_id stringlengths 6 8 | title stringlengths 10 234 | text stringlengths 90 9.94k | metadata dict |
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MED-1840 | Influence of tea drinking on manganese intake, manganese status and leucocyte expression of MnSOD and cytosolic aminopeptidase P. | OBJECTIVE: Since black tea contains high levels of manganese (Mn), we investigated the relationship between dietary Mn intake, circulating Mn levels and leucocyte expression of two Mn-dependent enzymes in tea drinkers and non-tea drinkers. DESIGN: We assessed Mn intakes (food frequency questionnaire), fasting whole blo... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/16118651"
} |
MED-1841 | Dietary citric acid enhances absorption of aluminum in antacids. | Ten healthy men ingested, twice daily between meals, during each of the seven-day experimental periods: (a) citric acid (as lemon juice), (b) Al(OH)3, or (c) Al(OH)3 + citric acid. Whole blood sampled after each dietary period was analyzed electrothermally after digestion with nitric acid. Moderate, but significant, in... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/3948402"
} |
MED-1842 | The effect of sour tea (Hibiscus sabdariffa) on essential hypertension. | Considering the high prevalence of hypertension, its debilitating end organ damage, and the side effects of chemical drugs used for its treatment, we conducted this experimental study to evaluate the effect of sour tea (Hibiscus sabdariffa) on essential hypertension. For this purpose, 31 and 23 patients with moderate e... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/10404421"
} |
MED-1843 | Aluminium in over-the-counter drugs: risks outweigh benefits? | In the early 1970s, aluminium toxicity was first implicated in the pathogenesis of clinical disorders in patients with chronic renal failure involving bone (renal osteomalacia) or brain tissue (dialysis encephalopathy). Before that time the toxic effects of aluminium ingestion were not considered to be a major concern ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/14583063"
} |
MED-1844 | Determination of total aluminum, chromium, copper, iron, manganese, and nickel and their fractions leached to the infusions of black tea, green tea... | Total aluminum, chromium, copper, iron, manganese, and nickel were determined in black tea, green tea, Hibiscus sabdariffa, and Ilex paraguariensis (mate) by electrothermal atomic absorption spectrometry after nitric/perchloric acid digestion. In each case, one ground sample of commercially available leafy material was... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/11314985"
} |
MED-1845 | Plasma levels of aluminium after tea ingestion in healthy volunteers. | 12 healthy volunteers on a controlled aluminium (Al) diet each consumed a tea infusion (500 ml/70 kg body weight), with either milk or lemon juice as additives, or mineral water, following a three-way crossover design. The concentrations of Al were determined in the diet, mineral water and tea infusions, and in plasma ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/8444383"
} |
MED-1846 | The effects of fruit juices and fruits on the absorption of iron from a rice meal. | The effects of the chemical composition of fruit juices and fruit on the absorption of iron from a rice (Oryza sativa) meal were measured in 234 parous Indian women, using the erythrocyte utilization of radioactive Fe method. The corrected geometric mean Fe absorptions with different juices varied between 0.040 and 0.1... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/3593665"
} |
MED-1847 | Gastro-intestinal availability of aluminium from tea. | The in vitro speciation of aluminium (Al) in black tea infusion (pH 4.8) was assessed using 3000, 10,000 and 30,000 Da cut-off ultrafilters, and the effect of adding human gastric juice (pH 2.3) and then raising the pH to 6.5 were also studied. 78% Al in the tea infusion passed through the 3000-Da ultrafilter; this per... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/8514217"
} |
MED-1848 | Neurotoxic effects of aluminium among foundry workers and Alzheimer's disease. | BACKGROUND: In a cross-sectional case-control study conducted in northern Italy, 64 former aluminium dust-exposed workers were compared with 32 unexposed controls from other companies matched for age, professional training, economic status, educational and clinical features. The findings lead the authors to suggest a p... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/12520766"
} |
MED-1849 | Aluminum involvement in the progression of Alzheimer's disease. | The neuroanatomic specificity with which Alzheimer's disease (AD) progresses could provide clues to AD etiopathology. Magnetic resonance imaging studies of AD clinical progression have confirmed general conclusions from earlier studies of AD neuropathological progression wherein neurofibrillary tangle pathology was obs... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23380995"
} |
MED-1850 | Urine levels of aluminum after drinking tea. | A microwave-assisted acid digestion procedure coupled with a graphite furnace atomic absorption method has been applied in the determination of aluminum (Al) in urine to verify the correlation of free forms of Al in tea infusions and urinary excretion of Al. Significant urinary Al excretion has been found in 24-h urine... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/9359993"
} |
MED-1851 | Aluminum and Alzheimer's disease: after a century of controversy, is there a plausible link? | The brain is a highly compartmentalized organ exceptionally susceptible to accumulation of metabolic errors. Alzheimer's disease (AD) is the most prevalent neurodegenerative disease of the elderly and is characterized by regional specificity of neural aberrations associated with higher cognitive functions. Aluminum (Al... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21157018"
} |
MED-1852 | Aluminium migration into beverages: are dented cans safe? | Aluminium (Al) migration from cans to beer and tea was studied along time. Analyses of Al in the canned drinks were performed till the sell-by date, and, in seven months, aluminium migration was found to increase 0.14 mg L(-1) in beer, and 0.6 mg L(-1) in tea. This study included dented cans from which aluminium migrat... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/18672271"
