856"
} |
MED-1786 | Good semen quality and life expectancy: a cohort study of 43,277 men. | Fertility status may predict later mortality, but no studies have examined the effect of semen quality on subsequent mortality. Men referred to the Copenhagen Sperm Analysis Laboratory by general practitioners and urologists from 1963 to 2001 were, through a unique personal identification number, linked to the Danish c... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/19635736"
} |
MED-1787 | Evidence for decreasing quality of semen during past 50 years. | OBJECTIVE: To investigate whether semen quality has changed during the past 50 years. DESIGN: Review of publications on semen quality in men without a history of infertility selected by means of Cumulated Index Medicus and Current List (1930-1965) and MEDLINE Silver Platter database (1966-August 1991). SUBJECTS: 14,947... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/1393072"
} |
MED-1788 | Micronutrients intake is associated with improved sperm DNA quality in older men. | OBJECTIVE: To investigate whether lifestyle factors such as increased dietary intake of micronutrients reduce the risks of sperm DNA damage, and whether older men benefit more than younger men. DESIGN: Cross-sectional study design with equalized assignments into age groups. SETTING: National laboratory and university. ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22935557"
} |
MED-1789 | Nonextractable polyphenols, usually ignored, are the major part of dietary polyphenols: a study on the Spanish diet. | SCOPE: Dietary polyphenols (PP) can be divided into two groups: extractable polyphenols (EPP) or compounds solubilized by aqueous organic solvents, and nonextractable polyphenols (NEPP) or compounds that remain in their corresponding extraction residues. Most studies on food polyphenols and dietary intakes address excl... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/20540148"
} |
MED-1790 | Reducing Childhood Obesity by Eliminating 100% Fruit Juice | The Healthy Hunger-Free Kids Act of 2010 presents an opportunity to change the nutritional quality of foods served in low-income childcare centers, including Head Start centers. Excessive fruit juice consumption is associated with increased risk for obesity. Moreover, there is recent scientific evidence that sucrose co... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22813423"
} |
MED-1791 | A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. | BACKGROUND: Short-term studies in adolescents have generally shown an enhancement of calcium absorption by inulin-type fructans (prebiotics). Results have been inconsistent; however, and no studies have been conducted to determine whether this effect persists with long-term use. OBJECTIVE: The objective was to assess t... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/16087995"
} |
MED-1792 | Intake of whole apples or clear apple juice has contrasting effects on plasma lipids in healthy volunteers. | PURPOSE: Fruit consumption is associated with a decreased risk of CVD in cohort studies and is therefore endorsed by health authorities as part of the '5 or more a day' campaigns. A glass of fruit juice is generally counted as one serving. Fruit may cause protection by affecting common risk factors of CVD. METHODS: App... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23271615"
} |
MED-1793 | Concept and health-related properties of nonextractable polyphenols: the missing dietary polyphenols. | Most research studies in the field of dietary polyphenols or phenolic compounds use a chemical approach focusing exclusively on polyphenols extracted from plant foods with organic solvents. However, an appreciable part of polyphenols are not extracted with organic solvents and thus are ignored in biological, nutritiona... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23095074"
} |
MED-1794 | Dietary roles of non-starch polysaccharides in human nutrition: a review. | Nonstarch polysaccharides (NSPs) occur naturally in many foods. The physiochemical and biological properties of these compounds correspond to dietary fiber. Nonstarch polysaccharides show various physiological effects in the small and large intestine and therefore have important health implications for humans. The rema... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22747080"
} |
MED-1795 | Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies | Objective To determine whether individual fruits are differentially associated with risk of type 2 diabetes. Design Prospective longitudinal cohort study. Setting Health professionals in the United States. Participants 66 105 women from the Nurses’ Health Study (1984-2008), 85 104 women from the Nurses’ Health Study II... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23990623"
} |
MED-1796 | Association of Adenovirus 36 Infection with Obesity and Metabolic Markers in Humans: A Meta-Analysis of Observational Studies | Background Several studies have shown that Adenovirus 36 (Ad36) influences the risk of obesity in humans. Clarifying the relationship between Ad36 infection and obesity could lead to more effective approaches for the management of obesity. The objective of this study was to conduct a meta-analysis to confirm the influe... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22848697"
} |