} |
MED-1853 | Erosive potentials of brewed teas. | PURPOSE: To measure the pH, titratable acidity, fluoride concentration and erosive potential of brewed teas. METHODS: Bag teas were purchased to represent black, green, citrus, fruity, and floral tea flavors from Tulsi, Bigelow, HyVee, Tazo, and Yogi brands and brewed (1 bag/240 ml) in boiling water for 3 minutes. The ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24479280"
} |
MED-1857 | Periodontal conditions in vegetarians: a clinical study. | BACKGROUND/OBJECTIVES: Investigations about possible correlations between vegetarian diet and periodontal conditions are rare and characterized by small case numbers. The aim of this clinical study was to investigate the influence of a vegetarian diet on periodontal parameters with an appropriate sample size. SUBJECTS/... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23714722"
} |
MED-1858 | Influence of drinking patterns of carbonated beverages on dental erosion. | As a hard tissue dental disease, dental erosion has a multifactorial etiology. The majority of dental erosion that originates from extrinsic sources is the result of dietary intake, particularly acidic beverages. Several preventive means have been proposed to minimize the damage to the dentition, including a reduction ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/15960479"
} |
MED-1859 | Roselle (Hibiscus sabdariffa L.) and soybean oil effects on quality characteristics of pork patties studied by response surface methodology. | Response surface methodology was used to investigate the effect and interactions of processing variables such as roselle extract (0.1-1.3%), soybean oil (5-20%) on physicochemical, textural and sensory properties of cooked pork patties. It was found that reduction in thickness, pH, L* and b* values decreased; however, ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23567142"
} |
MED-1860 | The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes. | To compare the antihypertensive effectiveness of sour tea (ST; Hibiscus sabdariffa) with black tea (BT) infusion in diabetic patients, this double-blind randomized controlled trial was carried out. Sixty diabetic patients with mild hypertension, without taking antihypertensive or antihyperlipidaemic medicines, were rec... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/18685605"
} |
MED-1861 | The effectiveness of Hibiscus sabdariffa in the treatment of hypertension: a systematic review. | INTRODUCTION: Hypertension is a common global health problem with significant mortality and morbidity. Hibiscus sabdariffa is a plant known in many countries and is consumed as hot and cold drinks In addition to its use in folk medicine; it has been suggested as treatment for many conditions including hypertension. OBJ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/19801187"
} |
MED-1862 | Effects of comprehensive lifestyle modification on diet, weight, physical fitness, and blood pressure control: 18-month results of a randomized trial. | BACKGROUND: The main 6-month results from the PREMIER trial showed that comprehensive behavioral intervention programs improve lifestyle behaviors and lower blood pressure. OBJECTIVE: To compare the 18-month effects of 2 multicomponent behavioral interventions versus advice only on hypertension status, lifestyle change... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/16585662"
} |
MED-1863 | Vegetarian diets and blood pressure: a meta-analysis. | IMPORTANCE Previous studies have suggested an association between vegetarian diets and lower blood pressure (BP), but the relationship is not well established. OBJECTIVE To conduct a systematic review and meta-analysis of controlled clinical trials and observational studies that have examined the association between ve... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24566947"
} |
MED-1864 | Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: a comprehensive review of animal and human studies | The effectiveness of Hibiscus sabdariffa L. (HS) in the treatment of risk factors associated with cardiovascular disease is assessed in this review by taking a comprehensive approach to interpreting the randomized clinical trial (RCT) results in the context of the available ethnomedical, phytochemical, pharmacological,... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23333908"
} |
MED-1865 | Hibiscus sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. | In vitro studies show Hibiscus sabdariffa L., an ingredient found in many herbal tea blends and other beverages, has antioxidant properties, and, in animal models, extracts of its calyces have demonstrated hypocholesterolemic and antihypertensive properties. Our objective in this study was to examine the antihypertensi... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/20018807"
} |
MED-1866 | Hibiscus sabdariffa extract lowers blood pressure and improves endothelial function. | Polyphenols from Hibiscus sabdariffa calices were administered to patients with metabolic syndrome (125 mg/kg/day for 4 wk, n = 31) and spontaneously hypertensive rats (125 or 60 mg/kg in a single dose or daily for 1 wk, n = 8 for each experimental group). The H. sabdariffa extract improved metabolism, displayed potent... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24668839"
} |
MED-1867 | Effects of sour tea (Hibiscus sabdariffa) on lipid profile and lipoproteins in patients with type II diabetes. | OBJECTIVES: There is increasing evidence that intake of sour tea (Hibiscus sabdariffa) has hypoglycemic and hypolipidemic effects and may benefit patients suffering from metabolic disorders such as diabetes. The objective of the present study was to investigate the hypolipidemic effects of sour tea in patients with dia... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/19678781"
} |