MED-1797 | Comparative genome analysis with the human genome reveals chicken genes associated with fatness and body weight. | The selection of meat-type chickens (broilers) for rapid growth has been accompanied by excessive fat deposition. In this study, we analysed 53 candidate genes that are associated with obesity and obesity-related traits in humans, for which we found chicken orthologues by BLAST searches. We have identified single nucle... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22035006"
} |
MED-1798 | Adenovirus 36 infection and obesity. | The most important factors leading to fat accumulation in children are genetic inheritance, endocrine alterations, and behavioural/environmental causes. In addition, experimental animal studies have shown that infections due to various pathogens can lead to overweight and obesity conditions, and studies of humans have ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22771001"
} |
MED-1799 | Adipogenic Human Adenovirus Ad-36 Induces Commitment, Differentiation, and Lipid Accumulation in Human Adipose-Derived Stem Cells | Human adenovirus Ad-36 is causatively and correlatively linked with animal and human obesity, respectively. Ad-36 enhances differentiation of rodent preadipocytes, but its effect on adipogenesis in humans is unknown. To indirectly assess the role of Ad-36-induced adipogenesis in human obesity, the effect of the virus o... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/18203674"
} |
MED-1800 | Adenovirus-36 Is Associated with Obesity in Children and Adults in Sweden as Determined by Rapid ELISA | Background Experimental and natural human adenovirus-36 (Adv36) infection of multiple animal species results in obesity through increasing adipogenesis and lipid accumulation in adipocytes. Presence of Adv36 antibodies detected by serum neutralization assay has previously been associated with obesity in children and ad... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22848557"
} |
MED-1801 | Modern organic and broiler chickens sold for human consumption provide more energy from fat than protein. | OBJECTIVE: In 1976, the Royal College of Physicians and the British Cardiac Society recommended eating less fatty red meat and more poultry instead because it was lean. However, the situation has changed since that time, with a striking increase in fat content of the standard broiler chicken. The aim of the present stu... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/19728900"
} |
MED-1802 | Longitudinal changes in BMI in older adults are associated with meat consumption differentially, by type of meat consumed. | Hypotheses regarding the role of meat consumption in body weight modulation are contradictory. Prospective studies on an association between meat consumption and BMI change are limited. We assessed the association between meat consumption and change in BMI over time in 3902 men and women aged 55-69 y from the Netherlan... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22223576"
} |
MED-1803 | A framework for identification of infections that contribute to human obesity. | WHO has declared obesity to be a global epidemic. Obesity management strategies mainly target behavioural components of the disorder, but are only marginally effective. A comprehensive understanding of the causative factors of obesity might provide more effective management approaches. Several microbes are causatively ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22115071"
} |
MED-1804 | Human adenovirus-36 and childhood obesity. | There is increasing evidence that obesity in humans is associated with infection with human adenovirus-36 (Adv36). Infection of experimental animals with Adv36 demonstrates that this virus causes obesity. Human studies have shown a prevalence of Adv36 infection of 30% or greater in obese adult humans, but a correlation... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21905809"
} |
MED-1806 | Long-Term Changes in Adiposity and Glycemic Control Are Associated With Past Adenovirus Infection | OBJECTIVE Ad36, a human adenovirus, increases adiposity but improves glycemic control in animal models. Similarly, natural Ad36 infection is cross-sectionally associated with greater adiposity and better glycemic control in humans. This study compared longitudinal observations in indices of adiposity (BMI and body fat ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23160725"
} |
MED-1807 | Intake of total, animal and plant protein and subsequent changes in weight or waist circumference in European men and women: the Diogenes project. | BACKGROUND: As protein is considered to increase thermogenesis and satiety more than other macronutrients, it may have beneficial effects on prevention of weight gain and weight maintenance. OBJECTIVE: The objective of this study is to assess the association between the amount and type of dietary protein, and subsequen... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21139559"
} |
MED-1808 | Human adenovirus-36 antibody status is associated with obesity in children. | BACKGROUND: Human adenovirus-36 (Ad-36) is thought to induce obesity by a direct effect of the viral E4orf1 gene on lipogenic enzymes in host adipocytes. Ad-36 prevalence is 30% in obese adults, but prevalence has not been reported in childhood obesity. OBJECTIVES: To determine the prevalence of Ad-36 infection in obes... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/19593728"
} |
MED-1810 | Transmissibility of adenovirus-induced adiposity in a chicken model. | BACKGROUND: We previously reported that human adenovirus Ad-36 induces adiposity and paradoxically lower levels of serum cholesterol (CHOL) and triglycerides (TG) in animals. OBJECTIVE: To evaluate the transmissibility of Ad-36 and Ad-36 induced adiposity using a chicken model. DESIGN: Experiment 1--four chickens were ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/11443497"