MED-1868 | Hibiscus sabdariffa extract inhibits obesity and fat accumulation, and improves liver steatosis in humans. | Obesity is associated with a great diversity of diseases including non-alcoholic fatty liver disease. Our previous report suggested that Hibiscus sabdariffa extracts (HSE) had a metabolic-regulating and liver-protecting potential. In this study, we performed a clinical trial to further confirm the effect of HSE. Subjec... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24549255"
} |
MED-1869 | The relationship between dietary protein intake and blood pressure: results from the PREMIER study. | Observational and clinical studies suggest that high protein intake, particularly protein from plant sources, might reduce blood pressure (BP). To examine the association of dietary protein with BP, we analysed data from PREMIER, an 18-month clinical trial (n=810) that examined the effects of two multi-component lifest... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/18580887"
} |
MED-1871 | Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and ... | In order to compare the antihypertensive effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa with captopril, a controlled and randomized clinical trial was done. Patients from 30 to 80 years old with diagnosed hypertension and without antihypertensive treatment for at least 1 month before ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/15330492"
} |
MED-1872 | Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial. | CONTEXT: Weight loss, sodium reduction, increased physical activity, and limited alcohol intake are established recommendations that reduce blood pressure (BP). The Dietary Approaches to Stop Hypertension (DASH) diet also lowers BP. To date, no trial has evaluated the effects of simultaneously implementing these lifest... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/12709466"
} |
MED-1873 | Dietary saturated fat intake is negatively associated with weight maintenance among the PREMIER participants. | Research finding on the composition of macronutrient intakes on body weight has not been consistent. Furthermore, little research has examined the impact of subcomponents of macronutrients such as saturated fat or plant protein on body weight. The purpose of this report was to examine the impact of saturated fat, anima... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21331065"
} |
MED-1874 | The Garden of Eden--plant based diets, the genetic drive to conserve cholesterol and its implications for heart disease in the 21st century. | It is likely that plant food consumption throughout much of human evolution shaped the dietary requirements of contemporary humans. Diets would have been high in dietary fiber, vegetable protein, plant sterols and associated phytochemicals, and low in saturated and trans-fatty acids and other substrates for cholesterol... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/?term=The+Garden+of+Eden%E2%80%94plant+based+diets%2C+the+genetic+drive+to+conserve+cholesterol+and+its+implications+for+heart+disease+in+the+21st+century%22"
} |
MED-1876 | Consumption of whole grain reduces risk of deteriorating glucose tolerance, including progression to prediabetes. | BACKGROUND: High whole-grain intake has been reportedly associated with reduced risk of developing type 2 diabetes (T2D), which is an effect possibly subject to genetic effect modification. Confirmation in prospective studies and investigations on the impact on prediabetes is needed. OBJECTIVES: In a prospective popula... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23235198"
} |
MED-1878 | Crossing the Quality Chasm: A New Health System for the 21st Century | Excerpt Second in a series of publications from the Institute of Medicine's Quality of Health Care in America project Today's health care providers have more research findings and more technology available to them than ever before. Yet recent reports have raised serious doubts about the quality of health care in Americ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/25057539"
} |
MED-1879 | Daily flaxseed consumption improves glycemic control in obese men and women with pre-diabetes: a randomized study. | The study hypothesis was that fasting glucose, insulin, fructosamine, C-reactive protein, and interleukin-6 decrease and adiponectin increases with daily flaxseed consumption in overweight or obese individuals with pre-diabetes. In this randomized, cross-over study overweight or obese men and postmenopausal women (n = ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23684438"
} |
MED-1880 | Effect of cooking and germination on phenolic composition and biological properties of dark beans (Phaseolus vulgaris L.). | Legumes are the basés diet in several countries. They hold a high nutritional value, but other properties related to human health are nowadays being studied. The aim of this work was to study the influence of processes (boiling or germination) on the phenolic composition of dark beans (Phaseolus vulgaris L. c.v. Tolosa... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23265523"
} |
MED-1881 | Lower intake of vegetables and legumes associated with cognitive decline among illiterate elderly Chinese: a 3-year cohort study. | BACKGROUND: Despite many studies on cognitive function and its influential factors among old population, relatively little research has been designed to study the relationship between dietary intake and cognitive function in elderly. OBJECTIVE: We conducted a population-based, prospective nested case-control study to i... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22659995"
} |
MED-1882 | Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy i... | BACKGROUND: Changes in conventional lipid risk factors with gemfibrozil treatment only partially explain the reductions in coronary heart disease (CHD) events experienced by men in the Veterans Affairs High-Density Lipoprotein Intervention Trial (VA-HIT). We examined whether measurement of low-density lipoprotein (LDL)... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/16534013"
} |
MED-1884 | Maintenance of the LDL cholesterol:HDL cholesterol ratio in an elderly population given a dietary cholesterol challenge. | We previously evaluated the responses to dietary cholesterol in children and young adults. In this study, the effects of dietary cholesterol on plasma lipids and LDL atherogenicity were evaluated in 42 elderly subjects (29 postmenopausal women and 13 men > 60 y old). Our exclusion criteria were diabetes, heart disease,... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/16317122"
} |
MED-1885 | Rethinking dietary cholesterol. | PURPOSE OF REVIEW: The perceived notion that dietary cholesterol is associated with increased risk for coronary heart disease (CHD) has led to dietary recommendations of no more than 300 mg/day for healthy populations in the USA. This study will review the recent evidence that challenges the current dietary restrictio... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22037012"
} |
MED-1886 | Lipoprotein Particle Profiles by Nuclear Magnetic Resonance Compared with Standard Lipids and Apolipoproteins in Predicting Incident Cardiovascular Disease in Women | Background Nuclear magnetic resonance (NMR) spectroscopy measures the number and size of lipoprotein particles, instead of their cholesterol or triglyceride content, but its clinical utility is uncertain. Methods and Results Baseline lipoproteins were measured by NMR in 27,673 initially healthy women followed for incid... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/19204302"
} |
MED-1887 | What is the role of advanced lipoprotein analysis in practice? | Some practitioners use advanced lipoprotein analysis with the goal of better predicting risk and individualizing lifestyle and drug therapy for cardiovascular prevention. Unfortunately, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particle number and size, other lipoprotein subfractionation, apolipo... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23257303"
} |
MED-1888 | Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk | BACKGROUND Recent studies in animals have shown a mechanistic link between intestinal microbial metabolism of the choline moiety in dietary phosphatidylcholine (lecithin) and coronary artery disease through the production of a proatherosclerotic metabolite, trimethylamine-N-oxide (TMAO). We investigated the relationshi... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23614584"
} |
MED-1889 | Consumption of eggs with meals increases the susceptibility of human plasma and low-density lipoprotein to lipid peroxidation. | Consumption of eggs for a long period was shown to result in hypercholesterolemia and is generally restricted for this reason. In the present study we analyzed the effect of eggs consumption for 3 weeks on lipoprotein atherogenicity. Consumption of 2 eggs per day with the meals, for 3 weeks resulted in a minor elevatio... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/9001684"
} |
MED-1890 | Dietary cholesterol from eggs increases the ratio of total cholesterol to high-density lipoprotein cholesterol in humans: a meta-analysis. | BACKGROUND: Several epidemiologic studies found no effect of egg consumption on the risk of coronary heart disease. It is possible that the adverse effect of eggs on LDL-cholesterol is offset by their favorable effect on HDL cholesterol. OBJECTIVE: The objective was to review the effect of dietary cholesterol on the ra... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/11333841"
} |
MED-1914 | Early life stress and telomere length: Investigating the connection and possible mechanisms | How can adverse experiences in early life, such as maltreatment, exert such powerful negative effects on health decades later? The answer may lie in changes to DNA. New research suggests that exposure to stress can accelerate the erosion of DNA segments called telomeres. Shorter telomere length correlates with chronolo... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22991129"
} |
MED-1915 | Work-Related Exhaustion and Telomere Length: A Population-Based Study | Background Psychological stress is suggested to accelerate the rate of biological aging. We investigated whether work-related exhaustion, an indicator of prolonged work stress, is associated with accelerated biological aging, as indicated by shorter leukocyte telomeres, that is, the DNA-protein complexes that cap chrom... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22808115"
} |
MED-1916 | The association between physical activity in leisure time and leukocyte telomere length. | BACKGROUND: Physical inactivity is an important risk factor for many aging-related diseases. Leukocyte telomere dynamics (telomere length and age-dependent attrition rate) are ostensibly a biological indicator of human aging. We therefore tested the hypothesis that physical activity level in leisure time (over the past... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/18227361"
} |
MED-1917 | Effect of healthy lifestyle behaviors on the association between leukocyte telomere length and coronary artery calcium. | The telomere length is an indicator of biologic aging, and shorter telomeres have been associated with coronary artery calcium (CAC), a validated indicator of coronary atherosclerosis. It is unclear, however, whether healthy lifestyle behaviors affect the relation between telomere length and CAC. In a sample of subject... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/20723641"
} |
MED-1918 | Intensive meditation training, immune cell telomerase activity, and psychological mediators. | BACKGROUND: Telomerase activity is a predictor of long-term cellular viability, which decreases with chronic psychological distress (Epel et al., 2004). Buddhist traditions claim that meditation decreases psychological distress and promotes well-being (e.g., Dalai Lama and Cutler, 2009). Therefore, we investigated the ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21035949"
} |
MED-1919 | Human telomerase model shows the role of the TEN domain in advancing the double helix for the next polymerization step | Telomerases constitute a group of specialized ribonucleoprotein enzymes that remediate chromosomal shrinkage resulting from the “end-replication” problem. Defects in telomere length regulation are associated with several diseases as well as with aging and cancer. Despite significant progress in understanding the roles ... | {