} |
MED-1811 | A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients. | BACKGROUND: A growing number of preclinical studies have demonstrated that curcumin could be a promising anticancer drug; however, poor bioavailability has been the major obstacle for its clinical application. To overcome this problem, we developed a new form of curcumin (Theracurmin) and reported high plasma curcumin ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23543271"
} |
MED-1812 | Dietary habits and past medical history as related to fatal pancreas cancer risk among Adventists. | Epidemiologic studies of diet and pancreas cancer are few, and include ecologic comparisons and a limited number of prospective and case-control studies. Foods and/or nutrients that have been suggested to be associated with increased risk of this cancer include total fat intake, eggs, animal protein, sugar, meat, coffe... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/3365678"
} |
MED-1813 | Phase II trial of curcumin in patients with advanced pancreatic cancer. | PURPOSE: Pancreatic cancer is almost always lethal, and the only U.S. Food and Drug Administration-approved therapies for it, gemcitabine and erlotinib, produce objective responses in <10% of patients. We evaluated the clinical biological effects of curcumin (diferuloylmethane), a plant-derived dietary ingredient with ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/18628464"
} |
MED-1814 | Dietary patterns and risk of pancreatic cancer in a large population-based case-control study in the San Francisco Bay Area | Pancreatic cancer is highly lethal, and identifying modifiable risk factors could have substantial public health impact. In this population-based case-control study (532 cases, 1701 controls), we used principal component analysis and multivariable unconditional logistic regression models to examine whether a particular... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23368926"
} |
MED-1817 | Meat and fish consumption and risk of pancreatic cancer: results from the European Prospective Investigation into Cancer and Nutrition. | Pancreatic cancer is the fourth most common cause of cancer death worldwide with large geographical variation, which implies the contribution of diet and lifestyle in its etiology. We examined the association of meat and fish consumption with risk of pancreatic cancer in the European Prospective Investigation into Canc... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22610753"
} |
MED-1818 | Nutrient-based dietary patterns and pancreatic cancer risk. | PURPOSE: Few data are available on the role of combinations of foods and/or nutrients on pancreatic cancer risk. To add further information on dietary patterns potentially associated to pancreatic cancer, we applied an exploratory principal component factor analysis on 28 major nutrients derived from an Italian case-co... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23332711"
} |
MED-1819 | Potentiation of gemcitabine by Turmeric Force in pancreatic cancer cell lines. | Gemcitabine is a first line cancer drug widely used for the treatment of pancreatic cancer. However, its therapeutic efficiency is significantly limited by resistance of pancreatic cancer cells to this and other chemotherapeutic drugs. We have investigated the cytotoxic effect of Turmeric Force (TF), a supercritical an... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/20428806"
} |
MED-1820 | Gemcitabine Plus Erlotinib for Advanced Pancreatic Cancer: A Systematic Review with Meta-Analysis | Background This study aims to comprehensively summarize the currently available evidences on the efficacy and safety of gemcitabine plus erlotinib for treating advanced pancreatic cancer. Methodology/Principal Findings PubMed, EMBASE, The Cochrane Library and abstracts of recent major conferences were systematically se... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23472089"
} |
MED-1825 | Flax and Breast Cancer: A Systematic Review. | Background. Flax is a food and dietary supplement commonly used for menopausal symptoms. Flax is known for its lignan, α-linolenic acid, and fiber content, components that may possess phytogestrogenic, anti-inflammatory, and hormone modulating effects, respectively. We conducted a systematic review of flax for efficacy... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24013641"
} |
MED-1826 | Consumption of flaxseed, a rich source of lignans, is associated with reduced breast cancer risk. | PURPOSE: To investigate the association between intake of flaxseed-the richest source of dietary lignans (a class of phytoestrogens)-and breast cancer risk. METHODS: A food frequency questionnaire was used to measure the consumption of flaxseed and flax bread by 2,999 women with breast cancer and 3,370 healthy control ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23354422"
} |
MED-1827 | In vitro anti-metastatic activity of enterolactone, a mammalian lignan derived from flax lignan, and down-regulation of matrix metalloproteinases i... | BACKGROUND: Actin cytoskeleton is involved in actin-based cell adhesion, cell motility, and matrix metalloproteinases(MMPs) MMP2, MMP9, MMP11 and MMP14 are responsible for cell invasion in breast cancer metastasis. The dietary intake of lignan from flax seed gets converted to enterolactone (EL) and enterodiol in the hu... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22842186"