"url": "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111281/"
} |
MED-1920 | Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in ... | Overweight and obesity are major contributors to both type 2 diabetes and cardiovascular disease (CVD). Moreover, individuals with type 2 diabetes who are overweight or obese are at particularly high risk for CVD morbidity and mortality. Although short-term weight loss has been shown to ameliorate obesity-related metab... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/14500058"
} |
MED-1921 | Intake of Small-to-Medium-Chain Saturated Fatty Acids Is Associated with Peripheral Leukocyte Telomere Length in Postmenopausal Women | Dietary factors, including dietary fat, may affect the biological aging process, as reflected by the shortening of telomere length (TL), by affecting levels of oxidative stress and inflammatory responses. We examined the direct relations of total and types of dietary fats and fat-rich foods to peripheral leukocyte TL. ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23616516"
} |
MED-1922 | Stress and Telomere Biology: A Lifespan Perspective | In the past decade, the growing field of telomere science has opened exciting new avenues for understanding the cellular and molecular substrates of stress and stress-related aging processes ver the lifespan. Shorter telomere length is associated with advancing chronological age and also increased disease morbidity and... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23639252"
} |
MED-1923 | Loving-Kindness Meditation practice associated with longer telomeres in women. | Relatively short telomere length may serve as a marker of accelerated aging, and shorter telomeres have been linked to chronic stress. Specific lifestyle behaviors that can mitigate the effects of stress might be associated with longer telomere lengths. Previous research suggests a link between behaviors that focus on ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23602876"
} |
MED-1924 | Saturated fatty acid metabolism is key link between cell division, cancer, and senescence in cellular and whole organism aging | Cellular senescence is an in vivo and in vitro phenomenon, accompanied by physiological changes including cessation of division and disturbances of organelle structure and function. Review of the literature was undertaken to determine whether there is evidence that whole organism aging and cell senescence share a commo... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/20431990"
} |
MED-1926 | Habitual physical exercise has beneficial effects on telomere length in postmenopausal women. | OBJECTIVE: It has been reported that women benefit from the maintenance of telomere length by estrogen. Exercise may favorably influence telomere length, although results are inconsistent regarding the duration and type of exercise and the cell type used to measure telomere length. The purpose of this study was to inve... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22668817"
} |
MED-1928 | Telomeres, lifestyle, cancer, and aging | Purpose of review There has been growing evidence that lifestyle factors may affect the health and lifespan of an individual by affecting telomere length. The purpose of this review was to highlight the importance of telomeres in human health and aging and to summarize possible lifestyle factors that may affect health ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21102320"
} |
MED-1929 | A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: Effects on mental health, cognition, and telomerase activity | BACKGROUND This study examined the effects of brief daily yogic meditation on mental health, cognitive functioning, and immune cell telomerase activity in family dementia caregivers with mild depressive symptoms. METHODS Thirty-nine family dementia caregivers (mean age 60.3 years old (SD=10.2)) were randomized to pract... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22407663"
} |
MED-1930 | Leukocyte telomere length and its relation to food and nutrient intake in an elderly population. | BACKGROUND/OBJECTIVES: Shorter leukocyte telomere length (LTL) is associated with several chronic diseases, but only a few studies have assessed the association between dietary factors and LTL. Our objective was to study the association between fats, fruits, vegetables and LTL in a cross-sectional study design. We hypo... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23073262"
} |
MED-1931 | Accelerated Telomere Erosion Is Associated with a Declining Immune Function of Caregivers of Alzheimer’s Disease Patients | Caregivers of Alzheimer’s disease patients endure chronic stress associated with a decline of immune function. To assess the psychological and immunological changes of caregivers, we compared depressive symptoms, PBMC composition, in vitro activation-induced proliferation and cytokine production, and telomere length an... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/17785865"
} |
MED-1932 | Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study | There is increasing interest in discovering mechanisms that mediate the effects of childhood stress on late-life disease morbidity and mortality. Previous studies have suggested one potential mechanism linking stress to cellular aging, disease and mortality in humans: telomere erosion. We examined telomere erosion in r... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22525489"
} |
MED-1933 | From the Cover: Accelerated telomere shortening in response to life stress | Numerous studies demonstrate links between chronic stress and indices of poor health, including risk factors for cardiovascular disease and poorer immune function. Nevertheless, the exact mechanisms of how stress gets “under the skin” remain elusive. We investigated the hypothesis that stress impacts health by modulati... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/15574496"
} |
MED-1934 | Independent and Combined Effects of Dietary Weight Loss and Exercise on Leukocyte Telomere Length in Postmenopausal Women | Objective Investigate the effects of 12 months of dietary weight loss and/or aerobic exercise on leukocyte telomere length in postmenopausal women. Design and Methods 439 overweight or obese women (50–75 y) were randomized to: i) dietary weight loss (N=118); ii) aerobic exercise (N=117), iii) diet + exercise (N=117), o... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23640743"
} |
MED-1935 | Diet-related telomere shortening and chromosome stability | Recent evidences have highlighted an influence of micronutrients in the maintenance of telomere length (TL). In order to explore whether diet-related telomere shortening had any physiological relevance and was accompanied by significant damage in the genome, in the present study, TL was assessed by terminal restriction... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21857007"
} |
MED-1936 | Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall. | BACKGROUND: The underlying molecular mechanisms of the vasculoprotective effects of physical exercise are incompletely understood. Telomere erosion is a central component of aging, and telomere-associated proteins regulate cellular senescence and survival. This study examines the effects of exercising on vascular telom... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/19948976"
} |
MED-1937 | Effects of turmeric on Alzheimer's disease with behavioral and psychological symptoms of dementia | We describe here three patients with the Alzheimer's Disease (AD) whose behavioral symptoms were improved remarkably as a result of the turmeric treatment, which is the traditional Indian medicine. Their cognitive decline and Behavioral and Psychological Symptoms of Dementia (BPSD) were very severe. All three patients ... | {
"url": "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665200/"
} |
MED-1939 | Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study | Introduction Curcumin is a polyphenolic compound derived from the plant Curcuma Long Lin that has been demonstrated to have antioxidant and anti-inflammatory effects as well as effects on reducing beta-amyloid aggregation. It reduces pathology in transgenic models of Alzheimer's disease (AD) and is a promising candidat... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23107780"
} |
MED-1941 | Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients. | Treatment of Alzheimer's disease (AD) is difficult due to ignorance of its pathogenesis. AD patients have defects in phagocytosis of amyloid-beta (1-42) (Abeta) in vitro by the innate immune cells, monocyte/macrophages and in clearance of Abeta plaques [5]. The natural product curcuminoids enhanced brain clearance of A... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/16988474"
} |
MED-1942 | Curry consumption and cognitive function in the elderly. | Curcumin, from the curry spice turmeric, has been shown to possess potent antioxidant and antiinflammatory properties and to reduce beta-amyloid and plaque burden in experimental studies, but epidemiologic evidence is lacking. The authors investigated the association between usual curry consumption level and cognitive ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/16870699"
} |
MED-1944 | Incidence of Alzheimer's disease in a rural community in India: the Indo-US study. | OBJECTIVE: To determine overall and age-specific incidence rates of AD in a rural, population-based cohort in Ballabgarh, India, and to compare them with those of a reference US population in the Monongahela Valley of Pennsylvania. METHODS: A 2-year, prospective, epidemiologic study of subjects aged > or =55 years util... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/11571321"
} |
MED-1947 | Role of curcumin in idiopathic inflammatory orbital pseudotumours. | The present report, describes for the first time the clinical efficacy of curcumin, the active constituent of rhizomes of Curcuma longa, in the treatment of patients suffering from idiopathic inflammatory orbital pseudotumours. Curcumin was administered orally at a dose of 375 mg/3 times/day orally for a period of 6-22... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/10960899"
} |
MED-1948 | Curcumin and neurodegenerative diseases | Over the last ten years curcumin has been reported to be effective against a wide variety of diseases and is characterized as having anti-carcinogenic, hepatoprotective, thrombosuppressive, cardioprotective, anti-arthritic, and anti-infectious properties. Recent studies performed in both vertebrate and invertebrate mod... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23303664"
} |
MED-1949 | Is very preterm birth a risk factor for adult cardiometabolic disease? | The first infants to experience modern pre- and neonatal care are now in their thirties, an age at which the incidence of cardiometabolic disease is low. However, data from cohorts born preterm prior to the introduction of modern care suggest an increased risk of type 2 diabetes. For young adult cohorts of former very ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24332842"
} |
MED-1950 | Intakes of Garlic and Dried Fruits Are Associated with Lower Risk of Spontaneous Preterm Delivery | Several studies have found associations between microbial infections during pregnancy and preterm delivery (PTD). We investigated the influence of food with antimicrobial and prebiotic components on the risk of spontaneous PTD. A literature search identified microbes associated with spontaneous PTD. Subsequently, 2 mai... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23700347"
} |
MED-1951 | Late preterm birth: a review of medical and neuropsychological childhood outcomes. | Late preterm (LP) birth (34 0/7 - 36 6/7 weeks' gestation) accounts for nearly three-fourths of all preterm births, making this population a sizeable public health concern. The immature fetal development associated with LP delivery increases the risk of mortality and short-term medical complications. Which combination ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/22869055"
} |