} |
MED-1828 | Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas chromatography-mass sp... | The first quantitative method for the determination of both lignans and isoflavonoid phytoestrogens in plasma is presented. Using ion-exchange chromatography the diphenols are separated into two fractions 1) the biologically "active" fraction containing the free compounds + mono- and disulfates and 2) the biologically ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/8392221"
} |
MED-1829 | Estradiol, tamoxifen, and flaxseed alter IL-1β and IL-1Ra levels in normal human breast tissue in vivo. | INTRODUCTION: Sex steroid exposure increases the risk of breast cancer by unclear mechanisms. Diet modifications may be one breast cancer prevention strategy. The proinflammatory cytokine family of IL-1 is implicated in cancer progression. IL-1Ra is an endogenous inhibitor of the proinflammatory IL-1α and IL-1β. OBJECT... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22930784"
} |
MED-1830 | Exploration of 100 commonly used drugs and supplements on cognition in older adults | Background There are conflicting reports and a lack of evidence-based data regarding effects of medications on cognition in cognitively normal older adults. We explored whether use of 100 common medications taken by older adults is associated with longitudinal cognitive performance. Methods A longitudinal observational... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23954027"
} |
MED-1831 | Children's daily exposure to polychlorinated biphenyls from dietary supplements containing fish oils. | In children, omega-3 polyunsaturated fatty acids (PUFAs) may elicit a suite of health benefits including enhancement of cognitive development. Subsequently, dietary supplements containing omega-3 PUFAs have become increasingly popular. Often, the largest source of beneficial PUFAs in these supplements is fish oil, whic... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23281830"
} |
MED-1832 | Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. | The need for a dietary supply of docosahexaenoic acid (DHA) and arachidonic aid (AA) in term infants was evaluated in a double-masked randomized clinical trial of the effects of supplementation of term infant formula with DHA (0.35% of total fatty acids) or with DHA (0.36%) and AA (0.72%) on visual acuity development. ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/9702915"
} |
MED-1833 | Cod liver oil intake and incidence of asthma in Norwegian adults--the HUNT study. | BACKGROUND: Cod liver oil is an important source of vitamin D, but also contains other fat-soluble components such as vitamin A. Before 1999, the cod liver oil formula in Norway contained a high concentration of vitamin A (1000 µg per 5 ml). High vitamin A status is associated with increased risks of several chronic di... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22977130"
} |
MED-1834 | The role of latitude, ultraviolet radiation exposure and vitamin D in childhood asthma and hayfever: an Australian multicenter study. | Observations of increasing allergy prevalence with decreasing distance from the Equator and positive associations with ambient ultraviolet radiation have contributed to a growing interest in the possible role of vitamin D in the etiology of allergy. The aims of this study were to describe any latitudinal variation in t... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/20880353"
} |
MED-1836 | Longitudinal changes of manganese-dependent superoxide dismutase and other indexes of manganese and iron status in women. | The effect of dietary factors on manganese-dependent superoxide dismutase (MnSOD) activity in humans has not been studied. We longitudinally evaluated changes in MnSOD activity and other indices of manganese and iron status in 47 women during a 124-d supplementation study. Subjects received one of four treatments: plac... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/1550052"
} |
MED-1837 | Dietary manganese intake and type of lipid do not affect clinical or neuropsychological measures in healthy young women. | Because manganese (Mn) is potentially toxic, and because dietary fat type may affect Mn absorption, the objectives of the current study were to determine whether diets containing very low or very high amounts of Mn and enriched in either saturated or unsaturated fats affected measures of neuropsychological and basic me... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/12949376"
} |
MED-1838 | Aluminium and other elements in selected herbal tea plant species and their infusions. | The determination of Al, B, Cu, Fe, Mn, Ni, P, Zn and Ca, K, Mg by inductively coupled plasma optical emission spectrometry (ICP-OES) and flame atomic absorption spectroscopy (FAAS), respectively, in digests and infusions of Hibiscus sabdariffa (petals), Rosa canina (receptacles), Ginkgo biloba (leaves), Cymbopogon cit... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23561167"
} |
MED-1839 | Gastrointestinal absorption of aluminium from single doses of aluminium containing antacids in man. | Ten subjects with normal renal function were given different single doses of aluminium containing antacids (1, 4, or 8 tablets). The antacid tablets (aluminium content 244 mg tablet-1) were chewed and swallowed either with water, with orange juice, or with citric acid solution. There was a marked increase in serum conc... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/3100311"
} |
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