MED-1952 | Growing up after extremely preterm birth: lifespan mental health outcomes. | There is growing interest in the long-term mental health sequelae of extremely preterm birth. In this paper we review literature relating to mental health outcomes across the lifespan. Studies conducted in the preschool years, school age and adolescence, and adulthood show continuity in outcomes and point to an increas... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24290907"
} |
MED-1953 | Antimicrobial properties of Allium sativum (garlic). | Although garlic has been used for its medicinal properties for thousands of years, investigations into its mode of action are relatively recent. Garlic has a wide spectrum of actions; not only is it antibacterial, antiviral, antifungal and antiprotozoal, but it also has beneficial effects on the cardiovascular and immu... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/11759674"
} |
MED-1954 | Preterm birth and behaviour problems in infants and preschool-age children: a review of the recent literature. | The behaviour problems of children born preterm at school age are well known, but there have been few studies on the behaviour problems of preterm-born infants during infancy and at preschool age. Fourteen cohort studies published in PubMed and PsycINFO between 2000 and 2012 were reviewed with a focus on the type, occu... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23521214"
} |
MED-1955 | Maternal dietary patterns and preterm delivery: results from large prospective cohort study | Objective To examine whether an association exists between maternal dietary patterns and risk of preterm delivery. Design Prospective cohort study. Setting Norway, between 2002 and 2008. Participants 66 000 pregnant women (singletons, answered food frequency questionnaire, no missing information about parity or previou... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24609054"
} |
MED-1956 | Elevated TCDD in chicken eggs and farm-raised catfish fed a diet with ball clay from a Southern United States mine. | The U.S. Food and Drug Administration (FDA) terminated the use of ball clay from a mine in Mississippi as an additive in animal feed after discovering nanogram per gram concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD). The FDA collected chicken eggs and farm-raised catfish in affected areas and thro... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/10585021"
} |
MED-1957 | PCDD and PCDF contamination in catfish feed from Arkansas, USA. | One combined catfish feed sample from Arkansas, USA, and its eight ingredients were analyzed for PCDDs and PCDFs. One of the ingredients, soybean meal, was highly contaminated by PCDDs, especially the toxic 2,3,7,8-substituted congeners, e.g., 7.3 pg/g dry weight or 370 pg/g lipid for the 2,3,7,8-tetra CDD. The I-TEQ v... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/9745703"
} |
MED-1958 | Congener-specific levels of dioxins and dibenzofurans in U.S. food and estimated daily dioxin toxic equivalent intake. | Food, especially meat, milk, and fish, is the immediate source of almost all polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and dioxinlike compounds in the general population. To estimate intake of these highly toxic compounds, we performed congener-specific dioxin analyses for the first time on U.S.... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/9738211"
} |
MED-1959 | Dioxin congener patterns in commercial catfish from the United States and the indication of mineral clays as the potential source. | Since 1991 the US Department of Agriculture (USDA) has conducted annual surveys of pesticide residues in foods under the Agricultural Marketing Service's Pesticide Data Program (PDP). To assess chemical residues in domestically marketed catfish products, 1479 catfish samples were collected during the 2008-2010 PDPs. A ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23234292"
} |
MED-1960 | PCDD, PCDF, and PCB in farm-raised catfish from southeast United States--concentrations, sources, and CYP1A induction. | Nine catfish fillets, three catfish nuggets, two feed samples, and one pond sediment were analyzed for PCDD, PCDF, and PCB. Farm-raised catfish from Mississippi, Alabama, and Arkansas contained significant levels of 2,3,7,8-substituted PCDD and PCDF. In addition, a large number of non-2,3,7,8-substituted congeners were... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/9828294"
} |
MED-1961 | Reducing exposure to dioxins and related compounds through foods in the next generation. | Dioxins and related compounds are undesirable and unintended contaminants in the food supply, and dietary intake is the major route of exposure. Reducing dietary exposure to dioxins among the most vulnerable segments of the population (i.e., pregnant women, infants, and young girls) is an effective strategy for reducin... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/17002236"
} |
MED-1962 | The concentration and distribution of 2,3,7,8-dibenzo-p-dioxins/-furans in chickens. | The concentrations of the 2,3,7,8-Cl substituted dibenzo-p-dioxins/-furans (PCDDs/PCDFs) were determined in the edible tissues of whole chicken fryers and compared with the values found in their abdominal fat. The values are presented both on a whole weight basis and on a lipid adjusted basis for each tissue. While the... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/10665435"
} |
MED-1963 | Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/PCDF) in food samples collected in southern Mississippi, USA. | In 1994, we analyzed 43 foodstuff samples from local supermarkets in southern Mississippi, USA, for PCDD/PCDF. 2,3,7,8-Cl4DD could be quantified in 31 of these samples. On a lipid basis, levels in meat (0.53-1.10 pg I-TEQ/g) and dairy products (0.42-1.10 pg I-TEQ/g) were slightly lower than those reported from other in... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/9134675"
} |
MED-1966 | Effects of dietary cholesterol on serum cholesterol: a meta-analysis and review. | Attempts to estimate the effects of dietary cholesterol on serum cholesterol by meta-analysis have not previously included baseline together with added dietary cholesterol in a mathematical model. Mean reported changes in serum cholesterol from 27 studies in which controlled diets were supplied by a metabolic kitchen p... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/1534437"
} |
MED-1968 | Effects of increasing amounts of dietary cholesterol on postprandial lipemia and lipoproteins in human subjects. | Our aim was to determine the effects of increasing amounts of dietary cholesterol (0-710 mg) on the postprandial plasma lipid responses and lipoprotein changes in normolipidemic human subjects. Ten subjects were fed five different test meals in a random order: one meal did not contain fat or cholesterol while the four ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/7868978"
} |
MED-1977 | Colonization of butchers with livestock-associated methicillin-resistant Staphylococcus aureus. | Reports have documented colonization of swine in Europe, North America and more recently in China with livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA). Contamination of pig farmers, veterinarians and abattoir workers with these strains has been observed. However, although contamination levels... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23279691"
} |
MED-1978 | High-density livestock operations, crop field application of manure, and risk of community-associated methicillin-resistant Staphylococcus aureus infection, Pennsylvania, USA | Context Nearly 80% of antibiotics in the United States are sold for use in livestock feeds. The manure produced by these livestock contains antibiotic-resistant bacteria, resistance genes, and antibiotics, and is subsequently applied to crop fields where it may put community members at risk for antibiotic-resistant inf... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24043228"
} |
MED-1979 | From pig to pork: methicillin-resistant Staphylococcus aureus in the pork production chain. | Methicillin-resistant Staphylococcus aureus (MRSA) is a major global public health concern and could be a food safety issue. Recurrent reports have documented that pig herds are an important reservoir for MRSA, specifically the livestock-associated sequence type 398. The high prevalence of MRSA in pig primary productio... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23726208"
} |
MED-1980 | Rapid Detection of Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae | Enterobacterial strains producing clavulanic-acid-inhibited extended-spectrum β-lactamases (ESBLs) are increasingly reported worldwide. Conventional detection of ESBL production remains time-consuming (24 to 48 h). Therefore, the ESBL NDP (Nordmann/Dortet/Poirel) test was developed for a rapid identification of ESBLs i... | {
"url": "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421789/"
} |
MED-1981 | Antibiotic resistance-the need for global solutions. | The causes of antibiotic resistance are complex and include human behaviour at many levels of society; the consequences affect everybody in the world. Similarities with climate change are evident. Many efforts have been made to describe the many different facets of antibiotic resistance and the interventions needed to ... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24252483"
} |
MED-1982 | Contamination of hands with methicillin-resistant Staphylococcus aureus after contact with environmental surfaces and after contact with the skin o... | In a study of 40 methicillin-resistant Staphylococcus aureus (MRSA) carriers, hand contamination was equally likely after contact with commonly examined skin sites and commonly touched environmental surfaces in patient rooms (40% vs 45%). These findings suggest that contaminated surfaces may be an important source of M... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/21460476"
} |
MED-1983 | Transfer of methicillin-resistant Staphylococcus aureus from retail pork products onto food contact surfaces and the potential for consumer exposure. | Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogen that has developed resistance to beta-lactam antibiotics and has been isolated at low population numbers in retail meat products. The objectives of this study were to estimate the potential transfer of MRSA from contaminated retail pork products to food c... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/24290687"
} |
MED-1985 | Attained height of lacto-ovo vegetarian children and adolescents. | The relationship between diet and attained height was studied in children and adolescents in Southern California. Diet pattern was determined from an extensive food frequency questionnaire in 1765 Caucasian children of 7-18 years, attending state schools (452 m and 443 f) and Seventh-day Adventist schools (427 m and 44... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/1855500"
} |
MED-1986 | Long-term morbidity and mortality of overweight adolescents. A follow-up of the Harvard Growth Study of 1922 to 1935. | BACKGROUND: Overweight in adults is associated with increased morbidity and mortality. In contrast, the long-term effect of overweight in adolescence on morbidity and mortality is not known. METHODS: We studied the relation between overweight and morbidity and mortality in 508 lean or overweight adolescents 13 to 18 ye... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/1406836"
} |
MED-1987 | Management of type 2 diabetes mellitus in children and adolescents. | OBJECTIVE: Over the last 3 decades, the prevalence of childhood obesity has increased dramatically in North America, ushering in a variety of health problems, including type 2 diabetes mellitus (T2DM), which previously was not typically seen until much later in life. This technical report describes, in detail, the proc... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/23359584"
} |
MED-1988 | Pediatrician's role in screening and treatment: bullying, prediabetes, oral health. | PURPOSE OF REVIEW: To review recent literature on important topics in pediatric office practice: bullying, screening for the prediabetic state, and pediatric oral health. RECENT FINDINGS: Recent literature shows that bullying behaviors are common in children as young as kindergarten age, that there is a strong associat... | {
"url": "http://www.ncbi.nlm.nih.gov/pubmed/17099367"
} |
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